#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q57818 uniprotkb:Q57839 intact:EBI-15739382|ensemblbacteria:AAB98361 intact:EBI-15739363|ensemblbacteria:AAB98386 psi-mi:spt5_metja(display_long)|uniprotkb:spt5(gene name)|psi-mi:spt5(display_short)|uniprotkb:MJ0372(locus name) psi-mi:spt4_metja(display_long)|uniprotkb:spt4(gene name)|psi-mi:spt4(display_short)|uniprotkb:rpoE''(gene name synonym)|uniprotkb:rpoE2(gene name synonym)|uniprotkb:MJ0396(locus name) psi-mi:"MI:0096"(pull down) Guo et al. (2008) pubmed:19000817|doi:10.1016/j.str.2008.08.013|imex:IM-9604 taxid:243232(metja)|taxid:243232("Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440)") taxid:243232(metja)|taxid:243232("Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15739406|imex:IM-9604-2|dip:DIP-88295E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAB98361(transcript)|ensemblbacteria:MJ_0372(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0005840"(ribosome)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0032784"(regulation of DNA-templated transcription, elongation)|interpro:IPR005100(Supt5 repeat)|interpro:IPR005824(KOW)|interpro:IPR005825(Ribosomal protein L24/L26, conserved site)|interpro:IPR006645(Transcription antitermination protein, NusG, N-terminal)|interpro:IPR008991(Translation protein SH3-like)|interpro:IPR011590(Ribosomal protein L26e, archaeal)|interpro:IPR014722(Translation protein SH3-like, subgroup)|interpro:IPR036735|interpro:IPR039659|rcsb pdb:3EWG|rcsb pdb:3LPE|rcsb pdb:4ZN1|rcsb pdb:4ZN3|dip:DIP-46333N|refseq:WP_010869871.1 ensemblbacteria:AAB98386(transcript)|ensemblbacteria:MJ_0396(gene)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008270"(zinc ion binding)|interpro:IPR007178(DNA-directed RNA polymerase, RpoE2, archaeal)|interpro:IPR022800|interpro:IPR029040|interpro:IPR038589|rcsb pdb:3LPE|rcsb pdb:4ZN1|rcsb pdb:4ZN3|dip:DIP-46332N|refseq:WP_010869895.1 psi-mi:"MI:0465"(dip) crc64:A8D917571BF5F215 crc64:CFC635FF7C1B0919 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/06 2017/08/10 rogid:HLPIKsHnp3Nm22S7/mb8xwLFRfE243232 rogid:woRcXhXDwJ2qXKOM/lKl4a6WTOc243232 rigid:3BJ3QiTDfXueI7Y08z9VJQGxb/A false - glutathione s tranferase tag:n-n - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:P27692 uniprotkb:P32914 intact:EBI-17937|uniprotkb:D6VZG4|ensemblfungi:YML010W intact:EBI-17928|uniprotkb:D6VUJ8|uniprotkb:Q0P6T7|uniprotkb:Q45U23|ensemblfungi:YGR063C psi-mi:spt5_yeast(display_long)|uniprotkb:SPT5(gene name)|psi-mi:SPT5(display_short)|uniprotkb:YML010W(locus name)|uniprotkb:YM9571.08(orf name)|uniprotkb:Chromatin elongation factor SPT5(gene name synonym) psi-mi:spt4_yeast(display_long)|uniprotkb:YGR063C(locus name)|uniprotkb:SPT4(gene name)|psi-mi:SPT4(display_short)|uniprotkb:Chromatin elongation factor SPT4(gene name synonym) psi-mi:"MI:0029"(cosedimentation through density gradient) Guo et al. (2008) pubmed:19000817|doi:10.1016/j.str.2008.08.013|imex:IM-9604 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15739447|imex:IM-9604-4|dip:DIP-88296E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013703.1|sgd:S000004470|ensemblfungi:YML010W(gene)|ensemblfungi:YML010W_mRNA(transcript)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0001042"(RNA polymerase I core binding)|go:"GO:0001179"(RNA polymerase I general transcription initiation factor binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0008298"(intracellular mRNA localization)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0017070"(U6 snRNA binding)|go:"GO:0019843"(rRNA binding)|go:"GO:0030619"(U1 snRNA binding)|go:"GO:0030620"(U2 snRNA binding)|go:"GO:0030621"(U4 snRNA binding)|go:"GO:0030623"(U5 snRNA binding)|go:"GO:0032044"(DSIF complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0070990"(snRNP binding)|go:"GO:2000232"(regulation of rRNA processing)|go:"GO:2001208"(negative regulation of transcription elongation by RNA polymerase I)|go:"GO:2001209"(positive regulation of transcription elongation from RNA polymerase I promoter)|interpro:IPR005100(Supt5 repeat)|interpro:IPR005824(KOW)|interpro:IPR006645(Transcription antitermination protein, NusG, N-terminal)|interpro:IPR008991(Translation protein SH3-like)|interpro:IPR014722(Translation protein SH3-like, subgroup)|interpro:IPR017071(Transcription elongation factor Spt5)|interpro:IPR022581|interpro:IPR024945|interpro:IPR036735|interpro:IPR039385|interpro:IPR039659|interpro:IPR041973|interpro:IPR041975|interpro:IPR041976|interpro:IPR041977|interpro:IPR041978|rcsb pdb:2EXU|rcsb pdb:4YTK|rcsb pdb:4YTL|reactome:R-SCE-113418|reactome:R-SCE-674695|reactome:R-SCE-6796648|reactome:R-SCE-72086|reactome:R-SCE-75955|reactome:R-SCE-77075|go:"GO:0090262"(regulation of transcription-coupled nucleotide-excision repair)|dip:DIP-6621N|mint:P27692 sgd:S000003295|ensemblfungi:YGR063C(gene)|ensemblfungi:YGR063C_mRNA(transcript)|go:"GO:0000182"(rDNA binding)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000776"(kinetochore)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0001181"(RNA polymerase I general transcription initiation factor activity)|go:"GO:0006325"(chromatin organization)|go:"GO:0006342"|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0006397"(mRNA processing)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008298"(intracellular mRNA localization)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0032044"(DSIF complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0034243"(regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0090262"(regulation of transcription-coupled nucleotide-excision repair)|go:"GO:2000232"(regulation of rRNA processing)|go:"GO:2001208"(negative regulation of transcription elongation by RNA polymerase I)|go:"GO:2001209"(positive regulation of transcription elongation from RNA polymerase I promoter)|interpro:IPR009287(Transcription initiation Spt4)|interpro:IPR022800|interpro:IPR029040|interpro:IPR038510|rcsb pdb:2EXU|reactome:R-SCE-113418|reactome:R-SCE-674695|reactome:R-SCE-6796648|reactome:R-SCE-75955|refseq:NP_011577.3|dip:DIP-2078N|mint:P32914 psi-mi:"MI:0465"(dip) crc64:E4324DB6B1E4721A crc64:59C164193ABA883B full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/06 2017/08/10 rogid:5atgyJBgDNSv1Jlg+SpCuA45MjU559292 rogid:MC4Di+maCZ0kgCpzXXV0KP82pwU559292 rigid:1qKg72P33LZSk4536GsJDNBpUF4 false - flag tag:n-n - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q57818 uniprotkb:Q57839 intact:EBI-15739382|ensemblbacteria:AAB98361 intact:EBI-15739363|ensemblbacteria:AAB98386 psi-mi:spt5_metja(display_long)|uniprotkb:spt5(gene name)|psi-mi:spt5(display_short)|uniprotkb:MJ0372(locus name) psi-mi:spt4_metja(display_long)|uniprotkb:spt4(gene name)|psi-mi:spt4(display_short)|uniprotkb:rpoE''(gene name synonym)|uniprotkb:rpoE2(gene name synonym)|uniprotkb:MJ0396(locus name) psi-mi:"MI:0096"(pull down) Guo et al. (2008) pubmed:19000817|doi:10.1016/j.str.2008.08.013|imex:IM-9604 taxid:243232(metja)|taxid:243232("Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440)") taxid:243232(metja)|taxid:243232("Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15739466|imex:IM-9604-5|dip:DIP-88295E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAB98361(transcript)|ensemblbacteria:MJ_0372(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0005840"(ribosome)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0032784"(regulation of DNA-templated transcription, elongation)|interpro:IPR005100(Supt5 repeat)|interpro:IPR005824(KOW)|interpro:IPR005825(Ribosomal protein L24/L26, conserved site)|interpro:IPR006645(Transcription antitermination protein, NusG, N-terminal)|interpro:IPR008991(Translation protein SH3-like)|interpro:IPR011590(Ribosomal protein L26e, archaeal)|interpro:IPR014722(Translation protein SH3-like, subgroup)|interpro:IPR036735|interpro:IPR039659|rcsb pdb:3EWG|rcsb pdb:3LPE|rcsb pdb:4ZN1|rcsb pdb:4ZN3|dip:DIP-46333N|refseq:WP_010869871.1 ensemblbacteria:AAB98386(transcript)|ensemblbacteria:MJ_0396(gene)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008270"(zinc ion binding)|interpro:IPR007178(DNA-directed RNA polymerase, RpoE2, archaeal)|interpro:IPR022800|interpro:IPR029040|interpro:IPR038589|rcsb pdb:3LPE|rcsb pdb:4ZN1|rcsb pdb:4ZN3|dip:DIP-46332N|refseq:WP_010869895.1 psi-mi:"MI:0465"(dip) crc64:A8D917571BF5F215 crc64:CFC635FF7C1B0919 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/06 2017/08/10 rogid:HLPIKsHnp3Nm22S7/mb8xwLFRfE243232 rogid:woRcXhXDwJ2qXKOM/lKl4a6WTOc243232 rigid:3BJ3QiTDfXueI7Y08z9VJQGxb/A false his tag:n-n - - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:P27692 uniprotkb:P32914 intact:EBI-17937|uniprotkb:D6VZG4|ensemblfungi:YML010W intact:EBI-17928|uniprotkb:D6VUJ8|uniprotkb:Q0P6T7|uniprotkb:Q45U23|ensemblfungi:YGR063C psi-mi:spt5_yeast(display_long)|uniprotkb:SPT5(gene name)|psi-mi:SPT5(display_short)|uniprotkb:YML010W(locus name)|uniprotkb:YM9571.08(orf name)|uniprotkb:Chromatin elongation factor SPT5(gene name synonym) psi-mi:spt4_yeast(display_long)|uniprotkb:YGR063C(locus name)|uniprotkb:SPT4(gene name)|psi-mi:SPT4(display_short)|uniprotkb:Chromatin elongation factor SPT4(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Guo et al. (2008) pubmed:19000817|doi:10.1016/j.str.2008.08.013|imex:IM-9604 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15739485|imex:IM-9604-6|dip:DIP-88296E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013703.1|sgd:S000004470|ensemblfungi:YML010W(gene)|ensemblfungi:YML010W_mRNA(transcript)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0001042"(RNA polymerase I core binding)|go:"GO:0001179"(RNA polymerase I general transcription initiation factor binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0008298"(intracellular mRNA localization)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0017070"(U6 snRNA binding)|go:"GO:0019843"(rRNA binding)|go:"GO:0030619"(U1 snRNA binding)|go:"GO:0030620"(U2 snRNA binding)|go:"GO:0030621"(U4 snRNA binding)|go:"GO:0030623"(U5 snRNA binding)|go:"GO:0032044"(DSIF complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0070990"(snRNP binding)|go:"GO:2000232"(regulation of rRNA processing)|go:"GO:2001208"(negative regulation of transcription elongation by RNA polymerase I)|go:"GO:2001209"(positive regulation of transcription elongation from RNA polymerase I promoter)|interpro:IPR005100(Supt5 repeat)|interpro:IPR005824(KOW)|interpro:IPR006645(Transcription antitermination protein, NusG, N-terminal)|interpro:IPR008991(Translation protein SH3-like)|interpro:IPR014722(Translation protein SH3-like, subgroup)|interpro:IPR017071(Transcription elongation factor Spt5)|interpro:IPR022581|interpro:IPR024945|interpro:IPR036735|interpro:IPR039385|interpro:IPR039659|interpro:IPR041973|interpro:IPR041975|interpro:IPR041976|interpro:IPR041977|interpro:IPR041978|rcsb pdb:2EXU|rcsb pdb:4YTK|rcsb pdb:4YTL|reactome:R-SCE-113418|reactome:R-SCE-674695|reactome:R-SCE-6796648|reactome:R-SCE-72086|reactome:R-SCE-75955|reactome:R-SCE-77075|go:"GO:0090262"(regulation of transcription-coupled nucleotide-excision repair)|dip:DIP-6621N|mint:P27692 sgd:S000003295|ensemblfungi:YGR063C(gene)|ensemblfungi:YGR063C_mRNA(transcript)|go:"GO:0000182"(rDNA binding)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000776"(kinetochore)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0001181"(RNA polymerase I general transcription initiation factor activity)|go:"GO:0006325"(chromatin organization)|go:"GO:0006342"|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0006397"(mRNA processing)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008298"(intracellular mRNA localization)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0032044"(DSIF complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0034243"(regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0090262"(regulation of transcription-coupled nucleotide-excision repair)|go:"GO:2000232"(regulation of rRNA processing)|go:"GO:2001208"(negative regulation of transcription elongation by RNA polymerase I)|go:"GO:2001209"(positive regulation of transcription elongation from RNA polymerase I promoter)|interpro:IPR009287(Transcription initiation Spt4)|interpro:IPR022800|interpro:IPR029040|interpro:IPR038510|rcsb pdb:2EXU|reactome:R-SCE-113418|reactome:R-SCE-674695|reactome:R-SCE-6796648|reactome:R-SCE-75955|refseq:NP_011577.3|dip:DIP-2078N|mint:P32914 psi-mi:"MI:0465"(dip) crc64:E4324DB6B1E4721A crc64:59C164193ABA883B full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/06 2017/08/10 rogid:5atgyJBgDNSv1Jlg+SpCuA45MjU559292 rogid:MC4Di+maCZ0kgCpzXXV0KP82pwU559292 rigid:1qKg72P33LZSk4536GsJDNBpUF4 false - flag tag:n-n - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P27692 uniprotkb:P32914 intact:EBI-17937|uniprotkb:D6VZG4|ensemblfungi:YML010W intact:EBI-17928|uniprotkb:D6VUJ8|uniprotkb:Q0P6T7|uniprotkb:Q45U23|ensemblfungi:YGR063C psi-mi:spt5_yeast(display_long)|uniprotkb:SPT5(gene name)|psi-mi:SPT5(display_short)|uniprotkb:YML010W(locus name)|uniprotkb:YM9571.08(orf name)|uniprotkb:Chromatin elongation factor SPT5(gene name synonym) psi-mi:spt4_yeast(display_long)|uniprotkb:YGR063C(locus name)|uniprotkb:SPT4(gene name)|psi-mi:SPT4(display_short)|uniprotkb:Chromatin elongation factor SPT4(gene name synonym) psi-mi:"MI:0114"(x-ray crystallography) Guo et al. (2008) pubmed:19000817|doi:10.1016/j.str.2008.08.013|imex:IM-9604 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15739426|imex:IM-9604-3|dip:DIP-88296E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013703.1|sgd:S000004470|ensemblfungi:YML010W(gene)|ensemblfungi:YML010W_mRNA(transcript)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0001042"(RNA polymerase I core binding)|go:"GO:0001179"(RNA polymerase I general transcription initiation factor binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0008298"(intracellular mRNA localization)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0017070"(U6 snRNA binding)|go:"GO:0019843"(rRNA binding)|go:"GO:0030619"(U1 snRNA binding)|go:"GO:0030620"(U2 snRNA binding)|go:"GO:0030621"(U4 snRNA binding)|go:"GO:0030623"(U5 snRNA binding)|go:"GO:0032044"(DSIF complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0070990"(snRNP binding)|go:"GO:2000232"(regulation of rRNA processing)|go:"GO:2001208"(negative regulation of transcription elongation by RNA polymerase I)|go:"GO:2001209"(positive regulation of transcription elongation from RNA polymerase I promoter)|interpro:IPR005100(Supt5 repeat)|interpro:IPR005824(KOW)|interpro:IPR006645(Transcription antitermination protein, NusG, N-terminal)|interpro:IPR008991(Translation protein SH3-like)|interpro:IPR014722(Translation protein SH3-like, subgroup)|interpro:IPR017071(Transcription elongation factor Spt5)|interpro:IPR022581|interpro:IPR024945|interpro:IPR036735|interpro:IPR039385|interpro:IPR039659|interpro:IPR041973|interpro:IPR041975|interpro:IPR041976|interpro:IPR041977|interpro:IPR041978|rcsb pdb:2EXU|rcsb pdb:4YTK|rcsb pdb:4YTL|reactome:R-SCE-113418|reactome:R-SCE-674695|reactome:R-SCE-6796648|reactome:R-SCE-72086|reactome:R-SCE-75955|reactome:R-SCE-77075|go:"GO:0090262"(regulation of transcription-coupled nucleotide-excision repair)|dip:DIP-6621N|mint:P27692 sgd:S000003295|ensemblfungi:YGR063C(gene)|ensemblfungi:YGR063C_mRNA(transcript)|go:"GO:0000182"(rDNA binding)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000776"(kinetochore)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0001181"(RNA polymerase I general transcription initiation factor activity)|go:"GO:0006325"(chromatin organization)|go:"GO:0006342"|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0006397"(mRNA processing)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008298"(intracellular mRNA localization)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0032044"(DSIF complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0034243"(regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0090262"(regulation of transcription-coupled nucleotide-excision repair)|go:"GO:2000232"(regulation of rRNA processing)|go:"GO:2001208"(negative regulation of transcription elongation by RNA polymerase I)|go:"GO:2001209"(positive regulation of transcription elongation from RNA polymerase I promoter)|interpro:IPR009287(Transcription initiation Spt4)|interpro:IPR022800|interpro:IPR029040|interpro:IPR038510|rcsb pdb:2EXU|reactome:R-SCE-113418|reactome:R-SCE-674695|reactome:R-SCE-6796648|reactome:R-SCE-75955|refseq:NP_011577.3|dip:DIP-2078N|mint:P32914 psi-mi:"MI:0465"(dip) crc64:E4324DB6B1E4721A crc64:59C164193ABA883B full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/06 2017/08/10 rogid:5atgyJBgDNSv1Jlg+SpCuA45MjU559292 rogid:MC4Di+maCZ0kgCpzXXV0KP82pwU559292 rigid:1qKg72P33LZSk4536GsJDNBpUF4 false binding-associated region:285-375 binding-associated region:1-99 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q57818 uniprotkb:Q57839 intact:EBI-15739382|ensemblbacteria:AAB98361 intact:EBI-15739363|ensemblbacteria:AAB98386 psi-mi:spt5_metja(display_long)|uniprotkb:spt5(gene name)|psi-mi:spt5(display_short)|uniprotkb:MJ0372(locus name) psi-mi:spt4_metja(display_long)|uniprotkb:spt4(gene name)|psi-mi:spt4(display_short)|uniprotkb:rpoE''(gene name synonym)|uniprotkb:rpoE2(gene name synonym)|uniprotkb:MJ0396(locus name) psi-mi:"MI:0071"(molecular sieving) Guo et al. (2008) pubmed:19000817|doi:10.1016/j.str.2008.08.013|imex:IM-9604 taxid:243232(metja)|taxid:243232("Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440)") taxid:243232(metja)|taxid:243232("Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15739504|imex:IM-9604-1|dip:DIP-88295E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:AAB98361(transcript)|ensemblbacteria:MJ_0372(gene)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0005840"(ribosome)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0032784"(regulation of DNA-templated transcription, elongation)|interpro:IPR005100(Supt5 repeat)|interpro:IPR005824(KOW)|interpro:IPR005825(Ribosomal protein L24/L26, conserved site)|interpro:IPR006645(Transcription antitermination protein, NusG, N-terminal)|interpro:IPR008991(Translation protein SH3-like)|interpro:IPR011590(Ribosomal protein L26e, archaeal)|interpro:IPR014722(Translation protein SH3-like, subgroup)|interpro:IPR036735|interpro:IPR039659|rcsb pdb:3EWG|rcsb pdb:3LPE|rcsb pdb:4ZN1|rcsb pdb:4ZN3|dip:DIP-46333N|refseq:WP_010869871.1 ensemblbacteria:AAB98386(transcript)|ensemblbacteria:MJ_0396(gene)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008270"(zinc ion binding)|interpro:IPR007178(DNA-directed RNA polymerase, RpoE2, archaeal)|interpro:IPR022800|interpro:IPR029040|interpro:IPR038589|rcsb pdb:3LPE|rcsb pdb:4ZN1|rcsb pdb:4ZN3|dip:DIP-46332N|refseq:WP_010869895.1 psi-mi:"MI:0465"(dip) crc64:A8D917571BF5F215 crc64:CFC635FF7C1B0919 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/06 2017/08/10 rogid:HLPIKsHnp3Nm22S7/mb8xwLFRfE243232 rogid:woRcXhXDwJ2qXKOM/lKl4a6WTOc243232 rigid:3BJ3QiTDfXueI7Y08z9VJQGxb/A false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)