#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q16186 intact:EBI-4399559 intact:EBI-954387|ensembl:ENSP00000253003|ensembl:ENSP00000478877|uniprotkb:A0PKB1|uniprotkb:Q96FJ7|uniprotkb:Q9H1P2 dip:DIP-24261N psi-mi:adrm1_human(display_long)|uniprotkb:Adhesion-regulating molecule 1(gene name synonym)|uniprotkb:110 kDa cell membrane glycoprotein(gene name synonym)|uniprotkb:Rpn13 homolog(gene name synonym)|uniprotkb:Proteasome regulatory particle non-ATPase 13(gene name synonym)|uniprotkb:ADRM1(gene name)|psi-mi:ADRM1(display_short)|uniprotkb:GP110(gene name synonym) psi-mi:ubiq_human(display_short)|psi-mi:EBI-4399559(display_long) psi-mi:"MI:0077"(nuclear magnetic resonance) Schreiner et al. (2008) pubmed:18497827|doi:10.1038/nature06924|imex:IM-21990 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15704160|imex:IM-21990-1|dip:DIP-195716E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000130706(gene)|ensembl:ENST00000253003(transcript)|ensembl:ENST00000491935(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0002020"(protease binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008541"(proteasome regulatory particle, lid subcomplex)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043248"(proteasome assembly)|go:"GO:0061133"(endopeptidase activator activity)|go:"GO:0070628"(proteasome binding)|interpro:IPR006773(Adhesion regulating molecule)|interpro:IPR032368|interpro:IPR038108|interpro:IPR038633|interpro:IPR044867|interpro:IPR044868|mint:Q16186|rcsb pdb:2KQZ|rcsb pdb:2KR0|rcsb pdb:2L5V|rcsb pdb:2MKZ|rcsb pdb:2NBV|rcsb pdb:4UEL|rcsb pdb:4UEM|rcsb pdb:4WLQ|rcsb pdb:4WLR|rcsb pdb:5IRS|rcsb pdb:5V1Y|rcsb pdb:5V1Z|rcsb pdb:5YMY|rcsb pdb:6CO4|rcsb pdb:6OI4|rcsb pdb:6UYJ|reactome:R-HSA-5689603|reactome:R-HSA-5689880|rcsb pdb:6UYI|refseq:NP_008933.2|refseq:NP_783163.1|refseq:NP_001268366.1|refseq:NP_001268367.1|refseq:XP_005260314.1|dip:DIP-42668N uniprotkb:UBIQ_HUMAN(see-also)|refseq:NP_066289.2 psi-mi:"MI:0465"(dip) - no-uniprot-update: full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/05 2017/08/15 rogid:XrSLNnNr5Ojm0HkgcnnPube5Lno9606 rogid:dobaeYpohKyDSnm4fBbcy0ZbYwM9606 rigid:hWhOkarHoBGhAkwYF0Do5TDUSQY false sufficient binding region:1-150 - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9JKV1 intact:EBI-4399559 intact:EBI-8762776|uniprotkb:Q3UKZ8|uniprotkb:Q8BPH8|uniprotkb:Q922A7|ensembl:ENSMUSP00000050076 dip:DIP-24261N psi-mi:adrm1_mouse(display_long)|uniprotkb:Adrm1(gene name)|psi-mi:Adrm1(display_short)|uniprotkb:Gp110(gene name synonym)|uniprotkb:110 kDa cell membrane glycoprotein(gene name synonym)|uniprotkb:Adhesion-regulating molecule 1(gene name synonym)|uniprotkb:Rpn13 homolog(gene name synonym) psi-mi:ubiq_human(display_short)|psi-mi:EBI-4399559(display_long) psi-mi:"MI:0077"(nuclear magnetic resonance) Schreiner et al. (2008) pubmed:18497827|doi:10.1038/nature06924|imex:IM-21990 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15704180|imex:IM-21990-2|dip:DIP-195717E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062796.2|rcsb pdb:2R2Y|rcsb pdb:2Z59|reactome:R-MMU-5689603|reactome:R-MMU-5689880|ensembl:ENSMUSG00000039041(gene)|ensembl:ENSMUST00000061437(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0001541"(ovarian follicle development)|go:"GO:0002020"(protease binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007286"(spermatid development)|go:"GO:0008541"(proteasome regulatory particle, lid subcomplex)|go:"GO:0033081"(regulation of T cell differentiation in thymus)|go:"GO:0042699"(follicle-stimulating hormone signaling pathway)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043248"(proteasome assembly)|go:"GO:0048477"(oogenesis)|go:"GO:0048538"(thymus development)|go:"GO:0060009"(Sertoli cell development)|go:"GO:0060399"(positive regulation of growth hormone receptor signaling pathway)|go:"GO:0060612"(adipose tissue development)|go:"GO:0061133"(endopeptidase activator activity)|go:"GO:0070628"(proteasome binding)|go:"GO:0072520"(seminiferous tubule development)|interpro:IPR006773(Adhesion regulating molecule)|interpro:IPR032368|interpro:IPR038108|interpro:IPR038633|interpro:IPR044867|interpro:IPR044868|dip:DIP-60625N uniprotkb:UBIQ_HUMAN(see-also)|refseq:NP_066289.2 psi-mi:"MI:0465"(dip) - no-uniprot-update: full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/05 2017/08/15 rogid:Pq49mSSQ2aSkNE/UB63ORYtBOIc10090 rogid:dobaeYpohKyDSnm4fBbcy0ZbYwM9606 rigid:hB2Gt4DukTSzLm6lzYTNes9oAUQ false sufficient binding region:22-130 - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q99460-1 uniprotkb:Q9JKV1 intact:EBI-15703973|ensembl:ENSP00000309474|ensembl:ENSP00000503068 intact:EBI-8762776|uniprotkb:Q3UKZ8|uniprotkb:Q8BPH8|uniprotkb:Q922A7|ensembl:ENSMUSP00000050076 psi-mi:q99460-1(display_long)|uniprotkb:PSMD1(gene name)|psi-mi:PSMD1(display_short)|uniprotkb:26S proteasome regulatory subunit RPN2(gene name synonym)|uniprotkb:26S proteasome regulatory subunit S1(gene name synonym)|uniprotkb:26S proteasome subunit p112(gene name synonym) psi-mi:adrm1_mouse(display_long)|uniprotkb:Adrm1(gene name)|psi-mi:Adrm1(display_short)|uniprotkb:Gp110(gene name synonym)|uniprotkb:110 kDa cell membrane glycoprotein(gene name synonym)|uniprotkb:Adhesion-regulating molecule 1(gene name synonym)|uniprotkb:Rpn13 homolog(gene name synonym) psi-mi:"MI:0096"(pull down) Schreiner et al. (2008) pubmed:18497827|doi:10.1038/nature06924|imex:IM-21990 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15704199|imex:IM-21990-3|dip:DIP-195718E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000173692(gene)|ensembl:ENST00000308696(transcript)|ensembl:ENST00000677230(transcript)|intact:EBI-357874(isoform-parent) refseq:NP_062796.2|rcsb pdb:2R2Y|rcsb pdb:2Z59|reactome:R-MMU-5689603|reactome:R-MMU-5689880|ensembl:ENSMUSG00000039041(gene)|ensembl:ENSMUST00000061437(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0001541"(ovarian follicle development)|go:"GO:0002020"(protease binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007286"(spermatid development)|go:"GO:0008541"(proteasome regulatory particle, lid subcomplex)|go:"GO:0033081"(regulation of T cell differentiation in thymus)|go:"GO:0042699"(follicle-stimulating hormone signaling pathway)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043248"(proteasome assembly)|go:"GO:0048477"(oogenesis)|go:"GO:0048538"(thymus development)|go:"GO:0060009"(Sertoli cell development)|go:"GO:0060399"(positive regulation of growth hormone receptor signaling pathway)|go:"GO:0060612"(adipose tissue development)|go:"GO:0061133"(endopeptidase activator activity)|go:"GO:0070628"(proteasome binding)|go:"GO:0072520"(seminiferous tubule development)|interpro:IPR006773(Adhesion regulating molecule)|interpro:IPR032368|interpro:IPR038108|interpro:IPR038633|interpro:IPR044867|interpro:IPR044868|dip:DIP-60625N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/05 2017/08/10 rogid:aGYxoT30PhzvF/CiurQLDb8Ewrs9606 rogid:Pq49mSSQ2aSkNE/UB63ORYtBOIc10090 rigid:2IbuK1PaSRz7v3IWpuiGD+SH91s false sufficient binding region:902-953|glutathione s tranferase tag:?-? myc tag:n-n|sufficient binding region:1-150 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9JKV1 intact:EBI-4399559 intact:EBI-8762776|uniprotkb:Q3UKZ8|uniprotkb:Q8BPH8|uniprotkb:Q922A7|ensembl:ENSMUSP00000050076 dip:DIP-24261N psi-mi:adrm1_mouse(display_long)|uniprotkb:Adrm1(gene name)|psi-mi:Adrm1(display_short)|uniprotkb:Gp110(gene name synonym)|uniprotkb:110 kDa cell membrane glycoprotein(gene name synonym)|uniprotkb:Adhesion-regulating molecule 1(gene name synonym)|uniprotkb:Rpn13 homolog(gene name synonym) psi-mi:ubiq_human(display_short)|psi-mi:EBI-4399559(display_long) psi-mi:"MI:0096"(pull down) Schreiner et al. (2008) pubmed:18497827|doi:10.1038/nature06924|imex:IM-21990 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15704226|imex:IM-21990-4|dip:DIP-195717E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062796.2|rcsb pdb:2R2Y|rcsb pdb:2Z59|reactome:R-MMU-5689603|reactome:R-MMU-5689880|ensembl:ENSMUSG00000039041(gene)|ensembl:ENSMUST00000061437(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0001541"(ovarian follicle development)|go:"GO:0002020"(protease binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007286"(spermatid development)|go:"GO:0008541"(proteasome regulatory particle, lid subcomplex)|go:"GO:0033081"(regulation of T cell differentiation in thymus)|go:"GO:0042699"(follicle-stimulating hormone signaling pathway)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043248"(proteasome assembly)|go:"GO:0048477"(oogenesis)|go:"GO:0048538"(thymus development)|go:"GO:0060009"(Sertoli cell development)|go:"GO:0060399"(positive regulation of growth hormone receptor signaling pathway)|go:"GO:0060612"(adipose tissue development)|go:"GO:0061133"(endopeptidase activator activity)|go:"GO:0070628"(proteasome binding)|go:"GO:0072520"(seminiferous tubule development)|interpro:IPR006773(Adhesion regulating molecule)|interpro:IPR032368|interpro:IPR038108|interpro:IPR038633|interpro:IPR044867|interpro:IPR044868|dip:DIP-60625N uniprotkb:UBIQ_HUMAN(see-also)|refseq:NP_066289.2 psi-mi:"MI:0465"(dip) - no-uniprot-update: full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/05 2017/08/15 rogid:Pq49mSSQ2aSkNE/UB63ORYtBOIc10090 rogid:dobaeYpohKyDSnm4fBbcy0ZbYwM9606 rigid:hB2Gt4DukTSzLm6lzYTNes9oAUQ false sufficient binding region:1-150|mutation disrupting interaction strength:56-56|mutation disrupting interaction strength:76-76|mutation decreasing interaction strength:79-79|mutation disrupting interaction strength:75-75|mutation disrupting interaction strength:98-98|glutathione s tranferase tag:n-n|mutation decreasing interaction strength:55-55 - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)