#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q16795 uniprotkb:Q9NTG7 intact:EBI-1045087|uniprotkb:Q14076|uniprotkb:Q2NKX0|ensembl:ENSP00000266544 intact:EBI-724621|uniprotkb:Q9Y6E8|ensembl:ENSP00000372191|uniprotkb:B7Z5U6 psi-mi:ndua9_human(display_long)|uniprotkb:NADH-ubiquinone oxidoreductase 39 kDa subunit(gene name synonym)|uniprotkb:Complex I-39kD(gene name synonym)|uniprotkb:NDUFA9(gene name)|psi-mi:NDUFA9(display_short)|uniprotkb:NDUFS2L(gene name synonym) psi-mi:sir3_human(display_long)|uniprotkb:SIRT3(gene name)|psi-mi:SIRT3(display_short)|uniprotkb:SIR2L3(gene name synonym)|uniprotkb:SIR2-like protein 3(gene name synonym)|uniprotkb:Regulatory protein SIR2 homolog 3(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ahn et al. (2008) pubmed:18794531|doi:10.1073/pnas.0803790105|imex:IM-14330 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15728715|imex:IM-14330-1|dip:DIP-103250E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004993.1|ensembl:ENSG00000139180(gene)|ensembl:ENST00000266544(transcript)|go:"GO:0003954"(NADH dehydrogenase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0006814"(sodium ion transport)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0009749"(response to glucose)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:1901006"(ubiquinone-6 biosynthetic process)|interpro:IPR001509(NAD-dependent epimerase/dehydratase)|interpro:IPR036291|mint:Q16795|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|dip:DIP-38526N refseq:NP_001017524.1|refseq:NP_036371.1|ensembl:ENSG00000142082(gene)|ensembl:ENST00000382743(transcript)|go:"GO:0003950"(NAD+ ADP-ribosyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006471"(protein ADP-ribosylation)|go:"GO:0006476"(protein deacetylation)|go:"GO:0007568"(aging)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009060"(aerobic respiration)|go:"GO:0017136"(NAD-dependent histone deacetylase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034979"(NAD-dependent protein deacetylase activity)|go:"GO:0034983"(peptidyl-lysine deacetylation)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0070403"(NAD+ binding)|go:"GO:1901671"(positive regulation of superoxide dismutase activity)|go:"GO:1902553"(positive regulation of catalase activity)|go:"GO:2000304"(positive regulation of ceramide biosynthetic process)|go:"GO:2000378"(negative regulation of reactive oxygen species metabolic process)|interpro:IPR003000(NAD-dependent histone deacetylase, silent information regulator Sir2)|interpro:IPR026590|interpro:IPR026591|interpro:IPR029035|go:"GO:0043565"(sequence-specific DNA binding)|rcsb pdb:3GLR|rcsb pdb:3GLS|rcsb pdb:3GLT|rcsb pdb:3GLU|rcsb pdb:4BN4|rcsb pdb:4BN5|rcsb pdb:4BV3|rcsb pdb:4BVB|rcsb pdb:4BVF|rcsb pdb:4BVG|rcsb pdb:4BVH|rcsb pdb:4C78|rcsb pdb:4C7B|rcsb pdb:4FVT|rcsb pdb:4FZ3|rcsb pdb:4HD8|rcsb pdb:4JSR|rcsb pdb:4JT8|rcsb pdb:4JT9|rcsb pdb:4O8Z|rcsb pdb:5BWN|rcsb pdb:5BWO|rcsb pdb:5D7N|rcsb pdb:5H4D|rcsb pdb:5Y4H|rcsb pdb:5YTK|rcsb pdb:5Z93|rcsb pdb:5Z94|rcsb pdb:5ZGC|rcsb pdb:6ISO|reactome:R-HSA-2151201|reactome:R-HSA-9615017|reactome:R-HSA-9617629|rcsb pdb:4BVE|refseq:XP_016872919.1|dip:DIP-46861N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/06 2017/08/10 rogid:eM2zUsbdjMEILIcUedVOyEMwAzU9606 rogid:KGNwfCABi61filBQeIU5v5n51kE9606 rigid:uQ5EXPavHJppQ6Lf7u8FJbkwUCY false - myc tag:n-n - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot)