#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P35169 uniprotkb:P20081 intact:EBI-19374|uniprotkb:D6VWN7|ensemblfungi:YJR066W intact:EBI-6961|uniprotkb:D6W147|ensemblfungi:YNL135C psi-mi:tor1_yeast(display_long)|uniprotkb:DRR1(gene name synonym)|uniprotkb:TOR1(gene name)|psi-mi:TOR1(display_short)|uniprotkb:YJR066W(locus name)|uniprotkb:J1803(orf name)|uniprotkb:Phosphatidylinositol kinase homolog TOR1(gene name synonym)|uniprotkb:Target of rapamycin kinase 1(gene name synonym)|uniprotkb:Dominant rapamycin resistance protein 1(gene name synonym) psi-mi:fkbp_yeast(display_long)|uniprotkb:RBP1(gene name synonym)|uniprotkb:N1213(orf name)|uniprotkb:N1845(orf name)|uniprotkb:YNL135C(locus name)|uniprotkb:FPR1(gene name)|psi-mi:FPR1(display_short)|uniprotkb:FKB1(gene name synonym)|uniprotkb:Peptidyl-prolyl cis-trans isomerase(gene name synonym)|uniprotkb:Rapamycin-binding protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Neklesa et al. (2008) pubmed:18812505|doi:10.1073/pnas.0807712105|imex:IM-9531 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15730145|imex:IM-9531-2|dip:DIP-88232E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012600.1|sgd:S000003827|rcsb pdb:2KIT|reactome:R-SCE-1257604|reactome:R-SCE-3371571|reactome:R-SCE-389357|reactome:R-SCE-5218920|reactome:R-SCE-6804757|reactome:R-SCE-9639288|ensemblfungi:YJR066W(gene)|ensemblfungi:YJR066W_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006413"(translational initiation)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0010008"(endosome membrane)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0016242"(negative regulation of macroautophagy)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0031929"(TOR signaling)|go:"GO:0031930"(mitochondria-nucleus signaling pathway)|go:"GO:0031931"(TORC1 complex)|go:"GO:0031932"(TORC2 complex)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0034605"(cellular response to heat)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0038202"(TORC1 signaling)|go:"GO:0042254"(ribosome biogenesis)|go:"GO:0042790"(nucleolar large rRNA transcription by RNA polymerase I)|go:"GO:0044387"(negative regulation of protein kinase activity by regulation of protein phosphorylation)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0090153"(regulation of sphingolipid biosynthetic process)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1905356"(regulation of snRNA pseudouridine synthesis)|interpro:IPR000403(Phosphatidylinositol 3- and 4-kinase, catalytic)|interpro:IPR003151(PIK-related kinase, FAT)|interpro:IPR003152(PIK-related kinase, FATC)|interpro:IPR009076(FKBP12-rapamycin-associated protein, FKBP12-rapamycin-binding)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR014009(PIK-related kinase)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR018936|interpro:IPR024585|interpro:IPR026683|interpro:IPR036738|interpro:IPR036940|rcsb pdb:1W1N|rcsb pdb:2KIO|dip:DIP-917N|mint:P35169 refseq:NP_014264.1|sgd:S000005079|dip:DIP-1263N|mint:P20081|ensemblfungi:YNL135C(gene)|ensemblfungi:YNL135C_mRNA(transcript)|go:"GO:0000413"(protein peptidyl-prolyl isomerization)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005527"(macrolide binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006325"(chromatin organization)|go:"GO:0006457"(protein folding)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:1901710"(regulation of homoserine biosynthetic process)|interpro:IPR001179(Peptidyl-prolyl cis-trans isomerase, FKBP-type)|rcsb pdb:1YAT psi-mi:"MI:0465"(dip) crc64:ACB1781B9963BB1E crc64:65C134830D300C06 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/06 2017/08/10 rogid:3aJf92VnNYbaZZj1+i3uk/IvNQI559292 rogid:8afvGSk+mPghtqkVoWd2rHJXXhQ559292 rigid:OMHbKslM6iRGppn7qHCvjUj1fXs false - ha tag:c-c - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P20081 uniprotkb:P32600 intact:EBI-6961|uniprotkb:D6W147|ensemblfungi:YNL135C intact:EBI-19385|uniprotkb:D6VX00|ensemblfungi:YKL203C psi-mi:fkbp_yeast(display_long)|uniprotkb:RBP1(gene name synonym)|uniprotkb:N1213(orf name)|uniprotkb:N1845(orf name)|uniprotkb:YNL135C(locus name)|uniprotkb:FPR1(gene name)|psi-mi:FPR1(display_short)|uniprotkb:FKB1(gene name synonym)|uniprotkb:Peptidyl-prolyl cis-trans isomerase(gene name synonym)|uniprotkb:Rapamycin-binding protein(gene name synonym) psi-mi:tor2_yeast(display_long)|uniprotkb:DRR2(gene name synonym)|uniprotkb:TSC14(gene name synonym)|uniprotkb:YKL203C(locus name)|uniprotkb:TOR2(gene name)|psi-mi:TOR2(display_short)|uniprotkb:Phosphatidylinositol 4-kinase TOR2(gene name synonym)|uniprotkb:Target of rapamycin kinase 2(gene name synonym)|uniprotkb:Dominant rapamycin resistance protein 2(gene name synonym)|uniprotkb:Temperature-sensitive CSG2 suppressor protein 14(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Neklesa et al. (2008) pubmed:18812505|doi:10.1073/pnas.0807712105|imex:IM-9531 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-15730164|imex:IM-9531-3|dip:DIP-88231E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014264.1|sgd:S000005079|dip:DIP-1263N|mint:P20081|ensemblfungi:YNL135C(gene)|ensemblfungi:YNL135C_mRNA(transcript)|go:"GO:0000413"(protein peptidyl-prolyl isomerization)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005527"(macrolide binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006325"(chromatin organization)|go:"GO:0006457"(protein folding)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:1901710"(regulation of homoserine biosynthetic process)|interpro:IPR001179(Peptidyl-prolyl cis-trans isomerase, FKBP-type)|rcsb pdb:1YAT refseq:NP_012719.2|sgd:S000001686|ensemblfungi:YKL203C(gene)|ensemblfungi:YKL203C_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0004430"(1-phosphatidylinositol 4-kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|interpro:IPR000403(Phosphatidylinositol 3- and 4-kinase, catalytic)|interpro:IPR003151(PIK-related kinase, FAT)|interpro:IPR003152(PIK-related kinase, FATC)|interpro:IPR009076(FKBP12-rapamycin-associated protein, FKBP12-rapamycin-binding)|go:"GO:0005739"(mitochondrion)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR014009(PIK-related kinase)|interpro:IPR016024(Armadillo-type fold)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007049"(cell cycle)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0016242"(negative regulation of macroautophagy)|go:"GO:0030950"(establishment or maintenance of actin cytoskeleton polarity)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031929"(TOR signaling)|go:"GO:0031931"(TORC1 complex)|go:"GO:0031932"(TORC2 complex)|go:"GO:0035025"(positive regulation of Rho protein signal transduction)|go:"GO:0038202"(TORC1 signaling)|go:"GO:0042254"(ribosome biogenesis)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045807"(positive regulation of endocytosis)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1905356"(regulation of snRNA pseudouridine synthesis)|go:"GO:2001108"(positive regulation of Rho guanyl-nucleotide exchange factor activity)|interpro:IPR018936|interpro:IPR026683|interpro:IPR036738|interpro:IPR036940|rcsb pdb:6EMK|reactome:R-SCE-1257604|reactome:R-SCE-3371571|reactome:R-SCE-389357|reactome:R-SCE-5218920|reactome:R-SCE-6804757|reactome:R-SCE-9639288|interpro:IPR024585|dip:DIP-2332N|mint:P32600 psi-mi:"MI:0465"(dip) crc64:65C134830D300C06 crc64:F2349690146058CF full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/06 2017/08/10 rogid:8afvGSk+mPghtqkVoWd2rHJXXhQ559292 rogid:7IgrRILayw94y5+JjCP2x5VLJ4g559292 rigid:eSXDIoiRA5cHX08Ny1LzkXvym+k false ha tag:c-c - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P20081 uniprotkb:P35169 intact:EBI-6961|uniprotkb:D6W147|ensemblfungi:YNL135C intact:EBI-19374|uniprotkb:D6VWN7|ensemblfungi:YJR066W psi-mi:fkbp_yeast(display_long)|uniprotkb:RBP1(gene name synonym)|uniprotkb:N1213(orf name)|uniprotkb:N1845(orf name)|uniprotkb:YNL135C(locus name)|uniprotkb:FPR1(gene name)|psi-mi:FPR1(display_short)|uniprotkb:FKB1(gene name synonym)|uniprotkb:Peptidyl-prolyl cis-trans isomerase(gene name synonym)|uniprotkb:Rapamycin-binding protein(gene name synonym) psi-mi:tor1_yeast(display_long)|uniprotkb:DRR1(gene name synonym)|uniprotkb:TOR1(gene name)|psi-mi:TOR1(display_short)|uniprotkb:YJR066W(locus name)|uniprotkb:J1803(orf name)|uniprotkb:Phosphatidylinositol kinase homolog TOR1(gene name synonym)|uniprotkb:Target of rapamycin kinase 1(gene name synonym)|uniprotkb:Dominant rapamycin resistance protein 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Neklesa et al. (2008) pubmed:18812505|doi:10.1073/pnas.0807712105|imex:IM-9531 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-15730164|imex:IM-9531-3|dip:DIP-88231E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014264.1|sgd:S000005079|dip:DIP-1263N|mint:P20081|ensemblfungi:YNL135C(gene)|ensemblfungi:YNL135C_mRNA(transcript)|go:"GO:0000413"(protein peptidyl-prolyl isomerization)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005527"(macrolide binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006325"(chromatin organization)|go:"GO:0006457"(protein folding)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:1901710"(regulation of homoserine biosynthetic process)|interpro:IPR001179(Peptidyl-prolyl cis-trans isomerase, FKBP-type)|rcsb pdb:1YAT refseq:NP_012600.1|sgd:S000003827|rcsb pdb:2KIT|reactome:R-SCE-1257604|reactome:R-SCE-3371571|reactome:R-SCE-389357|reactome:R-SCE-5218920|reactome:R-SCE-6804757|reactome:R-SCE-9639288|ensemblfungi:YJR066W(gene)|ensemblfungi:YJR066W_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006413"(translational initiation)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0010008"(endosome membrane)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0016242"(negative regulation of macroautophagy)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0031929"(TOR signaling)|go:"GO:0031930"(mitochondria-nucleus signaling pathway)|go:"GO:0031931"(TORC1 complex)|go:"GO:0031932"(TORC2 complex)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0034605"(cellular response to heat)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0038202"(TORC1 signaling)|go:"GO:0042254"(ribosome biogenesis)|go:"GO:0042790"(nucleolar large rRNA transcription by RNA polymerase I)|go:"GO:0044387"(negative regulation of protein kinase activity by regulation of protein phosphorylation)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0090153"(regulation of sphingolipid biosynthetic process)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1905356"(regulation of snRNA pseudouridine synthesis)|interpro:IPR000403(Phosphatidylinositol 3- and 4-kinase, catalytic)|interpro:IPR003151(PIK-related kinase, FAT)|interpro:IPR003152(PIK-related kinase, FATC)|interpro:IPR009076(FKBP12-rapamycin-associated protein, FKBP12-rapamycin-binding)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR014009(PIK-related kinase)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR018936|interpro:IPR024585|interpro:IPR026683|interpro:IPR036738|interpro:IPR036940|rcsb pdb:1W1N|rcsb pdb:2KIO|dip:DIP-917N|mint:P35169 psi-mi:"MI:0465"(dip) crc64:65C134830D300C06 crc64:ACB1781B9963BB1E full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/06 2017/08/10 rogid:8afvGSk+mPghtqkVoWd2rHJXXhQ559292 rogid:3aJf92VnNYbaZZj1+i3uk/IvNQI559292 rigid:eSXDIoiRA5cHX08Ny1LzkXvym+k false ha tag:c-c - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P35169 uniprotkb:P20081 intact:EBI-19374|uniprotkb:D6VWN7|ensemblfungi:YJR066W intact:EBI-6961|uniprotkb:D6W147|ensemblfungi:YNL135C psi-mi:tor1_yeast(display_long)|uniprotkb:DRR1(gene name synonym)|uniprotkb:TOR1(gene name)|psi-mi:TOR1(display_short)|uniprotkb:YJR066W(locus name)|uniprotkb:J1803(orf name)|uniprotkb:Phosphatidylinositol kinase homolog TOR1(gene name synonym)|uniprotkb:Target of rapamycin kinase 1(gene name synonym)|uniprotkb:Dominant rapamycin resistance protein 1(gene name synonym) psi-mi:fkbp_yeast(display_long)|uniprotkb:RBP1(gene name synonym)|uniprotkb:N1213(orf name)|uniprotkb:N1845(orf name)|uniprotkb:YNL135C(locus name)|uniprotkb:FPR1(gene name)|psi-mi:FPR1(display_short)|uniprotkb:FKB1(gene name synonym)|uniprotkb:Peptidyl-prolyl cis-trans isomerase(gene name synonym)|uniprotkb:Rapamycin-binding protein(gene name synonym) psi-mi:"MI:0096"(pull down) Neklesa et al. (2008) pubmed:18812505|doi:10.1073/pnas.0807712105|imex:IM-9531 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15730184|imex:IM-9531-1|dip:DIP-88232E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012600.1|sgd:S000003827|rcsb pdb:2KIT|reactome:R-SCE-1257604|reactome:R-SCE-3371571|reactome:R-SCE-389357|reactome:R-SCE-5218920|reactome:R-SCE-6804757|reactome:R-SCE-9639288|ensemblfungi:YJR066W(gene)|ensemblfungi:YJR066W_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006413"(translational initiation)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0010008"(endosome membrane)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0016242"(negative regulation of macroautophagy)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0031929"(TOR signaling)|go:"GO:0031930"(mitochondria-nucleus signaling pathway)|go:"GO:0031931"(TORC1 complex)|go:"GO:0031932"(TORC2 complex)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0034605"(cellular response to heat)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0038202"(TORC1 signaling)|go:"GO:0042254"(ribosome biogenesis)|go:"GO:0042790"(nucleolar large rRNA transcription by RNA polymerase I)|go:"GO:0044387"(negative regulation of protein kinase activity by regulation of protein phosphorylation)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0090153"(regulation of sphingolipid biosynthetic process)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1905356"(regulation of snRNA pseudouridine synthesis)|interpro:IPR000403(Phosphatidylinositol 3- and 4-kinase, catalytic)|interpro:IPR003151(PIK-related kinase, FAT)|interpro:IPR003152(PIK-related kinase, FATC)|interpro:IPR009076(FKBP12-rapamycin-associated protein, FKBP12-rapamycin-binding)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR014009(PIK-related kinase)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR018936|interpro:IPR024585|interpro:IPR026683|interpro:IPR036738|interpro:IPR036940|rcsb pdb:1W1N|rcsb pdb:2KIO|dip:DIP-917N|mint:P35169 refseq:NP_014264.1|sgd:S000005079|dip:DIP-1263N|mint:P20081|ensemblfungi:YNL135C(gene)|ensemblfungi:YNL135C_mRNA(transcript)|go:"GO:0000413"(protein peptidyl-prolyl isomerization)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005527"(macrolide binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006325"(chromatin organization)|go:"GO:0006457"(protein folding)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:1901710"(regulation of homoserine biosynthetic process)|interpro:IPR001179(Peptidyl-prolyl cis-trans isomerase, FKBP-type)|rcsb pdb:1YAT psi-mi:"MI:0465"(dip) crc64:ACB1781B9963BB1E crc64:65C134830D300C06 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/06 2017/08/10 rogid:3aJf92VnNYbaZZj1+i3uk/IvNQI559292 rogid:8afvGSk+mPghtqkVoWd2rHJXXhQ559292 rigid:OMHbKslM6iRGppn7qHCvjUj1fXs false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P32600 uniprotkb:P20081 intact:EBI-19385|uniprotkb:D6VX00|ensemblfungi:YKL203C intact:EBI-6961|uniprotkb:D6W147|ensemblfungi:YNL135C psi-mi:tor2_yeast(display_long)|uniprotkb:DRR2(gene name synonym)|uniprotkb:TSC14(gene name synonym)|uniprotkb:YKL203C(locus name)|uniprotkb:TOR2(gene name)|psi-mi:TOR2(display_short)|uniprotkb:Phosphatidylinositol 4-kinase TOR2(gene name synonym)|uniprotkb:Target of rapamycin kinase 2(gene name synonym)|uniprotkb:Dominant rapamycin resistance protein 2(gene name synonym)|uniprotkb:Temperature-sensitive CSG2 suppressor protein 14(gene name synonym) psi-mi:fkbp_yeast(display_long)|uniprotkb:RBP1(gene name synonym)|uniprotkb:N1213(orf name)|uniprotkb:N1845(orf name)|uniprotkb:YNL135C(locus name)|uniprotkb:FPR1(gene name)|psi-mi:FPR1(display_short)|uniprotkb:FKB1(gene name synonym)|uniprotkb:Peptidyl-prolyl cis-trans isomerase(gene name synonym)|uniprotkb:Rapamycin-binding protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Neklesa et al. (2008) pubmed:18812505|doi:10.1073/pnas.0807712105|imex:IM-9531 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15730201|imex:IM-9531-4|dip:DIP-2691E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012719.2|sgd:S000001686|ensemblfungi:YKL203C(gene)|ensemblfungi:YKL203C_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0004430"(1-phosphatidylinositol 4-kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|interpro:IPR000403(Phosphatidylinositol 3- and 4-kinase, catalytic)|interpro:IPR003151(PIK-related kinase, FAT)|interpro:IPR003152(PIK-related kinase, FATC)|interpro:IPR009076(FKBP12-rapamycin-associated protein, FKBP12-rapamycin-binding)|go:"GO:0005739"(mitochondrion)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR014009(PIK-related kinase)|interpro:IPR016024(Armadillo-type fold)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007049"(cell cycle)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0016242"(negative regulation of macroautophagy)|go:"GO:0030950"(establishment or maintenance of actin cytoskeleton polarity)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031929"(TOR signaling)|go:"GO:0031931"(TORC1 complex)|go:"GO:0031932"(TORC2 complex)|go:"GO:0035025"(positive regulation of Rho protein signal transduction)|go:"GO:0038202"(TORC1 signaling)|go:"GO:0042254"(ribosome biogenesis)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045807"(positive regulation of endocytosis)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1905356"(regulation of snRNA pseudouridine synthesis)|go:"GO:2001108"(positive regulation of Rho guanyl-nucleotide exchange factor activity)|interpro:IPR018936|interpro:IPR026683|interpro:IPR036738|interpro:IPR036940|rcsb pdb:6EMK|reactome:R-SCE-1257604|reactome:R-SCE-3371571|reactome:R-SCE-389357|reactome:R-SCE-5218920|reactome:R-SCE-6804757|reactome:R-SCE-9639288|interpro:IPR024585|dip:DIP-2332N|mint:P32600 refseq:NP_014264.1|sgd:S000005079|dip:DIP-1263N|mint:P20081|ensemblfungi:YNL135C(gene)|ensemblfungi:YNL135C_mRNA(transcript)|go:"GO:0000413"(protein peptidyl-prolyl isomerization)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005527"(macrolide binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006325"(chromatin organization)|go:"GO:0006457"(protein folding)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:1901710"(regulation of homoserine biosynthetic process)|interpro:IPR001179(Peptidyl-prolyl cis-trans isomerase, FKBP-type)|rcsb pdb:1YAT psi-mi:"MI:0465"(dip) crc64:F2349690146058CF crc64:65C134830D300C06 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/06 2017/08/10 rogid:7IgrRILayw94y5+JjCP2x5VLJ4g559292 rogid:8afvGSk+mPghtqkVoWd2rHJXXhQ559292 rigid:XBz/eCu4CXeFnJIoyK6W0u9nim0 false - ha tag:c-c - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot)