#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q14061 uniprotkb:O75880 intact:EBI-711311|uniprotkb:D3DN84|ensembl:ENSP00000261070|ensembl:ENSP00000417805|ensembl:ENSP00000417923|uniprotkb:Q3MHD6|uniprotkb:B2R5D2 intact:EBI-6656171|ensembl:ENSP00000255390|uniprotkb:B2RDM0 psi-mi:cox17_human(display_long)|uniprotkb:COX17(gene name)|psi-mi:COX17(display_short) psi-mi:sco1_human(display_long)|uniprotkb:SCO1(gene name)|psi-mi:SCO1(display_short)|uniprotkb:SCOD1(gene name synonym) psi-mi:"MI:0077"(nuclear magnetic resonance) Banci et al. (2008) pubmed:18458339|doi:10.1073/pnas.0800019105|imex:IM-9335 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15700412|imex:IM-9335-1|dip:DIP-87850E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005685.1|ensembl:ENSG00000138495(gene)|ensembl:ENST00000261070(transcript)|ensembl:ENST00000468918(transcript)|ensembl:ENST00000497116(transcript)|go:"GO:0005507"(copper ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0006091"(generation of precursor metabolites and energy)|go:"GO:0006825"(copper ion transport)|go:"GO:0007420"(brain development)|go:"GO:0007507"(heart development)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016531"(copper chaperone activity)|go:"GO:0033617"(mitochondrial cytochrome c oxidase assembly)|go:"GO:1903136"(cuprous ion binding)|go:"GO:1904960"(positive regulation of cytochrome-c oxidase activity)|interpro:IPR007745(Cytochrome C oxidase copper chaperone)|interpro:IPR009069(MTCP1)|rcsb pdb:2L0Y|rcsb pdb:2LGQ|rcsb pdb:2RN9|rcsb pdb:2RNB|reactome:R-HSA-1268020|dip:DIP-46087N ensembl:ENSG00000133028(gene)|ensembl:ENST00000255390(transcript)|go:"GO:0005507"(copper ion binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0006878"(cellular copper ion homeostasis)|go:"GO:0016531"(copper chaperone activity)|go:"GO:0030016"(myofibril)|go:"GO:0031305"(integral component of mitochondrial inner membrane)|go:"GO:0033617"(mitochondrial cytochrome c oxidase assembly)|interpro:IPR003782(Copper chaperone SCO1/SenC)|interpro:IPR017276(Synthesis of cytochrome c oxidase, Sco1/Sco2)|interpro:IPR036249|rcsb pdb:1WP0|rcsb pdb:2GGT|rcsb pdb:2GQK|rcsb pdb:2GQL|rcsb pdb:2GQM|rcsb pdb:2GT5|rcsb pdb:2GT6|rcsb pdb:2GVP|rcsb pdb:2HRF|rcsb pdb:2HRN|reactome:R-HSA-5628897|reactome:R-HSA-611105|reactome:R-HSA-9707564|refseq:NP_004580.1|dip:DIP-46086N|refseq:XP_005256808.1 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/05 2017/08/10 rogid:DduAgG449PBuqu3MF3MBChmg6t09606 rogid:oxGxX5mXuGDP5uPIW1vyOtaQHxU9606 rigid:djBBE0Hku3NVu+wCOvwxOjeHP+A false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O43819 uniprotkb:Q14061 intact:EBI-357012|uniprotkb:Q3T1B5|uniprotkb:Q9UK87|ensembl:ENSP00000252785|ensembl:ENSP00000379046|ensembl:ENSP00000444242|ensembl:ENSP00000444433 intact:EBI-711311|uniprotkb:D3DN84|ensembl:ENSP00000261070|ensembl:ENSP00000417805|ensembl:ENSP00000417923|uniprotkb:Q3MHD6|uniprotkb:B2R5D2 psi-mi:sco2_human(display_long)|uniprotkb:SCO2(gene name)|psi-mi:SCO2(display_short) psi-mi:cox17_human(display_long)|uniprotkb:COX17(gene name)|psi-mi:COX17(display_short) psi-mi:"MI:0077"(nuclear magnetic resonance) Banci et al. (2008) pubmed:18458339|doi:10.1073/pnas.0800019105|imex:IM-9335 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15700429|imex:IM-9335-2|dip:DIP-87851E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001162580.1|refseq:NP_001162581.1|refseq:NP_001162582.1|refseq:NP_005129.2|dip:DIP-46088N|go:"GO:0003012"(muscle system process)|go:"GO:0005507"(copper ion binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006878"(cellular copper ion homeostasis)|go:"GO:0014823"(response to activity)|go:"GO:0015035"(protein-disulfide reductase activity)|go:"GO:0016531"(copper chaperone activity)|go:"GO:0022904"(respiratory electron transport chain)|go:"GO:0030016"(myofibril)|go:"GO:0031305"(integral component of mitochondrial inner membrane)|go:"GO:0033617"(mitochondrial cytochrome c oxidase assembly)|interpro:IPR003782(Copper chaperone SCO1/SenC)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR017276(Synthesis of cytochrome c oxidase, Sco1/Sco2)|interpro:IPR036249|mint:O43819|rcsb pdb:2RLI|reactome:R-HSA-5628897|reactome:R-HSA-611105|reactome:R-HSA-9707564|ensembl:ENSG00000284194(gene)|ensembl:ENST00000252785(transcript)|ensembl:ENST00000395693(transcript)|ensembl:ENST00000535425(transcript)|ensembl:ENST00000543927(transcript)|go:"GO:0001654"(eye development)|go:"GO:0001701"(in utero embryonic development) refseq:NP_005685.1|ensembl:ENSG00000138495(gene)|ensembl:ENST00000261070(transcript)|ensembl:ENST00000468918(transcript)|ensembl:ENST00000497116(transcript)|go:"GO:0005507"(copper ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0006091"(generation of precursor metabolites and energy)|go:"GO:0006825"(copper ion transport)|go:"GO:0007420"(brain development)|go:"GO:0007507"(heart development)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016531"(copper chaperone activity)|go:"GO:0033617"(mitochondrial cytochrome c oxidase assembly)|go:"GO:1903136"(cuprous ion binding)|go:"GO:1904960"(positive regulation of cytochrome-c oxidase activity)|interpro:IPR007745(Cytochrome C oxidase copper chaperone)|interpro:IPR009069(MTCP1)|rcsb pdb:2L0Y|rcsb pdb:2LGQ|rcsb pdb:2RN9|rcsb pdb:2RNB|reactome:R-HSA-1268020|dip:DIP-46087N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/05 2017/08/10 rogid:RaD9DPaOnFKJvwNRUK9KQdptmqc9606 rogid:DduAgG449PBuqu3MF3MBChmg6t09606 rigid:kdMPnf6Od0pk5L9phqFseDJTXYQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q14061 uniprotkb:O75880 intact:EBI-711311|uniprotkb:D3DN84|ensembl:ENSP00000261070|ensembl:ENSP00000417805|ensembl:ENSP00000417923|uniprotkb:Q3MHD6|uniprotkb:B2R5D2 intact:EBI-6656171|ensembl:ENSP00000255390|uniprotkb:B2RDM0 psi-mi:cox17_human(display_long)|uniprotkb:COX17(gene name)|psi-mi:COX17(display_short) psi-mi:sco1_human(display_long)|uniprotkb:SCO1(gene name)|psi-mi:SCO1(display_short)|uniprotkb:SCOD1(gene name synonym) psi-mi:"MI:0069"(mass spectrometry studies of complexes) Banci et al. (2008) pubmed:18458339|doi:10.1073/pnas.0800019105|imex:IM-9335 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15700446|imex:IM-9335-3|dip:DIP-87850E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005685.1|ensembl:ENSG00000138495(gene)|ensembl:ENST00000261070(transcript)|ensembl:ENST00000468918(transcript)|ensembl:ENST00000497116(transcript)|go:"GO:0005507"(copper ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0006091"(generation of precursor metabolites and energy)|go:"GO:0006825"(copper ion transport)|go:"GO:0007420"(brain development)|go:"GO:0007507"(heart development)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016531"(copper chaperone activity)|go:"GO:0033617"(mitochondrial cytochrome c oxidase assembly)|go:"GO:1903136"(cuprous ion binding)|go:"GO:1904960"(positive regulation of cytochrome-c oxidase activity)|interpro:IPR007745(Cytochrome C oxidase copper chaperone)|interpro:IPR009069(MTCP1)|rcsb pdb:2L0Y|rcsb pdb:2LGQ|rcsb pdb:2RN9|rcsb pdb:2RNB|reactome:R-HSA-1268020|dip:DIP-46087N ensembl:ENSG00000133028(gene)|ensembl:ENST00000255390(transcript)|go:"GO:0005507"(copper ion binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0006878"(cellular copper ion homeostasis)|go:"GO:0016531"(copper chaperone activity)|go:"GO:0030016"(myofibril)|go:"GO:0031305"(integral component of mitochondrial inner membrane)|go:"GO:0033617"(mitochondrial cytochrome c oxidase assembly)|interpro:IPR003782(Copper chaperone SCO1/SenC)|interpro:IPR017276(Synthesis of cytochrome c oxidase, Sco1/Sco2)|interpro:IPR036249|rcsb pdb:1WP0|rcsb pdb:2GGT|rcsb pdb:2GQK|rcsb pdb:2GQL|rcsb pdb:2GQM|rcsb pdb:2GT5|rcsb pdb:2GT6|rcsb pdb:2GVP|rcsb pdb:2HRF|rcsb pdb:2HRN|reactome:R-HSA-5628897|reactome:R-HSA-611105|reactome:R-HSA-9707564|refseq:NP_004580.1|dip:DIP-46086N|refseq:XP_005256808.1 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/05 2017/08/10 rogid:DduAgG449PBuqu3MF3MBChmg6t09606 rogid:oxGxX5mXuGDP5uPIW1vyOtaQHxU9606 rigid:djBBE0Hku3NVu+wCOvwxOjeHP+A false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)