#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P41412 uniprotkb:O42913 intact:EBI-1149177|uniprotkb:Q02300|ensemblfungi:"SPAC22F3.09c.1:pep" intact:EBI-15720278|ensemblfungi:"SPBC16A3.07c.1:pep" psi-mi:res2_schpo(display_long)|uniprotkb:res2(gene name)|psi-mi:res2(display_short)|uniprotkb:pct1(gene name synonym)|uniprotkb:SPAC22F3.09c(orf name) psi-mi:nrm1_schpo(display_long)|uniprotkb:Negative regulator of MBF targets 1(gene name synonym)|uniprotkb:SPBC16A3.07c(orf name)|uniprotkb:nrm1(gene name)|psi-mi:nrm1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) de et al. (2008) pubmed:18682565|doi:10.1073/pnas.0801106105|imex:IM-9421 taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15720297|imex:IM-9421-1|dip:DIP-88010E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_593032.1|ensemblfungi:SPAC22F3.09c(gene)|ensemblfungi:SPAC22F3.09c.1(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0030907"(MBF transcription complex)|go:"GO:0033309"(SBF transcription complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051445"(regulation of meiotic cell cycle)|go:"GO:0071931"(positive regulation of transcription involved in G1/S transition of mitotic cell cycle)|interpro:IPR002110(Ankyrin)|interpro:IPR003163(DNA-binding, yeast)|interpro:IPR018004|interpro:IPR029793|interpro:IPR036770|interpro:IPR036887|dip:DIP-35569N ensemblfungi:SPBC16A3.07c.1(transcript)|go:"GO:0000083"(regulation of transcription involved in G1/S transition of mitotic cell cycle)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|interpro:IPR013734(Nrm1)|ensemblfungi:SPBC16A3.07c(gene)|dip:DIP-46173N|refseq:NP_596782.1 psi-mi:"MI:0465"(dip) crc64:1159312B63E475E4 crc64:783CD47C85CD9D75 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4896(schpm)|taxid:4896("Schizosaccharomyces pombe (fission yeast)") - 2017/08/05 2017/08/10 rogid:Bt8hchyEhUudF6B8+g/Vna0gU/s284812 rogid:2YaijkwxHpq8n7oLgmhIZJUUfnA284812 rigid:3aBCxePWmw1kVko9wCqc2DJkeQs false myc tag:?-? - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P41412 uniprotkb:O42913 intact:EBI-1149177|uniprotkb:Q02300|ensemblfungi:"SPAC22F3.09c.1:pep" intact:EBI-15720278|ensemblfungi:"SPBC16A3.07c.1:pep" psi-mi:res2_schpo(display_long)|uniprotkb:res2(gene name)|psi-mi:res2(display_short)|uniprotkb:pct1(gene name synonym)|uniprotkb:SPAC22F3.09c(orf name) psi-mi:nrm1_schpo(display_long)|uniprotkb:Negative regulator of MBF targets 1(gene name synonym)|uniprotkb:SPBC16A3.07c(orf name)|uniprotkb:nrm1(gene name)|psi-mi:nrm1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) de et al. (2008) pubmed:18682565|doi:10.1073/pnas.0801106105|imex:IM-9421 taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15720338|imex:IM-9421-3|dip:DIP-88010E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_593032.1|ensemblfungi:SPAC22F3.09c(gene)|ensemblfungi:SPAC22F3.09c.1(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0030907"(MBF transcription complex)|go:"GO:0033309"(SBF transcription complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051445"(regulation of meiotic cell cycle)|go:"GO:0071931"(positive regulation of transcription involved in G1/S transition of mitotic cell cycle)|interpro:IPR002110(Ankyrin)|interpro:IPR003163(DNA-binding, yeast)|interpro:IPR018004|interpro:IPR029793|interpro:IPR036770|interpro:IPR036887|dip:DIP-35569N ensemblfungi:SPBC16A3.07c.1(transcript)|go:"GO:0000083"(regulation of transcription involved in G1/S transition of mitotic cell cycle)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|interpro:IPR013734(Nrm1)|ensemblfungi:SPBC16A3.07c(gene)|dip:DIP-46173N|refseq:NP_596782.1 psi-mi:"MI:0465"(dip) crc64:1159312B63E475E4 crc64:783CD47C85CD9D75 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4896(schpm)|taxid:4896("Schizosaccharomyces pombe (fission yeast)") - 2017/08/05 2017/08/10 rogid:Bt8hchyEhUudF6B8+g/Vna0gU/s284812 rogid:2YaijkwxHpq8n7oLgmhIZJUUfnA284812 rigid:3aBCxePWmw1kVko9wCqc2DJkeQs false myc tag:?-? ha tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q09170 uniprotkb:O42913 intact:EBI-3650524|uniprotkb:O42642|ensemblfungi:"SPCC18B5.11c.1:pep" intact:EBI-15720278|ensemblfungi:"SPBC16A3.07c.1:pep" psi-mi:cds1_schpo(display_long)|uniprotkb:cds1(gene name)|psi-mi:cds1(display_short)|uniprotkb:Checkpoint kinase cds1(gene name synonym)|uniprotkb:SPCC18B5.11c(orf name) psi-mi:nrm1_schpo(display_long)|uniprotkb:Negative regulator of MBF targets 1(gene name synonym)|uniprotkb:SPBC16A3.07c(orf name)|uniprotkb:nrm1(gene name)|psi-mi:nrm1(display_short) psi-mi:"MI:0424"(protein kinase assay) de et al. (2008) pubmed:18682565|doi:10.1073/pnas.0801106105|imex:IM-9421 taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15720359|imex:IM-9421-4|dip:DIP-88011E - - psi-mi:"MI:0501"(enzyme) psi-mi:"MI:0502"(enzyme target) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_587941.1|dip:DIP-46174N|ensemblfungi:SPCC18B5.11c(gene)|ensemblfungi:SPCC18B5.11c.1(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0031573"(mitotic intra-S DNA damage checkpoint signaling)|go:"GO:0032153"(cell division site)|go:"GO:0033314"(mitotic DNA replication checkpoint signaling)|go:"GO:0033315"(meiotic G2/MI DNA replication checkpoint signaling)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1903466"(regulation of mitotic DNA replication initiation)|interpro:IPR000253(Forkhead-associated)|interpro:IPR000719(Protein kinase, core)|reactome:R-SPO-5693565|reactome:R-SPO-69473|reactome:R-SPO-69601|reactome:R-SPO-75035 ensemblfungi:SPBC16A3.07c.1(transcript)|go:"GO:0000083"(regulation of transcription involved in G1/S transition of mitotic cell cycle)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|interpro:IPR013734(Nrm1)|ensemblfungi:SPBC16A3.07c(gene)|dip:DIP-46173N|refseq:NP_596782.1 psi-mi:"MI:0465"(dip) "mimix:comment":not sure about protein origin|crc64:4CEB963D3376DB54 crc64:783CD47C85CD9D75 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/05 2017/08/10 rogid:d1mVWYYgcoQxFOJVRsTwGfuDQbM284812 rogid:2YaijkwxHpq8n7oLgmhIZJUUfnA284812 rigid:h73pLWdrv861Hq6R01+px4MTxHU false glutathione s tranferase tag:n-n - - - psi-mi:"MI:0833"(autoradiography) psi-mi:"MI:0833"(autoradiography) uniprotkb:P01129 uniprotkb:O42913 intact:EBI-1009350|uniprotkb:Q9UU04|ensemblfungi:"SPBC336.12c.1:pep" intact:EBI-15720278|ensemblfungi:"SPBC16A3.07c.1:pep" psi-mi:cdc10_schpo(display_long)|uniprotkb:cdc10(gene name)|psi-mi:cdc10(display_short)|uniprotkb:SPBC336.12c(orf name) psi-mi:nrm1_schpo(display_long)|uniprotkb:Negative regulator of MBF targets 1(gene name synonym)|uniprotkb:SPBC16A3.07c(orf name)|uniprotkb:nrm1(gene name)|psi-mi:nrm1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) de et al. (2008) pubmed:18682565|doi:10.1073/pnas.0801106105|imex:IM-9421 taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15720316|imex:IM-9421-2|dip:DIP-88009E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_596132.1|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|ensemblfungi:SPBC336.12c(gene)|ensemblfungi:SPBC336.12c.1(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000083"(regulation of transcription involved in G1/S transition of mitotic cell cycle)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009303"(rRNA transcription)|go:"GO:0030907"(MBF transcription complex)|go:"GO:0033309"(SBF transcription complex)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051301"(cell division)|go:"GO:0071931"(positive regulation of transcription involved in G1/S transition of mitotic cell cycle)|interpro:IPR002110(Ankyrin)|interpro:IPR003163(DNA-binding, yeast)|interpro:IPR018004|interpro:IPR036770|interpro:IPR036887|dip:DIP-353N ensemblfungi:SPBC16A3.07c.1(transcript)|go:"GO:0000083"(regulation of transcription involved in G1/S transition of mitotic cell cycle)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|interpro:IPR013734(Nrm1)|ensemblfungi:SPBC16A3.07c(gene)|dip:DIP-46173N|refseq:NP_596782.1 psi-mi:"MI:0465"(dip) crc64:0E514EE1BE218EFA crc64:783CD47C85CD9D75 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4896(schpm)|taxid:4896("Schizosaccharomyces pombe (fission yeast)") - 2017/08/05 2017/08/10 rogid:3uQ3wPJ5PLO3N2b6Tch1q+nfc8M284812 rogid:2YaijkwxHpq8n7oLgmhIZJUUfnA284812 rigid:iUsWeB724e4FEVxfXphQeMizz7Y false myc tag:?-? ha tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q09170 uniprotkb:O42913 intact:EBI-3650524|uniprotkb:O42642|ensemblfungi:"SPCC18B5.11c.1:pep" intact:EBI-15720278|ensemblfungi:"SPBC16A3.07c.1:pep" psi-mi:cds1_schpo(display_long)|uniprotkb:cds1(gene name)|psi-mi:cds1(display_short)|uniprotkb:Checkpoint kinase cds1(gene name synonym)|uniprotkb:SPCC18B5.11c(orf name) psi-mi:nrm1_schpo(display_long)|uniprotkb:Negative regulator of MBF targets 1(gene name synonym)|uniprotkb:SPBC16A3.07c(orf name)|uniprotkb:nrm1(gene name)|psi-mi:nrm1(display_short) psi-mi:"MI:0096"(pull down) de et al. (2008) pubmed:18682565|doi:10.1073/pnas.0801106105|imex:IM-9421 taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15720378|imex:IM-9421-5|dip:DIP-88011E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_587941.1|dip:DIP-46174N|ensemblfungi:SPCC18B5.11c(gene)|ensemblfungi:SPCC18B5.11c.1(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0031573"(mitotic intra-S DNA damage checkpoint signaling)|go:"GO:0032153"(cell division site)|go:"GO:0033314"(mitotic DNA replication checkpoint signaling)|go:"GO:0033315"(meiotic G2/MI DNA replication checkpoint signaling)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1903466"(regulation of mitotic DNA replication initiation)|interpro:IPR000253(Forkhead-associated)|interpro:IPR000719(Protein kinase, core)|reactome:R-SPO-5693565|reactome:R-SPO-69473|reactome:R-SPO-69601|reactome:R-SPO-75035 ensemblfungi:SPBC16A3.07c.1(transcript)|go:"GO:0000083"(regulation of transcription involved in G1/S transition of mitotic cell cycle)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|interpro:IPR013734(Nrm1)|ensemblfungi:SPBC16A3.07c(gene)|dip:DIP-46173N|refseq:NP_596782.1 psi-mi:"MI:0465"(dip) "mimix:comment":not sure about protein origin|crc64:4CEB963D3376DB54 crc64:783CD47C85CD9D75 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/05 2017/08/10 rogid:d1mVWYYgcoQxFOJVRsTwGfuDQbM284812 rogid:2YaijkwxHpq8n7oLgmhIZJUUfnA284812 rigid:h73pLWdrv861Hq6R01+px4MTxHU false glutathione s tranferase tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)