#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q13936 uniprotkb:Q08289-1 intact:EBI-1038838|uniprotkb:Q13917|uniprotkb:Q13918|uniprotkb:Q13919|uniprotkb:Q13920|uniprotkb:Q13921|uniprotkb:Q13922|uniprotkb:Q13923|uniprotkb:Q13924|uniprotkb:Q13925|uniprotkb:Q13926|uniprotkb:Q13927|uniprotkb:Q13928|uniprotkb:Q13929|uniprotkb:Q13930|uniprotkb:Q13932|uniprotkb:Q13933|uniprotkb:Q14743|uniprotkb:Q14744|uniprotkb:Q15877|uniprotkb:Q4VMI7|uniprotkb:Q4VMI8|uniprotkb:Q4VMI9|uniprotkb:Q6PKM7|uniprotkb:Q8N6C0|uniprotkb:Q99025|uniprotkb:Q99241|uniprotkb:Q99875|uniprotkb:B2RUT3|uniprotkb:E9PDJ0 intact:EBI-15707999|ensembl:ENSP00000320025 psi-mi:cac1c_human(display_long)|uniprotkb:CACNA1C(gene name)|psi-mi:CACNA1C(display_short)|uniprotkb:CACH2(gene name synonym)|uniprotkb:CACN2(gene name synonym)|uniprotkb:CACNL1A1(gene name synonym)|uniprotkb:CCHL1A1(gene name synonym)|uniprotkb:Voltage-gated calcium channel subunit alpha Cav1.2(gene name synonym)|uniprotkb:Calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle(gene name synonym) psi-mi:q08289-1(display_long)|uniprotkb:CACNB2(gene name)|psi-mi:CACNB2(display_short)|uniprotkb:CACNLB2(gene name synonym)|uniprotkb:MYSB(gene name synonym)|uniprotkb:CACNB2d(isoform synonym)|uniprotkb:Calcium channel voltage-dependent subunit beta 2(gene name synonym)|uniprotkb:Lambert-Eaton myasthenic syndrome antigen B(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ravindran et al. (2008) pubmed:18535142|doi:10.1073/pnas.0711624105|imex:IM-9366 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15708009|imex:IM-9366-3|dip:DIP-87913E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000710.5|refseq:NP_001123299.1|refseq:NP_001123301.1|refseq:NP_001123303.1|refseq:NP_001123304.1|refseq:NP_001123305.1|refseq:NP_001123306.1|refseq:NP_001123307.1|refseq:NP_001123314.1|refseq:NP_001123315.1|refseq:NP_001123308.1|refseq:NP_001123309.1|refseq:NP_001123310.1|refseq:NP_001123311.1|refseq:NP_001123312.1|refseq:NP_001123313.1|refseq:NP_001123316.1|refseq:NP_001123318.1|refseq:NP_001161095.1|refseq:NP_001161097.1|refseq:NP_001123302.2|refseq:NP_001161096.2|refseq:NP_955630.3|reactome:R-HSA-5576893|reactome:R-HSA-400042|reactome:R-HSA-419037|reactome:R-HSA-422356|go:"GO:0002520"(immune system development)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007507"(heart development)|go:"GO:0008331"(high voltage-gated calcium channel activity)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030018"(Z disc)|go:"GO:0030425"(dendrite)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035585"(calcium-mediated signaling using extracellular calcium source)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043204"(perikaryon)|go:"GO:0045762"(positive regulation of adenylate cyclase activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0051393"(alpha-actinin binding)|go:"GO:0060402"(calcium ion transport into cytosol)|go:"GO:0061337"(cardiac conduction)|go:"GO:0061577"(calcium ion transmembrane transport via high voltage-gated calcium channel)|go:"GO:0070509"(calcium ion import)|go:"GO:0086002"(cardiac muscle cell action potential involved in contraction)|go:"GO:0086007"(voltage-gated calcium channel activity involved in cardiac muscle cell action potential)|go:"GO:0086012"(membrane depolarization during cardiac muscle cell action potential)|go:"GO:0086045"(membrane depolarization during AV node cell action potential)|go:"GO:0086056"(voltage-gated calcium channel activity involved in AV node cell action potential)|go:"GO:0086064"(cell communication by electrical coupling involved in cardiac conduction)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|go:"GO:0098912"(membrane depolarization during atrial cardiac muscle cell action potential)|go:"GO:1990454"(L-type voltage-gated calcium channel complex)|interpro:IPR002077(Voltage-dependent calcium channel, alpha-1 subunit)|interpro:IPR005446(Voltage-dependent calcium channel, L-type, alpha-1 subunit)|interpro:IPR005451(Voltage-dependent calcium channel, L-type, alpha-1C subunit)|interpro:IPR005821(Ion transport)|interpro:IPR014873(Voltage-dependent calcium channel, alpha-1 subunit, IQ domain)|interpro:IPR027359|interpro:IPR031649|interpro:IPR031688|rcsb pdb:1T0J|rcsb pdb:2BE6|rcsb pdb:2F3Y|rcsb pdb:2F3Z|rcsb pdb:2LQC|rcsb pdb:3G43|rcsb pdb:3OXQ|rcsb pdb:5V2P|rcsb pdb:5V2Q|rcsb pdb:6C0A|rcsb pdb:6DAD|rcsb pdb:6DAE|rcsb pdb:6DAF|rcsb pdb:6U39|rcsb pdb:6U3A|rcsb pdb:6U3B|rcsb pdb:6U3D|go:"GO:0070588"(calcium ion transmembrane transport)|reactome:R-HSA-5576892|dip:DIP-29589N ensembl:ENSG00000165995(gene)|ensembl:ENST00000324631(transcript)|intact:EBI-2874501(isoform-parent) psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9534(chlae)|taxid:9534(Chlorocebus aethiops) - 2017/08/05 2019/04/16 rogid:dhWcWUTulWYd/nQtGorjr481/XA9606 rogid:62aD9Wbg0RTCIwNCGexJvVgKkGE9606 rigid:r6cIsUDzOA8pL9P1O1RVo3ATZzM false flag tag:n-n fluorescent protein tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P54284 uniprotkb:Q13936 intact:EBI-1184651|uniprotkb:Q13913|uniprotkb:A8K0Z4|ensembl:ENSP00000301050|uniprotkb:B7Z4Q1|uniprotkb:B7Z973|uniprotkb:B7ZAK8|uniprotkb:F5GZW7|uniprotkb:F5H2P6|uniprotkb:F8VSG3 intact:EBI-1038838|uniprotkb:Q13917|uniprotkb:Q13918|uniprotkb:Q13919|uniprotkb:Q13920|uniprotkb:Q13921|uniprotkb:Q13922|uniprotkb:Q13923|uniprotkb:Q13924|uniprotkb:Q13925|uniprotkb:Q13926|uniprotkb:Q13927|uniprotkb:Q13928|uniprotkb:Q13929|uniprotkb:Q13930|uniprotkb:Q13932|uniprotkb:Q13933|uniprotkb:Q14743|uniprotkb:Q14744|uniprotkb:Q15877|uniprotkb:Q4VMI7|uniprotkb:Q4VMI8|uniprotkb:Q4VMI9|uniprotkb:Q6PKM7|uniprotkb:Q8N6C0|uniprotkb:Q99025|uniprotkb:Q99241|uniprotkb:Q99875|uniprotkb:B2RUT3|uniprotkb:E9PDJ0 psi-mi:cacb3_human(display_long)|uniprotkb:CACNB3(gene name)|psi-mi:CACNB3(display_short)|uniprotkb:CACNLB3(gene name synonym)|uniprotkb:Calcium channel voltage-dependent subunit beta 3(gene name synonym) psi-mi:cac1c_human(display_long)|uniprotkb:CACNA1C(gene name)|psi-mi:CACNA1C(display_short)|uniprotkb:CACH2(gene name synonym)|uniprotkb:CACN2(gene name synonym)|uniprotkb:CACNL1A1(gene name synonym)|uniprotkb:CCHL1A1(gene name synonym)|uniprotkb:Voltage-gated calcium channel subunit alpha Cav1.2(gene name synonym)|uniprotkb:Calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ravindran et al. (2008) pubmed:18535142|doi:10.1073/pnas.0711624105|imex:IM-9366 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15707980|imex:IM-9366-2|dip:DIP-87916E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000716.2|ensembl:ENSG00000167535(gene)|ensembl:ENST00000301050(transcript)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005829"(cytosol)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0008331"(high voltage-gated calcium channel activity)|go:"GO:0016020"(membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0045202"(synapse)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050966"(detection of mechanical stimulus involved in sensory perception of pain)|go:"GO:0060402"(calcium ion transport into cytosol)|go:"GO:0061577"(calcium ion transmembrane transport via high voltage-gated calcium channel)|go:"GO:0072659"(protein localization to plasma membrane)|interpro:IPR001452(Src homology-3)|interpro:IPR008079(Voltage-dependent calcium channel, L-type, beta-3 subunit)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR027417|interpro:IPR035760|interpro:IPR036028|reactome:R-HSA-112308|reactome:R-HSA-400042|reactome:R-HSA-419037|reactome:R-HSA-422356|go:"GO:0090314"(positive regulation of protein targeting to membrane)|go:"GO:0090650"(cellular response to oxygen-glucose deprivation)|go:"GO:0098903"(regulation of membrane repolarization during action potential)|go:"GO:1901385"(regulation of voltage-gated calcium channel activity)|go:"GO:1901386"(negative regulation of voltage-gated calcium channel activity)|go:"GO:1901843"(positive regulation of high voltage-gated calcium channel activity)|go:"GO:1902630"(regulation of membrane hyperpolarization)|go:"GO:1905788"(negative regulation of detection of mechanical stimulus involved in sensory perception of touch)|go:"GO:1990454"(L-type voltage-gated calcium channel complex)|go:"GO:2000463"(positive regulation of excitatory postsynaptic potential)|interpro:IPR000584(Voltage-dependent calcium channel, L-type, beta subunit)|refseq:NP_001193844.1|refseq:NP_001193845.1|refseq:NP_001193846.1|dip:DIP-39138N refseq:NP_000710.5|refseq:NP_001123299.1|refseq:NP_001123301.1|refseq:NP_001123303.1|refseq:NP_001123304.1|refseq:NP_001123305.1|refseq:NP_001123306.1|refseq:NP_001123307.1|refseq:NP_001123314.1|refseq:NP_001123315.1|refseq:NP_001123308.1|refseq:NP_001123309.1|refseq:NP_001123310.1|refseq:NP_001123311.1|refseq:NP_001123312.1|refseq:NP_001123313.1|refseq:NP_001123316.1|refseq:NP_001123318.1|refseq:NP_001161095.1|refseq:NP_001161097.1|refseq:NP_001123302.2|refseq:NP_001161096.2|refseq:NP_955630.3|reactome:R-HSA-5576893|reactome:R-HSA-400042|reactome:R-HSA-419037|reactome:R-HSA-422356|go:"GO:0002520"(immune system development)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007507"(heart development)|go:"GO:0008331"(high voltage-gated calcium channel activity)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030018"(Z disc)|go:"GO:0030425"(dendrite)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035585"(calcium-mediated signaling using extracellular calcium source)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043204"(perikaryon)|go:"GO:0045762"(positive regulation of adenylate cyclase activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0051393"(alpha-actinin binding)|go:"GO:0060402"(calcium ion transport into cytosol)|go:"GO:0061337"(cardiac conduction)|go:"GO:0061577"(calcium ion transmembrane transport via high voltage-gated calcium channel)|go:"GO:0070509"(calcium ion import)|go:"GO:0086002"(cardiac muscle cell action potential involved in contraction)|go:"GO:0086007"(voltage-gated calcium channel activity involved in cardiac muscle cell action potential)|go:"GO:0086012"(membrane depolarization during cardiac muscle cell action potential)|go:"GO:0086045"(membrane depolarization during AV node cell action potential)|go:"GO:0086056"(voltage-gated calcium channel activity involved in AV node cell action potential)|go:"GO:0086064"(cell communication by electrical coupling involved in cardiac conduction)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|go:"GO:0098912"(membrane depolarization during atrial cardiac muscle cell action potential)|go:"GO:1990454"(L-type voltage-gated calcium channel complex)|interpro:IPR002077(Voltage-dependent calcium channel, alpha-1 subunit)|interpro:IPR005446(Voltage-dependent calcium channel, L-type, alpha-1 subunit)|interpro:IPR005451(Voltage-dependent calcium channel, L-type, alpha-1C subunit)|interpro:IPR005821(Ion transport)|interpro:IPR014873(Voltage-dependent calcium channel, alpha-1 subunit, IQ domain)|interpro:IPR027359|interpro:IPR031649|interpro:IPR031688|rcsb pdb:1T0J|rcsb pdb:2BE6|rcsb pdb:2F3Y|rcsb pdb:2F3Z|rcsb pdb:2LQC|rcsb pdb:3G43|rcsb pdb:3OXQ|rcsb pdb:5V2P|rcsb pdb:5V2Q|rcsb pdb:6C0A|rcsb pdb:6DAD|rcsb pdb:6DAE|rcsb pdb:6DAF|rcsb pdb:6U39|rcsb pdb:6U3A|rcsb pdb:6U3B|rcsb pdb:6U3D|go:"GO:0070588"(calcium ion transmembrane transport)|reactome:R-HSA-5576892|dip:DIP-29589N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9534(chlae)|taxid:9534(Chlorocebus aethiops) - 2017/08/05 2019/04/16 rogid:UTOg/TyylvvNXDm9Yt7LvIx47049606 rogid:dhWcWUTulWYd/nQtGorjr481/XA9606 rigid:KbCFxiS5ELLmYnEUizjGBSW87Oo false - flag tag:n-n - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q02641-1 uniprotkb:Q13936 intact:EBI-15707950|ensembl:ENSP00000377840 intact:EBI-1038838|uniprotkb:Q13917|uniprotkb:Q13918|uniprotkb:Q13919|uniprotkb:Q13920|uniprotkb:Q13921|uniprotkb:Q13922|uniprotkb:Q13923|uniprotkb:Q13924|uniprotkb:Q13925|uniprotkb:Q13926|uniprotkb:Q13927|uniprotkb:Q13928|uniprotkb:Q13929|uniprotkb:Q13930|uniprotkb:Q13932|uniprotkb:Q13933|uniprotkb:Q14743|uniprotkb:Q14744|uniprotkb:Q15877|uniprotkb:Q4VMI7|uniprotkb:Q4VMI8|uniprotkb:Q4VMI9|uniprotkb:Q6PKM7|uniprotkb:Q8N6C0|uniprotkb:Q99025|uniprotkb:Q99241|uniprotkb:Q99875|uniprotkb:B2RUT3|uniprotkb:E9PDJ0 psi-mi:q02641-1(display_long)|uniprotkb:CACNB1(gene name)|psi-mi:CACNB1(display_short)|uniprotkb:CACNLB1(gene name synonym)|uniprotkb:Calcium channel voltage-dependent subunit beta 1(gene name synonym)|uniprotkb:Beta-1B(isoform synonym)|uniprotkb:Beta-1b2(isoform synonym)|uniprotkb:Beta1-2(isoform synonym)|uniprotkb:BetaA(isoform synonym) psi-mi:cac1c_human(display_long)|uniprotkb:CACNA1C(gene name)|psi-mi:CACNA1C(display_short)|uniprotkb:CACH2(gene name synonym)|uniprotkb:CACN2(gene name synonym)|uniprotkb:CACNL1A1(gene name synonym)|uniprotkb:CCHL1A1(gene name synonym)|uniprotkb:Voltage-gated calcium channel subunit alpha Cav1.2(gene name synonym)|uniprotkb:Calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ravindran et al. (2008) pubmed:18535142|doi:10.1073/pnas.0711624105|imex:IM-9366 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15707961|imex:IM-9366-1|dip:DIP-87915E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-947514(isoform-parent)|ensembl:ENSG00000067191(gene)|ensembl:ENST00000394303(transcript) refseq:NP_000710.5|refseq:NP_001123299.1|refseq:NP_001123301.1|refseq:NP_001123303.1|refseq:NP_001123304.1|refseq:NP_001123305.1|refseq:NP_001123306.1|refseq:NP_001123307.1|refseq:NP_001123314.1|refseq:NP_001123315.1|refseq:NP_001123308.1|refseq:NP_001123309.1|refseq:NP_001123310.1|refseq:NP_001123311.1|refseq:NP_001123312.1|refseq:NP_001123313.1|refseq:NP_001123316.1|refseq:NP_001123318.1|refseq:NP_001161095.1|refseq:NP_001161097.1|refseq:NP_001123302.2|refseq:NP_001161096.2|refseq:NP_955630.3|reactome:R-HSA-5576893|reactome:R-HSA-400042|reactome:R-HSA-419037|reactome:R-HSA-422356|go:"GO:0002520"(immune system development)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007507"(heart development)|go:"GO:0008331"(high voltage-gated calcium channel activity)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030018"(Z disc)|go:"GO:0030425"(dendrite)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035585"(calcium-mediated signaling using extracellular calcium source)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043204"(perikaryon)|go:"GO:0045762"(positive regulation of adenylate cyclase activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0051393"(alpha-actinin binding)|go:"GO:0060402"(calcium ion transport into cytosol)|go:"GO:0061337"(cardiac conduction)|go:"GO:0061577"(calcium ion transmembrane transport via high voltage-gated calcium channel)|go:"GO:0070509"(calcium ion import)|go:"GO:0086002"(cardiac muscle cell action potential involved in contraction)|go:"GO:0086007"(voltage-gated calcium channel activity involved in cardiac muscle cell action potential)|go:"GO:0086012"(membrane depolarization during cardiac muscle cell action potential)|go:"GO:0086045"(membrane depolarization during AV node cell action potential)|go:"GO:0086056"(voltage-gated calcium channel activity involved in AV node cell action potential)|go:"GO:0086064"(cell communication by electrical coupling involved in cardiac conduction)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|go:"GO:0098912"(membrane depolarization during atrial cardiac muscle cell action potential)|go:"GO:1990454"(L-type voltage-gated calcium channel complex)|interpro:IPR002077(Voltage-dependent calcium channel, alpha-1 subunit)|interpro:IPR005446(Voltage-dependent calcium channel, L-type, alpha-1 subunit)|interpro:IPR005451(Voltage-dependent calcium channel, L-type, alpha-1C subunit)|interpro:IPR005821(Ion transport)|interpro:IPR014873(Voltage-dependent calcium channel, alpha-1 subunit, IQ domain)|interpro:IPR027359|interpro:IPR031649|interpro:IPR031688|rcsb pdb:1T0J|rcsb pdb:2BE6|rcsb pdb:2F3Y|rcsb pdb:2F3Z|rcsb pdb:2LQC|rcsb pdb:3G43|rcsb pdb:3OXQ|rcsb pdb:5V2P|rcsb pdb:5V2Q|rcsb pdb:6C0A|rcsb pdb:6DAD|rcsb pdb:6DAE|rcsb pdb:6DAF|rcsb pdb:6U39|rcsb pdb:6U3A|rcsb pdb:6U3B|rcsb pdb:6U3D|go:"GO:0070588"(calcium ion transmembrane transport)|reactome:R-HSA-5576892|dip:DIP-29589N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9534(chlae)|taxid:9534(Chlorocebus aethiops) - 2017/08/05 2019/04/16 rogid:nP0QYe6Gr+aIneTmyLWfPuvMEfk9606 rogid:dhWcWUTulWYd/nQtGorjr481/XA9606 rigid:3nGOm7lRHNs54UfFR/QRpmb8sEA false - flag tag:n-n - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q13936 uniprotkb:Q08289-1 intact:EBI-1038838|uniprotkb:Q13917|uniprotkb:Q13918|uniprotkb:Q13919|uniprotkb:Q13920|uniprotkb:Q13921|uniprotkb:Q13922|uniprotkb:Q13923|uniprotkb:Q13924|uniprotkb:Q13925|uniprotkb:Q13926|uniprotkb:Q13927|uniprotkb:Q13928|uniprotkb:Q13929|uniprotkb:Q13930|uniprotkb:Q13932|uniprotkb:Q13933|uniprotkb:Q14743|uniprotkb:Q14744|uniprotkb:Q15877|uniprotkb:Q4VMI7|uniprotkb:Q4VMI8|uniprotkb:Q4VMI9|uniprotkb:Q6PKM7|uniprotkb:Q8N6C0|uniprotkb:Q99025|uniprotkb:Q99241|uniprotkb:Q99875|uniprotkb:B2RUT3|uniprotkb:E9PDJ0 intact:EBI-15707999|ensembl:ENSP00000320025 psi-mi:cac1c_human(display_long)|uniprotkb:CACNA1C(gene name)|psi-mi:CACNA1C(display_short)|uniprotkb:CACH2(gene name synonym)|uniprotkb:CACN2(gene name synonym)|uniprotkb:CACNL1A1(gene name synonym)|uniprotkb:CCHL1A1(gene name synonym)|uniprotkb:Voltage-gated calcium channel subunit alpha Cav1.2(gene name synonym)|uniprotkb:Calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle(gene name synonym) psi-mi:q08289-1(display_long)|uniprotkb:CACNB2(gene name)|psi-mi:CACNB2(display_short)|uniprotkb:CACNLB2(gene name synonym)|uniprotkb:MYSB(gene name synonym)|uniprotkb:CACNB2d(isoform synonym)|uniprotkb:Calcium channel voltage-dependent subunit beta 2(gene name synonym)|uniprotkb:Lambert-Eaton myasthenic syndrome antigen B(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ravindran et al. (2008) pubmed:18535142|doi:10.1073/pnas.0711624105|imex:IM-9366 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15708096|imex:IM-9366-7|dip:DIP-87913E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000710.5|refseq:NP_001123299.1|refseq:NP_001123301.1|refseq:NP_001123303.1|refseq:NP_001123304.1|refseq:NP_001123305.1|refseq:NP_001123306.1|refseq:NP_001123307.1|refseq:NP_001123314.1|refseq:NP_001123315.1|refseq:NP_001123308.1|refseq:NP_001123309.1|refseq:NP_001123310.1|refseq:NP_001123311.1|refseq:NP_001123312.1|refseq:NP_001123313.1|refseq:NP_001123316.1|refseq:NP_001123318.1|refseq:NP_001161095.1|refseq:NP_001161097.1|refseq:NP_001123302.2|refseq:NP_001161096.2|refseq:NP_955630.3|reactome:R-HSA-5576893|reactome:R-HSA-400042|reactome:R-HSA-419037|reactome:R-HSA-422356|go:"GO:0002520"(immune system development)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007507"(heart development)|go:"GO:0008331"(high voltage-gated calcium channel activity)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030018"(Z disc)|go:"GO:0030425"(dendrite)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035585"(calcium-mediated signaling using extracellular calcium source)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043204"(perikaryon)|go:"GO:0045762"(positive regulation of adenylate cyclase activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0051393"(alpha-actinin binding)|go:"GO:0060402"(calcium ion transport into cytosol)|go:"GO:0061337"(cardiac conduction)|go:"GO:0061577"(calcium ion transmembrane transport via high voltage-gated calcium channel)|go:"GO:0070509"(calcium ion import)|go:"GO:0086002"(cardiac muscle cell action potential involved in contraction)|go:"GO:0086007"(voltage-gated calcium channel activity involved in cardiac muscle cell action potential)|go:"GO:0086012"(membrane depolarization during cardiac muscle cell action potential)|go:"GO:0086045"(membrane depolarization during AV node cell action potential)|go:"GO:0086056"(voltage-gated calcium channel activity involved in AV node cell action potential)|go:"GO:0086064"(cell communication by electrical coupling involved in cardiac conduction)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|go:"GO:0098912"(membrane depolarization during atrial cardiac muscle cell action potential)|go:"GO:1990454"(L-type voltage-gated calcium channel complex)|interpro:IPR002077(Voltage-dependent calcium channel, alpha-1 subunit)|interpro:IPR005446(Voltage-dependent calcium channel, L-type, alpha-1 subunit)|interpro:IPR005451(Voltage-dependent calcium channel, L-type, alpha-1C subunit)|interpro:IPR005821(Ion transport)|interpro:IPR014873(Voltage-dependent calcium channel, alpha-1 subunit, IQ domain)|interpro:IPR027359|interpro:IPR031649|interpro:IPR031688|rcsb pdb:1T0J|rcsb pdb:2BE6|rcsb pdb:2F3Y|rcsb pdb:2F3Z|rcsb pdb:2LQC|rcsb pdb:3G43|rcsb pdb:3OXQ|rcsb pdb:5V2P|rcsb pdb:5V2Q|rcsb pdb:6C0A|rcsb pdb:6DAD|rcsb pdb:6DAE|rcsb pdb:6DAF|rcsb pdb:6U39|rcsb pdb:6U3A|rcsb pdb:6U3B|rcsb pdb:6U3D|go:"GO:0070588"(calcium ion transmembrane transport)|reactome:R-HSA-5576892|dip:DIP-29589N ensembl:ENSG00000165995(gene)|ensembl:ENST00000324631(transcript)|intact:EBI-2874501(isoform-parent) psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9534(chlae)|taxid:9534(Chlorocebus aethiops) - 2017/08/05 2019/04/16 rogid:dhWcWUTulWYd/nQtGorjr481/XA9606 rogid:62aD9Wbg0RTCIwNCGexJvVgKkGE9606 rigid:r6cIsUDzOA8pL9P1O1RVo3ATZzM false flag tag:n-n - - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P62161 uniprotkb:Q13936 intact:EBI-397530|uniprotkb:P02593|uniprotkb:P70667|uniprotkb:P99014|uniprotkb:Q61379|uniprotkb:Q61380|dip:DIP-29528N|refseq:NP_059022|uniprotkb:P0DP30 intact:EBI-1038838|uniprotkb:Q13917|uniprotkb:Q13918|uniprotkb:Q13919|uniprotkb:Q13920|uniprotkb:Q13921|uniprotkb:Q13922|uniprotkb:Q13923|uniprotkb:Q13924|uniprotkb:Q13925|uniprotkb:Q13926|uniprotkb:Q13927|uniprotkb:Q13928|uniprotkb:Q13929|uniprotkb:Q13930|uniprotkb:Q13932|uniprotkb:Q13933|uniprotkb:Q14743|uniprotkb:Q14744|uniprotkb:Q15877|uniprotkb:Q4VMI7|uniprotkb:Q4VMI8|uniprotkb:Q4VMI9|uniprotkb:Q6PKM7|uniprotkb:Q8N6C0|uniprotkb:Q99025|uniprotkb:Q99241|uniprotkb:Q99875|uniprotkb:B2RUT3|uniprotkb:E9PDJ0 psi-mi:calm_rat(display_long)|uniprotkb:Calm1(gene name)|psi-mi:Calm1(display_short)|uniprotkb:Calm(gene name synonym)|uniprotkb:Cam(gene name synonym)|uniprotkb:Cam1(gene name synonym)|uniprotkb:Calm2(gene name)|psi-mi:Calm2(display_short)|uniprotkb:Cam2(gene name synonym)|uniprotkb:Camb(gene name synonym)|uniprotkb:Calm3(gene name)|psi-mi:Calm3(display_short)|uniprotkb:Cam3(gene name synonym)|uniprotkb:Camc(gene name synonym)|uniprotkb:CaMII(gene name synonym) psi-mi:cac1c_human(display_long)|uniprotkb:CACNA1C(gene name)|psi-mi:CACNA1C(display_short)|uniprotkb:CACH2(gene name synonym)|uniprotkb:CACN2(gene name synonym)|uniprotkb:CACNL1A1(gene name synonym)|uniprotkb:CCHL1A1(gene name synonym)|uniprotkb:Voltage-gated calcium channel subunit alpha Cav1.2(gene name synonym)|uniprotkb:Calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ravindran et al. (2008) pubmed:18535142|doi:10.1073/pnas.0711624105|imex:IM-9366 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15708115|imex:IM-9366-8|dip:DIP-87914E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:4G27|rcsb pdb:4G28|go:"GO:0030426"(growth cone)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051000"(positive regulation of nitric-oxide synthase activity)|go:"GO:0060314"(regulation of ryanodine-sensitive calcium-release channel activity)|go:"GO:1901339"(regulation of store-operated calcium channel activity)|go:"GO:1901841"(regulation of high voltage-gated calcium channel activity)|rcsb pdb:4I2Y|rcsb pdb:4IL1|go:"GO:0007190"(activation of adenylate cyclase activity)|go:"GO:0008179"(adenylate cyclase binding)|go:"GO:0019722"(calcium-mediated signaling)|go:"GO:0030235"(nitric-oxide synthase regulator activity)|rcsb pdb:4RJD|go:"GO:0000922"(spindle pole)|go:"GO:0005246"(calcium channel regulator activity)|rgd:2257|rgd:2258|rgd:2259|refseq:NP_036650.1|refseq:NP_059022.1|refseq:NP_114175.1|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR002048(Calcium-binding EF-hand)|rcsb pdb:1G4Y|rcsb pdb:1NIW|rcsb pdb:1QX5|rcsb pdb:1QX7|rcsb pdb:2HQW|rcsb pdb:2PQ3|rcsb pdb:3B32|rcsb pdb:3BXK|rcsb pdb:3BXL|rcsb pdb:3CLN|rcsb pdb:3EK4|rcsb pdb:3EK7|rcsb pdb:3EK8|rcsb pdb:3EKH|rcsb pdb:3EKJ|rcsb pdb:3EVR|rcsb pdb:3EVU|rcsb pdb:3EVV|rcsb pdb:3IFK|rcsb pdb:3SG2|rcsb pdb:3SG3|rcsb pdb:3SG4|rcsb pdb:3SG5|rcsb pdb:3SG6|rcsb pdb:3SG7|rcsb pdb:3SJQ|rcsb pdb:4QNH|go:"GO:0005509"(calcium ion binding)|reactome:R-RNO-2672351|reactome:R-RNO-418359|reactome:R-RNO-425561|reactome:R-RNO-5576892|reactome:R-RNO-5578775|reactome:R-RNO-936837|rcsb pdb:4OY4|go:"GO:0005829"(cytosol)|rcsb pdb:2YGG|go:"GO:0005886"(plasma membrane)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005513"(detection of calcium ion)|go:"GO:0005813"(centrosome)|go:"GO:0005876"(spindle microtubule)|go:"GO:0010880"(regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0021762"(substantia nigra development)|go:"GO:0030017"(sarcomere)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0032516"(positive regulation of phosphoprotein phosphatase activity)|go:"GO:0034704"(calcium channel complex)|go:"GO:0051343"(positive regulation of cyclic-nucleotide phosphodiesterase activity)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060316"(positive regulation of ryanodine-sensitive calcium-release channel activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072542"(protein phosphatase activator activity)|go:"GO:0014069"(postsynaptic density)|go:"GO:0099566"(regulation of postsynaptic cytosolic calcium ion concentration)|reactome:R-RNO-8876725|go:"GO:0001975"(response to amphetamine)|go:"GO:0051412"(response to corticosterone)|rcsb pdb:4EHQ|rcsb pdb:4J9Y|rcsb pdb:4J9Z|reactome:R-RNO-163615|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0031800"(type 3 metabotropic glutamate receptor binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0048306"(calcium-dependent protein binding)|rcsb pdb:2MGU|ensembl:ENSRNOT00000022603|ensembl:ENSRNOT00000064679|rcsb pdb:3WLC|rcsb pdb:3WLD|reactome:R-RNO-111932|reactome:R-RNO-111933|reactome:R-RNO-111957|reactome:R-RNO-114608|reactome:R-RNO-1474151|reactome:R-RNO-1855204|reactome:R-RNO-203615|reactome:R-RNO-2514859|reactome:R-RNO-2871809|reactome:R-RNO-4086398|reactome:R-RNO-442717|reactome:R-RNO-442729|reactome:R-RNO-442745|reactome:R-RNO-442982|reactome:R-RNO-445355|reactome:R-RNO-451308|reactome:R-RNO-5218920|reactome:R-RNO-5607763|reactome:R-RNO-5626467|reactome:R-RNO-5627123|reactome:R-RNO-5673001|reactome:R-RNO-70221|ensembl:ENSRNOG00000004060|ensembl:ENSRNOG00000016770|ensembl:ENSRNOP00000022603|ensembl:ENSRNOP00000063822|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0019855"(calcium channel inhibitor activity)|go:"GO:0060315"(negative regulation of ryanodine-sensitive calcium-release channel activity) refseq:NP_000710.5|refseq:NP_001123299.1|refseq:NP_001123301.1|refseq:NP_001123303.1|refseq:NP_001123304.1|refseq:NP_001123305.1|refseq:NP_001123306.1|refseq:NP_001123307.1|refseq:NP_001123314.1|refseq:NP_001123315.1|refseq:NP_001123308.1|refseq:NP_001123309.1|refseq:NP_001123310.1|refseq:NP_001123311.1|refseq:NP_001123312.1|refseq:NP_001123313.1|refseq:NP_001123316.1|refseq:NP_001123318.1|refseq:NP_001161095.1|refseq:NP_001161097.1|refseq:NP_001123302.2|refseq:NP_001161096.2|refseq:NP_955630.3|reactome:R-HSA-5576893|reactome:R-HSA-400042|reactome:R-HSA-419037|reactome:R-HSA-422356|go:"GO:0002520"(immune system development)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007507"(heart development)|go:"GO:0008331"(high voltage-gated calcium channel activity)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030018"(Z disc)|go:"GO:0030425"(dendrite)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035585"(calcium-mediated signaling using extracellular calcium source)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043204"(perikaryon)|go:"GO:0045762"(positive regulation of adenylate cyclase activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0051393"(alpha-actinin binding)|go:"GO:0060402"(calcium ion transport into cytosol)|go:"GO:0061337"(cardiac conduction)|go:"GO:0061577"(calcium ion transmembrane transport via high voltage-gated calcium channel)|go:"GO:0070509"(calcium ion import)|go:"GO:0086002"(cardiac muscle cell action potential involved in contraction)|go:"GO:0086007"(voltage-gated calcium channel activity involved in cardiac muscle cell action potential)|go:"GO:0086012"(membrane depolarization during cardiac muscle cell action potential)|go:"GO:0086045"(membrane depolarization during AV node cell action potential)|go:"GO:0086056"(voltage-gated calcium channel activity involved in AV node cell action potential)|go:"GO:0086064"(cell communication by electrical coupling involved in cardiac conduction)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|go:"GO:0098912"(membrane depolarization during atrial cardiac muscle cell action potential)|go:"GO:1990454"(L-type voltage-gated calcium channel complex)|interpro:IPR002077(Voltage-dependent calcium channel, alpha-1 subunit)|interpro:IPR005446(Voltage-dependent calcium channel, L-type, alpha-1 subunit)|interpro:IPR005451(Voltage-dependent calcium channel, L-type, alpha-1C subunit)|interpro:IPR005821(Ion transport)|interpro:IPR014873(Voltage-dependent calcium channel, alpha-1 subunit, IQ domain)|interpro:IPR027359|interpro:IPR031649|interpro:IPR031688|rcsb pdb:1T0J|rcsb pdb:2BE6|rcsb pdb:2F3Y|rcsb pdb:2F3Z|rcsb pdb:2LQC|rcsb pdb:3G43|rcsb pdb:3OXQ|rcsb pdb:5V2P|rcsb pdb:5V2Q|rcsb pdb:6C0A|rcsb pdb:6DAD|rcsb pdb:6DAE|rcsb pdb:6DAF|rcsb pdb:6U39|rcsb pdb:6U3A|rcsb pdb:6U3B|rcsb pdb:6U3D|go:"GO:0070588"(calcium ion transmembrane transport)|reactome:R-HSA-5576892|dip:DIP-29589N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9534(chlae)|taxid:9534(Chlorocebus aethiops) - 2017/08/05 2019/04/16 rogid:tTYcOd9bOh211njZVz7cYVybAMQ10116 rogid:dhWcWUTulWYd/nQtGorjr481/XA9606 rigid:D3NEoSVMDlEnRa5peTH5k+i8Zic false cyan fluorescent protein tag:0-0 flag tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P54284 uniprotkb:Q13936 intact:EBI-1184651|uniprotkb:Q13913|uniprotkb:A8K0Z4|ensembl:ENSP00000301050|uniprotkb:B7Z4Q1|uniprotkb:B7Z973|uniprotkb:B7ZAK8|uniprotkb:F5GZW7|uniprotkb:F5H2P6|uniprotkb:F8VSG3 intact:EBI-1038838|uniprotkb:Q13917|uniprotkb:Q13918|uniprotkb:Q13919|uniprotkb:Q13920|uniprotkb:Q13921|uniprotkb:Q13922|uniprotkb:Q13923|uniprotkb:Q13924|uniprotkb:Q13925|uniprotkb:Q13926|uniprotkb:Q13927|uniprotkb:Q13928|uniprotkb:Q13929|uniprotkb:Q13930|uniprotkb:Q13932|uniprotkb:Q13933|uniprotkb:Q14743|uniprotkb:Q14744|uniprotkb:Q15877|uniprotkb:Q4VMI7|uniprotkb:Q4VMI8|uniprotkb:Q4VMI9|uniprotkb:Q6PKM7|uniprotkb:Q8N6C0|uniprotkb:Q99025|uniprotkb:Q99241|uniprotkb:Q99875|uniprotkb:B2RUT3|uniprotkb:E9PDJ0 psi-mi:cacb3_human(display_long)|uniprotkb:CACNB3(gene name)|psi-mi:CACNB3(display_short)|uniprotkb:CACNLB3(gene name synonym)|uniprotkb:Calcium channel voltage-dependent subunit beta 3(gene name synonym) psi-mi:cac1c_human(display_long)|uniprotkb:CACNA1C(gene name)|psi-mi:CACNA1C(display_short)|uniprotkb:CACH2(gene name synonym)|uniprotkb:CACN2(gene name synonym)|uniprotkb:CACNL1A1(gene name synonym)|uniprotkb:CCHL1A1(gene name synonym)|uniprotkb:Voltage-gated calcium channel subunit alpha Cav1.2(gene name synonym)|uniprotkb:Calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ravindran et al. (2008) pubmed:18535142|doi:10.1073/pnas.0711624105|imex:IM-9366 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15708137|imex:IM-9366-9|dip:DIP-87916E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000716.2|ensembl:ENSG00000167535(gene)|ensembl:ENST00000301050(transcript)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005829"(cytosol)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0008331"(high voltage-gated calcium channel activity)|go:"GO:0016020"(membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0045202"(synapse)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050966"(detection of mechanical stimulus involved in sensory perception of pain)|go:"GO:0060402"(calcium ion transport into cytosol)|go:"GO:0061577"(calcium ion transmembrane transport via high voltage-gated calcium channel)|go:"GO:0072659"(protein localization to plasma membrane)|interpro:IPR001452(Src homology-3)|interpro:IPR008079(Voltage-dependent calcium channel, L-type, beta-3 subunit)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR027417|interpro:IPR035760|interpro:IPR036028|reactome:R-HSA-112308|reactome:R-HSA-400042|reactome:R-HSA-419037|reactome:R-HSA-422356|go:"GO:0090314"(positive regulation of protein targeting to membrane)|go:"GO:0090650"(cellular response to oxygen-glucose deprivation)|go:"GO:0098903"(regulation of membrane repolarization during action potential)|go:"GO:1901385"(regulation of voltage-gated calcium channel activity)|go:"GO:1901386"(negative regulation of voltage-gated calcium channel activity)|go:"GO:1901843"(positive regulation of high voltage-gated calcium channel activity)|go:"GO:1902630"(regulation of membrane hyperpolarization)|go:"GO:1905788"(negative regulation of detection of mechanical stimulus involved in sensory perception of touch)|go:"GO:1990454"(L-type voltage-gated calcium channel complex)|go:"GO:2000463"(positive regulation of excitatory postsynaptic potential)|interpro:IPR000584(Voltage-dependent calcium channel, L-type, beta subunit)|refseq:NP_001193844.1|refseq:NP_001193845.1|refseq:NP_001193846.1|dip:DIP-39138N refseq:NP_000710.5|refseq:NP_001123299.1|refseq:NP_001123301.1|refseq:NP_001123303.1|refseq:NP_001123304.1|refseq:NP_001123305.1|refseq:NP_001123306.1|refseq:NP_001123307.1|refseq:NP_001123314.1|refseq:NP_001123315.1|refseq:NP_001123308.1|refseq:NP_001123309.1|refseq:NP_001123310.1|refseq:NP_001123311.1|refseq:NP_001123312.1|refseq:NP_001123313.1|refseq:NP_001123316.1|refseq:NP_001123318.1|refseq:NP_001161095.1|refseq:NP_001161097.1|refseq:NP_001123302.2|refseq:NP_001161096.2|refseq:NP_955630.3|reactome:R-HSA-5576893|reactome:R-HSA-400042|reactome:R-HSA-419037|reactome:R-HSA-422356|go:"GO:0002520"(immune system development)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007507"(heart development)|go:"GO:0008331"(high voltage-gated calcium channel activity)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030018"(Z disc)|go:"GO:0030425"(dendrite)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035585"(calcium-mediated signaling using extracellular calcium source)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043204"(perikaryon)|go:"GO:0045762"(positive regulation of adenylate cyclase activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0051393"(alpha-actinin binding)|go:"GO:0060402"(calcium ion transport into cytosol)|go:"GO:0061337"(cardiac conduction)|go:"GO:0061577"(calcium ion transmembrane transport via high voltage-gated calcium channel)|go:"GO:0070509"(calcium ion import)|go:"GO:0086002"(cardiac muscle cell action potential involved in contraction)|go:"GO:0086007"(voltage-gated calcium channel activity involved in cardiac muscle cell action potential)|go:"GO:0086012"(membrane depolarization during cardiac muscle cell action potential)|go:"GO:0086045"(membrane depolarization during AV node cell action potential)|go:"GO:0086056"(voltage-gated calcium channel activity involved in AV node cell action potential)|go:"GO:0086064"(cell communication by electrical coupling involved in cardiac conduction)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|go:"GO:0098912"(membrane depolarization during atrial cardiac muscle cell action potential)|go:"GO:1990454"(L-type voltage-gated calcium channel complex)|interpro:IPR002077(Voltage-dependent calcium channel, alpha-1 subunit)|interpro:IPR005446(Voltage-dependent calcium channel, L-type, alpha-1 subunit)|interpro:IPR005451(Voltage-dependent calcium channel, L-type, alpha-1C subunit)|interpro:IPR005821(Ion transport)|interpro:IPR014873(Voltage-dependent calcium channel, alpha-1 subunit, IQ domain)|interpro:IPR027359|interpro:IPR031649|interpro:IPR031688|rcsb pdb:1T0J|rcsb pdb:2BE6|rcsb pdb:2F3Y|rcsb pdb:2F3Z|rcsb pdb:2LQC|rcsb pdb:3G43|rcsb pdb:3OXQ|rcsb pdb:5V2P|rcsb pdb:5V2Q|rcsb pdb:6C0A|rcsb pdb:6DAD|rcsb pdb:6DAE|rcsb pdb:6DAF|rcsb pdb:6U39|rcsb pdb:6U3A|rcsb pdb:6U3B|rcsb pdb:6U3D|go:"GO:0070588"(calcium ion transmembrane transport)|reactome:R-HSA-5576892|dip:DIP-29589N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9534(chlae)|taxid:9534(Chlorocebus aethiops) - 2017/08/05 2019/04/16 rogid:UTOg/TyylvvNXDm9Yt7LvIx47049606 rogid:dhWcWUTulWYd/nQtGorjr481/XA9606 rigid:KbCFxiS5ELLmYnEUizjGBSW87Oo false - flag tag:n-n - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P62161 uniprotkb:Q13936 intact:EBI-397530|uniprotkb:P02593|uniprotkb:P70667|uniprotkb:P99014|uniprotkb:Q61379|uniprotkb:Q61380|dip:DIP-29528N|refseq:NP_059022|uniprotkb:P0DP30 intact:EBI-1038838|uniprotkb:Q13917|uniprotkb:Q13918|uniprotkb:Q13919|uniprotkb:Q13920|uniprotkb:Q13921|uniprotkb:Q13922|uniprotkb:Q13923|uniprotkb:Q13924|uniprotkb:Q13925|uniprotkb:Q13926|uniprotkb:Q13927|uniprotkb:Q13928|uniprotkb:Q13929|uniprotkb:Q13930|uniprotkb:Q13932|uniprotkb:Q13933|uniprotkb:Q14743|uniprotkb:Q14744|uniprotkb:Q15877|uniprotkb:Q4VMI7|uniprotkb:Q4VMI8|uniprotkb:Q4VMI9|uniprotkb:Q6PKM7|uniprotkb:Q8N6C0|uniprotkb:Q99025|uniprotkb:Q99241|uniprotkb:Q99875|uniprotkb:B2RUT3|uniprotkb:E9PDJ0 psi-mi:calm_rat(display_long)|uniprotkb:Calm1(gene name)|psi-mi:Calm1(display_short)|uniprotkb:Calm(gene name synonym)|uniprotkb:Cam(gene name synonym)|uniprotkb:Cam1(gene name synonym)|uniprotkb:Calm2(gene name)|psi-mi:Calm2(display_short)|uniprotkb:Cam2(gene name synonym)|uniprotkb:Camb(gene name synonym)|uniprotkb:Calm3(gene name)|psi-mi:Calm3(display_short)|uniprotkb:Cam3(gene name synonym)|uniprotkb:Camc(gene name synonym)|uniprotkb:CaMII(gene name synonym) psi-mi:cac1c_human(display_long)|uniprotkb:CACNA1C(gene name)|psi-mi:CACNA1C(display_short)|uniprotkb:CACH2(gene name synonym)|uniprotkb:CACN2(gene name synonym)|uniprotkb:CACNL1A1(gene name synonym)|uniprotkb:CCHL1A1(gene name synonym)|uniprotkb:Voltage-gated calcium channel subunit alpha Cav1.2(gene name synonym)|uniprotkb:Calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ravindran et al. (2008) pubmed:18535142|doi:10.1073/pnas.0711624105|imex:IM-9366 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15708074|imex:IM-9366-6|dip:DIP-87914E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:4G27|rcsb pdb:4G28|go:"GO:0030426"(growth cone)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051000"(positive regulation of nitric-oxide synthase activity)|go:"GO:0060314"(regulation of ryanodine-sensitive calcium-release channel activity)|go:"GO:1901339"(regulation of store-operated calcium channel activity)|go:"GO:1901841"(regulation of high voltage-gated calcium channel activity)|rcsb pdb:4I2Y|rcsb pdb:4IL1|go:"GO:0007190"(activation of adenylate cyclase activity)|go:"GO:0008179"(adenylate cyclase binding)|go:"GO:0019722"(calcium-mediated signaling)|go:"GO:0030235"(nitric-oxide synthase regulator activity)|rcsb pdb:4RJD|go:"GO:0000922"(spindle pole)|go:"GO:0005246"(calcium channel regulator activity)|rgd:2257|rgd:2258|rgd:2259|refseq:NP_036650.1|refseq:NP_059022.1|refseq:NP_114175.1|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR002048(Calcium-binding EF-hand)|rcsb pdb:1G4Y|rcsb pdb:1NIW|rcsb pdb:1QX5|rcsb pdb:1QX7|rcsb pdb:2HQW|rcsb pdb:2PQ3|rcsb pdb:3B32|rcsb pdb:3BXK|rcsb pdb:3BXL|rcsb pdb:3CLN|rcsb pdb:3EK4|rcsb pdb:3EK7|rcsb pdb:3EK8|rcsb pdb:3EKH|rcsb pdb:3EKJ|rcsb pdb:3EVR|rcsb pdb:3EVU|rcsb pdb:3EVV|rcsb pdb:3IFK|rcsb pdb:3SG2|rcsb pdb:3SG3|rcsb pdb:3SG4|rcsb pdb:3SG5|rcsb pdb:3SG6|rcsb pdb:3SG7|rcsb pdb:3SJQ|rcsb pdb:4QNH|go:"GO:0005509"(calcium ion binding)|reactome:R-RNO-2672351|reactome:R-RNO-418359|reactome:R-RNO-425561|reactome:R-RNO-5576892|reactome:R-RNO-5578775|reactome:R-RNO-936837|rcsb pdb:4OY4|go:"GO:0005829"(cytosol)|rcsb pdb:2YGG|go:"GO:0005886"(plasma membrane)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005513"(detection of calcium ion)|go:"GO:0005813"(centrosome)|go:"GO:0005876"(spindle microtubule)|go:"GO:0010880"(regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0021762"(substantia nigra development)|go:"GO:0030017"(sarcomere)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0032516"(positive regulation of phosphoprotein phosphatase activity)|go:"GO:0034704"(calcium channel complex)|go:"GO:0051343"(positive regulation of cyclic-nucleotide phosphodiesterase activity)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060316"(positive regulation of ryanodine-sensitive calcium-release channel activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072542"(protein phosphatase activator activity)|go:"GO:0014069"(postsynaptic density)|go:"GO:0099566"(regulation of postsynaptic cytosolic calcium ion concentration)|reactome:R-RNO-8876725|go:"GO:0001975"(response to amphetamine)|go:"GO:0051412"(response to corticosterone)|rcsb pdb:4EHQ|rcsb pdb:4J9Y|rcsb pdb:4J9Z|reactome:R-RNO-163615|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0031800"(type 3 metabotropic glutamate receptor binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0048306"(calcium-dependent protein binding)|rcsb pdb:2MGU|ensembl:ENSRNOT00000022603|ensembl:ENSRNOT00000064679|rcsb pdb:3WLC|rcsb pdb:3WLD|reactome:R-RNO-111932|reactome:R-RNO-111933|reactome:R-RNO-111957|reactome:R-RNO-114608|reactome:R-RNO-1474151|reactome:R-RNO-1855204|reactome:R-RNO-203615|reactome:R-RNO-2514859|reactome:R-RNO-2871809|reactome:R-RNO-4086398|reactome:R-RNO-442717|reactome:R-RNO-442729|reactome:R-RNO-442745|reactome:R-RNO-442982|reactome:R-RNO-445355|reactome:R-RNO-451308|reactome:R-RNO-5218920|reactome:R-RNO-5607763|reactome:R-RNO-5626467|reactome:R-RNO-5627123|reactome:R-RNO-5673001|reactome:R-RNO-70221|ensembl:ENSRNOG00000004060|ensembl:ENSRNOG00000016770|ensembl:ENSRNOP00000022603|ensembl:ENSRNOP00000063822|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0019855"(calcium channel inhibitor activity)|go:"GO:0060315"(negative regulation of ryanodine-sensitive calcium-release channel activity) refseq:NP_000710.5|refseq:NP_001123299.1|refseq:NP_001123301.1|refseq:NP_001123303.1|refseq:NP_001123304.1|refseq:NP_001123305.1|refseq:NP_001123306.1|refseq:NP_001123307.1|refseq:NP_001123314.1|refseq:NP_001123315.1|refseq:NP_001123308.1|refseq:NP_001123309.1|refseq:NP_001123310.1|refseq:NP_001123311.1|refseq:NP_001123312.1|refseq:NP_001123313.1|refseq:NP_001123316.1|refseq:NP_001123318.1|refseq:NP_001161095.1|refseq:NP_001161097.1|refseq:NP_001123302.2|refseq:NP_001161096.2|refseq:NP_955630.3|reactome:R-HSA-5576893|reactome:R-HSA-400042|reactome:R-HSA-419037|reactome:R-HSA-422356|go:"GO:0002520"(immune system development)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007507"(heart development)|go:"GO:0008331"(high voltage-gated calcium channel activity)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030018"(Z disc)|go:"GO:0030425"(dendrite)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035585"(calcium-mediated signaling using extracellular calcium source)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043204"(perikaryon)|go:"GO:0045762"(positive regulation of adenylate cyclase activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0051393"(alpha-actinin binding)|go:"GO:0060402"(calcium ion transport into cytosol)|go:"GO:0061337"(cardiac conduction)|go:"GO:0061577"(calcium ion transmembrane transport via high voltage-gated calcium channel)|go:"GO:0070509"(calcium ion import)|go:"GO:0086002"(cardiac muscle cell action potential involved in contraction)|go:"GO:0086007"(voltage-gated calcium channel activity involved in cardiac muscle cell action potential)|go:"GO:0086012"(membrane depolarization during cardiac muscle cell action potential)|go:"GO:0086045"(membrane depolarization during AV node cell action potential)|go:"GO:0086056"(voltage-gated calcium channel activity involved in AV node cell action potential)|go:"GO:0086064"(cell communication by electrical coupling involved in cardiac conduction)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|go:"GO:0098912"(membrane depolarization during atrial cardiac muscle cell action potential)|go:"GO:1990454"(L-type voltage-gated calcium channel complex)|interpro:IPR002077(Voltage-dependent calcium channel, alpha-1 subunit)|interpro:IPR005446(Voltage-dependent calcium channel, L-type, alpha-1 subunit)|interpro:IPR005451(Voltage-dependent calcium channel, L-type, alpha-1C subunit)|interpro:IPR005821(Ion transport)|interpro:IPR014873(Voltage-dependent calcium channel, alpha-1 subunit, IQ domain)|interpro:IPR027359|interpro:IPR031649|interpro:IPR031688|rcsb pdb:1T0J|rcsb pdb:2BE6|rcsb pdb:2F3Y|rcsb pdb:2F3Z|rcsb pdb:2LQC|rcsb pdb:3G43|rcsb pdb:3OXQ|rcsb pdb:5V2P|rcsb pdb:5V2Q|rcsb pdb:6C0A|rcsb pdb:6DAD|rcsb pdb:6DAE|rcsb pdb:6DAF|rcsb pdb:6U39|rcsb pdb:6U3A|rcsb pdb:6U3B|rcsb pdb:6U3D|go:"GO:0070588"(calcium ion transmembrane transport)|reactome:R-HSA-5576892|dip:DIP-29589N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9534(chlae)|taxid:9534(Chlorocebus aethiops) - 2017/08/05 2019/04/16 rogid:tTYcOd9bOh211njZVz7cYVybAMQ10116 rogid:dhWcWUTulWYd/nQtGorjr481/XA9606 rigid:D3NEoSVMDlEnRa5peTH5k+i8Zic false cyan fluorescent protein tag:0-0 flag tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q02641-1 uniprotkb:Q13936 intact:EBI-15707950|ensembl:ENSP00000377840 intact:EBI-1038838|uniprotkb:Q13917|uniprotkb:Q13918|uniprotkb:Q13919|uniprotkb:Q13920|uniprotkb:Q13921|uniprotkb:Q13922|uniprotkb:Q13923|uniprotkb:Q13924|uniprotkb:Q13925|uniprotkb:Q13926|uniprotkb:Q13927|uniprotkb:Q13928|uniprotkb:Q13929|uniprotkb:Q13930|uniprotkb:Q13932|uniprotkb:Q13933|uniprotkb:Q14743|uniprotkb:Q14744|uniprotkb:Q15877|uniprotkb:Q4VMI7|uniprotkb:Q4VMI8|uniprotkb:Q4VMI9|uniprotkb:Q6PKM7|uniprotkb:Q8N6C0|uniprotkb:Q99025|uniprotkb:Q99241|uniprotkb:Q99875|uniprotkb:B2RUT3|uniprotkb:E9PDJ0 psi-mi:q02641-1(display_long)|uniprotkb:CACNB1(gene name)|psi-mi:CACNB1(display_short)|uniprotkb:CACNLB1(gene name synonym)|uniprotkb:Calcium channel voltage-dependent subunit beta 1(gene name synonym)|uniprotkb:Beta-1B(isoform synonym)|uniprotkb:Beta-1b2(isoform synonym)|uniprotkb:Beta1-2(isoform synonym)|uniprotkb:BetaA(isoform synonym) psi-mi:cac1c_human(display_long)|uniprotkb:CACNA1C(gene name)|psi-mi:CACNA1C(display_short)|uniprotkb:CACH2(gene name synonym)|uniprotkb:CACN2(gene name synonym)|uniprotkb:CACNL1A1(gene name synonym)|uniprotkb:CCHL1A1(gene name synonym)|uniprotkb:Voltage-gated calcium channel subunit alpha Cav1.2(gene name synonym)|uniprotkb:Calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ravindran et al. (2008) pubmed:18535142|doi:10.1073/pnas.0711624105|imex:IM-9366 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15708055|imex:IM-9366-5|dip:DIP-87915E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-947514(isoform-parent)|ensembl:ENSG00000067191(gene)|ensembl:ENST00000394303(transcript) refseq:NP_000710.5|refseq:NP_001123299.1|refseq:NP_001123301.1|refseq:NP_001123303.1|refseq:NP_001123304.1|refseq:NP_001123305.1|refseq:NP_001123306.1|refseq:NP_001123307.1|refseq:NP_001123314.1|refseq:NP_001123315.1|refseq:NP_001123308.1|refseq:NP_001123309.1|refseq:NP_001123310.1|refseq:NP_001123311.1|refseq:NP_001123312.1|refseq:NP_001123313.1|refseq:NP_001123316.1|refseq:NP_001123318.1|refseq:NP_001161095.1|refseq:NP_001161097.1|refseq:NP_001123302.2|refseq:NP_001161096.2|refseq:NP_955630.3|reactome:R-HSA-5576893|reactome:R-HSA-400042|reactome:R-HSA-419037|reactome:R-HSA-422356|go:"GO:0002520"(immune system development)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007507"(heart development)|go:"GO:0008331"(high voltage-gated calcium channel activity)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030018"(Z disc)|go:"GO:0030425"(dendrite)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035585"(calcium-mediated signaling using extracellular calcium source)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043204"(perikaryon)|go:"GO:0045762"(positive regulation of adenylate cyclase activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0051393"(alpha-actinin binding)|go:"GO:0060402"(calcium ion transport into cytosol)|go:"GO:0061337"(cardiac conduction)|go:"GO:0061577"(calcium ion transmembrane transport via high voltage-gated calcium channel)|go:"GO:0070509"(calcium ion import)|go:"GO:0086002"(cardiac muscle cell action potential involved in contraction)|go:"GO:0086007"(voltage-gated calcium channel activity involved in cardiac muscle cell action potential)|go:"GO:0086012"(membrane depolarization during cardiac muscle cell action potential)|go:"GO:0086045"(membrane depolarization during AV node cell action potential)|go:"GO:0086056"(voltage-gated calcium channel activity involved in AV node cell action potential)|go:"GO:0086064"(cell communication by electrical coupling involved in cardiac conduction)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|go:"GO:0098912"(membrane depolarization during atrial cardiac muscle cell action potential)|go:"GO:1990454"(L-type voltage-gated calcium channel complex)|interpro:IPR002077(Voltage-dependent calcium channel, alpha-1 subunit)|interpro:IPR005446(Voltage-dependent calcium channel, L-type, alpha-1 subunit)|interpro:IPR005451(Voltage-dependent calcium channel, L-type, alpha-1C subunit)|interpro:IPR005821(Ion transport)|interpro:IPR014873(Voltage-dependent calcium channel, alpha-1 subunit, IQ domain)|interpro:IPR027359|interpro:IPR031649|interpro:IPR031688|rcsb pdb:1T0J|rcsb pdb:2BE6|rcsb pdb:2F3Y|rcsb pdb:2F3Z|rcsb pdb:2LQC|rcsb pdb:3G43|rcsb pdb:3OXQ|rcsb pdb:5V2P|rcsb pdb:5V2Q|rcsb pdb:6C0A|rcsb pdb:6DAD|rcsb pdb:6DAE|rcsb pdb:6DAF|rcsb pdb:6U39|rcsb pdb:6U3A|rcsb pdb:6U3B|rcsb pdb:6U3D|go:"GO:0070588"(calcium ion transmembrane transport)|reactome:R-HSA-5576892|dip:DIP-29589N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9534(chlae)|taxid:9534(Chlorocebus aethiops) - 2017/08/05 2019/04/16 rogid:nP0QYe6Gr+aIneTmyLWfPuvMEfk9606 rogid:dhWcWUTulWYd/nQtGorjr481/XA9606 rigid:3nGOm7lRHNs54UfFR/QRpmb8sEA false - flag tag:n-n - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q13936 uniprotkb:Q08289-1 intact:EBI-1038838|uniprotkb:Q13917|uniprotkb:Q13918|uniprotkb:Q13919|uniprotkb:Q13920|uniprotkb:Q13921|uniprotkb:Q13922|uniprotkb:Q13923|uniprotkb:Q13924|uniprotkb:Q13925|uniprotkb:Q13926|uniprotkb:Q13927|uniprotkb:Q13928|uniprotkb:Q13929|uniprotkb:Q13930|uniprotkb:Q13932|uniprotkb:Q13933|uniprotkb:Q14743|uniprotkb:Q14744|uniprotkb:Q15877|uniprotkb:Q4VMI7|uniprotkb:Q4VMI8|uniprotkb:Q4VMI9|uniprotkb:Q6PKM7|uniprotkb:Q8N6C0|uniprotkb:Q99025|uniprotkb:Q99241|uniprotkb:Q99875|uniprotkb:B2RUT3|uniprotkb:E9PDJ0 intact:EBI-15707999|ensembl:ENSP00000320025 psi-mi:cac1c_human(display_long)|uniprotkb:CACNA1C(gene name)|psi-mi:CACNA1C(display_short)|uniprotkb:CACH2(gene name synonym)|uniprotkb:CACN2(gene name synonym)|uniprotkb:CACNL1A1(gene name synonym)|uniprotkb:CCHL1A1(gene name synonym)|uniprotkb:Voltage-gated calcium channel subunit alpha Cav1.2(gene name synonym)|uniprotkb:Calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle(gene name synonym) psi-mi:q08289-1(display_long)|uniprotkb:CACNB2(gene name)|psi-mi:CACNB2(display_short)|uniprotkb:CACNLB2(gene name synonym)|uniprotkb:MYSB(gene name synonym)|uniprotkb:CACNB2d(isoform synonym)|uniprotkb:Calcium channel voltage-dependent subunit beta 2(gene name synonym)|uniprotkb:Lambert-Eaton myasthenic syndrome antigen B(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ravindran et al. (2008) pubmed:18535142|doi:10.1073/pnas.0711624105|imex:IM-9366 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15708032|imex:IM-9366-4|dip:DIP-87913E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000710.5|refseq:NP_001123299.1|refseq:NP_001123301.1|refseq:NP_001123303.1|refseq:NP_001123304.1|refseq:NP_001123305.1|refseq:NP_001123306.1|refseq:NP_001123307.1|refseq:NP_001123314.1|refseq:NP_001123315.1|refseq:NP_001123308.1|refseq:NP_001123309.1|refseq:NP_001123310.1|refseq:NP_001123311.1|refseq:NP_001123312.1|refseq:NP_001123313.1|refseq:NP_001123316.1|refseq:NP_001123318.1|refseq:NP_001161095.1|refseq:NP_001161097.1|refseq:NP_001123302.2|refseq:NP_001161096.2|refseq:NP_955630.3|reactome:R-HSA-5576893|reactome:R-HSA-400042|reactome:R-HSA-419037|reactome:R-HSA-422356|go:"GO:0002520"(immune system development)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007507"(heart development)|go:"GO:0008331"(high voltage-gated calcium channel activity)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030018"(Z disc)|go:"GO:0030425"(dendrite)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035585"(calcium-mediated signaling using extracellular calcium source)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043204"(perikaryon)|go:"GO:0045762"(positive regulation of adenylate cyclase activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0051393"(alpha-actinin binding)|go:"GO:0060402"(calcium ion transport into cytosol)|go:"GO:0061337"(cardiac conduction)|go:"GO:0061577"(calcium ion transmembrane transport via high voltage-gated calcium channel)|go:"GO:0070509"(calcium ion import)|go:"GO:0086002"(cardiac muscle cell action potential involved in contraction)|go:"GO:0086007"(voltage-gated calcium channel activity involved in cardiac muscle cell action potential)|go:"GO:0086012"(membrane depolarization during cardiac muscle cell action potential)|go:"GO:0086045"(membrane depolarization during AV node cell action potential)|go:"GO:0086056"(voltage-gated calcium channel activity involved in AV node cell action potential)|go:"GO:0086064"(cell communication by electrical coupling involved in cardiac conduction)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|go:"GO:0098912"(membrane depolarization during atrial cardiac muscle cell action potential)|go:"GO:1990454"(L-type voltage-gated calcium channel complex)|interpro:IPR002077(Voltage-dependent calcium channel, alpha-1 subunit)|interpro:IPR005446(Voltage-dependent calcium channel, L-type, alpha-1 subunit)|interpro:IPR005451(Voltage-dependent calcium channel, L-type, alpha-1C subunit)|interpro:IPR005821(Ion transport)|interpro:IPR014873(Voltage-dependent calcium channel, alpha-1 subunit, IQ domain)|interpro:IPR027359|interpro:IPR031649|interpro:IPR031688|rcsb pdb:1T0J|rcsb pdb:2BE6|rcsb pdb:2F3Y|rcsb pdb:2F3Z|rcsb pdb:2LQC|rcsb pdb:3G43|rcsb pdb:3OXQ|rcsb pdb:5V2P|rcsb pdb:5V2Q|rcsb pdb:6C0A|rcsb pdb:6DAD|rcsb pdb:6DAE|rcsb pdb:6DAF|rcsb pdb:6U39|rcsb pdb:6U3A|rcsb pdb:6U3B|rcsb pdb:6U3D|go:"GO:0070588"(calcium ion transmembrane transport)|reactome:R-HSA-5576892|dip:DIP-29589N ensembl:ENSG00000165995(gene)|ensembl:ENST00000324631(transcript)|intact:EBI-2874501(isoform-parent) psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9534(chlae)|taxid:9534(Chlorocebus aethiops) - 2017/08/05 2019/04/16 rogid:dhWcWUTulWYd/nQtGorjr481/XA9606 rogid:62aD9Wbg0RTCIwNCGexJvVgKkGE9606 rigid:r6cIsUDzOA8pL9P1O1RVo3ATZzM false flag tag:n-n fluorescent protein tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q13936 uniprotkb:Q08289-1 intact:EBI-1038838|uniprotkb:Q13917|uniprotkb:Q13918|uniprotkb:Q13919|uniprotkb:Q13920|uniprotkb:Q13921|uniprotkb:Q13922|uniprotkb:Q13923|uniprotkb:Q13924|uniprotkb:Q13925|uniprotkb:Q13926|uniprotkb:Q13927|uniprotkb:Q13928|uniprotkb:Q13929|uniprotkb:Q13930|uniprotkb:Q13932|uniprotkb:Q13933|uniprotkb:Q14743|uniprotkb:Q14744|uniprotkb:Q15877|uniprotkb:Q4VMI7|uniprotkb:Q4VMI8|uniprotkb:Q4VMI9|uniprotkb:Q6PKM7|uniprotkb:Q8N6C0|uniprotkb:Q99025|uniprotkb:Q99241|uniprotkb:Q99875|uniprotkb:B2RUT3|uniprotkb:E9PDJ0 intact:EBI-15707999|ensembl:ENSP00000320025 psi-mi:cac1c_human(display_long)|uniprotkb:CACNA1C(gene name)|psi-mi:CACNA1C(display_short)|uniprotkb:CACH2(gene name synonym)|uniprotkb:CACN2(gene name synonym)|uniprotkb:CACNL1A1(gene name synonym)|uniprotkb:CCHL1A1(gene name synonym)|uniprotkb:Voltage-gated calcium channel subunit alpha Cav1.2(gene name synonym)|uniprotkb:Calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle(gene name synonym) psi-mi:q08289-1(display_long)|uniprotkb:CACNB2(gene name)|psi-mi:CACNB2(display_short)|uniprotkb:CACNLB2(gene name synonym)|uniprotkb:MYSB(gene name synonym)|uniprotkb:CACNB2d(isoform synonym)|uniprotkb:Calcium channel voltage-dependent subunit beta 2(gene name synonym)|uniprotkb:Lambert-Eaton myasthenic syndrome antigen B(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ravindran et al. (2008) pubmed:18535142|doi:10.1073/pnas.0711624105|imex:IM-9366 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15708156|imex:IM-9366-10|dip:DIP-87913E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000710.5|refseq:NP_001123299.1|refseq:NP_001123301.1|refseq:NP_001123303.1|refseq:NP_001123304.1|refseq:NP_001123305.1|refseq:NP_001123306.1|refseq:NP_001123307.1|refseq:NP_001123314.1|refseq:NP_001123315.1|refseq:NP_001123308.1|refseq:NP_001123309.1|refseq:NP_001123310.1|refseq:NP_001123311.1|refseq:NP_001123312.1|refseq:NP_001123313.1|refseq:NP_001123316.1|refseq:NP_001123318.1|refseq:NP_001161095.1|refseq:NP_001161097.1|refseq:NP_001123302.2|refseq:NP_001161096.2|refseq:NP_955630.3|reactome:R-HSA-5576893|reactome:R-HSA-400042|reactome:R-HSA-419037|reactome:R-HSA-422356|go:"GO:0002520"(immune system development)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007507"(heart development)|go:"GO:0008331"(high voltage-gated calcium channel activity)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030018"(Z disc)|go:"GO:0030425"(dendrite)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035585"(calcium-mediated signaling using extracellular calcium source)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043204"(perikaryon)|go:"GO:0045762"(positive regulation of adenylate cyclase activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0051393"(alpha-actinin binding)|go:"GO:0060402"(calcium ion transport into cytosol)|go:"GO:0061337"(cardiac conduction)|go:"GO:0061577"(calcium ion transmembrane transport via high voltage-gated calcium channel)|go:"GO:0070509"(calcium ion import)|go:"GO:0086002"(cardiac muscle cell action potential involved in contraction)|go:"GO:0086007"(voltage-gated calcium channel activity involved in cardiac muscle cell action potential)|go:"GO:0086012"(membrane depolarization during cardiac muscle cell action potential)|go:"GO:0086045"(membrane depolarization during AV node cell action potential)|go:"GO:0086056"(voltage-gated calcium channel activity involved in AV node cell action potential)|go:"GO:0086064"(cell communication by electrical coupling involved in cardiac conduction)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|go:"GO:0098912"(membrane depolarization during atrial cardiac muscle cell action potential)|go:"GO:1990454"(L-type voltage-gated calcium channel complex)|interpro:IPR002077(Voltage-dependent calcium channel, alpha-1 subunit)|interpro:IPR005446(Voltage-dependent calcium channel, L-type, alpha-1 subunit)|interpro:IPR005451(Voltage-dependent calcium channel, L-type, alpha-1C subunit)|interpro:IPR005821(Ion transport)|interpro:IPR014873(Voltage-dependent calcium channel, alpha-1 subunit, IQ domain)|interpro:IPR027359|interpro:IPR031649|interpro:IPR031688|rcsb pdb:1T0J|rcsb pdb:2BE6|rcsb pdb:2F3Y|rcsb pdb:2F3Z|rcsb pdb:2LQC|rcsb pdb:3G43|rcsb pdb:3OXQ|rcsb pdb:5V2P|rcsb pdb:5V2Q|rcsb pdb:6C0A|rcsb pdb:6DAD|rcsb pdb:6DAE|rcsb pdb:6DAF|rcsb pdb:6U39|rcsb pdb:6U3A|rcsb pdb:6U3B|rcsb pdb:6U3D|go:"GO:0070588"(calcium ion transmembrane transport)|reactome:R-HSA-5576892|dip:DIP-29589N ensembl:ENSG00000165995(gene)|ensembl:ENST00000324631(transcript)|intact:EBI-2874501(isoform-parent) psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9534(chlae)|taxid:9534(Chlorocebus aethiops) - 2017/08/05 2019/04/16 rogid:dhWcWUTulWYd/nQtGorjr481/XA9606 rogid:62aD9Wbg0RTCIwNCGexJvVgKkGE9606 rigid:r6cIsUDzOA8pL9P1O1RVo3ATZzM false flag tag:n-n - - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot)