#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q24368 uniprotkb:P35875 intact:EBI-367628|uniprotkb:A4UZF0|uniprotkb:Q0E9A4|uniprotkb:Q8SX14|uniprotkb:Q9V6E8|uniprotkb:B5X0J3|ensemblmetazoa:FBpp0086954|ensemblmetazoa:FBpp0086955|ensemblmetazoa:FBpp0086956 intact:EBI-266172|uniprotkb:A8Y590|uniprotkb:Q7PLT6|uniprotkb:Q8MSB5|uniprotkb:Q8MU87|uniprotkb:Q9W5Q5|uniprotkb:Q9W5S1|ensemblmetazoa:FBpp0112608 psi-mi:iswi_drome(display_long)|uniprotkb:Iswi(gene name)|psi-mi:Iswi(display_short)|uniprotkb:CG8625(orf name)|uniprotkb:Protein imitation swi(gene name synonym)|uniprotkb:Nucleosome-remodeling factor 140 kDa subunit(gene name synonym)|uniprotkb:CHRAC 140 kDa subunit(gene name synonym) psi-mi:parp_drome(display_long)|uniprotkb:Parp(gene name)|psi-mi:Parp(display_short)|uniprotkb:Poly[ADP-ribose] synthase(gene name synonym)|uniprotkb:"NAD(+) ADP-ribosyltransferase"(gene name synonym)|uniprotkb:Protein ADP-ribosyltransferase Parp(gene name synonym)|uniprotkb:CG40411(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sala et al. (2008) pubmed:18922045|doi:10.1371/journal.pbio.0060252|imex:IM-9492 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15733136|imex:IM-9492-2|dip:DIP-88151E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_523719.1|refseq:NP_725203.1|refseq:NP_725204.1|flybase:FBgn0011604|go:"GO:0031213"(RSF complex)|interpro:IPR044754|mint:Q24368|rcsb pdb:1OFC|ensemblmetazoa:FBgn0011604(gene)|go:"GO:0031010"(ISWI-type complex)|ensemblmetazoa:FBtr0087841(transcript)|ensemblmetazoa:FBtr0087842(transcript)|ensemblmetazoa:FBtr0087843(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0003677"(DNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005700"(polytene chromosome)|go:"GO:0006325"(chromatin organization)|go:"GO:0006333"(chromatin assembly or disassembly)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008623"(CHRAC)|go:"GO:0016584"(nucleosome positioning)|go:"GO:0016589"(NURF complex)|go:"GO:0016590"(ACF complex)|go:"GO:0035041"(sperm DNA decondensation)|go:"GO:0035063"(nuclear speck organization)|go:"GO:0035076"(ecdysone receptor-mediated signaling pathway)|go:"GO:0031491"(nucleosome binding)|go:"GO:0016787"(hydrolase activity)|go:"GO:0035092"(sperm DNA condensation)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042766"(nucleosome mobilization)|go:"GO:0043044"|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0070615"|interpro:IPR000330(SNF2-related)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR009057(Homeodomain-like)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR015194(Nucleosome remodelling ATPase ISWI, HAND)|interpro:IPR015195(SLIDE)|interpro:IPR017884|interpro:IPR020838|interpro:IPR027417|interpro:IPR036306|interpro:IPR038718|dip:DIP-24067N refseq:NP_001104452.1|flybase:FBgn0010247|dip:DIP-23413N|ensemblmetazoa:FBgn0010247(gene)|ensemblmetazoa:FBtr0113885(transcript)|go:"GO:0000791"(euchromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003950"(NAD+ ADP-ribosyltransferase activity)|go:"GO:0005694"(chromosome)|go:"GO:0005700"(polytene chromosome)|go:"GO:0005703"(polytene chromosome puff)|go:"GO:0005730"(nucleolus)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006325"(chromatin organization)|go:"GO:0006471"(protein ADP-ribosylation)|go:"GO:0006963"(positive regulation of antibacterial peptide biosynthetic process)|go:"GO:0007000"(nucleolus organization)|go:"GO:0008069"(dorsal/ventral axis specification, ovarian follicular epithelium)|go:"GO:0008270"(zinc ion binding)|go:"GO:0015030"(Cajal body)|go:"GO:0030576"(Cajal body organization)|go:"GO:0035079"(polytene chromosome puffing)|go:"GO:0035080"(heat shock-mediated polytene chromosome puffing)|go:"GO:0035363"(histone locus body)|go:"GO:0042393"(histone binding)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0045087"(innate immune response)|go:"GO:0051287"(NAD binding)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0061059"(positive regulation of peptidoglycan recognition protein signaling pathway)|go:"GO:0070212"(protein poly-ADP-ribosylation)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1990404"(protein ADP-ribosylase activity)|interpro:IPR001357(BRCT)|interpro:IPR001510(Zinc finger, PARP-type)|interpro:IPR004102("Poly(ADP-ribose) polymerase, regulatory region")|interpro:IPR008288(NAD+ ADP-ribosyltransferase)|interpro:IPR008893(WGR)|interpro:IPR012317("Poly(ADP-ribose) polymerase, catalytic region")|interpro:IPR012982(PADR1)|interpro:IPR036420|interpro:IPR036616|interpro:IPR036930|interpro:IPR036957|interpro:IPR038650|reactome:R-DME-110362|reactome:R-DME-2173795|reactome:R-DME-3108214|reactome:R-DME-5685939|reactome:R-DME-5696394|reactome:R-DME-5696395|reactome:R-DME-5696400 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2017/08/06 2017/08/10 rogid:Y+DR8T/CS52ezjthM6C5qhkyPiw7227 rogid:SAV/yTZOCz9I+TRMEaZEyYYQ8Kw7227 rigid:FHpHdsircQwy3/gCTjwboeQi0Ws false ha tag:n-n - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P09874 uniprotkb:Q24368 intact:EBI-355676|uniprotkb:Q8IUZ9|uniprotkb:B1ANJ4|ensembl:ENSP00000355759 intact:EBI-367628|uniprotkb:A4UZF0|uniprotkb:Q0E9A4|uniprotkb:Q8SX14|uniprotkb:Q9V6E8|uniprotkb:B5X0J3|ensemblmetazoa:FBpp0086954|ensemblmetazoa:FBpp0086955|ensemblmetazoa:FBpp0086956 psi-mi:parp1_human(display_long)|uniprotkb:PARP1(gene name)|psi-mi:PARP1(display_short)|uniprotkb:ADPRT(gene name synonym)|uniprotkb:PPOL(gene name synonym)|uniprotkb:"NAD(+) ADP-ribosyltransferase 1"(gene name synonym)|uniprotkb:Poly[ADP-ribose] synthase 1(gene name synonym)|uniprotkb:ADP-ribosyltransferase diphtheria toxin-like 1(gene name synonym)|uniprotkb:DNA ADP-ribosyltransferase PARP1(gene name synonym)|uniprotkb:Protein poly-ADP-ribosyltransferase PARP1(gene name synonym) psi-mi:iswi_drome(display_long)|uniprotkb:Iswi(gene name)|psi-mi:Iswi(display_short)|uniprotkb:CG8625(orf name)|uniprotkb:Protein imitation swi(gene name synonym)|uniprotkb:Nucleosome-remodeling factor 140 kDa subunit(gene name synonym)|uniprotkb:CHRAC 140 kDa subunit(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sala et al. (2008) pubmed:18922045|doi:10.1371/journal.pbio.0060252|imex:IM-9492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15733174|imex:IM-9492-1|dip:DIP-88152E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001609.2|rcsb pdb:7AAC|rcsb pdb:7AAD|rcsb pdb:6NRJ|rcsb pdb:6NTU|rcsb pdb:7CMW|rcsb pdb:6VKK|rcsb pdb:7KK2|rcsb pdb:7KK3|rcsb pdb:7KK4|rcsb pdb:7KK5|rcsb pdb:7KK6|reactome:R-HSA-110362|reactome:R-HSA-192814|reactome:R-HSA-2173795|reactome:R-HSA-3108214|reactome:R-HSA-5685939|reactome:R-HSA-5696394|reactome:R-HSA-5696395|reactome:R-HSA-5696400|rcsb pdb:6VKO|rcsb pdb:6VKQ|rcsb pdb:6XVW|rcsb pdb:7AAA|rcsb pdb:7AAB|ensembl:ENSG00000143799(gene)|ensembl:ENST00000366794(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003950"(NAD+ ADP-ribosyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|go:"GO:0006281"(DNA repair)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006471"(protein ADP-ribosylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010332"(response to gamma radiation)|go:"GO:0010613"(positive regulation of cardiac muscle hypertrophy)|go:"GO:0010990"(regulation of SMAD protein complex assembly)|go:"GO:0016020"(membrane)|go:"GO:0016540"(protein autoprocessing)|go:"GO:0016604"(nuclear body)|go:"GO:0018312"(peptidyl-serine ADP-ribosylation)|go:"GO:0018424"(peptidyl-glutamic acid poly-ADP-ribosylation)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0023019"(signal transduction involved in regulation of gene expression)|go:"GO:0030225"(macrophage differentiation)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030592"(DNA ADP-ribosylation)|go:"GO:0032042"(mitochondrial DNA metabolic process)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0032991"(protein-containing complex)|go:"GO:0008270"(zinc ion binding)|go:"GO:0035861"(site of double-strand break)|go:"GO:0036211"(protein modification process)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0042802"(identical protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043504"(mitochondrial DNA repair)|go:"GO:0044030"(regulation of DNA methylation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0051287"(NAD binding)|go:"GO:0051901"(positive regulation of mitochondrial depolarization)|go:"GO:0060391"(positive regulation of SMAD protein signal transduction)|go:"GO:0070212"(protein poly-ADP-ribosylation)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033148"(positive regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0070213"(protein auto-ADP-ribosylation)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0070412"(R-SMAD binding)|go:"GO:0034644"(cellular response to UV)|go:"GO:0071294"(cellular response to zinc ion)|go:"GO:0090734"(site of DNA damage)|go:"GO:0140294"(NAD DNA ADP-ribosyltransferase activity)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1903376"(regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway)|go:"GO:1903518"(positive regulation of single strand break repair)|go:"GO:1904044"(response to aldosterone)|go:"GO:1904357"(negative regulation of telomere maintenance via telomere lengthening)|go:"GO:1904646"(cellular response to amyloid-beta)|go:"GO:1904762"(positive regulation of myofibroblast differentiation)|go:"GO:1905168"(positive regulation of double-strand break repair via homologous recombination)|go:"GO:1990404"(protein ADP-ribosylase activity)|go:"GO:1990966"(ATP generation from poly-ADP-D-ribose)|go:"GO:2000679"(positive regulation of transcription regulatory region DNA binding)|go:"GO:2001170"(negative regulation of ATP biosynthetic process)|interpro:IPR001357(BRCT)|interpro:IPR001510(Zinc finger, PARP-type)|interpro:IPR004102("Poly(ADP-ribose) polymerase, regulatory region")|interpro:IPR008288(NAD+ ADP-ribosyltransferase)|interpro:IPR008893(WGR)|interpro:IPR012317("Poly(ADP-ribose) polymerase, catalytic region")|interpro:IPR012982(PADR1)|interpro:IPR036420|interpro:IPR036616|interpro:IPR036930|interpro:IPR036957|interpro:IPR038650|mint:P09874|rcsb pdb:1UK0|rcsb pdb:1UK1|rcsb pdb:1WOK|rcsb pdb:2COK|rcsb pdb:2CR9|rcsb pdb:2CS2|rcsb pdb:2DMJ|rcsb pdb:2JVN|go:"GO:1903827"|rcsb pdb:2L30|rcsb pdb:2N8A|rcsb pdb:2RCW|rcsb pdb:2RD6|rcsb pdb:2RIQ|rcsb pdb:2L31|rcsb pdb:3GJW|rcsb pdb:3GN7|rcsb pdb:3L3L|rcsb pdb:3L3M|rcsb pdb:3OD8|rcsb pdb:3ODA|rcsb pdb:3ODC|rcsb pdb:3ODE|rcsb pdb:4AV1|rcsb pdb:4DQY|rcsb pdb:4GV7|rcsb pdb:4HHY|rcsb pdb:4HHZ|rcsb pdb:4L6S|rcsb pdb:4OPX|rcsb pdb:4OQA|rcsb pdb:4OQB|rcsb pdb:4PJT|rcsb pdb:4R5W|rcsb pdb:4R6E|rcsb pdb:4RV6|rcsb pdb:4UND|rcsb pdb:4UXB|rcsb pdb:4XHU|rcsb pdb:5A00|rcsb pdb:5DS3|rcsb pdb:5HA9|rcsb pdb:5KPN|rcsb pdb:5KPO|rcsb pdb:5KPP|rcsb pdb:5KPQ|rcsb pdb:5WRQ|rcsb pdb:5WRY|rcsb pdb:5WRZ|rcsb pdb:5WS0|rcsb pdb:5WS1|rcsb pdb:5WTC|rcsb pdb:4ZZZ|rcsb pdb:5XSR|rcsb pdb:5XST|rcsb pdb:5XSU|rcsb pdb:6BHV|rcsb pdb:6GHK|rcsb pdb:6M3I|rcsb pdb:6NRF|rcsb pdb:6NRG|rcsb pdb:6NRH|rcsb pdb:6NRI|dip:DIP-38N refseq:NP_523719.1|refseq:NP_725203.1|refseq:NP_725204.1|flybase:FBgn0011604|go:"GO:0031213"(RSF complex)|interpro:IPR044754|mint:Q24368|rcsb pdb:1OFC|ensemblmetazoa:FBgn0011604(gene)|go:"GO:0031010"(ISWI-type complex)|ensemblmetazoa:FBtr0087841(transcript)|ensemblmetazoa:FBtr0087842(transcript)|ensemblmetazoa:FBtr0087843(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0003677"(DNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005700"(polytene chromosome)|go:"GO:0006325"(chromatin organization)|go:"GO:0006333"(chromatin assembly or disassembly)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008623"(CHRAC)|go:"GO:0016584"(nucleosome positioning)|go:"GO:0016589"(NURF complex)|go:"GO:0016590"(ACF complex)|go:"GO:0035041"(sperm DNA decondensation)|go:"GO:0035063"(nuclear speck organization)|go:"GO:0035076"(ecdysone receptor-mediated signaling pathway)|go:"GO:0031491"(nucleosome binding)|go:"GO:0016787"(hydrolase activity)|go:"GO:0035092"(sperm DNA condensation)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042766"(nucleosome mobilization)|go:"GO:0043044"|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0070615"|interpro:IPR000330(SNF2-related)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR009057(Homeodomain-like)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR015194(Nucleosome remodelling ATPase ISWI, HAND)|interpro:IPR015195(SLIDE)|interpro:IPR017884|interpro:IPR020838|interpro:IPR027417|interpro:IPR036306|interpro:IPR038718|dip:DIP-24067N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/06 2017/08/10 rogid:VC+4HLilGJuoiTbk4/fSeRw9+iY9606 rogid:Y+DR8T/CS52ezjthM6C5qhkyPiw7227 rigid:R78G4/Za0QTEyt3JN95adZXgKS4 false - flag tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q24368 uniprotkb:P35875 intact:EBI-367628|uniprotkb:A4UZF0|uniprotkb:Q0E9A4|uniprotkb:Q8SX14|uniprotkb:Q9V6E8|uniprotkb:B5X0J3|ensemblmetazoa:FBpp0086954|ensemblmetazoa:FBpp0086955|ensemblmetazoa:FBpp0086956 intact:EBI-266172|uniprotkb:A8Y590|uniprotkb:Q7PLT6|uniprotkb:Q8MSB5|uniprotkb:Q8MU87|uniprotkb:Q9W5Q5|uniprotkb:Q9W5S1|ensemblmetazoa:FBpp0112608 psi-mi:iswi_drome(display_long)|uniprotkb:Iswi(gene name)|psi-mi:Iswi(display_short)|uniprotkb:CG8625(orf name)|uniprotkb:Protein imitation swi(gene name synonym)|uniprotkb:Nucleosome-remodeling factor 140 kDa subunit(gene name synonym)|uniprotkb:CHRAC 140 kDa subunit(gene name synonym) psi-mi:parp_drome(display_long)|uniprotkb:Parp(gene name)|psi-mi:Parp(display_short)|uniprotkb:Poly[ADP-ribose] synthase(gene name synonym)|uniprotkb:"NAD(+) ADP-ribosyltransferase"(gene name synonym)|uniprotkb:Protein ADP-ribosyltransferase Parp(gene name synonym)|uniprotkb:CG40411(orf name) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Sala et al. (2008) pubmed:18922045|doi:10.1371/journal.pbio.0060252|imex:IM-9492 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15733193|imex:IM-9492-4|dip:DIP-88151E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_523719.1|refseq:NP_725203.1|refseq:NP_725204.1|flybase:FBgn0011604|go:"GO:0031213"(RSF complex)|interpro:IPR044754|mint:Q24368|rcsb pdb:1OFC|ensemblmetazoa:FBgn0011604(gene)|go:"GO:0031010"(ISWI-type complex)|ensemblmetazoa:FBtr0087841(transcript)|ensemblmetazoa:FBtr0087842(transcript)|ensemblmetazoa:FBtr0087843(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0003677"(DNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005700"(polytene chromosome)|go:"GO:0006325"(chromatin organization)|go:"GO:0006333"(chromatin assembly or disassembly)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008623"(CHRAC)|go:"GO:0016584"(nucleosome positioning)|go:"GO:0016589"(NURF complex)|go:"GO:0016590"(ACF complex)|go:"GO:0035041"(sperm DNA decondensation)|go:"GO:0035063"(nuclear speck organization)|go:"GO:0035076"(ecdysone receptor-mediated signaling pathway)|go:"GO:0031491"(nucleosome binding)|go:"GO:0016787"(hydrolase activity)|go:"GO:0035092"(sperm DNA condensation)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042766"(nucleosome mobilization)|go:"GO:0043044"|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0070615"|interpro:IPR000330(SNF2-related)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR009057(Homeodomain-like)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR015194(Nucleosome remodelling ATPase ISWI, HAND)|interpro:IPR015195(SLIDE)|interpro:IPR017884|interpro:IPR020838|interpro:IPR027417|interpro:IPR036306|interpro:IPR038718|dip:DIP-24067N refseq:NP_001104452.1|flybase:FBgn0010247|dip:DIP-23413N|ensemblmetazoa:FBgn0010247(gene)|ensemblmetazoa:FBtr0113885(transcript)|go:"GO:0000791"(euchromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003950"(NAD+ ADP-ribosyltransferase activity)|go:"GO:0005694"(chromosome)|go:"GO:0005700"(polytene chromosome)|go:"GO:0005703"(polytene chromosome puff)|go:"GO:0005730"(nucleolus)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006325"(chromatin organization)|go:"GO:0006471"(protein ADP-ribosylation)|go:"GO:0006963"(positive regulation of antibacterial peptide biosynthetic process)|go:"GO:0007000"(nucleolus organization)|go:"GO:0008069"(dorsal/ventral axis specification, ovarian follicular epithelium)|go:"GO:0008270"(zinc ion binding)|go:"GO:0015030"(Cajal body)|go:"GO:0030576"(Cajal body organization)|go:"GO:0035079"(polytene chromosome puffing)|go:"GO:0035080"(heat shock-mediated polytene chromosome puffing)|go:"GO:0035363"(histone locus body)|go:"GO:0042393"(histone binding)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0045087"(innate immune response)|go:"GO:0051287"(NAD binding)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0061059"(positive regulation of peptidoglycan recognition protein signaling pathway)|go:"GO:0070212"(protein poly-ADP-ribosylation)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1990404"(protein ADP-ribosylase activity)|interpro:IPR001357(BRCT)|interpro:IPR001510(Zinc finger, PARP-type)|interpro:IPR004102("Poly(ADP-ribose) polymerase, regulatory region")|interpro:IPR008288(NAD+ ADP-ribosyltransferase)|interpro:IPR008893(WGR)|interpro:IPR012317("Poly(ADP-ribose) polymerase, catalytic region")|interpro:IPR012982(PADR1)|interpro:IPR036420|interpro:IPR036616|interpro:IPR036930|interpro:IPR036957|interpro:IPR038650|reactome:R-DME-110362|reactome:R-DME-2173795|reactome:R-DME-3108214|reactome:R-DME-5685939|reactome:R-DME-5696394|reactome:R-DME-5696395|reactome:R-DME-5696400 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2017/08/06 2017/08/10 rogid:Y+DR8T/CS52ezjthM6C5qhkyPiw7227 rogid:SAV/yTZOCz9I+TRMEaZEyYYQ8Kw7227 rigid:FHpHdsircQwy3/gCTjwboeQi0Ws false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q24368 uniprotkb:P35875 intact:EBI-367628|uniprotkb:A4UZF0|uniprotkb:Q0E9A4|uniprotkb:Q8SX14|uniprotkb:Q9V6E8|uniprotkb:B5X0J3|ensemblmetazoa:FBpp0086954|ensemblmetazoa:FBpp0086955|ensemblmetazoa:FBpp0086956 intact:EBI-266172|uniprotkb:A8Y590|uniprotkb:Q7PLT6|uniprotkb:Q8MSB5|uniprotkb:Q8MU87|uniprotkb:Q9W5Q5|uniprotkb:Q9W5S1|ensemblmetazoa:FBpp0112608 psi-mi:iswi_drome(display_long)|uniprotkb:Iswi(gene name)|psi-mi:Iswi(display_short)|uniprotkb:CG8625(orf name)|uniprotkb:Protein imitation swi(gene name synonym)|uniprotkb:Nucleosome-remodeling factor 140 kDa subunit(gene name synonym)|uniprotkb:CHRAC 140 kDa subunit(gene name synonym) psi-mi:parp_drome(display_long)|uniprotkb:Parp(gene name)|psi-mi:Parp(display_short)|uniprotkb:Poly[ADP-ribose] synthase(gene name synonym)|uniprotkb:"NAD(+) ADP-ribosyltransferase"(gene name synonym)|uniprotkb:Protein ADP-ribosyltransferase Parp(gene name synonym)|uniprotkb:CG40411(orf name) psi-mi:"MI:0676"(tandem affinity purification) Sala et al. (2008) pubmed:18922045|doi:10.1371/journal.pbio.0060252|imex:IM-9492 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15733155|imex:IM-9492-3|dip:DIP-88151E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_523719.1|refseq:NP_725203.1|refseq:NP_725204.1|flybase:FBgn0011604|go:"GO:0031213"(RSF complex)|interpro:IPR044754|mint:Q24368|rcsb pdb:1OFC|ensemblmetazoa:FBgn0011604(gene)|go:"GO:0031010"(ISWI-type complex)|ensemblmetazoa:FBtr0087841(transcript)|ensemblmetazoa:FBtr0087842(transcript)|ensemblmetazoa:FBtr0087843(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0003677"(DNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005700"(polytene chromosome)|go:"GO:0006325"(chromatin organization)|go:"GO:0006333"(chromatin assembly or disassembly)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008623"(CHRAC)|go:"GO:0016584"(nucleosome positioning)|go:"GO:0016589"(NURF complex)|go:"GO:0016590"(ACF complex)|go:"GO:0035041"(sperm DNA decondensation)|go:"GO:0035063"(nuclear speck organization)|go:"GO:0035076"(ecdysone receptor-mediated signaling pathway)|go:"GO:0031491"(nucleosome binding)|go:"GO:0016787"(hydrolase activity)|go:"GO:0035092"(sperm DNA condensation)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042766"(nucleosome mobilization)|go:"GO:0043044"|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0070615"|interpro:IPR000330(SNF2-related)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR009057(Homeodomain-like)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR015194(Nucleosome remodelling ATPase ISWI, HAND)|interpro:IPR015195(SLIDE)|interpro:IPR017884|interpro:IPR020838|interpro:IPR027417|interpro:IPR036306|interpro:IPR038718|dip:DIP-24067N refseq:NP_001104452.1|flybase:FBgn0010247|dip:DIP-23413N|ensemblmetazoa:FBgn0010247(gene)|ensemblmetazoa:FBtr0113885(transcript)|go:"GO:0000791"(euchromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003950"(NAD+ ADP-ribosyltransferase activity)|go:"GO:0005694"(chromosome)|go:"GO:0005700"(polytene chromosome)|go:"GO:0005703"(polytene chromosome puff)|go:"GO:0005730"(nucleolus)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006325"(chromatin organization)|go:"GO:0006471"(protein ADP-ribosylation)|go:"GO:0006963"(positive regulation of antibacterial peptide biosynthetic process)|go:"GO:0007000"(nucleolus organization)|go:"GO:0008069"(dorsal/ventral axis specification, ovarian follicular epithelium)|go:"GO:0008270"(zinc ion binding)|go:"GO:0015030"(Cajal body)|go:"GO:0030576"(Cajal body organization)|go:"GO:0035079"(polytene chromosome puffing)|go:"GO:0035080"(heat shock-mediated polytene chromosome puffing)|go:"GO:0035363"(histone locus body)|go:"GO:0042393"(histone binding)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0045087"(innate immune response)|go:"GO:0051287"(NAD binding)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0061059"(positive regulation of peptidoglycan recognition protein signaling pathway)|go:"GO:0070212"(protein poly-ADP-ribosylation)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1990404"(protein ADP-ribosylase activity)|interpro:IPR001357(BRCT)|interpro:IPR001510(Zinc finger, PARP-type)|interpro:IPR004102("Poly(ADP-ribose) polymerase, regulatory region")|interpro:IPR008288(NAD+ ADP-ribosyltransferase)|interpro:IPR008893(WGR)|interpro:IPR012317("Poly(ADP-ribose) polymerase, catalytic region")|interpro:IPR012982(PADR1)|interpro:IPR036420|interpro:IPR036616|interpro:IPR036930|interpro:IPR036957|interpro:IPR038650|reactome:R-DME-110362|reactome:R-DME-2173795|reactome:R-DME-3108214|reactome:R-DME-5685939|reactome:R-DME-5696394|reactome:R-DME-5696395|reactome:R-DME-5696400 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2017/08/06 2017/08/10 rogid:Y+DR8T/CS52ezjthM6C5qhkyPiw7227 rogid:SAV/yTZOCz9I+TRMEaZEyYYQ8Kw7227 rigid:FHpHdsircQwy3/gCTjwboeQi0Ws false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q24368 uniprotkb:P35875 intact:EBI-367628|uniprotkb:A4UZF0|uniprotkb:Q0E9A4|uniprotkb:Q8SX14|uniprotkb:Q9V6E8|uniprotkb:B5X0J3|ensemblmetazoa:FBpp0086954|ensemblmetazoa:FBpp0086955|ensemblmetazoa:FBpp0086956 intact:EBI-266172|uniprotkb:A8Y590|uniprotkb:Q7PLT6|uniprotkb:Q8MSB5|uniprotkb:Q8MU87|uniprotkb:Q9W5Q5|uniprotkb:Q9W5S1|ensemblmetazoa:FBpp0112608 psi-mi:iswi_drome(display_long)|uniprotkb:Iswi(gene name)|psi-mi:Iswi(display_short)|uniprotkb:CG8625(orf name)|uniprotkb:Protein imitation swi(gene name synonym)|uniprotkb:Nucleosome-remodeling factor 140 kDa subunit(gene name synonym)|uniprotkb:CHRAC 140 kDa subunit(gene name synonym) psi-mi:parp_drome(display_long)|uniprotkb:Parp(gene name)|psi-mi:Parp(display_short)|uniprotkb:Poly[ADP-ribose] synthase(gene name synonym)|uniprotkb:"NAD(+) ADP-ribosyltransferase"(gene name synonym)|uniprotkb:Protein ADP-ribosyltransferase Parp(gene name synonym)|uniprotkb:CG40411(orf name) psi-mi:"MI:0096"(pull down) Sala et al. (2008) pubmed:18922045|doi:10.1371/journal.pbio.0060252|imex:IM-9492 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15733210|imex:IM-9492-5|dip:DIP-88151E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_523719.1|refseq:NP_725203.1|refseq:NP_725204.1|flybase:FBgn0011604|go:"GO:0031213"(RSF complex)|interpro:IPR044754|mint:Q24368|rcsb pdb:1OFC|ensemblmetazoa:FBgn0011604(gene)|go:"GO:0031010"(ISWI-type complex)|ensemblmetazoa:FBtr0087841(transcript)|ensemblmetazoa:FBtr0087842(transcript)|ensemblmetazoa:FBtr0087843(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0003677"(DNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005700"(polytene chromosome)|go:"GO:0006325"(chromatin organization)|go:"GO:0006333"(chromatin assembly or disassembly)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008623"(CHRAC)|go:"GO:0016584"(nucleosome positioning)|go:"GO:0016589"(NURF complex)|go:"GO:0016590"(ACF complex)|go:"GO:0035041"(sperm DNA decondensation)|go:"GO:0035063"(nuclear speck organization)|go:"GO:0035076"(ecdysone receptor-mediated signaling pathway)|go:"GO:0031491"(nucleosome binding)|go:"GO:0016787"(hydrolase activity)|go:"GO:0035092"(sperm DNA condensation)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042766"(nucleosome mobilization)|go:"GO:0043044"|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0070615"|interpro:IPR000330(SNF2-related)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR009057(Homeodomain-like)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR015194(Nucleosome remodelling ATPase ISWI, HAND)|interpro:IPR015195(SLIDE)|interpro:IPR017884|interpro:IPR020838|interpro:IPR027417|interpro:IPR036306|interpro:IPR038718|dip:DIP-24067N refseq:NP_001104452.1|flybase:FBgn0010247|dip:DIP-23413N|ensemblmetazoa:FBgn0010247(gene)|ensemblmetazoa:FBtr0113885(transcript)|go:"GO:0000791"(euchromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003950"(NAD+ ADP-ribosyltransferase activity)|go:"GO:0005694"(chromosome)|go:"GO:0005700"(polytene chromosome)|go:"GO:0005703"(polytene chromosome puff)|go:"GO:0005730"(nucleolus)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006325"(chromatin organization)|go:"GO:0006471"(protein ADP-ribosylation)|go:"GO:0006963"(positive regulation of antibacterial peptide biosynthetic process)|go:"GO:0007000"(nucleolus organization)|go:"GO:0008069"(dorsal/ventral axis specification, ovarian follicular epithelium)|go:"GO:0008270"(zinc ion binding)|go:"GO:0015030"(Cajal body)|go:"GO:0030576"(Cajal body organization)|go:"GO:0035079"(polytene chromosome puffing)|go:"GO:0035080"(heat shock-mediated polytene chromosome puffing)|go:"GO:0035363"(histone locus body)|go:"GO:0042393"(histone binding)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0045087"(innate immune response)|go:"GO:0051287"(NAD binding)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0061059"(positive regulation of peptidoglycan recognition protein signaling pathway)|go:"GO:0070212"(protein poly-ADP-ribosylation)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1990404"(protein ADP-ribosylase activity)|interpro:IPR001357(BRCT)|interpro:IPR001510(Zinc finger, PARP-type)|interpro:IPR004102("Poly(ADP-ribose) polymerase, regulatory region")|interpro:IPR008288(NAD+ ADP-ribosyltransferase)|interpro:IPR008893(WGR)|interpro:IPR012317("Poly(ADP-ribose) polymerase, catalytic region")|interpro:IPR012982(PADR1)|interpro:IPR036420|interpro:IPR036616|interpro:IPR036930|interpro:IPR036957|interpro:IPR038650|reactome:R-DME-110362|reactome:R-DME-2173795|reactome:R-DME-3108214|reactome:R-DME-5685939|reactome:R-DME-5696394|reactome:R-DME-5696395|reactome:R-DME-5696400 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2017/08/06 2017/08/10 rogid:Y+DR8T/CS52ezjthM6C5qhkyPiw7227 rogid:SAV/yTZOCz9I+TRMEaZEyYYQ8Kw7227 rigid:FHpHdsircQwy3/gCTjwboeQi0Ws false his tag:n-n - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot)