#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q9R1P4 uniprotkb:Q9JII7 intact:EBI-991653|ensembl:ENSMUSP00000033008 intact:EBI-15701776|ensembl:ENSMUSP00000078910|ensembl:ENSMUSP00000106475 psi-mi:psa1_mouse(display_long)|uniprotkb:Proteasome component C2(gene name synonym)|uniprotkb:Macropain subunit C2(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex subunit C2(gene name synonym)|uniprotkb:Proteasome nu chain(gene name synonym)|uniprotkb:Psma1(gene name)|psi-mi:Psma1(display_short) psi-mi:zfn2a_mouse(display_long)|uniprotkb:Zfand2a(gene name)|psi-mi:Zfand2a(display_short)|uniprotkb:Airap(gene name synonym)|uniprotkb:Arsenite-inducible RNA-associated protein(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Yun et al. (2008) pubmed:18467495|doi:10.1073/pnas.0707025105|imex:IM-9340 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-15701798|imex:IM-9340-1|dip:DIP-87860E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR023332|interpro:IPR029055|interpro:IPR035144|mint:Q9R1P4|rcsb pdb:3UNB|rcsb pdb:3UNE|rcsb pdb:3UNF|rcsb pdb:3UNH|reactome:R-MMU-1169091|reactome:R-MMU-1234176|reactome:R-MMU-1236978|reactome:R-MMU-174084|reactome:R-MMU-174154|reactome:R-MMU-174178|reactome:R-MMU-174184|reactome:R-MMU-187577|reactome:R-MMU-195253|reactome:R-MMU-202424|reactome:R-MMU-2467813|reactome:R-MMU-2871837|reactome:R-MMU-349425|reactome:R-MMU-350562|reactome:R-MMU-382556|reactome:R-MMU-450408|reactome:R-MMU-4608870|reactome:R-MMU-4641257|reactome:R-MMU-4641258|reactome:R-MMU-5358346|reactome:R-MMU-5607761|reactome:R-MMU-5607764|reactome:R-MMU-5610780|reactome:R-MMU-5610785|reactome:R-MMU-5632684|reactome:R-MMU-5658442|reactome:R-MMU-5668541|reactome:R-MMU-5676590|reactome:R-MMU-5687128|reactome:R-MMU-5689603|reactome:R-MMU-5689880|reactome:R-MMU-68827|reactome:R-MMU-68949|reactome:R-MMU-69017|reactome:R-MMU-69481|reactome:R-MMU-69601|reactome:R-MMU-75815|reactome:R-MMU-8852276|reactome:R-MMU-8854050|reactome:R-MMU-8932339|reactome:R-MMU-8939236|reactome:R-MMU-8939902|reactome:R-MMU-8941858|go:"GO:0005829"(cytosol)|reactome:R-MMU-8948751|reactome:R-MMU-8951664|reactome:R-MMU-9020702|reactome:R-MMU-983168|ensembl:ENSMUSG00000030751(gene)|ensembl:ENSMUST00000033008(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0001530"(lipopolysaccharide binding)|go:"GO:0002376"(immune system process)|go:"GO:0002862"(negative regulation of inflammatory response to antigenic stimulus)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|refseq:NP_036095.1|dip:DIP-35147N ensembl:ENSMUSG00000053581(gene)|ensembl:ENSMUST00000079996(transcript)|ensembl:ENSMUST00000110851(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0008270"(zinc ion binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045047"(protein targeting to ER)|go:"GO:0071243"(cellular response to arsenic-containing substance)|interpro:IPR000058(Zinc finger, AN1-type)|interpro:IPR035896|refseq:NP_001153380.1|refseq:NP_579927.1|dip:DIP-46092N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse)|taxid:10090(Mus musculus) - 2017/08/05 2017/08/10 rogid:5AV1kxiJdOzf5jh1YRmUL94hQwk10090 rogid:HSk2Oj4nfhnSXX/llhf1SiB9+vI10090 rigid:mmj8nXiuzAiAPl59eywvOH9svRM false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9R1P4 uniprotkb:Q91X58 intact:EBI-991653|ensembl:ENSMUSP00000033008 intact:EBI-15701753|ensembl:ENSMUSP00000027394|ensembl:ENSMUSP00000125086|uniprotkb:Q9D0W4 psi-mi:psa1_mouse(display_long)|uniprotkb:Proteasome component C2(gene name synonym)|uniprotkb:Macropain subunit C2(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex subunit C2(gene name synonym)|uniprotkb:Proteasome nu chain(gene name synonym)|uniprotkb:Psma1(gene name)|psi-mi:Psma1(display_short) psi-mi:zfn2b_mouse(display_long)|uniprotkb:Zfand2b(gene name)|psi-mi:Zfand2b(display_short)|uniprotkb:Airapl(gene name synonym)|uniprotkb:Arsenite-inducible RNA-associated protein-like protein(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Yun et al. (2008) pubmed:18467495|doi:10.1073/pnas.0707025105|imex:IM-9340 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-15701798|imex:IM-9340-1|dip:DIP-87860E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR023332|interpro:IPR029055|interpro:IPR035144|mint:Q9R1P4|rcsb pdb:3UNB|rcsb pdb:3UNE|rcsb pdb:3UNF|rcsb pdb:3UNH|reactome:R-MMU-1169091|reactome:R-MMU-1234176|reactome:R-MMU-1236978|reactome:R-MMU-174084|reactome:R-MMU-174154|reactome:R-MMU-174178|reactome:R-MMU-174184|reactome:R-MMU-187577|reactome:R-MMU-195253|reactome:R-MMU-202424|reactome:R-MMU-2467813|reactome:R-MMU-2871837|reactome:R-MMU-349425|reactome:R-MMU-350562|reactome:R-MMU-382556|reactome:R-MMU-450408|reactome:R-MMU-4608870|reactome:R-MMU-4641257|reactome:R-MMU-4641258|reactome:R-MMU-5358346|reactome:R-MMU-5607761|reactome:R-MMU-5607764|reactome:R-MMU-5610780|reactome:R-MMU-5610785|reactome:R-MMU-5632684|reactome:R-MMU-5658442|reactome:R-MMU-5668541|reactome:R-MMU-5676590|reactome:R-MMU-5687128|reactome:R-MMU-5689603|reactome:R-MMU-5689880|reactome:R-MMU-68827|reactome:R-MMU-68949|reactome:R-MMU-69017|reactome:R-MMU-69481|reactome:R-MMU-69601|reactome:R-MMU-75815|reactome:R-MMU-8852276|reactome:R-MMU-8854050|reactome:R-MMU-8932339|reactome:R-MMU-8939236|reactome:R-MMU-8939902|reactome:R-MMU-8941858|go:"GO:0005829"(cytosol)|reactome:R-MMU-8948751|reactome:R-MMU-8951664|reactome:R-MMU-9020702|reactome:R-MMU-983168|ensembl:ENSMUSG00000030751(gene)|ensembl:ENSMUST00000033008(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0001530"(lipopolysaccharide binding)|go:"GO:0002376"(immune system process)|go:"GO:0002862"(negative regulation of inflammatory response to antigenic stimulus)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|refseq:NP_036095.1|dip:DIP-35147N ensembl:ENSMUSG00000026197(gene)|ensembl:ENSMUST00000027394(transcript)|ensembl:ENSMUST00000160439(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006616"(SRP-dependent cotranslational protein targeting to membrane, translocation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0031225"(anchored component of membrane)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0036435"(K48-linked polyubiquitin modification-dependent protein binding)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043567"(regulation of insulin-like growth factor receptor signaling pathway)|go:"GO:0045047"(protein targeting to ER)|interpro:IPR000058(Zinc finger, AN1-type)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR035896|rcsb pdb:4XKH|refseq:NP_001153377.1|refseq:NP_001153378.1|refseq:NP_081122.2|dip:DIP-46091N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse)|taxid:10090(Mus musculus) - 2017/08/05 2017/08/10 rogid:5AV1kxiJdOzf5jh1YRmUL94hQwk10090 rogid:wjpx1mjdHgppgLpNks2Z0QOyI6810090 rigid:mmj8nXiuzAiAPl59eywvOH9svRM false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9JII7 uniprotkb:P25786 intact:EBI-15701776|ensembl:ENSMUSP00000078910|ensembl:ENSMUSP00000106475 intact:EBI-359352|uniprotkb:Q9BRV9|uniprotkb:A8K400|uniprotkb:Q53YE8|ensembl:ENSP00000379676 psi-mi:zfn2a_mouse(display_long)|uniprotkb:Zfand2a(gene name)|psi-mi:Zfand2a(display_short)|uniprotkb:Airap(gene name synonym)|uniprotkb:Arsenite-inducible RNA-associated protein(gene name synonym) psi-mi:psa1_human(display_long)|uniprotkb:PSMA1(gene name)|psi-mi:PSMA1(display_short)|uniprotkb:PROS30(gene name synonym)|uniprotkb:PSC2(gene name synonym)|uniprotkb:Proteasome component C2(gene name synonym)|uniprotkb:Macropain subunit C2(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex subunit C2(gene name synonym)|uniprotkb:Proteasome nu chain(gene name synonym)|uniprotkb:30 kDa prosomal protein(gene name synonym)|uniprotkb:HC2(gene name synonym)|uniprotkb:NU(gene name synonym) psi-mi:"MI:0096"(pull down) Yun et al. (2008) pubmed:18467495|doi:10.1073/pnas.0707025105|imex:IM-9340 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15701816|imex:IM-9340-2|dip:DIP-87863E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000053581(gene)|ensembl:ENSMUST00000079996(transcript)|ensembl:ENSMUST00000110851(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0008270"(zinc ion binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045047"(protein targeting to ER)|go:"GO:0071243"(cellular response to arsenic-containing substance)|interpro:IPR000058(Zinc finger, AN1-type)|interpro:IPR035896|refseq:NP_001153380.1|refseq:NP_579927.1|dip:DIP-46092N refseq:NP_002777.1|refseq:NP_683877.1|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFO|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:6AVO|rcsb pdb:6E5B|rcsb pdb:6KWY|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6R70|rcsb pdb:6REY|rcsb pdb:6RGQ|rcsb pdb:6WJD|rcsb pdb:6WJN|rcsb pdb:6XMJ|rcsb pdb:7AWE|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|ensembl:ENSG00000129084(gene)|ensembl:ENST00000396394(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0002376"(immune system process)|go:"GO:0003723"(RNA binding)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0005844"(polysome)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR023332|interpro:IPR029055|interpro:IPR035144|mint:P25786|rcsb pdb:4R3O|rcsb pdb:4R67|rcsb pdb:5A0Q|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LE5|rcsb pdb:5LEX|rcsb pdb:5LEY|rcsb pdb:5LEZ|rcsb pdb:5LF0|rcsb pdb:5LF1|rcsb pdb:5LF3|rcsb pdb:5LF4|rcsb pdb:5LF6|rcsb pdb:5LF7|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|dip:DIP-29369N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/05 2017/08/10 rogid:HSk2Oj4nfhnSXX/llhf1SiB9+vI10090 rogid:tAADzZ1G9E/0BBeS8vybNx97v7k9606 rigid:xD2iqLRONaa7jhxo8VM/CYQkVr8 false glutathione s tranferase tag:c-c - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9R1P4 uniprotkb:Q91X58 intact:EBI-991653|ensembl:ENSMUSP00000033008 intact:EBI-15701753|ensembl:ENSMUSP00000027394|ensembl:ENSMUSP00000125086|uniprotkb:Q9D0W4 psi-mi:psa1_mouse(display_long)|uniprotkb:Proteasome component C2(gene name synonym)|uniprotkb:Macropain subunit C2(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex subunit C2(gene name synonym)|uniprotkb:Proteasome nu chain(gene name synonym)|uniprotkb:Psma1(gene name)|psi-mi:Psma1(display_short) psi-mi:zfn2b_mouse(display_long)|uniprotkb:Zfand2b(gene name)|psi-mi:Zfand2b(display_short)|uniprotkb:Airapl(gene name synonym)|uniprotkb:Arsenite-inducible RNA-associated protein-like protein(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Yun et al. (2008) pubmed:18467495|doi:10.1073/pnas.0707025105|imex:IM-9340 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15701835|imex:IM-9340-3|dip:DIP-87861E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR023332|interpro:IPR029055|interpro:IPR035144|mint:Q9R1P4|rcsb pdb:3UNB|rcsb pdb:3UNE|rcsb pdb:3UNF|rcsb pdb:3UNH|reactome:R-MMU-1169091|reactome:R-MMU-1234176|reactome:R-MMU-1236978|reactome:R-MMU-174084|reactome:R-MMU-174154|reactome:R-MMU-174178|reactome:R-MMU-174184|reactome:R-MMU-187577|reactome:R-MMU-195253|reactome:R-MMU-202424|reactome:R-MMU-2467813|reactome:R-MMU-2871837|reactome:R-MMU-349425|reactome:R-MMU-350562|reactome:R-MMU-382556|reactome:R-MMU-450408|reactome:R-MMU-4608870|reactome:R-MMU-4641257|reactome:R-MMU-4641258|reactome:R-MMU-5358346|reactome:R-MMU-5607761|reactome:R-MMU-5607764|reactome:R-MMU-5610780|reactome:R-MMU-5610785|reactome:R-MMU-5632684|reactome:R-MMU-5658442|reactome:R-MMU-5668541|reactome:R-MMU-5676590|reactome:R-MMU-5687128|reactome:R-MMU-5689603|reactome:R-MMU-5689880|reactome:R-MMU-68827|reactome:R-MMU-68949|reactome:R-MMU-69017|reactome:R-MMU-69481|reactome:R-MMU-69601|reactome:R-MMU-75815|reactome:R-MMU-8852276|reactome:R-MMU-8854050|reactome:R-MMU-8932339|reactome:R-MMU-8939236|reactome:R-MMU-8939902|reactome:R-MMU-8941858|go:"GO:0005829"(cytosol)|reactome:R-MMU-8948751|reactome:R-MMU-8951664|reactome:R-MMU-9020702|reactome:R-MMU-983168|ensembl:ENSMUSG00000030751(gene)|ensembl:ENSMUST00000033008(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0001530"(lipopolysaccharide binding)|go:"GO:0002376"(immune system process)|go:"GO:0002862"(negative regulation of inflammatory response to antigenic stimulus)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|refseq:NP_036095.1|dip:DIP-35147N ensembl:ENSMUSG00000026197(gene)|ensembl:ENSMUST00000027394(transcript)|ensembl:ENSMUST00000160439(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006616"(SRP-dependent cotranslational protein targeting to membrane, translocation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0031225"(anchored component of membrane)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0036435"(K48-linked polyubiquitin modification-dependent protein binding)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043567"(regulation of insulin-like growth factor receptor signaling pathway)|go:"GO:0045047"(protein targeting to ER)|interpro:IPR000058(Zinc finger, AN1-type)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR035896|rcsb pdb:4XKH|refseq:NP_001153377.1|refseq:NP_001153378.1|refseq:NP_081122.2|dip:DIP-46091N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse)|taxid:10090(Mus musculus) - 2017/08/05 2017/08/10 rogid:5AV1kxiJdOzf5jh1YRmUL94hQwk10090 rogid:wjpx1mjdHgppgLpNks2Z0QOyI6810090 rigid:b9C+XU5FT/blMpSGvfZgPIY3Mgs false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) intact:EBI-15701852 uniprotkb:P25786 dip:DIP-46093N intact:EBI-359352|uniprotkb:Q9BRV9|uniprotkb:A8K400|uniprotkb:Q53YE8|ensembl:ENSP00000379676 psi-mi:aal.140(display_short)|psi-mi:EBI-15701852(display_long) psi-mi:psa1_human(display_long)|uniprotkb:PSMA1(gene name)|psi-mi:PSMA1(display_short)|uniprotkb:PROS30(gene name synonym)|uniprotkb:PSC2(gene name synonym)|uniprotkb:Proteasome component C2(gene name synonym)|uniprotkb:Macropain subunit C2(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex subunit C2(gene name synonym)|uniprotkb:Proteasome nu chain(gene name synonym)|uniprotkb:30 kDa prosomal protein(gene name synonym)|uniprotkb:HC2(gene name synonym)|uniprotkb:NU(gene name synonym) psi-mi:"MI:0096"(pull down) Yun et al. (2008) pubmed:18467495|doi:10.1073/pnas.0707025105|imex:IM-9340 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15701855|imex:IM-9340-4|dip:DIP-87864E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - refseq:NP_002777.1|refseq:NP_683877.1|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFO|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:6AVO|rcsb pdb:6E5B|rcsb pdb:6KWY|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6R70|rcsb pdb:6REY|rcsb pdb:6RGQ|rcsb pdb:6WJD|rcsb pdb:6WJN|rcsb pdb:6XMJ|rcsb pdb:7AWE|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|ensembl:ENSG00000129084(gene)|ensembl:ENST00000396394(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0002376"(immune system process)|go:"GO:0003723"(RNA binding)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0005844"(polysome)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR023332|interpro:IPR029055|interpro:IPR035144|mint:P25786|rcsb pdb:4R3O|rcsb pdb:4R67|rcsb pdb:5A0Q|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LE5|rcsb pdb:5LEX|rcsb pdb:5LEY|rcsb pdb:5LEZ|rcsb pdb:5LF0|rcsb pdb:5LF1|rcsb pdb:5LF3|rcsb pdb:5LF4|rcsb pdb:5LF6|rcsb pdb:5LF7|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|dip:DIP-29369N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/05 2017/08/10 rogid:Y5A30aVToxn1rX6JNKd2htaNkBY-2 rogid:tAADzZ1G9E/0BBeS8vybNx97v7k9606 rigid:yNdccZfYs8FWfjLru/r5AoxRrEk false glutathione s tranferase tag:0-0 - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P25786 uniprotkb:Q91X58 intact:EBI-359352|uniprotkb:Q9BRV9|uniprotkb:A8K400|uniprotkb:Q53YE8|ensembl:ENSP00000379676 intact:EBI-15701753|ensembl:ENSMUSP00000027394|ensembl:ENSMUSP00000125086|uniprotkb:Q9D0W4 psi-mi:psa1_human(display_long)|uniprotkb:PSMA1(gene name)|psi-mi:PSMA1(display_short)|uniprotkb:PROS30(gene name synonym)|uniprotkb:PSC2(gene name synonym)|uniprotkb:Proteasome component C2(gene name synonym)|uniprotkb:Macropain subunit C2(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex subunit C2(gene name synonym)|uniprotkb:Proteasome nu chain(gene name synonym)|uniprotkb:30 kDa prosomal protein(gene name synonym)|uniprotkb:HC2(gene name synonym)|uniprotkb:NU(gene name synonym) psi-mi:zfn2b_mouse(display_long)|uniprotkb:Zfand2b(gene name)|psi-mi:Zfand2b(display_short)|uniprotkb:Airapl(gene name synonym)|uniprotkb:Arsenite-inducible RNA-associated protein-like protein(gene name synonym) psi-mi:"MI:0096"(pull down) Yun et al. (2008) pubmed:18467495|doi:10.1073/pnas.0707025105|imex:IM-9340 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15701874|imex:IM-9340-5|dip:DIP-87862E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002777.1|refseq:NP_683877.1|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFO|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:6AVO|rcsb pdb:6E5B|rcsb pdb:6KWY|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6R70|rcsb pdb:6REY|rcsb pdb:6RGQ|rcsb pdb:6WJD|rcsb pdb:6WJN|rcsb pdb:6XMJ|rcsb pdb:7AWE|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|ensembl:ENSG00000129084(gene)|ensembl:ENST00000396394(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0002376"(immune system process)|go:"GO:0003723"(RNA binding)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0005844"(polysome)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR023332|interpro:IPR029055|interpro:IPR035144|mint:P25786|rcsb pdb:4R3O|rcsb pdb:4R67|rcsb pdb:5A0Q|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LE5|rcsb pdb:5LEX|rcsb pdb:5LEY|rcsb pdb:5LEZ|rcsb pdb:5LF0|rcsb pdb:5LF1|rcsb pdb:5LF3|rcsb pdb:5LF4|rcsb pdb:5LF6|rcsb pdb:5LF7|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|dip:DIP-29369N ensembl:ENSMUSG00000026197(gene)|ensembl:ENSMUST00000027394(transcript)|ensembl:ENSMUST00000160439(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006616"(SRP-dependent cotranslational protein targeting to membrane, translocation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0031225"(anchored component of membrane)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0036435"(K48-linked polyubiquitin modification-dependent protein binding)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043567"(regulation of insulin-like growth factor receptor signaling pathway)|go:"GO:0045047"(protein targeting to ER)|interpro:IPR000058(Zinc finger, AN1-type)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR035896|rcsb pdb:4XKH|refseq:NP_001153377.1|refseq:NP_001153378.1|refseq:NP_081122.2|dip:DIP-46091N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/05 2017/08/10 rogid:tAADzZ1G9E/0BBeS8vybNx97v7k9606 rogid:wjpx1mjdHgppgLpNks2Z0QOyI6810090 rigid:l0JrFoFUotHzbhC2V8orJ9fxScw false - glutathione s tranferase tag:c-c - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot)