#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q14061	uniprotkb:Q8N4Q1-1	intact:EBI-711311|uniprotkb:D3DN84|ensembl:ENSP00000261070|ensembl:ENSP00000417805|ensembl:ENSP00000417923|uniprotkb:Q3MHD6|uniprotkb:B2R5D2	intact:EBI-15755238|ensembl:ENSP00000380122	psi-mi:cox17_human(display_long)|uniprotkb:COX17(gene name)|psi-mi:COX17(display_short)	psi-mi:q8n4q1-1(display_long)|uniprotkb:CHCHD4(gene name)|psi-mi:CHCHD4(display_short)|uniprotkb:MIA40(gene name synonym)|uniprotkb:Coiled-coil-helix-coiled-coil-helix domain-containing protein 4(gene name synonym)	psi-mi:"MI:0077"(nuclear magnetic resonance)	Banci et al. (2009)	pubmed:19182799|doi:10.1038/nsmb.1553|imex:IM-14258	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0945"(oxidoreductase activity electron transfer reaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15755245|imex:IM-14258-1|dip:DIP-103034E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005685.1|ensembl:ENSG00000138495(gene)|ensembl:ENST00000261070(transcript)|ensembl:ENST00000468918(transcript)|ensembl:ENST00000497116(transcript)|go:"GO:0005507"(copper ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0006091"(generation of precursor metabolites and energy)|go:"GO:0006825"(copper ion transport)|go:"GO:0007420"(brain development)|go:"GO:0007507"(heart development)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016531"(copper chaperone activity)|go:"GO:0033617"(mitochondrial cytochrome c oxidase assembly)|go:"GO:1903136"(cuprous ion binding)|go:"GO:1904960"(positive regulation of cytochrome-c oxidase activity)|interpro:IPR007745(Cytochrome C oxidase copper chaperone)|interpro:IPR009069(MTCP1)|rcsb pdb:2L0Y|rcsb pdb:2LGQ|rcsb pdb:2RN9|rcsb pdb:2RNB|reactome:R-HSA-1268020|dip:DIP-46087N	intact:EBI-2562213(isoform-parent)|ensembl:ENSG00000163528(gene)|ensembl:ENST00000396914(transcript)	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/06	2017/08/10	rogid:DduAgG449PBuqu3MF3MBChmg6t09606	rogid:ACH8CTQRjTwq7nz6toGTrn3VHlE9606	rigid:ZJdFLCmbkomoscll9HS85r52ZZQ	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q14061	uniprotkb:Q8N4Q1-1	intact:EBI-711311|uniprotkb:D3DN84|ensembl:ENSP00000261070|ensembl:ENSP00000417805|ensembl:ENSP00000417923|uniprotkb:Q3MHD6|uniprotkb:B2R5D2	intact:EBI-15755238|ensembl:ENSP00000380122	psi-mi:cox17_human(display_long)|uniprotkb:COX17(gene name)|psi-mi:COX17(display_short)	psi-mi:q8n4q1-1(display_long)|uniprotkb:CHCHD4(gene name)|psi-mi:CHCHD4(display_short)|uniprotkb:MIA40(gene name synonym)|uniprotkb:Coiled-coil-helix-coiled-coil-helix domain-containing protein 4(gene name synonym)	psi-mi:"MI:0096"(pull down)	Banci et al. (2009)	pubmed:19182799|doi:10.1038/nsmb.1553|imex:IM-14258	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15755288|imex:IM-14258-3|dip:DIP-103034E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005685.1|ensembl:ENSG00000138495(gene)|ensembl:ENST00000261070(transcript)|ensembl:ENST00000468918(transcript)|ensembl:ENST00000497116(transcript)|go:"GO:0005507"(copper ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0006091"(generation of precursor metabolites and energy)|go:"GO:0006825"(copper ion transport)|go:"GO:0007420"(brain development)|go:"GO:0007507"(heart development)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016531"(copper chaperone activity)|go:"GO:0033617"(mitochondrial cytochrome c oxidase assembly)|go:"GO:1903136"(cuprous ion binding)|go:"GO:1904960"(positive regulation of cytochrome-c oxidase activity)|interpro:IPR007745(Cytochrome C oxidase copper chaperone)|interpro:IPR009069(MTCP1)|rcsb pdb:2L0Y|rcsb pdb:2LGQ|rcsb pdb:2RN9|rcsb pdb:2RNB|reactome:R-HSA-1268020|dip:DIP-46087N	intact:EBI-2562213(isoform-parent)|ensembl:ENSG00000163528(gene)|ensembl:ENST00000396914(transcript)	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/06	2017/08/10	rogid:DduAgG449PBuqu3MF3MBChmg6t09606	rogid:ACH8CTQRjTwq7nz6toGTrn3VHlE9606	rigid:ZJdFLCmbkomoscll9HS85r52ZZQ	false	-	glutathione s tranferase tag:?-?	-	-	psi-mi:"MI:0833"(autoradiography)	psi-mi:"MI:0833"(autoradiography)
uniprotkb:P87108	uniprotkb:Q8N4Q1-1	intact:EBI-9115|ensemblfungi:YHR005C-A|uniprotkb:D3DKU9	intact:EBI-15755238|ensembl:ENSP00000380122	psi-mi:tim10_yeast(display_long)|uniprotkb:MRS11(gene name synonym)|uniprotkb:YHR005BC(orf name)|uniprotkb:YHR005C-A(locus name)|uniprotkb:TIM10(gene name)|psi-mi:TIM10(display_short)|uniprotkb:Mitochondrial intermembrane protein MRS11(gene name synonym)	psi-mi:q8n4q1-1(display_long)|uniprotkb:CHCHD4(gene name)|psi-mi:CHCHD4(display_short)|uniprotkb:MIA40(gene name synonym)|uniprotkb:Coiled-coil-helix-coiled-coil-helix domain-containing protein 4(gene name synonym)	psi-mi:"MI:0096"(pull down)	Banci et al. (2009)	pubmed:19182799|doi:10.1038/nsmb.1553|imex:IM-14258	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15755309|imex:IM-14258-4|dip:DIP-103035E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YHR005C-A(gene)|ensemblfungi:YHR005C-A_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0042719"(mitochondrial intermembrane space protein transporter complex)|go:"GO:0045039"(protein insertion into mitochondrial inner membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0140318"(protein transporter activity)|interpro:IPR004217(Zinc finger, Tim10/DDP-type)|interpro:IPR027100|interpro:IPR035427|rcsb pdb:3DXR|rcsb pdb:6LO8|reactome:R-SCE-1268020|refseq:NP_011869.1|sgd:S000003530|dip:DIP-1141N|mint:P87108	intact:EBI-2562213(isoform-parent)|ensembl:ENSG00000163528(gene)|ensembl:ENST00000396914(transcript)	psi-mi:"MI:0465"(dip)	crc64:70DD4764B944FF17	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/06	2017/08/10	rogid:3AGstULCT5EBmHEk0EGsz9Rk9YA559292	rogid:ACH8CTQRjTwq7nz6toGTrn3VHlE9606	rigid:+PhMf8J8YQ3ZcrFPbtOSsJDq5wQ	false	-	glutathione s tranferase tag:?-?	-	-	psi-mi:"MI:0833"(autoradiography)	psi-mi:"MI:0833"(autoradiography)
uniprotkb:P36046	uniprotkb:P87108	intact:EBI-26978|uniprotkb:D6VX05|ensemblfungi:YKL195W	intact:EBI-9115|ensemblfungi:YHR005C-A|uniprotkb:D3DKU9	psi-mi:mia40_yeast(display_long)|uniprotkb:YKL195W(locus name)|uniprotkb:MIA40(gene name)|psi-mi:MIA40(display_short)|uniprotkb:TIM40(gene name synonym)|uniprotkb:Mitochondrial import inner membrane translocase TIM40(gene name synonym)	psi-mi:tim10_yeast(display_long)|uniprotkb:MRS11(gene name synonym)|uniprotkb:YHR005BC(orf name)|uniprotkb:YHR005C-A(locus name)|uniprotkb:TIM10(gene name)|psi-mi:TIM10(display_short)|uniprotkb:Mitochondrial intermembrane protein MRS11(gene name synonym)	psi-mi:"MI:0096"(pull down)	Banci et al. (2009)	pubmed:19182799|doi:10.1038/nsmb.1553|imex:IM-14258	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15755262|imex:IM-14258-2|dip:DIP-103036E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012726.2|sgd:S000001678|mint:P36046|dip:DIP-5432N|ensemblfungi:YKL195W(gene)|ensemblfungi:YKL195W_mRNA(transcript)|go:"GO:0003756"(protein disulfide isomerase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0006457"(protein folding)|go:"GO:0015035"(protein-disulfide reductase activity)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0016972"(thiol oxidase activity)|go:"GO:0022417"(protein maturation by protein folding)|go:"GO:0031305"(integral component of mitochondrial inner membrane)|go:"GO:0045041"(protein import into mitochondrial intermembrane space)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding)|interpro:IPR010625(CHCH)|interpro:IPR039289|rcsb pdb:2ZXT|rcsb pdb:3A3C	ensemblfungi:YHR005C-A(gene)|ensemblfungi:YHR005C-A_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0042719"(mitochondrial intermembrane space protein transporter complex)|go:"GO:0045039"(protein insertion into mitochondrial inner membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0140318"(protein transporter activity)|interpro:IPR004217(Zinc finger, Tim10/DDP-type)|interpro:IPR027100|interpro:IPR035427|rcsb pdb:3DXR|rcsb pdb:6LO8|reactome:R-SCE-1268020|refseq:NP_011869.1|sgd:S000003530|dip:DIP-1141N|mint:P87108	psi-mi:"MI:0465"(dip)	crc64:5904E8D0213D6EFA	crc64:70DD4764B944FF17	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/06	2017/08/10	rogid:h/qutsTcZkAqeNJAcTyWJ3FfTrQ559292	rogid:3AGstULCT5EBmHEk0EGsz9Rk9YA559292	rigid:fZu/P+8W1n47dNW8mtL6jZ1z2V0	false	mutation disrupting interaction:298-298,296-296|mutation decreasing interaction:298-298|glutathione s tranferase tag:n-n	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q14061	uniprotkb:P36046	intact:EBI-711311|uniprotkb:D3DN84|ensembl:ENSP00000261070|ensembl:ENSP00000417805|ensembl:ENSP00000417923|uniprotkb:Q3MHD6|uniprotkb:B2R5D2	intact:EBI-26978|uniprotkb:D6VX05|ensemblfungi:YKL195W	psi-mi:cox17_human(display_long)|uniprotkb:COX17(gene name)|psi-mi:COX17(display_short)	psi-mi:mia40_yeast(display_long)|uniprotkb:YKL195W(locus name)|uniprotkb:MIA40(gene name)|psi-mi:MIA40(display_short)|uniprotkb:TIM40(gene name synonym)|uniprotkb:Mitochondrial import inner membrane translocase TIM40(gene name synonym)	psi-mi:"MI:0096"(pull down)	Banci et al. (2009)	pubmed:19182799|doi:10.1038/nsmb.1553|imex:IM-14258	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15755330|imex:IM-14258-5|dip:DIP-103037E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005685.1|ensembl:ENSG00000138495(gene)|ensembl:ENST00000261070(transcript)|ensembl:ENST00000468918(transcript)|ensembl:ENST00000497116(transcript)|go:"GO:0005507"(copper ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0006091"(generation of precursor metabolites and energy)|go:"GO:0006825"(copper ion transport)|go:"GO:0007420"(brain development)|go:"GO:0007507"(heart development)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016531"(copper chaperone activity)|go:"GO:0033617"(mitochondrial cytochrome c oxidase assembly)|go:"GO:1903136"(cuprous ion binding)|go:"GO:1904960"(positive regulation of cytochrome-c oxidase activity)|interpro:IPR007745(Cytochrome C oxidase copper chaperone)|interpro:IPR009069(MTCP1)|rcsb pdb:2L0Y|rcsb pdb:2LGQ|rcsb pdb:2RN9|rcsb pdb:2RNB|reactome:R-HSA-1268020|dip:DIP-46087N	refseq:NP_012726.2|sgd:S000001678|mint:P36046|dip:DIP-5432N|ensemblfungi:YKL195W(gene)|ensemblfungi:YKL195W_mRNA(transcript)|go:"GO:0003756"(protein disulfide isomerase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0006457"(protein folding)|go:"GO:0015035"(protein-disulfide reductase activity)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0016972"(thiol oxidase activity)|go:"GO:0022417"(protein maturation by protein folding)|go:"GO:0031305"(integral component of mitochondrial inner membrane)|go:"GO:0045041"(protein import into mitochondrial intermembrane space)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding)|interpro:IPR010625(CHCH)|interpro:IPR039289|rcsb pdb:2ZXT|rcsb pdb:3A3C	psi-mi:"MI:0465"(dip)	-	crc64:5904E8D0213D6EFA	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/06	2017/08/10	rogid:DduAgG449PBuqu3MF3MBChmg6t09606	rogid:h/qutsTcZkAqeNJAcTyWJ3FfTrQ559292	rigid:CkYTL8lnZtZIcfol07ZNS5+lD5I	false	-	mutation disrupting interaction:298-298,296-296|mutation decreasing interaction:298-298|glutathione s tranferase tag:n-n	-	-	psi-mi:"MI:0833"(autoradiography)	psi-mi:"MI:0833"(autoradiography)