#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P07663-1 uniprotkb:O76324 intact:EBI-15718452 intact:EBI-189923|uniprotkb:A4V3P5|uniprotkb:Q0KHY4|uniprotkb:Q9V462|ensemblmetazoa:FBpp0085104|ensemblmetazoa:FBpp0085105|ensemblmetazoa:FBpp0085106|ensemblmetazoa:FBpp0306615|ensemblmetazoa:FBpp0422974 psi-mi:p07663-1(display_long)|uniprotkb:per(gene name)|psi-mi:per(display_short)|uniprotkb:Protein clock-6(gene name synonym)|uniprotkb:CG2647(orf name)|uniprotkb:perA(isoform synonym) psi-mi:dco_drome(display_long)|uniprotkb:dco(gene name)|psi-mi:dco(display_short)|uniprotkb:dbt(gene name synonym)|uniprotkb:Protein double-time(gene name synonym)|uniprotkb:CG2048(orf name) psi-mi:"MI:0424"(protein kinase assay) Kivimäe et al. (2008) pubmed:18666831|doi:10.1371/journal.pbio.0060183|imex:IM-9308 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15718462|imex:IM-9308-1|dip:DIP-87792E - - psi-mi:"MI:0502"(enzyme target) psi-mi:"MI:0501"(enzyme) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-496170(isoform-parent) refseq:NP_524602.1|refseq:NP_733414.1|refseq:NP_733415.1|flybase:FBgn0002413|refseq:NP_001263132.1|dip:DIP-46048N|ensemblmetazoa:FBgn0002413(gene)|ensemblmetazoa:FBtr0085742(transcript)|ensemblmetazoa:FBtr0085743(transcript)|ensemblmetazoa:FBtr0085744(transcript)|ensemblmetazoa:FBtr0334548(transcript)|ensemblmetazoa:FBtr0473370(transcript)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006897"(endocytosis)|go:"GO:0007154"(cell communication)|go:"GO:0007446"(imaginal disc growth)|go:"GO:0007555"(regulation of ecdysteroid secretion)|go:"GO:0007623"(circadian rhythm)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016310"(phosphorylation)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0035332"(positive regulation of hippo signaling)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044297"(cell body)|go:"GO:0045475"(locomotor rhythm)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0045880"(positive regulation of smoothened signaling pathway)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048148"(behavioral response to cocaine)|go:"GO:0051781"(positive regulation of cell division)|go:"GO:0071482"(cellular response to light stimulus)|go:"GO:0090175"(regulation of establishment of planar polarity)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|reactome:R-DME-201688|reactome:R-DME-209155|reactome:R-DME-209159|reactome:R-DME-209190|reactome:R-DME-209214|reactome:R-DME-209360|reactome:R-DME-209396|reactome:R-DME-209413|reactome:R-DME-209440|reactome:R-DME-209461|reactome:R-DME-390023|reactome:R-DME-390150|reactome:R-DME-432395|reactome:R-DME-432490|reactome:R-DME-432501|reactome:R-DME-432524|reactome:R-DME-432553|reactome:R-DME-432620|reactome:R-DME-538898 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/05 2017/08/10 rogid:+l/mg+2MJForY5dORYWnWsVAhNI7227 rogid:ei2gU3lKLNgH3s2sv4AHRE7OM8Q7227 rigid:XTKpmBkRVvbHYup6RJgmkYbhzkY false sufficient binding region:149-365|sufficient binding region:570-645|sufficient binding region:1101-1224 - - - psi-mi:"MI:0821"(molecular weight estimation by autoradiography) psi-mi:"MI:0821"(molecular weight estimation by autoradiography)