#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q9JIY5	uniprotkb:Q99MS3-1	intact:EBI-2365838|uniprotkb:Q9R108|ensembl:ENSMUSP00000087073	intact:EBI-15727082|ensembl:ENSMUSP00000023360	psi-mi:htra2_mouse(display_long)|uniprotkb:Htra2(gene name)|psi-mi:Htra2(display_short)|uniprotkb:Omi(gene name synonym)|uniprotkb:Prss25(gene name synonym)|uniprotkb:High temperature requirement protein A2(gene name synonym)|uniprotkb:Omi stress-regulated endoprotease(gene name synonym)|uniprotkb:Serine proteinase OMI(gene name synonym)|uniprotkb:Serine protease 25(gene name synonym)	psi-mi:q99ms3-1(display_long)|uniprotkb:Mpv17l(gene name)|psi-mi:Mpv17l(display_short)|uniprotkb:M-LP long(isoform synonym)	psi-mi:"MI:0096"(pull down)	Krick et al. (2008)	pubmed:18772386|doi:10.1073/pnas.0801146105|imex:IM-9529	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15727088|imex:IM-9529-1|dip:DIP-88226E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_062726.3|dip:DIP-41272N|ensembl:ENSMUSG00000068329(gene)|ensembl:ENSMUST00000089645(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006508"(proteolysis)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0007568"(aging)|go:"GO:0007628"(adult walking behavior)|go:"GO:0008233"(peptidase activity)|go:"GO:0008236"(serine-type peptidase activity)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0009635"(response to herbicide)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010822"(positive regulation of mitochondrion organization)|go:"GO:0012501"(programmed cell death)|go:"GO:0016020"(membrane)|go:"GO:0019742"(pentacyclic triterpenoid metabolic process)|go:"GO:0030900"(forebrain development)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0034605"(cellular response to heat)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035631"(CD40 receptor complex)|go:"GO:0040014"(regulation of multicellular organism growth)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0044257"(cellular protein catabolic process)|go:"GO:0048666"(neuron development)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0097193"(intrinsic apoptotic signaling pathway)|go:"GO:1904924"(negative regulation of mitophagy in response to mitochondrial depolarization)|go:"GO:1905370"(serine-type endopeptidase complex)|go:"GO:2001241"(positive regulation of extrinsic apoptotic signaling pathway in absence of ligand)|go:"GO:2001269"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001940(Peptidase S1C, HrtA/DegP2/Q/S)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR036034|interpro:IPR041489|mint:Q9JIY5	ensembl:ENSMUSG00000022679(gene)|ensembl:ENSMUST00000023360(transcript)|intact:EBI-15727135(isoform-parent)	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/06	2017/08/10	rogid:hFFaMR4foetALMvFA0cg4KuxjuE10090	rogid:AeFEN4IFmEjcpNcbSOeqfNKIvHA10090	rigid:wJ9VglEtCRj5qO+pH7Nk0ev5Y8E	false	-	glutathione s tranferase tag:?-?	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q99MS3-3	uniprotkb:Q9JIY5	intact:EBI-15727109|ensembl:ENSMUSP00000117826	intact:EBI-2365838|uniprotkb:Q9R108|ensembl:ENSMUSP00000087073	psi-mi:q99ms3-3(display_long)|uniprotkb:Mpv17l(gene name)|psi-mi:Mpv17l(display_short)|uniprotkb:M-LP short(isoform synonym)	psi-mi:htra2_mouse(display_long)|uniprotkb:Htra2(gene name)|psi-mi:Htra2(display_short)|uniprotkb:Omi(gene name synonym)|uniprotkb:Prss25(gene name synonym)|uniprotkb:High temperature requirement protein A2(gene name synonym)|uniprotkb:Omi stress-regulated endoprotease(gene name synonym)|uniprotkb:Serine proteinase OMI(gene name synonym)|uniprotkb:Serine protease 25(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Krick et al. (2008)	pubmed:18772386|doi:10.1073/pnas.0801146105|imex:IM-9529	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15727112|imex:IM-9529-4|dip:DIP-88227E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000022679(gene)|ensembl:ENSMUST00000124947(transcript)|intact:EBI-15727135(isoform-parent)	refseq:NP_062726.3|dip:DIP-41272N|ensembl:ENSMUSG00000068329(gene)|ensembl:ENSMUST00000089645(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006508"(proteolysis)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0007568"(aging)|go:"GO:0007628"(adult walking behavior)|go:"GO:0008233"(peptidase activity)|go:"GO:0008236"(serine-type peptidase activity)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0009635"(response to herbicide)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010822"(positive regulation of mitochondrion organization)|go:"GO:0012501"(programmed cell death)|go:"GO:0016020"(membrane)|go:"GO:0019742"(pentacyclic triterpenoid metabolic process)|go:"GO:0030900"(forebrain development)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0034605"(cellular response to heat)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035631"(CD40 receptor complex)|go:"GO:0040014"(regulation of multicellular organism growth)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0044257"(cellular protein catabolic process)|go:"GO:0048666"(neuron development)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0097193"(intrinsic apoptotic signaling pathway)|go:"GO:1904924"(negative regulation of mitophagy in response to mitochondrial depolarization)|go:"GO:1905370"(serine-type endopeptidase complex)|go:"GO:2001241"(positive regulation of extrinsic apoptotic signaling pathway in absence of ligand)|go:"GO:2001269"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001940(Peptidase S1C, HrtA/DegP2/Q/S)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR036034|interpro:IPR041489|mint:Q9JIY5	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2017/08/06	2017/08/10	rogid:JS5b+qzBzmiVNZEJDl42PX5aJig10090	rogid:hFFaMR4foetALMvFA0cg4KuxjuE10090	rigid:WF6IT74+VBTrxeIdVePNcQVNeks	false	green fluorescent protein tag:?-?	flag tag:n-n	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q99MS3	uniprotkb:Q9JIY5	intact:EBI-15727135|ensembl:ENSMUSP00000023360|uniprotkb:Q3UWD2|uniprotkb:Q8CI14	intact:EBI-2365838|uniprotkb:Q9R108|ensembl:ENSMUSP00000087073	psi-mi:mp17l_mouse(display_long)|uniprotkb:Mpv17l(gene name)|psi-mi:Mpv17l(display_short)	psi-mi:htra2_mouse(display_long)|uniprotkb:Htra2(gene name)|psi-mi:Htra2(display_short)|uniprotkb:Omi(gene name synonym)|uniprotkb:Prss25(gene name synonym)|uniprotkb:High temperature requirement protein A2(gene name synonym)|uniprotkb:Omi stress-regulated endoprotease(gene name synonym)|uniprotkb:Serine proteinase OMI(gene name synonym)|uniprotkb:Serine protease 25(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Krick et al. (2008)	pubmed:18772386|doi:10.1073/pnas.0801146105|imex:IM-9529	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15727166|imex:IM-9529-5|dip:DIP-88228E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000022679(gene)|ensembl:ENSMUST00000023360(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005777"(peroxisome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0010730"(negative regulation of hydrogen peroxide biosynthetic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:1901029"(negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway)|interpro:IPR007248(Mpv17/PMP22)|refseq:NP_001276491.1|refseq:NP_001276492.1|refseq:NP_001276494.1|refseq:NP_001276496.1|refseq:NP_291042.2|refseq:XP_011244354.1|dip:DIP-46298N	refseq:NP_062726.3|dip:DIP-41272N|ensembl:ENSMUSG00000068329(gene)|ensembl:ENSMUST00000089645(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006508"(proteolysis)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0007568"(aging)|go:"GO:0007628"(adult walking behavior)|go:"GO:0008233"(peptidase activity)|go:"GO:0008236"(serine-type peptidase activity)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0009635"(response to herbicide)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010822"(positive regulation of mitochondrion organization)|go:"GO:0012501"(programmed cell death)|go:"GO:0016020"(membrane)|go:"GO:0019742"(pentacyclic triterpenoid metabolic process)|go:"GO:0030900"(forebrain development)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0034605"(cellular response to heat)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035631"(CD40 receptor complex)|go:"GO:0040014"(regulation of multicellular organism growth)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0044257"(cellular protein catabolic process)|go:"GO:0048666"(neuron development)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0097193"(intrinsic apoptotic signaling pathway)|go:"GO:1904924"(negative regulation of mitophagy in response to mitochondrial depolarization)|go:"GO:1905370"(serine-type endopeptidase complex)|go:"GO:2001241"(positive regulation of extrinsic apoptotic signaling pathway in absence of ligand)|go:"GO:2001269"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001940(Peptidase S1C, HrtA/DegP2/Q/S)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR036034|interpro:IPR041489|mint:Q9JIY5	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse)|taxid:10090(Mus musculus)	-	2017/08/06	2017/08/10	rogid:AeFEN4IFmEjcpNcbSOeqfNKIvHA10090	rogid:hFFaMR4foetALMvFA0cg4KuxjuE10090	rigid:wJ9VglEtCRj5qO+pH7Nk0ev5Y8E	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9JIY5	uniprotkb:Q99MS3-3	intact:EBI-2365838|uniprotkb:Q9R108|ensembl:ENSMUSP00000087073	intact:EBI-15727109|ensembl:ENSMUSP00000117826	psi-mi:htra2_mouse(display_long)|uniprotkb:Htra2(gene name)|psi-mi:Htra2(display_short)|uniprotkb:Omi(gene name synonym)|uniprotkb:Prss25(gene name synonym)|uniprotkb:High temperature requirement protein A2(gene name synonym)|uniprotkb:Omi stress-regulated endoprotease(gene name synonym)|uniprotkb:Serine proteinase OMI(gene name synonym)|uniprotkb:Serine protease 25(gene name synonym)	psi-mi:q99ms3-3(display_long)|uniprotkb:Mpv17l(gene name)|psi-mi:Mpv17l(display_short)|uniprotkb:M-LP short(isoform synonym)	psi-mi:"MI:0096"(pull down)	Krick et al. (2008)	pubmed:18772386|doi:10.1073/pnas.0801146105|imex:IM-9529	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15727183|imex:IM-9529-2|dip:DIP-88227E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_062726.3|dip:DIP-41272N|ensembl:ENSMUSG00000068329(gene)|ensembl:ENSMUST00000089645(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006508"(proteolysis)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0007568"(aging)|go:"GO:0007628"(adult walking behavior)|go:"GO:0008233"(peptidase activity)|go:"GO:0008236"(serine-type peptidase activity)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0009635"(response to herbicide)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010822"(positive regulation of mitochondrion organization)|go:"GO:0012501"(programmed cell death)|go:"GO:0016020"(membrane)|go:"GO:0019742"(pentacyclic triterpenoid metabolic process)|go:"GO:0030900"(forebrain development)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0034605"(cellular response to heat)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035631"(CD40 receptor complex)|go:"GO:0040014"(regulation of multicellular organism growth)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0044257"(cellular protein catabolic process)|go:"GO:0048666"(neuron development)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0097193"(intrinsic apoptotic signaling pathway)|go:"GO:1904924"(negative regulation of mitophagy in response to mitochondrial depolarization)|go:"GO:1905370"(serine-type endopeptidase complex)|go:"GO:2001241"(positive regulation of extrinsic apoptotic signaling pathway in absence of ligand)|go:"GO:2001269"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001940(Peptidase S1C, HrtA/DegP2/Q/S)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR036034|interpro:IPR041489|mint:Q9JIY5	ensembl:ENSMUSG00000022679(gene)|ensembl:ENSMUST00000124947(transcript)|intact:EBI-15727135(isoform-parent)	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/06	2017/08/10	rogid:hFFaMR4foetALMvFA0cg4KuxjuE10090	rogid:JS5b+qzBzmiVNZEJDl42PX5aJig10090	rigid:WF6IT74+VBTrxeIdVePNcQVNeks	false	-	glutathione s tranferase tag:?-?	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q99MS3	uniprotkb:Q9JIY5	intact:EBI-15727135|ensembl:ENSMUSP00000023360|uniprotkb:Q3UWD2|uniprotkb:Q8CI14	intact:EBI-2365838|uniprotkb:Q9R108|ensembl:ENSMUSP00000087073	psi-mi:mp17l_mouse(display_long)|uniprotkb:Mpv17l(gene name)|psi-mi:Mpv17l(display_short)	psi-mi:htra2_mouse(display_long)|uniprotkb:Htra2(gene name)|psi-mi:Htra2(display_short)|uniprotkb:Omi(gene name synonym)|uniprotkb:Prss25(gene name synonym)|uniprotkb:High temperature requirement protein A2(gene name synonym)|uniprotkb:Omi stress-regulated endoprotease(gene name synonym)|uniprotkb:Serine proteinase OMI(gene name synonym)|uniprotkb:Serine protease 25(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Krick et al. (2008)	pubmed:18772386|doi:10.1073/pnas.0801146105|imex:IM-9529	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15727204|imex:IM-9529-6|dip:DIP-88228E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000022679(gene)|ensembl:ENSMUST00000023360(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005777"(peroxisome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0010730"(negative regulation of hydrogen peroxide biosynthetic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:1901029"(negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway)|interpro:IPR007248(Mpv17/PMP22)|refseq:NP_001276491.1|refseq:NP_001276492.1|refseq:NP_001276494.1|refseq:NP_001276496.1|refseq:NP_291042.2|refseq:XP_011244354.1|dip:DIP-46298N	refseq:NP_062726.3|dip:DIP-41272N|ensembl:ENSMUSG00000068329(gene)|ensembl:ENSMUST00000089645(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006508"(proteolysis)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0007568"(aging)|go:"GO:0007628"(adult walking behavior)|go:"GO:0008233"(peptidase activity)|go:"GO:0008236"(serine-type peptidase activity)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0009635"(response to herbicide)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010822"(positive regulation of mitochondrion organization)|go:"GO:0012501"(programmed cell death)|go:"GO:0016020"(membrane)|go:"GO:0019742"(pentacyclic triterpenoid metabolic process)|go:"GO:0030900"(forebrain development)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0034605"(cellular response to heat)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035631"(CD40 receptor complex)|go:"GO:0040014"(regulation of multicellular organism growth)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0044257"(cellular protein catabolic process)|go:"GO:0048666"(neuron development)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0097193"(intrinsic apoptotic signaling pathway)|go:"GO:1904924"(negative regulation of mitophagy in response to mitochondrial depolarization)|go:"GO:1905370"(serine-type endopeptidase complex)|go:"GO:2001241"(positive regulation of extrinsic apoptotic signaling pathway in absence of ligand)|go:"GO:2001269"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001940(Peptidase S1C, HrtA/DegP2/Q/S)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR036034|interpro:IPR041489|mint:Q9JIY5	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse)|taxid:10090(Mus musculus)	-	2017/08/06	2017/08/10	rogid:AeFEN4IFmEjcpNcbSOeqfNKIvHA10090	rogid:hFFaMR4foetALMvFA0cg4KuxjuE10090	rigid:wJ9VglEtCRj5qO+pH7Nk0ev5Y8E	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9JIY5	uniprotkb:Q99MS3-1	intact:EBI-2365838|uniprotkb:Q9R108|ensembl:ENSMUSP00000087073	intact:EBI-15727082|ensembl:ENSMUSP00000023360	psi-mi:htra2_mouse(display_long)|uniprotkb:Htra2(gene name)|psi-mi:Htra2(display_short)|uniprotkb:Omi(gene name synonym)|uniprotkb:Prss25(gene name synonym)|uniprotkb:High temperature requirement protein A2(gene name synonym)|uniprotkb:Omi stress-regulated endoprotease(gene name synonym)|uniprotkb:Serine proteinase OMI(gene name synonym)|uniprotkb:Serine protease 25(gene name synonym)	psi-mi:q99ms3-1(display_long)|uniprotkb:Mpv17l(gene name)|psi-mi:Mpv17l(display_short)|uniprotkb:M-LP long(isoform synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Krick et al. (2008)	pubmed:18772386|doi:10.1073/pnas.0801146105|imex:IM-9529	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15727221|imex:IM-9529-3|dip:DIP-88226E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_062726.3|dip:DIP-41272N|ensembl:ENSMUSG00000068329(gene)|ensembl:ENSMUST00000089645(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006508"(proteolysis)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0007568"(aging)|go:"GO:0007628"(adult walking behavior)|go:"GO:0008233"(peptidase activity)|go:"GO:0008236"(serine-type peptidase activity)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0009635"(response to herbicide)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010822"(positive regulation of mitochondrion organization)|go:"GO:0012501"(programmed cell death)|go:"GO:0016020"(membrane)|go:"GO:0019742"(pentacyclic triterpenoid metabolic process)|go:"GO:0030900"(forebrain development)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0034605"(cellular response to heat)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035631"(CD40 receptor complex)|go:"GO:0040014"(regulation of multicellular organism growth)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0044257"(cellular protein catabolic process)|go:"GO:0048666"(neuron development)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0097193"(intrinsic apoptotic signaling pathway)|go:"GO:1904924"(negative regulation of mitophagy in response to mitochondrial depolarization)|go:"GO:1905370"(serine-type endopeptidase complex)|go:"GO:2001241"(positive regulation of extrinsic apoptotic signaling pathway in absence of ligand)|go:"GO:2001269"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001940(Peptidase S1C, HrtA/DegP2/Q/S)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR036034|interpro:IPR041489|mint:Q9JIY5	ensembl:ENSMUSG00000022679(gene)|ensembl:ENSMUST00000023360(transcript)|intact:EBI-15727135(isoform-parent)	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2017/08/06	2017/08/10	rogid:hFFaMR4foetALMvFA0cg4KuxjuE10090	rogid:AeFEN4IFmEjcpNcbSOeqfNKIvHA10090	rigid:wJ9VglEtCRj5qO+pH7Nk0ev5Y8E	false	green fluorescent protein tag:n-n	mutation decreasing interaction:114-114,112-112|flag tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q99MS3-1	uniprotkb:Q9JIY5	intact:EBI-15727082|ensembl:ENSMUSP00000023360	intact:EBI-2365838|uniprotkb:Q9R108|ensembl:ENSMUSP00000087073	psi-mi:q99ms3-1(display_long)|uniprotkb:Mpv17l(gene name)|psi-mi:Mpv17l(display_short)|uniprotkb:M-LP long(isoform synonym)	psi-mi:htra2_mouse(display_long)|uniprotkb:Htra2(gene name)|psi-mi:Htra2(display_short)|uniprotkb:Omi(gene name synonym)|uniprotkb:Prss25(gene name synonym)|uniprotkb:High temperature requirement protein A2(gene name synonym)|uniprotkb:Omi stress-regulated endoprotease(gene name synonym)|uniprotkb:Serine proteinase OMI(gene name synonym)|uniprotkb:Serine protease 25(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Krick et al. (2008)	pubmed:18772386|doi:10.1073/pnas.0801146105|imex:IM-9529	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15727248|imex:IM-9529-7|dip:DIP-88226E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000022679(gene)|ensembl:ENSMUST00000023360(transcript)|intact:EBI-15727135(isoform-parent)	refseq:NP_062726.3|dip:DIP-41272N|ensembl:ENSMUSG00000068329(gene)|ensembl:ENSMUST00000089645(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006508"(proteolysis)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0007568"(aging)|go:"GO:0007628"(adult walking behavior)|go:"GO:0008233"(peptidase activity)|go:"GO:0008236"(serine-type peptidase activity)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0009635"(response to herbicide)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010822"(positive regulation of mitochondrion organization)|go:"GO:0012501"(programmed cell death)|go:"GO:0016020"(membrane)|go:"GO:0019742"(pentacyclic triterpenoid metabolic process)|go:"GO:0030900"(forebrain development)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0034605"(cellular response to heat)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035631"(CD40 receptor complex)|go:"GO:0040014"(regulation of multicellular organism growth)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0044257"(cellular protein catabolic process)|go:"GO:0048666"(neuron development)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0097193"(intrinsic apoptotic signaling pathway)|go:"GO:1904924"(negative regulation of mitophagy in response to mitochondrial depolarization)|go:"GO:1905370"(serine-type endopeptidase complex)|go:"GO:2001241"(positive regulation of extrinsic apoptotic signaling pathway in absence of ligand)|go:"GO:2001269"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001940(Peptidase S1C, HrtA/DegP2/Q/S)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR036034|interpro:IPR041489|mint:Q9JIY5	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2017/08/06	2017/08/10	rogid:AeFEN4IFmEjcpNcbSOeqfNKIvHA10090	rogid:hFFaMR4foetALMvFA0cg4KuxjuE10090	rigid:wJ9VglEtCRj5qO+pH7Nk0ev5Y8E	false	green fluorescent protein tag:?-?	flag tag:n-n	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)