#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q9JJV9	uniprotkb:Q9Z0J4	intact:EBI-8313814|ensembl:ENSMUSP00000113272|intact:MINT-4130032|uniprotkb:Q3UH91|uniprotkb:E9Q1D2|intact:UNK-5412858	intact:EBI-397596|uniprotkb:Q64208|uniprotkb:Q3UR10|ensembl:ENSMUSP00000120421|ensembl:ENSMUSP00000127432	psi-mi:scn5a_mouse(display_long)|uniprotkb:Scn5a(gene name)|psi-mi:Scn5a(display_short)|uniprotkb:Sodium channel protein type V subunit alpha(gene name synonym)|uniprotkb:Voltage-gated sodium channel subunit alpha Nav1.5(gene name synonym)|uniprotkb:Sodium channel protein cardiac muscle subunit alpha(gene name synonym)|uniprotkb:mH1(gene name synonym)	psi-mi:nos1_mouse(display_long)|uniprotkb:Nos1(gene name)|psi-mi:Nos1(display_short)|uniprotkb:bNOS(gene name synonym)|uniprotkb:NOS type I(gene name synonym)|uniprotkb:Neuronal NOS(gene name synonym)|uniprotkb:Constitutive NOS(gene name synonym)|uniprotkb:NC-NOS(gene name synonym)|uniprotkb:Peptidyl-cysteine S-nitrosylase NOS1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Ueda et al. (2008)	pubmed:18591664|doi:10.1073/pnas.0801294105|imex:IM-9394	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15712165|imex:IM-9394-1|dip:DIP-87964E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000032511(gene)|ensembl:ENSMUST00000120420(transcript)|go:"GO:0001518"(voltage-gated sodium channel complex)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0003231"(cardiac ventricle development)|go:"GO:0005244"(voltage-gated ion channel activity)|go:"GO:0005248"(voltage-gated sodium channel activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005901"(caveola)|go:"GO:0006814"(sodium ion transport)|go:"GO:0009986"(cell surface)|go:"GO:0010460"(positive regulation of heart rate)|go:"GO:0010765"(positive regulation of sodium ion transport)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0014704"(intercalated disc)|go:"GO:0014894"(response to denervation involved in regulation of muscle adaptation)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0017134"(fibroblast growth factor binding)|go:"GO:0019228"(neuronal action potential)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030018"(Z disc)|go:"GO:0030315"(T-tubule)|go:"GO:0030506"(ankyrin binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034706"(sodium channel complex)|go:"GO:0035725"(sodium ion transmembrane transport)|go:"GO:0042383"(sarcolemma)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045760"(positive regulation of action potential)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051899"(membrane depolarization)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060371"(regulation of atrial cardiac muscle cell membrane depolarization)|go:"GO:0060372"(regulation of atrial cardiac muscle cell membrane repolarization)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:0086002"(cardiac muscle cell action potential involved in contraction)|go:"GO:0086004"(regulation of cardiac muscle cell contraction)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0086006"(voltage-gated sodium channel activity involved in cardiac muscle cell action potential)|go:"GO:0086010"(membrane depolarization during action potential)|go:"GO:0086012"(membrane depolarization during cardiac muscle cell action potential)|go:"GO:0086014"(atrial cardiac muscle cell action potential)|go:"GO:0086015"(SA node cell action potential)|go:"GO:0086016"(AV node cell action potential)|go:"GO:0086043"(bundle of His cell action potential)|go:"GO:0086045"(membrane depolarization during AV node cell action potential)|go:"GO:0005886"(plasma membrane)|go:"GO:0086046"(membrane depolarization during SA node cell action potential)|go:"GO:0086047"(membrane depolarization during Purkinje myocyte cell action potential)|go:"GO:0086048"(membrane depolarization during bundle of His cell action potential)|go:"GO:0086060"(voltage-gated sodium channel activity involved in AV node cell action potential)|go:"GO:0086061"(voltage-gated sodium channel activity involved in bundle of His cell action potential)|go:"GO:0086062"(voltage-gated sodium channel activity involved in Purkinje myocyte action potential)|go:"GO:0086063"(voltage-gated sodium channel activity involved in SA node cell action potential)|go:"GO:0086067"(AV node cell to bundle of His cell communication)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098719"(sodium ion import across plasma membrane)|go:"GO:0098912"(membrane depolarization during atrial cardiac muscle cell action potential)|go:"GO:1902305"(regulation of sodium ion transmembrane transport)|interpro:IPR001696(Na+ channel)|interpro:IPR005821(Ion transport)|interpro:IPR008053(Na+ channel 5)|interpro:IPR010526(Sodium ion transport-associated)|interpro:IPR024583|interpro:IPR027359|interpro:IPR043203|interpro:IPR044564|mint:Q9JJV9|reactome:R-MMU-5576892|refseq:NP_067519.2|refseq:NP_001240789.1|dip:DIP-46142N	refseq:NP_032738.1|refseq:XP_017176196.1|dip:DIP-31556N|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0071872"(cellular response to epinephrine stimulus)|go:"GO:0071944"(cell periphery)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098735"(positive regulation of the force of heart contraction)|go:"GO:0098924"(retrograde trans-synaptic signaling by nitric oxide)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099091"(postsynaptic specialization, intracellular component)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:0099163"(synaptic signaling by nitric oxide)|go:"GO:0140196"(positive regulation of adenylate cyclase-activating adrenergic receptor signaling pathway involved in heart process)|go:"GO:1900273"(positive regulation of long-term synaptic potentiation)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1902307"(positive regulation of sodium ion transmembrane transport)|go:"GO:0070402"(NADPH binding)|go:"GO:0033017"(sarcoplasmic reticulum membrane)|go:"GO:0033137"(negative regulation of peptidyl-serine phosphorylation)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033555"(multicellular organismal response to stress)|go:"GO:0034760"(negative regulation of iron ion transmembrane transport)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0042311"(vasodilation)|go:"GO:0042383"(sarcolemma)|go:"GO:0042582"(azurophil granule)|go:"GO:0042738"|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043197"(dendritic spine)|go:"GO:0043267"(negative regulation of potassium ion transport)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043627"(response to estrogen)|go:"GO:0044305"(calyx of Held)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045202"(synapse)|go:"GO:0045776"(negative regulation of blood pressure)|go:"GO:0045822"(negative regulation of heart contraction)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045906"(negative regulation of vasoconstriction)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0046870"(cadmium ion binding)|go:"GO:0048148"(behavioral response to cocaine)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050660"(flavin adenine dinucleotide binding)|go:"GO:0050661"(NADP binding)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0051117"(ATPase binding)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0051346"(negative regulation of hydrolase activity)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051612"(negative regulation of serotonin uptake)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0051930"(regulation of sensory perception of pain)|go:"GO:0061875"(negative regulation of hepatic stellate cell contraction)|go:"GO:0032991"(protein-containing complex)|interpro:IPR001433("Oxidoreductase FAD/NAD(P)-binding")|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001709(Flavoprotein pyridine nucleotide cytochrome reductase)|interpro:IPR003097(FAD-binding, type 1)|interpro:IPR004030(Nitric oxide synthase, oxygenase region)|interpro:IPR008254(Flavodoxin/nitric oxide synthase)|interpro:IPR012144(Nitric-oxide synthase)|interpro:IPR017927|interpro:IPR017938|interpro:IPR023173|interpro:IPR029039|interpro:IPR036034|interpro:IPR036119|interpro:IPR001094(Flavodoxin-like)|interpro:IPR039261|rcsb pdb:2O60|reactome:R-MMU-1222556|reactome:R-MMU-392154|reactome:R-MMU-5578775|ensembl:ENSMUSG00000029361(gene)|ensembl:ENSMUST00000142742(transcript)|ensembl:ENSMUST00000171055(transcript)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0002028"(regulation of sodium ion transport)|go:"GO:0004517"(nitric-oxide synthase activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006527"(arginine catabolic process)|go:"GO:0006809"(nitric oxide biosynthetic process)|go:"GO:0006936"(muscle contraction)|go:"GO:0006941"(striated muscle contraction)|go:"GO:0007263"(nitric oxide mediated signal transduction)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009408"(response to heat)|go:"GO:0009725"(response to hormone)|go:"GO:0010181"(FMN binding)|go:"GO:0012506"(vesicle membrane)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0016709"("oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen")|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0018119"(peptidyl-cysteine S-nitrosylation)|go:"GO:0019899"(enzyme binding)|go:"GO:0020037"(heme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030141"(secretory granule)|go:"GO:0030315"(T-tubule)|go:"GO:0030425"(dendrite)|go:"GO:0031284"(positive regulation of guanylate cyclase activity)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032496"(response to lipopolysaccharide)	psi-mi:"MI:0465"(dip)	caution:This sequence has been withdrawn from Uniprot.|crc64:5A3BC3C191859E79|comment:mint	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse)|taxid:10090(Mus musculus)	-	2017/08/05	2017/08/10	rogid:EMw8Sy0lXX45svkE1xgL8sQYG/E10090	rogid:BuPBvQk0jEhDNZNi82D3OidmYwE10090	rigid:jQQFAUqGde98HJ6r9GKlhK644nY	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9JJV9	uniprotkb:Q6Q477	intact:EBI-8313814|ensembl:ENSMUSP00000113272|intact:MINT-4130032|uniprotkb:Q3UH91|uniprotkb:E9Q1D2|intact:UNK-5412858	intact:EBI-2308323|uniprotkb:Q32ME1|ensembl:ENSMUSP00000119242|ensembl:ENSMUSP00000133187	psi-mi:scn5a_mouse(display_long)|uniprotkb:Scn5a(gene name)|psi-mi:Scn5a(display_short)|uniprotkb:Sodium channel protein type V subunit alpha(gene name synonym)|uniprotkb:Voltage-gated sodium channel subunit alpha Nav1.5(gene name synonym)|uniprotkb:Sodium channel protein cardiac muscle subunit alpha(gene name synonym)|uniprotkb:mH1(gene name synonym)	psi-mi:at2b4_mouse(display_long)|uniprotkb:Atp2b4(gene name)|psi-mi:Atp2b4(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Ueda et al. (2008)	pubmed:18591664|doi:10.1073/pnas.0801294105|imex:IM-9394	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15712165|imex:IM-9394-1|dip:DIP-87964E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000032511(gene)|ensembl:ENSMUST00000120420(transcript)|go:"GO:0001518"(voltage-gated sodium channel complex)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0003231"(cardiac ventricle development)|go:"GO:0005244"(voltage-gated ion channel activity)|go:"GO:0005248"(voltage-gated sodium channel activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005901"(caveola)|go:"GO:0006814"(sodium ion transport)|go:"GO:0009986"(cell surface)|go:"GO:0010460"(positive regulation of heart rate)|go:"GO:0010765"(positive regulation of sodium ion transport)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0014704"(intercalated disc)|go:"GO:0014894"(response to denervation involved in regulation of muscle adaptation)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0017134"(fibroblast growth factor binding)|go:"GO:0019228"(neuronal action potential)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030018"(Z disc)|go:"GO:0030315"(T-tubule)|go:"GO:0030506"(ankyrin binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034706"(sodium channel complex)|go:"GO:0035725"(sodium ion transmembrane transport)|go:"GO:0042383"(sarcolemma)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045760"(positive regulation of action potential)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051899"(membrane depolarization)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060371"(regulation of atrial cardiac muscle cell membrane depolarization)|go:"GO:0060372"(regulation of atrial cardiac muscle cell membrane repolarization)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:0086002"(cardiac muscle cell action potential involved in contraction)|go:"GO:0086004"(regulation of cardiac muscle cell contraction)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0086006"(voltage-gated sodium channel activity involved in cardiac muscle cell action potential)|go:"GO:0086010"(membrane depolarization during action potential)|go:"GO:0086012"(membrane depolarization during cardiac muscle cell action potential)|go:"GO:0086014"(atrial cardiac muscle cell action potential)|go:"GO:0086015"(SA node cell action potential)|go:"GO:0086016"(AV node cell action potential)|go:"GO:0086043"(bundle of His cell action potential)|go:"GO:0086045"(membrane depolarization during AV node cell action potential)|go:"GO:0005886"(plasma membrane)|go:"GO:0086046"(membrane depolarization during SA node cell action potential)|go:"GO:0086047"(membrane depolarization during Purkinje myocyte cell action potential)|go:"GO:0086048"(membrane depolarization during bundle of His cell action potential)|go:"GO:0086060"(voltage-gated sodium channel activity involved in AV node cell action potential)|go:"GO:0086061"(voltage-gated sodium channel activity involved in bundle of His cell action potential)|go:"GO:0086062"(voltage-gated sodium channel activity involved in Purkinje myocyte action potential)|go:"GO:0086063"(voltage-gated sodium channel activity involved in SA node cell action potential)|go:"GO:0086067"(AV node cell to bundle of His cell communication)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098719"(sodium ion import across plasma membrane)|go:"GO:0098912"(membrane depolarization during atrial cardiac muscle cell action potential)|go:"GO:1902305"(regulation of sodium ion transmembrane transport)|interpro:IPR001696(Na+ channel)|interpro:IPR005821(Ion transport)|interpro:IPR008053(Na+ channel 5)|interpro:IPR010526(Sodium ion transport-associated)|interpro:IPR024583|interpro:IPR027359|interpro:IPR043203|interpro:IPR044564|mint:Q9JJV9|reactome:R-MMU-5576892|refseq:NP_067519.2|refseq:NP_001240789.1|dip:DIP-46142N	refseq:NP_998781.1|refseq:NP_001161421.1|refseq:XP_006529786.1|refseq:XP_006529787.1|refseq:XP_006529788.1|dip:DIP-46143N|ensembl:ENSMUSG00000026463(gene)|ensembl:ENSMUST00000143567(transcript)|ensembl:ENSMUST00000165602(transcript)|go:"GO:0003407"(neural retina development)|go:"GO:0005388"(P-type calcium transporter activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0007283"(spermatogenesis)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010751"(negative regulation of nitric oxide mediated signal transduction)|go:"GO:0014832"(urinary bladder smooth muscle contraction)|go:"GO:0015085"(calcium ion transmembrane transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0019829"(ATPase-coupled cation transmembrane transporter activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0021766"(hippocampus development)|go:"GO:0030018"(Z disc)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030315"(T-tubule)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030346"(protein phosphatase 2B binding)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0036126"(sperm flagellum)|go:"GO:0036487"(nitric-oxide synthase inhibitor activity)|go:"GO:0042383"(sarcolemma)|go:"GO:0043005"(neuron projection)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043537"(negative regulation of blood vessel endothelial cell migration)|go:"GO:0045019"(negative regulation of nitric oxide biosynthetic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051599"(response to hydrostatic pressure)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0070885"(negative regulation of calcineurin-NFAT signaling cascade)|go:"GO:0071872"(cellular response to epinephrine stimulus)|go:"GO:0097228"(sperm principal piece)|go:"GO:0098736"(negative regulation of the force of heart contraction)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099059"(integral component of presynaptic active zone membrane)|go:"GO:0140199"(negative regulation of adenylate cyclase-activating adrenergic receptor signaling pathway involved in heart process)|go:"GO:1900082"(negative regulation of arginine catabolic process)|go:"GO:1901660"(calcium ion export)|go:"GO:1902548"(negative regulation of cellular response to vascular endothelial growth factor stimulus)|go:"GO:1902806"(regulation of cell cycle G1/S phase transition)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1903243"(negative regulation of cardiac muscle hypertrophy in response to stress)|go:"GO:1903249"(negative regulation of citrulline biosynthetic process)|go:"GO:1905145"(cellular response to acetylcholine)|go:"GO:2000481"(positive regulation of cAMP-dependent protein kinase activity)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|interpro:IPR004014(ATPase, P-type cation-transporter, N-terminal)|interpro:IPR006068(ATPase, P-type cation-transporter, C-terminal)|interpro:IPR006408(Calcium-translocating P-type ATPase, PMCA-type)|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR018303|interpro:IPR022141|interpro:IPR023214|interpro:IPR023298|interpro:IPR023299|interpro:IPR036412|interpro:IPR044492|reactome:R-MMU-418359|reactome:R-MMU-5578775|reactome:R-MMU-936837	psi-mi:"MI:0465"(dip)	caution:This sequence has been withdrawn from Uniprot.|crc64:5A3BC3C191859E79|comment:mint	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse)|taxid:10090(Mus musculus)	-	2017/08/05	2017/08/10	rogid:EMw8Sy0lXX45svkE1xgL8sQYG/E10090	rogid:IV80bQo2/6AW0+lxIhWZcRIFXBE10090	rigid:jQQFAUqGde98HJ6r9GKlhK644nY	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9JJV9	uniprotkb:Q61234	intact:EBI-8313814|ensembl:ENSMUSP00000113272|intact:MINT-4130032|uniprotkb:Q3UH91|uniprotkb:E9Q1D2|intact:UNK-5412858	intact:EBI-295952|uniprotkb:Q8VEF3|ensembl:ENSMUSP00000028991	psi-mi:scn5a_mouse(display_long)|uniprotkb:Scn5a(gene name)|psi-mi:Scn5a(display_short)|uniprotkb:Sodium channel protein type V subunit alpha(gene name synonym)|uniprotkb:Voltage-gated sodium channel subunit alpha Nav1.5(gene name synonym)|uniprotkb:Sodium channel protein cardiac muscle subunit alpha(gene name synonym)|uniprotkb:mH1(gene name synonym)	psi-mi:snta1_mouse(display_long)|uniprotkb:Snta1(gene name)|psi-mi:Snta1(display_short)|uniprotkb:Snt1(gene name synonym)|uniprotkb:59 kDa dystrophin-associated protein A1 acidic component 1(gene name synonym)|uniprotkb:Syntrophin-1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Ueda et al. (2008)	pubmed:18591664|doi:10.1073/pnas.0801294105|imex:IM-9394	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15712165|imex:IM-9394-1|dip:DIP-87964E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000032511(gene)|ensembl:ENSMUST00000120420(transcript)|go:"GO:0001518"(voltage-gated sodium channel complex)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0003231"(cardiac ventricle development)|go:"GO:0005244"(voltage-gated ion channel activity)|go:"GO:0005248"(voltage-gated sodium channel activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005901"(caveola)|go:"GO:0006814"(sodium ion transport)|go:"GO:0009986"(cell surface)|go:"GO:0010460"(positive regulation of heart rate)|go:"GO:0010765"(positive regulation of sodium ion transport)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0014704"(intercalated disc)|go:"GO:0014894"(response to denervation involved in regulation of muscle adaptation)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0017134"(fibroblast growth factor binding)|go:"GO:0019228"(neuronal action potential)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030018"(Z disc)|go:"GO:0030315"(T-tubule)|go:"GO:0030506"(ankyrin binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034706"(sodium channel complex)|go:"GO:0035725"(sodium ion transmembrane transport)|go:"GO:0042383"(sarcolemma)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045760"(positive regulation of action potential)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051899"(membrane depolarization)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060371"(regulation of atrial cardiac muscle cell membrane depolarization)|go:"GO:0060372"(regulation of atrial cardiac muscle cell membrane repolarization)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:0086002"(cardiac muscle cell action potential involved in contraction)|go:"GO:0086004"(regulation of cardiac muscle cell contraction)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0086006"(voltage-gated sodium channel activity involved in cardiac muscle cell action potential)|go:"GO:0086010"(membrane depolarization during action potential)|go:"GO:0086012"(membrane depolarization during cardiac muscle cell action potential)|go:"GO:0086014"(atrial cardiac muscle cell action potential)|go:"GO:0086015"(SA node cell action potential)|go:"GO:0086016"(AV node cell action potential)|go:"GO:0086043"(bundle of His cell action potential)|go:"GO:0086045"(membrane depolarization during AV node cell action potential)|go:"GO:0005886"(plasma membrane)|go:"GO:0086046"(membrane depolarization during SA node cell action potential)|go:"GO:0086047"(membrane depolarization during Purkinje myocyte cell action potential)|go:"GO:0086048"(membrane depolarization during bundle of His cell action potential)|go:"GO:0086060"(voltage-gated sodium channel activity involved in AV node cell action potential)|go:"GO:0086061"(voltage-gated sodium channel activity involved in bundle of His cell action potential)|go:"GO:0086062"(voltage-gated sodium channel activity involved in Purkinje myocyte action potential)|go:"GO:0086063"(voltage-gated sodium channel activity involved in SA node cell action potential)|go:"GO:0086067"(AV node cell to bundle of His cell communication)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098719"(sodium ion import across plasma membrane)|go:"GO:0098912"(membrane depolarization during atrial cardiac muscle cell action potential)|go:"GO:1902305"(regulation of sodium ion transmembrane transport)|interpro:IPR001696(Na+ channel)|interpro:IPR005821(Ion transport)|interpro:IPR008053(Na+ channel 5)|interpro:IPR010526(Sodium ion transport-associated)|interpro:IPR024583|interpro:IPR027359|interpro:IPR043203|interpro:IPR044564|mint:Q9JJV9|reactome:R-MMU-5576892|refseq:NP_067519.2|refseq:NP_001240789.1|dip:DIP-46142N	go:"GO:0045211"(postsynaptic membrane)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0051117"(ATPase binding)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:1902083"(negative regulation of peptidyl-cysteine S-nitrosylation)|go:"GO:1902305"(regulation of sodium ion transmembrane transport)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015482(Syntrophin)|interpro:IPR028552|interpro:IPR036034|interpro:IPR041428|mint:Q61234|rcsb pdb:1QAV|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0031594"(neuromuscular junction)|rcsb pdb:1Z86|rcsb pdb:1Z87|rcsb pdb:2ADZ|go:"GO:0032991"(protein-containing complex)|go:"GO:0042383"(sarcolemma)|rcsb pdb:2PDZ|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045202"(synapse)|rcsb pdb:4HOP|ensembl:ENSMUSG00000027488(gene)|ensembl:ENSMUST00000028991(transcript)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0003117"(regulation of vasoconstriction by circulating norepinephrine)|go:"GO:0003779"(actin binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005516"(calmodulin binding)|dip:DIP-32898N	psi-mi:"MI:0465"(dip)	caution:This sequence has been withdrawn from Uniprot.|crc64:5A3BC3C191859E79|comment:mint	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse)|taxid:10090(Mus musculus)	-	2017/08/05	2017/08/10	rogid:EMw8Sy0lXX45svkE1xgL8sQYG/E10090	rogid:ENtty34uPh1ZGRmhT4TTIM/OVpI10090	rigid:jQQFAUqGde98HJ6r9GKlhK644nY	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9JJV9	uniprotkb:Q6Q477	intact:EBI-8313814|ensembl:ENSMUSP00000113272|intact:MINT-4130032|uniprotkb:Q3UH91|uniprotkb:E9Q1D2|intact:UNK-5412858	intact:EBI-2308323|uniprotkb:Q32ME1|ensembl:ENSMUSP00000119242|ensembl:ENSMUSP00000133187	psi-mi:scn5a_mouse(display_long)|uniprotkb:Scn5a(gene name)|psi-mi:Scn5a(display_short)|uniprotkb:Sodium channel protein type V subunit alpha(gene name synonym)|uniprotkb:Voltage-gated sodium channel subunit alpha Nav1.5(gene name synonym)|uniprotkb:Sodium channel protein cardiac muscle subunit alpha(gene name synonym)|uniprotkb:mH1(gene name synonym)	psi-mi:at2b4_mouse(display_long)|uniprotkb:Atp2b4(gene name)|psi-mi:Atp2b4(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Ueda et al. (2008)	pubmed:18591664|doi:10.1073/pnas.0801294105|imex:IM-9394	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15712220|imex:IM-9394-3|dip:DIP-87965E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000032511(gene)|ensembl:ENSMUST00000120420(transcript)|go:"GO:0001518"(voltage-gated sodium channel complex)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0003231"(cardiac ventricle development)|go:"GO:0005244"(voltage-gated ion channel activity)|go:"GO:0005248"(voltage-gated sodium channel activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005901"(caveola)|go:"GO:0006814"(sodium ion transport)|go:"GO:0009986"(cell surface)|go:"GO:0010460"(positive regulation of heart rate)|go:"GO:0010765"(positive regulation of sodium ion transport)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0014704"(intercalated disc)|go:"GO:0014894"(response to denervation involved in regulation of muscle adaptation)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0017134"(fibroblast growth factor binding)|go:"GO:0019228"(neuronal action potential)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030018"(Z disc)|go:"GO:0030315"(T-tubule)|go:"GO:0030506"(ankyrin binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034706"(sodium channel complex)|go:"GO:0035725"(sodium ion transmembrane transport)|go:"GO:0042383"(sarcolemma)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045760"(positive regulation of action potential)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051899"(membrane depolarization)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060371"(regulation of atrial cardiac muscle cell membrane depolarization)|go:"GO:0060372"(regulation of atrial cardiac muscle cell membrane repolarization)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:0086002"(cardiac muscle cell action potential involved in contraction)|go:"GO:0086004"(regulation of cardiac muscle cell contraction)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0086006"(voltage-gated sodium channel activity involved in cardiac muscle cell action potential)|go:"GO:0086010"(membrane depolarization during action potential)|go:"GO:0086012"(membrane depolarization during cardiac muscle cell action potential)|go:"GO:0086014"(atrial cardiac muscle cell action potential)|go:"GO:0086015"(SA node cell action potential)|go:"GO:0086016"(AV node cell action potential)|go:"GO:0086043"(bundle of His cell action potential)|go:"GO:0086045"(membrane depolarization during AV node cell action potential)|go:"GO:0005886"(plasma membrane)|go:"GO:0086046"(membrane depolarization during SA node cell action potential)|go:"GO:0086047"(membrane depolarization during Purkinje myocyte cell action potential)|go:"GO:0086048"(membrane depolarization during bundle of His cell action potential)|go:"GO:0086060"(voltage-gated sodium channel activity involved in AV node cell action potential)|go:"GO:0086061"(voltage-gated sodium channel activity involved in bundle of His cell action potential)|go:"GO:0086062"(voltage-gated sodium channel activity involved in Purkinje myocyte action potential)|go:"GO:0086063"(voltage-gated sodium channel activity involved in SA node cell action potential)|go:"GO:0086067"(AV node cell to bundle of His cell communication)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098719"(sodium ion import across plasma membrane)|go:"GO:0098912"(membrane depolarization during atrial cardiac muscle cell action potential)|go:"GO:1902305"(regulation of sodium ion transmembrane transport)|interpro:IPR001696(Na+ channel)|interpro:IPR005821(Ion transport)|interpro:IPR008053(Na+ channel 5)|interpro:IPR010526(Sodium ion transport-associated)|interpro:IPR024583|interpro:IPR027359|interpro:IPR043203|interpro:IPR044564|mint:Q9JJV9|reactome:R-MMU-5576892|refseq:NP_067519.2|refseq:NP_001240789.1|dip:DIP-46142N	refseq:NP_998781.1|refseq:NP_001161421.1|refseq:XP_006529786.1|refseq:XP_006529787.1|refseq:XP_006529788.1|dip:DIP-46143N|ensembl:ENSMUSG00000026463(gene)|ensembl:ENSMUST00000143567(transcript)|ensembl:ENSMUST00000165602(transcript)|go:"GO:0003407"(neural retina development)|go:"GO:0005388"(P-type calcium transporter activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0007283"(spermatogenesis)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010751"(negative regulation of nitric oxide mediated signal transduction)|go:"GO:0014832"(urinary bladder smooth muscle contraction)|go:"GO:0015085"(calcium ion transmembrane transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0019829"(ATPase-coupled cation transmembrane transporter activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0021766"(hippocampus development)|go:"GO:0030018"(Z disc)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030315"(T-tubule)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030346"(protein phosphatase 2B binding)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0036126"(sperm flagellum)|go:"GO:0036487"(nitric-oxide synthase inhibitor activity)|go:"GO:0042383"(sarcolemma)|go:"GO:0043005"(neuron projection)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043537"(negative regulation of blood vessel endothelial cell migration)|go:"GO:0045019"(negative regulation of nitric oxide biosynthetic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051599"(response to hydrostatic pressure)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0070885"(negative regulation of calcineurin-NFAT signaling cascade)|go:"GO:0071872"(cellular response to epinephrine stimulus)|go:"GO:0097228"(sperm principal piece)|go:"GO:0098736"(negative regulation of the force of heart contraction)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099059"(integral component of presynaptic active zone membrane)|go:"GO:0140199"(negative regulation of adenylate cyclase-activating adrenergic receptor signaling pathway involved in heart process)|go:"GO:1900082"(negative regulation of arginine catabolic process)|go:"GO:1901660"(calcium ion export)|go:"GO:1902548"(negative regulation of cellular response to vascular endothelial growth factor stimulus)|go:"GO:1902806"(regulation of cell cycle G1/S phase transition)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1903243"(negative regulation of cardiac muscle hypertrophy in response to stress)|go:"GO:1903249"(negative regulation of citrulline biosynthetic process)|go:"GO:1905145"(cellular response to acetylcholine)|go:"GO:2000481"(positive regulation of cAMP-dependent protein kinase activity)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|interpro:IPR004014(ATPase, P-type cation-transporter, N-terminal)|interpro:IPR006068(ATPase, P-type cation-transporter, C-terminal)|interpro:IPR006408(Calcium-translocating P-type ATPase, PMCA-type)|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR018303|interpro:IPR022141|interpro:IPR023214|interpro:IPR023298|interpro:IPR023299|interpro:IPR036412|interpro:IPR044492|reactome:R-MMU-418359|reactome:R-MMU-5578775|reactome:R-MMU-936837	psi-mi:"MI:0465"(dip)	caution:This sequence has been withdrawn from Uniprot.|crc64:5A3BC3C191859E79|comment:mint	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse)|taxid:10090(Mus musculus)	-	2017/08/05	2017/08/10	rogid:EMw8Sy0lXX45svkE1xgL8sQYG/E10090	rogid:IV80bQo2/6AW0+lxIhWZcRIFXBE10090	rigid:zbI7bMUxigcy04gbHfHTitHc7wE	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9JJV9	uniprotkb:Q61234	intact:EBI-8313814|ensembl:ENSMUSP00000113272|intact:MINT-4130032|uniprotkb:Q3UH91|uniprotkb:E9Q1D2|intact:UNK-5412858	intact:EBI-295952|uniprotkb:Q8VEF3|ensembl:ENSMUSP00000028991	psi-mi:scn5a_mouse(display_long)|uniprotkb:Scn5a(gene name)|psi-mi:Scn5a(display_short)|uniprotkb:Sodium channel protein type V subunit alpha(gene name synonym)|uniprotkb:Voltage-gated sodium channel subunit alpha Nav1.5(gene name synonym)|uniprotkb:Sodium channel protein cardiac muscle subunit alpha(gene name synonym)|uniprotkb:mH1(gene name synonym)	psi-mi:snta1_mouse(display_long)|uniprotkb:Snta1(gene name)|psi-mi:Snta1(display_short)|uniprotkb:Snt1(gene name synonym)|uniprotkb:59 kDa dystrophin-associated protein A1 acidic component 1(gene name synonym)|uniprotkb:Syntrophin-1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Ueda et al. (2008)	pubmed:18591664|doi:10.1073/pnas.0801294105|imex:IM-9394	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15712220|imex:IM-9394-3|dip:DIP-87965E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000032511(gene)|ensembl:ENSMUST00000120420(transcript)|go:"GO:0001518"(voltage-gated sodium channel complex)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0003231"(cardiac ventricle development)|go:"GO:0005244"(voltage-gated ion channel activity)|go:"GO:0005248"(voltage-gated sodium channel activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005901"(caveola)|go:"GO:0006814"(sodium ion transport)|go:"GO:0009986"(cell surface)|go:"GO:0010460"(positive regulation of heart rate)|go:"GO:0010765"(positive regulation of sodium ion transport)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0014704"(intercalated disc)|go:"GO:0014894"(response to denervation involved in regulation of muscle adaptation)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0017134"(fibroblast growth factor binding)|go:"GO:0019228"(neuronal action potential)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030018"(Z disc)|go:"GO:0030315"(T-tubule)|go:"GO:0030506"(ankyrin binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034706"(sodium channel complex)|go:"GO:0035725"(sodium ion transmembrane transport)|go:"GO:0042383"(sarcolemma)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045760"(positive regulation of action potential)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051899"(membrane depolarization)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060371"(regulation of atrial cardiac muscle cell membrane depolarization)|go:"GO:0060372"(regulation of atrial cardiac muscle cell membrane repolarization)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:0086002"(cardiac muscle cell action potential involved in contraction)|go:"GO:0086004"(regulation of cardiac muscle cell contraction)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0086006"(voltage-gated sodium channel activity involved in cardiac muscle cell action potential)|go:"GO:0086010"(membrane depolarization during action potential)|go:"GO:0086012"(membrane depolarization during cardiac muscle cell action potential)|go:"GO:0086014"(atrial cardiac muscle cell action potential)|go:"GO:0086015"(SA node cell action potential)|go:"GO:0086016"(AV node cell action potential)|go:"GO:0086043"(bundle of His cell action potential)|go:"GO:0086045"(membrane depolarization during AV node cell action potential)|go:"GO:0005886"(plasma membrane)|go:"GO:0086046"(membrane depolarization during SA node cell action potential)|go:"GO:0086047"(membrane depolarization during Purkinje myocyte cell action potential)|go:"GO:0086048"(membrane depolarization during bundle of His cell action potential)|go:"GO:0086060"(voltage-gated sodium channel activity involved in AV node cell action potential)|go:"GO:0086061"(voltage-gated sodium channel activity involved in bundle of His cell action potential)|go:"GO:0086062"(voltage-gated sodium channel activity involved in Purkinje myocyte action potential)|go:"GO:0086063"(voltage-gated sodium channel activity involved in SA node cell action potential)|go:"GO:0086067"(AV node cell to bundle of His cell communication)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098719"(sodium ion import across plasma membrane)|go:"GO:0098912"(membrane depolarization during atrial cardiac muscle cell action potential)|go:"GO:1902305"(regulation of sodium ion transmembrane transport)|interpro:IPR001696(Na+ channel)|interpro:IPR005821(Ion transport)|interpro:IPR008053(Na+ channel 5)|interpro:IPR010526(Sodium ion transport-associated)|interpro:IPR024583|interpro:IPR027359|interpro:IPR043203|interpro:IPR044564|mint:Q9JJV9|reactome:R-MMU-5576892|refseq:NP_067519.2|refseq:NP_001240789.1|dip:DIP-46142N	go:"GO:0045211"(postsynaptic membrane)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0051117"(ATPase binding)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:1902083"(negative regulation of peptidyl-cysteine S-nitrosylation)|go:"GO:1902305"(regulation of sodium ion transmembrane transport)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015482(Syntrophin)|interpro:IPR028552|interpro:IPR036034|interpro:IPR041428|mint:Q61234|rcsb pdb:1QAV|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0031594"(neuromuscular junction)|rcsb pdb:1Z86|rcsb pdb:1Z87|rcsb pdb:2ADZ|go:"GO:0032991"(protein-containing complex)|go:"GO:0042383"(sarcolemma)|rcsb pdb:2PDZ|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045202"(synapse)|rcsb pdb:4HOP|ensembl:ENSMUSG00000027488(gene)|ensembl:ENSMUST00000028991(transcript)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0003117"(regulation of vasoconstriction by circulating norepinephrine)|go:"GO:0003779"(actin binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005516"(calmodulin binding)|dip:DIP-32898N	psi-mi:"MI:0465"(dip)	caution:This sequence has been withdrawn from Uniprot.|crc64:5A3BC3C191859E79|comment:mint	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse)|taxid:10090(Mus musculus)	-	2017/08/05	2017/08/10	rogid:EMw8Sy0lXX45svkE1xgL8sQYG/E10090	rogid:ENtty34uPh1ZGRmhT4TTIM/OVpI10090	rigid:zbI7bMUxigcy04gbHfHTitHc7wE	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q14524	uniprotkb:Q13424	intact:EBI-726858|uniprotkb:Q59H93|uniprotkb:E9PEF3|uniprotkb:A5H1P8|uniprotkb:A6N922|uniprotkb:A6N923|uniprotkb:B2RTU0|uniprotkb:Q75RX9|uniprotkb:Q75RY0|uniprotkb:Q86UR3|uniprotkb:Q8IZC9|uniprotkb:Q96J69|uniprotkb:E9PEK2|uniprotkb:E9PFW7|uniprotkb:E7ET19|intact:EBI-28981518|ensembl:ENSP00000328968	intact:EBI-717191|intact:EBI-28985258|ensembl:ENSP00000217381|uniprotkb:Q16438|uniprotkb:A8K7H9|uniprotkb:E1P5N1|uniprotkb:B4DX40	psi-mi:scn5a_human(display_long)|uniprotkb:Sodium channel protein type V subunit alpha(gene name synonym)|uniprotkb:Voltage-gated sodium channel subunit alpha Nav1.5(gene name synonym)|uniprotkb:Sodium channel protein cardiac muscle subunit alpha(gene name synonym)|uniprotkb:SCN5A(gene name)|psi-mi:SCN5A(display_short)|uniprotkb:hH1(gene name synonym)	psi-mi:snta1_human(display_long)|uniprotkb:59 kDa dystrophin-associated protein A1 acidic component 1(gene name synonym)|uniprotkb:Pro-TGF-alpha cytoplasmic domain-interacting protein 1(gene name synonym)|uniprotkb:Syntrophin-1(gene name synonym)|uniprotkb:SNTA1(gene name)|psi-mi:SNTA1(display_short)|uniprotkb:SNT1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Ueda et al. (2008)	pubmed:18591664|doi:10.1073/pnas.0801294105|imex:IM-9394	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15712197|imex:IM-9394-2|dip:DIP-87966E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000326.2|refseq:NP_001092874.1|refseq:NP_001092875.1|refseq:NP_001153632.1|refseq:NP_001153633.1|refseq:NP_932173.1|ensembl:ENSP00000328968|ensembl:ENST00000423572|ensembl:ENSP00000398266|ensembl:ENSG00000183873(gene)|ensembl:ENST00000333535(transcript)|go:"GO:0001518"(voltage-gated sodium channel complex)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0003161"(cardiac conduction system development)|go:"GO:0003231"(cardiac ventricle development)|go:"GO:0003360"(brainstem development)|go:"GO:0005244"(voltage-gated ion channel activity)|go:"GO:0005248"(voltage-gated sodium channel activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006814"(sodium ion transport)|go:"GO:0009986"(cell surface)|go:"GO:0010765"(positive regulation of sodium ion transport)|go:"GO:0014704"(intercalated disc)|go:"GO:0014894"(response to denervation involved in regulation of muscle adaptation)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0017134"(fibroblast growth factor binding)|go:"GO:0019228"(neuronal action potential)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0030018"(Z disc)|go:"GO:0030315"(T-tubule)|go:"GO:0030506"(ankyrin binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035725"(sodium ion transmembrane transport)|go:"GO:0042383"(sarcolemma)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045760"(positive regulation of action potential)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051899"(membrane depolarization)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060371"(regulation of atrial cardiac muscle cell membrane depolarization)|go:"GO:0060372"(regulation of atrial cardiac muscle cell membrane repolarization)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:0086002"(cardiac muscle cell action potential involved in contraction)|go:"GO:0086004"(regulation of cardiac muscle cell contraction)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0086006"(voltage-gated sodium channel activity involved in cardiac muscle cell action potential)|go:"GO:0086010"(membrane depolarization during action potential)|go:"GO:0086012"(membrane depolarization during cardiac muscle cell action potential)|go:"GO:0086014"(atrial cardiac muscle cell action potential)|go:"GO:0086015"(SA node cell action potential)|go:"GO:0086016"(AV node cell action potential)|go:"GO:0086045"(membrane depolarization during AV node cell action potential)|go:"GO:0086046"(membrane depolarization during SA node cell action potential)|go:"GO:0086047"(membrane depolarization during Purkinje myocyte cell action potential)|go:"GO:0086048"(membrane depolarization during bundle of His cell action potential)|go:"GO:0086060"(voltage-gated sodium channel activity involved in AV node cell action potential)|go:"GO:0086061"(voltage-gated sodium channel activity involved in bundle of His cell action potential)|go:"GO:0086062"(voltage-gated sodium channel activity involved in Purkinje myocyte action potential)|go:"GO:0086063"(voltage-gated sodium channel activity involved in SA node cell action potential)|go:"GO:0086067"(AV node cell to bundle of His cell communication)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098912"(membrane depolarization during atrial cardiac muscle cell action potential)|go:"GO:1902305"(regulation of sodium ion transmembrane transport)|interpro:IPR001696(Na+ channel)|interpro:IPR005821(Ion transport)|interpro:IPR008053(Na+ channel 5)|interpro:IPR010526(Sodium ion transport-associated)|interpro:IPR024583|interpro:IPR027359|interpro:IPR043203|interpro:IPR044564|rcsb pdb:2KBI|rcsb pdb:2L53|go:"GO:0086043"(bundle of His cell action potential)|rcsb pdb:4DCK|rcsb pdb:4DJC|rcsb pdb:4JQ0|rcsb pdb:4OVN|rcsb pdb:5DBR|rcsb pdb:6LQA|rcsb pdb:6MUD|rcsb pdb:7DTC|rcsb pdb:7L83|reactome:R-HSA-445095|reactome:R-HSA-5576892|dip:DIP-38416N|dip:DIP-46144N	ensembl:ENSG00000101400(gene)|ensembl:ENST00000217381(transcript)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0003117"(regulation of vasoconstriction by circulating norepinephrine)|go:"GO:0003779"(actin binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006936"(muscle contraction)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016013"(syntrophin complex)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0032991"(protein-containing complex)|refseq:NP_003089.1|ensembl:ENSP00000217381|go:"GO:0042383"(sarcolemma)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051117"(ATPase binding)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:1902083"(negative regulation of peptidyl-cysteine S-nitrosylation)|go:"GO:1902305"(regulation of sodium ion transmembrane transport)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015482(Syntrophin)|interpro:IPR028552|interpro:IPR036034|interpro:IPR041428|dip:DIP-966N	psi-mi:"MI:0465"(dip)	caution:This sequence has been withdrawn from Uniprot.	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/05	2017/08/10	rogid:WJ23sEfaxGTHEngY52K92JChA6U9606	rogid:ZeVEy6ZeNSJx2vwfHg0WaEu80OE9606	rigid:lggWFvFC0Vhoyg8iulsL4ehyKkM	false	binding-associated region:1771-2016|glutathione s tranferase tag:n-n	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q14524	uniprotkb:P29476-3	intact:EBI-726858|uniprotkb:Q59H93|uniprotkb:E9PEF3|uniprotkb:A5H1P8|uniprotkb:A6N922|uniprotkb:A6N923|uniprotkb:B2RTU0|uniprotkb:Q75RX9|uniprotkb:Q75RY0|uniprotkb:Q86UR3|uniprotkb:Q8IZC9|uniprotkb:Q96J69|uniprotkb:E9PEK2|uniprotkb:E9PFW7|uniprotkb:E7ET19|intact:EBI-28981518|ensembl:ENSP00000328968	intact:EBI-15712184	psi-mi:scn5a_human(display_long)|uniprotkb:Sodium channel protein type V subunit alpha(gene name synonym)|uniprotkb:Voltage-gated sodium channel subunit alpha Nav1.5(gene name synonym)|uniprotkb:Sodium channel protein cardiac muscle subunit alpha(gene name synonym)|uniprotkb:SCN5A(gene name)|psi-mi:SCN5A(display_short)|uniprotkb:hH1(gene name synonym)	psi-mi:p29476-3(display_long)|uniprotkb:Nos1(gene name)|psi-mi:Nos1(display_short)|uniprotkb:Bnos(gene name synonym)|uniprotkb:BNOS(gene name synonym)|uniprotkb:Constitutive NOS(gene name synonym)|uniprotkb:NC-NOS(gene name synonym)|uniprotkb:NOS type I(gene name synonym)|uniprotkb:Neuronal NOS(gene name synonym)|uniprotkb:Peptidyl-cysteine S-nitrosylase NOS1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Ueda et al. (2008)	pubmed:18591664|doi:10.1073/pnas.0801294105|imex:IM-9394	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15712197|imex:IM-9394-2|dip:DIP-87966E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000326.2|refseq:NP_001092874.1|refseq:NP_001092875.1|refseq:NP_001153632.1|refseq:NP_001153633.1|refseq:NP_932173.1|ensembl:ENSP00000328968|ensembl:ENST00000423572|ensembl:ENSP00000398266|ensembl:ENSG00000183873(gene)|ensembl:ENST00000333535(transcript)|go:"GO:0001518"(voltage-gated sodium channel complex)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0003161"(cardiac conduction system development)|go:"GO:0003231"(cardiac ventricle development)|go:"GO:0003360"(brainstem development)|go:"GO:0005244"(voltage-gated ion channel activity)|go:"GO:0005248"(voltage-gated sodium channel activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006814"(sodium ion transport)|go:"GO:0009986"(cell surface)|go:"GO:0010765"(positive regulation of sodium ion transport)|go:"GO:0014704"(intercalated disc)|go:"GO:0014894"(response to denervation involved in regulation of muscle adaptation)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0017134"(fibroblast growth factor binding)|go:"GO:0019228"(neuronal action potential)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0030018"(Z disc)|go:"GO:0030315"(T-tubule)|go:"GO:0030506"(ankyrin binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035725"(sodium ion transmembrane transport)|go:"GO:0042383"(sarcolemma)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045760"(positive regulation of action potential)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051899"(membrane depolarization)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060371"(regulation of atrial cardiac muscle cell membrane depolarization)|go:"GO:0060372"(regulation of atrial cardiac muscle cell membrane repolarization)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:0086002"(cardiac muscle cell action potential involved in contraction)|go:"GO:0086004"(regulation of cardiac muscle cell contraction)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0086006"(voltage-gated sodium channel activity involved in cardiac muscle cell action potential)|go:"GO:0086010"(membrane depolarization during action potential)|go:"GO:0086012"(membrane depolarization during cardiac muscle cell action potential)|go:"GO:0086014"(atrial cardiac muscle cell action potential)|go:"GO:0086015"(SA node cell action potential)|go:"GO:0086016"(AV node cell action potential)|go:"GO:0086045"(membrane depolarization during AV node cell action potential)|go:"GO:0086046"(membrane depolarization during SA node cell action potential)|go:"GO:0086047"(membrane depolarization during Purkinje myocyte cell action potential)|go:"GO:0086048"(membrane depolarization during bundle of His cell action potential)|go:"GO:0086060"(voltage-gated sodium channel activity involved in AV node cell action potential)|go:"GO:0086061"(voltage-gated sodium channel activity involved in bundle of His cell action potential)|go:"GO:0086062"(voltage-gated sodium channel activity involved in Purkinje myocyte action potential)|go:"GO:0086063"(voltage-gated sodium channel activity involved in SA node cell action potential)|go:"GO:0086067"(AV node cell to bundle of His cell communication)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098912"(membrane depolarization during atrial cardiac muscle cell action potential)|go:"GO:1902305"(regulation of sodium ion transmembrane transport)|interpro:IPR001696(Na+ channel)|interpro:IPR005821(Ion transport)|interpro:IPR008053(Na+ channel 5)|interpro:IPR010526(Sodium ion transport-associated)|interpro:IPR024583|interpro:IPR027359|interpro:IPR043203|interpro:IPR044564|rcsb pdb:2KBI|rcsb pdb:2L53|go:"GO:0086043"(bundle of His cell action potential)|rcsb pdb:4DCK|rcsb pdb:4DJC|rcsb pdb:4JQ0|rcsb pdb:4OVN|rcsb pdb:5DBR|rcsb pdb:6LQA|rcsb pdb:6MUD|rcsb pdb:7DTC|rcsb pdb:7L83|reactome:R-HSA-445095|reactome:R-HSA-5576892|dip:DIP-38416N|dip:DIP-46144N	intact:EBI-349460(isoform-parent)	psi-mi:"MI:0465"(dip)	caution:This sequence has been withdrawn from Uniprot.	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/05	2017/08/10	rogid:WJ23sEfaxGTHEngY52K92JChA6U9606	rogid:K160Ap9JCnixpyrZgCKXsX6czIA10116	rigid:lggWFvFC0Vhoyg8iulsL4ehyKkM	false	binding-associated region:1771-2016|glutathione s tranferase tag:n-n	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q14524	uniprotkb:Q6Q477	intact:EBI-726858|uniprotkb:Q59H93|uniprotkb:E9PEF3|uniprotkb:A5H1P8|uniprotkb:A6N922|uniprotkb:A6N923|uniprotkb:B2RTU0|uniprotkb:Q75RX9|uniprotkb:Q75RY0|uniprotkb:Q86UR3|uniprotkb:Q8IZC9|uniprotkb:Q96J69|uniprotkb:E9PEK2|uniprotkb:E9PFW7|uniprotkb:E7ET19|intact:EBI-28981518|ensembl:ENSP00000328968	intact:EBI-2308323|uniprotkb:Q32ME1|ensembl:ENSMUSP00000119242|ensembl:ENSMUSP00000133187	psi-mi:scn5a_human(display_long)|uniprotkb:Sodium channel protein type V subunit alpha(gene name synonym)|uniprotkb:Voltage-gated sodium channel subunit alpha Nav1.5(gene name synonym)|uniprotkb:Sodium channel protein cardiac muscle subunit alpha(gene name synonym)|uniprotkb:SCN5A(gene name)|psi-mi:SCN5A(display_short)|uniprotkb:hH1(gene name synonym)	psi-mi:at2b4_mouse(display_long)|uniprotkb:Atp2b4(gene name)|psi-mi:Atp2b4(display_short)	psi-mi:"MI:0096"(pull down)	Ueda et al. (2008)	pubmed:18591664|doi:10.1073/pnas.0801294105|imex:IM-9394	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15712197|imex:IM-9394-2|dip:DIP-87966E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000326.2|refseq:NP_001092874.1|refseq:NP_001092875.1|refseq:NP_001153632.1|refseq:NP_001153633.1|refseq:NP_932173.1|ensembl:ENSP00000328968|ensembl:ENST00000423572|ensembl:ENSP00000398266|ensembl:ENSG00000183873(gene)|ensembl:ENST00000333535(transcript)|go:"GO:0001518"(voltage-gated sodium channel complex)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0003161"(cardiac conduction system development)|go:"GO:0003231"(cardiac ventricle development)|go:"GO:0003360"(brainstem development)|go:"GO:0005244"(voltage-gated ion channel activity)|go:"GO:0005248"(voltage-gated sodium channel activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006814"(sodium ion transport)|go:"GO:0009986"(cell surface)|go:"GO:0010765"(positive regulation of sodium ion transport)|go:"GO:0014704"(intercalated disc)|go:"GO:0014894"(response to denervation involved in regulation of muscle adaptation)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0017134"(fibroblast growth factor binding)|go:"GO:0019228"(neuronal action potential)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0030018"(Z disc)|go:"GO:0030315"(T-tubule)|go:"GO:0030506"(ankyrin binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035725"(sodium ion transmembrane transport)|go:"GO:0042383"(sarcolemma)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045760"(positive regulation of action potential)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051899"(membrane depolarization)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060371"(regulation of atrial cardiac muscle cell membrane depolarization)|go:"GO:0060372"(regulation of atrial cardiac muscle cell membrane repolarization)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:0086002"(cardiac muscle cell action potential involved in contraction)|go:"GO:0086004"(regulation of cardiac muscle cell contraction)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0086006"(voltage-gated sodium channel activity involved in cardiac muscle cell action potential)|go:"GO:0086010"(membrane depolarization during action potential)|go:"GO:0086012"(membrane depolarization during cardiac muscle cell action potential)|go:"GO:0086014"(atrial cardiac muscle cell action potential)|go:"GO:0086015"(SA node cell action potential)|go:"GO:0086016"(AV node cell action potential)|go:"GO:0086045"(membrane depolarization during AV node cell action potential)|go:"GO:0086046"(membrane depolarization during SA node cell action potential)|go:"GO:0086047"(membrane depolarization during Purkinje myocyte cell action potential)|go:"GO:0086048"(membrane depolarization during bundle of His cell action potential)|go:"GO:0086060"(voltage-gated sodium channel activity involved in AV node cell action potential)|go:"GO:0086061"(voltage-gated sodium channel activity involved in bundle of His cell action potential)|go:"GO:0086062"(voltage-gated sodium channel activity involved in Purkinje myocyte action potential)|go:"GO:0086063"(voltage-gated sodium channel activity involved in SA node cell action potential)|go:"GO:0086067"(AV node cell to bundle of His cell communication)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098912"(membrane depolarization during atrial cardiac muscle cell action potential)|go:"GO:1902305"(regulation of sodium ion transmembrane transport)|interpro:IPR001696(Na+ channel)|interpro:IPR005821(Ion transport)|interpro:IPR008053(Na+ channel 5)|interpro:IPR010526(Sodium ion transport-associated)|interpro:IPR024583|interpro:IPR027359|interpro:IPR043203|interpro:IPR044564|rcsb pdb:2KBI|rcsb pdb:2L53|go:"GO:0086043"(bundle of His cell action potential)|rcsb pdb:4DCK|rcsb pdb:4DJC|rcsb pdb:4JQ0|rcsb pdb:4OVN|rcsb pdb:5DBR|rcsb pdb:6LQA|rcsb pdb:6MUD|rcsb pdb:7DTC|rcsb pdb:7L83|reactome:R-HSA-445095|reactome:R-HSA-5576892|dip:DIP-38416N|dip:DIP-46144N	refseq:NP_998781.1|refseq:NP_001161421.1|refseq:XP_006529786.1|refseq:XP_006529787.1|refseq:XP_006529788.1|dip:DIP-46143N|ensembl:ENSMUSG00000026463(gene)|ensembl:ENSMUST00000143567(transcript)|ensembl:ENSMUST00000165602(transcript)|go:"GO:0003407"(neural retina development)|go:"GO:0005388"(P-type calcium transporter activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0007283"(spermatogenesis)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010751"(negative regulation of nitric oxide mediated signal transduction)|go:"GO:0014832"(urinary bladder smooth muscle contraction)|go:"GO:0015085"(calcium ion transmembrane transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0019829"(ATPase-coupled cation transmembrane transporter activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0021766"(hippocampus development)|go:"GO:0030018"(Z disc)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030315"(T-tubule)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030346"(protein phosphatase 2B binding)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0036126"(sperm flagellum)|go:"GO:0036487"(nitric-oxide synthase inhibitor activity)|go:"GO:0042383"(sarcolemma)|go:"GO:0043005"(neuron projection)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043537"(negative regulation of blood vessel endothelial cell migration)|go:"GO:0045019"(negative regulation of nitric oxide biosynthetic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051599"(response to hydrostatic pressure)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0070885"(negative regulation of calcineurin-NFAT signaling cascade)|go:"GO:0071872"(cellular response to epinephrine stimulus)|go:"GO:0097228"(sperm principal piece)|go:"GO:0098736"(negative regulation of the force of heart contraction)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099059"(integral component of presynaptic active zone membrane)|go:"GO:0140199"(negative regulation of adenylate cyclase-activating adrenergic receptor signaling pathway involved in heart process)|go:"GO:1900082"(negative regulation of arginine catabolic process)|go:"GO:1901660"(calcium ion export)|go:"GO:1902548"(negative regulation of cellular response to vascular endothelial growth factor stimulus)|go:"GO:1902806"(regulation of cell cycle G1/S phase transition)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1903243"(negative regulation of cardiac muscle hypertrophy in response to stress)|go:"GO:1903249"(negative regulation of citrulline biosynthetic process)|go:"GO:1905145"(cellular response to acetylcholine)|go:"GO:2000481"(positive regulation of cAMP-dependent protein kinase activity)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|interpro:IPR004014(ATPase, P-type cation-transporter, N-terminal)|interpro:IPR006068(ATPase, P-type cation-transporter, C-terminal)|interpro:IPR006408(Calcium-translocating P-type ATPase, PMCA-type)|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR018303|interpro:IPR022141|interpro:IPR023214|interpro:IPR023298|interpro:IPR023299|interpro:IPR036412|interpro:IPR044492|reactome:R-MMU-418359|reactome:R-MMU-5578775|reactome:R-MMU-936837	psi-mi:"MI:0465"(dip)	caution:This sequence has been withdrawn from Uniprot.	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/05	2017/08/10	rogid:WJ23sEfaxGTHEngY52K92JChA6U9606	rogid:IV80bQo2/6AW0+lxIhWZcRIFXBE10090	rigid:lggWFvFC0Vhoyg8iulsL4ehyKkM	false	binding-associated region:1771-2016|glutathione s tranferase tag:n-n	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q14524	uniprotkb:Q13424	intact:EBI-726858|uniprotkb:Q59H93|uniprotkb:E9PEF3|uniprotkb:A5H1P8|uniprotkb:A6N922|uniprotkb:A6N923|uniprotkb:B2RTU0|uniprotkb:Q75RX9|uniprotkb:Q75RY0|uniprotkb:Q86UR3|uniprotkb:Q8IZC9|uniprotkb:Q96J69|uniprotkb:E9PEK2|uniprotkb:E9PFW7|uniprotkb:E7ET19|intact:EBI-28981518|ensembl:ENSP00000328968	intact:EBI-717191|intact:EBI-28985258|ensembl:ENSP00000217381|uniprotkb:Q16438|uniprotkb:A8K7H9|uniprotkb:E1P5N1|uniprotkb:B4DX40	psi-mi:scn5a_human(display_long)|uniprotkb:Sodium channel protein type V subunit alpha(gene name synonym)|uniprotkb:Voltage-gated sodium channel subunit alpha Nav1.5(gene name synonym)|uniprotkb:Sodium channel protein cardiac muscle subunit alpha(gene name synonym)|uniprotkb:SCN5A(gene name)|psi-mi:SCN5A(display_short)|uniprotkb:hH1(gene name synonym)	psi-mi:snta1_human(display_long)|uniprotkb:59 kDa dystrophin-associated protein A1 acidic component 1(gene name synonym)|uniprotkb:Pro-TGF-alpha cytoplasmic domain-interacting protein 1(gene name synonym)|uniprotkb:Syntrophin-1(gene name synonym)|uniprotkb:SNTA1(gene name)|psi-mi:SNTA1(display_short)|uniprotkb:SNT1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Ueda et al. (2008)	pubmed:18591664|doi:10.1073/pnas.0801294105|imex:IM-9394	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15712238|imex:IM-9394-4|dip:DIP-87967E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000326.2|refseq:NP_001092874.1|refseq:NP_001092875.1|refseq:NP_001153632.1|refseq:NP_001153633.1|refseq:NP_932173.1|ensembl:ENSP00000328968|ensembl:ENST00000423572|ensembl:ENSP00000398266|ensembl:ENSG00000183873(gene)|ensembl:ENST00000333535(transcript)|go:"GO:0001518"(voltage-gated sodium channel complex)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0003161"(cardiac conduction system development)|go:"GO:0003231"(cardiac ventricle development)|go:"GO:0003360"(brainstem development)|go:"GO:0005244"(voltage-gated ion channel activity)|go:"GO:0005248"(voltage-gated sodium channel activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006814"(sodium ion transport)|go:"GO:0009986"(cell surface)|go:"GO:0010765"(positive regulation of sodium ion transport)|go:"GO:0014704"(intercalated disc)|go:"GO:0014894"(response to denervation involved in regulation of muscle adaptation)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0017134"(fibroblast growth factor binding)|go:"GO:0019228"(neuronal action potential)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0030018"(Z disc)|go:"GO:0030315"(T-tubule)|go:"GO:0030506"(ankyrin binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035725"(sodium ion transmembrane transport)|go:"GO:0042383"(sarcolemma)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045760"(positive regulation of action potential)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051899"(membrane depolarization)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060371"(regulation of atrial cardiac muscle cell membrane depolarization)|go:"GO:0060372"(regulation of atrial cardiac muscle cell membrane repolarization)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:0086002"(cardiac muscle cell action potential involved in contraction)|go:"GO:0086004"(regulation of cardiac muscle cell contraction)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0086006"(voltage-gated sodium channel activity involved in cardiac muscle cell action potential)|go:"GO:0086010"(membrane depolarization during action potential)|go:"GO:0086012"(membrane depolarization during cardiac muscle cell action potential)|go:"GO:0086014"(atrial cardiac muscle cell action potential)|go:"GO:0086015"(SA node cell action potential)|go:"GO:0086016"(AV node cell action potential)|go:"GO:0086045"(membrane depolarization during AV node cell action potential)|go:"GO:0086046"(membrane depolarization during SA node cell action potential)|go:"GO:0086047"(membrane depolarization during Purkinje myocyte cell action potential)|go:"GO:0086048"(membrane depolarization during bundle of His cell action potential)|go:"GO:0086060"(voltage-gated sodium channel activity involved in AV node cell action potential)|go:"GO:0086061"(voltage-gated sodium channel activity involved in bundle of His cell action potential)|go:"GO:0086062"(voltage-gated sodium channel activity involved in Purkinje myocyte action potential)|go:"GO:0086063"(voltage-gated sodium channel activity involved in SA node cell action potential)|go:"GO:0086067"(AV node cell to bundle of His cell communication)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098912"(membrane depolarization during atrial cardiac muscle cell action potential)|go:"GO:1902305"(regulation of sodium ion transmembrane transport)|interpro:IPR001696(Na+ channel)|interpro:IPR005821(Ion transport)|interpro:IPR008053(Na+ channel 5)|interpro:IPR010526(Sodium ion transport-associated)|interpro:IPR024583|interpro:IPR027359|interpro:IPR043203|interpro:IPR044564|rcsb pdb:2KBI|rcsb pdb:2L53|go:"GO:0086043"(bundle of His cell action potential)|rcsb pdb:4DCK|rcsb pdb:4DJC|rcsb pdb:4JQ0|rcsb pdb:4OVN|rcsb pdb:5DBR|rcsb pdb:6LQA|rcsb pdb:6MUD|rcsb pdb:7DTC|rcsb pdb:7L83|reactome:R-HSA-445095|reactome:R-HSA-5576892|dip:DIP-38416N|dip:DIP-46144N	ensembl:ENSG00000101400(gene)|ensembl:ENST00000217381(transcript)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0003117"(regulation of vasoconstriction by circulating norepinephrine)|go:"GO:0003779"(actin binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006936"(muscle contraction)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016013"(syntrophin complex)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0032991"(protein-containing complex)|refseq:NP_003089.1|ensembl:ENSP00000217381|go:"GO:0042383"(sarcolemma)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051117"(ATPase binding)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:1902083"(negative regulation of peptidyl-cysteine S-nitrosylation)|go:"GO:1902305"(regulation of sodium ion transmembrane transport)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015482(Syntrophin)|interpro:IPR028552|interpro:IPR036034|interpro:IPR041428|dip:DIP-966N	psi-mi:"MI:0465"(dip)	caution:This sequence has been withdrawn from Uniprot.	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/05	2017/08/10	rogid:WJ23sEfaxGTHEngY52K92JChA6U9606	rogid:ZeVEy6ZeNSJx2vwfHg0WaEu80OE9606	rigid:DDaxM1rF0nuVYtBK6ChMaJ1igRA	false	binding-associated region:1771-2016|glutathione s tranferase tag:n-n	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q14524	uniprotkb:P29476-3	intact:EBI-726858|uniprotkb:Q59H93|uniprotkb:E9PEF3|uniprotkb:A5H1P8|uniprotkb:A6N922|uniprotkb:A6N923|uniprotkb:B2RTU0|uniprotkb:Q75RX9|uniprotkb:Q75RY0|uniprotkb:Q86UR3|uniprotkb:Q8IZC9|uniprotkb:Q96J69|uniprotkb:E9PEK2|uniprotkb:E9PFW7|uniprotkb:E7ET19|intact:EBI-28981518|ensembl:ENSP00000328968	intact:EBI-15712184	psi-mi:scn5a_human(display_long)|uniprotkb:Sodium channel protein type V subunit alpha(gene name synonym)|uniprotkb:Voltage-gated sodium channel subunit alpha Nav1.5(gene name synonym)|uniprotkb:Sodium channel protein cardiac muscle subunit alpha(gene name synonym)|uniprotkb:SCN5A(gene name)|psi-mi:SCN5A(display_short)|uniprotkb:hH1(gene name synonym)	psi-mi:p29476-3(display_long)|uniprotkb:Nos1(gene name)|psi-mi:Nos1(display_short)|uniprotkb:Bnos(gene name synonym)|uniprotkb:BNOS(gene name synonym)|uniprotkb:Constitutive NOS(gene name synonym)|uniprotkb:NC-NOS(gene name synonym)|uniprotkb:NOS type I(gene name synonym)|uniprotkb:Neuronal NOS(gene name synonym)|uniprotkb:Peptidyl-cysteine S-nitrosylase NOS1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Ueda et al. (2008)	pubmed:18591664|doi:10.1073/pnas.0801294105|imex:IM-9394	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15712238|imex:IM-9394-4|dip:DIP-87967E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000326.2|refseq:NP_001092874.1|refseq:NP_001092875.1|refseq:NP_001153632.1|refseq:NP_001153633.1|refseq:NP_932173.1|ensembl:ENSP00000328968|ensembl:ENST00000423572|ensembl:ENSP00000398266|ensembl:ENSG00000183873(gene)|ensembl:ENST00000333535(transcript)|go:"GO:0001518"(voltage-gated sodium channel complex)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0003161"(cardiac conduction system development)|go:"GO:0003231"(cardiac ventricle development)|go:"GO:0003360"(brainstem development)|go:"GO:0005244"(voltage-gated ion channel activity)|go:"GO:0005248"(voltage-gated sodium channel activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006814"(sodium ion transport)|go:"GO:0009986"(cell surface)|go:"GO:0010765"(positive regulation of sodium ion transport)|go:"GO:0014704"(intercalated disc)|go:"GO:0014894"(response to denervation involved in regulation of muscle adaptation)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0017134"(fibroblast growth factor binding)|go:"GO:0019228"(neuronal action potential)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0030018"(Z disc)|go:"GO:0030315"(T-tubule)|go:"GO:0030506"(ankyrin binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035725"(sodium ion transmembrane transport)|go:"GO:0042383"(sarcolemma)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045760"(positive regulation of action potential)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051899"(membrane depolarization)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060371"(regulation of atrial cardiac muscle cell membrane depolarization)|go:"GO:0060372"(regulation of atrial cardiac muscle cell membrane repolarization)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:0086002"(cardiac muscle cell action potential involved in contraction)|go:"GO:0086004"(regulation of cardiac muscle cell contraction)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0086006"(voltage-gated sodium channel activity involved in cardiac muscle cell action potential)|go:"GO:0086010"(membrane depolarization during action potential)|go:"GO:0086012"(membrane depolarization during cardiac muscle cell action potential)|go:"GO:0086014"(atrial cardiac muscle cell action potential)|go:"GO:0086015"(SA node cell action potential)|go:"GO:0086016"(AV node cell action potential)|go:"GO:0086045"(membrane depolarization during AV node cell action potential)|go:"GO:0086046"(membrane depolarization during SA node cell action potential)|go:"GO:0086047"(membrane depolarization during Purkinje myocyte cell action potential)|go:"GO:0086048"(membrane depolarization during bundle of His cell action potential)|go:"GO:0086060"(voltage-gated sodium channel activity involved in AV node cell action potential)|go:"GO:0086061"(voltage-gated sodium channel activity involved in bundle of His cell action potential)|go:"GO:0086062"(voltage-gated sodium channel activity involved in Purkinje myocyte action potential)|go:"GO:0086063"(voltage-gated sodium channel activity involved in SA node cell action potential)|go:"GO:0086067"(AV node cell to bundle of His cell communication)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098912"(membrane depolarization during atrial cardiac muscle cell action potential)|go:"GO:1902305"(regulation of sodium ion transmembrane transport)|interpro:IPR001696(Na+ channel)|interpro:IPR005821(Ion transport)|interpro:IPR008053(Na+ channel 5)|interpro:IPR010526(Sodium ion transport-associated)|interpro:IPR024583|interpro:IPR027359|interpro:IPR043203|interpro:IPR044564|rcsb pdb:2KBI|rcsb pdb:2L53|go:"GO:0086043"(bundle of His cell action potential)|rcsb pdb:4DCK|rcsb pdb:4DJC|rcsb pdb:4JQ0|rcsb pdb:4OVN|rcsb pdb:5DBR|rcsb pdb:6LQA|rcsb pdb:6MUD|rcsb pdb:7DTC|rcsb pdb:7L83|reactome:R-HSA-445095|reactome:R-HSA-5576892|dip:DIP-38416N|dip:DIP-46144N	intact:EBI-349460(isoform-parent)	psi-mi:"MI:0465"(dip)	caution:This sequence has been withdrawn from Uniprot.	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/05	2017/08/10	rogid:WJ23sEfaxGTHEngY52K92JChA6U9606	rogid:K160Ap9JCnixpyrZgCKXsX6czIA10116	rigid:DDaxM1rF0nuVYtBK6ChMaJ1igRA	false	binding-associated region:1771-2016|glutathione s tranferase tag:n-n	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)