#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P42225 uniprotkb:P30561 intact:EBI-647118 intact:EBI-78863|uniprotkb:Q8QZX6|uniprotkb:Q8R4S3|uniprotkb:Q99P79|uniprotkb:Q9QVY1 psi-mi:stat1_mouse(display_long)|uniprotkb:Stat1(gene name)|psi-mi:Stat1(display_short) psi-mi:ahr_mouse(display_long)|uniprotkb:Ahr(gene name)|psi-mi:Ahr(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kimura et al. (2008) pubmed:18607004|doi:10.1073/pnas.0804231105|imex:IM-9403 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15714226|imex:IM-9403-1|dip:DIP-87977E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) dip:DIP-38739N|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006952"(defense response)|go:"GO:0007259"(receptor signaling pathway via JAK-STAT)|go:"GO:0007584"(response to nutrient)|go:"GO:0008015"(blood circulation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0009617"(response to bacterium)|go:"GO:0010742"(macrophage derived foam cell differentiation)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019899"(enzyme binding)|go:"GO:0030424"(axon)|go:"GO:0005730"(nucleolus)|reactome:R-MMU-1059683|reactome:R-MMU-1169408|reactome:R-MMU-1433557|reactome:R-MMU-186763|reactome:R-MMU-6785807|reactome:R-MMU-877300|reactome:R-MMU-877312|reactome:R-MMU-8854691|reactome:R-MMU-8984722|reactome:R-MMU-8985947|reactome:R-MMU-9020956|reactome:R-MMU-9020958|reactome:R-MMU-909733|reactome:R-MMU-912694|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001937"(negative regulation of endothelial cell proliferation)|go:"GO:0002053"(positive regulation of mesenchymal cell proliferation)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0003340"(negative regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis)|go:"GO:0003677"(DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0031663"(lipopolysaccharide-mediated signaling pathway)|go:"GO:0031730"(CCR5 chemokine receptor binding)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032727"(positive regulation of interferon-alpha production)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0034097"(response to cytokine)|go:"GO:0034240"(negative regulation of macrophage fusion)|go:"GO:0034340"(response to type I interferon)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0035456"(response to interferon-beta)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042393"(histone binding)|go:"GO:0030425"(dendrite)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043330"(response to exogenous dsRNA)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046725"(negative regulation by virus of viral protein levels in host cell)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0051591"(response to cAMP)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0072136"(metanephric mesenchymal cell proliferation involved in metanephros development)|go:"GO:0072162"(metanephric mesenchymal cell differentiation)|go:"GO:0072308"(negative regulation of metanephric nephron tubule epithelial cell differentiation)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR000980(SH2 motif)|interpro:IPR001217(STAT transcription factor, core)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR012345(STAT transcription factor, DNA-binding, subdomain)|interpro:IPR013799(STAT transcription factor, protein interaction)|interpro:IPR013800(STAT transcription factor, all-alpha)|interpro:IPR013801(STAT transcription factor, DNA-binding)|interpro:IPR015988(STAT transcription factor, coiled coil)|interpro:IPR022752|interpro:IPR035859|interpro:IPR036535|go:"GO:0051607"(defense response to virus)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0051770"(positive regulation of nitric-oxide synthase biosynthetic process)|go:"GO:0060333"(interferon-gamma-mediated signaling pathway)|go:"GO:0060337"(type I interferon signaling pathway)|go:"GO:0061326"(renal tubule development)|interpro:IPR036860|go:"GO:0070106"(interleukin-27-mediated signaling pathway)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071345"(cellular response to cytokine stimulus)|interpro:IPR038295 refseq:NP_038492.1|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001094"(TFIID-class transcription factor complex binding)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0001541"(ovarian follicle development)|go:"GO:0001568"(blood vessel development)|go:"GO:0001569"(branching involved in blood vessel morphogenesis)|go:"GO:0001782"(B cell homeostasis)|go:"GO:0001889"(liver development)|go:"GO:0001922"(B-1 B cell homeostasis)|go:"GO:0001974"(blood vessel remodeling)|go:"GO:0002260"(lymphocyte homeostasis)|go:"GO:0002376"(immune system process)|go:"GO:0002819"(regulation of adaptive immune response)|go:"GO:0002841"(negative regulation of T cell mediated immune response to tumor cell)|go:"GO:0003085"(negative regulation of systemic arterial blood pressure)|go:"GO:0003214"(cardiac left ventricle morphogenesis)|go:"GO:0003243"(circumferential growth involved in left ventricle morphogenesis)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006805"(xenobiotic metabolic process)|go:"GO:0007049"(cell cycle)|go:"GO:0008015"(blood circulation)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0009410"(response to xenobiotic stimulus)|go:"GO:0009636"(response to toxic substance)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010693"(negative regulation of alkaline phosphatase activity)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0015643"(toxic substance binding)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0017162"(aryl hydrocarbon receptor binding)|go:"GO:0019933"(cAMP-mediated signaling)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030850"(prostate gland development)|go:"GO:0030888"(regulation of B cell proliferation)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033689"(negative regulation of osteoblast proliferation)|go:"GO:0034751"(aryl hydrocarbon receptor complex)|go:"GO:0034752"(cytosolic aryl hydrocarbon receptor complex)|go:"GO:0034753"(nuclear aryl hydrocarbon receptor complex)|go:"GO:0035162"(embryonic hemopoiesis)|go:"GO:0035166"(post-embryonic hemopoiesis)|go:"GO:0040010"(positive regulation of growth rate)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043029"(T cell homeostasis)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045668"(negative regulation of osteoblast differentiation)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0045906"(negative regulation of vasoconstriction)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048514"(blood vessel morphogenesis)|go:"GO:0048536"(spleen development)|go:"GO:0048608"(reproductive structure development)|go:"GO:0048732"(gland development)|go:"GO:0048745"(smooth muscle tissue development)|go:"GO:0051087"(chaperone binding)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0060420"(regulation of heart growth)|go:"GO:0060547"(negative regulation of necrotic cell death)|go:"GO:0060841"(venous blood vessel development)|go:"GO:0060993"(kidney morphogenesis)|go:"GO:0061009"(common bile duct development)|go:"GO:0070888"(E-box binding)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0072102"(glomerulus morphogenesis)|go:"GO:0097746"(blood vessel diameter maintenance)|go:"GO:1903170"(negative regulation of calcium ion transmembrane transport)|go:"GO:1904322"(cellular response to forskolin)|go:"GO:1904613"(cellular response to 2,3,7,8-tetrachlorodibenzodioxine)|go:"GO:1904682"(cellular response to 3-methylcholanthrene)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000279"(negative regulation of DNA biosynthetic process)|interpro:IPR000014(PAS)|interpro:IPR001610(PAC motif)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013655(PAS fold-3)|interpro:IPR013767(PAS fold)|interpro:IPR033348|interpro:IPR035965|interpro:IPR036638|interpro:IPR039091|rcsb pdb:4M4X|rcsb pdb:5V0L|dip:DIP-222N|reactome:R-MMU-211945|reactome:R-MMU-211976|reactome:R-MMU-211981|reactome:R-MMU-8937144 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse)|taxid:10090(Mus musculus) - 2017/08/05 2017/08/10 rogid:0UU+GWFvWO4Uj//otV/IYgwShKg10090 rogid:N+pBJ492yievt6CTflKb8oQgqfU10090 rigid:y0KCH++PN9tV01S5qQl98IcMfds false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot)