#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P17967 uniprotkb:P38888 intact:EBI-13012|uniprotkb:D6VQX3|ensemblfungi:YCL043C intact:EBI-24256|uniprotkb:D3DLF3|ensemblfungi:YHR204W psi-mi:pdi_yeast(display_long)|uniprotkb:TRG1(gene name synonym)|uniprotkb:YCL313(orf name)|uniprotkb:PDI1(gene name)|psi-mi:PDI1(display_short)|uniprotkb:MFP1(gene name synonym)|uniprotkb:Thioredoxin-related glycoprotein 1(gene name synonym)|uniprotkb:YCL43C(orf name)|uniprotkb:YCL043C(locus name) psi-mi:mnl1_yeast(display_long)|uniprotkb:MNL1(gene name)|psi-mi:MNL1(display_short)|uniprotkb:HTM1(gene name synonym)|uniprotkb:YHR204W(locus name) psi-mi:"MI:0004"(affinity chromatography technology) Clerc et al. (2009) imex:IM-26181|pubmed:19124653 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-16411782|imex:IM-26181-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009887.1|sgd:S000000548|mint:P17967|dip:DIP-4978N|ensemblfungi:YCL043C(gene)|ensemblfungi:YCL043C_mRNA(transcript)|go:"GO:0003756"(protein disulfide isomerase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0006457"(protein folding)|go:"GO:0015035"(protein-disulfide reductase activity)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0036508"(protein alpha-1,2-demannosylation)|go:"GO:0051082"(unfolded protein binding)|go:"GO:1904382"(mannose trimming involved in glycoprotein ERAD pathway)|interpro:IPR005792(Protein disulphide isomerase)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR017937|interpro:IPR036249|rcsb pdb:2B5E|rcsb pdb:3BOA|reactome:R-SCE-901042 sgd:S000001247|refseq:NP_012074.3|dip:DIP-1890N|mint:P38888|ensemblfungi:YHR204W(gene)|ensemblfungi:YHR204W_mRNA(transcript)|go:"GO:0004571"(mannosyl-oligosaccharide 1,2-alpha-mannosidase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0016020"(membrane)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0036508"(protein alpha-1,2-demannosylation)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0097466"(ubiquitin-dependent glycoprotein ERAD pathway)|go:"GO:1904380"(endoplasmic reticulum mannose trimming)|go:"GO:1904382"(mannose trimming involved in glycoprotein ERAD pathway)|interpro:IPR001382(Glycoside hydrolase, family 47)|interpro:IPR012341(Six-hairpin glycosidase)|interpro:IPR036026|interpro:IPR044674 - crc64:69CF3E05D7F74C94 - figure legend:Fig. 6A Supp. Table 1|comment:Bound proteins were released from the column by TEV-cleavage of the myc tag on MNL1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2017/09/05 2017/09/05 rogid:tyy52cf76yr9hl+9ggGGS4zDO/A559292 rogid:X8SFT/OIFa+RJWosZzSqkhDPMlo559292 rigid:JpQirWOQwpm9c+YQWbQIjAt1tnI false - calmodulin binding peptide plus protein a tag:c-c|myc tag:c-c - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P17967 uniprotkb:P38888 intact:EBI-13012|uniprotkb:D6VQX3|ensemblfungi:YCL043C intact:EBI-24256|uniprotkb:D3DLF3|ensemblfungi:YHR204W psi-mi:pdi_yeast(display_long)|uniprotkb:TRG1(gene name synonym)|uniprotkb:YCL313(orf name)|uniprotkb:PDI1(gene name)|psi-mi:PDI1(display_short)|uniprotkb:MFP1(gene name synonym)|uniprotkb:Thioredoxin-related glycoprotein 1(gene name synonym)|uniprotkb:YCL43C(orf name)|uniprotkb:YCL043C(locus name) psi-mi:mnl1_yeast(display_long)|uniprotkb:MNL1(gene name)|psi-mi:MNL1(display_short)|uniprotkb:HTM1(gene name synonym)|uniprotkb:YHR204W(locus name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Clerc et al. (2009) imex:IM-26181|pubmed:19124653 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-16411837|imex:IM-26181-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009887.1|sgd:S000000548|mint:P17967|dip:DIP-4978N|ensemblfungi:YCL043C(gene)|ensemblfungi:YCL043C_mRNA(transcript)|go:"GO:0003756"(protein disulfide isomerase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0006457"(protein folding)|go:"GO:0015035"(protein-disulfide reductase activity)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0036508"(protein alpha-1,2-demannosylation)|go:"GO:0051082"(unfolded protein binding)|go:"GO:1904382"(mannose trimming involved in glycoprotein ERAD pathway)|interpro:IPR005792(Protein disulphide isomerase)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR017937|interpro:IPR036249|rcsb pdb:2B5E|rcsb pdb:3BOA|reactome:R-SCE-901042 sgd:S000001247|refseq:NP_012074.3|dip:DIP-1890N|mint:P38888|ensemblfungi:YHR204W(gene)|ensemblfungi:YHR204W_mRNA(transcript)|go:"GO:0004571"(mannosyl-oligosaccharide 1,2-alpha-mannosidase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0016020"(membrane)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0036508"(protein alpha-1,2-demannosylation)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0097466"(ubiquitin-dependent glycoprotein ERAD pathway)|go:"GO:1904380"(endoplasmic reticulum mannose trimming)|go:"GO:1904382"(mannose trimming involved in glycoprotein ERAD pathway)|interpro:IPR001382(Glycoside hydrolase, family 47)|interpro:IPR012341(Six-hairpin glycosidase)|interpro:IPR036026|interpro:IPR044674 - crc64:69CF3E05D7F74C94 - figure legend:Fig. 6B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2017/09/05 2017/09/05 rogid:tyy52cf76yr9hl+9ggGGS4zDO/A559292 rogid:X8SFT/OIFa+RJWosZzSqkhDPMlo559292 rigid:JpQirWOQwpm9c+YQWbQIjAt1tnI false necessary binding region:460-522|ha tag:?-? myc tag:c-c - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P17967 uniprotkb:P38888 intact:EBI-13012|uniprotkb:D6VQX3|ensemblfungi:YCL043C intact:EBI-24256|uniprotkb:D3DLF3|ensemblfungi:YHR204W psi-mi:pdi_yeast(display_long)|uniprotkb:TRG1(gene name synonym)|uniprotkb:YCL313(orf name)|uniprotkb:PDI1(gene name)|psi-mi:PDI1(display_short)|uniprotkb:MFP1(gene name synonym)|uniprotkb:Thioredoxin-related glycoprotein 1(gene name synonym)|uniprotkb:YCL43C(orf name)|uniprotkb:YCL043C(locus name) psi-mi:mnl1_yeast(display_long)|uniprotkb:MNL1(gene name)|psi-mi:MNL1(display_short)|uniprotkb:HTM1(gene name synonym)|uniprotkb:YHR204W(locus name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Clerc et al. (2009) imex:IM-26181|pubmed:19124653 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-16411890|imex:IM-26181-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009887.1|sgd:S000000548|mint:P17967|dip:DIP-4978N|ensemblfungi:YCL043C(gene)|ensemblfungi:YCL043C_mRNA(transcript)|go:"GO:0003756"(protein disulfide isomerase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0006457"(protein folding)|go:"GO:0015035"(protein-disulfide reductase activity)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0036508"(protein alpha-1,2-demannosylation)|go:"GO:0051082"(unfolded protein binding)|go:"GO:1904382"(mannose trimming involved in glycoprotein ERAD pathway)|interpro:IPR005792(Protein disulphide isomerase)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR017937|interpro:IPR036249|rcsb pdb:2B5E|rcsb pdb:3BOA|reactome:R-SCE-901042 sgd:S000001247|refseq:NP_012074.3|dip:DIP-1890N|mint:P38888|ensemblfungi:YHR204W(gene)|ensemblfungi:YHR204W_mRNA(transcript)|go:"GO:0004571"(mannosyl-oligosaccharide 1,2-alpha-mannosidase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0016020"(membrane)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0036508"(protein alpha-1,2-demannosylation)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0097466"(ubiquitin-dependent glycoprotein ERAD pathway)|go:"GO:1904380"(endoplasmic reticulum mannose trimming)|go:"GO:1904382"(mannose trimming involved in glycoprotein ERAD pathway)|interpro:IPR001382(Glycoside hydrolase, family 47)|interpro:IPR012341(Six-hairpin glycosidase)|interpro:IPR036026|interpro:IPR044674 - crc64:69CF3E05D7F74C94 - figure legend:Fig. 6C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2017/09/05 2017/09/05 rogid:tyy52cf76yr9hl+9ggGGS4zDO/A559292 rogid:X8SFT/OIFa+RJWosZzSqkhDPMlo559292 rigid:JpQirWOQwpm9c+YQWbQIjAt1tnI false ha tag:?-? myc tag:c-c|necessary binding region:547-646 - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot)