#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:O60603	uniprotkb:P61073	intact:EBI-973722|ensembl:ENSP00000260010|ensembl:ENSP00000494425|ensembl:ENSP00000495339|uniprotkb:O15454|uniprotkb:Q8NI00|uniprotkb:B3Y612|uniprotkb:D1CS45|uniprotkb:D1CS48|uniprotkb:D1CS49	intact:EBI-489411|uniprotkb:Q53S69|uniprotkb:O60835|uniprotkb:P30991|uniprotkb:P56438|uniprotkb:Q9UKN2|uniprotkb:B2R5N0|uniprotkb:Q9BXA0|ensembl:ENSP00000241393	psi-mi:tlr2_human(display_long)|uniprotkb:Toll/interleukin-1 receptor-like protein 4(gene name synonym)|uniprotkb:TLR2(gene name)|psi-mi:TLR2(display_short)|uniprotkb:TIL4(gene name synonym)	psi-mi:cxcr4_human(display_long)|uniprotkb:Stromal cell-derived factor 1 receptor(gene name synonym)|uniprotkb:Fusin(gene name synonym)|uniprotkb:Leukocyte-derived seven transmembrane domain receptor(gene name synonym)|uniprotkb:LCR1(gene name synonym)|uniprotkb:FB22(gene name synonym)|uniprotkb:NPYRL(gene name synonym)|uniprotkb:HM89(gene name synonym)|uniprotkb:CXCR4(gene name)|psi-mi:CXCR4(display_short)|uniprotkb:Lipopolysaccharide-associated protein 3(gene name synonym)	psi-mi:"MI:0055"(fluorescent resonance energy transfer)	Hajishengallis et al. (2008)	pubmed:18765807|doi:10.1073/pnas.0803852105|imex:IM-9524	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15726764|imex:IM-9524-1|dip:DIP-88219E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0583"(fluorescence donor)	psi-mi:"MI:0584"(fluorescence acceptor)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000137462(gene)|ensembl:ENST00000260010(transcript)|ensembl:ENST00000642580(transcript)|ensembl:ENST00000642700(transcript)|go:"GO:0001530"(lipopolysaccharide binding)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001774"(microglial cell activation)|go:"GO:0001775"(cell activation)|go:"GO:0001875"(lipopolysaccharide immune receptor activity)|go:"GO:0002224"(toll-like receptor signaling pathway)|go:"GO:0002755"(MyD88-dependent toll-like receptor signaling pathway)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006691"(leukotriene metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0006955"(immune response)|go:"GO:0007165"(signal transduction)|go:"GO:0007252"(I-kappaB phosphorylation)|go:"GO:0007612"(learning)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009636"(response to toxic substance)|go:"GO:0009986"(cell surface)|go:"GO:0014005"(microglia development)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0031226"(intrinsic component of plasma membrane)|go:"GO:0032289"(central nervous system myelin formation)|go:"GO:0032570"(response to progesterone)|go:"GO:0032722"(positive regulation of chemokine production)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0032733"(positive regulation of interleukin-10 production)|go:"GO:0032735"(positive regulation of interleukin-12 production)|go:"GO:0032741"(positive regulation of interleukin-18 production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032868"(response to insulin)|go:"GO:0034123"(positive regulation of toll-like receptor signaling pathway)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0034134"(toll-like receptor 2 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0035354"(Toll-like receptor 1-Toll-like receptor 2 protein complex)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0038187"(pattern recognition receptor activity)|go:"GO:0042495"(detection of triacyl bacterial lipopeptide)|go:"GO:0042496"(detection of diacyl bacterial lipopeptide)|go:"GO:0042497"(triacyl lipopeptide binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042834"(peptidoglycan binding)|go:"GO:0042995"(cell projection)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045121"(membrane raft)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046209"(nitric oxide metabolic process)|go:"GO:0048714"(positive regulation of oligodendrocyte differentiation)|go:"GO:0050135"("NAD(P)+ nucleosidase activity")|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0050765"(negative regulation of phagocytosis)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051607"(defense response to virus)|go:"GO:0051770"(positive regulation of nitric-oxide synthase biosynthetic process)|go:"GO:0051964"(negative regulation of synapse assembly)|go:"GO:0061809"(NAD+ nucleotidase, cyclic ADP-ribose generating)|go:"GO:0070542"(response to fatty acid)|go:"GO:0071221"(cellular response to bacterial lipopeptide)|go:"GO:0071223"(cellular response to lipoteichoic acid)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0071726"(cellular response to diacyl bacterial lipopeptide)|go:"GO:0071727"(cellular response to triacyl bacterial lipopeptide)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1903974"(positive regulation of cellular response to macrophage colony-stimulating factor stimulus)|go:"GO:1904466"(positive regulation of matrix metallopeptidase secretion)|interpro:IPR000157(Toll-Interleukin receptor)|interpro:IPR000483(Cysteine-rich flanking region, C-terminal)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR017241(Toll-like receptor)|interpro:IPR027185|interpro:IPR032675|interpro:IPR035897|mint:O60603|rcsb pdb:1FYW|rcsb pdb:1FYX|rcsb pdb:1O77|rcsb pdb:2Z7X|rcsb pdb:2Z80|rcsb pdb:6NIG|reactome:R-HSA-1461957|reactome:R-HSA-166058|reactome:R-HSA-168179|reactome:R-HSA-168188|reactome:R-HSA-5602498|reactome:R-HSA-5603041|reactome:R-HSA-5686938|reactome:R-HSA-6798695|reactome:R-HSA-9637628|reactome:R-HSA-1236974|refseq:NP_003255.2|refseq:XP_011530517.1|refseq:XP_011530518.1|refseq:XP_016864062.1|refseq:XP_016864063.1|refseq:XP_016864064.1|refseq:XP_016864065.1|refseq:NP_001305716.1|refseq:NP_001305718.1|refseq:NP_001305719.1|refseq:NP_001305720.1|refseq:NP_001305722.1|refseq:NP_001305725.1|refseq:NP_001305724.1|dip:DIP-35138N	refseq:NP_001008540.1|refseq:NP_003458.1|refseq:NP_001334985.1|refseq:NP_001334988.1|refseq:NP_001334989.1|dip:DIP-34773N|dip:DIP-46290N|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0006955"(immune response)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007420"(brain development)|go:"GO:0008038"(neuron recognition)|go:"GO:0009615"(response to virus)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0014823"(response to activity)|go:"GO:0015026"(coreceptor activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016493"(C-C chemokine receptor activity)|go:"GO:0016494"(C-X-C chemokine receptor activity)|go:"GO:0019722"(calcium-mediated signaling)|go:"GO:0019957"(C-C chemokine binding)|go:"GO:0022008"(neurogenesis)|go:"GO:0022029"(telencephalon cell migration)|go:"GO:0030054"(cell junction)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0031252"(cell leading edge)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032027"(myosin light chain binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035470"(positive regulation of vascular wound healing)|go:"GO:0035690"|go:"GO:0038147"(C-X-C motif chemokine 12 receptor activity)|go:"GO:0038160"(CXCL12-activated CXCR4 signaling pathway)|go:"GO:0043067"(regulation of programmed cell death)|go:"GO:0043130"(ubiquitin binding)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|interpro:IPR022726|mint:P61073|rcsb pdb:2K03|rcsb pdb:2K04|rcsb pdb:2K05|rcsb pdb:2N55|rcsb pdb:3ODU|rcsb pdb:3OE0|rcsb pdb:3OE6|rcsb pdb:3OE8|rcsb pdb:3OE9|rcsb pdb:4RWS|reactome:R-HSA-173107|reactome:R-HSA-376176|reactome:R-HSA-380108|reactome:R-HSA-418594|go:"GO:0043217"(myelin maintenance)|go:"GO:0043278"(response to morphine)|go:"GO:0045446"(endothelial cell differentiation)|go:"GO:0048714"(positive regulation of oligodendrocyte differentiation)|go:"GO:0050792"(regulation of viral process)|go:"GO:0050920"(regulation of chemotaxis)|go:"GO:0050921"(positive regulation of chemotaxis)|go:"GO:0050965"(detection of temperature stimulus involved in sensory perception of pain)|go:"GO:0050966"(detection of mechanical stimulus involved in sensory perception of pain)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0061154"(endothelial tube morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:1903861"(positive regulation of dendrite extension)|go:"GO:1905322"(positive regulation of mesenchymal stem cell migration)|go:"GO:1990478"(response to ultrasound)|go:"GO:2000448"(positive regulation of macrophage migration inhibitory factor signaling pathway)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR000355(Chemokine receptor)|interpro:IPR001277(C-X-C chemokine receptor, type 4)|ensembl:ENSG00000121966(gene)|ensembl:ENST00000241393(transcript)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0001618"(virus receptor activity)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001764"(neuron migration)|go:"GO:0002064"(epithelial cell development)|go:"GO:0002407"(dendritic cell chemotaxis)|go:"GO:0003779"(actin binding)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2017/08/06	2017/08/10	rogid:6xdppMwVYR7qWpDocSsqwvocdU89606	rogid:/DC0/+M1YsFLLfsDimppXSS/vpQ9606	rigid:Js9G8SQnfr/5PSFZlSvGQm/cjuY	false	cy3 label:?-?	cy5 label:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P08571	uniprotkb:O60603	intact:EBI-3905196|uniprotkb:Q96L99|uniprotkb:Q53XT5|uniprotkb:Q9UNS3|uniprotkb:Q96FR6|ensembl:ENSP00000304236|ensembl:ENSP00000385519	intact:EBI-973722|ensembl:ENSP00000260010|ensembl:ENSP00000494425|ensembl:ENSP00000495339|uniprotkb:O15454|uniprotkb:Q8NI00|uniprotkb:B3Y612|uniprotkb:D1CS45|uniprotkb:D1CS48|uniprotkb:D1CS49	psi-mi:cd14_human(display_long)|uniprotkb:CD14(gene name)|psi-mi:CD14(display_short)|uniprotkb:Myeloid cell-specific leucine-rich glycoprotein(gene name synonym)	psi-mi:tlr2_human(display_long)|uniprotkb:Toll/interleukin-1 receptor-like protein 4(gene name synonym)|uniprotkb:TLR2(gene name)|psi-mi:TLR2(display_short)|uniprotkb:TIL4(gene name synonym)	psi-mi:"MI:0055"(fluorescent resonance energy transfer)	Hajishengallis et al. (2008)	pubmed:18765807|doi:10.1073/pnas.0803852105|imex:IM-9524	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15726785|imex:IM-9524-2|dip:DIP-88220E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0584"(fluorescence acceptor)	psi-mi:"MI:0583"(fluorescence donor)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000582.1|refseq:NP_001035110.1|refseq:NP_001167575.1|refseq:NP_001167576.1|dip:DIP-1030N|ensembl:ENSG00000170458(gene)|ensembl:ENST00000302014(transcript)|ensembl:ENST00000401743(transcript)|go:"GO:0001530"(lipopolysaccharide binding)|go:"GO:0001847"(opsonin receptor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0006909"(phagocytosis)|go:"GO:0006915"(apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0009408"(response to heat)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0016019"(peptidoglycan immune receptor activity)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0031362"(anchored component of external side of plasma membrane)|go:"GO:0031663"(lipopolysaccharide-mediated signaling pathway)|go:"GO:0032026"(response to magnesium ion)|go:"GO:0032481"(positive regulation of type I interferon production)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0034142"(toll-like receptor 4 signaling pathway)|go:"GO:0034612"(response to tumor necrosis factor)|go:"GO:0045087"(innate immune response)|go:"GO:0045121"(membrane raft)|go:"GO:0045471"(response to ethanol)|go:"GO:0045807"(positive regulation of endocytosis)|go:"GO:0046696"(lipopolysaccharide receptor complex)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070891"(lipoteichoic acid binding)|go:"GO:0071219"(cellular response to molecule of bacterial origin)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071223"(cellular response to lipoteichoic acid)|go:"GO:0071723"(lipopeptide binding)|go:"GO:0071726"(cellular response to diacyl bacterial lipopeptide)|go:"GO:0071727"(cellular response to triacyl bacterial lipopeptide)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR016337(Monocyte differentiation antigen CD14)|interpro:IPR032675|rcsb pdb:4GLP|reactome:R-HSA-1236974|reactome:R-HSA-140534|reactome:R-HSA-166016|reactome:R-HSA-166020|reactome:R-HSA-166058|reactome:R-HSA-166166|reactome:R-HSA-168179|reactome:R-HSA-168188|reactome:R-HSA-2562578|reactome:R-HSA-5602498|reactome:R-HSA-5603041|reactome:R-HSA-5686938|reactome:R-HSA-6798695|reactome:R-HSA-936964|reactome:R-HSA-937041|reactome:R-HSA-937072|reactome:R-HSA-975163|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)	ensembl:ENSG00000137462(gene)|ensembl:ENST00000260010(transcript)|ensembl:ENST00000642580(transcript)|ensembl:ENST00000642700(transcript)|go:"GO:0001530"(lipopolysaccharide binding)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001774"(microglial cell activation)|go:"GO:0001775"(cell activation)|go:"GO:0001875"(lipopolysaccharide immune receptor activity)|go:"GO:0002224"(toll-like receptor signaling pathway)|go:"GO:0002755"(MyD88-dependent toll-like receptor signaling pathway)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006691"(leukotriene metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0006955"(immune response)|go:"GO:0007165"(signal transduction)|go:"GO:0007252"(I-kappaB phosphorylation)|go:"GO:0007612"(learning)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009636"(response to toxic substance)|go:"GO:0009986"(cell surface)|go:"GO:0014005"(microglia development)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0031226"(intrinsic component of plasma membrane)|go:"GO:0032289"(central nervous system myelin formation)|go:"GO:0032570"(response to progesterone)|go:"GO:0032722"(positive regulation of chemokine production)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0032733"(positive regulation of interleukin-10 production)|go:"GO:0032735"(positive regulation of interleukin-12 production)|go:"GO:0032741"(positive regulation of interleukin-18 production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032868"(response to insulin)|go:"GO:0034123"(positive regulation of toll-like receptor signaling pathway)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0034134"(toll-like receptor 2 signaling pathway)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0035354"(Toll-like receptor 1-Toll-like receptor 2 protein complex)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0038187"(pattern recognition receptor activity)|go:"GO:0042495"(detection of triacyl bacterial lipopeptide)|go:"GO:0042496"(detection of diacyl bacterial lipopeptide)|go:"GO:0042497"(triacyl lipopeptide binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042834"(peptidoglycan binding)|go:"GO:0042995"(cell projection)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045121"(membrane raft)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046209"(nitric oxide metabolic process)|go:"GO:0048714"(positive regulation of oligodendrocyte differentiation)|go:"GO:0050135"("NAD(P)+ nucleosidase activity")|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0050765"(negative regulation of phagocytosis)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051607"(defense response to virus)|go:"GO:0051770"(positive regulation of nitric-oxide synthase biosynthetic process)|go:"GO:0051964"(negative regulation of synapse assembly)|go:"GO:0061809"(NAD+ nucleotidase, cyclic ADP-ribose generating)|go:"GO:0070542"(response to fatty acid)|go:"GO:0071221"(cellular response to bacterial lipopeptide)|go:"GO:0071223"(cellular response to lipoteichoic acid)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0071726"(cellular response to diacyl bacterial lipopeptide)|go:"GO:0071727"(cellular response to triacyl bacterial lipopeptide)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1903974"(positive regulation of cellular response to macrophage colony-stimulating factor stimulus)|go:"GO:1904466"(positive regulation of matrix metallopeptidase secretion)|interpro:IPR000157(Toll-Interleukin receptor)|interpro:IPR000483(Cysteine-rich flanking region, C-terminal)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR017241(Toll-like receptor)|interpro:IPR027185|interpro:IPR032675|interpro:IPR035897|mint:O60603|rcsb pdb:1FYW|rcsb pdb:1FYX|rcsb pdb:1O77|rcsb pdb:2Z7X|rcsb pdb:2Z80|rcsb pdb:6NIG|reactome:R-HSA-1461957|reactome:R-HSA-166058|reactome:R-HSA-168179|reactome:R-HSA-168188|reactome:R-HSA-5602498|reactome:R-HSA-5603041|reactome:R-HSA-5686938|reactome:R-HSA-6798695|reactome:R-HSA-9637628|reactome:R-HSA-1236974|refseq:NP_003255.2|refseq:XP_011530517.1|refseq:XP_011530518.1|refseq:XP_016864062.1|refseq:XP_016864063.1|refseq:XP_016864064.1|refseq:XP_016864065.1|refseq:NP_001305716.1|refseq:NP_001305718.1|refseq:NP_001305719.1|refseq:NP_001305720.1|refseq:NP_001305722.1|refseq:NP_001305725.1|refseq:NP_001305724.1|dip:DIP-35138N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2017/08/06	2017/08/10	rogid:MpfQfOF+t0EMlzBio2kyYeJU3hE9606	rogid:6xdppMwVYR7qWpDocSsqwvocdU89606	rigid:blAKYJPca9raZhH9Vp/vtqNdyow	false	cy5 label:?-?	cy3 label:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)