#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:O14936-4	uniprotkb:Q8IZU9	intact:EBI-12007726|ensembl:ENSP00000495291	intact:EBI-16427312|ensembl:ENSP00000435466|uniprotkb:Q3MIJ7|uniprotkb:Q6UWJ9|uniprotkb:Q6UWL5|uniprotkb:Q96JG0	psi-mi:o14936-4(display_long)|uniprotkb:CASK(gene name)|psi-mi:CASK(display_short)|uniprotkb:Calcium/calmodulin-dependent serine protein kinase(gene name synonym)|uniprotkb:LIN2(gene name synonym)|uniprotkb:Protein lin-2 homolog(gene name synonym)	psi-mi:kirr3_human(display_long)|uniprotkb:Kin of irregular chiasm-like protein 3(gene name synonym)|uniprotkb:Nephrin-like protein 2(gene name synonym)|uniprotkb:UNQ5923/PRO4502/PRO19814(orf name)|uniprotkb:KIRREL3(gene name)|psi-mi:KIRREL3(display_short)|uniprotkb:KIAA1867(gene name synonym)|uniprotkb:NEPH2(gene name synonym)	psi-mi:"MI:0663"(confocal microscopy)	Bhalla et al. (2008)	imex:IM-26169|pubmed:19012874	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16427626|imex:IM-26169-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-1215506(isoform-parent)|uniprotkb:O14936-4(isoform-parent)|ensembl:ENSG00000147044(gene)|ensembl:ENST00000646120(transcript)	ensembl:ENSG00000149571(gene)|ensembl:ENST00000525144(transcript)|go:"GO:0001764"(neuron migration)|go:"GO:0002121"(inter-male aggressive behavior)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0016021"(integral component of membrane)|go:"GO:0021740"(principal sensory nucleus of trigeminal nerve development)|go:"GO:0021766"(hippocampus development)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0043198"(dendritic shaft)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0072102"(glomerulus morphogenesis)|go:"GO:0098609"(cell-cell adhesion)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|rcsb pdb:2CRY|reactome:R-HSA-373753|refseq:NP_001155179.1|refseq:NP_115920.1|refseq:XP_011541333.1|refseq:XP_016873909.1	go:"GO:0005886"(plasma membrane)|go:"GO:0005737"(cytoplasm)	isoform-comment:Contains a phosphoserine at position 577.	-	figure legend:Fig 4B|comment:colocalization was shown  in regions of cell membrane and possibly cytoplasma.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-pc12)|taxid:10116(Rattus norvegicus PC12 cells)	-	2017/10/17	2017/10/17	rogid:wPk2DtY0JCvGelwtsIEz1Vdvo0w9606	rogid:y8nGWQDtny6F7KQi1/OYiJSzaEY9606	rigid:5EAFz3ERJd3MuHs/XhhNJiLT+/E	false	green fluorescent protein tag:n-n	v5 tag:c-c|his tag:c-c	-	-	psi-mi:"MI:1200"(immunocytochemistry)	psi-mi:"MI:1200"(immunocytochemistry)
uniprotkb:O14936-4	uniprotkb:Q8IZU9	intact:EBI-12007726|ensembl:ENSP00000495291	intact:EBI-16427312|ensembl:ENSP00000435466|uniprotkb:Q3MIJ7|uniprotkb:Q6UWJ9|uniprotkb:Q6UWL5|uniprotkb:Q96JG0	psi-mi:o14936-4(display_long)|uniprotkb:CASK(gene name)|psi-mi:CASK(display_short)|uniprotkb:Calcium/calmodulin-dependent serine protein kinase(gene name synonym)|uniprotkb:LIN2(gene name synonym)|uniprotkb:Protein lin-2 homolog(gene name synonym)	psi-mi:kirr3_human(display_long)|uniprotkb:Kin of irregular chiasm-like protein 3(gene name synonym)|uniprotkb:Nephrin-like protein 2(gene name synonym)|uniprotkb:UNQ5923/PRO4502/PRO19814(orf name)|uniprotkb:KIRREL3(gene name)|psi-mi:KIRREL3(display_short)|uniprotkb:KIAA1867(gene name synonym)|uniprotkb:NEPH2(gene name synonym)	psi-mi:"MI:0663"(confocal microscopy)	Bhalla et al. (2008)	imex:IM-26169|pubmed:19012874	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16427646|imex:IM-26169-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-1215506(isoform-parent)|uniprotkb:O14936-4(isoform-parent)|ensembl:ENSG00000147044(gene)|ensembl:ENST00000646120(transcript)	ensembl:ENSG00000149571(gene)|ensembl:ENST00000525144(transcript)|go:"GO:0001764"(neuron migration)|go:"GO:0002121"(inter-male aggressive behavior)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0016021"(integral component of membrane)|go:"GO:0021740"(principal sensory nucleus of trigeminal nerve development)|go:"GO:0021766"(hippocampus development)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0043198"(dendritic shaft)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0072102"(glomerulus morphogenesis)|go:"GO:0098609"(cell-cell adhesion)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|rcsb pdb:2CRY|reactome:R-HSA-373753|refseq:NP_001155179.1|refseq:NP_115920.1|refseq:XP_011541333.1|refseq:XP_016873909.1	go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)	isoform-comment:Contains a phosphoserine at position 577.	-	figure legend:Fig 4C|comment:colocalization was shown  in regions of cell membrane and possibly cytoplasma.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-ht22)|taxid:10090(mouse HT22 immortalized  hippocampal cell line)	-	2017/10/17	2017/10/17	rogid:wPk2DtY0JCvGelwtsIEz1Vdvo0w9606	rogid:y8nGWQDtny6F7KQi1/OYiJSzaEY9606	rigid:5EAFz3ERJd3MuHs/XhhNJiLT+/E	false	green fluorescent protein tag:n-n	v5 tag:c-c|his tag:c-c	-	-	psi-mi:"MI:1200"(immunocytochemistry)	psi-mi:"MI:1200"(immunocytochemistry)
uniprotkb:Q8IZU9	uniprotkb:O14936	intact:EBI-16427312|ensembl:ENSP00000435466|uniprotkb:Q3MIJ7|uniprotkb:Q6UWJ9|uniprotkb:Q6UWL5|uniprotkb:Q96JG0	intact:EBI-1215506|uniprotkb:Q5VT18|uniprotkb:Q5VT19|uniprotkb:Q66T42|uniprotkb:A6NES1|uniprotkb:O43215|uniprotkb:Q17RI4|uniprotkb:Q59HA0|uniprotkb:Q5VT16|uniprotkb:Q5VT17|uniprotkb:Q9BYH6|uniprotkb:Q9NYB2|uniprotkb:Q9NYB3|uniprotkb:B7ZKY0|ensembl:ENSP00000367405	psi-mi:kirr3_human(display_long)|uniprotkb:Kin of irregular chiasm-like protein 3(gene name synonym)|uniprotkb:Nephrin-like protein 2(gene name synonym)|uniprotkb:UNQ5923/PRO4502/PRO19814(orf name)|uniprotkb:KIRREL3(gene name)|psi-mi:KIRREL3(display_short)|uniprotkb:KIAA1867(gene name synonym)|uniprotkb:NEPH2(gene name synonym)	psi-mi:cskp_human(display_long)|uniprotkb:CASK(gene name)|psi-mi:CASK(display_short)|uniprotkb:LIN2(gene name synonym)|uniprotkb:Calcium/calmodulin-dependent serine protein kinase(gene name synonym)|uniprotkb:Protein lin-2 homolog(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Bhalla et al. (2008)	imex:IM-26169|pubmed:19012874	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16427788|imex:IM-26169-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000149571(gene)|ensembl:ENST00000525144(transcript)|go:"GO:0001764"(neuron migration)|go:"GO:0002121"(inter-male aggressive behavior)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0016021"(integral component of membrane)|go:"GO:0021740"(principal sensory nucleus of trigeminal nerve development)|go:"GO:0021766"(hippocampus development)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0043198"(dendritic shaft)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0072102"(glomerulus morphogenesis)|go:"GO:0098609"(cell-cell adhesion)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|rcsb pdb:2CRY|reactome:R-HSA-373753|refseq:NP_001155179.1|refseq:NP_115920.1|refseq:XP_011541333.1|refseq:XP_016873909.1	refseq:NP_001119526.1|refseq:NP_001119527.1|refseq:NP_003679.2|dip:DIP-38727N|ensembl:ENSG00000147044(gene)|ensembl:ENST00000378163(transcript)|go:"GO:0001953"(negative regulation of cell-matrix adhesion)|go:"GO:0004385"(guanylate kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005604"(basement membrane)|go:"GO:0005652"(nuclear lamina)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0007155"(cell adhesion)|go:"GO:0010839"(negative regulation of keratinocyte proliferation)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016363"(nuclear matrix)|go:"GO:0031982"(vesicle)|go:"GO:0042043"(neurexin family protein binding)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060170"(ciliary membrane)|go:"GO:0061045"(negative regulation of wound healing)|go:"GO:0070509"(calcium ion import)|go:"GO:0090280"(positive regulation of calcium ion import)|go:"GO:0090288"(negative regulation of cellular response to growth factor stimulus)|rcsb pdb:3MFT|rcsb pdb:3MFU|rcsb pdb:3TAC|rcsb pdb:6KMH|rcsb pdb:7OAI|rcsb pdb:7OAJ|rcsb pdb:7OAK|rcsb pdb:7OAL|reactome:R-HSA-212676|reactome:R-HSA-3000170|reactome:R-HSA-373753|reactome:R-HSA-6794361|reactome:R-HSA-9609736|reactome:R-HSA-9662360|reactome:R-HSA-9662361|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001452(Src homology-3)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR004172(L27)|interpro:IPR008144(Guanylate kinase)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR011009(Protein kinase-like)|interpro:IPR014775(L27, C-terminal)|interpro:IPR020590|interpro:IPR027417|interpro:IPR035473|interpro:IPR036028|interpro:IPR036034|interpro:IPR036892|mint:O14936|rcsb pdb:1KGD|rcsb pdb:1KWA|rcsb pdb:1ZL8|rcsb pdb:3C0G|rcsb pdb:3C0H|rcsb pdb:3C0I|rcsb pdb:3MFR|rcsb pdb:3MFS	-	-	-	figure legend:Fig 4 D/E|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/10/17	2017/10/18	rogid:y8nGWQDtny6F7KQi1/OYiJSzaEY9606	rogid:zTaBgQexJON3EVgJq9FHjf+aSCY9606	rigid:lduu7DE0igFP7pQRU+ryLkef5Fw	false	v5 tag:c-c|his tag:c-c	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q8IZU9	uniprotkb:O14936-4	intact:EBI-16427312|ensembl:ENSP00000435466|uniprotkb:Q3MIJ7|uniprotkb:Q6UWJ9|uniprotkb:Q6UWL5|uniprotkb:Q96JG0	intact:EBI-12007726|ensembl:ENSP00000495291	psi-mi:kirr3_human(display_long)|uniprotkb:Kin of irregular chiasm-like protein 3(gene name synonym)|uniprotkb:Nephrin-like protein 2(gene name synonym)|uniprotkb:UNQ5923/PRO4502/PRO19814(orf name)|uniprotkb:KIRREL3(gene name)|psi-mi:KIRREL3(display_short)|uniprotkb:KIAA1867(gene name synonym)|uniprotkb:NEPH2(gene name synonym)	psi-mi:o14936-4(display_long)|uniprotkb:CASK(gene name)|psi-mi:CASK(display_short)|uniprotkb:Calcium/calmodulin-dependent serine protein kinase(gene name synonym)|uniprotkb:LIN2(gene name synonym)|uniprotkb:Protein lin-2 homolog(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Bhalla et al. (2008)	imex:IM-26169|pubmed:19012874	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16427788|imex:IM-26169-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000149571(gene)|ensembl:ENST00000525144(transcript)|go:"GO:0001764"(neuron migration)|go:"GO:0002121"(inter-male aggressive behavior)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0016021"(integral component of membrane)|go:"GO:0021740"(principal sensory nucleus of trigeminal nerve development)|go:"GO:0021766"(hippocampus development)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0043198"(dendritic shaft)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0072102"(glomerulus morphogenesis)|go:"GO:0098609"(cell-cell adhesion)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|rcsb pdb:2CRY|reactome:R-HSA-373753|refseq:NP_001155179.1|refseq:NP_115920.1|refseq:XP_011541333.1|refseq:XP_016873909.1	intact:EBI-1215506(isoform-parent)|uniprotkb:O14936-4(isoform-parent)|ensembl:ENSG00000147044(gene)|ensembl:ENST00000646120(transcript)	-	-	isoform-comment:Contains a phosphoserine at position 577.	figure legend:Fig 4 D/E|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/10/17	2017/10/18	rogid:y8nGWQDtny6F7KQi1/OYiJSzaEY9606	rogid:wPk2DtY0JCvGelwtsIEz1Vdvo0w9606	rigid:lduu7DE0igFP7pQRU+ryLkef5Fw	false	v5 tag:c-c|his tag:c-c	green fluorescent protein tag:n-n	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0705"(anti tag western blot)