#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P61970 uniprotkb:P61970 intact:EBI-591778|uniprotkb:P13662|uniprotkb:Q6IB67|uniprotkb:B2R4G7|ensembl:ENSP00000219169|ensembl:ENSP00000457022|ensembl:ENSP00000457989 intact:EBI-591778|uniprotkb:P13662|uniprotkb:Q6IB67|uniprotkb:B2R4G7|ensembl:ENSP00000219169|ensembl:ENSP00000457022|ensembl:ENSP00000457989 psi-mi:ntf2_human(display_long)|uniprotkb:Placental protein 15(gene name synonym)|uniprotkb:NUTF2(gene name)|psi-mi:NUTF2(display_short)|uniprotkb:NTF2(gene name synonym) psi-mi:ntf2_human(display_long)|uniprotkb:Placental protein 15(gene name synonym)|uniprotkb:NUTF2(gene name)|psi-mi:NUTF2(display_short)|uniprotkb:NTF2(gene name synonym) psi-mi:"MI:0071"(molecular sieving) Jovanovic-Talisman et al. (2009) pubmed:19098896|doi:10.1038/nature07600|imex:IM-17852 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15747816|imex:IM-17852-1|dip:DIP-44982E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005787.1|refseq:NP_001308967.1|refseq:NP_001308968.1|refseq:NP_001308969.1|refseq:NP_001308970.1|dip:DIP-6057N|ensembl:ENSG00000102898(gene)|ensembl:ENST00000219169(transcript)|ensembl:ENST00000568396(transcript)|ensembl:ENST00000569436(transcript)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0044613"(nuclear pore central transport channel)|go:"GO:0051028"(mRNA transport)|go:"GO:0061608"(nuclear import signal receptor activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090204"(protein localization to nuclear pore)|go:"GO:1904046"(negative regulation of vascular endothelial growth factor production)|interpro:IPR002075(Nuclear transport factor 2)|interpro:IPR018222|interpro:IPR032710|rcsb pdb:1GY5 refseq:NP_005787.1|refseq:NP_001308967.1|refseq:NP_001308968.1|refseq:NP_001308969.1|refseq:NP_001308970.1|dip:DIP-6057N|ensembl:ENSG00000102898(gene)|ensembl:ENST00000219169(transcript)|ensembl:ENST00000568396(transcript)|ensembl:ENST00000569436(transcript)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0044613"(nuclear pore central transport channel)|go:"GO:0051028"(mRNA transport)|go:"GO:0061608"(nuclear import signal receptor activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090204"(protein localization to nuclear pore)|go:"GO:1904046"(negative regulation of vascular endothelial growth factor production)|interpro:IPR002075(Nuclear transport factor 2)|interpro:IPR018222|interpro:IPR032710|rcsb pdb:1GY5 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/06 2017/08/10 rogid:hDy30rHCK1a4LjUfAWtf1DEu8n89606 rogid:hDy30rHCK1a4LjUfAWtf1DEu8n89606 rigid:QZqhDU/A/q/ax9JxW4N55fWFcys false - - - 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q06142 uniprotkb:P14907 intact:EBI-9145|ensemblfungi:YLR347C|uniprotkb:D6VYY6 intact:EBI-12265|uniprotkb:D6VWE3 psi-mi:imb1_yeast(display_long)|uniprotkb:KAP95(gene name)|psi-mi:KAP95(display_short)|uniprotkb:YLR347C(locus name)|uniprotkb:L8300.15(orf name)|uniprotkb:Karyopherin subunit beta-1(gene name synonym)|uniprotkb:Karyopherin-95(gene name synonym)|uniprotkb:Importin-95(gene name synonym) psi-mi:nsp1_yeast(display_long)|uniprotkb:NSP1(gene name)|psi-mi:NSP1(display_short)|uniprotkb:YJL041W(locus name)|uniprotkb:J1207(orf name)|uniprotkb:Nuclear pore protein NSP1(gene name synonym)|uniprotkb:Nucleoskeletal-like protein(gene name synonym)|uniprotkb:p110(gene name synonym) psi-mi:"MI:0047"(far western blotting) Jovanovic-Talisman et al. (2009) pubmed:19098896|doi:10.1038/nature07600|imex:IM-17852 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15747849|imex:IM-17852-3|dip:DIP-66960E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:3EA5|rcsb pdb:3ND2|rcsb pdb:5OWU|reactome:R-SCE-2995383|reactome:R-SCE-6798695|ensemblfungi:YLR347C(gene)|ensemblfungi:YLR347C_mRNA(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0006656"(phosphatidylcholine biosynthetic process)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0042564"(NLS-dependent protein nuclear import complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046822"(regulation of nucleocytoplasmic transport)|go:"GO:0051028"(mRNA transport)|go:"GO:0051292"(nuclear pore complex assembly)|go:"GO:0060188"(regulation of protein desumoylation)|go:"GO:0061608"(nuclear import signal receptor activity)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0097718"(disordered domain specific binding)|interpro:IPR000225(Armadillo)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR040122|rcsb pdb:2BKU|go:"GO:0006612"(protein targeting to membrane)|refseq:NP_013451.1|sgd:S000004339|dip:DIP-2357N|mint:Q06142 go:"GO:0000055"(ribosomal large subunit export from nucleus)|go:"GO:0000056"(ribosomal small subunit export from nucleus)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005643"(nuclear pore)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006409"(tRNA export from nucleus)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0007049"(cell cycle)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034399"(nuclear periphery)|go:"GO:0044613"(nuclear pore central transport channel)|go:"GO:0044615"(nuclear pore nuclear basket)|go:"GO:0097064"(ncRNA export from nucleus)|interpro:IPR007758(Nucleoporin, Nsp1-like, C-terminal)|interpro:IPR026010|rcsb pdb:1O6O|refseq:NP_012494.3|sgd:S000003577|mint:P14907|dip:DIP-1484N psi-mi:"MI:0465"(dip) crc64:ED530F5313E75B06 crc64:A258003CB1917810 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/06 2017/08/10 rogid:ebWeXaUKiBFWgjdv9s2pz1GIqgI559292 rogid:wFdC6D8JzkhJpF+k3qtnFj9+4pA559292 rigid:5oMfdzHLfHBb38f/v2CsaTRi94I false alexa 488 label:?-? binding-associated region:30-591 - - psi-mi:"MI:0867"(tag visualisation by fluorescence) psi-mi:"MI:0867"(tag visualisation by fluorescence) uniprotkb:P62826 uniprotkb:P61970 intact:EBI-286642|uniprotkb:P17080|uniprotkb:P28746|uniprotkb:P28747|uniprotkb:Q6IPB2|uniprotkb:Q86V08|uniprotkb:Q8NI90|uniprotkb:Q9CZA2|uniprotkb:Q9CSP3|uniprotkb:Q9CWI7|uniprotkb:Q9UDJ5|uniprotkb:Q9UEU9|uniprotkb:A8K3Z8|ensembl:ENSP00000376176|ensembl:ENSP00000446215 intact:EBI-591778|uniprotkb:P13662|uniprotkb:Q6IB67|uniprotkb:B2R4G7|ensembl:ENSP00000219169|ensembl:ENSP00000457022|ensembl:ENSP00000457989 psi-mi:ran_human(display_long)|uniprotkb:GTPase Ran(gene name synonym)|uniprotkb:Ras-related nuclear protein(gene name synonym)|uniprotkb:Ras-like protein TC4(gene name synonym)|uniprotkb:Androgen receptor-associated protein 24(gene name synonym)|uniprotkb:RAN(gene name)|psi-mi:RAN(display_short)|uniprotkb:ARA24(gene name synonym)|uniprotkb:OK/SW-cl.81(orf name) psi-mi:ntf2_human(display_long)|uniprotkb:Placental protein 15(gene name synonym)|uniprotkb:NUTF2(gene name)|psi-mi:NUTF2(display_short)|uniprotkb:NTF2(gene name synonym) psi-mi:"MI:0404"(comigration in non denaturing gel electrophoresis) Jovanovic-Talisman et al. (2009) pubmed:19098896|doi:10.1038/nature07600|imex:IM-17852 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15747832|imex:IM-17852-2|dip:DIP-44981E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006316.1|refseq:NP_001287725.1|refseq:NP_001287726.1|dip:DIP-5929N|ensembl:ENSG00000132341(gene)|ensembl:ENST00000392369(transcript)|ensembl:ENST00000543796(transcript)|go:"GO:0000054"(ribosomal subunit export from nucleus)|go:"GO:0000055"(ribosomal large subunit export from nucleus)|go:"GO:0000056"(ribosomal small subunit export from nucleus)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0006259"(DNA metabolic process)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0016020"(membrane)|go:"GO:0016032"(viral process)|go:"GO:0019003"(GDP binding)|go:"GO:0030496"(midbody)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035281"(pre-miRNA export from nucleus)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042470"(melanosome)|go:"GO:0042565"(RNA nuclear export complex)|go:"GO:0045296"(cadherin binding)|go:"GO:0046039"(GTP metabolic process)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051301"(cell division)|go:"GO:0055037"(recycling endosome)|go:"GO:0061015"(snRNA import into nucleus)|go:"GO:0070062"(extracellular exosome)|go:"GO:1902570"(protein localization to nucleolus)|interpro:IPR001806(Ras GTPase)|interpro:IPR002041(Ran GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|mint:P62826|rcsb pdb:1I2M|rcsb pdb:1IBR|rcsb pdb:1K5D|rcsb pdb:1K5G|rcsb pdb:1QBK|rcsb pdb:1RRP|rcsb pdb:2MMC|rcsb pdb:2MMG|rcsb pdb:2N1B|rcsb pdb:3CH5|rcsb pdb:3EA5|rcsb pdb:3GJ0|rcsb pdb:3GJ3|rcsb pdb:3GJ4|rcsb pdb:3GJ5|rcsb pdb:3GJ6|rcsb pdb:3GJ7|rcsb pdb:3GJ8|rcsb pdb:3GJX|rcsb pdb:3NBY|rcsb pdb:3NBZ|rcsb pdb:3NC0|rcsb pdb:3NC1|rcsb pdb:3ZJY|rcsb pdb:4C0Q|rcsb pdb:4GMX|rcsb pdb:4GPT|rcsb pdb:4HAT|rcsb pdb:4HAU|rcsb pdb:4HAV|rcsb pdb:4HAW|rcsb pdb:4HAX|rcsb pdb:4HAY|rcsb pdb:4HAZ|rcsb pdb:4HB0|rcsb pdb:4HB2|rcsb pdb:4HB3|rcsb pdb:4HB4|rcsb pdb:4OL0|rcsb pdb:4WVF|rcsb pdb:5CIQ|rcsb pdb:5CIT|rcsb pdb:5CIW|rcsb pdb:5CJ2|rcsb pdb:5CLL|rcsb pdb:5CLQ|rcsb pdb:5DH9|rcsb pdb:5DHA|rcsb pdb:5DHF|rcsb pdb:5DI9|rcsb pdb:5DIF|rcsb pdb:5DIS|rcsb pdb:5DLQ|rcsb pdb:5FYQ|rcsb pdb:5JLJ|rcsb pdb:5UWH|rcsb pdb:5UWI|rcsb pdb:5UWJ|rcsb pdb:5UWO|rcsb pdb:5UWP|rcsb pdb:5UWQ|rcsb pdb:5UWR|rcsb pdb:5UWS|rcsb pdb:5UWT|rcsb pdb:5UWU|rcsb pdb:5UWW|rcsb pdb:5YRO|rcsb pdb:5YST|rcsb pdb:5YSU|rcsb pdb:5YTB|rcsb pdb:5ZPU|rcsb pdb:6A38|rcsb pdb:6A3A|rcsb pdb:6A3B|rcsb pdb:6A3C|rcsb pdb:6A3E|rcsb pdb:6CIT|rcsb pdb:6KFT|rcsb pdb:6LQ9|rcsb pdb:6M60|rcsb pdb:6M6X|rcsb pdb:6Q82|rcsb pdb:6Q84|rcsb pdb:6TVO|rcsb pdb:6X2M|rcsb pdb:6X2O|rcsb pdb:6X2P|rcsb pdb:6X2R|rcsb pdb:6X2S|rcsb pdb:6X2U|rcsb pdb:6X2V|rcsb pdb:6X2W|rcsb pdb:6X2X|rcsb pdb:6X2Y|rcsb pdb:6XJP|rcsb pdb:6XJR|rcsb pdb:6XJS|rcsb pdb:6XJT|rcsb pdb:6XJU|rcsb pdb:7B51|rcsb pdb:7CND|rcsb pdb:7L5E|reactome:R-HSA-165054|reactome:R-HSA-1655829|reactome:R-HSA-168333|reactome:R-HSA-180746|reactome:R-HSA-203927|reactome:R-HSA-5578749|reactome:R-HSA-6784531|reactome:R-HSA-9615933 refseq:NP_005787.1|refseq:NP_001308967.1|refseq:NP_001308968.1|refseq:NP_001308969.1|refseq:NP_001308970.1|dip:DIP-6057N|ensembl:ENSG00000102898(gene)|ensembl:ENST00000219169(transcript)|ensembl:ENST00000568396(transcript)|ensembl:ENST00000569436(transcript)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0044613"(nuclear pore central transport channel)|go:"GO:0051028"(mRNA transport)|go:"GO:0061608"(nuclear import signal receptor activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090204"(protein localization to nuclear pore)|go:"GO:1904046"(negative regulation of vascular endothelial growth factor production)|interpro:IPR002075(Nuclear transport factor 2)|interpro:IPR018222|interpro:IPR032710|rcsb pdb:1GY5 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/06 2017/08/10 rogid:trIUv5n3nI5d0rkfDTgw/6ubxMA9606 rogid:hDy30rHCK1a4LjUfAWtf1DEu8n89606 rigid:MkY6oq0EuQkDzJwGbhA2CJ0dH34 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P61970 uniprotkb:P61970 intact:EBI-591778|uniprotkb:P13662|uniprotkb:Q6IB67|uniprotkb:B2R4G7|ensembl:ENSP00000219169|ensembl:ENSP00000457022|ensembl:ENSP00000457989 intact:EBI-591778|uniprotkb:P13662|uniprotkb:Q6IB67|uniprotkb:B2R4G7|ensembl:ENSP00000219169|ensembl:ENSP00000457022|ensembl:ENSP00000457989 psi-mi:ntf2_human(display_long)|uniprotkb:Placental protein 15(gene name synonym)|uniprotkb:NUTF2(gene name)|psi-mi:NUTF2(display_short)|uniprotkb:NTF2(gene name synonym) psi-mi:ntf2_human(display_long)|uniprotkb:Placental protein 15(gene name synonym)|uniprotkb:NUTF2(gene name)|psi-mi:NUTF2(display_short)|uniprotkb:NTF2(gene name synonym) psi-mi:"MI:0404"(comigration in non denaturing gel electrophoresis) Jovanovic-Talisman et al. (2009) pubmed:19098896|doi:10.1038/nature07600|imex:IM-17852 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15747870|imex:IM-17852-4|dip:DIP-44982E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005787.1|refseq:NP_001308967.1|refseq:NP_001308968.1|refseq:NP_001308969.1|refseq:NP_001308970.1|dip:DIP-6057N|ensembl:ENSG00000102898(gene)|ensembl:ENST00000219169(transcript)|ensembl:ENST00000568396(transcript)|ensembl:ENST00000569436(transcript)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0044613"(nuclear pore central transport channel)|go:"GO:0051028"(mRNA transport)|go:"GO:0061608"(nuclear import signal receptor activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090204"(protein localization to nuclear pore)|go:"GO:1904046"(negative regulation of vascular endothelial growth factor production)|interpro:IPR002075(Nuclear transport factor 2)|interpro:IPR018222|interpro:IPR032710|rcsb pdb:1GY5 refseq:NP_005787.1|refseq:NP_001308967.1|refseq:NP_001308968.1|refseq:NP_001308969.1|refseq:NP_001308970.1|dip:DIP-6057N|ensembl:ENSG00000102898(gene)|ensembl:ENST00000219169(transcript)|ensembl:ENST00000568396(transcript)|ensembl:ENST00000569436(transcript)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0044613"(nuclear pore central transport channel)|go:"GO:0051028"(mRNA transport)|go:"GO:0061608"(nuclear import signal receptor activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090204"(protein localization to nuclear pore)|go:"GO:1904046"(negative regulation of vascular endothelial growth factor production)|interpro:IPR002075(Nuclear transport factor 2)|interpro:IPR018222|interpro:IPR032710|rcsb pdb:1GY5 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/06 2017/08/10 rogid:hDy30rHCK1a4LjUfAWtf1DEu8n89606 rogid:hDy30rHCK1a4LjUfAWtf1DEu8n89606 rigid:QZqhDU/A/q/ax9JxW4N55fWFcys false - - - 0 psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:Q02629 uniprotkb:Q06142 intact:EBI-11698|ensemblfungi:YKL068W|uniprotkb:D6VXL9 intact:EBI-9145|ensemblfungi:YLR347C|uniprotkb:D6VYY6 psi-mi:nu100_yeast(display_long)|uniprotkb:NUP100(gene name)|psi-mi:NUP100(display_short)|uniprotkb:NSP100(gene name synonym)|uniprotkb:YKL068W(locus name)|uniprotkb:YKL336(orf name)|uniprotkb:Nuclear pore protein NUP100/NSP100(gene name synonym) psi-mi:imb1_yeast(display_long)|uniprotkb:KAP95(gene name)|psi-mi:KAP95(display_short)|uniprotkb:YLR347C(locus name)|uniprotkb:L8300.15(orf name)|uniprotkb:Karyopherin subunit beta-1(gene name synonym)|uniprotkb:Karyopherin-95(gene name synonym)|uniprotkb:Importin-95(gene name synonym) psi-mi:"MI:0047"(far western blotting) Jovanovic-Talisman et al. (2009) pubmed:19098896|doi:10.1038/nature07600|imex:IM-17852 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15747886|imex:IM-17852-5|dip:DIP-2846E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YKL068W(gene)|ensemblfungi:YKL068W_mRNA(transcript)|go:"GO:0000973"(posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031965"(nuclear membrane)|go:"GO:0005643"(nuclear pore)|go:"GO:0031990"(mRNA export from nucleus in response to heat stress)|go:"GO:0036228"(protein localization to nuclear inner membrane)|go:"GO:0044613"(nuclear pore central transport channel)|go:"GO:0044614"(nuclear pore cytoplasmic filaments)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR007230(Peptidase S59, nucleoporin)|interpro:IPR025574|interpro:IPR036903|interpro:IPR037637|interpro:IPR037665|refseq:NP_012855.1|sgd:S000001551|mint:Q02629|dip:DIP-2351N rcsb pdb:3EA5|rcsb pdb:3ND2|rcsb pdb:5OWU|reactome:R-SCE-2995383|reactome:R-SCE-6798695|ensemblfungi:YLR347C(gene)|ensemblfungi:YLR347C_mRNA(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0006656"(phosphatidylcholine biosynthetic process)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0042564"(NLS-dependent protein nuclear import complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046822"(regulation of nucleocytoplasmic transport)|go:"GO:0051028"(mRNA transport)|go:"GO:0051292"(nuclear pore complex assembly)|go:"GO:0060188"(regulation of protein desumoylation)|go:"GO:0061608"(nuclear import signal receptor activity)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0097718"(disordered domain specific binding)|interpro:IPR000225(Armadillo)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR040122|rcsb pdb:2BKU|go:"GO:0006612"(protein targeting to membrane)|refseq:NP_013451.1|sgd:S000004339|dip:DIP-2357N|mint:Q06142 psi-mi:"MI:0465"(dip) crc64:D3985F9901BBAA51 crc64:ED530F5313E75B06 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/06 2017/08/10 rogid:cdG/6Bz1Q30Of8KHqHp7FGTaOR8559292 rogid:ebWeXaUKiBFWgjdv9s2pz1GIqgI559292 rigid:IdzBoP+vCxDiWX/lY+Tihqcr/Nk false binding-associated region:1-570 alexa 488 label:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q02821 uniprotkb:Q06142 intact:EBI-1797|uniprotkb:D6W0Z8|ensemblfungi:YNL189W intact:EBI-9145|ensemblfungi:YLR347C|uniprotkb:D6VYY6 psi-mi:ima1_yeast(display_long)|uniprotkb:SRP1(gene name)|psi-mi:SRP1(display_short)|uniprotkb:KAP60(gene name synonym)|uniprotkb:YNL189W(locus name)|uniprotkb:N1606(orf name)|uniprotkb:Karyopherin subunit alpha(gene name synonym)|uniprotkb:Karyopherin-60(gene name synonym)|uniprotkb:Serine-rich RNA polymerase I suppressor protein(gene name synonym) psi-mi:imb1_yeast(display_long)|uniprotkb:KAP95(gene name)|psi-mi:KAP95(display_short)|uniprotkb:YLR347C(locus name)|uniprotkb:L8300.15(orf name)|uniprotkb:Karyopherin subunit beta-1(gene name synonym)|uniprotkb:Karyopherin-95(gene name synonym)|uniprotkb:Importin-95(gene name synonym) psi-mi:"MI:0404"(comigration in non denaturing gel electrophoresis) Jovanovic-Talisman et al. (2009) pubmed:19098896|doi:10.1038/nature07600|imex:IM-17852 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15747907|imex:IM-17852-6|dip:DIP-10839E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014210.1|sgd:S000005133|dip:DIP-728N|mint:Q02821|ensemblfungi:YNL189W(gene)|ensemblfungi:YNL189W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0031144"(proteasome localization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042564"(NLS-dependent protein nuclear import complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0061608"(nuclear import signal receptor activity)|go:"GO:0097718"(disordered domain specific binding)|interpro:IPR000225(Armadillo)|interpro:IPR002652(Importin-alpha-like, importin-beta-binding region)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR024931|interpro:IPR032413|interpro:IPR036975|rcsb pdb:1BK5|rcsb pdb:1BK6|rcsb pdb:1EE4|rcsb pdb:1EE5|rcsb pdb:1UN0|rcsb pdb:1WA5|rcsb pdb:2C1T|rcsb pdb:4PVZ|rcsb pdb:4XZR|rcsb pdb:5H2W|rcsb pdb:5H2X|rcsb pdb:5T94 rcsb pdb:3EA5|rcsb pdb:3ND2|rcsb pdb:5OWU|reactome:R-SCE-2995383|reactome:R-SCE-6798695|ensemblfungi:YLR347C(gene)|ensemblfungi:YLR347C_mRNA(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0006656"(phosphatidylcholine biosynthetic process)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0042564"(NLS-dependent protein nuclear import complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046822"(regulation of nucleocytoplasmic transport)|go:"GO:0051028"(mRNA transport)|go:"GO:0051292"(nuclear pore complex assembly)|go:"GO:0060188"(regulation of protein desumoylation)|go:"GO:0061608"(nuclear import signal receptor activity)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0097718"(disordered domain specific binding)|interpro:IPR000225(Armadillo)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR040122|rcsb pdb:2BKU|go:"GO:0006612"(protein targeting to membrane)|refseq:NP_013451.1|sgd:S000004339|dip:DIP-2357N|mint:Q06142 psi-mi:"MI:0465"(dip) crc64:8D3A0CB76F2E7C00 crc64:ED530F5313E75B06 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/06 2017/08/10 rogid:NyzC93xnBCb8DX/AH346lwg4u2A559292 rogid:ebWeXaUKiBFWgjdv9s2pz1GIqgI559292 rigid:4FGS69xwwNJvFc6wNxkSjq1hb9M false binding-associated region:1-65|enhanced green fluorescent protein tag:c-c - - - psi-mi:"MI:0867"(tag visualisation by fluorescence) psi-mi:"MI:0867"(tag visualisation by fluorescence) uniprotkb:Q02629 uniprotkb:Q06142 intact:EBI-11698|ensemblfungi:YKL068W|uniprotkb:D6VXL9 intact:EBI-9145|ensemblfungi:YLR347C|uniprotkb:D6VYY6 psi-mi:nu100_yeast(display_long)|uniprotkb:NUP100(gene name)|psi-mi:NUP100(display_short)|uniprotkb:NSP100(gene name synonym)|uniprotkb:YKL068W(locus name)|uniprotkb:YKL336(orf name)|uniprotkb:Nuclear pore protein NUP100/NSP100(gene name synonym) psi-mi:imb1_yeast(display_long)|uniprotkb:KAP95(gene name)|psi-mi:KAP95(display_short)|uniprotkb:YLR347C(locus name)|uniprotkb:L8300.15(orf name)|uniprotkb:Karyopherin subunit beta-1(gene name synonym)|uniprotkb:Karyopherin-95(gene name synonym)|uniprotkb:Importin-95(gene name synonym) psi-mi:"MI:0096"(pull down) Jovanovic-Talisman et al. (2009) pubmed:19098896|doi:10.1038/nature07600|imex:IM-17852 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15747968|imex:IM-17852-9|dip:DIP-2846E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YKL068W(gene)|ensemblfungi:YKL068W_mRNA(transcript)|go:"GO:0000973"(posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031965"(nuclear membrane)|go:"GO:0005643"(nuclear pore)|go:"GO:0031990"(mRNA export from nucleus in response to heat stress)|go:"GO:0036228"(protein localization to nuclear inner membrane)|go:"GO:0044613"(nuclear pore central transport channel)|go:"GO:0044614"(nuclear pore cytoplasmic filaments)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR007230(Peptidase S59, nucleoporin)|interpro:IPR025574|interpro:IPR036903|interpro:IPR037637|interpro:IPR037665|refseq:NP_012855.1|sgd:S000001551|mint:Q02629|dip:DIP-2351N rcsb pdb:3EA5|rcsb pdb:3ND2|rcsb pdb:5OWU|reactome:R-SCE-2995383|reactome:R-SCE-6798695|ensemblfungi:YLR347C(gene)|ensemblfungi:YLR347C_mRNA(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0006656"(phosphatidylcholine biosynthetic process)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0042564"(NLS-dependent protein nuclear import complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046822"(regulation of nucleocytoplasmic transport)|go:"GO:0051028"(mRNA transport)|go:"GO:0051292"(nuclear pore complex assembly)|go:"GO:0060188"(regulation of protein desumoylation)|go:"GO:0061608"(nuclear import signal receptor activity)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0097718"(disordered domain specific binding)|interpro:IPR000225(Armadillo)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR040122|rcsb pdb:2BKU|go:"GO:0006612"(protein targeting to membrane)|refseq:NP_013451.1|sgd:S000004339|dip:DIP-2357N|mint:Q06142 psi-mi:"MI:0465"(dip) crc64:D3985F9901BBAA51 crc64:ED530F5313E75B06 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/06 2017/08/10 rogid:cdG/6Bz1Q30Of8KHqHp7FGTaOR8559292 rogid:ebWeXaUKiBFWgjdv9s2pz1GIqgI559292 rigid:IdzBoP+vCxDiWX/lY+Tihqcr/Nk false binding-associated region:1-570|his tag:n-n - - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:Q02629 uniprotkb:P61970 intact:EBI-11698|ensemblfungi:YKL068W|uniprotkb:D6VXL9 intact:EBI-591778|uniprotkb:P13662|uniprotkb:Q6IB67|uniprotkb:B2R4G7|ensembl:ENSP00000219169|ensembl:ENSP00000457022|ensembl:ENSP00000457989 psi-mi:nu100_yeast(display_long)|uniprotkb:NUP100(gene name)|psi-mi:NUP100(display_short)|uniprotkb:NSP100(gene name synonym)|uniprotkb:YKL068W(locus name)|uniprotkb:YKL336(orf name)|uniprotkb:Nuclear pore protein NUP100/NSP100(gene name synonym) psi-mi:ntf2_human(display_long)|uniprotkb:Placental protein 15(gene name synonym)|uniprotkb:NUTF2(gene name)|psi-mi:NUTF2(display_short)|uniprotkb:NTF2(gene name synonym) psi-mi:"MI:0047"(far western blotting) Jovanovic-Talisman et al. (2009) pubmed:19098896|doi:10.1038/nature07600|imex:IM-17852 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15747947|imex:IM-17852-8|dip:DIP-189299E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YKL068W(gene)|ensemblfungi:YKL068W_mRNA(transcript)|go:"GO:0000973"(posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031965"(nuclear membrane)|go:"GO:0005643"(nuclear pore)|go:"GO:0031990"(mRNA export from nucleus in response to heat stress)|go:"GO:0036228"(protein localization to nuclear inner membrane)|go:"GO:0044613"(nuclear pore central transport channel)|go:"GO:0044614"(nuclear pore cytoplasmic filaments)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR007230(Peptidase S59, nucleoporin)|interpro:IPR025574|interpro:IPR036903|interpro:IPR037637|interpro:IPR037665|refseq:NP_012855.1|sgd:S000001551|mint:Q02629|dip:DIP-2351N refseq:NP_005787.1|refseq:NP_001308967.1|refseq:NP_001308968.1|refseq:NP_001308969.1|refseq:NP_001308970.1|dip:DIP-6057N|ensembl:ENSG00000102898(gene)|ensembl:ENST00000219169(transcript)|ensembl:ENST00000568396(transcript)|ensembl:ENST00000569436(transcript)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0044613"(nuclear pore central transport channel)|go:"GO:0051028"(mRNA transport)|go:"GO:0061608"(nuclear import signal receptor activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090204"(protein localization to nuclear pore)|go:"GO:1904046"(negative regulation of vascular endothelial growth factor production)|interpro:IPR002075(Nuclear transport factor 2)|interpro:IPR018222|interpro:IPR032710|rcsb pdb:1GY5 psi-mi:"MI:0465"(dip) crc64:D3985F9901BBAA51 - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/06 2017/08/10 rogid:cdG/6Bz1Q30Of8KHqHp7FGTaOR8559292 rogid:hDy30rHCK1a4LjUfAWtf1DEu8n89606 rigid:ykM3o9A2myAAGYc5FXjXdsGz+NQ false binding-associated region:1-570 yellow fluorescent protein tag:c-c - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q02821 uniprotkb:Q06142 intact:EBI-1797|uniprotkb:D6W0Z8|ensemblfungi:YNL189W intact:EBI-9145|ensemblfungi:YLR347C|uniprotkb:D6VYY6 psi-mi:ima1_yeast(display_long)|uniprotkb:SRP1(gene name)|psi-mi:SRP1(display_short)|uniprotkb:KAP60(gene name synonym)|uniprotkb:YNL189W(locus name)|uniprotkb:N1606(orf name)|uniprotkb:Karyopherin subunit alpha(gene name synonym)|uniprotkb:Karyopherin-60(gene name synonym)|uniprotkb:Serine-rich RNA polymerase I suppressor protein(gene name synonym) psi-mi:imb1_yeast(display_long)|uniprotkb:KAP95(gene name)|psi-mi:KAP95(display_short)|uniprotkb:YLR347C(locus name)|uniprotkb:L8300.15(orf name)|uniprotkb:Karyopherin subunit beta-1(gene name synonym)|uniprotkb:Karyopherin-95(gene name synonym)|uniprotkb:Importin-95(gene name synonym) psi-mi:"MI:0071"(molecular sieving) Jovanovic-Talisman et al. (2009) pubmed:19098896|doi:10.1038/nature07600|imex:IM-17852 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15747928|imex:IM-17852-7|dip:DIP-10839E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014210.1|sgd:S000005133|dip:DIP-728N|mint:Q02821|ensemblfungi:YNL189W(gene)|ensemblfungi:YNL189W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0031144"(proteasome localization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042564"(NLS-dependent protein nuclear import complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0061608"(nuclear import signal receptor activity)|go:"GO:0097718"(disordered domain specific binding)|interpro:IPR000225(Armadillo)|interpro:IPR002652(Importin-alpha-like, importin-beta-binding region)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR024931|interpro:IPR032413|interpro:IPR036975|rcsb pdb:1BK5|rcsb pdb:1BK6|rcsb pdb:1EE4|rcsb pdb:1EE5|rcsb pdb:1UN0|rcsb pdb:1WA5|rcsb pdb:2C1T|rcsb pdb:4PVZ|rcsb pdb:4XZR|rcsb pdb:5H2W|rcsb pdb:5H2X|rcsb pdb:5T94 rcsb pdb:3EA5|rcsb pdb:3ND2|rcsb pdb:5OWU|reactome:R-SCE-2995383|reactome:R-SCE-6798695|ensemblfungi:YLR347C(gene)|ensemblfungi:YLR347C_mRNA(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0006656"(phosphatidylcholine biosynthetic process)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0042564"(NLS-dependent protein nuclear import complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046822"(regulation of nucleocytoplasmic transport)|go:"GO:0051028"(mRNA transport)|go:"GO:0051292"(nuclear pore complex assembly)|go:"GO:0060188"(regulation of protein desumoylation)|go:"GO:0061608"(nuclear import signal receptor activity)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0097718"(disordered domain specific binding)|interpro:IPR000225(Armadillo)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR040122|rcsb pdb:2BKU|go:"GO:0006612"(protein targeting to membrane)|refseq:NP_013451.1|sgd:S000004339|dip:DIP-2357N|mint:Q06142 psi-mi:"MI:0465"(dip) crc64:8D3A0CB76F2E7C00 crc64:ED530F5313E75B06 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/06 2017/08/10 rogid:NyzC93xnBCb8DX/AH346lwg4u2A559292 rogid:ebWeXaUKiBFWgjdv9s2pz1GIqgI559292 rigid:4FGS69xwwNJvFc6wNxkSjq1hb9M false binding-associated region:1-65 - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P61970 uniprotkb:P14907 intact:EBI-591778|uniprotkb:P13662|uniprotkb:Q6IB67|uniprotkb:B2R4G7|ensembl:ENSP00000219169|ensembl:ENSP00000457022|ensembl:ENSP00000457989 intact:EBI-12265|uniprotkb:D6VWE3 psi-mi:ntf2_human(display_long)|uniprotkb:Placental protein 15(gene name synonym)|uniprotkb:NUTF2(gene name)|psi-mi:NUTF2(display_short)|uniprotkb:NTF2(gene name synonym) psi-mi:nsp1_yeast(display_long)|uniprotkb:NSP1(gene name)|psi-mi:NSP1(display_short)|uniprotkb:YJL041W(locus name)|uniprotkb:J1207(orf name)|uniprotkb:Nuclear pore protein NSP1(gene name synonym)|uniprotkb:Nucleoskeletal-like protein(gene name synonym)|uniprotkb:p110(gene name synonym) psi-mi:"MI:0047"(far western blotting) Jovanovic-Talisman et al. (2009) pubmed:19098896|doi:10.1038/nature07600|imex:IM-17852 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15747989|imex:IM-17852-10|dip:DIP-189298E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005787.1|refseq:NP_001308967.1|refseq:NP_001308968.1|refseq:NP_001308969.1|refseq:NP_001308970.1|dip:DIP-6057N|ensembl:ENSG00000102898(gene)|ensembl:ENST00000219169(transcript)|ensembl:ENST00000568396(transcript)|ensembl:ENST00000569436(transcript)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0044613"(nuclear pore central transport channel)|go:"GO:0051028"(mRNA transport)|go:"GO:0061608"(nuclear import signal receptor activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090204"(protein localization to nuclear pore)|go:"GO:1904046"(negative regulation of vascular endothelial growth factor production)|interpro:IPR002075(Nuclear transport factor 2)|interpro:IPR018222|interpro:IPR032710|rcsb pdb:1GY5 go:"GO:0000055"(ribosomal large subunit export from nucleus)|go:"GO:0000056"(ribosomal small subunit export from nucleus)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005643"(nuclear pore)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006409"(tRNA export from nucleus)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0007049"(cell cycle)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034399"(nuclear periphery)|go:"GO:0044613"(nuclear pore central transport channel)|go:"GO:0044615"(nuclear pore nuclear basket)|go:"GO:0097064"(ncRNA export from nucleus)|interpro:IPR007758(Nucleoporin, Nsp1-like, C-terminal)|interpro:IPR026010|rcsb pdb:1O6O|refseq:NP_012494.3|sgd:S000003577|mint:P14907|dip:DIP-1484N psi-mi:"MI:0465"(dip) - crc64:A258003CB1917810 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/06 2017/08/10 rogid:hDy30rHCK1a4LjUfAWtf1DEu8n89606 rogid:wFdC6D8JzkhJpF+k3qtnFj9+4pA559292 rigid:pGlXT+mGqfq9PKNZNX7pqjsoDoA false yellow fluorescent protein tag:c-c binding-associated region:30-591 - - psi-mi:"MI:0867"(tag visualisation by fluorescence) psi-mi:"MI:0867"(tag visualisation by fluorescence)