#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q01083 uniprotkb:Q00805 intact:EBI-91342|ensemblmetazoa:FBpp0080808|ensemblmetazoa:FBpp0080809|ensemblmetazoa:FBpp0080810|ensemblmetazoa:FBpp0080811|ensemblmetazoa:FBpp0100054|uniprotkb:Q8SXE0|uniprotkb:Q9VIT4 intact:EBI-596393|uniprotkb:Q8MQZ2|uniprotkb:Q9VV64|ensemblmetazoa:FBpp0075166 psi-mi:spitz_drome(display_long)|uniprotkb:spi(gene name)|psi-mi:spi(display_short)|uniprotkb:CG10334(orf name) psi-mi:gil_drome(display_long)|uniprotkb:Protein argos(gene name synonym)|uniprotkb:Protein strawberry(gene name synonym)|uniprotkb:aos(gene name)|psi-mi:aos(display_short)|uniprotkb:gil(gene name synonym)|uniprotkb:sty(gene name synonym)|uniprotkb:CG4531(orf name) psi-mi:"MI:0114"(x-ray crystallography) Klein et al. (2008) pubmed:18500331|doi:10.1038/nature06978|imex:IM-21993 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15704334|imex:IM-21993-2|dip:DIP-195727E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005789"(endoplasmic reticulum membrane)|ensemblmetazoa:FBgn0005672(gene)|ensemblmetazoa:FBtr0081267(transcript)|ensemblmetazoa:FBtr0081268(transcript)|ensemblmetazoa:FBtr0081269(transcript)|ensemblmetazoa:FBtr0081270(transcript)|ensemblmetazoa:FBtr0100597(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001713"(ectodermal cell fate determination)|go:"GO:0003015"(heart process)|go:"GO:0005154"(epidermal growth factor receptor binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005783"(endoplasmic reticulum)|refseq:NP_001027281.1|refseq:NP_476909.2|refseq:NP_599118.2|refseq:NP_599119.2|refseq:NP_599120.2|flybase:FBgn0005672|go:"GO:0005886"(plasma membrane)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007298"(border follicle cell migration)|go:"GO:0007391"(dorsal closure)|go:"GO:0007421"(stomatogastric nervous system development)|go:"GO:0007422"(peripheral nervous system development)|go:"GO:0007438"(oenocyte development)|go:"GO:0007476"(imaginal disc-derived wing morphogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008355"(olfactory learning)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016318"(ommatidial rotation)|go:"GO:0035225"(determination of genital disc primordium)|go:"GO:0035277"(spiracle morphogenesis, open tracheal system)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043703"(photoreceptor cell fate determination)|go:"GO:0046530"(photoreceptor cell differentiation)|go:"GO:0048018"(receptor ligand activity)|go:"GO:0048149"(behavioral response to ethanol)|go:"GO:0048865"(stem cell fate commitment)|go:"GO:0050769"(positive regulation of neurogenesis)|go:"GO:0061331"(epithelial cell proliferation involved in Malpighian tubule morphogenesis)|go:"GO:1903688"(positive regulation of border follicle cell migration)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR043403|rcsb pdb:3C9A|rcsb pdb:3CA7|rcsb pdb:3LTF|rcsb pdb:3LTG|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|dip:DIP-18037N refseq:NP_524107.2|flybase:FBgn0004569|dip:DIP-60630N|ensemblmetazoa:FBgn0004569(gene)|ensemblmetazoa:FBtr0075408(transcript)|go:"GO:0001654"(eye development)|go:"GO:0005154"(epidermal growth factor receptor binding)|go:"GO:0005615"(extracellular space)|go:"GO:0007175"(negative regulation of epidermal growth factor-activated receptor activity)|go:"GO:0007455"(eye-antennal disc morphogenesis)|go:"GO:0007472"(wing disc morphogenesis)|go:"GO:0007474"(imaginal disc-derived wing vein specification)|go:"GO:0007476"(imaginal disc-derived wing morphogenesis)|go:"GO:0007482"(haltere development)|go:"GO:0007601"(visual perception)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0016318"(ommatidial rotation)|go:"GO:0035215"(genital disc development)|go:"GO:0042059"(negative regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0050768"(negative regulation of neurogenesis)|go:"GO:0050896"(response to stimulus)|go:"GO:0060233"(oenocyte delamination)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:2000737"(negative regulation of stem cell differentiation)|interpro:IPR021633|rcsb pdb:3C9A|rcsb pdb:3CGU psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/05 2017/08/10 rogid:RO8D5JspHbtNUFx11JHFCoUuv0A7227 rogid:aydIK44+0WVEAC0I/benId7LOnQ7227 rigid:blrliDhznfBEHhQRsWGkFfvnC0M false sufficient binding region:76-127 sufficient binding region:285-444,113-164 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q00805 uniprotkb:Q00805 intact:EBI-596393|uniprotkb:Q8MQZ2|uniprotkb:Q9VV64|ensemblmetazoa:FBpp0075166 intact:EBI-596393|uniprotkb:Q8MQZ2|uniprotkb:Q9VV64|ensemblmetazoa:FBpp0075166 psi-mi:gil_drome(display_long)|uniprotkb:Protein argos(gene name synonym)|uniprotkb:Protein strawberry(gene name synonym)|uniprotkb:aos(gene name)|psi-mi:aos(display_short)|uniprotkb:gil(gene name synonym)|uniprotkb:sty(gene name synonym)|uniprotkb:CG4531(orf name) psi-mi:gil_drome(display_long)|uniprotkb:Protein argos(gene name synonym)|uniprotkb:Protein strawberry(gene name synonym)|uniprotkb:aos(gene name)|psi-mi:aos(display_short)|uniprotkb:gil(gene name synonym)|uniprotkb:sty(gene name synonym)|uniprotkb:CG4531(orf name) psi-mi:"MI:0071"(molecular sieving) Klein et al. (2008) pubmed:18500331|doi:10.1038/nature06978|imex:IM-21993 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15704314|imex:IM-21993-1|dip:DIP-195726E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_524107.2|flybase:FBgn0004569|dip:DIP-60630N|ensemblmetazoa:FBgn0004569(gene)|ensemblmetazoa:FBtr0075408(transcript)|go:"GO:0001654"(eye development)|go:"GO:0005154"(epidermal growth factor receptor binding)|go:"GO:0005615"(extracellular space)|go:"GO:0007175"(negative regulation of epidermal growth factor-activated receptor activity)|go:"GO:0007455"(eye-antennal disc morphogenesis)|go:"GO:0007472"(wing disc morphogenesis)|go:"GO:0007474"(imaginal disc-derived wing vein specification)|go:"GO:0007476"(imaginal disc-derived wing morphogenesis)|go:"GO:0007482"(haltere development)|go:"GO:0007601"(visual perception)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0016318"(ommatidial rotation)|go:"GO:0035215"(genital disc development)|go:"GO:0042059"(negative regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0050768"(negative regulation of neurogenesis)|go:"GO:0050896"(response to stimulus)|go:"GO:0060233"(oenocyte delamination)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:2000737"(negative regulation of stem cell differentiation)|interpro:IPR021633|rcsb pdb:3C9A|rcsb pdb:3CGU refseq:NP_524107.2|flybase:FBgn0004569|dip:DIP-60630N|ensemblmetazoa:FBgn0004569(gene)|ensemblmetazoa:FBtr0075408(transcript)|go:"GO:0001654"(eye development)|go:"GO:0005154"(epidermal growth factor receptor binding)|go:"GO:0005615"(extracellular space)|go:"GO:0007175"(negative regulation of epidermal growth factor-activated receptor activity)|go:"GO:0007455"(eye-antennal disc morphogenesis)|go:"GO:0007472"(wing disc morphogenesis)|go:"GO:0007474"(imaginal disc-derived wing vein specification)|go:"GO:0007476"(imaginal disc-derived wing morphogenesis)|go:"GO:0007482"(haltere development)|go:"GO:0007601"(visual perception)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0016318"(ommatidial rotation)|go:"GO:0035215"(genital disc development)|go:"GO:0042059"(negative regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0050768"(negative regulation of neurogenesis)|go:"GO:0050896"(response to stimulus)|go:"GO:0060233"(oenocyte delamination)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:2000737"(negative regulation of stem cell differentiation)|interpro:IPR021633|rcsb pdb:3C9A|rcsb pdb:3CGU psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7108(spofr)|taxid:7108("Spodoptera frugiperda (Fall armyworm)") - 2017/08/05 2017/08/10 rogid:aydIK44+0WVEAC0I/benId7LOnQ7227 rogid:aydIK44+0WVEAC0I/benId7LOnQ7227 rigid:zy0/DqjtrEPcb8kYgdMXl/OXZic false sufficient binding region:285-444,113-164 sufficient binding region:285-444,113-164 - 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q01083 uniprotkb:Q00805 intact:EBI-91342|ensemblmetazoa:FBpp0080808|ensemblmetazoa:FBpp0080809|ensemblmetazoa:FBpp0080810|ensemblmetazoa:FBpp0080811|ensemblmetazoa:FBpp0100054|uniprotkb:Q8SXE0|uniprotkb:Q9VIT4 intact:EBI-596393|uniprotkb:Q8MQZ2|uniprotkb:Q9VV64|ensemblmetazoa:FBpp0075166 psi-mi:spitz_drome(display_long)|uniprotkb:spi(gene name)|psi-mi:spi(display_short)|uniprotkb:CG10334(orf name) psi-mi:gil_drome(display_long)|uniprotkb:Protein argos(gene name synonym)|uniprotkb:Protein strawberry(gene name synonym)|uniprotkb:aos(gene name)|psi-mi:aos(display_short)|uniprotkb:gil(gene name synonym)|uniprotkb:sty(gene name synonym)|uniprotkb:CG4531(orf name) psi-mi:"MI:0107"(surface plasmon resonance) Klein et al. (2008) pubmed:18500331|doi:10.1038/nature06978|imex:IM-21993 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15704375|imex:IM-21993-4|dip:DIP-195727E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005789"(endoplasmic reticulum membrane)|ensemblmetazoa:FBgn0005672(gene)|ensemblmetazoa:FBtr0081267(transcript)|ensemblmetazoa:FBtr0081268(transcript)|ensemblmetazoa:FBtr0081269(transcript)|ensemblmetazoa:FBtr0081270(transcript)|ensemblmetazoa:FBtr0100597(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001713"(ectodermal cell fate determination)|go:"GO:0003015"(heart process)|go:"GO:0005154"(epidermal growth factor receptor binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005783"(endoplasmic reticulum)|refseq:NP_001027281.1|refseq:NP_476909.2|refseq:NP_599118.2|refseq:NP_599119.2|refseq:NP_599120.2|flybase:FBgn0005672|go:"GO:0005886"(plasma membrane)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007298"(border follicle cell migration)|go:"GO:0007391"(dorsal closure)|go:"GO:0007421"(stomatogastric nervous system development)|go:"GO:0007422"(peripheral nervous system development)|go:"GO:0007438"(oenocyte development)|go:"GO:0007476"(imaginal disc-derived wing morphogenesis)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008355"(olfactory learning)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016318"(ommatidial rotation)|go:"GO:0035225"(determination of genital disc primordium)|go:"GO:0035277"(spiracle morphogenesis, open tracheal system)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043703"(photoreceptor cell fate determination)|go:"GO:0046530"(photoreceptor cell differentiation)|go:"GO:0048018"(receptor ligand activity)|go:"GO:0048149"(behavioral response to ethanol)|go:"GO:0048865"(stem cell fate commitment)|go:"GO:0050769"(positive regulation of neurogenesis)|go:"GO:0061331"(epithelial cell proliferation involved in Malpighian tubule morphogenesis)|go:"GO:1903688"(positive regulation of border follicle cell migration)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR043403|rcsb pdb:3C9A|rcsb pdb:3CA7|rcsb pdb:3LTF|rcsb pdb:3LTG|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|dip:DIP-18037N refseq:NP_524107.2|flybase:FBgn0004569|dip:DIP-60630N|ensemblmetazoa:FBgn0004569(gene)|ensemblmetazoa:FBtr0075408(transcript)|go:"GO:0001654"(eye development)|go:"GO:0005154"(epidermal growth factor receptor binding)|go:"GO:0005615"(extracellular space)|go:"GO:0007175"(negative regulation of epidermal growth factor-activated receptor activity)|go:"GO:0007455"(eye-antennal disc morphogenesis)|go:"GO:0007472"(wing disc morphogenesis)|go:"GO:0007474"(imaginal disc-derived wing vein specification)|go:"GO:0007476"(imaginal disc-derived wing morphogenesis)|go:"GO:0007482"(haltere development)|go:"GO:0007601"(visual perception)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0016318"(ommatidial rotation)|go:"GO:0035215"(genital disc development)|go:"GO:0042059"(negative regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0050768"(negative regulation of neurogenesis)|go:"GO:0050896"(response to stimulus)|go:"GO:0060233"(oenocyte delamination)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:2000737"(negative regulation of stem cell differentiation)|interpro:IPR021633|rcsb pdb:3C9A|rcsb pdb:3CGU psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/05 2017/08/10 rogid:RO8D5JspHbtNUFx11JHFCoUuv0A7227 rogid:aydIK44+0WVEAC0I/benId7LOnQ7227 rigid:blrliDhznfBEHhQRsWGkFfvnC0M false sufficient binding region:76-127 sufficient binding region:285-444,113-164 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q00805 uniprotkb:Q00805 intact:EBI-596393|uniprotkb:Q8MQZ2|uniprotkb:Q9VV64|ensemblmetazoa:FBpp0075166 intact:EBI-596393|uniprotkb:Q8MQZ2|uniprotkb:Q9VV64|ensemblmetazoa:FBpp0075166 psi-mi:gil_drome(display_long)|uniprotkb:Protein argos(gene name synonym)|uniprotkb:Protein strawberry(gene name synonym)|uniprotkb:aos(gene name)|psi-mi:aos(display_short)|uniprotkb:gil(gene name synonym)|uniprotkb:sty(gene name synonym)|uniprotkb:CG4531(orf name) psi-mi:gil_drome(display_long)|uniprotkb:Protein argos(gene name synonym)|uniprotkb:Protein strawberry(gene name synonym)|uniprotkb:aos(gene name)|psi-mi:aos(display_short)|uniprotkb:gil(gene name synonym)|uniprotkb:sty(gene name synonym)|uniprotkb:CG4531(orf name) psi-mi:"MI:0028"(cosedimentation in solution) Klein et al. (2008) pubmed:18500331|doi:10.1038/nature06978|imex:IM-21993 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15704356|imex:IM-21993-3|dip:DIP-195726E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_524107.2|flybase:FBgn0004569|dip:DIP-60630N|ensemblmetazoa:FBgn0004569(gene)|ensemblmetazoa:FBtr0075408(transcript)|go:"GO:0001654"(eye development)|go:"GO:0005154"(epidermal growth factor receptor binding)|go:"GO:0005615"(extracellular space)|go:"GO:0007175"(negative regulation of epidermal growth factor-activated receptor activity)|go:"GO:0007455"(eye-antennal disc morphogenesis)|go:"GO:0007472"(wing disc morphogenesis)|go:"GO:0007474"(imaginal disc-derived wing vein specification)|go:"GO:0007476"(imaginal disc-derived wing morphogenesis)|go:"GO:0007482"(haltere development)|go:"GO:0007601"(visual perception)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0016318"(ommatidial rotation)|go:"GO:0035215"(genital disc development)|go:"GO:0042059"(negative regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0050768"(negative regulation of neurogenesis)|go:"GO:0050896"(response to stimulus)|go:"GO:0060233"(oenocyte delamination)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:2000737"(negative regulation of stem cell differentiation)|interpro:IPR021633|rcsb pdb:3C9A|rcsb pdb:3CGU refseq:NP_524107.2|flybase:FBgn0004569|dip:DIP-60630N|ensemblmetazoa:FBgn0004569(gene)|ensemblmetazoa:FBtr0075408(transcript)|go:"GO:0001654"(eye development)|go:"GO:0005154"(epidermal growth factor receptor binding)|go:"GO:0005615"(extracellular space)|go:"GO:0007175"(negative regulation of epidermal growth factor-activated receptor activity)|go:"GO:0007455"(eye-antennal disc morphogenesis)|go:"GO:0007472"(wing disc morphogenesis)|go:"GO:0007474"(imaginal disc-derived wing vein specification)|go:"GO:0007476"(imaginal disc-derived wing morphogenesis)|go:"GO:0007482"(haltere development)|go:"GO:0007601"(visual perception)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0016318"(ommatidial rotation)|go:"GO:0035215"(genital disc development)|go:"GO:0042059"(negative regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0050768"(negative regulation of neurogenesis)|go:"GO:0050896"(response to stimulus)|go:"GO:0060233"(oenocyte delamination)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:2000737"(negative regulation of stem cell differentiation)|interpro:IPR021633|rcsb pdb:3C9A|rcsb pdb:3CGU psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7108(spofr)|taxid:7108("Spodoptera frugiperda (Fall armyworm)") - 2017/08/05 2017/08/10 rogid:aydIK44+0WVEAC0I/benId7LOnQ7227 rogid:aydIK44+0WVEAC0I/benId7LOnQ7227 rigid:zy0/DqjtrEPcb8kYgdMXl/OXZic false sufficient binding region:285-444,113-164 sufficient binding region:285-444,113-164 - 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q00805 uniprotkb:Q00805 intact:EBI-596393|uniprotkb:Q8MQZ2|uniprotkb:Q9VV64|ensemblmetazoa:FBpp0075166 intact:EBI-596393|uniprotkb:Q8MQZ2|uniprotkb:Q9VV64|ensemblmetazoa:FBpp0075166 psi-mi:gil_drome(display_long)|uniprotkb:Protein argos(gene name synonym)|uniprotkb:Protein strawberry(gene name synonym)|uniprotkb:aos(gene name)|psi-mi:aos(display_short)|uniprotkb:gil(gene name synonym)|uniprotkb:sty(gene name synonym)|uniprotkb:CG4531(orf name) psi-mi:gil_drome(display_long)|uniprotkb:Protein argos(gene name synonym)|uniprotkb:Protein strawberry(gene name synonym)|uniprotkb:aos(gene name)|psi-mi:aos(display_short)|uniprotkb:gil(gene name synonym)|uniprotkb:sty(gene name synonym)|uniprotkb:CG4531(orf name) psi-mi:"MI:0114"(x-ray crystallography) Klein et al. (2008) pubmed:18500331|doi:10.1038/nature06978|imex:IM-21993 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15704398|imex:IM-21993-5|dip:DIP-195726E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_524107.2|flybase:FBgn0004569|dip:DIP-60630N|ensemblmetazoa:FBgn0004569(gene)|ensemblmetazoa:FBtr0075408(transcript)|go:"GO:0001654"(eye development)|go:"GO:0005154"(epidermal growth factor receptor binding)|go:"GO:0005615"(extracellular space)|go:"GO:0007175"(negative regulation of epidermal growth factor-activated receptor activity)|go:"GO:0007455"(eye-antennal disc morphogenesis)|go:"GO:0007472"(wing disc morphogenesis)|go:"GO:0007474"(imaginal disc-derived wing vein specification)|go:"GO:0007476"(imaginal disc-derived wing morphogenesis)|go:"GO:0007482"(haltere development)|go:"GO:0007601"(visual perception)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0016318"(ommatidial rotation)|go:"GO:0035215"(genital disc development)|go:"GO:0042059"(negative regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0050768"(negative regulation of neurogenesis)|go:"GO:0050896"(response to stimulus)|go:"GO:0060233"(oenocyte delamination)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:2000737"(negative regulation of stem cell differentiation)|interpro:IPR021633|rcsb pdb:3C9A|rcsb pdb:3CGU refseq:NP_524107.2|flybase:FBgn0004569|dip:DIP-60630N|ensemblmetazoa:FBgn0004569(gene)|ensemblmetazoa:FBtr0075408(transcript)|go:"GO:0001654"(eye development)|go:"GO:0005154"(epidermal growth factor receptor binding)|go:"GO:0005615"(extracellular space)|go:"GO:0007175"(negative regulation of epidermal growth factor-activated receptor activity)|go:"GO:0007455"(eye-antennal disc morphogenesis)|go:"GO:0007472"(wing disc morphogenesis)|go:"GO:0007474"(imaginal disc-derived wing vein specification)|go:"GO:0007476"(imaginal disc-derived wing morphogenesis)|go:"GO:0007482"(haltere development)|go:"GO:0007601"(visual perception)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0016318"(ommatidial rotation)|go:"GO:0035215"(genital disc development)|go:"GO:0042059"(negative regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0050768"(negative regulation of neurogenesis)|go:"GO:0050896"(response to stimulus)|go:"GO:0060233"(oenocyte delamination)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:2000737"(negative regulation of stem cell differentiation)|interpro:IPR021633|rcsb pdb:3C9A|rcsb pdb:3CGU psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7108(spofr)|taxid:7108("Spodoptera frugiperda (Fall armyworm)") - 2017/08/05 2017/08/10 rogid:aydIK44+0WVEAC0I/benId7LOnQ7227 rogid:aydIK44+0WVEAC0I/benId7LOnQ7227 rigid:zy0/DqjtrEPcb8kYgdMXl/OXZic false sufficient binding region:285-444,113-164 sufficient binding region:285-444,113-164 - 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)