#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q8KZP4 uniprotkb:Q8KZP3 intact:EBI-15733754|ensemblbacteria:BAW02119|ensemblbacteria:VCU53970|uniprotkb:F6DHX3 intact:EBI-15733737|ensemblbacteria:VCU54425 psi-mi:q8kzp4_theth(display_long)|uniprotkb:TthHB5018_01280(orf name)|uniprotkb:secE(gene name)|psi-mi:secE(display_short)|uniprotkb:TTMY_1743(orf name)|uniprotkb:TTHN1_01760(orf name)|uniprotkb:TthAA229_01400(orf name) psi-mi:q8kzp3_theth(display_long)|uniprotkb:secY(gene name)|psi-mi:secY(display_short)|uniprotkb:TTHN1_02242(orf name) psi-mi:"MI:0071"(molecular sieving) Tsukazaki et al. (2008) pubmed:18923527|doi:10.1038/nature07421|imex:IM-17962 taxid:274(theth)|taxid:274(Thermus thermophilus) taxid:274(theth)|taxid:274(Thermus thermophilus) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15733774|imex:IM-17962-1|dip:DIP-189516E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_008630510.1|ensemblbacteria:BAW02119(transcript)|ensemblbacteria:TTHN1_01760(gene)|ensemblbacteria:TTMY_1743(gene)|ensemblbacteria:VCU53970(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0009306"(protein secretion)|go:"GO:0015450"(protein-transporting ATPase activity)|go:"GO:0006605"(protein targeting)|go:"GO:0016021"(integral component of membrane)|go:"GO:0043952"(protein transport by the Sec complex)|go:"GO:0065002"(intracellular protein transmembrane transport)|interpro:IPR001901(Protein secE/sec61-gamma protein)|interpro:IPR005807(SecE subunit of protein translocation complex)|interpro:IPR038379|dip:DIP-59814N|refseq:YP_143515.1 ensemblbacteria:TTHN1_02242(gene)|ensemblbacteria:VCU54425(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0006605"(protein targeting)|go:"GO:0016021"(integral component of membrane)|go:"GO:0043952"(protein transport by the Sec complex)|go:"GO:0065002"(intracellular protein transmembrane transport)|interpro:IPR002208(SecY protein)|interpro:IPR023201|interpro:IPR026593|interpro:IPR030659|refseq:WP_011228842.1|dip:DIP-59813N|refseq:YP_144938.1 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/06 2017/08/10 rogid:mYo0WprDOg1NMbVSXwZEEEfcj3g274 rogid:bZR0MhuyHq4SQlGDRet7QqvbJec274 rigid:8YfS0gwFwn+arjecVZY1CPtjMzA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8KZP4 uniprotkb:Q8KZP3 intact:EBI-15733754|ensemblbacteria:BAW02119|ensemblbacteria:VCU53970|uniprotkb:F6DHX3 intact:EBI-15733737|ensemblbacteria:VCU54425 psi-mi:q8kzp4_theth(display_long)|uniprotkb:TthHB5018_01280(orf name)|uniprotkb:secE(gene name)|psi-mi:secE(display_short)|uniprotkb:TTMY_1743(orf name)|uniprotkb:TTHN1_01760(orf name)|uniprotkb:TthAA229_01400(orf name) psi-mi:q8kzp3_theth(display_long)|uniprotkb:secY(gene name)|psi-mi:secY(display_short)|uniprotkb:TTHN1_02242(orf name) psi-mi:"MI:0114"(x-ray crystallography) Tsukazaki et al. (2008) pubmed:18923527|doi:10.1038/nature07421|imex:IM-17962 taxid:274(theth)|taxid:274(Thermus thermophilus) taxid:274(theth)|taxid:274(Thermus thermophilus) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15733793|imex:IM-17962-2|dip:DIP-189516E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_008630510.1|ensemblbacteria:BAW02119(transcript)|ensemblbacteria:TTHN1_01760(gene)|ensemblbacteria:TTMY_1743(gene)|ensemblbacteria:VCU53970(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0009306"(protein secretion)|go:"GO:0015450"(protein-transporting ATPase activity)|go:"GO:0006605"(protein targeting)|go:"GO:0016021"(integral component of membrane)|go:"GO:0043952"(protein transport by the Sec complex)|go:"GO:0065002"(intracellular protein transmembrane transport)|interpro:IPR001901(Protein secE/sec61-gamma protein)|interpro:IPR005807(SecE subunit of protein translocation complex)|interpro:IPR038379|dip:DIP-59814N|refseq:YP_143515.1 ensemblbacteria:TTHN1_02242(gene)|ensemblbacteria:VCU54425(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0006605"(protein targeting)|go:"GO:0016021"(integral component of membrane)|go:"GO:0043952"(protein transport by the Sec complex)|go:"GO:0065002"(intracellular protein transmembrane transport)|interpro:IPR002208(SecY protein)|interpro:IPR023201|interpro:IPR026593|interpro:IPR030659|refseq:WP_011228842.1|dip:DIP-59813N|refseq:YP_144938.1 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/06 2017/08/10 rogid:mYo0WprDOg1NMbVSXwZEEEfcj3g274 rogid:bZR0MhuyHq4SQlGDRet7QqvbJec274 rigid:8YfS0gwFwn+arjecVZY1CPtjMzA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q5SIW3 uniprotkb:Q8KZP3 intact:EBI-15733810|ensemblbacteria:BAD71074 intact:EBI-15733737|ensemblbacteria:VCU54425 psi-mi:seca_thet8(display_long)|uniprotkb:secA(gene name)|psi-mi:secA(display_short)|uniprotkb:TTHA1251(locus name) psi-mi:q8kzp3_theth(display_long)|uniprotkb:secY(gene name)|psi-mi:secY(display_short)|uniprotkb:TTHN1_02242(orf name) psi-mi:"MI:0030"(cross-linking study) Tsukazaki et al. (2008) pubmed:18923527|doi:10.1038/nature07421|imex:IM-17962 taxid:300852(thet8)|taxid:300852("Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579)") taxid:274(theth)|taxid:274(Thermus thermophilus) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15733832|imex:IM-17962-3|dip:DIP-189517E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:BAD71074(gene)|ensemblbacteria:BAD71074(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006605"(protein targeting)|go:"GO:0008564"(protein-exporting ATPase activity)|go:"GO:0017038"(protein import)|go:"GO:0065002"(intracellular protein transmembrane transport)|interpro:IPR000185(SecA protein)|interpro:IPR011115(SecA DEAD-like)|interpro:IPR011116(SecA Wing and Scaffold)|interpro:IPR011130(SecA preprotein cross-linking region)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014018(SecA motor DEAD)|interpro:IPR020937|interpro:IPR027417|interpro:IPR036266|interpro:IPR036670|interpro:IPR044722|rcsb pdb:2IPC|dip:DIP-59815N|refseq:WP_011228548.1|refseq:YP_144517.1 ensemblbacteria:TTHN1_02242(gene)|ensemblbacteria:VCU54425(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0006605"(protein targeting)|go:"GO:0016021"(integral component of membrane)|go:"GO:0043952"(protein transport by the Sec complex)|go:"GO:0065002"(intracellular protein transmembrane transport)|interpro:IPR002208(SecY protein)|interpro:IPR023201|interpro:IPR026593|interpro:IPR030659|refseq:WP_011228842.1|dip:DIP-59813N|refseq:YP_144938.1 psi-mi:"MI:0465"(dip) crc64:9A22888B52698CCA - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/06 2017/08/10 rogid:IpwJiMry1AoV4UIPpks9qWrRjrU300852 rogid:bZR0MhuyHq4SQlGDRet7QqvbJec274 rigid:px+rVChoTCu8gBP1OApfD9AKmRA false mutation:202-202|mutation:775-775 mutation:259-259|mutation:352-352 - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)