#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q3U2S8	uniprotkb:Q3U2S8	intact:EBI-8401579|uniprotkb:Q9DCE4|intact:MINT-4128643|ensembl:ENSMUSP00000072401|ensembl:ENSMUSP00000098312	intact:EBI-8401579|uniprotkb:Q9DCE4|intact:MINT-4128643|ensembl:ENSMUSP00000072401|ensembl:ENSMUSP00000098312	psi-mi:hvcn1_mouse(display_long)|uniprotkb:Hvcn1(gene name)|psi-mi:Hvcn1(display_short)|uniprotkb:Bts(gene name synonym)|uniprotkb:Vsop(gene name synonym)|uniprotkb:Hydrogen voltage-gated channel 1(gene name synonym)|uniprotkb:Voltage sensor domain-only protein(gene name synonym)	psi-mi:hvcn1_mouse(display_long)|uniprotkb:Hvcn1(gene name)|psi-mi:Hvcn1(display_short)|uniprotkb:Bts(gene name synonym)|uniprotkb:Vsop(gene name synonym)|uniprotkb:Hydrogen voltage-gated channel 1(gene name synonym)|uniprotkb:Voltage sensor domain-only protein(gene name synonym)	psi-mi:"MI:0404"(comigration in non denaturing gel electrophoresis)	Koch et al. (2008)	pubmed:18583477|doi:10.1073/pnas.0801553105|imex:IM-9387	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15711542|imex:IM-9387-1|dip:DIP-87953E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_083028.1|refseq:NP_001035954.1|refseq:XP_006530535.1|refseq:XP_006530536.1|dip:DIP-46134N|ensembl:ENSMUSG00000064267(gene)|ensembl:ENSMUST00000072602(transcript)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0009268"(response to pH)|go:"GO:0010043"(response to zinc ion)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0022843"(voltage-gated cation channel activity)|go:"GO:0030171"(voltage-gated proton channel activity)|go:"GO:0032930"(positive regulation of superoxide anion generation)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0042802"(identical protein binding)|go:"GO:0051453"(regulation of intracellular pH)|go:"GO:0071294"(cellular response to zinc ion)|go:"GO:0071467"(cellular response to pH)|go:"GO:1902600"(proton transmembrane transport)|interpro:IPR005821(Ion transport)|interpro:IPR027359|interpro:IPR031844|interpro:IPR031846|mint:Q3U2S8|rcsb pdb:3VMX|rcsb pdb:3VMY|rcsb pdb:3VMZ|rcsb pdb:3VN0|rcsb pdb:3VYI|rcsb pdb:3WKV|reactome:R-MMU-1222556|reactome:R-MMU-1300642|reactome:R-MMU-6798695|ensembl:ENSMUST00000100747(transcript)	refseq:NP_083028.1|refseq:NP_001035954.1|refseq:XP_006530535.1|refseq:XP_006530536.1|dip:DIP-46134N|ensembl:ENSMUSG00000064267(gene)|ensembl:ENSMUST00000072602(transcript)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0009268"(response to pH)|go:"GO:0010043"(response to zinc ion)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0022843"(voltage-gated cation channel activity)|go:"GO:0030171"(voltage-gated proton channel activity)|go:"GO:0032930"(positive regulation of superoxide anion generation)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0042802"(identical protein binding)|go:"GO:0051453"(regulation of intracellular pH)|go:"GO:0071294"(cellular response to zinc ion)|go:"GO:0071467"(cellular response to pH)|go:"GO:1902600"(proton transmembrane transport)|interpro:IPR005821(Ion transport)|interpro:IPR027359|interpro:IPR031844|interpro:IPR031846|mint:Q3U2S8|rcsb pdb:3VMX|rcsb pdb:3VMY|rcsb pdb:3VMZ|rcsb pdb:3VN0|rcsb pdb:3VYI|rcsb pdb:3WKV|reactome:R-MMU-1222556|reactome:R-MMU-1300642|reactome:R-MMU-6798695|ensembl:ENSMUST00000100747(transcript)	psi-mi:"MI:0465"(dip)	comment:mint	comment:mint	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2017/08/05	2017/08/10	rogid:0YweJrbX8XX0Ni/bAEZcBBqzLg410090	rogid:0YweJrbX8XX0Ni/bAEZcBBqzLg410090	rigid:WRaT6raBr7ehtR0r59w24xCkE8I	false	-	-	-	0	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q1JV40	uniprotkb:Q1JV40	intact:EBI-15711579|ensembl:ENSCINP00000026518	intact:EBI-15711579|ensembl:ENSCINP00000026518	psi-mi:hvcn1_cioin(display_long)|uniprotkb:HVCN1(gene name)|psi-mi:HVCN1(display_short)|uniprotkb:VSOP(gene name synonym)|uniprotkb:VSX1(gene name synonym)|uniprotkb:Hydrogen voltage-gated channel 1(gene name synonym)|uniprotkb:Voltage sensor domain-only protein(gene name synonym)	psi-mi:hvcn1_cioin(display_long)|uniprotkb:HVCN1(gene name)|psi-mi:HVCN1(display_short)|uniprotkb:VSOP(gene name synonym)|uniprotkb:VSX1(gene name synonym)|uniprotkb:Hydrogen voltage-gated channel 1(gene name synonym)|uniprotkb:Voltage sensor domain-only protein(gene name synonym)	psi-mi:"MI:0055"(fluorescent resonance energy transfer)	Koch et al. (2008)	pubmed:18583477|doi:10.1073/pnas.0801553105|imex:IM-9387	taxid:7719(cioin)|taxid:7719(cioin)	taxid:7719(cioin)|taxid:7719(cioin)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15711599|imex:IM-9387-3|dip:DIP-87954E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSCING00000014744(gene)|ensembl:ENSCINT00000026764(transcript)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0030171"(voltage-gated proton channel activity)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0071294"(cellular response to zinc ion)|go:"GO:0071467"(cellular response to pH)|go:"GO:1902600"(proton transmembrane transport)|interpro:IPR005821(Ion transport)|interpro:IPR027359|interpro:IPR031846|refseq:NP_001071937.1|dip:DIP-46135N	ensembl:ENSCING00000014744(gene)|ensembl:ENSCINT00000026764(transcript)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0030171"(voltage-gated proton channel activity)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0071294"(cellular response to zinc ion)|go:"GO:0071467"(cellular response to pH)|go:"GO:1902600"(proton transmembrane transport)|interpro:IPR005821(Ion transport)|interpro:IPR027359|interpro:IPR031846|refseq:NP_001071937.1|dip:DIP-46135N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:8355(xenla)|taxid:8355("Xenopus laevis (African clawed frog)")	-	2017/08/05	2017/08/10	rogid:AbxIQavn6e5fuMN/LqNxHTCi0mw7719	rogid:AbxIQavn6e5fuMN/LqNxHTCi0mw7719	rigid:F31ichHdbJqqng4QhiiMGaFYtBs	false	mutation increasing interaction:242-242	mutation increasing interaction:242-242	-	0	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q3U2S8	uniprotkb:Q3U2S8	intact:EBI-8401579|uniprotkb:Q9DCE4|intact:MINT-4128643|ensembl:ENSMUSP00000072401|ensembl:ENSMUSP00000098312	intact:EBI-8401579|uniprotkb:Q9DCE4|intact:MINT-4128643|ensembl:ENSMUSP00000072401|ensembl:ENSMUSP00000098312	psi-mi:hvcn1_mouse(display_long)|uniprotkb:Hvcn1(gene name)|psi-mi:Hvcn1(display_short)|uniprotkb:Bts(gene name synonym)|uniprotkb:Vsop(gene name synonym)|uniprotkb:Hydrogen voltage-gated channel 1(gene name synonym)|uniprotkb:Voltage sensor domain-only protein(gene name synonym)	psi-mi:hvcn1_mouse(display_long)|uniprotkb:Hvcn1(gene name)|psi-mi:Hvcn1(display_short)|uniprotkb:Bts(gene name synonym)|uniprotkb:Vsop(gene name synonym)|uniprotkb:Hydrogen voltage-gated channel 1(gene name synonym)|uniprotkb:Voltage sensor domain-only protein(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Koch et al. (2008)	pubmed:18583477|doi:10.1073/pnas.0801553105|imex:IM-9387	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15711558|imex:IM-9387-2|dip:DIP-87953E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_083028.1|refseq:NP_001035954.1|refseq:XP_006530535.1|refseq:XP_006530536.1|dip:DIP-46134N|ensembl:ENSMUSG00000064267(gene)|ensembl:ENSMUST00000072602(transcript)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0009268"(response to pH)|go:"GO:0010043"(response to zinc ion)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0022843"(voltage-gated cation channel activity)|go:"GO:0030171"(voltage-gated proton channel activity)|go:"GO:0032930"(positive regulation of superoxide anion generation)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0042802"(identical protein binding)|go:"GO:0051453"(regulation of intracellular pH)|go:"GO:0071294"(cellular response to zinc ion)|go:"GO:0071467"(cellular response to pH)|go:"GO:1902600"(proton transmembrane transport)|interpro:IPR005821(Ion transport)|interpro:IPR027359|interpro:IPR031844|interpro:IPR031846|mint:Q3U2S8|rcsb pdb:3VMX|rcsb pdb:3VMY|rcsb pdb:3VMZ|rcsb pdb:3VN0|rcsb pdb:3VYI|rcsb pdb:3WKV|reactome:R-MMU-1222556|reactome:R-MMU-1300642|reactome:R-MMU-6798695|ensembl:ENSMUST00000100747(transcript)	refseq:NP_083028.1|refseq:NP_001035954.1|refseq:XP_006530535.1|refseq:XP_006530536.1|dip:DIP-46134N|ensembl:ENSMUSG00000064267(gene)|ensembl:ENSMUST00000072602(transcript)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0009268"(response to pH)|go:"GO:0010043"(response to zinc ion)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0022843"(voltage-gated cation channel activity)|go:"GO:0030171"(voltage-gated proton channel activity)|go:"GO:0032930"(positive regulation of superoxide anion generation)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0042802"(identical protein binding)|go:"GO:0051453"(regulation of intracellular pH)|go:"GO:0071294"(cellular response to zinc ion)|go:"GO:0071467"(cellular response to pH)|go:"GO:1902600"(proton transmembrane transport)|interpro:IPR005821(Ion transport)|interpro:IPR027359|interpro:IPR031844|interpro:IPR031846|mint:Q3U2S8|rcsb pdb:3VMX|rcsb pdb:3VMY|rcsb pdb:3VMZ|rcsb pdb:3VN0|rcsb pdb:3VYI|rcsb pdb:3WKV|reactome:R-MMU-1222556|reactome:R-MMU-1300642|reactome:R-MMU-6798695|ensembl:ENSMUST00000100747(transcript)	psi-mi:"MI:0465"(dip)	comment:mint	comment:mint	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2017/08/05	2017/08/10	rogid:0YweJrbX8XX0Ni/bAEZcBBqzLg410090	rogid:0YweJrbX8XX0Ni/bAEZcBBqzLg410090	rigid:oNcLMkl57AO47jAjTcyNIl+BS9M	false	ha tag:c-c	myc tag:c-c	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q3U2S8	uniprotkb:Q3U2S8	intact:EBI-8401579|uniprotkb:Q9DCE4|intact:MINT-4128643|ensembl:ENSMUSP00000072401|ensembl:ENSMUSP00000098312	intact:EBI-8401579|uniprotkb:Q9DCE4|intact:MINT-4128643|ensembl:ENSMUSP00000072401|ensembl:ENSMUSP00000098312	psi-mi:hvcn1_mouse(display_long)|uniprotkb:Hvcn1(gene name)|psi-mi:Hvcn1(display_short)|uniprotkb:Bts(gene name synonym)|uniprotkb:Vsop(gene name synonym)|uniprotkb:Hydrogen voltage-gated channel 1(gene name synonym)|uniprotkb:Voltage sensor domain-only protein(gene name synonym)	psi-mi:hvcn1_mouse(display_long)|uniprotkb:Hvcn1(gene name)|psi-mi:Hvcn1(display_short)|uniprotkb:Bts(gene name synonym)|uniprotkb:Vsop(gene name synonym)|uniprotkb:Hydrogen voltage-gated channel 1(gene name synonym)|uniprotkb:Voltage sensor domain-only protein(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Koch et al. (2008)	pubmed:18583477|doi:10.1073/pnas.0801553105|imex:IM-9387	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15711618|imex:IM-9387-4|dip:DIP-87953E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_083028.1|refseq:NP_001035954.1|refseq:XP_006530535.1|refseq:XP_006530536.1|dip:DIP-46134N|ensembl:ENSMUSG00000064267(gene)|ensembl:ENSMUST00000072602(transcript)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0009268"(response to pH)|go:"GO:0010043"(response to zinc ion)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0022843"(voltage-gated cation channel activity)|go:"GO:0030171"(voltage-gated proton channel activity)|go:"GO:0032930"(positive regulation of superoxide anion generation)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0042802"(identical protein binding)|go:"GO:0051453"(regulation of intracellular pH)|go:"GO:0071294"(cellular response to zinc ion)|go:"GO:0071467"(cellular response to pH)|go:"GO:1902600"(proton transmembrane transport)|interpro:IPR005821(Ion transport)|interpro:IPR027359|interpro:IPR031844|interpro:IPR031846|mint:Q3U2S8|rcsb pdb:3VMX|rcsb pdb:3VMY|rcsb pdb:3VMZ|rcsb pdb:3VN0|rcsb pdb:3VYI|rcsb pdb:3WKV|reactome:R-MMU-1222556|reactome:R-MMU-1300642|reactome:R-MMU-6798695|ensembl:ENSMUST00000100747(transcript)	refseq:NP_083028.1|refseq:NP_001035954.1|refseq:XP_006530535.1|refseq:XP_006530536.1|dip:DIP-46134N|ensembl:ENSMUSG00000064267(gene)|ensembl:ENSMUST00000072602(transcript)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0009268"(response to pH)|go:"GO:0010043"(response to zinc ion)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0022843"(voltage-gated cation channel activity)|go:"GO:0030171"(voltage-gated proton channel activity)|go:"GO:0032930"(positive regulation of superoxide anion generation)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0042802"(identical protein binding)|go:"GO:0051453"(regulation of intracellular pH)|go:"GO:0071294"(cellular response to zinc ion)|go:"GO:0071467"(cellular response to pH)|go:"GO:1902600"(proton transmembrane transport)|interpro:IPR005821(Ion transport)|interpro:IPR027359|interpro:IPR031844|interpro:IPR031846|mint:Q3U2S8|rcsb pdb:3VMX|rcsb pdb:3VMY|rcsb pdb:3VMZ|rcsb pdb:3VN0|rcsb pdb:3VYI|rcsb pdb:3WKV|reactome:R-MMU-1222556|reactome:R-MMU-1300642|reactome:R-MMU-6798695|ensembl:ENSMUST00000100747(transcript)	psi-mi:"MI:0465"(dip)	comment:mint	comment:mint	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2017/08/05	2017/08/10	rogid:0YweJrbX8XX0Ni/bAEZcBBqzLg410090	rogid:0YweJrbX8XX0Ni/bAEZcBBqzLg410090	rigid:oNcLMkl57AO47jAjTcyNIl+BS9M	false	ha tag:c-c	myc tag:c-c	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)