#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q9UXG1 uniprotkb:Q9UXG1 intact:EBI-8081298|intact:MINT-1896063|ensemblbacteria:AAK41071 intact:EBI-8081298|intact:MINT-1896063|ensemblbacteria:AAK41071 psi-mi:mcm_sacs2(display_long)|uniprotkb:MCM(gene name)|psi-mi:MCM(display_short)|uniprotkb:SSO0774(locus name) psi-mi:mcm_sacs2(display_long)|uniprotkb:MCM(gene name)|psi-mi:MCM(display_short)|uniprotkb:SSO0774(locus name) psi-mi:"MI:0071"(molecular sieving) Brewster et al. (2008) pubmed:19073923|doi:10.1073/pnas.0808037105|imex:IM-14380 taxid:273057(sulso)|taxid:273057("Sulfolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2)") taxid:273057(sulso)|taxid:273057("Sulfolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15745917|imex:IM-14380-1|dip:DIP-103432E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_009991364.1|dip:DIP-42884N|ensemblbacteria:AAK41071(transcript)|ensemblbacteria:SSO0774(gene)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0006260"(DNA replication)|go:"GO:0042555"(MCM complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001208(MCM)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR027417|interpro:IPR027925|interpro:IPR031327|interpro:IPR033762|interpro:IPR036388|interpro:IPR041562|rcsb pdb:2M45|rcsb pdb:2VL6|rcsb pdb:3F9V|rcsb pdb:4FDG|rcsb pdb:4R7Y|rcsb pdb:6WNZ refseq:WP_009991364.1|dip:DIP-42884N|ensemblbacteria:AAK41071(transcript)|ensemblbacteria:SSO0774(gene)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0006260"(DNA replication)|go:"GO:0042555"(MCM complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001208(MCM)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR027417|interpro:IPR027925|interpro:IPR031327|interpro:IPR033762|interpro:IPR036388|interpro:IPR041562|rcsb pdb:2M45|rcsb pdb:2VL6|rcsb pdb:3F9V|rcsb pdb:4FDG|rcsb pdb:4R7Y|rcsb pdb:6WNZ psi-mi:"MI:0465"(dip) comment:mint|function:"Has ATPase and DNA helicase activities. The latter preferentially melts 5'-tailed oligonucleotides and is stimulated by the SSB protein (single-stranded DNA binding protein)" comment:mint|function:"Has ATPase and DNA helicase activities. The latter preferentially melts 5'-tailed oligonucleotides and is stimulated by the SSB protein (single-stranded DNA binding protein)" full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/06 2017/08/10 rogid:n19Bp/+DLZYkodArLBB3ITcElgw273057 rogid:n19Bp/+DLZYkodArLBB3ITcElgw273057 rigid:UgwemN3pSjmsz2tPfwM0EOznzlk false necessary binding region:550-554|mutation disrupting interaction:557-557,556-556,555-555|mutation decreasing interaction:420-420,416-416|mutation decreasing interaction:191-191,189-189 necessary binding region:550-554|mutation disrupting interaction:557-557,556-556,555-555|mutation decreasing interaction:420-420,416-416|mutation decreasing interaction:191-191,189-189 - 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)