#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P25976 uniprotkb:P10085 intact:EBI-7364139|intact:MINT-4084181 intact:EBI-4405734|uniprotkb:Q8C6B1|ensembl:ENSMUSP00000072330 psi-mi:ubf1_mouse(display_long)|uniprotkb:Ubtf(gene name)|psi-mi:Ubtf(display_short)|uniprotkb:Tcfubf(gene name synonym)|uniprotkb:Ubf1(gene name synonym)|uniprotkb:Ubf-1(gene name synonym)|uniprotkb:Upstream-binding factor 1(gene name synonym) psi-mi:myod1_mouse(display_long)|uniprotkb:Myod1(gene name)|psi-mi:Myod1(display_short)|uniprotkb:Myod(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Ali et al. (2008) pubmed:18445650|doi:10.1073/pnas.0800970105|imex:IM-9263 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15699667|imex:IM-9263-2|dip:DIP-59506E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:P25976|go:"GO:0001164"(RNA polymerase I core promoter sequence-specific DNA binding)|go:"GO:0001165"(RNA polymerase I cis-regulatory region sequence-specific DNA binding)|go:"GO:0001181"(RNA polymerase I general transcription initiation factor activity)|go:"GO:0001650"(fibrillar center)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0006360"(transcription by RNA polymerase I)|go:"GO:0006361"(transcription initiation from RNA polymerase I promoter)|go:"GO:0006362"(transcription elongation from RNA polymerase I promoter)|go:"GO:0045943"(positive regulation of transcription by RNA polymerase I)|go:"GO:0097110"(scaffold protein binding)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR029215|interpro:IPR036910|rcsb pdb:1V63|rcsb pdb:1V64|rcsb pdb:1WGF|reactome:R-MMU-73728|reactome:R-MMU-73762|reactome:R-MMU-73772|reactome:R-MMU-73863|dip:DIP-29977N refseq:NP_034996.2|dip:DIP-37N|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000785"(chromatin)|go:"GO:0000791"(euchromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007517"(muscle organ development)|go:"GO:0007518"(myoblast fate determination)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0014902"(myotube differentiation)|go:"GO:0014904"(myotube cell development)|go:"GO:0014908"(myotube differentiation involved in skeletal muscle regeneration)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030016"(myofibril)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035562"(negative regulation of chromatin binding)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043403"(skeletal muscle tissue regeneration)|go:"GO:0043415"(positive regulation of skeletal muscle tissue regeneration)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043503"(skeletal muscle fiber adaptation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0045445"(myoblast differentiation)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0045663"(positive regulation of myoblast differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0048741"(skeletal muscle fiber development)|go:"GO:0048743"(positive regulation of skeletal muscle fiber development)|go:"GO:0051099"(positive regulation of binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0051146"(striated muscle cell differentiation)|go:"GO:0051149"(positive regulation of muscle cell differentiation)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0055007"(cardiac muscle cell differentiation)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070888"(E-box binding)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071385"(cellular response to glucocorticoid stimulus)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:0071453"(cellular response to oxygen levels)|go:"GO:1901741"(positive regulation of myoblast fusion)|go:"GO:1905382"(positive regulation of snRNA transcription by RNA polymerase II)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000818"(negative regulation of myoblast proliferation)|interpro:IPR002546(Myogenic basic muscle-specific protein)|interpro:IPR011598(Helix-loop-helix DNA-binding)|ensembl:ENSMUSG00000009471(gene)|ensembl:ENSMUST00000072514(transcript)|interpro:IPR036638|interpro:IPR039704|mint:P10085|rcsb pdb:1MDY|reactome:R-MMU-525793|interpro:IPR022032 psi-mi:"MI:0465"(dip) comment:mint|function:UBF recognizes the ribosomal RNA gene promoter and activates transcription mediated by RNA polymerase I through cooperative interactions with the species-specific factor SL1. It binds specifically to the upstream control element - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse)|taxid:10090(Mus musculus) - 2017/08/05 2017/08/10 rogid:TJRBUUHHZDYhIRdbtsijzuOSbAo10090 rogid:9GpR7O8xYPiQXHqrlxB/HioqgJM10090 rigid:hfnkTnMEosUYGwXNB08h4C58EEA false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P25976 uniprotkb:P12979 intact:EBI-7364139|intact:MINT-4084181 intact:EBI-7132875|ensembl:ENSMUSP00000027730|intact:MINT-1958829 psi-mi:ubf1_mouse(display_long)|uniprotkb:Ubtf(gene name)|psi-mi:Ubtf(display_short)|uniprotkb:Tcfubf(gene name synonym)|uniprotkb:Ubf1(gene name synonym)|uniprotkb:Ubf-1(gene name synonym)|uniprotkb:Upstream-binding factor 1(gene name synonym) psi-mi:myog_mouse(display_long)|uniprotkb:Myog(gene name)|psi-mi:Myog(display_short)|uniprotkb:MYOD1-related protein(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Ali et al. (2008) pubmed:18445650|doi:10.1073/pnas.0800970105|imex:IM-9263 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15699684|imex:IM-9263-1|dip:DIP-59507E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:P25976|go:"GO:0001164"(RNA polymerase I core promoter sequence-specific DNA binding)|go:"GO:0001165"(RNA polymerase I cis-regulatory region sequence-specific DNA binding)|go:"GO:0001181"(RNA polymerase I general transcription initiation factor activity)|go:"GO:0001650"(fibrillar center)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0006360"(transcription by RNA polymerase I)|go:"GO:0006361"(transcription initiation from RNA polymerase I promoter)|go:"GO:0006362"(transcription elongation from RNA polymerase I promoter)|go:"GO:0045943"(positive regulation of transcription by RNA polymerase I)|go:"GO:0097110"(scaffold protein binding)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR029215|interpro:IPR036910|rcsb pdb:1V63|rcsb pdb:1V64|rcsb pdb:1WGF|reactome:R-MMU-73728|reactome:R-MMU-73762|reactome:R-MMU-73772|reactome:R-MMU-73863|dip:DIP-29977N ensembl:ENSMUSG00000026459(gene)|ensembl:ENSMUST00000027730(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001503"(ossification)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007049"(cell cycle)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014737"(positive regulation of muscle atrophy)|go:"GO:0014842"(regulation of skeletal muscle satellite cell proliferation)|go:"GO:0014873"(response to muscle activity involved in regulation of muscle adaptation)|go:"GO:0014878"(response to electrical stimulus involved in regulation of muscle adaptation)|go:"GO:0014891"(striated muscle atrophy)|go:"GO:0014894"(response to denervation involved in regulation of muscle adaptation)|go:"GO:0014902"(myotube differentiation)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0042692"(muscle cell differentiation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045663"(positive regulation of myoblast differentiation)|go:"GO:0045820"(negative regulation of glycolytic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048741"(skeletal muscle fiber development)|go:"GO:0048743"(positive regulation of skeletal muscle fiber development)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070888"(E-box binding)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:1901739"(regulation of myoblast fusion)|go:"GO:1903862"(positive regulation of oxidative phosphorylation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR002546(Myogenic basic muscle-specific protein)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|interpro:IPR039704|mint:P12979|reactome:R-MMU-525793|refseq:NP_112466.1|dip:DIP-29976N psi-mi:"MI:0465"(dip) comment:mint|function:UBF recognizes the ribosomal RNA gene promoter and activates transcription mediated by RNA polymerase I through cooperative interactions with the species-specific factor SL1. It binds specifically to the upstream control element comment:mint|function:"Involved in muscle differentiation (myogenic factor). Induces fibroblasts to differentiate into myoblasts. Probable sequence specific DNA-binding protein" full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse)|taxid:10090(Mus musculus) - 2017/08/05 2017/08/10 rogid:TJRBUUHHZDYhIRdbtsijzuOSbAo10090 rogid:l3clEJXowEpguOGcxOJfG13NXvU10090 rigid:URlea4SXPpcIUW0qgj3sS8Eiaas false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot)