#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q92793	uniprotkb:Q13568	intact:EBI-81215|ensembl:ENSP00000262367|uniprotkb:O00147|uniprotkb:Q16376|uniprotkb:D3DUC9|uniprotkb:Q4LE28	intact:EBI-3931258|uniprotkb:E7EQ16|uniprotkb:Q64GB1|uniprotkb:Q9BQF0|uniprotkb:Q64GB2|intact:EBI-28983960|ensembl:ENSP00000249375|ensembl:ENSP00000385352|ensembl:ENSP00000419149|uniprotkb:A4D1J8|uniprotkb:A8DUA8|uniprotkb:A8DUA9|uniprotkb:Q6RCM8|uniprotkb:E7EW54|uniprotkb:Q64GA9|uniprotkb:Q1A7B4	psi-mi:cbp_human(display_long)|uniprotkb:CREBBP(gene name)|psi-mi:CREBBP(display_short)|uniprotkb:CBP(gene name synonym)|uniprotkb:Histone lysine acetyltransferase CREBBP(gene name synonym)|uniprotkb:Protein-lysine acetyltransferase CREBBP(gene name synonym)	psi-mi:irf5_human(display_long)|uniprotkb:IRF5(gene name)|psi-mi:IRF5(display_short)	psi-mi:"MI:0028"(cosedimentation in solution)	Chen et al. (2008)	pubmed:18836453|doi:10.1038/nsmb.1496|imex:IM-9614	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15731736|imex:IM-9614-5|dip:DIP-88315E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000005339(gene)|ensembl:ENST00000262367(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0000785"(chromatin)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0001666"(response to hypoxia)|go:"GO:0002039"(p53 binding)|go:"GO:0002223"(stimulatory C-type lectin receptor signaling pathway)|go:"GO:0003682"(chromatin binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006473"(protein acetylation)|go:"GO:0007165"(signal transduction)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0016407"(acetyltransferase activity)|go:"GO:0016573"(histone acetylation)|go:"GO:0016604"(nuclear body)|go:"GO:0018076"(N-terminal peptidyl-lysine acetylation)|go:"GO:0030511"(positive regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031648"(protein destabilization)|go:"GO:0034212"(peptide N-acetyltransferase activity)|go:"GO:0034644"(cellular response to UV)|go:"GO:0042592"(homeostatic process)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0043426"(MRF binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048511"(rhythmic process)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0061733"(peptide-lysine-N-acetyltransferase activity)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:1900034"(regulation of cellular response to heat)|go:"GO:1990258"(histone glutamine methylation)|interpro:IPR000197(Zinc finger, TAZ-type)|interpro:IPR000433(Zinc finger, ZZ-type)|interpro:IPR001487(Bromodomain)|interpro:IPR003101(Coactivator CBP, KIX)|interpro:IPR009110(Nuclear receptor coactivator, interlocking)|interpro:IPR010303(Protein of unknown function DUF902, CREBbp)|rcsb pdb:1WO7|rcsb pdb:1ZOQ|rcsb pdb:2D82|rcsb pdb:2KJE|rcsb pdb:2KWF|rcsb pdb:2L84|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013178(H3K56 histone acetylation protein, RTT109)|interpro:IPR014744(Nuclear receptor coactivator, CREB-bp-like, interlocking)|interpro:IPR018359|interpro:IPR031162|interpro:IPR035898|interpro:IPR036427|interpro:IPR036529|interpro:IPR037073|interpro:IPR038547|interpro:IPR043145|mint:Q92793|rcsb pdb:1JSP|rcsb pdb:1LIQ|rcsb pdb:1RDT|rcsb pdb:1WO3|rcsb pdb:1WO4|rcsb pdb:1WO5|rcsb pdb:1WO6|rcsb pdb:2L85|rcsb pdb:2LXT|rcsb pdb:2LXS|rcsb pdb:3DWY|rcsb pdb:2N1A|rcsb pdb:3P1C|rcsb pdb:3P1D|refseq:NP_001073315.1|refseq:NP_004371.2|rcsb pdb:3P1E|rcsb pdb:3P1F|rcsb pdb:2RNY|rcsb pdb:6AY3|rcsb pdb:6AY5|rcsb pdb:6DMK|rcsb pdb:6ES5|rcsb pdb:6ES6|rcsb pdb:6ES7|rcsb pdb:6SQM|rcsb pdb:6FQO|rcsb pdb:6SXX|rcsb pdb:6YIJ|rcsb pdb:6YIK|rcsb pdb:6YIL|rcsb pdb:6YIM|rcsb pdb:6FQT|rcsb pdb:7CO1|rcsb pdb:7JFL|rcsb pdb:7JFM|reactome:R-HSA-1234158|rcsb pdb:6FQU|reactome:R-HSA-1368082|reactome:R-HSA-1368108|reactome:R-HSA-1912408|rcsb pdb:6FR0|rcsb pdb:6FRF|rcsb pdb:6M64|rcsb pdb:6QST|reactome:R-HSA-1989781|reactome:R-HSA-201722|reactome:R-HSA-210744|reactome:R-HSA-2122947|reactome:R-HSA-2151201|reactome:R-HSA-2426168|reactome:R-HSA-2644606|rcsb pdb:6SQE|rcsb pdb:6SQF|reactome:R-HSA-2894862|reactome:R-HSA-3134973|reactome:R-HSA-3214847|reactome:R-HSA-3371568|reactome:R-HSA-350054|reactome:R-HSA-381340|reactome:R-HSA-3899300|reactome:R-HSA-400206|reactome:R-HSA-400253|reactome:R-HSA-5617472|reactome:R-HSA-5621575|reactome:R-HSA-6803204|reactome:R-HSA-8866907|reactome:R-HSA-8939246|reactome:R-HSA-8941856|reactome:R-HSA-9013508|reactome:R-HSA-9013695|reactome:R-HSA-9018519|reactome:R-HSA-918233|reactome:R-HSA-933541|reactome:R-HSA-9614657|rcsb pdb:3SVH|rcsb pdb:4A9K|rcsb pdb:4N3W|rcsb pdb:4N4F|rcsb pdb:4NR4|rcsb pdb:4NR5|rcsb pdb:4NR6|rcsb pdb:4NR7|rcsb pdb:4NYV|rcsb pdb:4NYW|rcsb pdb:4NYX|rcsb pdb:4OUF|rcsb pdb:4TQN|rcsb pdb:4TS8|rcsb pdb:4WHU|rcsb pdb:4YK0|rcsb pdb:5CGP|rcsb pdb:5DBM|rcsb pdb:5EIC|rcsb pdb:5ENG|rcsb pdb:5EP7|rcsb pdb:5GH9|rcsb pdb:5H85|rcsb pdb:5I83|rcsb pdb:5I86|rcsb pdb:5I89|rcsb pdb:5I8B|rcsb pdb:5I8G|rcsb pdb:5J0D|rcsb pdb:5JEM|rcsb pdb:5KTU|rcsb pdb:5KTW|rcsb pdb:5KTX|rcsb pdb:5LPJ|rcsb pdb:5LPL|rcsb pdb:5MME|rcsb pdb:5MMG|rcsb pdb:5MPK|rcsb pdb:5MPN|rcsb pdb:5MPZ|rcsb pdb:5MQE|rcsb pdb:5MQG|rcsb pdb:5MQK|rcsb pdb:5NLK|rcsb pdb:5NRW|rcsb pdb:5NU3|rcsb pdb:5OWK|rcsb pdb:5SVH|rcsb pdb:5TB6|rcsb pdb:5W0E|rcsb pdb:5W0F|rcsb pdb:5W0L|rcsb pdb:5W0Q|rcsb pdb:5XXH|rcsb pdb:6ALB|rcsb pdb:6ALC|rcsb pdb:6AXQ|reactome:R-HSA-9707564|reactome:R-HSA-9707616|reactome:R-HSA-9617629|dip:DIP-952N	refseq:XP_011514460.1|refseq:XP_011514461.1|refseq:XP_011514462.1|refseq:XP_011514463.1|refseq:XP_011514464.1|refseq:XP_011514465.1|refseq:XP_011514466.1|ensembl:ENSG00000128604(gene)|ensembl:ENST00000249375(transcript)|ensembl:ENST00000402030(transcript)|ensembl:ENST00000473745(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002376"(immune system process)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006954"(inflammatory response)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032481"(positive regulation of type I interferon production)|go:"GO:0032494"(response to peptidoglycan)|go:"GO:0032495"(response to muramyl dipeptide)|go:"GO:0032727"(positive regulation of interferon-alpha production)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0032735"(positive regulation of interleukin-12 production)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051607"(defense response to virus)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001346(Interferon regulatory factor)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR017855(SMAD domain-like)|interpro:IPR019471|interpro:IPR019817|interpro:IPR029838|interpro:IPR036388|interpro:IPR036390|rcsb pdb:3DSH|reactome:R-HSA-877300|reactome:R-HSA-909733|go:"GO:0000785"(chromatin)|refseq:NP_001092097.2|refseq:NP_001092099.1|refseq:NP_001092100.1|refseq:NP_001229381.1|refseq:NP_116032.1|ensembl:ENST00000619830|ensembl:ENSP00000483292|ensembl:ENSP00000249375|ensembl:ENST00000357234|ensembl:ENSP00000349770|ensembl:ENSP00000385352|ensembl:ENST00000465603|ensembl:ENSP00000418534|ensembl:ENSP00000419149|ensembl:ENST00000477535|ensembl:ENSP00000419950|ensembl:ENST00000489702|ensembl:ENSP00000418037|refseq:NP_001334857.1|refseq:XP_006716037.1|dip:DIP-46348N|refseq:XP_005250374.1	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/06	2017/08/10	rogid:WWX7TFIpcDwoR5f5Sm1eQ6nma1E9606	rogid:SK3XmPMzlr9XxUpbVe89qzk8pnM9606	rigid:Ny4/NA8ZhhseATSXt2asD7bujHo	false	binding-associated region:2067-2112	binding-associated region:222-467	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q92793	uniprotkb:Q13568	intact:EBI-81215|ensembl:ENSP00000262367|uniprotkb:O00147|uniprotkb:Q16376|uniprotkb:D3DUC9|uniprotkb:Q4LE28	intact:EBI-3931258|uniprotkb:E7EQ16|uniprotkb:Q64GB1|uniprotkb:Q9BQF0|uniprotkb:Q64GB2|intact:EBI-28983960|ensembl:ENSP00000249375|ensembl:ENSP00000385352|ensembl:ENSP00000419149|uniprotkb:A4D1J8|uniprotkb:A8DUA8|uniprotkb:A8DUA9|uniprotkb:Q6RCM8|uniprotkb:E7EW54|uniprotkb:Q64GA9|uniprotkb:Q1A7B4	psi-mi:cbp_human(display_long)|uniprotkb:CREBBP(gene name)|psi-mi:CREBBP(display_short)|uniprotkb:CBP(gene name synonym)|uniprotkb:Histone lysine acetyltransferase CREBBP(gene name synonym)|uniprotkb:Protein-lysine acetyltransferase CREBBP(gene name synonym)	psi-mi:irf5_human(display_long)|uniprotkb:IRF5(gene name)|psi-mi:IRF5(display_short)	psi-mi:"MI:0065"(isothermal titration calorimetry)	Chen et al. (2008)	pubmed:18836453|doi:10.1038/nsmb.1496|imex:IM-9614	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15731757|imex:IM-9614-6|dip:DIP-88315E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000005339(gene)|ensembl:ENST00000262367(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0000785"(chromatin)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0001666"(response to hypoxia)|go:"GO:0002039"(p53 binding)|go:"GO:0002223"(stimulatory C-type lectin receptor signaling pathway)|go:"GO:0003682"(chromatin binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006473"(protein acetylation)|go:"GO:0007165"(signal transduction)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0016407"(acetyltransferase activity)|go:"GO:0016573"(histone acetylation)|go:"GO:0016604"(nuclear body)|go:"GO:0018076"(N-terminal peptidyl-lysine acetylation)|go:"GO:0030511"(positive regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031648"(protein destabilization)|go:"GO:0034212"(peptide N-acetyltransferase activity)|go:"GO:0034644"(cellular response to UV)|go:"GO:0042592"(homeostatic process)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0043426"(MRF binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048511"(rhythmic process)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0061733"(peptide-lysine-N-acetyltransferase activity)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:1900034"(regulation of cellular response to heat)|go:"GO:1990258"(histone glutamine methylation)|interpro:IPR000197(Zinc finger, TAZ-type)|interpro:IPR000433(Zinc finger, ZZ-type)|interpro:IPR001487(Bromodomain)|interpro:IPR003101(Coactivator CBP, KIX)|interpro:IPR009110(Nuclear receptor coactivator, interlocking)|interpro:IPR010303(Protein of unknown function DUF902, CREBbp)|rcsb pdb:1WO7|rcsb pdb:1ZOQ|rcsb pdb:2D82|rcsb pdb:2KJE|rcsb pdb:2KWF|rcsb pdb:2L84|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013178(H3K56 histone acetylation protein, RTT109)|interpro:IPR014744(Nuclear receptor coactivator, CREB-bp-like, interlocking)|interpro:IPR018359|interpro:IPR031162|interpro:IPR035898|interpro:IPR036427|interpro:IPR036529|interpro:IPR037073|interpro:IPR038547|interpro:IPR043145|mint:Q92793|rcsb pdb:1JSP|rcsb pdb:1LIQ|rcsb pdb:1RDT|rcsb pdb:1WO3|rcsb pdb:1WO4|rcsb pdb:1WO5|rcsb pdb:1WO6|rcsb pdb:2L85|rcsb pdb:2LXT|rcsb pdb:2LXS|rcsb pdb:3DWY|rcsb pdb:2N1A|rcsb pdb:3P1C|rcsb pdb:3P1D|refseq:NP_001073315.1|refseq:NP_004371.2|rcsb pdb:3P1E|rcsb pdb:3P1F|rcsb pdb:2RNY|rcsb pdb:6AY3|rcsb pdb:6AY5|rcsb pdb:6DMK|rcsb pdb:6ES5|rcsb pdb:6ES6|rcsb pdb:6ES7|rcsb pdb:6SQM|rcsb pdb:6FQO|rcsb pdb:6SXX|rcsb pdb:6YIJ|rcsb pdb:6YIK|rcsb pdb:6YIL|rcsb pdb:6YIM|rcsb pdb:6FQT|rcsb pdb:7CO1|rcsb pdb:7JFL|rcsb pdb:7JFM|reactome:R-HSA-1234158|rcsb pdb:6FQU|reactome:R-HSA-1368082|reactome:R-HSA-1368108|reactome:R-HSA-1912408|rcsb pdb:6FR0|rcsb pdb:6FRF|rcsb pdb:6M64|rcsb pdb:6QST|reactome:R-HSA-1989781|reactome:R-HSA-201722|reactome:R-HSA-210744|reactome:R-HSA-2122947|reactome:R-HSA-2151201|reactome:R-HSA-2426168|reactome:R-HSA-2644606|rcsb pdb:6SQE|rcsb pdb:6SQF|reactome:R-HSA-2894862|reactome:R-HSA-3134973|reactome:R-HSA-3214847|reactome:R-HSA-3371568|reactome:R-HSA-350054|reactome:R-HSA-381340|reactome:R-HSA-3899300|reactome:R-HSA-400206|reactome:R-HSA-400253|reactome:R-HSA-5617472|reactome:R-HSA-5621575|reactome:R-HSA-6803204|reactome:R-HSA-8866907|reactome:R-HSA-8939246|reactome:R-HSA-8941856|reactome:R-HSA-9013508|reactome:R-HSA-9013695|reactome:R-HSA-9018519|reactome:R-HSA-918233|reactome:R-HSA-933541|reactome:R-HSA-9614657|rcsb pdb:3SVH|rcsb pdb:4A9K|rcsb pdb:4N3W|rcsb pdb:4N4F|rcsb pdb:4NR4|rcsb pdb:4NR5|rcsb pdb:4NR6|rcsb pdb:4NR7|rcsb pdb:4NYV|rcsb pdb:4NYW|rcsb pdb:4NYX|rcsb pdb:4OUF|rcsb pdb:4TQN|rcsb pdb:4TS8|rcsb pdb:4WHU|rcsb pdb:4YK0|rcsb pdb:5CGP|rcsb pdb:5DBM|rcsb pdb:5EIC|rcsb pdb:5ENG|rcsb pdb:5EP7|rcsb pdb:5GH9|rcsb pdb:5H85|rcsb pdb:5I83|rcsb pdb:5I86|rcsb pdb:5I89|rcsb pdb:5I8B|rcsb pdb:5I8G|rcsb pdb:5J0D|rcsb pdb:5JEM|rcsb pdb:5KTU|rcsb pdb:5KTW|rcsb pdb:5KTX|rcsb pdb:5LPJ|rcsb pdb:5LPL|rcsb pdb:5MME|rcsb pdb:5MMG|rcsb pdb:5MPK|rcsb pdb:5MPN|rcsb pdb:5MPZ|rcsb pdb:5MQE|rcsb pdb:5MQG|rcsb pdb:5MQK|rcsb pdb:5NLK|rcsb pdb:5NRW|rcsb pdb:5NU3|rcsb pdb:5OWK|rcsb pdb:5SVH|rcsb pdb:5TB6|rcsb pdb:5W0E|rcsb pdb:5W0F|rcsb pdb:5W0L|rcsb pdb:5W0Q|rcsb pdb:5XXH|rcsb pdb:6ALB|rcsb pdb:6ALC|rcsb pdb:6AXQ|reactome:R-HSA-9707564|reactome:R-HSA-9707616|reactome:R-HSA-9617629|dip:DIP-952N	refseq:XP_011514460.1|refseq:XP_011514461.1|refseq:XP_011514462.1|refseq:XP_011514463.1|refseq:XP_011514464.1|refseq:XP_011514465.1|refseq:XP_011514466.1|ensembl:ENSG00000128604(gene)|ensembl:ENST00000249375(transcript)|ensembl:ENST00000402030(transcript)|ensembl:ENST00000473745(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002376"(immune system process)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006954"(inflammatory response)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032481"(positive regulation of type I interferon production)|go:"GO:0032494"(response to peptidoglycan)|go:"GO:0032495"(response to muramyl dipeptide)|go:"GO:0032727"(positive regulation of interferon-alpha production)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0032735"(positive regulation of interleukin-12 production)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051607"(defense response to virus)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001346(Interferon regulatory factor)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR017855(SMAD domain-like)|interpro:IPR019471|interpro:IPR019817|interpro:IPR029838|interpro:IPR036388|interpro:IPR036390|rcsb pdb:3DSH|reactome:R-HSA-877300|reactome:R-HSA-909733|go:"GO:0000785"(chromatin)|refseq:NP_001092097.2|refseq:NP_001092099.1|refseq:NP_001092100.1|refseq:NP_001229381.1|refseq:NP_116032.1|ensembl:ENST00000619830|ensembl:ENSP00000483292|ensembl:ENSP00000249375|ensembl:ENST00000357234|ensembl:ENSP00000349770|ensembl:ENSP00000385352|ensembl:ENST00000465603|ensembl:ENSP00000418534|ensembl:ENSP00000419149|ensembl:ENST00000477535|ensembl:ENSP00000419950|ensembl:ENST00000489702|ensembl:ENSP00000418037|refseq:NP_001334857.1|refseq:XP_006716037.1|dip:DIP-46348N|refseq:XP_005250374.1	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/06	2017/08/10	rogid:WWX7TFIpcDwoR5f5Sm1eQ6nma1E9606	rogid:SK3XmPMzlr9XxUpbVe89qzk8pnM9606	rigid:Ny4/NA8ZhhseATSXt2asD7bujHo	false	binding-associated region:2067-2112	binding-associated region:222-467	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q13568	uniprotkb:Q13568	intact:EBI-3931258|uniprotkb:E7EQ16|uniprotkb:Q64GB1|uniprotkb:Q9BQF0|uniprotkb:Q64GB2|intact:EBI-28983960|ensembl:ENSP00000249375|ensembl:ENSP00000385352|ensembl:ENSP00000419149|uniprotkb:A4D1J8|uniprotkb:A8DUA8|uniprotkb:A8DUA9|uniprotkb:Q6RCM8|uniprotkb:E7EW54|uniprotkb:Q64GA9|uniprotkb:Q1A7B4	intact:EBI-3931258|uniprotkb:E7EQ16|uniprotkb:Q64GB1|uniprotkb:Q9BQF0|uniprotkb:Q64GB2|intact:EBI-28983960|ensembl:ENSP00000249375|ensembl:ENSP00000385352|ensembl:ENSP00000419149|uniprotkb:A4D1J8|uniprotkb:A8DUA8|uniprotkb:A8DUA9|uniprotkb:Q6RCM8|uniprotkb:E7EW54|uniprotkb:Q64GA9|uniprotkb:Q1A7B4	psi-mi:irf5_human(display_long)|uniprotkb:IRF5(gene name)|psi-mi:IRF5(display_short)	psi-mi:irf5_human(display_long)|uniprotkb:IRF5(gene name)|psi-mi:IRF5(display_short)	psi-mi:"MI:0071"(molecular sieving)	Chen et al. (2008)	pubmed:18836453|doi:10.1038/nsmb.1496|imex:IM-9614	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15731778|imex:IM-9614-4|dip:DIP-88316E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011514460.1|refseq:XP_011514461.1|refseq:XP_011514462.1|refseq:XP_011514463.1|refseq:XP_011514464.1|refseq:XP_011514465.1|refseq:XP_011514466.1|ensembl:ENSG00000128604(gene)|ensembl:ENST00000249375(transcript)|ensembl:ENST00000402030(transcript)|ensembl:ENST00000473745(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002376"(immune system process)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006954"(inflammatory response)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032481"(positive regulation of type I interferon production)|go:"GO:0032494"(response to peptidoglycan)|go:"GO:0032495"(response to muramyl dipeptide)|go:"GO:0032727"(positive regulation of interferon-alpha production)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0032735"(positive regulation of interleukin-12 production)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051607"(defense response to virus)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001346(Interferon regulatory factor)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR017855(SMAD domain-like)|interpro:IPR019471|interpro:IPR019817|interpro:IPR029838|interpro:IPR036388|interpro:IPR036390|rcsb pdb:3DSH|reactome:R-HSA-877300|reactome:R-HSA-909733|go:"GO:0000785"(chromatin)|refseq:NP_001092097.2|refseq:NP_001092099.1|refseq:NP_001092100.1|refseq:NP_001229381.1|refseq:NP_116032.1|ensembl:ENST00000619830|ensembl:ENSP00000483292|ensembl:ENSP00000249375|ensembl:ENST00000357234|ensembl:ENSP00000349770|ensembl:ENSP00000385352|ensembl:ENST00000465603|ensembl:ENSP00000418534|ensembl:ENSP00000419149|ensembl:ENST00000477535|ensembl:ENSP00000419950|ensembl:ENST00000489702|ensembl:ENSP00000418037|refseq:NP_001334857.1|refseq:XP_006716037.1|dip:DIP-46348N|refseq:XP_005250374.1	refseq:XP_011514460.1|refseq:XP_011514461.1|refseq:XP_011514462.1|refseq:XP_011514463.1|refseq:XP_011514464.1|refseq:XP_011514465.1|refseq:XP_011514466.1|ensembl:ENSG00000128604(gene)|ensembl:ENST00000249375(transcript)|ensembl:ENST00000402030(transcript)|ensembl:ENST00000473745(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002376"(immune system process)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006954"(inflammatory response)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032481"(positive regulation of type I interferon production)|go:"GO:0032494"(response to peptidoglycan)|go:"GO:0032495"(response to muramyl dipeptide)|go:"GO:0032727"(positive regulation of interferon-alpha production)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0032735"(positive regulation of interleukin-12 production)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051607"(defense response to virus)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001346(Interferon regulatory factor)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR017855(SMAD domain-like)|interpro:IPR019471|interpro:IPR019817|interpro:IPR029838|interpro:IPR036388|interpro:IPR036390|rcsb pdb:3DSH|reactome:R-HSA-877300|reactome:R-HSA-909733|go:"GO:0000785"(chromatin)|refseq:NP_001092097.2|refseq:NP_001092099.1|refseq:NP_001092100.1|refseq:NP_001229381.1|refseq:NP_116032.1|ensembl:ENST00000619830|ensembl:ENSP00000483292|ensembl:ENSP00000249375|ensembl:ENST00000357234|ensembl:ENSP00000349770|ensembl:ENSP00000385352|ensembl:ENST00000465603|ensembl:ENSP00000418534|ensembl:ENSP00000419149|ensembl:ENST00000477535|ensembl:ENSP00000419950|ensembl:ENST00000489702|ensembl:ENSP00000418037|refseq:NP_001334857.1|refseq:XP_006716037.1|dip:DIP-46348N|refseq:XP_005250374.1	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:562(ecolx)|taxid:562(Escherichia coli)	-	2017/08/06	2017/08/10	rogid:SK3XmPMzlr9XxUpbVe89qzk8pnM9606	rogid:SK3XmPMzlr9XxUpbVe89qzk8pnM9606	rigid:0yPIuZwbv1KUnliqV9h+874uR8U	false	binding-associated region:222-467	binding-associated region:222-467	-	0	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q13568	uniprotkb:Q13568	intact:EBI-3931258|uniprotkb:E7EQ16|uniprotkb:Q64GB1|uniprotkb:Q9BQF0|uniprotkb:Q64GB2|intact:EBI-28983960|ensembl:ENSP00000249375|ensembl:ENSP00000385352|ensembl:ENSP00000419149|uniprotkb:A4D1J8|uniprotkb:A8DUA8|uniprotkb:A8DUA9|uniprotkb:Q6RCM8|uniprotkb:E7EW54|uniprotkb:Q64GA9|uniprotkb:Q1A7B4	intact:EBI-3931258|uniprotkb:E7EQ16|uniprotkb:Q64GB1|uniprotkb:Q9BQF0|uniprotkb:Q64GB2|intact:EBI-28983960|ensembl:ENSP00000249375|ensembl:ENSP00000385352|ensembl:ENSP00000419149|uniprotkb:A4D1J8|uniprotkb:A8DUA8|uniprotkb:A8DUA9|uniprotkb:Q6RCM8|uniprotkb:E7EW54|uniprotkb:Q64GA9|uniprotkb:Q1A7B4	psi-mi:irf5_human(display_long)|uniprotkb:IRF5(gene name)|psi-mi:IRF5(display_short)	psi-mi:irf5_human(display_long)|uniprotkb:IRF5(gene name)|psi-mi:IRF5(display_short)	psi-mi:"MI:0028"(cosedimentation in solution)	Chen et al. (2008)	pubmed:18836453|doi:10.1038/nsmb.1496|imex:IM-9614	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15731796|imex:IM-9614-2|dip:DIP-88316E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011514460.1|refseq:XP_011514461.1|refseq:XP_011514462.1|refseq:XP_011514463.1|refseq:XP_011514464.1|refseq:XP_011514465.1|refseq:XP_011514466.1|ensembl:ENSG00000128604(gene)|ensembl:ENST00000249375(transcript)|ensembl:ENST00000402030(transcript)|ensembl:ENST00000473745(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002376"(immune system process)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006954"(inflammatory response)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032481"(positive regulation of type I interferon production)|go:"GO:0032494"(response to peptidoglycan)|go:"GO:0032495"(response to muramyl dipeptide)|go:"GO:0032727"(positive regulation of interferon-alpha production)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0032735"(positive regulation of interleukin-12 production)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051607"(defense response to virus)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001346(Interferon regulatory factor)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR017855(SMAD domain-like)|interpro:IPR019471|interpro:IPR019817|interpro:IPR029838|interpro:IPR036388|interpro:IPR036390|rcsb pdb:3DSH|reactome:R-HSA-877300|reactome:R-HSA-909733|go:"GO:0000785"(chromatin)|refseq:NP_001092097.2|refseq:NP_001092099.1|refseq:NP_001092100.1|refseq:NP_001229381.1|refseq:NP_116032.1|ensembl:ENST00000619830|ensembl:ENSP00000483292|ensembl:ENSP00000249375|ensembl:ENST00000357234|ensembl:ENSP00000349770|ensembl:ENSP00000385352|ensembl:ENST00000465603|ensembl:ENSP00000418534|ensembl:ENSP00000419149|ensembl:ENST00000477535|ensembl:ENSP00000419950|ensembl:ENST00000489702|ensembl:ENSP00000418037|refseq:NP_001334857.1|refseq:XP_006716037.1|dip:DIP-46348N|refseq:XP_005250374.1	refseq:XP_011514460.1|refseq:XP_011514461.1|refseq:XP_011514462.1|refseq:XP_011514463.1|refseq:XP_011514464.1|refseq:XP_011514465.1|refseq:XP_011514466.1|ensembl:ENSG00000128604(gene)|ensembl:ENST00000249375(transcript)|ensembl:ENST00000402030(transcript)|ensembl:ENST00000473745(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002376"(immune system process)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006954"(inflammatory response)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032481"(positive regulation of type I interferon production)|go:"GO:0032494"(response to peptidoglycan)|go:"GO:0032495"(response to muramyl dipeptide)|go:"GO:0032727"(positive regulation of interferon-alpha production)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0032735"(positive regulation of interleukin-12 production)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051607"(defense response to virus)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001346(Interferon regulatory factor)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR017855(SMAD domain-like)|interpro:IPR019471|interpro:IPR019817|interpro:IPR029838|interpro:IPR036388|interpro:IPR036390|rcsb pdb:3DSH|reactome:R-HSA-877300|reactome:R-HSA-909733|go:"GO:0000785"(chromatin)|refseq:NP_001092097.2|refseq:NP_001092099.1|refseq:NP_001092100.1|refseq:NP_001229381.1|refseq:NP_116032.1|ensembl:ENST00000619830|ensembl:ENSP00000483292|ensembl:ENSP00000249375|ensembl:ENST00000357234|ensembl:ENSP00000349770|ensembl:ENSP00000385352|ensembl:ENST00000465603|ensembl:ENSP00000418534|ensembl:ENSP00000419149|ensembl:ENST00000477535|ensembl:ENSP00000419950|ensembl:ENST00000489702|ensembl:ENSP00000418037|refseq:NP_001334857.1|refseq:XP_006716037.1|dip:DIP-46348N|refseq:XP_005250374.1	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:562(ecolx)|taxid:562(Escherichia coli)	-	2017/08/06	2017/08/10	rogid:SK3XmPMzlr9XxUpbVe89qzk8pnM9606	rogid:SK3XmPMzlr9XxUpbVe89qzk8pnM9606	rigid:0yPIuZwbv1KUnliqV9h+874uR8U	false	binding-associated region:222-467	binding-associated region:222-467	-	0	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q92793	uniprotkb:Q13568	intact:EBI-81215|ensembl:ENSP00000262367|uniprotkb:O00147|uniprotkb:Q16376|uniprotkb:D3DUC9|uniprotkb:Q4LE28	intact:EBI-3931258|uniprotkb:E7EQ16|uniprotkb:Q64GB1|uniprotkb:Q9BQF0|uniprotkb:Q64GB2|intact:EBI-28983960|ensembl:ENSP00000249375|ensembl:ENSP00000385352|ensembl:ENSP00000419149|uniprotkb:A4D1J8|uniprotkb:A8DUA8|uniprotkb:A8DUA9|uniprotkb:Q6RCM8|uniprotkb:E7EW54|uniprotkb:Q64GA9|uniprotkb:Q1A7B4	psi-mi:cbp_human(display_long)|uniprotkb:CREBBP(gene name)|psi-mi:CREBBP(display_short)|uniprotkb:CBP(gene name synonym)|uniprotkb:Histone lysine acetyltransferase CREBBP(gene name synonym)|uniprotkb:Protein-lysine acetyltransferase CREBBP(gene name synonym)	psi-mi:irf5_human(display_long)|uniprotkb:IRF5(gene name)|psi-mi:IRF5(display_short)	psi-mi:"MI:0071"(molecular sieving)	Chen et al. (2008)	pubmed:18836453|doi:10.1038/nsmb.1496|imex:IM-9614	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15731814|imex:IM-9614-1|dip:DIP-88315E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000005339(gene)|ensembl:ENST00000262367(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0000785"(chromatin)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0001666"(response to hypoxia)|go:"GO:0002039"(p53 binding)|go:"GO:0002223"(stimulatory C-type lectin receptor signaling pathway)|go:"GO:0003682"(chromatin binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006473"(protein acetylation)|go:"GO:0007165"(signal transduction)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0016407"(acetyltransferase activity)|go:"GO:0016573"(histone acetylation)|go:"GO:0016604"(nuclear body)|go:"GO:0018076"(N-terminal peptidyl-lysine acetylation)|go:"GO:0030511"(positive regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031648"(protein destabilization)|go:"GO:0034212"(peptide N-acetyltransferase activity)|go:"GO:0034644"(cellular response to UV)|go:"GO:0042592"(homeostatic process)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0043426"(MRF binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048511"(rhythmic process)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0061733"(peptide-lysine-N-acetyltransferase activity)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:1900034"(regulation of cellular response to heat)|go:"GO:1990258"(histone glutamine methylation)|interpro:IPR000197(Zinc finger, TAZ-type)|interpro:IPR000433(Zinc finger, ZZ-type)|interpro:IPR001487(Bromodomain)|interpro:IPR003101(Coactivator CBP, KIX)|interpro:IPR009110(Nuclear receptor coactivator, interlocking)|interpro:IPR010303(Protein of unknown function DUF902, CREBbp)|rcsb pdb:1WO7|rcsb pdb:1ZOQ|rcsb pdb:2D82|rcsb pdb:2KJE|rcsb pdb:2KWF|rcsb pdb:2L84|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013178(H3K56 histone acetylation protein, RTT109)|interpro:IPR014744(Nuclear receptor coactivator, CREB-bp-like, interlocking)|interpro:IPR018359|interpro:IPR031162|interpro:IPR035898|interpro:IPR036427|interpro:IPR036529|interpro:IPR037073|interpro:IPR038547|interpro:IPR043145|mint:Q92793|rcsb pdb:1JSP|rcsb pdb:1LIQ|rcsb pdb:1RDT|rcsb pdb:1WO3|rcsb pdb:1WO4|rcsb pdb:1WO5|rcsb pdb:1WO6|rcsb pdb:2L85|rcsb pdb:2LXT|rcsb pdb:2LXS|rcsb pdb:3DWY|rcsb pdb:2N1A|rcsb pdb:3P1C|rcsb pdb:3P1D|refseq:NP_001073315.1|refseq:NP_004371.2|rcsb pdb:3P1E|rcsb pdb:3P1F|rcsb pdb:2RNY|rcsb pdb:6AY3|rcsb pdb:6AY5|rcsb pdb:6DMK|rcsb pdb:6ES5|rcsb pdb:6ES6|rcsb pdb:6ES7|rcsb pdb:6SQM|rcsb pdb:6FQO|rcsb pdb:6SXX|rcsb pdb:6YIJ|rcsb pdb:6YIK|rcsb pdb:6YIL|rcsb pdb:6YIM|rcsb pdb:6FQT|rcsb pdb:7CO1|rcsb pdb:7JFL|rcsb pdb:7JFM|reactome:R-HSA-1234158|rcsb pdb:6FQU|reactome:R-HSA-1368082|reactome:R-HSA-1368108|reactome:R-HSA-1912408|rcsb pdb:6FR0|rcsb pdb:6FRF|rcsb pdb:6M64|rcsb pdb:6QST|reactome:R-HSA-1989781|reactome:R-HSA-201722|reactome:R-HSA-210744|reactome:R-HSA-2122947|reactome:R-HSA-2151201|reactome:R-HSA-2426168|reactome:R-HSA-2644606|rcsb pdb:6SQE|rcsb pdb:6SQF|reactome:R-HSA-2894862|reactome:R-HSA-3134973|reactome:R-HSA-3214847|reactome:R-HSA-3371568|reactome:R-HSA-350054|reactome:R-HSA-381340|reactome:R-HSA-3899300|reactome:R-HSA-400206|reactome:R-HSA-400253|reactome:R-HSA-5617472|reactome:R-HSA-5621575|reactome:R-HSA-6803204|reactome:R-HSA-8866907|reactome:R-HSA-8939246|reactome:R-HSA-8941856|reactome:R-HSA-9013508|reactome:R-HSA-9013695|reactome:R-HSA-9018519|reactome:R-HSA-918233|reactome:R-HSA-933541|reactome:R-HSA-9614657|rcsb pdb:3SVH|rcsb pdb:4A9K|rcsb pdb:4N3W|rcsb pdb:4N4F|rcsb pdb:4NR4|rcsb pdb:4NR5|rcsb pdb:4NR6|rcsb pdb:4NR7|rcsb pdb:4NYV|rcsb pdb:4NYW|rcsb pdb:4NYX|rcsb pdb:4OUF|rcsb pdb:4TQN|rcsb pdb:4TS8|rcsb pdb:4WHU|rcsb pdb:4YK0|rcsb pdb:5CGP|rcsb pdb:5DBM|rcsb pdb:5EIC|rcsb pdb:5ENG|rcsb pdb:5EP7|rcsb pdb:5GH9|rcsb pdb:5H85|rcsb pdb:5I83|rcsb pdb:5I86|rcsb pdb:5I89|rcsb pdb:5I8B|rcsb pdb:5I8G|rcsb pdb:5J0D|rcsb pdb:5JEM|rcsb pdb:5KTU|rcsb pdb:5KTW|rcsb pdb:5KTX|rcsb pdb:5LPJ|rcsb pdb:5LPL|rcsb pdb:5MME|rcsb pdb:5MMG|rcsb pdb:5MPK|rcsb pdb:5MPN|rcsb pdb:5MPZ|rcsb pdb:5MQE|rcsb pdb:5MQG|rcsb pdb:5MQK|rcsb pdb:5NLK|rcsb pdb:5NRW|rcsb pdb:5NU3|rcsb pdb:5OWK|rcsb pdb:5SVH|rcsb pdb:5TB6|rcsb pdb:5W0E|rcsb pdb:5W0F|rcsb pdb:5W0L|rcsb pdb:5W0Q|rcsb pdb:5XXH|rcsb pdb:6ALB|rcsb pdb:6ALC|rcsb pdb:6AXQ|reactome:R-HSA-9707564|reactome:R-HSA-9707616|reactome:R-HSA-9617629|dip:DIP-952N	refseq:XP_011514460.1|refseq:XP_011514461.1|refseq:XP_011514462.1|refseq:XP_011514463.1|refseq:XP_011514464.1|refseq:XP_011514465.1|refseq:XP_011514466.1|ensembl:ENSG00000128604(gene)|ensembl:ENST00000249375(transcript)|ensembl:ENST00000402030(transcript)|ensembl:ENST00000473745(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002376"(immune system process)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006954"(inflammatory response)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032481"(positive regulation of type I interferon production)|go:"GO:0032494"(response to peptidoglycan)|go:"GO:0032495"(response to muramyl dipeptide)|go:"GO:0032727"(positive regulation of interferon-alpha production)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0032735"(positive regulation of interleukin-12 production)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051607"(defense response to virus)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001346(Interferon regulatory factor)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR017855(SMAD domain-like)|interpro:IPR019471|interpro:IPR019817|interpro:IPR029838|interpro:IPR036388|interpro:IPR036390|rcsb pdb:3DSH|reactome:R-HSA-877300|reactome:R-HSA-909733|go:"GO:0000785"(chromatin)|refseq:NP_001092097.2|refseq:NP_001092099.1|refseq:NP_001092100.1|refseq:NP_001229381.1|refseq:NP_116032.1|ensembl:ENST00000619830|ensembl:ENSP00000483292|ensembl:ENSP00000249375|ensembl:ENST00000357234|ensembl:ENSP00000349770|ensembl:ENSP00000385352|ensembl:ENST00000465603|ensembl:ENSP00000418534|ensembl:ENSP00000419149|ensembl:ENST00000477535|ensembl:ENSP00000419950|ensembl:ENST00000489702|ensembl:ENSP00000418037|refseq:NP_001334857.1|refseq:XP_006716037.1|dip:DIP-46348N|refseq:XP_005250374.1	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/06	2017/08/10	rogid:WWX7TFIpcDwoR5f5Sm1eQ6nma1E9606	rogid:SK3XmPMzlr9XxUpbVe89qzk8pnM9606	rigid:Ny4/NA8ZhhseATSXt2asD7bujHo	false	binding-associated region:2067-2112	binding-associated region:222-467	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q13568	uniprotkb:Q13568	intact:EBI-3931258|uniprotkb:E7EQ16|uniprotkb:Q64GB1|uniprotkb:Q9BQF0|uniprotkb:Q64GB2|intact:EBI-28983960|ensembl:ENSP00000249375|ensembl:ENSP00000385352|ensembl:ENSP00000419149|uniprotkb:A4D1J8|uniprotkb:A8DUA8|uniprotkb:A8DUA9|uniprotkb:Q6RCM8|uniprotkb:E7EW54|uniprotkb:Q64GA9|uniprotkb:Q1A7B4	intact:EBI-3931258|uniprotkb:E7EQ16|uniprotkb:Q64GB1|uniprotkb:Q9BQF0|uniprotkb:Q64GB2|intact:EBI-28983960|ensembl:ENSP00000249375|ensembl:ENSP00000385352|ensembl:ENSP00000419149|uniprotkb:A4D1J8|uniprotkb:A8DUA8|uniprotkb:A8DUA9|uniprotkb:Q6RCM8|uniprotkb:E7EW54|uniprotkb:Q64GA9|uniprotkb:Q1A7B4	psi-mi:irf5_human(display_long)|uniprotkb:IRF5(gene name)|psi-mi:IRF5(display_short)	psi-mi:irf5_human(display_long)|uniprotkb:IRF5(gene name)|psi-mi:IRF5(display_short)	psi-mi:"MI:0114"(x-ray crystallography)	Chen et al. (2008)	pubmed:18836453|doi:10.1038/nsmb.1496|imex:IM-9614	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15731836|imex:IM-9614-3|dip:DIP-88316E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011514460.1|refseq:XP_011514461.1|refseq:XP_011514462.1|refseq:XP_011514463.1|refseq:XP_011514464.1|refseq:XP_011514465.1|refseq:XP_011514466.1|ensembl:ENSG00000128604(gene)|ensembl:ENST00000249375(transcript)|ensembl:ENST00000402030(transcript)|ensembl:ENST00000473745(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002376"(immune system process)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006954"(inflammatory response)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032481"(positive regulation of type I interferon production)|go:"GO:0032494"(response to peptidoglycan)|go:"GO:0032495"(response to muramyl dipeptide)|go:"GO:0032727"(positive regulation of interferon-alpha production)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0032735"(positive regulation of interleukin-12 production)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051607"(defense response to virus)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001346(Interferon regulatory factor)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR017855(SMAD domain-like)|interpro:IPR019471|interpro:IPR019817|interpro:IPR029838|interpro:IPR036388|interpro:IPR036390|rcsb pdb:3DSH|reactome:R-HSA-877300|reactome:R-HSA-909733|go:"GO:0000785"(chromatin)|refseq:NP_001092097.2|refseq:NP_001092099.1|refseq:NP_001092100.1|refseq:NP_001229381.1|refseq:NP_116032.1|ensembl:ENST00000619830|ensembl:ENSP00000483292|ensembl:ENSP00000249375|ensembl:ENST00000357234|ensembl:ENSP00000349770|ensembl:ENSP00000385352|ensembl:ENST00000465603|ensembl:ENSP00000418534|ensembl:ENSP00000419149|ensembl:ENST00000477535|ensembl:ENSP00000419950|ensembl:ENST00000489702|ensembl:ENSP00000418037|refseq:NP_001334857.1|refseq:XP_006716037.1|dip:DIP-46348N|refseq:XP_005250374.1	refseq:XP_011514460.1|refseq:XP_011514461.1|refseq:XP_011514462.1|refseq:XP_011514463.1|refseq:XP_011514464.1|refseq:XP_011514465.1|refseq:XP_011514466.1|ensembl:ENSG00000128604(gene)|ensembl:ENST00000249375(transcript)|ensembl:ENST00000402030(transcript)|ensembl:ENST00000473745(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002376"(immune system process)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006954"(inflammatory response)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032481"(positive regulation of type I interferon production)|go:"GO:0032494"(response to peptidoglycan)|go:"GO:0032495"(response to muramyl dipeptide)|go:"GO:0032727"(positive regulation of interferon-alpha production)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0032735"(positive regulation of interleukin-12 production)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051607"(defense response to virus)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001346(Interferon regulatory factor)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR017855(SMAD domain-like)|interpro:IPR019471|interpro:IPR019817|interpro:IPR029838|interpro:IPR036388|interpro:IPR036390|rcsb pdb:3DSH|reactome:R-HSA-877300|reactome:R-HSA-909733|go:"GO:0000785"(chromatin)|refseq:NP_001092097.2|refseq:NP_001092099.1|refseq:NP_001092100.1|refseq:NP_001229381.1|refseq:NP_116032.1|ensembl:ENST00000619830|ensembl:ENSP00000483292|ensembl:ENSP00000249375|ensembl:ENST00000357234|ensembl:ENSP00000349770|ensembl:ENSP00000385352|ensembl:ENST00000465603|ensembl:ENSP00000418534|ensembl:ENSP00000419149|ensembl:ENST00000477535|ensembl:ENSP00000419950|ensembl:ENST00000489702|ensembl:ENSP00000418037|refseq:NP_001334857.1|refseq:XP_006716037.1|dip:DIP-46348N|refseq:XP_005250374.1	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:562(ecolx)|taxid:562(Escherichia coli)	-	2017/08/06	2017/08/10	rogid:SK3XmPMzlr9XxUpbVe89qzk8pnM9606	rogid:SK3XmPMzlr9XxUpbVe89qzk8pnM9606	rigid:0yPIuZwbv1KUnliqV9h+874uR8U	false	binding-associated region:222-467	binding-associated region:222-467	-	0	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)