#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q9ES67	uniprotkb:P27601	intact:EBI-15735216	intact:EBI-2255627|uniprotkb:Q6PF99|ensembl:ENSMUSP00000020930	psi-mi:arhgb_rat(display_long)|uniprotkb:Arhgef11(gene name)|psi-mi:Arhgef11(display_short)|uniprotkb:RhoGEF glutamate transport modulator GTRAP48(gene name synonym)	psi-mi:gna13_mouse(display_long)|uniprotkb:Gna-13(gene name synonym)|uniprotkb:Gna13(gene name)|psi-mi:Gna13(display_short)	psi-mi:"MI:0114"(x-ray crystallography)	Chen et al. (2008)	pubmed:18940608|doi:10.1016/j.str.2008.07.009|imex:IM-9487	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15735246|imex:IM-9487-3|dip:DIP-88144E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0001505"(regulation of neurotransmitter levels)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001331(Guanine-nucleotide dissociation stimulator, CDC24, conserved site)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015212(Regulator of G protein signalling-like fold)|interpro:IPR016137(Regulator of G protein signalling superfamily)|interpro:IPR032919|interpro:IPR035899|interpro:IPR036034|interpro:IPR036305|interpro:IPR037803|interpro:IPR037889|interpro:IPR041020|rcsb pdb:3CX6|rcsb pdb:3CX7|rcsb pdb:3CX8|reactome:R-RNO-193648|reactome:R-RNO-416572|reactome:R-RNO-8980692|reactome:R-RNO-9013026|reactome:R-RNO-9013106|reactome:R-RNO-9013148|reactome:R-RNO-9013149|rgd:619705|refseq:NP_076472.1|dip:DIP-46242N|reactome:R-RNO-416482	refseq:NP_034433.3|dip:DIP-46241N|ensembl:ENSMUSG00000020611(gene)|ensembl:ENSMUST00000020930(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001569"(branching involved in blood vessel morphogenesis)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005834"(heterotrimeric G-protein complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0007189"(adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0030154"(cell differentiation)|go:"GO:0030168"(platelet activation)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031526"(brush border membrane)|go:"GO:0031584"(activation of phospholipase D activity)|go:"GO:0031683"(G-protein beta/gamma-subunit complex binding)|go:"GO:0031752"(D5 dopamine receptor binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042470"(melanosome)|go:"GO:0046872"(metal ion binding)|go:"GO:1904706"(negative regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1904753"(negative regulation of vascular associated smooth muscle cell migration)|interpro:IPR000469(G-protein alpha subunit, group 12)|interpro:IPR001019("Guanine nucleotide binding protein (G-protein), alpha subunit")|interpro:IPR011025(G protein alpha subunit, helical insertion)|interpro:IPR027417|mint:P27601|rcsb pdb:1SHZ|rcsb pdb:1ZCB|rcsb pdb:3AB3|rcsb pdb:3CX6|rcsb pdb:3CX7|rcsb pdb:3CX8|reactome:R-MMU-193648|reactome:R-MMU-416482|reactome:R-MMU-428930|reactome:R-MMU-456926|reactome:R-MMU-9013148|reactome:R-MMU-9013149	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/06	2017/08/10	rogid:YopqNCbuKyqNJowlb592y7ukq9Q10116	rogid:lG592gVBa3xiDv+BVn5SF8Rj/pA10090	rigid:kBYpr15TKMuHjS1+i5eTRSM0Mlo	false	binding-associated region:307-508	binding-associated region:41-377	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9ES67	uniprotkb:P27601	intact:EBI-15735216	intact:EBI-2255627|uniprotkb:Q6PF99|ensembl:ENSMUSP00000020930	psi-mi:arhgb_rat(display_long)|uniprotkb:Arhgef11(gene name)|psi-mi:Arhgef11(display_short)|uniprotkb:RhoGEF glutamate transport modulator GTRAP48(gene name synonym)	psi-mi:gna13_mouse(display_long)|uniprotkb:Gna-13(gene name synonym)|uniprotkb:Gna13(gene name)|psi-mi:Gna13(display_short)	psi-mi:"MI:0071"(molecular sieving)	Chen et al. (2008)	pubmed:18940608|doi:10.1016/j.str.2008.07.009|imex:IM-9487	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15735267|imex:IM-9487-1|dip:DIP-88144E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0001505"(regulation of neurotransmitter levels)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001331(Guanine-nucleotide dissociation stimulator, CDC24, conserved site)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015212(Regulator of G protein signalling-like fold)|interpro:IPR016137(Regulator of G protein signalling superfamily)|interpro:IPR032919|interpro:IPR035899|interpro:IPR036034|interpro:IPR036305|interpro:IPR037803|interpro:IPR037889|interpro:IPR041020|rcsb pdb:3CX6|rcsb pdb:3CX7|rcsb pdb:3CX8|reactome:R-RNO-193648|reactome:R-RNO-416572|reactome:R-RNO-8980692|reactome:R-RNO-9013026|reactome:R-RNO-9013106|reactome:R-RNO-9013148|reactome:R-RNO-9013149|rgd:619705|refseq:NP_076472.1|dip:DIP-46242N|reactome:R-RNO-416482	refseq:NP_034433.3|dip:DIP-46241N|ensembl:ENSMUSG00000020611(gene)|ensembl:ENSMUST00000020930(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001569"(branching involved in blood vessel morphogenesis)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005834"(heterotrimeric G-protein complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0007189"(adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0030154"(cell differentiation)|go:"GO:0030168"(platelet activation)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031526"(brush border membrane)|go:"GO:0031584"(activation of phospholipase D activity)|go:"GO:0031683"(G-protein beta/gamma-subunit complex binding)|go:"GO:0031752"(D5 dopamine receptor binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042470"(melanosome)|go:"GO:0046872"(metal ion binding)|go:"GO:1904706"(negative regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1904753"(negative regulation of vascular associated smooth muscle cell migration)|interpro:IPR000469(G-protein alpha subunit, group 12)|interpro:IPR001019("Guanine nucleotide binding protein (G-protein), alpha subunit")|interpro:IPR011025(G protein alpha subunit, helical insertion)|interpro:IPR027417|mint:P27601|rcsb pdb:1SHZ|rcsb pdb:1ZCB|rcsb pdb:3AB3|rcsb pdb:3CX6|rcsb pdb:3CX7|rcsb pdb:3CX8|reactome:R-MMU-193648|reactome:R-MMU-416482|reactome:R-MMU-428930|reactome:R-MMU-456926|reactome:R-MMU-9013148|reactome:R-MMU-9013149	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/06	2017/08/10	rogid:YopqNCbuKyqNJowlb592y7ukq9Q10116	rogid:lG592gVBa3xiDv+BVn5SF8Rj/pA10090	rigid:kBYpr15TKMuHjS1+i5eTRSM0Mlo	false	binding-associated region:307-508	binding-associated region:41-377	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9ES67	uniprotkb:P27601	intact:EBI-15735216	intact:EBI-2255627|uniprotkb:Q6PF99|ensembl:ENSMUSP00000020930	psi-mi:arhgb_rat(display_long)|uniprotkb:Arhgef11(gene name)|psi-mi:Arhgef11(display_short)|uniprotkb:RhoGEF glutamate transport modulator GTRAP48(gene name synonym)	psi-mi:gna13_mouse(display_long)|uniprotkb:Gna-13(gene name synonym)|uniprotkb:Gna13(gene name)|psi-mi:Gna13(display_short)	psi-mi:"MI:0065"(isothermal titration calorimetry)	Chen et al. (2008)	pubmed:18940608|doi:10.1016/j.str.2008.07.009|imex:IM-9487	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15735288|imex:IM-9487-2|dip:DIP-88144E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0001505"(regulation of neurotransmitter levels)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001331(Guanine-nucleotide dissociation stimulator, CDC24, conserved site)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015212(Regulator of G protein signalling-like fold)|interpro:IPR016137(Regulator of G protein signalling superfamily)|interpro:IPR032919|interpro:IPR035899|interpro:IPR036034|interpro:IPR036305|interpro:IPR037803|interpro:IPR037889|interpro:IPR041020|rcsb pdb:3CX6|rcsb pdb:3CX7|rcsb pdb:3CX8|reactome:R-RNO-193648|reactome:R-RNO-416572|reactome:R-RNO-8980692|reactome:R-RNO-9013026|reactome:R-RNO-9013106|reactome:R-RNO-9013148|reactome:R-RNO-9013149|rgd:619705|refseq:NP_076472.1|dip:DIP-46242N|reactome:R-RNO-416482	refseq:NP_034433.3|dip:DIP-46241N|ensembl:ENSMUSG00000020611(gene)|ensembl:ENSMUST00000020930(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001569"(branching involved in blood vessel morphogenesis)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005834"(heterotrimeric G-protein complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0007189"(adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0030154"(cell differentiation)|go:"GO:0030168"(platelet activation)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031526"(brush border membrane)|go:"GO:0031584"(activation of phospholipase D activity)|go:"GO:0031683"(G-protein beta/gamma-subunit complex binding)|go:"GO:0031752"(D5 dopamine receptor binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042470"(melanosome)|go:"GO:0046872"(metal ion binding)|go:"GO:1904706"(negative regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1904753"(negative regulation of vascular associated smooth muscle cell migration)|interpro:IPR000469(G-protein alpha subunit, group 12)|interpro:IPR001019("Guanine nucleotide binding protein (G-protein), alpha subunit")|interpro:IPR011025(G protein alpha subunit, helical insertion)|interpro:IPR027417|mint:P27601|rcsb pdb:1SHZ|rcsb pdb:1ZCB|rcsb pdb:3AB3|rcsb pdb:3CX6|rcsb pdb:3CX7|rcsb pdb:3CX8|reactome:R-MMU-193648|reactome:R-MMU-416482|reactome:R-MMU-428930|reactome:R-MMU-456926|reactome:R-MMU-9013148|reactome:R-MMU-9013149	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/06	2017/08/10	rogid:YopqNCbuKyqNJowlb592y7ukq9Q10116	rogid:lG592gVBa3xiDv+BVn5SF8Rj/pA10090	rigid:kBYpr15TKMuHjS1+i5eTRSM0Mlo	false	binding-associated region:307-508	binding-associated region:41-377	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)