#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q9ER80	uniprotkb:P32300	intact:EBI-15731539|ensembl:ENSMUSP00000041091|ensembl:ENSMUSP00000147442|ensembl:ENSMUSP00000147521|uniprotkb:Q9D3D6	intact:EBI-2615936|ensembl:ENSMUSP00000050077	psi-mi:rtp4_mouse(display_long)|uniprotkb:Rtp4(gene name)|psi-mi:Rtp4(display_short)|uniprotkb:Ifrg28(gene name synonym)|uniprotkb:28 kDa interferon-responsive protein(gene name synonym)	psi-mi:oprd_mouse(display_long)|uniprotkb:MSL-2(gene name synonym)|uniprotkb:K56(gene name synonym)|uniprotkb:Oprd1(gene name)|psi-mi:Oprd1(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Décaillot et al. (2008)	pubmed:18836069|doi:10.1073/pnas.0804106105|imex:IM-9664	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15731567|imex:IM-9664-1|dip:DIP-88413E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000033355(gene)|ensembl:ENSMUST00000038423(transcript)|ensembl:ENSMUST00000209422(transcript)|ensembl:ENSMUST00000210901(transcript)|go:"GO:0001580"(detection of chemical stimulus involved in sensory perception of bitter taste)|go:"GO:0005737"(cytoplasm)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031849"(olfactory receptor binding)|go:"GO:0051205"(protein insertion into membrane)|go:"GO:0051607"(defense response to virus)|interpro:IPR026096|interpro:IPR026690|interpro:IPR027377|reactome:R-MMU-381753|refseq:NP_075875.3|refseq:XP_006522554.1|dip:DIP-46418N	refseq:NP_038650.3|ensembl:ENSMUSG00000050511(gene)|ensembl:ENSMUST00000056336(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0004985"(G protein-coupled opioid receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007218"(neuropeptide signaling pathway)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030285"(integral component of synaptic vesicle membrane)|go:"GO:0031226"(intrinsic component of plasma membrane)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031982"(vesicle)|go:"GO:0032590"(dendrite membrane)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033612"(receptor serine/threonine kinase binding)|go:"GO:0038003"(G protein-coupled opioid receptor signaling pathway)|go:"GO:0038046"(G protein-coupled enkephalin receptor activity)|go:"GO:0042277"(peptide binding)|go:"GO:0042755"(eating behavior)|go:"GO:0042923"(neuropeptide binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043679"(axon terminus)|go:"GO:0045121"(membrane raft)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0051881"(regulation of mitochondrial membrane potential)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051930"(regulation of sensory perception of pain)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0097237"(cellular response to toxic substance)|go:"GO:0016020"(membrane)|go:"GO:0098992"(neuronal dense core vesicle)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:0099061"(integral component of postsynaptic density membrane)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR000321(Delta opioid receptor)|interpro:IPR001418(Opioid receptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:4EJ4|reactome:R-MMU-375276|reactome:R-MMU-418594|go:"GO:0097444"(spine apparatus)|dip:DIP-46417N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2017/08/06	2017/08/10	rogid:fmTnKikw/dC/Y5xE3GhBm8a+v0810090	rogid:vRlELxpmehNJiVQ1uZf8+HpgQJ410090	rigid:2XLJ65+o8fy8L+i+UmPO5Tcl0GE	false	flag tag:n-n	myc tag:n-n	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
intact:EBI-4399559	uniprotkb:P32300	dip:DIP-24261N	intact:EBI-2615936|ensembl:ENSMUSP00000050077	psi-mi:ubiq_human(display_short)|psi-mi:EBI-4399559(display_long)	psi-mi:oprd_mouse(display_long)|uniprotkb:MSL-2(gene name synonym)|uniprotkb:K56(gene name synonym)|uniprotkb:Oprd1(gene name)|psi-mi:Oprd1(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Décaillot et al. (2008)	pubmed:18836069|doi:10.1073/pnas.0804106105|imex:IM-9664	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15731609|imex:IM-9664-3|dip:DIP-88415E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	uniprotkb:UBIQ_HUMAN(see-also)|refseq:NP_066289.2	refseq:NP_038650.3|ensembl:ENSMUSG00000050511(gene)|ensembl:ENSMUST00000056336(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0004985"(G protein-coupled opioid receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007218"(neuropeptide signaling pathway)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030285"(integral component of synaptic vesicle membrane)|go:"GO:0031226"(intrinsic component of plasma membrane)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031982"(vesicle)|go:"GO:0032590"(dendrite membrane)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033612"(receptor serine/threonine kinase binding)|go:"GO:0038003"(G protein-coupled opioid receptor signaling pathway)|go:"GO:0038046"(G protein-coupled enkephalin receptor activity)|go:"GO:0042277"(peptide binding)|go:"GO:0042755"(eating behavior)|go:"GO:0042923"(neuropeptide binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043679"(axon terminus)|go:"GO:0045121"(membrane raft)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0051881"(regulation of mitochondrial membrane potential)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051930"(regulation of sensory perception of pain)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0097237"(cellular response to toxic substance)|go:"GO:0016020"(membrane)|go:"GO:0098992"(neuronal dense core vesicle)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:0099061"(integral component of postsynaptic density membrane)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR000321(Delta opioid receptor)|interpro:IPR001418(Opioid receptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:4EJ4|reactome:R-MMU-375276|reactome:R-MMU-418594|go:"GO:0097444"(spine apparatus)|dip:DIP-46417N	psi-mi:"MI:0465"(dip)	no-uniprot-update:	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2017/08/06	2017/08/15	rogid:dobaeYpohKyDSnm4fBbcy0ZbYwM9606	rogid:vRlELxpmehNJiVQ1uZf8+HpgQJ410090	rigid:w7DY5+JkUpfp1pAVNXeA6L5q9ds	false	-	myc tag:n-n	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P32300	uniprotkb:P42866	intact:EBI-2615936|ensembl:ENSMUSP00000050077	intact:EBI-5282656|uniprotkb:Q60768|uniprotkb:A1XGX3|uniprotkb:A1XGX4|uniprotkb:A1YAC3|uniprotkb:A1YAC4|uniprotkb:A5H7G2|uniprotkb:Q4U2P4|uniprotkb:Q4U2Q6|uniprotkb:Q548C6|uniprotkb:Q6YC50|uniprotkb:Q8CAN5|uniprotkb:Q8CGW2|uniprotkb:Q8CH73|uniprotkb:Q8CH74|uniprotkb:Q8CH75|uniprotkb:Q8VBU3|uniprotkb:Q8VBU6|uniprotkb:Q8VBX8|uniprotkb:Q8VI69|uniprotkb:Q8VI70|uniprotkb:Q8VI71|uniprotkb:Q8VIN3|uniprotkb:Q8VIN4|uniprotkb:Q8VIN5|uniprotkb:Q8VIN6|uniprotkb:Q8VIP0|uniprotkb:Q8VIP1|uniprotkb:Q9JIY1|uniprotkb:Q9R0D1|uniprotkb:Q9R1L9|uniprotkb:Q9R1M0|ensembl:ENSMUSP00000060590|ensembl:ENSMUSP00000090410|ensembl:ENSMUSP00000101232	psi-mi:oprd_mouse(display_long)|uniprotkb:MSL-2(gene name synonym)|uniprotkb:K56(gene name synonym)|uniprotkb:Oprd1(gene name)|psi-mi:Oprd1(display_short)	psi-mi:oprm_mouse(display_long)|uniprotkb:Oprm1(gene name)|psi-mi:Oprm1(display_short)|uniprotkb:Mor(gene name synonym)|uniprotkb:Oprm(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Décaillot et al. (2008)	pubmed:18836069|doi:10.1073/pnas.0804106105|imex:IM-9664	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15731628|imex:IM-9664-4|dip:DIP-88416E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_038650.3|ensembl:ENSMUSG00000050511(gene)|ensembl:ENSMUST00000056336(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0004985"(G protein-coupled opioid receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007218"(neuropeptide signaling pathway)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030285"(integral component of synaptic vesicle membrane)|go:"GO:0031226"(intrinsic component of plasma membrane)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031982"(vesicle)|go:"GO:0032590"(dendrite membrane)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033612"(receptor serine/threonine kinase binding)|go:"GO:0038003"(G protein-coupled opioid receptor signaling pathway)|go:"GO:0038046"(G protein-coupled enkephalin receptor activity)|go:"GO:0042277"(peptide binding)|go:"GO:0042755"(eating behavior)|go:"GO:0042923"(neuropeptide binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043679"(axon terminus)|go:"GO:0045121"(membrane raft)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0051881"(regulation of mitochondrial membrane potential)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051930"(regulation of sensory perception of pain)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0097237"(cellular response to toxic substance)|go:"GO:0016020"(membrane)|go:"GO:0098992"(neuronal dense core vesicle)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:0099061"(integral component of postsynaptic density membrane)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR000321(Delta opioid receptor)|interpro:IPR001418(Opioid receptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:4EJ4|reactome:R-MMU-375276|reactome:R-MMU-418594|go:"GO:0097444"(spine apparatus)|dip:DIP-46417N	refseq:NP_001291866.1|refseq:NP_001291867.1|refseq:NP_001291877.1|refseq:NP_001291879.1|refseq:NP_001291884.1|refseq:NP_001289722.1|refseq:NP_001289723.1|refseq:NP_001289724.1|refseq:NP_001289725.1|refseq:NP_001034741.1|refseq:XP_017169315.1|refseq:XP_017169316.1|dip:DIP-46148N|ensembl:ENSMUSG00000000766(gene)|ensembl:ENSMUST00000056385(transcript)|ensembl:ENSMUST00000092734(transcript)|ensembl:ENSMUST00000105607(transcript)|go:"GO:0001965"(G-protein alpha-subunit binding)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0004979"(beta-endorphin receptor activity)|go:"GO:0004985"(G protein-coupled opioid receptor activity)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007191"(adenylate cyclase-activating dopamine receptor signaling pathway)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007197"(adenylate cyclase-inhibiting G protein-coupled acetylcholine receptor signaling pathway)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007218"(neuropeptide signaling pathway)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016020"(membrane)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031005"(filamin binding)|go:"GO:0031635"(adenylate cyclase-inhibiting opioid receptor signaling pathway)|go:"GO:0031681"(G-protein beta-subunit binding)|go:"GO:0032100"(positive regulation of appetite)|go:"GO:0032590"(dendrite membrane)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0038003"(G protein-coupled opioid receptor signaling pathway)|go:"GO:0038047"(morphine receptor activity)|go:"GO:0042277"(peptide binding)|go:"GO:0042755"(eating behavior)|go:"GO:0042923"(neuropeptide binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043204"(perikaryon)|go:"GO:0043950"(positive regulation of cAMP-mediated signaling)|go:"GO:0043951"(negative regulation of cAMP-mediated signaling)|go:"GO:0045019"(negative regulation of nitric oxide biosynthetic process)|go:"GO:0045121"(membrane raft)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0045471"(response to ethanol)|go:"GO:0048149"(behavioral response to ethanol)|go:"GO:0050769"(positive regulation of neurogenesis)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051930"(regulation of sensory perception of pain)|go:"GO:0060079"(excitatory postsynaptic potential)|go:"GO:0061358"(negative regulation of Wnt protein secretion)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0080135"(regulation of cellular response to stress)|go:"GO:0097444"(spine apparatus)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:0106072"(negative regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:2000310"(regulation of NMDA receptor activity)|interpro:IPR000105(Mu opioid receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001418(Opioid receptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:4DKL|rcsb pdb:5C1M|rcsb pdb:6DDE|rcsb pdb:6DDF|reactome:R-MMU-111885|reactome:R-MMU-202040|reactome:R-MMU-375276|reactome:R-MMU-418594	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2017/08/06	2017/08/10	rogid:vRlELxpmehNJiVQ1uZf8+HpgQJ410090	rogid:mjWGRgi4S39QR2gNvSpOkMlt/1s10090	rigid:YIizgUQ2dkAOXcoFrBFcruRRBjA	false	myc tag:n-n	ha tag:n-n	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
intact:EBI-4399559	uniprotkb:P42866	dip:DIP-24261N	intact:EBI-5282656|uniprotkb:Q60768|uniprotkb:A1XGX3|uniprotkb:A1XGX4|uniprotkb:A1YAC3|uniprotkb:A1YAC4|uniprotkb:A5H7G2|uniprotkb:Q4U2P4|uniprotkb:Q4U2Q6|uniprotkb:Q548C6|uniprotkb:Q6YC50|uniprotkb:Q8CAN5|uniprotkb:Q8CGW2|uniprotkb:Q8CH73|uniprotkb:Q8CH74|uniprotkb:Q8CH75|uniprotkb:Q8VBU3|uniprotkb:Q8VBU6|uniprotkb:Q8VBX8|uniprotkb:Q8VI69|uniprotkb:Q8VI70|uniprotkb:Q8VI71|uniprotkb:Q8VIN3|uniprotkb:Q8VIN4|uniprotkb:Q8VIN5|uniprotkb:Q8VIN6|uniprotkb:Q8VIP0|uniprotkb:Q8VIP1|uniprotkb:Q9JIY1|uniprotkb:Q9R0D1|uniprotkb:Q9R1L9|uniprotkb:Q9R1M0|ensembl:ENSMUSP00000060590|ensembl:ENSMUSP00000090410|ensembl:ENSMUSP00000101232	psi-mi:ubiq_human(display_short)|psi-mi:EBI-4399559(display_long)	psi-mi:oprm_mouse(display_long)|uniprotkb:Oprm1(gene name)|psi-mi:Oprm1(display_short)|uniprotkb:Mor(gene name synonym)|uniprotkb:Oprm(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Décaillot et al. (2008)	pubmed:18836069|doi:10.1073/pnas.0804106105|imex:IM-9664	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15731649|imex:IM-9664-5|dip:DIP-88414E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	uniprotkb:UBIQ_HUMAN(see-also)|refseq:NP_066289.2	refseq:NP_001291866.1|refseq:NP_001291867.1|refseq:NP_001291877.1|refseq:NP_001291879.1|refseq:NP_001291884.1|refseq:NP_001289722.1|refseq:NP_001289723.1|refseq:NP_001289724.1|refseq:NP_001289725.1|refseq:NP_001034741.1|refseq:XP_017169315.1|refseq:XP_017169316.1|dip:DIP-46148N|ensembl:ENSMUSG00000000766(gene)|ensembl:ENSMUST00000056385(transcript)|ensembl:ENSMUST00000092734(transcript)|ensembl:ENSMUST00000105607(transcript)|go:"GO:0001965"(G-protein alpha-subunit binding)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0004979"(beta-endorphin receptor activity)|go:"GO:0004985"(G protein-coupled opioid receptor activity)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007191"(adenylate cyclase-activating dopamine receptor signaling pathway)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007197"(adenylate cyclase-inhibiting G protein-coupled acetylcholine receptor signaling pathway)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007218"(neuropeptide signaling pathway)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016020"(membrane)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031005"(filamin binding)|go:"GO:0031635"(adenylate cyclase-inhibiting opioid receptor signaling pathway)|go:"GO:0031681"(G-protein beta-subunit binding)|go:"GO:0032100"(positive regulation of appetite)|go:"GO:0032590"(dendrite membrane)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0038003"(G protein-coupled opioid receptor signaling pathway)|go:"GO:0038047"(morphine receptor activity)|go:"GO:0042277"(peptide binding)|go:"GO:0042755"(eating behavior)|go:"GO:0042923"(neuropeptide binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043204"(perikaryon)|go:"GO:0043950"(positive regulation of cAMP-mediated signaling)|go:"GO:0043951"(negative regulation of cAMP-mediated signaling)|go:"GO:0045019"(negative regulation of nitric oxide biosynthetic process)|go:"GO:0045121"(membrane raft)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0045471"(response to ethanol)|go:"GO:0048149"(behavioral response to ethanol)|go:"GO:0050769"(positive regulation of neurogenesis)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051930"(regulation of sensory perception of pain)|go:"GO:0060079"(excitatory postsynaptic potential)|go:"GO:0061358"(negative regulation of Wnt protein secretion)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0080135"(regulation of cellular response to stress)|go:"GO:0097444"(spine apparatus)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:0106072"(negative regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:2000310"(regulation of NMDA receptor activity)|interpro:IPR000105(Mu opioid receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001418(Opioid receptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:4DKL|rcsb pdb:5C1M|rcsb pdb:6DDE|rcsb pdb:6DDF|reactome:R-MMU-111885|reactome:R-MMU-202040|reactome:R-MMU-375276|reactome:R-MMU-418594	psi-mi:"MI:0465"(dip)	no-uniprot-update:	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2017/08/06	2017/08/15	rogid:dobaeYpohKyDSnm4fBbcy0ZbYwM9606	rogid:mjWGRgi4S39QR2gNvSpOkMlt/1s10090	rigid:jbL+AT8qL++GckqBh7QWXUz1jlk	false	-	ha tag:n-n	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9ER80	uniprotkb:P42866	intact:EBI-15731539|ensembl:ENSMUSP00000041091|ensembl:ENSMUSP00000147442|ensembl:ENSMUSP00000147521|uniprotkb:Q9D3D6	intact:EBI-5282656|uniprotkb:Q60768|uniprotkb:A1XGX3|uniprotkb:A1XGX4|uniprotkb:A1YAC3|uniprotkb:A1YAC4|uniprotkb:A5H7G2|uniprotkb:Q4U2P4|uniprotkb:Q4U2Q6|uniprotkb:Q548C6|uniprotkb:Q6YC50|uniprotkb:Q8CAN5|uniprotkb:Q8CGW2|uniprotkb:Q8CH73|uniprotkb:Q8CH74|uniprotkb:Q8CH75|uniprotkb:Q8VBU3|uniprotkb:Q8VBU6|uniprotkb:Q8VBX8|uniprotkb:Q8VI69|uniprotkb:Q8VI70|uniprotkb:Q8VI71|uniprotkb:Q8VIN3|uniprotkb:Q8VIN4|uniprotkb:Q8VIN5|uniprotkb:Q8VIN6|uniprotkb:Q8VIP0|uniprotkb:Q8VIP1|uniprotkb:Q9JIY1|uniprotkb:Q9R0D1|uniprotkb:Q9R1L9|uniprotkb:Q9R1M0|ensembl:ENSMUSP00000060590|ensembl:ENSMUSP00000090410|ensembl:ENSMUSP00000101232	psi-mi:rtp4_mouse(display_long)|uniprotkb:Rtp4(gene name)|psi-mi:Rtp4(display_short)|uniprotkb:Ifrg28(gene name synonym)|uniprotkb:28 kDa interferon-responsive protein(gene name synonym)	psi-mi:oprm_mouse(display_long)|uniprotkb:Oprm1(gene name)|psi-mi:Oprm1(display_short)|uniprotkb:Mor(gene name synonym)|uniprotkb:Oprm(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Décaillot et al. (2008)	pubmed:18836069|doi:10.1073/pnas.0804106105|imex:IM-9664	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15731588|imex:IM-9664-2|dip:DIP-88412E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000033355(gene)|ensembl:ENSMUST00000038423(transcript)|ensembl:ENSMUST00000209422(transcript)|ensembl:ENSMUST00000210901(transcript)|go:"GO:0001580"(detection of chemical stimulus involved in sensory perception of bitter taste)|go:"GO:0005737"(cytoplasm)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031849"(olfactory receptor binding)|go:"GO:0051205"(protein insertion into membrane)|go:"GO:0051607"(defense response to virus)|interpro:IPR026096|interpro:IPR026690|interpro:IPR027377|reactome:R-MMU-381753|refseq:NP_075875.3|refseq:XP_006522554.1|dip:DIP-46418N	refseq:NP_001291866.1|refseq:NP_001291867.1|refseq:NP_001291877.1|refseq:NP_001291879.1|refseq:NP_001291884.1|refseq:NP_001289722.1|refseq:NP_001289723.1|refseq:NP_001289724.1|refseq:NP_001289725.1|refseq:NP_001034741.1|refseq:XP_017169315.1|refseq:XP_017169316.1|dip:DIP-46148N|ensembl:ENSMUSG00000000766(gene)|ensembl:ENSMUST00000056385(transcript)|ensembl:ENSMUST00000092734(transcript)|ensembl:ENSMUST00000105607(transcript)|go:"GO:0001965"(G-protein alpha-subunit binding)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0004979"(beta-endorphin receptor activity)|go:"GO:0004985"(G protein-coupled opioid receptor activity)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007191"(adenylate cyclase-activating dopamine receptor signaling pathway)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007197"(adenylate cyclase-inhibiting G protein-coupled acetylcholine receptor signaling pathway)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007218"(neuropeptide signaling pathway)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016020"(membrane)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031005"(filamin binding)|go:"GO:0031635"(adenylate cyclase-inhibiting opioid receptor signaling pathway)|go:"GO:0031681"(G-protein beta-subunit binding)|go:"GO:0032100"(positive regulation of appetite)|go:"GO:0032590"(dendrite membrane)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0038003"(G protein-coupled opioid receptor signaling pathway)|go:"GO:0038047"(morphine receptor activity)|go:"GO:0042277"(peptide binding)|go:"GO:0042755"(eating behavior)|go:"GO:0042923"(neuropeptide binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043204"(perikaryon)|go:"GO:0043950"(positive regulation of cAMP-mediated signaling)|go:"GO:0043951"(negative regulation of cAMP-mediated signaling)|go:"GO:0045019"(negative regulation of nitric oxide biosynthetic process)|go:"GO:0045121"(membrane raft)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0045471"(response to ethanol)|go:"GO:0048149"(behavioral response to ethanol)|go:"GO:0050769"(positive regulation of neurogenesis)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051930"(regulation of sensory perception of pain)|go:"GO:0060079"(excitatory postsynaptic potential)|go:"GO:0061358"(negative regulation of Wnt protein secretion)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0080135"(regulation of cellular response to stress)|go:"GO:0097444"(spine apparatus)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:0106072"(negative regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:2000310"(regulation of NMDA receptor activity)|interpro:IPR000105(Mu opioid receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001418(Opioid receptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:4DKL|rcsb pdb:5C1M|rcsb pdb:6DDE|rcsb pdb:6DDF|reactome:R-MMU-111885|reactome:R-MMU-202040|reactome:R-MMU-375276|reactome:R-MMU-418594	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2017/08/06	2017/08/10	rogid:fmTnKikw/dC/Y5xE3GhBm8a+v0810090	rogid:mjWGRgi4S39QR2gNvSpOkMlt/1s10090	rigid:5DgO1I1B6pUT7I//fm3Syo8Fq8E	false	-	sufficient binding region:340-372|flag tag:n-n	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9ER80	uniprotkb:P32300	intact:EBI-15731539|ensembl:ENSMUSP00000041091|ensembl:ENSMUSP00000147442|ensembl:ENSMUSP00000147521|uniprotkb:Q9D3D6	intact:EBI-2615936|ensembl:ENSMUSP00000050077	psi-mi:rtp4_mouse(display_long)|uniprotkb:Rtp4(gene name)|psi-mi:Rtp4(display_short)|uniprotkb:Ifrg28(gene name synonym)|uniprotkb:28 kDa interferon-responsive protein(gene name synonym)	psi-mi:oprd_mouse(display_long)|uniprotkb:MSL-2(gene name synonym)|uniprotkb:K56(gene name synonym)|uniprotkb:Oprd1(gene name)|psi-mi:Oprd1(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Décaillot et al. (2008)	pubmed:18836069|doi:10.1073/pnas.0804106105|imex:IM-9664	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15731668|imex:IM-9664-6|dip:DIP-88413E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000033355(gene)|ensembl:ENSMUST00000038423(transcript)|ensembl:ENSMUST00000209422(transcript)|ensembl:ENSMUST00000210901(transcript)|go:"GO:0001580"(detection of chemical stimulus involved in sensory perception of bitter taste)|go:"GO:0005737"(cytoplasm)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031849"(olfactory receptor binding)|go:"GO:0051205"(protein insertion into membrane)|go:"GO:0051607"(defense response to virus)|interpro:IPR026096|interpro:IPR026690|interpro:IPR027377|reactome:R-MMU-381753|refseq:NP_075875.3|refseq:XP_006522554.1|dip:DIP-46418N	refseq:NP_038650.3|ensembl:ENSMUSG00000050511(gene)|ensembl:ENSMUST00000056336(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0004985"(G protein-coupled opioid receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007218"(neuropeptide signaling pathway)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030285"(integral component of synaptic vesicle membrane)|go:"GO:0031226"(intrinsic component of plasma membrane)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031982"(vesicle)|go:"GO:0032590"(dendrite membrane)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033612"(receptor serine/threonine kinase binding)|go:"GO:0038003"(G protein-coupled opioid receptor signaling pathway)|go:"GO:0038046"(G protein-coupled enkephalin receptor activity)|go:"GO:0042277"(peptide binding)|go:"GO:0042755"(eating behavior)|go:"GO:0042923"(neuropeptide binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043679"(axon terminus)|go:"GO:0045121"(membrane raft)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0051881"(regulation of mitochondrial membrane potential)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051930"(regulation of sensory perception of pain)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0097237"(cellular response to toxic substance)|go:"GO:0016020"(membrane)|go:"GO:0098992"(neuronal dense core vesicle)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:0099061"(integral component of postsynaptic density membrane)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR000321(Delta opioid receptor)|interpro:IPR001418(Opioid receptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:4EJ4|reactome:R-MMU-375276|reactome:R-MMU-418594|go:"GO:0097444"(spine apparatus)|dip:DIP-46417N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2017/08/06	2017/08/10	rogid:fmTnKikw/dC/Y5xE3GhBm8a+v0810090	rogid:vRlELxpmehNJiVQ1uZf8+HpgQJ410090	rigid:2XLJ65+o8fy8L+i+UmPO5Tcl0GE	false	flag tag:n-n	myc tag:n-n	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)