#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P32639	uniprotkb:P33334	intact:EBI-861|uniprotkb:D3DM80|ensemblfungi:YER172C	intact:EBI-465|uniprotkb:D3DLB4|ensemblfungi:YHR165C	psi-mi:brr2_yeast(display_long)|uniprotkb:BRR2(gene name)|psi-mi:BRR2(display_short)|uniprotkb:RSS1(gene name synonym)|uniprotkb:SNU246(gene name synonym)|uniprotkb:YER172C(locus name)|uniprotkb:SYGP-ORF66(orf name)|uniprotkb:Protein Snu246(gene name synonym)	psi-mi:prp8_yeast(display_long)|uniprotkb:PRP8(gene name)|psi-mi:PRP8(display_short)|uniprotkb:DBF3(gene name synonym)|uniprotkb:DNA39(gene name synonym)|uniprotkb:RNA8(gene name synonym)|uniprotkb:SLT21(gene name synonym)|uniprotkb:USA2(gene name synonym)|uniprotkb:YHR165C(locus name)	psi-mi:"MI:0096"(pull down)	Maeder et al. (2009)	pubmed:19098916|doi:10.1038/nsmb.1535|imex:IM-14252	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15748070|imex:IM-14252-1|dip:DIP-9827E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_011099.1|sgd:S000000974|dip:DIP-850N|mint:P32639|ensemblfungi:YER172C(gene)|ensemblfungi:YER172C_mRNA(transcript)|go:"GO:0000388"("spliceosome conformational change to release U4 (or U4atac) and U1 (or U11)")|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005682"(U5 snRNP)|go:"GO:0042802"(identical protein binding)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR004179(Sec63)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR027417|interpro:IPR035892|interpro:IPR036388|interpro:IPR036390|interpro:IPR041094|rcsb pdb:3HIB|rcsb pdb:3IM1|rcsb pdb:3IM2|rcsb pdb:3JCM|rcsb pdb:4BGD|rcsb pdb:5DCA|rcsb pdb:5GAN|rcsb pdb:5GAO|rcsb pdb:5GAP|rcsb pdb:5GM6|rcsb pdb:5LJ5|rcsb pdb:5LQW|rcsb pdb:5M52|rcsb pdb:5M5P|rcsb pdb:5NRL|rcsb pdb:5ZWM|rcsb pdb:5ZWO|rcsb pdb:7B9V	refseq:NP_012035.1|sgd:S000001208|rcsb pdb:4ILJ|rcsb pdb:5DCA|rcsb pdb:5GAM|rcsb pdb:5GAN|rcsb pdb:5GAO|rcsb pdb:5GAP|rcsb pdb:5GM6|rcsb pdb:5GMK|rcsb pdb:5LJ3|rcsb pdb:5LJ5|rcsb pdb:5LQW|rcsb pdb:5M52|rcsb pdb:5M5P|rcsb pdb:5MPS|rcsb pdb:5MQ0|rcsb pdb:5NRL|rcsb pdb:5QY1|rcsb pdb:5QY2|rcsb pdb:5QY3|rcsb pdb:5QY4|rcsb pdb:5QY5|rcsb pdb:5QY6|rcsb pdb:5QY7|rcsb pdb:5QY8|rcsb pdb:5QY9|rcsb pdb:5QYA|rcsb pdb:5QYB|rcsb pdb:5QYC|rcsb pdb:5QYD|rcsb pdb:5QYE|rcsb pdb:5QYF|rcsb pdb:5QYG|rcsb pdb:5QYH|rcsb pdb:5QYI|rcsb pdb:5QYJ|rcsb pdb:5QYK|rcsb pdb:5QYL|rcsb pdb:5QYM|rcsb pdb:5QYN|rcsb pdb:5QYO|rcsb pdb:5QYP|rcsb pdb:5QYQ|rcsb pdb:5QYR|rcsb pdb:5QYS|rcsb pdb:5QYT|rcsb pdb:5QYU|rcsb pdb:5QYV|rcsb pdb:5QYW|rcsb pdb:5QYX|rcsb pdb:5QYY|rcsb pdb:5QYZ|rcsb pdb:5QZ0|rcsb pdb:5QZ1|rcsb pdb:5QZ2|rcsb pdb:5QZ3|rcsb pdb:5QZ4|rcsb pdb:5QZ5|rcsb pdb:5QZ6|rcsb pdb:5QZ7|rcsb pdb:5QZ8|rcsb pdb:5QZ9|rcsb pdb:5QZA|rcsb pdb:5QZB|rcsb pdb:5QZC|rcsb pdb:5QZD|rcsb pdb:5QZE|rcsb pdb:5QZF|rcsb pdb:5QZG|rcsb pdb:5QZH|rcsb pdb:5QZI|rcsb pdb:5QZJ|rcsb pdb:5QZK|rcsb pdb:5QZL|rcsb pdb:5QZM|rcsb pdb:5QZN|rcsb pdb:5QZO|rcsb pdb:5QZP|rcsb pdb:5R14|rcsb pdb:5R15|rcsb pdb:5R16|rcsb pdb:5R17|rcsb pdb:5R18|rcsb pdb:5R19|rcsb pdb:5R1A|rcsb pdb:5R1B|rcsb pdb:5R1C|rcsb pdb:5R1D|rcsb pdb:5R1E|rcsb pdb:5R1F|rcsb pdb:5R1G|rcsb pdb:5R1H|rcsb pdb:5R1I|rcsb pdb:5R1J|rcsb pdb:5R1K|rcsb pdb:5R1L|rcsb pdb:5R1M|rcsb pdb:5R1N|rcsb pdb:5R1O|rcsb pdb:5R1P|rcsb pdb:5R1Q|rcsb pdb:5R1S|rcsb pdb:5WSG|rcsb pdb:5Y88|rcsb pdb:5YLZ|rcsb pdb:5ZWM|rcsb pdb:5ZWO|rcsb pdb:6BK8|rcsb pdb:6EXN|rcsb pdb:6J6G|rcsb pdb:6J6H|rcsb pdb:6J6N|rcsb pdb:6J6Q|rcsb pdb:6TEO|rcsb pdb:7B9V|rcsb pdb:5QZQ|rcsb pdb:5QZR|rcsb pdb:5QZS|rcsb pdb:5QZT|rcsb pdb:5QZU|rcsb pdb:5QZV|rcsb pdb:5QZW|rcsb pdb:5QZX|rcsb pdb:5QZY|rcsb pdb:5QZZ|rcsb pdb:5R00|rcsb pdb:5R01|rcsb pdb:5R02|rcsb pdb:5R03|rcsb pdb:5R04|rcsb pdb:5R05|rcsb pdb:5R06|rcsb pdb:5R07|rcsb pdb:5R08|rcsb pdb:5R09|rcsb pdb:5R0A|rcsb pdb:5R0B|rcsb pdb:5R0C|rcsb pdb:5R0D|rcsb pdb:5R0E|rcsb pdb:5R0F|rcsb pdb:5R0G|rcsb pdb:5R0H|rcsb pdb:5R0I|rcsb pdb:5R0J|rcsb pdb:5R0K|rcsb pdb:5R0L|rcsb pdb:5R0M|rcsb pdb:5R0N|rcsb pdb:5R0O|rcsb pdb:5R0P|rcsb pdb:5R0Q|rcsb pdb:5R0R|rcsb pdb:5R0S|rcsb pdb:5R0T|rcsb pdb:5R0U|rcsb pdb:5R0V|rcsb pdb:5R0W|rcsb pdb:5R0X|rcsb pdb:5R0Y|rcsb pdb:5R0Z|rcsb pdb:5R10|rcsb pdb:5R11|rcsb pdb:5R12|rcsb pdb:5R13|ensemblfungi:YHR165C(gene)|ensemblfungi:YHR165C_mRNA(transcript)|go:"GO:0000244"(spliceosomal tri-snRNP complex assembly)|go:"GO:0000350"(generation of catalytic spliceosome for second transesterification step)|go:"GO:0000389"(mRNA 3'-splice site recognition)|go:"GO:0000395"(mRNA 5'-splice site recognition)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005682"(U5 snRNP)|go:"GO:0008237"(metallopeptidase activity)|go:"GO:0017070"(U6 snRNA binding)|go:"GO:0030619"(U1 snRNA binding)|go:"GO:0030620"(U2 snRNA binding)|go:"GO:0030623"(U5 snRNA binding)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0070122"(isopeptidase activity)|go:"GO:0071013"(catalytic step 2 spliceosome)|rcsb pdb:3SBT|rcsb pdb:3ZEF|rcsb pdb:4BGD|rcsb pdb:4I43|go:"GO:0097157"(pre-mRNA intronic binding)|interpro:IPR000555(Mov34/MPN/PAD-1)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR012591(PRO8NT)|interpro:IPR012592(PROCN)|interpro:IPR012984(PRO, C-terminal)|interpro:IPR019580|interpro:IPR019581|interpro:IPR019582|interpro:IPR021983|interpro:IPR027652|interpro:IPR037518|interpro:IPR042516|interpro:IPR043172|interpro:IPR043173|rcsb pdb:2OG4|rcsb pdb:3E66|rcsb pdb:3E9O|rcsb pdb:3E9P|rcsb pdb:3JCM|rcsb pdb:3SBG|rcsb pdb:4ILG|rcsb pdb:4ILH|dip:DIP-2427N|mint:P33334	psi-mi:"MI:0465"(dip)	crc64:DFAF7E3B7168D944	crc64:8F4F6F89D34D3508	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/06	2017/08/10	rogid:2bNoVkou3QatkNCtPIiSdvPdgEo559292	rogid:0JoVp7ULlbib7N5+GOPksHStSmY559292	rigid:LTmk/09ibUUTtDosYZDxdXup6h0	false	calmodulin binding protein tag:c-c	binding-associated region:1806-2413|mutation disrupting interaction strength:2387-2387|mutation disrupting interaction strength:2388-2388|glutathione s tranferase tag:n-n|mutation disrupting interaction strength:2387-2387|mutation disrupting interaction strength:2388-2388	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)