#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q60876 uniprotkb:P63073 intact:EBI-398674|uniprotkb:Q3TDS8|uniprotkb:Q9CZ40|ensembl:ENSMUSP00000033880 intact:EBI-2000006|uniprotkb:P20415|ensembl:ENSMUSP00000029803 psi-mi:4ebp1_mouse(display_long)|uniprotkb:Eif4ebp1(gene name)|psi-mi:Eif4ebp1(display_short)|uniprotkb:Phosphorylated heat- and acid-stable protein regulated by insulin 1(gene name synonym) psi-mi:if4e_mouse(display_long)|uniprotkb:Eif4e(gene name)|psi-mi:Eif4e(display_short)|uniprotkb:eIF-4F 25 kDa subunit(gene name synonym) psi-mi:"MI:0096"(pull down) Feldman et al. (2009) pubmed:19209957|doi:10.1371/journal.pbio.1000038|imex:IM-14147 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15757115|imex:IM-14147-1|dip:DIP-102801E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_031944.3|dip:DIP-32577N|go:"GO:0071549"(cellular response to dexamethasone stimulus)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099524"(postsynaptic cytosol)|go:"GO:1990928"(response to amino acid starvation)|interpro:IPR008606(Eukaryotic translation initiation factor 4E binding)|interpro:IPR037582|reactome:R-MMU-166208|reactome:R-MMU-72662|ensembl:ENSMUSG00000031490(gene)|ensembl:ENSMUST00000033880(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0002192"(IRES-dependent translational initiation of linear mRNA)|go:"GO:0002931"(response to ischemia)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0008190"(eukaryotic initiation factor 4E binding)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0030324"(lung development)|go:"GO:0030371"(translation repressor activity)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0031929"(TOR signaling)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045471"(response to ethanol)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0045947"(negative regulation of translational initiation)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0071456"(cellular response to hypoxia) refseq:NP_031943.3|dip:DIP-42768N|ensembl:ENSMUSG00000028156(gene)|ensembl:ENSMUST00000029803(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0000932"(P-body)|go:"GO:0001662"(behavioral fear response)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005845"(mRNA cap binding complex)|go:"GO:0006417"(regulation of translation)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016281"(eukaryotic translation initiation factor 4F complex)|go:"GO:0016442"(RISC complex)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0019899"(enzyme binding)|go:"GO:0030324"(lung development)|go:"GO:0031370"(eukaryotic initiation factor 4G binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033391"(chromatoid body)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0045182"(translation regulator activity)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099524"(postsynaptic cytosol)|go:"GO:0099578"(regulation of translation at postsynapse, modulating synaptic transmission)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001040("Eukaryotic translation initiation factor 4E (eIF-4E)")|interpro:IPR019770|interpro:IPR023398|rcsb pdb:1EJ1|rcsb pdb:1EJ4|rcsb pdb:1EJH|rcsb pdb:1L8B|rcsb pdb:5BXV|rcsb pdb:5J5O|rcsb pdb:5J5Y|rcsb pdb:5M7V|rcsb pdb:5M7W|rcsb pdb:5M7X|rcsb pdb:5M7Z|rcsb pdb:5M80|rcsb pdb:5M81|rcsb pdb:5M83|rcsb pdb:5M84|rcsb pdb:5OSX|rcsb pdb:6GKJ|rcsb pdb:6GKK|rcsb pdb:6GKL|rcsb pdb:6U06|rcsb pdb:6U09|rcsb pdb:6YLR|rcsb pdb:6YLT|rcsb pdb:6YLV|reactome:R-MMU-1169408|reactome:R-MMU-156827|reactome:R-MMU-159227|reactome:R-MMU-159230|reactome:R-MMU-159231|reactome:R-MMU-166208|reactome:R-MMU-429947|reactome:R-MMU-72649|reactome:R-MMU-72662|reactome:R-MMU-72702|reactome:R-MMU-72706 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse)|taxid:10090(Mus musculus) - 2017/08/06 2017/08/10 rogid:EYSRK9c019DQ14TAyF1cvmdVll410090 rogid:DnMmfgiMq6RHbSuRPwy/TaoeySU10090 rigid:HNJBvhI24vjhqC5VESCzESawS0s false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot)