#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q969F2 intact:EBI-4399559 intact:EBI-1538629|uniprotkb:Q96EK8|uniprotkb:Q9BSN0|ensembl:ENSP00000296849|ensembl:ENSP00000479003 dip:DIP-24261N psi-mi:nkd2_human(display_long)|uniprotkb:NKD2(gene name)|psi-mi:NKD2(display_short) psi-mi:ubiq_human(display_short)|psi-mi:EBI-4399559(display_long) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Ding et al. (2008) pubmed:18757723|doi:10.1073/pnas.0806298105|imex:IM-14305 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15726312|imex:IM-14305-1|dip:DIP-103160E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_149111.1|refseq:NP_001258011.1|ensembl:ENST00000274150|ensembl:ENSP00000274150|ensembl:ENSP00000296849|ensembl:ENST00000610777|ensembl:ENSP00000482896|ensembl:ENSP00000479003|dip:DIP-38642N|ensembl:ENSG00000145506(gene)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019838"(growth factor binding)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032036"(myosin heavy chain binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0048210"(Golgi vesicle fusion to target membrane)|ensembl:ENSG00000276920(gene)|ensembl:ENST00000296849(transcript)|ensembl:ENST00000616539(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006887"(exocytosis)|go:"GO:0010954"(positive regulation of protein processing)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0051117"(ATPase binding)|go:"GO:0070382"(exocytic vesicle)|go:"GO:0071944"(cell periphery)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR040140|mint:Q969F2 uniprotkb:UBIQ_HUMAN(see-also)|refseq:NP_066289.2 psi-mi:"MI:0465"(dip) - no-uniprot-update: full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/06 2017/08/15 rogid:kQxbG3sbnbXPkaywAkvN6ip1+Bw9606 rogid:dobaeYpohKyDSnm4fBbcy0ZbYwM9606 rigid:xJqquO9NsLom6p8zJOMmPlz8K5w false - ha tag:0-0 - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q969F2 uniprotkb:Q96BH1 intact:EBI-1538629|uniprotkb:Q96EK8|uniprotkb:Q9BSN0|ensembl:ENSP00000296849|ensembl:ENSP00000479003 intact:EBI-2129220|uniprotkb:A8K0D6|uniprotkb:Q9H874|uniprotkb:Q53HQ5|ensembl:ENSP00000295704 psi-mi:nkd2_human(display_long)|uniprotkb:NKD2(gene name)|psi-mi:NKD2(display_short) psi-mi:rnf25_human(display_long)|uniprotkb:RNF25(gene name)|psi-mi:RNF25(display_short)|uniprotkb:RING finger protein 25(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RNF25(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ding et al. (2008) pubmed:18757723|doi:10.1073/pnas.0806298105|imex:IM-14305 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15726331|imex:IM-14305-2|dip:DIP-103161E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_149111.1|refseq:NP_001258011.1|ensembl:ENST00000274150|ensembl:ENSP00000274150|ensembl:ENSP00000296849|ensembl:ENST00000610777|ensembl:ENSP00000482896|ensembl:ENSP00000479003|dip:DIP-38642N|ensembl:ENSG00000145506(gene)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019838"(growth factor binding)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032036"(myosin heavy chain binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0048210"(Golgi vesicle fusion to target membrane)|ensembl:ENSG00000276920(gene)|ensembl:ENST00000296849(transcript)|ensembl:ENST00000616539(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006887"(exocytosis)|go:"GO:0010954"(positive regulation of protein processing)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0051117"(ATPase binding)|go:"GO:0070382"(exocytic vesicle)|go:"GO:0071944"(cell periphery)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR040140|mint:Q969F2 refseq:NP_071898.2|dip:DIP-29063N|ensembl:ENSG00000163481(gene)|ensembl:ENST00000295704(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR006575(RWD)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR039133|rcsb pdb:2DAY|rcsb pdb:2DMF|rcsb pdb:5D1K|rcsb pdb:5D1L|rcsb pdb:5D1M|reactome:R-HSA-983168 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/06 2017/08/10 rogid:kQxbG3sbnbXPkaywAkvN6ip1+Bw9606 rogid:YyCN7mH4eng9G05zRci49oJzKO09606 rigid:rTWLutsXialKrMAroOz6MfhaTJ0 false green fluorescent protein tag:c-c ha tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q969F2 intact:EBI-4399559 intact:EBI-1538629|uniprotkb:Q96EK8|uniprotkb:Q9BSN0|ensembl:ENSP00000296849|ensembl:ENSP00000479003 dip:DIP-24261N psi-mi:nkd2_human(display_long)|uniprotkb:NKD2(gene name)|psi-mi:NKD2(display_short) psi-mi:ubiq_human(display_short)|psi-mi:EBI-4399559(display_long) psi-mi:"MI:0808"(comigration in sds page) Ding et al. (2008) pubmed:18757723|doi:10.1073/pnas.0806298105|imex:IM-14305 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0195"(covalent binding) psi-mi:"MI:0465"(DIP) intact:EBI-15726352|imex:IM-14305-3|dip:DIP-103160E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_149111.1|refseq:NP_001258011.1|ensembl:ENST00000274150|ensembl:ENSP00000274150|ensembl:ENSP00000296849|ensembl:ENST00000610777|ensembl:ENSP00000482896|ensembl:ENSP00000479003|dip:DIP-38642N|ensembl:ENSG00000145506(gene)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019838"(growth factor binding)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032036"(myosin heavy chain binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0048210"(Golgi vesicle fusion to target membrane)|ensembl:ENSG00000276920(gene)|ensembl:ENST00000296849(transcript)|ensembl:ENST00000616539(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006887"(exocytosis)|go:"GO:0010954"(positive regulation of protein processing)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0051117"(ATPase binding)|go:"GO:0070382"(exocytic vesicle)|go:"GO:0071944"(cell periphery)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR040140|mint:Q969F2 uniprotkb:UBIQ_HUMAN(see-also)|refseq:NP_066289.2 psi-mi:"MI:0465"(dip) - no-uniprot-update: full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/06 2017/08/15 rogid:kQxbG3sbnbXPkaywAkvN6ip1+Bw9606 rogid:dobaeYpohKyDSnm4fBbcy0ZbYwM9606 rigid:xJqquO9NsLom6p8zJOMmPlz8K5w false green fluorescent protein tag:c-c ha tag:0-0 - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q969F2 uniprotkb:P01135 intact:EBI-1538629|uniprotkb:Q96EK8|uniprotkb:Q9BSN0|ensembl:ENSP00000296849|ensembl:ENSP00000479003 intact:EBI-1034374|uniprotkb:Q15577|uniprotkb:A8K286|uniprotkb:Q53SK7|uniprotkb:Q9BS56|uniprotkb:Q9UEI3|uniprotkb:Q9UKM1|uniprotkb:Q9UKM2|ensembl:ENSP00000295400|uniprotkb:Q9UKM3 psi-mi:nkd2_human(display_long)|uniprotkb:NKD2(gene name)|psi-mi:NKD2(display_short) psi-mi:tgfa_human(display_long)|uniprotkb:TGFA(gene name)|psi-mi:TGFA(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ding et al. (2008) pubmed:18757723|doi:10.1073/pnas.0806298105|imex:IM-14305 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15726373|imex:IM-14305-4|dip:DIP-66678E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_149111.1|refseq:NP_001258011.1|ensembl:ENST00000274150|ensembl:ENSP00000274150|ensembl:ENSP00000296849|ensembl:ENST00000610777|ensembl:ENSP00000482896|ensembl:ENSP00000479003|dip:DIP-38642N|ensembl:ENSG00000145506(gene)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019838"(growth factor binding)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032036"(myosin heavy chain binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0048210"(Golgi vesicle fusion to target membrane)|ensembl:ENSG00000276920(gene)|ensembl:ENST00000296849(transcript)|ensembl:ENST00000616539(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006887"(exocytosis)|go:"GO:0010954"(positive regulation of protein processing)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0051117"(ATPase binding)|go:"GO:0070382"(exocytic vesicle)|go:"GO:0071944"(cell periphery)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR040140|mint:Q969F2 refseq:NP_001093161.1|refseq:NP_003227.1|ensembl:ENSG00000163235(gene)|ensembl:ENST00000295400(transcript)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0001525"(angiogenesis)|go:"GO:0005154"(epidermal growth factor receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0008083"(growth factor activity)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042060"(wound healing)|go:"GO:0042493"|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0045741"(positive regulation of epidermal growth factor-activated receptor activity)|go:"GO:0045840"(positive regulation of mitotic nuclear division)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0051781"(positive regulation of cell division)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0072574"(hepatocyte proliferation)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR015497(Epidermal growth factor receptor ligand)|mint:P01135|rcsb pdb:1GK5|rcsb pdb:1MOX|rcsb pdb:1YUF|rcsb pdb:1YUG|rcsb pdb:2TGF|rcsb pdb:3E50|rcsb pdb:3TGF|rcsb pdb:4TGF|rcsb pdb:5KN5|reactome:R-HSA-1257604|reactome:R-HSA-177929|reactome:R-HSA-179812|reactome:R-HSA-180292|reactome:R-HSA-180336|reactome:R-HSA-182971|reactome:R-HSA-204005|reactome:R-HSA-212718|reactome:R-HSA-2219530|reactome:R-HSA-5638303|reactome:R-HSA-5673001|reactome:R-HSA-5694530|reactome:R-HSA-6811558|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8866910|reactome:R-HSA-9009391|reactome:R-HSA-9018519|reactome:R-HSA-9634638|refseq:NP_001295087.1|refseq:NP_001295088.1|dip:DIP-5765N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/06 2017/08/10 rogid:kQxbG3sbnbXPkaywAkvN6ip1+Bw9606 rogid:mlXfKDlrB4yc75KnlxjdqCEegYs9606 rigid:Eu07cuwjMsbrMyT8YWYH9JPpEmc false - experimental feature:n-n - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q969F2 uniprotkb:Q96BH1 intact:EBI-1538629|uniprotkb:Q96EK8|uniprotkb:Q9BSN0|ensembl:ENSP00000296849|ensembl:ENSP00000479003 intact:EBI-2129220|uniprotkb:A8K0D6|uniprotkb:Q9H874|uniprotkb:Q53HQ5|ensembl:ENSP00000295704 psi-mi:nkd2_human(display_long)|uniprotkb:NKD2(gene name)|psi-mi:NKD2(display_short) psi-mi:rnf25_human(display_long)|uniprotkb:RNF25(gene name)|psi-mi:RNF25(display_short)|uniprotkb:RING finger protein 25(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RNF25(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Ding et al. (2008) pubmed:18757723|doi:10.1073/pnas.0806298105|imex:IM-14305 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15726392|imex:IM-14305-5|dip:DIP-103161E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_149111.1|refseq:NP_001258011.1|ensembl:ENST00000274150|ensembl:ENSP00000274150|ensembl:ENSP00000296849|ensembl:ENST00000610777|ensembl:ENSP00000482896|ensembl:ENSP00000479003|dip:DIP-38642N|ensembl:ENSG00000145506(gene)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019838"(growth factor binding)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032036"(myosin heavy chain binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0048210"(Golgi vesicle fusion to target membrane)|ensembl:ENSG00000276920(gene)|ensembl:ENST00000296849(transcript)|ensembl:ENST00000616539(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006887"(exocytosis)|go:"GO:0010954"(positive regulation of protein processing)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0051117"(ATPase binding)|go:"GO:0070382"(exocytic vesicle)|go:"GO:0071944"(cell periphery)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR040140|mint:Q969F2 refseq:NP_071898.2|dip:DIP-29063N|ensembl:ENSG00000163481(gene)|ensembl:ENST00000295704(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR006575(RWD)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR039133|rcsb pdb:2DAY|rcsb pdb:2DMF|rcsb pdb:5D1K|rcsb pdb:5D1L|rcsb pdb:5D1M|reactome:R-HSA-983168 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/06 2017/08/10 rogid:kQxbG3sbnbXPkaywAkvN6ip1+Bw9606 rogid:YyCN7mH4eng9G05zRci49oJzKO09606 rigid:rTWLutsXialKrMAroOz6MfhaTJ0 false - ha tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q969F2 intact:EBI-4399559 intact:EBI-1538629|uniprotkb:Q96EK8|uniprotkb:Q9BSN0|ensembl:ENSP00000296849|ensembl:ENSP00000479003 dip:DIP-24261N psi-mi:nkd2_human(display_long)|uniprotkb:NKD2(gene name)|psi-mi:NKD2(display_short) psi-mi:ubiq_human(display_short)|psi-mi:EBI-4399559(display_long) psi-mi:"MI:0808"(comigration in sds page) Ding et al. (2008) pubmed:18757723|doi:10.1073/pnas.0806298105|imex:IM-14305 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0195"(covalent binding) psi-mi:"MI:0465"(DIP) intact:EBI-15726411|imex:IM-14305-6|dip:DIP-103160E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_149111.1|refseq:NP_001258011.1|ensembl:ENST00000274150|ensembl:ENSP00000274150|ensembl:ENSP00000296849|ensembl:ENST00000610777|ensembl:ENSP00000482896|ensembl:ENSP00000479003|dip:DIP-38642N|ensembl:ENSG00000145506(gene)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019838"(growth factor binding)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032036"(myosin heavy chain binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0048210"(Golgi vesicle fusion to target membrane)|ensembl:ENSG00000276920(gene)|ensembl:ENST00000296849(transcript)|ensembl:ENST00000616539(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006887"(exocytosis)|go:"GO:0010954"(positive regulation of protein processing)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0051117"(ATPase binding)|go:"GO:0070382"(exocytic vesicle)|go:"GO:0071944"(cell periphery)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR040140|mint:Q969F2 uniprotkb:UBIQ_HUMAN(see-also)|refseq:NP_066289.2 psi-mi:"MI:0465"(dip) - no-uniprot-update: full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/06 2017/08/15 rogid:kQxbG3sbnbXPkaywAkvN6ip1+Bw9606 rogid:dobaeYpohKyDSnm4fBbcy0ZbYwM9606 rigid:xJqquO9NsLom6p8zJOMmPlz8K5w false - ha tag:0-0 - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot)