#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P58660	uniprotkb:Q91YI4	intact:EBI-8344379|intact:MINT-4089832|ensembl:ENSMUSP00000131003	intact:EBI-994161|uniprotkb:Q3TCM2|uniprotkb:Q5F2D8|uniprotkb:Q5F2E0|ensembl:ENSMUSP00000099623|ensembl:ENSMUSP00000099624	psi-mi:car10_mouse(display_long)|uniprotkb:Card10(gene name)|psi-mi:Card10(display_short)|uniprotkb:Bimp1(gene name synonym)|uniprotkb:Bcl10-interacting MAGUK protein 1(gene name synonym)	psi-mi:arrb2_mouse(display_long)|uniprotkb:Arrestin beta-2(gene name synonym)|uniprotkb:Arrb2(gene name)|psi-mi:Arrb2(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Sun et al. (2008)	pubmed:18952848|doi:10.1073/pnas.0802701105|imex:IM-22471	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15736828|imex:IM-22471-1|dip:DIP-196227E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_570929.2|dip:DIP-60780N|ensembl:ENSMUSG00000033170(gene)|ensembl:ENSMUST00000170584(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007250"(activation of NF-kappaB-inducing kinase activity)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0050700"(CARD domain binding)|go:"GO:0090051"(negative regulation of cell migration involved in sprouting angiogenesis)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|interpro:IPR001315(Caspase Recruitment)|interpro:IPR011029(DEATH-like)|interpro:IPR027417|interpro:IPR042140|mint:P58660	refseq:NP_001258287.1|refseq:NP_001258288.1|refseq:NP_001258289.1|refseq:NP_663404.1|ensembl:ENSMUSG00000060216(gene)|ensembl:ENSMUST00000102563(transcript)|ensembl:ENSMUST00000102564(transcript)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045953"(negative regulation of natural killer cell mediated cytotoxicity)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050965"(detection of temperature stimulus involved in sensory perception of pain)|go:"GO:0051019"(mitogen-activated protein kinase binding)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0051928"(positive regulation of calcium ion transport)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071889"(14-3-3 protein binding)|go:"GO:0090201"(negative regulation of release of cytochrome c from mitochondria)|go:"GO:1904037"(positive regulation of epithelial cell apoptotic process)|go:"GO:1990763"(arrestin family protein binding)|go:"GO:2000573"(positive regulation of DNA biosynthetic process)|go:"GO:2000727"(positive regulation of cardiac muscle cell differentiation)|interpro:IPR000698(Arrestin)|interpro:IPR011021(Arrestin-like, N-terminal)|interpro:IPR011022(Arrestin-like, C-terminal)|interpro:IPR014752(Arrestin, C-terminal)|interpro:IPR014753(Arrestin, N-terminal)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR017864|reactome:R-MMU-418555|reactome:R-MMU-456926|reactome:R-MMU-5099900|reactome:R-MMU-5635838|reactome:R-MMU-5674135|reactome:R-MMU-5689880|reactome:R-MMU-8856825|reactome:R-MMU-8856828|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002031"(G protein-coupled receptor internalization)|go:"GO:0002032"(desensitization of G protein-coupled receptor signaling pathway by arrestin)|go:"GO:0002092"(positive regulation of receptor internalization)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006897"(endocytosis)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007420"(brain development)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0008277"(regulation of G protein-coupled receptor signaling pathway)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015031"(protein transport)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031623"(receptor internalization)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031691"(alpha-1A adrenergic receptor binding)|go:"GO:0031692"(alpha-1B adrenergic receptor binding)|go:"GO:0031701"(angiotensin receptor binding)|go:"GO:0031702"(type 1 angiotensin receptor binding)|go:"GO:0031748"(D1 dopamine receptor binding)|go:"GO:0031762"(follicle-stimulating hormone receptor binding)|go:"GO:0031826"(type 2A serotonin receptor binding)|go:"GO:0031859"(platelet activating factor receptor binding)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032226"(positive regulation of synaptic transmission, dopaminergic)|go:"GO:0032691"(negative regulation of interleukin-1 beta production)|go:"GO:0032695"(negative regulation of interleukin-12 production)|go:"GO:0032715"(negative regulation of interleukin-6 production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034122"(negative regulation of toll-like receptor signaling pathway)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0034392"(negative regulation of smooth muscle cell apoptotic process)|go:"GO:0042699"(follicle-stimulating hormone signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043197"(dendritic spine)|go:"GO:0043422"(protein kinase B binding)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0007628"(adult walking behavior)|dip:DIP-36064N	psi-mi:"MI:0465"(dip)	comment:mint|function:Activates NF-kappa-B via BCL10 and IKK	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse)|taxid:10090(Mus musculus)	-	2017/08/06	2017/08/10	rogid:TOvznGAAWR2wSI4PNokGO1pJY3010090	rogid:0jHDvt5w5ng+xsZj2vwjhSibWeE10090	rigid:fFzlux2zFBTQQgZPET5Y8l2KvF4	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P58660	uniprotkb:Q8BWG8	intact:EBI-8344379|intact:MINT-4089832|ensembl:ENSMUSP00000131003	intact:EBI-641778|uniprotkb:Q3UH95|uniprotkb:Q8BTJ5|ensembl:ENSMUSP00000095866	psi-mi:car10_mouse(display_long)|uniprotkb:Card10(gene name)|psi-mi:Card10(display_short)|uniprotkb:Bimp1(gene name synonym)|uniprotkb:Bcl10-interacting MAGUK protein 1(gene name synonym)	psi-mi:arrb1_mouse(display_long)|uniprotkb:Arrestin beta-1(gene name synonym)|uniprotkb:Arrb1(gene name)|psi-mi:Arrb1(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Sun et al. (2008)	pubmed:18952848|doi:10.1073/pnas.0802701105|imex:IM-22471	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15736828|imex:IM-22471-1|dip:DIP-196227E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_570929.2|dip:DIP-60780N|ensembl:ENSMUSG00000033170(gene)|ensembl:ENSMUST00000170584(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007250"(activation of NF-kappaB-inducing kinase activity)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0050700"(CARD domain binding)|go:"GO:0090051"(negative regulation of cell migration involved in sprouting angiogenesis)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|interpro:IPR001315(Caspase Recruitment)|interpro:IPR011029(DEATH-like)|interpro:IPR027417|interpro:IPR042140|mint:P58660	refseq:NP_796205.1|refseq:NP_835738.1|dip:DIP-49444N|ensembl:ENSMUSG00000018909(gene)|ensembl:ENSMUST00000098266(transcript)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0000785"(chromatin)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002031"(G protein-coupled receptor internalization)|go:"GO:0002092"(positive regulation of receptor internalization)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005159"(insulin-like growth factor receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007602"(phototransduction)|go:"GO:0008277"(regulation of G protein-coupled receptor signaling pathway)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015031"(protein transport)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0019899"(enzyme binding)|go:"GO:0030276"(clathrin binding)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0031143"(pseudopodium)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031434"(mitogen-activated protein kinase kinase binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031691"(alpha-1A adrenergic receptor binding)|go:"GO:0031692"(alpha-1B adrenergic receptor binding)|go:"GO:0031701"(angiotensin receptor binding)|go:"GO:0031762"(follicle-stimulating hormone receptor binding)|go:"GO:0031896"(V2 vasopressin receptor binding)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032715"(negative regulation of interleukin-6 production)|go:"GO:0032717"(negative regulation of interleukin-8 production)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0034393"(positive regulation of smooth muscle cell apoptotic process)|go:"GO:0035025"(positive regulation of Rho protein signal transduction)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0035612"(AP-2 adaptor complex binding)|go:"GO:0035615"(clathrin adaptor activity)|go:"GO:0035774"(positive regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0042699"(follicle-stimulating hormone signaling pathway)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043027"(cysteine-type endopeptidase inhibitor activity involved in apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043149"(stress fiber assembly)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043197"(dendritic spine)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045309"(protein phosphorylated amino acid binding)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0090240"(positive regulation of histone H4 acetylation)|go:"GO:1990763"(arrestin family protein binding)|interpro:IPR000698(Arrestin)|interpro:IPR011021(Arrestin-like, N-terminal)|interpro:IPR011022(Arrestin-like, C-terminal)|interpro:IPR014752(Arrestin, C-terminal)|interpro:IPR014753(Arrestin, N-terminal)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR017864|mint:Q8BWG8|reactome:R-MMU-432720|reactome:R-MMU-432722|reactome:R-MMU-456926|reactome:R-MMU-5635838|reactome:R-MMU-5674135|reactome:R-MMU-5689880|reactome:R-MMU-8856825|reactome:R-MMU-8856828|reactome:R-MMU-418555	psi-mi:"MI:0465"(dip)	comment:mint|function:Activates NF-kappa-B via BCL10 and IKK	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse)|taxid:10090(Mus musculus)	-	2017/08/06	2017/08/10	rogid:TOvznGAAWR2wSI4PNokGO1pJY3010090	rogid:QnjSypgRI1Aym+xBu3vpHxVSAD010090	rigid:fFzlux2zFBTQQgZPET5Y8l2KvF4	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P58660	uniprotkb:Q8BWG8	intact:EBI-8344379|intact:MINT-4089832|ensembl:ENSMUSP00000131003	intact:EBI-641778|uniprotkb:Q3UH95|uniprotkb:Q8BTJ5|ensembl:ENSMUSP00000095866	psi-mi:car10_mouse(display_long)|uniprotkb:Card10(gene name)|psi-mi:Card10(display_short)|uniprotkb:Bimp1(gene name synonym)|uniprotkb:Bcl10-interacting MAGUK protein 1(gene name synonym)	psi-mi:arrb1_mouse(display_long)|uniprotkb:Arrestin beta-1(gene name synonym)|uniprotkb:Arrb1(gene name)|psi-mi:Arrb1(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Sun et al. (2008)	pubmed:18952848|doi:10.1073/pnas.0802701105|imex:IM-22471	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15736870|imex:IM-22471-3|dip:DIP-196225E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_570929.2|dip:DIP-60780N|ensembl:ENSMUSG00000033170(gene)|ensembl:ENSMUST00000170584(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007250"(activation of NF-kappaB-inducing kinase activity)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0050700"(CARD domain binding)|go:"GO:0090051"(negative regulation of cell migration involved in sprouting angiogenesis)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|interpro:IPR001315(Caspase Recruitment)|interpro:IPR011029(DEATH-like)|interpro:IPR027417|interpro:IPR042140|mint:P58660	refseq:NP_796205.1|refseq:NP_835738.1|dip:DIP-49444N|ensembl:ENSMUSG00000018909(gene)|ensembl:ENSMUST00000098266(transcript)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0000785"(chromatin)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002031"(G protein-coupled receptor internalization)|go:"GO:0002092"(positive regulation of receptor internalization)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005159"(insulin-like growth factor receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007602"(phototransduction)|go:"GO:0008277"(regulation of G protein-coupled receptor signaling pathway)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015031"(protein transport)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0019899"(enzyme binding)|go:"GO:0030276"(clathrin binding)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0031143"(pseudopodium)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031434"(mitogen-activated protein kinase kinase binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031691"(alpha-1A adrenergic receptor binding)|go:"GO:0031692"(alpha-1B adrenergic receptor binding)|go:"GO:0031701"(angiotensin receptor binding)|go:"GO:0031762"(follicle-stimulating hormone receptor binding)|go:"GO:0031896"(V2 vasopressin receptor binding)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032715"(negative regulation of interleukin-6 production)|go:"GO:0032717"(negative regulation of interleukin-8 production)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0034393"(positive regulation of smooth muscle cell apoptotic process)|go:"GO:0035025"(positive regulation of Rho protein signal transduction)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0035612"(AP-2 adaptor complex binding)|go:"GO:0035615"(clathrin adaptor activity)|go:"GO:0035774"(positive regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0042699"(follicle-stimulating hormone signaling pathway)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043027"(cysteine-type endopeptidase inhibitor activity involved in apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043149"(stress fiber assembly)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043197"(dendritic spine)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045309"(protein phosphorylated amino acid binding)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0090240"(positive regulation of histone H4 acetylation)|go:"GO:1990763"(arrestin family protein binding)|interpro:IPR000698(Arrestin)|interpro:IPR011021(Arrestin-like, N-terminal)|interpro:IPR011022(Arrestin-like, C-terminal)|interpro:IPR014752(Arrestin, C-terminal)|interpro:IPR014753(Arrestin, N-terminal)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR017864|mint:Q8BWG8|reactome:R-MMU-432720|reactome:R-MMU-432722|reactome:R-MMU-456926|reactome:R-MMU-5635838|reactome:R-MMU-5674135|reactome:R-MMU-5689880|reactome:R-MMU-8856825|reactome:R-MMU-8856828|reactome:R-MMU-418555	psi-mi:"MI:0465"(dip)	comment:mint|function:Activates NF-kappa-B via BCL10 and IKK	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2017/08/06	2017/08/10	rogid:TOvznGAAWR2wSI4PNokGO1pJY3010090	rogid:QnjSypgRI1Aym+xBu3vpHxVSAD010090	rigid:x5CSyvOQ1N/RG5wdSeKT4+1QYVY	false	ha tag:c-c	flag tag:c-c	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P58660	uniprotkb:P61793	intact:EBI-8344379|intact:MINT-4089832|ensembl:ENSMUSP00000131003	intact:EBI-7512335|intact:MINT-1897166|uniprotkb:A2AMJ2|uniprotkb:O88584|uniprotkb:Q61130|uniprotkb:P70420|uniprotkb:P56487|ensembl:ENSMUSP00000052581|ensembl:ENSMUSP00000103197|ensembl:ENSMUSP00000103200|ensembl:ENSMUSP00000103201	psi-mi:car10_mouse(display_long)|uniprotkb:Card10(gene name)|psi-mi:Card10(display_short)|uniprotkb:Bimp1(gene name synonym)|uniprotkb:Bcl10-interacting MAGUK protein 1(gene name synonym)	psi-mi:lpar1_mouse(display_long)|uniprotkb:Gpcr26(gene name synonym)|uniprotkb:Lpa1(gene name synonym)|uniprotkb:Vzg1(gene name synonym)|uniprotkb:Edg2(gene name synonym)|uniprotkb:Lysophosphatidic acid receptor Edg-2(gene name synonym)|uniprotkb:Rec1.3(gene name synonym)|uniprotkb:VZG-1(gene name synonym)|uniprotkb:Lpar1(gene name)|psi-mi:Lpar1(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Sun et al. (2008)	pubmed:18952848|doi:10.1073/pnas.0802701105|imex:IM-22471	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15736846|imex:IM-22471-2|dip:DIP-196228E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_570929.2|dip:DIP-60780N|ensembl:ENSMUSG00000033170(gene)|ensembl:ENSMUST00000170584(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007250"(activation of NF-kappaB-inducing kinase activity)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0050700"(CARD domain binding)|go:"GO:0090051"(negative regulation of cell migration involved in sprouting angiogenesis)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|interpro:IPR001315(Caspase Recruitment)|interpro:IPR011029(DEATH-like)|interpro:IPR027417|interpro:IPR042140|mint:P58660	refseq:XP_011248230.1|refseq:XP_011248231.1|refseq:XP_011248232.1|refseq:XP_011248233.1|refseq:XP_011248234.1|refseq:XP_011248235.1|refseq:XP_011248236.1|refseq:XP_011248237.1|refseq:NP_001277415.1|refseq:NP_766577.1|refseq:NP_034466.2|ensembl:ENSMUSG00000038668(gene)|ensembl:ENSMUST00000055018(transcript)|ensembl:ENSMUST00000107571(transcript)|ensembl:ENSMUST00000107574(transcript)|ensembl:ENSMUST00000107575(transcript)|go:"GO:0001965"(G-protein alpha-subunit binding)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007189"(adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0009986"(cell surface)|go:"GO:0010942"(positive regulation of cell death)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0014003"(oligodendrocyte development)|go:"GO:0019222"(regulation of metabolic process)|go:"GO:0021549"(cerebellum development)|go:"GO:0021554"(optic nerve development)|go:"GO:0022008"(neurogenesis)|go:"GO:0022038"(corpus callosum development)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0032060"(bleb assembly)|go:"GO:0035025"(positive regulation of Rho protein signal transduction)|go:"GO:0035727"(lysophosphatidic acid binding)|go:"GO:0042552"(myelination)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043197"(dendritic spine)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043951"(negative regulation of cAMP-mediated signaling)|go:"GO:0051482"(positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0070915"(lysophosphatidic acid receptor activity)|go:"GO:0071453"(cellular response to oxygen levels)|go:"GO:0071673"(positive regulation of smooth muscle cell chemotaxis)|go:"GO:1904566"(cellular response to 1-oleoyl-sn-glycerol 3-phosphate)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002277(EDG-2 lysophosphatidic acid receptor)|interpro:IPR004065(Lysophosphatidic acid receptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|mint:P61793|reactome:R-MMU-416476|reactome:R-MMU-418594|reactome:R-MMU-419408|dip:DIP-42214N	psi-mi:"MI:0465"(dip)	comment:mint|function:Activates NF-kappa-B via BCL10 and IKK	comment:mint|function:"Receptor for lysophosphatidic acid (LPA), a mediator of diverse cellular activities. Seems to be coupled to the G(i)/G(o), G(12)/G(13), and G(q) families of heteromeric G proteins"	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2017/08/06	2017/08/10	rogid:TOvznGAAWR2wSI4PNokGO1pJY3010090	rogid:yhf0IgMrJKGv4vrABWqrgCwsHFw10090	rigid:XB41Y5cCfK1+BrPuIld1bPxRSDo	false	flag tag:n-n	ha tag:n-n	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:P58660	uniprotkb:Q91YI4	intact:EBI-8344379|intact:MINT-4089832|ensembl:ENSMUSP00000131003	intact:EBI-994161|uniprotkb:Q3TCM2|uniprotkb:Q5F2D8|uniprotkb:Q5F2E0|ensembl:ENSMUSP00000099623|ensembl:ENSMUSP00000099624	psi-mi:car10_mouse(display_long)|uniprotkb:Card10(gene name)|psi-mi:Card10(display_short)|uniprotkb:Bimp1(gene name synonym)|uniprotkb:Bcl10-interacting MAGUK protein 1(gene name synonym)	psi-mi:arrb2_mouse(display_long)|uniprotkb:Arrestin beta-2(gene name synonym)|uniprotkb:Arrb2(gene name)|psi-mi:Arrb2(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Sun et al. (2008)	pubmed:18952848|doi:10.1073/pnas.0802701105|imex:IM-22471	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15736846|imex:IM-22471-2|dip:DIP-196228E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_570929.2|dip:DIP-60780N|ensembl:ENSMUSG00000033170(gene)|ensembl:ENSMUST00000170584(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007250"(activation of NF-kappaB-inducing kinase activity)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0050700"(CARD domain binding)|go:"GO:0090051"(negative regulation of cell migration involved in sprouting angiogenesis)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|interpro:IPR001315(Caspase Recruitment)|interpro:IPR011029(DEATH-like)|interpro:IPR027417|interpro:IPR042140|mint:P58660	refseq:NP_001258287.1|refseq:NP_001258288.1|refseq:NP_001258289.1|refseq:NP_663404.1|ensembl:ENSMUSG00000060216(gene)|ensembl:ENSMUST00000102563(transcript)|ensembl:ENSMUST00000102564(transcript)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045953"(negative regulation of natural killer cell mediated cytotoxicity)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050965"(detection of temperature stimulus involved in sensory perception of pain)|go:"GO:0051019"(mitogen-activated protein kinase binding)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0051928"(positive regulation of calcium ion transport)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071889"(14-3-3 protein binding)|go:"GO:0090201"(negative regulation of release of cytochrome c from mitochondria)|go:"GO:1904037"(positive regulation of epithelial cell apoptotic process)|go:"GO:1990763"(arrestin family protein binding)|go:"GO:2000573"(positive regulation of DNA biosynthetic process)|go:"GO:2000727"(positive regulation of cardiac muscle cell differentiation)|interpro:IPR000698(Arrestin)|interpro:IPR011021(Arrestin-like, N-terminal)|interpro:IPR011022(Arrestin-like, C-terminal)|interpro:IPR014752(Arrestin, C-terminal)|interpro:IPR014753(Arrestin, N-terminal)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR017864|reactome:R-MMU-418555|reactome:R-MMU-456926|reactome:R-MMU-5099900|reactome:R-MMU-5635838|reactome:R-MMU-5674135|reactome:R-MMU-5689880|reactome:R-MMU-8856825|reactome:R-MMU-8856828|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002031"(G protein-coupled receptor internalization)|go:"GO:0002032"(desensitization of G protein-coupled receptor signaling pathway by arrestin)|go:"GO:0002092"(positive regulation of receptor internalization)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006897"(endocytosis)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007420"(brain development)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0008277"(regulation of G protein-coupled receptor signaling pathway)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015031"(protein transport)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031623"(receptor internalization)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031691"(alpha-1A adrenergic receptor binding)|go:"GO:0031692"(alpha-1B adrenergic receptor binding)|go:"GO:0031701"(angiotensin receptor binding)|go:"GO:0031702"(type 1 angiotensin receptor binding)|go:"GO:0031748"(D1 dopamine receptor binding)|go:"GO:0031762"(follicle-stimulating hormone receptor binding)|go:"GO:0031826"(type 2A serotonin receptor binding)|go:"GO:0031859"(platelet activating factor receptor binding)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032226"(positive regulation of synaptic transmission, dopaminergic)|go:"GO:0032691"(negative regulation of interleukin-1 beta production)|go:"GO:0032695"(negative regulation of interleukin-12 production)|go:"GO:0032715"(negative regulation of interleukin-6 production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034122"(negative regulation of toll-like receptor signaling pathway)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0034392"(negative regulation of smooth muscle cell apoptotic process)|go:"GO:0042699"(follicle-stimulating hormone signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043197"(dendritic spine)|go:"GO:0043422"(protein kinase B binding)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0007628"(adult walking behavior)|dip:DIP-36064N	psi-mi:"MI:0465"(dip)	comment:mint|function:Activates NF-kappa-B via BCL10 and IKK	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2017/08/06	2017/08/10	rogid:TOvznGAAWR2wSI4PNokGO1pJY3010090	rogid:0jHDvt5w5ng+xsZj2vwjhSibWeE10090	rigid:XB41Y5cCfK1+BrPuIld1bPxRSDo	false	flag tag:n-n	ha tag:n-n	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:P58660	uniprotkb:Q8BWG8	intact:EBI-8344379|intact:MINT-4089832|ensembl:ENSMUSP00000131003	intact:EBI-641778|uniprotkb:Q3UH95|uniprotkb:Q8BTJ5|ensembl:ENSMUSP00000095866	psi-mi:car10_mouse(display_long)|uniprotkb:Card10(gene name)|psi-mi:Card10(display_short)|uniprotkb:Bimp1(gene name synonym)|uniprotkb:Bcl10-interacting MAGUK protein 1(gene name synonym)	psi-mi:arrb1_mouse(display_long)|uniprotkb:Arrestin beta-1(gene name synonym)|uniprotkb:Arrb1(gene name)|psi-mi:Arrb1(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Sun et al. (2008)	pubmed:18952848|doi:10.1073/pnas.0802701105|imex:IM-22471	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15736891|imex:IM-22471-4|dip:DIP-196225E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_570929.2|dip:DIP-60780N|ensembl:ENSMUSG00000033170(gene)|ensembl:ENSMUST00000170584(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007250"(activation of NF-kappaB-inducing kinase activity)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0050700"(CARD domain binding)|go:"GO:0090051"(negative regulation of cell migration involved in sprouting angiogenesis)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|interpro:IPR001315(Caspase Recruitment)|interpro:IPR011029(DEATH-like)|interpro:IPR027417|interpro:IPR042140|mint:P58660	refseq:NP_796205.1|refseq:NP_835738.1|dip:DIP-49444N|ensembl:ENSMUSG00000018909(gene)|ensembl:ENSMUST00000098266(transcript)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0000785"(chromatin)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002031"(G protein-coupled receptor internalization)|go:"GO:0002092"(positive regulation of receptor internalization)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005159"(insulin-like growth factor receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007602"(phototransduction)|go:"GO:0008277"(regulation of G protein-coupled receptor signaling pathway)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015031"(protein transport)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0019899"(enzyme binding)|go:"GO:0030276"(clathrin binding)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0031143"(pseudopodium)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031434"(mitogen-activated protein kinase kinase binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031691"(alpha-1A adrenergic receptor binding)|go:"GO:0031692"(alpha-1B adrenergic receptor binding)|go:"GO:0031701"(angiotensin receptor binding)|go:"GO:0031762"(follicle-stimulating hormone receptor binding)|go:"GO:0031896"(V2 vasopressin receptor binding)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032715"(negative regulation of interleukin-6 production)|go:"GO:0032717"(negative regulation of interleukin-8 production)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0034393"(positive regulation of smooth muscle cell apoptotic process)|go:"GO:0035025"(positive regulation of Rho protein signal transduction)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0035612"(AP-2 adaptor complex binding)|go:"GO:0035615"(clathrin adaptor activity)|go:"GO:0035774"(positive regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0042699"(follicle-stimulating hormone signaling pathway)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043027"(cysteine-type endopeptidase inhibitor activity involved in apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043149"(stress fiber assembly)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043197"(dendritic spine)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045309"(protein phosphorylated amino acid binding)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0090240"(positive regulation of histone H4 acetylation)|go:"GO:1990763"(arrestin family protein binding)|interpro:IPR000698(Arrestin)|interpro:IPR011021(Arrestin-like, N-terminal)|interpro:IPR011022(Arrestin-like, C-terminal)|interpro:IPR014752(Arrestin, C-terminal)|interpro:IPR014753(Arrestin, N-terminal)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR017864|mint:Q8BWG8|reactome:R-MMU-432720|reactome:R-MMU-432722|reactome:R-MMU-456926|reactome:R-MMU-5635838|reactome:R-MMU-5674135|reactome:R-MMU-5689880|reactome:R-MMU-8856825|reactome:R-MMU-8856828|reactome:R-MMU-418555	psi-mi:"MI:0465"(dip)	comment:mint|function:Activates NF-kappa-B via BCL10 and IKK	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse)|taxid:10090(Mus musculus)	-	2017/08/06	2017/08/10	rogid:TOvznGAAWR2wSI4PNokGO1pJY3010090	rogid:QnjSypgRI1Aym+xBu3vpHxVSAD010090	rigid:x5CSyvOQ1N/RG5wdSeKT4+1QYVY	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P58660	uniprotkb:Q91YI4	intact:EBI-8344379|intact:MINT-4089832|ensembl:ENSMUSP00000131003	intact:EBI-994161|uniprotkb:Q3TCM2|uniprotkb:Q5F2D8|uniprotkb:Q5F2E0|ensembl:ENSMUSP00000099623|ensembl:ENSMUSP00000099624	psi-mi:car10_mouse(display_long)|uniprotkb:Card10(gene name)|psi-mi:Card10(display_short)|uniprotkb:Bimp1(gene name synonym)|uniprotkb:Bcl10-interacting MAGUK protein 1(gene name synonym)	psi-mi:arrb2_mouse(display_long)|uniprotkb:Arrestin beta-2(gene name synonym)|uniprotkb:Arrb2(gene name)|psi-mi:Arrb2(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Sun et al. (2008)	pubmed:18952848|doi:10.1073/pnas.0802701105|imex:IM-22471	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15736908|imex:IM-22471-5|dip:DIP-196226E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_570929.2|dip:DIP-60780N|ensembl:ENSMUSG00000033170(gene)|ensembl:ENSMUST00000170584(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007250"(activation of NF-kappaB-inducing kinase activity)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0050700"(CARD domain binding)|go:"GO:0090051"(negative regulation of cell migration involved in sprouting angiogenesis)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|interpro:IPR001315(Caspase Recruitment)|interpro:IPR011029(DEATH-like)|interpro:IPR027417|interpro:IPR042140|mint:P58660	refseq:NP_001258287.1|refseq:NP_001258288.1|refseq:NP_001258289.1|refseq:NP_663404.1|ensembl:ENSMUSG00000060216(gene)|ensembl:ENSMUST00000102563(transcript)|ensembl:ENSMUST00000102564(transcript)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045953"(negative regulation of natural killer cell mediated cytotoxicity)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050965"(detection of temperature stimulus involved in sensory perception of pain)|go:"GO:0051019"(mitogen-activated protein kinase binding)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0051928"(positive regulation of calcium ion transport)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071889"(14-3-3 protein binding)|go:"GO:0090201"(negative regulation of release of cytochrome c from mitochondria)|go:"GO:1904037"(positive regulation of epithelial cell apoptotic process)|go:"GO:1990763"(arrestin family protein binding)|go:"GO:2000573"(positive regulation of DNA biosynthetic process)|go:"GO:2000727"(positive regulation of cardiac muscle cell differentiation)|interpro:IPR000698(Arrestin)|interpro:IPR011021(Arrestin-like, N-terminal)|interpro:IPR011022(Arrestin-like, C-terminal)|interpro:IPR014752(Arrestin, C-terminal)|interpro:IPR014753(Arrestin, N-terminal)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR017864|reactome:R-MMU-418555|reactome:R-MMU-456926|reactome:R-MMU-5099900|reactome:R-MMU-5635838|reactome:R-MMU-5674135|reactome:R-MMU-5689880|reactome:R-MMU-8856825|reactome:R-MMU-8856828|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002031"(G protein-coupled receptor internalization)|go:"GO:0002032"(desensitization of G protein-coupled receptor signaling pathway by arrestin)|go:"GO:0002092"(positive regulation of receptor internalization)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006897"(endocytosis)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007420"(brain development)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0008277"(regulation of G protein-coupled receptor signaling pathway)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015031"(protein transport)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031623"(receptor internalization)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031691"(alpha-1A adrenergic receptor binding)|go:"GO:0031692"(alpha-1B adrenergic receptor binding)|go:"GO:0031701"(angiotensin receptor binding)|go:"GO:0031702"(type 1 angiotensin receptor binding)|go:"GO:0031748"(D1 dopamine receptor binding)|go:"GO:0031762"(follicle-stimulating hormone receptor binding)|go:"GO:0031826"(type 2A serotonin receptor binding)|go:"GO:0031859"(platelet activating factor receptor binding)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032226"(positive regulation of synaptic transmission, dopaminergic)|go:"GO:0032691"(negative regulation of interleukin-1 beta production)|go:"GO:0032695"(negative regulation of interleukin-12 production)|go:"GO:0032715"(negative regulation of interleukin-6 production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034122"(negative regulation of toll-like receptor signaling pathway)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0034392"(negative regulation of smooth muscle cell apoptotic process)|go:"GO:0042699"(follicle-stimulating hormone signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043197"(dendritic spine)|go:"GO:0043422"(protein kinase B binding)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0007628"(adult walking behavior)|dip:DIP-36064N	psi-mi:"MI:0465"(dip)	comment:mint|function:Activates NF-kappa-B via BCL10 and IKK	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2017/08/06	2017/08/10	rogid:TOvznGAAWR2wSI4PNokGO1pJY3010090	rogid:0jHDvt5w5ng+xsZj2vwjhSibWeE10090	rigid:+rrQbZro/dixYt4/gRutBeIFN1o	false	ha tag:n-n	sufficient binding region:1-320|sufficient binding region:60-410|flag tag:n-n	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:P58660	uniprotkb:Q8BWG8	intact:EBI-8344379|intact:MINT-4089832|ensembl:ENSMUSP00000131003	intact:EBI-641778|uniprotkb:Q3UH95|uniprotkb:Q8BTJ5|ensembl:ENSMUSP00000095866	psi-mi:car10_mouse(display_long)|uniprotkb:Card10(gene name)|psi-mi:Card10(display_short)|uniprotkb:Bimp1(gene name synonym)|uniprotkb:Bcl10-interacting MAGUK protein 1(gene name synonym)	psi-mi:arrb1_mouse(display_long)|uniprotkb:Arrestin beta-1(gene name synonym)|uniprotkb:Arrb1(gene name)|psi-mi:Arrb1(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Sun et al. (2008)	pubmed:18952848|doi:10.1073/pnas.0802701105|imex:IM-22471	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15736933|imex:IM-22471-6|dip:DIP-196225E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_570929.2|dip:DIP-60780N|ensembl:ENSMUSG00000033170(gene)|ensembl:ENSMUST00000170584(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007250"(activation of NF-kappaB-inducing kinase activity)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0050700"(CARD domain binding)|go:"GO:0090051"(negative regulation of cell migration involved in sprouting angiogenesis)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|interpro:IPR001315(Caspase Recruitment)|interpro:IPR011029(DEATH-like)|interpro:IPR027417|interpro:IPR042140|mint:P58660	refseq:NP_796205.1|refseq:NP_835738.1|dip:DIP-49444N|ensembl:ENSMUSG00000018909(gene)|ensembl:ENSMUST00000098266(transcript)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0000785"(chromatin)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002031"(G protein-coupled receptor internalization)|go:"GO:0002092"(positive regulation of receptor internalization)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005159"(insulin-like growth factor receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007602"(phototransduction)|go:"GO:0008277"(regulation of G protein-coupled receptor signaling pathway)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015031"(protein transport)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0019899"(enzyme binding)|go:"GO:0030276"(clathrin binding)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0031143"(pseudopodium)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031434"(mitogen-activated protein kinase kinase binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031691"(alpha-1A adrenergic receptor binding)|go:"GO:0031692"(alpha-1B adrenergic receptor binding)|go:"GO:0031701"(angiotensin receptor binding)|go:"GO:0031762"(follicle-stimulating hormone receptor binding)|go:"GO:0031896"(V2 vasopressin receptor binding)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032715"(negative regulation of interleukin-6 production)|go:"GO:0032717"(negative regulation of interleukin-8 production)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0034393"(positive regulation of smooth muscle cell apoptotic process)|go:"GO:0035025"(positive regulation of Rho protein signal transduction)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0035612"(AP-2 adaptor complex binding)|go:"GO:0035615"(clathrin adaptor activity)|go:"GO:0035774"(positive regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0042699"(follicle-stimulating hormone signaling pathway)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043027"(cysteine-type endopeptidase inhibitor activity involved in apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043149"(stress fiber assembly)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043197"(dendritic spine)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045309"(protein phosphorylated amino acid binding)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0090240"(positive regulation of histone H4 acetylation)|go:"GO:1990763"(arrestin family protein binding)|interpro:IPR000698(Arrestin)|interpro:IPR011021(Arrestin-like, N-terminal)|interpro:IPR011022(Arrestin-like, C-terminal)|interpro:IPR014752(Arrestin, C-terminal)|interpro:IPR014753(Arrestin, N-terminal)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR017864|mint:Q8BWG8|reactome:R-MMU-432720|reactome:R-MMU-432722|reactome:R-MMU-456926|reactome:R-MMU-5635838|reactome:R-MMU-5674135|reactome:R-MMU-5689880|reactome:R-MMU-8856825|reactome:R-MMU-8856828|reactome:R-MMU-418555	psi-mi:"MI:0465"(dip)	comment:mint|function:Activates NF-kappa-B via BCL10 and IKK	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2017/08/06	2017/08/10	rogid:TOvznGAAWR2wSI4PNokGO1pJY3010090	rogid:QnjSypgRI1Aym+xBu3vpHxVSAD010090	rigid:x5CSyvOQ1N/RG5wdSeKT4+1QYVY	false	ha tag:c-c	flag tag:c-c	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P58660	uniprotkb:Q91YI4	intact:EBI-8344379|intact:MINT-4089832|ensembl:ENSMUSP00000131003	intact:EBI-994161|uniprotkb:Q3TCM2|uniprotkb:Q5F2D8|uniprotkb:Q5F2E0|ensembl:ENSMUSP00000099623|ensembl:ENSMUSP00000099624	psi-mi:car10_mouse(display_long)|uniprotkb:Card10(gene name)|psi-mi:Card10(display_short)|uniprotkb:Bimp1(gene name synonym)|uniprotkb:Bcl10-interacting MAGUK protein 1(gene name synonym)	psi-mi:arrb2_mouse(display_long)|uniprotkb:Arrestin beta-2(gene name synonym)|uniprotkb:Arrb2(gene name)|psi-mi:Arrb2(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Sun et al. (2008)	pubmed:18952848|doi:10.1073/pnas.0802701105|imex:IM-22471	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15736992|imex:IM-22471-9|dip:DIP-196226E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_570929.2|dip:DIP-60780N|ensembl:ENSMUSG00000033170(gene)|ensembl:ENSMUST00000170584(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007250"(activation of NF-kappaB-inducing kinase activity)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0050700"(CARD domain binding)|go:"GO:0090051"(negative regulation of cell migration involved in sprouting angiogenesis)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|interpro:IPR001315(Caspase Recruitment)|interpro:IPR011029(DEATH-like)|interpro:IPR027417|interpro:IPR042140|mint:P58660	refseq:NP_001258287.1|refseq:NP_001258288.1|refseq:NP_001258289.1|refseq:NP_663404.1|ensembl:ENSMUSG00000060216(gene)|ensembl:ENSMUST00000102563(transcript)|ensembl:ENSMUST00000102564(transcript)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045953"(negative regulation of natural killer cell mediated cytotoxicity)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050965"(detection of temperature stimulus involved in sensory perception of pain)|go:"GO:0051019"(mitogen-activated protein kinase binding)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0051928"(positive regulation of calcium ion transport)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071889"(14-3-3 protein binding)|go:"GO:0090201"(negative regulation of release of cytochrome c from mitochondria)|go:"GO:1904037"(positive regulation of epithelial cell apoptotic process)|go:"GO:1990763"(arrestin family protein binding)|go:"GO:2000573"(positive regulation of DNA biosynthetic process)|go:"GO:2000727"(positive regulation of cardiac muscle cell differentiation)|interpro:IPR000698(Arrestin)|interpro:IPR011021(Arrestin-like, N-terminal)|interpro:IPR011022(Arrestin-like, C-terminal)|interpro:IPR014752(Arrestin, C-terminal)|interpro:IPR014753(Arrestin, N-terminal)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR017864|reactome:R-MMU-418555|reactome:R-MMU-456926|reactome:R-MMU-5099900|reactome:R-MMU-5635838|reactome:R-MMU-5674135|reactome:R-MMU-5689880|reactome:R-MMU-8856825|reactome:R-MMU-8856828|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002031"(G protein-coupled receptor internalization)|go:"GO:0002032"(desensitization of G protein-coupled receptor signaling pathway by arrestin)|go:"GO:0002092"(positive regulation of receptor internalization)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006897"(endocytosis)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007420"(brain development)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0008277"(regulation of G protein-coupled receptor signaling pathway)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015031"(protein transport)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031623"(receptor internalization)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031691"(alpha-1A adrenergic receptor binding)|go:"GO:0031692"(alpha-1B adrenergic receptor binding)|go:"GO:0031701"(angiotensin receptor binding)|go:"GO:0031702"(type 1 angiotensin receptor binding)|go:"GO:0031748"(D1 dopamine receptor binding)|go:"GO:0031762"(follicle-stimulating hormone receptor binding)|go:"GO:0031826"(type 2A serotonin receptor binding)|go:"GO:0031859"(platelet activating factor receptor binding)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032226"(positive regulation of synaptic transmission, dopaminergic)|go:"GO:0032691"(negative regulation of interleukin-1 beta production)|go:"GO:0032695"(negative regulation of interleukin-12 production)|go:"GO:0032715"(negative regulation of interleukin-6 production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034122"(negative regulation of toll-like receptor signaling pathway)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0034392"(negative regulation of smooth muscle cell apoptotic process)|go:"GO:0042699"(follicle-stimulating hormone signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043197"(dendritic spine)|go:"GO:0043422"(protein kinase B binding)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0007628"(adult walking behavior)|dip:DIP-36064N	psi-mi:"MI:0465"(dip)	comment:mint|function:Activates NF-kappa-B via BCL10 and IKK	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2017/08/06	2017/08/10	rogid:TOvznGAAWR2wSI4PNokGO1pJY3010090	rogid:0jHDvt5w5ng+xsZj2vwjhSibWeE10090	rigid:+rrQbZro/dixYt4/gRutBeIFN1o	false	flag tag:n-n	ha tag:n-n	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:P58660	uniprotkb:Q91YI4	intact:EBI-8344379|intact:MINT-4089832|ensembl:ENSMUSP00000131003	intact:EBI-994161|uniprotkb:Q3TCM2|uniprotkb:Q5F2D8|uniprotkb:Q5F2E0|ensembl:ENSMUSP00000099623|ensembl:ENSMUSP00000099624	psi-mi:car10_mouse(display_long)|uniprotkb:Card10(gene name)|psi-mi:Card10(display_short)|uniprotkb:Bimp1(gene name synonym)|uniprotkb:Bcl10-interacting MAGUK protein 1(gene name synonym)	psi-mi:arrb2_mouse(display_long)|uniprotkb:Arrestin beta-2(gene name synonym)|uniprotkb:Arrb2(gene name)|psi-mi:Arrb2(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Sun et al. (2008)	pubmed:18952848|doi:10.1073/pnas.0802701105|imex:IM-22471	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15736971|imex:IM-22471-8|dip:DIP-196226E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_570929.2|dip:DIP-60780N|ensembl:ENSMUSG00000033170(gene)|ensembl:ENSMUST00000170584(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007250"(activation of NF-kappaB-inducing kinase activity)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0050700"(CARD domain binding)|go:"GO:0090051"(negative regulation of cell migration involved in sprouting angiogenesis)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|interpro:IPR001315(Caspase Recruitment)|interpro:IPR011029(DEATH-like)|interpro:IPR027417|interpro:IPR042140|mint:P58660	refseq:NP_001258287.1|refseq:NP_001258288.1|refseq:NP_001258289.1|refseq:NP_663404.1|ensembl:ENSMUSG00000060216(gene)|ensembl:ENSMUST00000102563(transcript)|ensembl:ENSMUST00000102564(transcript)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045953"(negative regulation of natural killer cell mediated cytotoxicity)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050965"(detection of temperature stimulus involved in sensory perception of pain)|go:"GO:0051019"(mitogen-activated protein kinase binding)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0051928"(positive regulation of calcium ion transport)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071889"(14-3-3 protein binding)|go:"GO:0090201"(negative regulation of release of cytochrome c from mitochondria)|go:"GO:1904037"(positive regulation of epithelial cell apoptotic process)|go:"GO:1990763"(arrestin family protein binding)|go:"GO:2000573"(positive regulation of DNA biosynthetic process)|go:"GO:2000727"(positive regulation of cardiac muscle cell differentiation)|interpro:IPR000698(Arrestin)|interpro:IPR011021(Arrestin-like, N-terminal)|interpro:IPR011022(Arrestin-like, C-terminal)|interpro:IPR014752(Arrestin, C-terminal)|interpro:IPR014753(Arrestin, N-terminal)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR017864|reactome:R-MMU-418555|reactome:R-MMU-456926|reactome:R-MMU-5099900|reactome:R-MMU-5635838|reactome:R-MMU-5674135|reactome:R-MMU-5689880|reactome:R-MMU-8856825|reactome:R-MMU-8856828|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002031"(G protein-coupled receptor internalization)|go:"GO:0002032"(desensitization of G protein-coupled receptor signaling pathway by arrestin)|go:"GO:0002092"(positive regulation of receptor internalization)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006897"(endocytosis)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007420"(brain development)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0008277"(regulation of G protein-coupled receptor signaling pathway)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015031"(protein transport)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031623"(receptor internalization)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031691"(alpha-1A adrenergic receptor binding)|go:"GO:0031692"(alpha-1B adrenergic receptor binding)|go:"GO:0031701"(angiotensin receptor binding)|go:"GO:0031702"(type 1 angiotensin receptor binding)|go:"GO:0031748"(D1 dopamine receptor binding)|go:"GO:0031762"(follicle-stimulating hormone receptor binding)|go:"GO:0031826"(type 2A serotonin receptor binding)|go:"GO:0031859"(platelet activating factor receptor binding)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032226"(positive regulation of synaptic transmission, dopaminergic)|go:"GO:0032691"(negative regulation of interleukin-1 beta production)|go:"GO:0032695"(negative regulation of interleukin-12 production)|go:"GO:0032715"(negative regulation of interleukin-6 production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034122"(negative regulation of toll-like receptor signaling pathway)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0034392"(negative regulation of smooth muscle cell apoptotic process)|go:"GO:0042699"(follicle-stimulating hormone signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043197"(dendritic spine)|go:"GO:0043422"(protein kinase B binding)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0007628"(adult walking behavior)|dip:DIP-36064N	psi-mi:"MI:0465"(dip)	comment:mint|function:Activates NF-kappa-B via BCL10 and IKK	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2017/08/06	2017/08/10	rogid:TOvznGAAWR2wSI4PNokGO1pJY3010090	rogid:0jHDvt5w5ng+xsZj2vwjhSibWeE10090	rigid:+rrQbZro/dixYt4/gRutBeIFN1o	false	ha tag:c-c	flag tag:c-c	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P58660	uniprotkb:Q91YI4	intact:EBI-8344379|intact:MINT-4089832|ensembl:ENSMUSP00000131003	intact:EBI-994161|uniprotkb:Q3TCM2|uniprotkb:Q5F2D8|uniprotkb:Q5F2E0|ensembl:ENSMUSP00000099623|ensembl:ENSMUSP00000099624	psi-mi:car10_mouse(display_long)|uniprotkb:Card10(gene name)|psi-mi:Card10(display_short)|uniprotkb:Bimp1(gene name synonym)|uniprotkb:Bcl10-interacting MAGUK protein 1(gene name synonym)	psi-mi:arrb2_mouse(display_long)|uniprotkb:Arrestin beta-2(gene name synonym)|uniprotkb:Arrb2(gene name)|psi-mi:Arrb2(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Sun et al. (2008)	pubmed:18952848|doi:10.1073/pnas.0802701105|imex:IM-22471	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15736954|imex:IM-22471-7|dip:DIP-196226E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_570929.2|dip:DIP-60780N|ensembl:ENSMUSG00000033170(gene)|ensembl:ENSMUST00000170584(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007250"(activation of NF-kappaB-inducing kinase activity)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0050700"(CARD domain binding)|go:"GO:0090051"(negative regulation of cell migration involved in sprouting angiogenesis)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|interpro:IPR001315(Caspase Recruitment)|interpro:IPR011029(DEATH-like)|interpro:IPR027417|interpro:IPR042140|mint:P58660	refseq:NP_001258287.1|refseq:NP_001258288.1|refseq:NP_001258289.1|refseq:NP_663404.1|ensembl:ENSMUSG00000060216(gene)|ensembl:ENSMUST00000102563(transcript)|ensembl:ENSMUST00000102564(transcript)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045953"(negative regulation of natural killer cell mediated cytotoxicity)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050965"(detection of temperature stimulus involved in sensory perception of pain)|go:"GO:0051019"(mitogen-activated protein kinase binding)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0051928"(positive regulation of calcium ion transport)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071889"(14-3-3 protein binding)|go:"GO:0090201"(negative regulation of release of cytochrome c from mitochondria)|go:"GO:1904037"(positive regulation of epithelial cell apoptotic process)|go:"GO:1990763"(arrestin family protein binding)|go:"GO:2000573"(positive regulation of DNA biosynthetic process)|go:"GO:2000727"(positive regulation of cardiac muscle cell differentiation)|interpro:IPR000698(Arrestin)|interpro:IPR011021(Arrestin-like, N-terminal)|interpro:IPR011022(Arrestin-like, C-terminal)|interpro:IPR014752(Arrestin, C-terminal)|interpro:IPR014753(Arrestin, N-terminal)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR017864|reactome:R-MMU-418555|reactome:R-MMU-456926|reactome:R-MMU-5099900|reactome:R-MMU-5635838|reactome:R-MMU-5674135|reactome:R-MMU-5689880|reactome:R-MMU-8856825|reactome:R-MMU-8856828|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002031"(G protein-coupled receptor internalization)|go:"GO:0002032"(desensitization of G protein-coupled receptor signaling pathway by arrestin)|go:"GO:0002092"(positive regulation of receptor internalization)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006897"(endocytosis)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007420"(brain development)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0008277"(regulation of G protein-coupled receptor signaling pathway)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015031"(protein transport)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031623"(receptor internalization)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031691"(alpha-1A adrenergic receptor binding)|go:"GO:0031692"(alpha-1B adrenergic receptor binding)|go:"GO:0031701"(angiotensin receptor binding)|go:"GO:0031702"(type 1 angiotensin receptor binding)|go:"GO:0031748"(D1 dopamine receptor binding)|go:"GO:0031762"(follicle-stimulating hormone receptor binding)|go:"GO:0031826"(type 2A serotonin receptor binding)|go:"GO:0031859"(platelet activating factor receptor binding)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032226"(positive regulation of synaptic transmission, dopaminergic)|go:"GO:0032691"(negative regulation of interleukin-1 beta production)|go:"GO:0032695"(negative regulation of interleukin-12 production)|go:"GO:0032715"(negative regulation of interleukin-6 production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034122"(negative regulation of toll-like receptor signaling pathway)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0034392"(negative regulation of smooth muscle cell apoptotic process)|go:"GO:0042699"(follicle-stimulating hormone signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043197"(dendritic spine)|go:"GO:0043422"(protein kinase B binding)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0007628"(adult walking behavior)|dip:DIP-36064N	psi-mi:"MI:0465"(dip)	comment:mint|function:Activates NF-kappa-B via BCL10 and IKK	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse)|taxid:10090(Mus musculus)	-	2017/08/06	2017/08/10	rogid:TOvznGAAWR2wSI4PNokGO1pJY3010090	rogid:0jHDvt5w5ng+xsZj2vwjhSibWeE10090	rigid:+rrQbZro/dixYt4/gRutBeIFN1o	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P58660	uniprotkb:Q91YI4	intact:EBI-8344379|intact:MINT-4089832|ensembl:ENSMUSP00000131003	intact:EBI-994161|uniprotkb:Q3TCM2|uniprotkb:Q5F2D8|uniprotkb:Q5F2E0|ensembl:ENSMUSP00000099623|ensembl:ENSMUSP00000099624	psi-mi:car10_mouse(display_long)|uniprotkb:Card10(gene name)|psi-mi:Card10(display_short)|uniprotkb:Bimp1(gene name synonym)|uniprotkb:Bcl10-interacting MAGUK protein 1(gene name synonym)	psi-mi:arrb2_mouse(display_long)|uniprotkb:Arrestin beta-2(gene name synonym)|uniprotkb:Arrb2(gene name)|psi-mi:Arrb2(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Sun et al. (2008)	pubmed:18952848|doi:10.1073/pnas.0802701105|imex:IM-22471	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15737013|imex:IM-22471-10|dip:DIP-196226E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_570929.2|dip:DIP-60780N|ensembl:ENSMUSG00000033170(gene)|ensembl:ENSMUST00000170584(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007250"(activation of NF-kappaB-inducing kinase activity)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0050700"(CARD domain binding)|go:"GO:0090051"(negative regulation of cell migration involved in sprouting angiogenesis)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|interpro:IPR001315(Caspase Recruitment)|interpro:IPR011029(DEATH-like)|interpro:IPR027417|interpro:IPR042140|mint:P58660	refseq:NP_001258287.1|refseq:NP_001258288.1|refseq:NP_001258289.1|refseq:NP_663404.1|ensembl:ENSMUSG00000060216(gene)|ensembl:ENSMUST00000102563(transcript)|ensembl:ENSMUST00000102564(transcript)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045953"(negative regulation of natural killer cell mediated cytotoxicity)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050965"(detection of temperature stimulus involved in sensory perception of pain)|go:"GO:0051019"(mitogen-activated protein kinase binding)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0051928"(positive regulation of calcium ion transport)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071889"(14-3-3 protein binding)|go:"GO:0090201"(negative regulation of release of cytochrome c from mitochondria)|go:"GO:1904037"(positive regulation of epithelial cell apoptotic process)|go:"GO:1990763"(arrestin family protein binding)|go:"GO:2000573"(positive regulation of DNA biosynthetic process)|go:"GO:2000727"(positive regulation of cardiac muscle cell differentiation)|interpro:IPR000698(Arrestin)|interpro:IPR011021(Arrestin-like, N-terminal)|interpro:IPR011022(Arrestin-like, C-terminal)|interpro:IPR014752(Arrestin, C-terminal)|interpro:IPR014753(Arrestin, N-terminal)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR017864|reactome:R-MMU-418555|reactome:R-MMU-456926|reactome:R-MMU-5099900|reactome:R-MMU-5635838|reactome:R-MMU-5674135|reactome:R-MMU-5689880|reactome:R-MMU-8856825|reactome:R-MMU-8856828|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002031"(G protein-coupled receptor internalization)|go:"GO:0002032"(desensitization of G protein-coupled receptor signaling pathway by arrestin)|go:"GO:0002092"(positive regulation of receptor internalization)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006897"(endocytosis)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007420"(brain development)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0008277"(regulation of G protein-coupled receptor signaling pathway)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015031"(protein transport)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031623"(receptor internalization)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031691"(alpha-1A adrenergic receptor binding)|go:"GO:0031692"(alpha-1B adrenergic receptor binding)|go:"GO:0031701"(angiotensin receptor binding)|go:"GO:0031702"(type 1 angiotensin receptor binding)|go:"GO:0031748"(D1 dopamine receptor binding)|go:"GO:0031762"(follicle-stimulating hormone receptor binding)|go:"GO:0031826"(type 2A serotonin receptor binding)|go:"GO:0031859"(platelet activating factor receptor binding)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032226"(positive regulation of synaptic transmission, dopaminergic)|go:"GO:0032691"(negative regulation of interleukin-1 beta production)|go:"GO:0032695"(negative regulation of interleukin-12 production)|go:"GO:0032715"(negative regulation of interleukin-6 production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034122"(negative regulation of toll-like receptor signaling pathway)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0034392"(negative regulation of smooth muscle cell apoptotic process)|go:"GO:0042699"(follicle-stimulating hormone signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043197"(dendritic spine)|go:"GO:0043422"(protein kinase B binding)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0007628"(adult walking behavior)|dip:DIP-36064N	psi-mi:"MI:0465"(dip)	comment:mint|function:Activates NF-kappa-B via BCL10 and IKK	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2017/08/06	2017/08/10	rogid:TOvznGAAWR2wSI4PNokGO1pJY3010090	rogid:0jHDvt5w5ng+xsZj2vwjhSibWeE10090	rigid:+rrQbZro/dixYt4/gRutBeIFN1o	false	ha tag:c-c	flag tag:c-c	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)