#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q8VGC3-2 uniprotkb:Q8VGC3-2 intact:EBI-15685453 intact:EBI-15685453 psi-mi:q8vgc3-2(display_long)|uniprotkb:Cacnb2(gene name)|psi-mi:Cacnb2(display_short)|uniprotkb:Cacnlb2(gene name synonym)|uniprotkb:Calcium channel voltage-dependent subunit beta 2(gene name synonym) psi-mi:q8vgc3-2(display_long)|uniprotkb:Cacnb2(gene name)|psi-mi:Cacnb2(display_short)|uniprotkb:Cacnlb2(gene name synonym)|uniprotkb:Calcium channel voltage-dependent subunit beta 2(gene name synonym) psi-mi:"MI:0071"(molecular sieving) Gonzalez-Gutierrez et al. (2008) pubmed:18776052|doi:10.1073/pnas.0806558105|imex:IM-9656 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15727404|imex:IM-9656-3|dip:DIP-88399E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-1038896(isoform-parent) intact:EBI-1038896(isoform-parent) psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/06 2017/08/10 rogid:rDSercniN96H3w9KSb01f8yn5B810116 rogid:rDSercniN96H3w9KSb01f8yn5B810116 rigid:/rCsCtppH4pttWgVm3HWmrs5JsY false binding-associated region:201-422 binding-associated region:201-422 - 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P54283 uniprotkb:P54283 intact:EBI-349245 intact:EBI-349245 psi-mi:cacb1_rat(display_long)|uniprotkb:Cacnb1(gene name)|psi-mi:Cacnb1(display_short)|uniprotkb:Cacnlb1(gene name synonym)|uniprotkb:Calcium channel voltage-dependent subunit beta 1(gene name synonym) psi-mi:cacb1_rat(display_long)|uniprotkb:Cacnb1(gene name)|psi-mi:Cacnb1(display_short)|uniprotkb:Cacnlb1(gene name synonym)|uniprotkb:Calcium channel voltage-dependent subunit beta 1(gene name synonym) psi-mi:"MI:0071"(molecular sieving) Gonzalez-Gutierrez et al. (2008) pubmed:18776052|doi:10.1073/pnas.0806558105|imex:IM-9656 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15727502|imex:IM-9656-5|dip:DIP-88400E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rgd:68382|refseq:NP_059042.1|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0008331"(high voltage-gated calcium channel activity)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030315"(T-tubule)|go:"GO:0042802"(identical protein binding)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0098793"(presynapse)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1901385"(regulation of voltage-gated calcium channel activity)|go:"GO:1904646"(cellular response to amyloid-beta)|interpro:IPR000584(Voltage-dependent calcium channel, L-type, beta subunit)|interpro:IPR001452(Src homology-3)|interpro:IPR005443(Voltage-dependent calcium channel, L-type, beta-1 subunit)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR027417|interpro:IPR036028|go:"GO:1902514"(regulation of calcium ion transmembrane transport via high voltage-gated calcium channel)|dip:DIP-33255N|reactome:R-RNO-112308|reactome:R-RNO-5576892|reactome:R-RNO-5576893 rgd:68382|refseq:NP_059042.1|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0008331"(high voltage-gated calcium channel activity)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030315"(T-tubule)|go:"GO:0042802"(identical protein binding)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0098793"(presynapse)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1901385"(regulation of voltage-gated calcium channel activity)|go:"GO:1904646"(cellular response to amyloid-beta)|interpro:IPR000584(Voltage-dependent calcium channel, L-type, beta subunit)|interpro:IPR001452(Src homology-3)|interpro:IPR005443(Voltage-dependent calcium channel, L-type, beta-1 subunit)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR027417|interpro:IPR036028|go:"GO:1902514"(regulation of calcium ion transmembrane transport via high voltage-gated calcium channel)|dip:DIP-33255N|reactome:R-RNO-112308|reactome:R-RNO-5576892|reactome:R-RNO-5576893 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/06 2017/08/10 rogid:oNJoUYe2/9+qncptm5OX7ncSIhc10116 rogid:oNJoUYe2/9+qncptm5OX7ncSIhc10116 rigid:PssSsck4+WEJHWVCRu3SGzksIHE false binding-associated region:209-413 binding-associated region:209-413 - 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P54283 uniprotkb:P54283 intact:EBI-349245 intact:EBI-349245 psi-mi:cacb1_rat(display_long)|uniprotkb:Cacnb1(gene name)|psi-mi:Cacnb1(display_short)|uniprotkb:Cacnlb1(gene name synonym)|uniprotkb:Calcium channel voltage-dependent subunit beta 1(gene name synonym) psi-mi:cacb1_rat(display_long)|uniprotkb:Cacnb1(gene name)|psi-mi:Cacnb1(display_short)|uniprotkb:Cacnlb1(gene name synonym)|uniprotkb:Calcium channel voltage-dependent subunit beta 1(gene name synonym) psi-mi:"MI:0029"(cosedimentation through density gradient) Gonzalez-Gutierrez et al. (2008) pubmed:18776052|doi:10.1073/pnas.0806558105|imex:IM-9656 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15727422|imex:IM-9656-1|dip:DIP-88400E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rgd:68382|refseq:NP_059042.1|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0008331"(high voltage-gated calcium channel activity)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030315"(T-tubule)|go:"GO:0042802"(identical protein binding)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0098793"(presynapse)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1901385"(regulation of voltage-gated calcium channel activity)|go:"GO:1904646"(cellular response to amyloid-beta)|interpro:IPR000584(Voltage-dependent calcium channel, L-type, beta subunit)|interpro:IPR001452(Src homology-3)|interpro:IPR005443(Voltage-dependent calcium channel, L-type, beta-1 subunit)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR027417|interpro:IPR036028|go:"GO:1902514"(regulation of calcium ion transmembrane transport via high voltage-gated calcium channel)|dip:DIP-33255N|reactome:R-RNO-112308|reactome:R-RNO-5576892|reactome:R-RNO-5576893 rgd:68382|refseq:NP_059042.1|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0008331"(high voltage-gated calcium channel activity)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030315"(T-tubule)|go:"GO:0042802"(identical protein binding)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0098793"(presynapse)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1901385"(regulation of voltage-gated calcium channel activity)|go:"GO:1904646"(cellular response to amyloid-beta)|interpro:IPR000584(Voltage-dependent calcium channel, L-type, beta subunit)|interpro:IPR001452(Src homology-3)|interpro:IPR005443(Voltage-dependent calcium channel, L-type, beta-1 subunit)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR027417|interpro:IPR036028|go:"GO:1902514"(regulation of calcium ion transmembrane transport via high voltage-gated calcium channel)|dip:DIP-33255N|reactome:R-RNO-112308|reactome:R-RNO-5576892|reactome:R-RNO-5576893 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/06 2017/08/10 rogid:oNJoUYe2/9+qncptm5OX7ncSIhc10116 rogid:oNJoUYe2/9+qncptm5OX7ncSIhc10116 rigid:PssSsck4+WEJHWVCRu3SGzksIHE false binding-associated region:209-413 binding-associated region:209-413 - 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8VGC3-2 uniprotkb:Q8VGC3-2 intact:EBI-15685453 intact:EBI-15685453 psi-mi:q8vgc3-2(display_long)|uniprotkb:Cacnb2(gene name)|psi-mi:Cacnb2(display_short)|uniprotkb:Cacnlb2(gene name synonym)|uniprotkb:Calcium channel voltage-dependent subunit beta 2(gene name synonym) psi-mi:q8vgc3-2(display_long)|uniprotkb:Cacnb2(gene name)|psi-mi:Cacnb2(display_short)|uniprotkb:Cacnlb2(gene name synonym)|uniprotkb:Calcium channel voltage-dependent subunit beta 2(gene name synonym) psi-mi:"MI:0029"(cosedimentation through density gradient) Gonzalez-Gutierrez et al. (2008) pubmed:18776052|doi:10.1073/pnas.0806558105|imex:IM-9656 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15727484|imex:IM-9656-4|dip:DIP-88399E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-1038896(isoform-parent) intact:EBI-1038896(isoform-parent) psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/06 2017/08/10 rogid:rDSercniN96H3w9KSb01f8yn5B810116 rogid:rDSercniN96H3w9KSb01f8yn5B810116 rigid:/rCsCtppH4pttWgVm3HWmrs5JsY false binding-associated region:201-422 binding-associated region:201-422 - 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P15381-1 uniprotkb:Q8VGC3-2 intact:EBI-15727440 intact:EBI-15685453 psi-mi:p15381-1(display_long)|uniprotkb:CACNA1C(gene name)|psi-mi:CACNA1C(display_short)|uniprotkb:CACH2(gene name synonym)|uniprotkb:CACN2(gene name synonym)|uniprotkb:CACNL1A1(gene name synonym)|uniprotkb:CCHL1A1(gene name synonym)|uniprotkb:Calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle(gene name synonym)|uniprotkb:Smooth muscle calcium channel blocker receptor(gene name synonym)|uniprotkb:Voltage-gated calcium channel subunit alpha Cav1.2(gene name synonym)|uniprotkb:CACH2A(isoform synonym) psi-mi:q8vgc3-2(display_long)|uniprotkb:Cacnb2(gene name)|psi-mi:Cacnb2(display_short)|uniprotkb:Cacnlb2(gene name synonym)|uniprotkb:Calcium channel voltage-dependent subunit beta 2(gene name synonym) psi-mi:"MI:0096"(pull down) Gonzalez-Gutierrez et al. (2008) pubmed:18776052|doi:10.1073/pnas.0806558105|imex:IM-9656 taxid:9986(rabit)|taxid:9986("Oryctolagus cuniculus (Rabbit)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15727455|imex:IM-9656-2|dip:DIP-88401E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-16354227(isoform-parent) intact:EBI-1038896(isoform-parent) psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/06 2017/08/10 rogid:4PifRtGysoZw+E+GFl0roo58uUs9986 rogid:rDSercniN96H3w9KSb01f8yn5B810116 rigid:eh4Za33JDSnnixjEFEPn2F/afVw false binding-associated region:422-534|glutathione s tranferase tag:?-? binding-associated region:201-422|yellow fluorescent protein tag:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)