#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P0DJ88 uniprotkb:O08816 intact:EBI-10039462|uniprotkb:Q8X2D5|uniprotkb:P0DJ89 intact:EBI-6142604 psi-mi:esfu2_eco57(display_long)|uniprotkb:"espF(U)"(gene name)|psi-mi:"espF(U)"(display_short)|uniprotkb:tccP(gene name synonym)|uniprotkb:EspF-like protein encoded on prophage U(gene name synonym)|uniprotkb:Tir-cytoskeleton coupling protein TccP(gene name synonym)|uniprotkb:ECs2715(locus name) psi-mi:wasl_rat(display_long)|uniprotkb:Wasl(gene name)|psi-mi:Wasl(display_short) psi-mi:"MI:0096"(pull down) Sallee et al. (2008) pubmed:18650806|doi:10.1038/nature07170|imex:IM-17993 taxid:83334(eco57)|taxid:83334("Escherichia coli O157:H7") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15717659|imex:IM-17993-1|dip:DIP-189577E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR006891(EspF protein)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0009405"(obsolete pathogenesis)|refseq:NP_310742.1|refseq:WP_010917831.1|go:"GO:0005576"(extracellular region)|rcsb pdb:2K42|rcsb pdb:2KXC|rcsb pdb:2LNH|dip:DIP-59949N mint:O08816|rgd:735144|dip:DIP-17016N|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0006900"(vesicle budding from membrane)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0009617"(response to bacterium)|go:"GO:0010324"(membrane invagination)|go:"GO:0016050"(vesicle organization)|go:"GO:0030027"(lamellipodium)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030048"(actin filament-based movement)|go:"GO:0030050"(vesicle transport along actin filament)|go:"GO:0030478"(actin cap)|go:"GO:0031252"(cell leading edge)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0034629"|go:"GO:0042802"(identical protein binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050921"(positive regulation of chemotaxis)|go:"GO:0051301"(cell division)|go:"GO:0051491"(positive regulation of filopodium assembly)|go:"GO:0051653"(spindle localization)|go:"GO:0060491"(regulation of cell projection assembly)|go:"GO:0060997"(dendritic spine morphogenesis)|go:"GO:0097320"(plasma membrane tubulation)|go:"GO:0098794"(postsynapse)|go:"GO:0098974"(postsynaptic actin cytoskeleton organization)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1903526"(negative regulation of membrane tubulation)|go:"GO:2000370"(positive regulation of clathrin-dependent endocytosis)|go:"GO:2000402"(negative regulation of lymphocyte migration)|go:"GO:2000601"(positive regulation of Arp2/3 complex-mediated actin nucleation)|interpro:IPR000095(PAK-box/P21-Rho-binding)|interpro:IPR000697(EVH1)|interpro:IPR003124(Actin-binding WH2)|interpro:IPR011026(Wiscott-Aldrich syndrome, C-terminal)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR030214|interpro:IPR033927|interpro:IPR036936|rcsb pdb:1MKE|rcsb pdb:2IFS|go:"GO:0000139"(Golgi membrane) psi-mi:"MI:0465"(dip) caution:This sequence has been withdrawn from Uniprot. - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/05 2017/08/10 rogid:WARX33S3/G5CXG922GIjofxveNc83334 rogid:lKgHtUQQEc8C14/X9D8WOvry2iM10116 rigid:c0LdFPSux2XWLpoaenuBKr/Ts08 false binding-associated region:221-267|his tag:n-n sufficient binding region:228-270|glutathione s tranferase tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:O08816 uniprotkb:O08816 intact:EBI-6142604 intact:EBI-6142604 psi-mi:wasl_rat(display_long)|uniprotkb:Wasl(gene name)|psi-mi:Wasl(display_short) psi-mi:wasl_rat(display_long)|uniprotkb:Wasl(gene name)|psi-mi:Wasl(display_short) psi-mi:"MI:0096"(pull down) Sallee et al. (2008) pubmed:18650806|doi:10.1038/nature07170|imex:IM-17993 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15717707|imex:IM-17993-3|dip:DIP-189578E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:O08816|rgd:735144|dip:DIP-17016N|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0006900"(vesicle budding from membrane)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0009617"(response to bacterium)|go:"GO:0010324"(membrane invagination)|go:"GO:0016050"(vesicle organization)|go:"GO:0030027"(lamellipodium)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030048"(actin filament-based movement)|go:"GO:0030050"(vesicle transport along actin filament)|go:"GO:0030478"(actin cap)|go:"GO:0031252"(cell leading edge)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0034629"|go:"GO:0042802"(identical protein binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050921"(positive regulation of chemotaxis)|go:"GO:0051301"(cell division)|go:"GO:0051491"(positive regulation of filopodium assembly)|go:"GO:0051653"(spindle localization)|go:"GO:0060491"(regulation of cell projection assembly)|go:"GO:0060997"(dendritic spine morphogenesis)|go:"GO:0097320"(plasma membrane tubulation)|go:"GO:0098794"(postsynapse)|go:"GO:0098974"(postsynaptic actin cytoskeleton organization)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1903526"(negative regulation of membrane tubulation)|go:"GO:2000370"(positive regulation of clathrin-dependent endocytosis)|go:"GO:2000402"(negative regulation of lymphocyte migration)|go:"GO:2000601"(positive regulation of Arp2/3 complex-mediated actin nucleation)|interpro:IPR000095(PAK-box/P21-Rho-binding)|interpro:IPR000697(EVH1)|interpro:IPR003124(Actin-binding WH2)|interpro:IPR011026(Wiscott-Aldrich syndrome, C-terminal)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR030214|interpro:IPR033927|interpro:IPR036936|rcsb pdb:1MKE|rcsb pdb:2IFS|go:"GO:0000139"(Golgi membrane) mint:O08816|rgd:735144|dip:DIP-17016N|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0006900"(vesicle budding from membrane)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0009617"(response to bacterium)|go:"GO:0010324"(membrane invagination)|go:"GO:0016050"(vesicle organization)|go:"GO:0030027"(lamellipodium)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030048"(actin filament-based movement)|go:"GO:0030050"(vesicle transport along actin filament)|go:"GO:0030478"(actin cap)|go:"GO:0031252"(cell leading edge)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0034629"|go:"GO:0042802"(identical protein binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050921"(positive regulation of chemotaxis)|go:"GO:0051301"(cell division)|go:"GO:0051491"(positive regulation of filopodium assembly)|go:"GO:0051653"(spindle localization)|go:"GO:0060491"(regulation of cell projection assembly)|go:"GO:0060997"(dendritic spine morphogenesis)|go:"GO:0097320"(plasma membrane tubulation)|go:"GO:0098794"(postsynapse)|go:"GO:0098974"(postsynaptic actin cytoskeleton organization)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1903526"(negative regulation of membrane tubulation)|go:"GO:2000370"(positive regulation of clathrin-dependent endocytosis)|go:"GO:2000402"(negative regulation of lymphocyte migration)|go:"GO:2000601"(positive regulation of Arp2/3 complex-mediated actin nucleation)|interpro:IPR000095(PAK-box/P21-Rho-binding)|interpro:IPR000697(EVH1)|interpro:IPR003124(Actin-binding WH2)|interpro:IPR011026(Wiscott-Aldrich syndrome, C-terminal)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR030214|interpro:IPR033927|interpro:IPR036936|rcsb pdb:1MKE|rcsb pdb:2IFS|go:"GO:0000139"(Golgi membrane) psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/05 2017/08/10 rogid:lKgHtUQQEc8C14/X9D8WOvry2iM10116 rogid:lKgHtUQQEc8C14/X9D8WOvry2iM10116 rigid:S0jbDfFJbGQoQNDtrvT2Dzi44EM false binding-associated region:190-274|his tag:n-n glutathione s tranferase tag:n-n|binding-associated region:392-501 - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P0DJ88 uniprotkb:O08816 intact:EBI-10039462|uniprotkb:Q8X2D5|uniprotkb:P0DJ89 intact:EBI-6142604 psi-mi:esfu2_eco57(display_long)|uniprotkb:"espF(U)"(gene name)|psi-mi:"espF(U)"(display_short)|uniprotkb:tccP(gene name synonym)|uniprotkb:EspF-like protein encoded on prophage U(gene name synonym)|uniprotkb:Tir-cytoskeleton coupling protein TccP(gene name synonym)|uniprotkb:ECs2715(locus name) psi-mi:wasl_rat(display_long)|uniprotkb:Wasl(gene name)|psi-mi:Wasl(display_short) psi-mi:"MI:0096"(pull down) Sallee et al. (2008) pubmed:18650806|doi:10.1038/nature07170|imex:IM-17993 taxid:83334(eco57)|taxid:83334("Escherichia coli O157:H7") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15717732|imex:IM-17993-4|dip:DIP-189577E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR006891(EspF protein)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0009405"(obsolete pathogenesis)|refseq:NP_310742.1|refseq:WP_010917831.1|go:"GO:0005576"(extracellular region)|rcsb pdb:2K42|rcsb pdb:2KXC|rcsb pdb:2LNH|dip:DIP-59949N mint:O08816|rgd:735144|dip:DIP-17016N|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0006900"(vesicle budding from membrane)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0009617"(response to bacterium)|go:"GO:0010324"(membrane invagination)|go:"GO:0016050"(vesicle organization)|go:"GO:0030027"(lamellipodium)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030048"(actin filament-based movement)|go:"GO:0030050"(vesicle transport along actin filament)|go:"GO:0030478"(actin cap)|go:"GO:0031252"(cell leading edge)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0034629"|go:"GO:0042802"(identical protein binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050921"(positive regulation of chemotaxis)|go:"GO:0051301"(cell division)|go:"GO:0051491"(positive regulation of filopodium assembly)|go:"GO:0051653"(spindle localization)|go:"GO:0060491"(regulation of cell projection assembly)|go:"GO:0060997"(dendritic spine morphogenesis)|go:"GO:0097320"(plasma membrane tubulation)|go:"GO:0098794"(postsynapse)|go:"GO:0098974"(postsynaptic actin cytoskeleton organization)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1903526"(negative regulation of membrane tubulation)|go:"GO:2000370"(positive regulation of clathrin-dependent endocytosis)|go:"GO:2000402"(negative regulation of lymphocyte migration)|go:"GO:2000601"(positive regulation of Arp2/3 complex-mediated actin nucleation)|interpro:IPR000095(PAK-box/P21-Rho-binding)|interpro:IPR000697(EVH1)|interpro:IPR003124(Actin-binding WH2)|interpro:IPR011026(Wiscott-Aldrich syndrome, C-terminal)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR030214|interpro:IPR033927|interpro:IPR036936|rcsb pdb:1MKE|rcsb pdb:2IFS|go:"GO:0000139"(Golgi membrane) psi-mi:"MI:0465"(dip) caution:This sequence has been withdrawn from Uniprot. - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/05 2017/08/10 rogid:WARX33S3/G5CXG922GIjofxveNc83334 rogid:lKgHtUQQEc8C14/X9D8WOvry2iM10116 rigid:c0LdFPSux2XWLpoaenuBKr/Ts08 false sufficient binding region:221-237|glutathione s tranferase tag:n-n|sufficient binding region:80-173 his tag:n-n|binding-associated region:190-274 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P0DJ88 uniprotkb:O08816 intact:EBI-10039462|uniprotkb:Q8X2D5|uniprotkb:P0DJ89 intact:EBI-6142604 psi-mi:esfu2_eco57(display_long)|uniprotkb:"espF(U)"(gene name)|psi-mi:"espF(U)"(display_short)|uniprotkb:tccP(gene name synonym)|uniprotkb:EspF-like protein encoded on prophage U(gene name synonym)|uniprotkb:Tir-cytoskeleton coupling protein TccP(gene name synonym)|uniprotkb:ECs2715(locus name) psi-mi:wasl_rat(display_long)|uniprotkb:Wasl(gene name)|psi-mi:Wasl(display_short) psi-mi:"MI:0053"(fluorescence polarization spectroscopy) Sallee et al. (2008) pubmed:18650806|doi:10.1038/nature07170|imex:IM-17993 taxid:83334(eco57)|taxid:83334("Escherichia coli O157:H7") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15717684|imex:IM-17993-2|dip:DIP-189577E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR006891(EspF protein)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0009405"(obsolete pathogenesis)|refseq:NP_310742.1|refseq:WP_010917831.1|go:"GO:0005576"(extracellular region)|rcsb pdb:2K42|rcsb pdb:2KXC|rcsb pdb:2LNH|dip:DIP-59949N mint:O08816|rgd:735144|dip:DIP-17016N|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0006900"(vesicle budding from membrane)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0009617"(response to bacterium)|go:"GO:0010324"(membrane invagination)|go:"GO:0016050"(vesicle organization)|go:"GO:0030027"(lamellipodium)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030048"(actin filament-based movement)|go:"GO:0030050"(vesicle transport along actin filament)|go:"GO:0030478"(actin cap)|go:"GO:0031252"(cell leading edge)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0034629"|go:"GO:0042802"(identical protein binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050921"(positive regulation of chemotaxis)|go:"GO:0051301"(cell division)|go:"GO:0051491"(positive regulation of filopodium assembly)|go:"GO:0051653"(spindle localization)|go:"GO:0060491"(regulation of cell projection assembly)|go:"GO:0060997"(dendritic spine morphogenesis)|go:"GO:0097320"(plasma membrane tubulation)|go:"GO:0098794"(postsynapse)|go:"GO:0098974"(postsynaptic actin cytoskeleton organization)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1903526"(negative regulation of membrane tubulation)|go:"GO:2000370"(positive regulation of clathrin-dependent endocytosis)|go:"GO:2000402"(negative regulation of lymphocyte migration)|go:"GO:2000601"(positive regulation of Arp2/3 complex-mediated actin nucleation)|interpro:IPR000095(PAK-box/P21-Rho-binding)|interpro:IPR000697(EVH1)|interpro:IPR003124(Actin-binding WH2)|interpro:IPR011026(Wiscott-Aldrich syndrome, C-terminal)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR030214|interpro:IPR033927|interpro:IPR036936|rcsb pdb:1MKE|rcsb pdb:2IFS|go:"GO:0000139"(Golgi membrane) psi-mi:"MI:0465"(dip) caution:This sequence has been withdrawn from Uniprot. - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/05 2017/08/10 rogid:WARX33S3/G5CXG922GIjofxveNc83334 rogid:lKgHtUQQEc8C14/X9D8WOvry2iM10116 rigid:c0LdFPSux2XWLpoaenuBKr/Ts08 false sufficient binding region:80-126 fluorescein isothiocyanate label:236-236|binding-associated region:226-274 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P0DJ88 uniprotkb:O08816 intact:EBI-10039462|uniprotkb:Q8X2D5|uniprotkb:P0DJ89 intact:EBI-6142604 psi-mi:esfu2_eco57(display_long)|uniprotkb:"espF(U)"(gene name)|psi-mi:"espF(U)"(display_short)|uniprotkb:tccP(gene name synonym)|uniprotkb:EspF-like protein encoded on prophage U(gene name synonym)|uniprotkb:Tir-cytoskeleton coupling protein TccP(gene name synonym)|uniprotkb:ECs2715(locus name) psi-mi:wasl_rat(display_long)|uniprotkb:Wasl(gene name)|psi-mi:Wasl(display_short) psi-mi:"MI:0028"(cosedimentation in solution) Sallee et al. (2008) pubmed:18650806|doi:10.1038/nature07170|imex:IM-17993 taxid:83334(eco57)|taxid:83334("Escherichia coli O157:H7") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15717759|imex:IM-17993-5|dip:DIP-189577E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR006891(EspF protein)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0009405"(obsolete pathogenesis)|refseq:NP_310742.1|refseq:WP_010917831.1|go:"GO:0005576"(extracellular region)|rcsb pdb:2K42|rcsb pdb:2KXC|rcsb pdb:2LNH|dip:DIP-59949N mint:O08816|rgd:735144|dip:DIP-17016N|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0006900"(vesicle budding from membrane)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0009617"(response to bacterium)|go:"GO:0010324"(membrane invagination)|go:"GO:0016050"(vesicle organization)|go:"GO:0030027"(lamellipodium)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030048"(actin filament-based movement)|go:"GO:0030050"(vesicle transport along actin filament)|go:"GO:0030478"(actin cap)|go:"GO:0031252"(cell leading edge)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0034629"|go:"GO:0042802"(identical protein binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050921"(positive regulation of chemotaxis)|go:"GO:0051301"(cell division)|go:"GO:0051491"(positive regulation of filopodium assembly)|go:"GO:0051653"(spindle localization)|go:"GO:0060491"(regulation of cell projection assembly)|go:"GO:0060997"(dendritic spine morphogenesis)|go:"GO:0097320"(plasma membrane tubulation)|go:"GO:0098794"(postsynapse)|go:"GO:0098974"(postsynaptic actin cytoskeleton organization)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1903526"(negative regulation of membrane tubulation)|go:"GO:2000370"(positive regulation of clathrin-dependent endocytosis)|go:"GO:2000402"(negative regulation of lymphocyte migration)|go:"GO:2000601"(positive regulation of Arp2/3 complex-mediated actin nucleation)|interpro:IPR000095(PAK-box/P21-Rho-binding)|interpro:IPR000697(EVH1)|interpro:IPR003124(Actin-binding WH2)|interpro:IPR011026(Wiscott-Aldrich syndrome, C-terminal)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR030214|interpro:IPR033927|interpro:IPR036936|rcsb pdb:1MKE|rcsb pdb:2IFS|go:"GO:0000139"(Golgi membrane) psi-mi:"MI:0465"(dip) caution:This sequence has been withdrawn from Uniprot. - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/05 2017/08/10 rogid:WARX33S3/G5CXG922GIjofxveNc83334 rogid:lKgHtUQQEc8C14/X9D8WOvry2iM10116 rigid:c0LdFPSux2XWLpoaenuBKr/Ts08 false sufficient binding region:80-173 binding-associated region:178-274|binding-associated region:392-501 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)