#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P53894	uniprotkb:P21192	intact:EBI-4110|uniprotkb:D6W122|ensemblfungi:YNL161W	intact:EBI-2073|uniprotkb:D6VYC6|ensemblfungi:YLR131C	psi-mi:cbk1_yeast(display_long)|uniprotkb:CBK1(gene name)|psi-mi:CBK1(display_short)|uniprotkb:YNL161W(locus name)|uniprotkb:N1727(orf name)|uniprotkb:Cell wall biosynthesis kinase(gene name synonym)	psi-mi:ace2_yeast(display_long)|uniprotkb:ACE2(gene name)|psi-mi:ACE2(display_short)|uniprotkb:L3123(orf name)|uniprotkb:L9606.10(orf name)|uniprotkb:YLR131C(locus name)	psi-mi:"MI:0424"(protein kinase assay)	Mazanka et al. (2008)	pubmed:18715118|doi:10.1371/journal.pbio.0060203|imex:IM-9311	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15722429|imex:IM-9311-1|dip:DIP-87797E	-	-	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000005105|refseq:NP_014238.3|dip:DIP-5656N|ensemblfungi:YNL161W(gene)|ensemblfungi:YNL161W_mRNA(transcript)|go:"GO:0000131"(incipient cellular bud site)|go:"GO:0000920"(septum digestion after cytokinesis)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005628"(prospore membrane)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005933"(cellular bud)|go:"GO:0005934"(cellular bud tip)|go:"GO:0005935"(cellular bud neck)|go:"GO:0005938"(cell cortex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007118"(budding cell apical bud growth)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0030950"(establishment or maintenance of actin cytoskeleton polarity)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042802"(identical protein binding)|go:"GO:0043332"(mating projection tip)|go:"GO:0050708"(regulation of protein secretion)|go:"GO:0060237"(regulation of fungal-type cell wall organization)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:4LQP|rcsb pdb:4LQQ|rcsb pdb:4LQS|rcsb pdb:5NCL|rcsb pdb:5NCM	refseq:NP_013232.1|sgd:S000004121|dip:DIP-2012N|mint:P21192|ensemblfungi:YLR131C(gene)|ensemblfungi:YLR131C_mRNA(transcript)|go:"GO:0000083"(regulation of transcription involved in G1/S transition of mitotic cell cycle)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0060196"(positive regulation of antisense RNA transcription)|go:"GO:2001043"(positive regulation of septum digestion after cytokinesis)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236	psi-mi:"MI:0465"(dip)	crc64:87EBCD2C3C96EE11	crc64:A7FCA8C506A2FD75	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/06	2017/08/10	rogid:pNqqn26/5iKdHk4g9hhRcrOSMa0559292	rogid:iOLMyumnA219VIBA9AXaZd9NI0c559292	rigid:wf8f9yo/fWlghgI/o1r+6kc2apA	false	ha tag:c-c	binding-associated region:42-242|mutation disrupting interaction:137-137,122-122,113-113|mutation disrupting interaction:137-137,117-117,113-113|glutathione s tranferase tag:n-n	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P30822	uniprotkb:P21192	intact:EBI-20589|uniprotkb:D6VV01|ensemblfungi:YGR218W	intact:EBI-2073|uniprotkb:D6VYC6|ensemblfungi:YLR131C	psi-mi:xpo1_yeast(display_long)|uniprotkb:CRM1(gene name)|psi-mi:CRM1(display_short)|uniprotkb:KAP124(gene name synonym)|uniprotkb:YGR218W(locus name)|uniprotkb:G8514(orf name)|uniprotkb:XPO1(gene name synonym)|uniprotkb:Chromosome region maintenance protein 1(gene name synonym)|uniprotkb:Karyopherin-124(gene name synonym)	psi-mi:ace2_yeast(display_long)|uniprotkb:ACE2(gene name)|psi-mi:ACE2(display_short)|uniprotkb:L3123(orf name)|uniprotkb:L9606.10(orf name)|uniprotkb:YLR131C(locus name)	psi-mi:"MI:0096"(pull down)	Mazanka et al. (2008)	pubmed:18715118|doi:10.1371/journal.pbio.0060203|imex:IM-9311	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15722462|imex:IM-9311-2|dip:DIP-4083E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_011734.3|sgd:S000003450|go:"GO:0030621"(U4 snRNA binding)|go:"GO:0030623"(U5 snRNA binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0034501"(protein localization to kinetochore)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051168"(nuclear export)|go:"GO:0061608"(nuclear import signal receptor activity)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013598(Exportin-1/Importin-beta-like)|interpro:IPR014877(Exportin 1, C-terminal)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040485|interpro:IPR041123|interpro:IPR041235|rcsb pdb:3M1I|rcsb pdb:3VYC|rcsb pdb:3WYF|rcsb pdb:3WYG|rcsb pdb:4GMX|rcsb pdb:4GPT|rcsb pdb:4HAT|rcsb pdb:4HAU|rcsb pdb:4HAV|rcsb pdb:4HAW|rcsb pdb:4HAX|go:"GO:0030620"(U2 snRNA binding)|rcsb pdb:4HAY|rcsb pdb:4HAZ|rcsb pdb:4HB0|rcsb pdb:4HB2|rcsb pdb:4HB3|rcsb pdb:4HB4|rcsb pdb:5DH9|rcsb pdb:5DHA|rcsb pdb:5DHF|rcsb pdb:5DI9|rcsb pdb:5DIF|rcsb pdb:5JLJ|rcsb pdb:5UWH|rcsb pdb:5UWI|rcsb pdb:5UWJ|rcsb pdb:5UWO|rcsb pdb:5UWP|rcsb pdb:5UWQ|rcsb pdb:5UWR|rcsb pdb:5UWS|rcsb pdb:5UWT|rcsb pdb:5UWU|rcsb pdb:5UWW|rcsb pdb:5XOJ|rcsb pdb:5YRO|rcsb pdb:5YST|rcsb pdb:5YSU|rcsb pdb:5YTB|rcsb pdb:5ZPU|rcsb pdb:6A38|rcsb pdb:6A3A|rcsb pdb:6A3B|rcsb pdb:6A3C|rcsb pdb:6A3E|rcsb pdb:6CIT|rcsb pdb:6XJS|rcsb pdb:6XJT|rcsb pdb:6XJU|rcsb pdb:7L5E|reactome:R-SCE-5687128|rcsb pdb:6KFT|rcsb pdb:6LQ9|rcsb pdb:6M60|rcsb pdb:6M6X|rcsb pdb:6X2M|rcsb pdb:6X2O|rcsb pdb:6X2P|rcsb pdb:6X2R|rcsb pdb:6X2S|rcsb pdb:6X2U|rcsb pdb:6X2V|rcsb pdb:6X2W|rcsb pdb:6X2X|rcsb pdb:6X2Y|rcsb pdb:6XJP|rcsb pdb:6XJR|ensemblfungi:YGR218W(gene)|ensemblfungi:YGR218W_mRNA(transcript)|go:"GO:0000055"(ribosomal large subunit export from nucleus)|go:"GO:0000056"(ribosomal small subunit export from nucleus)|go:"GO:0000776"(kinetochore)|go:"GO:0005049"(nuclear export signal receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005816"(spindle pole body)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0017070"(U6 snRNA binding)|go:"GO:0030619"(U1 snRNA binding)|dip:DIP-2244N|mint:P30822	refseq:NP_013232.1|sgd:S000004121|dip:DIP-2012N|mint:P21192|ensemblfungi:YLR131C(gene)|ensemblfungi:YLR131C_mRNA(transcript)|go:"GO:0000083"(regulation of transcription involved in G1/S transition of mitotic cell cycle)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0060196"(positive regulation of antisense RNA transcription)|go:"GO:2001043"(positive regulation of septum digestion after cytokinesis)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236	psi-mi:"MI:0465"(dip)	crc64:A81833C7F60F5202	crc64:A7FCA8C506A2FD75	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/06	2017/08/10	rogid:9YWJL+G+yiF+OkUyDF3VTfDYLag559292	rogid:iOLMyumnA219VIBA9AXaZd9NI0c559292	rigid:GFIkIOqOolEQUz7lRc3JWPdYtno	false	-	biotin tag:n-n|mutation decreasing interaction:127-127|binding-associated region:122-150	-	-	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)
uniprotkb:P30822	uniprotkb:P21192	intact:EBI-20589|uniprotkb:D6VV01|ensemblfungi:YGR218W	intact:EBI-2073|uniprotkb:D6VYC6|ensemblfungi:YLR131C	psi-mi:xpo1_yeast(display_long)|uniprotkb:CRM1(gene name)|psi-mi:CRM1(display_short)|uniprotkb:KAP124(gene name synonym)|uniprotkb:YGR218W(locus name)|uniprotkb:G8514(orf name)|uniprotkb:XPO1(gene name synonym)|uniprotkb:Chromosome region maintenance protein 1(gene name synonym)|uniprotkb:Karyopherin-124(gene name synonym)	psi-mi:ace2_yeast(display_long)|uniprotkb:ACE2(gene name)|psi-mi:ACE2(display_short)|uniprotkb:L3123(orf name)|uniprotkb:L9606.10(orf name)|uniprotkb:YLR131C(locus name)	psi-mi:"MI:0096"(pull down)	Mazanka et al. (2008)	pubmed:18715118|doi:10.1371/journal.pbio.0060203|imex:IM-9311	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15722486|imex:IM-9311-3|dip:DIP-4083E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_011734.3|sgd:S000003450|go:"GO:0030621"(U4 snRNA binding)|go:"GO:0030623"(U5 snRNA binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0034501"(protein localization to kinetochore)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051168"(nuclear export)|go:"GO:0061608"(nuclear import signal receptor activity)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013598(Exportin-1/Importin-beta-like)|interpro:IPR014877(Exportin 1, C-terminal)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040485|interpro:IPR041123|interpro:IPR041235|rcsb pdb:3M1I|rcsb pdb:3VYC|rcsb pdb:3WYF|rcsb pdb:3WYG|rcsb pdb:4GMX|rcsb pdb:4GPT|rcsb pdb:4HAT|rcsb pdb:4HAU|rcsb pdb:4HAV|rcsb pdb:4HAW|rcsb pdb:4HAX|go:"GO:0030620"(U2 snRNA binding)|rcsb pdb:4HAY|rcsb pdb:4HAZ|rcsb pdb:4HB0|rcsb pdb:4HB2|rcsb pdb:4HB3|rcsb pdb:4HB4|rcsb pdb:5DH9|rcsb pdb:5DHA|rcsb pdb:5DHF|rcsb pdb:5DI9|rcsb pdb:5DIF|rcsb pdb:5JLJ|rcsb pdb:5UWH|rcsb pdb:5UWI|rcsb pdb:5UWJ|rcsb pdb:5UWO|rcsb pdb:5UWP|rcsb pdb:5UWQ|rcsb pdb:5UWR|rcsb pdb:5UWS|rcsb pdb:5UWT|rcsb pdb:5UWU|rcsb pdb:5UWW|rcsb pdb:5XOJ|rcsb pdb:5YRO|rcsb pdb:5YST|rcsb pdb:5YSU|rcsb pdb:5YTB|rcsb pdb:5ZPU|rcsb pdb:6A38|rcsb pdb:6A3A|rcsb pdb:6A3B|rcsb pdb:6A3C|rcsb pdb:6A3E|rcsb pdb:6CIT|rcsb pdb:6XJS|rcsb pdb:6XJT|rcsb pdb:6XJU|rcsb pdb:7L5E|reactome:R-SCE-5687128|rcsb pdb:6KFT|rcsb pdb:6LQ9|rcsb pdb:6M60|rcsb pdb:6M6X|rcsb pdb:6X2M|rcsb pdb:6X2O|rcsb pdb:6X2P|rcsb pdb:6X2R|rcsb pdb:6X2S|rcsb pdb:6X2U|rcsb pdb:6X2V|rcsb pdb:6X2W|rcsb pdb:6X2X|rcsb pdb:6X2Y|rcsb pdb:6XJP|rcsb pdb:6XJR|ensemblfungi:YGR218W(gene)|ensemblfungi:YGR218W_mRNA(transcript)|go:"GO:0000055"(ribosomal large subunit export from nucleus)|go:"GO:0000056"(ribosomal small subunit export from nucleus)|go:"GO:0000776"(kinetochore)|go:"GO:0005049"(nuclear export signal receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005816"(spindle pole body)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0017070"(U6 snRNA binding)|go:"GO:0030619"(U1 snRNA binding)|dip:DIP-2244N|mint:P30822	refseq:NP_013232.1|sgd:S000004121|dip:DIP-2012N|mint:P21192|ensemblfungi:YLR131C(gene)|ensemblfungi:YLR131C_mRNA(transcript)|go:"GO:0000083"(regulation of transcription involved in G1/S transition of mitotic cell cycle)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0060196"(positive regulation of antisense RNA transcription)|go:"GO:2001043"(positive regulation of septum digestion after cytokinesis)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236	psi-mi:"MI:0465"(dip)	crc64:A81833C7F60F5202	crc64:A7FCA8C506A2FD75	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/06	2017/08/10	rogid:9YWJL+G+yiF+OkUyDF3VTfDYLag559292	rogid:iOLMyumnA219VIBA9AXaZd9NI0c559292	rigid:GFIkIOqOolEQUz7lRc3JWPdYtno	false	-	binding-associated region:122-150|mutation disrupting interaction:137-137,122-122|mutation disrupting interaction:127-127|glutathione s tranferase tag:n-n|mutation decreasing interaction:122-122|mutation decreasing interaction:137-137	-	-	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)