#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P00451	uniprotkb:P00451	intact:EBI-1046394|ensembl:ENSP00000353393|uniprotkb:Q5HY69|uniprotkb:Q14286	intact:EBI-1046394|ensembl:ENSP00000353393|uniprotkb:Q5HY69|uniprotkb:Q14286	psi-mi:fa8_human(display_long)|uniprotkb:Procoagulant component(gene name synonym)|uniprotkb:Antihemophilic factor(gene name synonym)|uniprotkb:F8(gene name)|psi-mi:F8(display_short)|uniprotkb:F8C(gene name synonym)	psi-mi:fa8_human(display_long)|uniprotkb:Procoagulant component(gene name synonym)|uniprotkb:Antihemophilic factor(gene name synonym)|uniprotkb:F8(gene name)|psi-mi:F8(display_short)|uniprotkb:F8C(gene name synonym)	psi-mi:"MI:0114"(x-ray crystallography)	Ngo et al. (2008)	pubmed:18400180|doi:10.1016/j.str.2008.03.001|imex:IM-9161	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15697368|imex:IM-9161-1|dip:DIP-59261E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000185010(gene)|ensembl:ENST00000360256(transcript)|go:"GO:0005507"(copper ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005796"(Golgi lumen)|go:"GO:0005886"(plasma membrane)|go:"GO:0006953"(acute-phase response)|go:"GO:0007596"(blood coagulation)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0031093"(platelet alpha granule lumen)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|interpro:IPR000421(Coagulation factor 5/8 type, C-terminal)|interpro:IPR001117(Multicopper oxidase, type 1)|interpro:IPR008972(Cupredoxin)|interpro:IPR008979(Galactose-binding like)|interpro:IPR011706(Multicopper oxidase, type 2)|interpro:IPR011707(Multicopper oxidase, type 3)|interpro:IPR024715|interpro:IPR033138|rcsb pdb:1CFG|rcsb pdb:1D7P|rcsb pdb:1FAC|rcsb pdb:1IQD|rcsb pdb:2R7E|rcsb pdb:3CDZ|rcsb pdb:3HNB|rcsb pdb:3HNY|rcsb pdb:3HOB|rcsb pdb:3J2Q|rcsb pdb:3J2S|go:"GO:0007597"(blood coagulation, intrinsic pathway)|rcsb pdb:4BDV|rcsb pdb:4KI5|rcsb pdb:4PT6|rcsb pdb:4XZU|go:"GO:0016491"(oxidoreductase activity)|rcsb pdb:5K8D|rcsb pdb:6MF2|rcsb pdb:7KWO|reactome:R-HSA-114608|reactome:R-HSA-140837|reactome:R-HSA-140875|reactome:R-HSA-163841|reactome:R-HSA-204005|reactome:R-HSA-5694530|reactome:R-HSA-9672383|reactome:R-HSA-9672387|reactome:R-HSA-9672391|reactome:R-HSA-9672393|reactome:R-HSA-9672395|reactome:R-HSA-9672396|reactome:R-HSA-9672397|reactome:R-HSA-9673202|reactome:R-HSA-9674519|refseq:NP_000123.1|refseq:NP_063916.1|dip:DIP-29774N	ensembl:ENSG00000185010(gene)|ensembl:ENST00000360256(transcript)|go:"GO:0005507"(copper ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005796"(Golgi lumen)|go:"GO:0005886"(plasma membrane)|go:"GO:0006953"(acute-phase response)|go:"GO:0007596"(blood coagulation)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0031093"(platelet alpha granule lumen)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|interpro:IPR000421(Coagulation factor 5/8 type, C-terminal)|interpro:IPR001117(Multicopper oxidase, type 1)|interpro:IPR008972(Cupredoxin)|interpro:IPR008979(Galactose-binding like)|interpro:IPR011706(Multicopper oxidase, type 2)|interpro:IPR011707(Multicopper oxidase, type 3)|interpro:IPR024715|interpro:IPR033138|rcsb pdb:1CFG|rcsb pdb:1D7P|rcsb pdb:1FAC|rcsb pdb:1IQD|rcsb pdb:2R7E|rcsb pdb:3CDZ|rcsb pdb:3HNB|rcsb pdb:3HNY|rcsb pdb:3HOB|rcsb pdb:3J2Q|rcsb pdb:3J2S|go:"GO:0007597"(blood coagulation, intrinsic pathway)|rcsb pdb:4BDV|rcsb pdb:4KI5|rcsb pdb:4PT6|rcsb pdb:4XZU|go:"GO:0016491"(oxidoreductase activity)|rcsb pdb:5K8D|rcsb pdb:6MF2|rcsb pdb:7KWO|reactome:R-HSA-114608|reactome:R-HSA-140837|reactome:R-HSA-140875|reactome:R-HSA-163841|reactome:R-HSA-204005|reactome:R-HSA-5694530|reactome:R-HSA-9672383|reactome:R-HSA-9672387|reactome:R-HSA-9672391|reactome:R-HSA-9672393|reactome:R-HSA-9672395|reactome:R-HSA-9672396|reactome:R-HSA-9672397|reactome:R-HSA-9673202|reactome:R-HSA-9674519|refseq:NP_000123.1|refseq:NP_063916.1|dip:DIP-29774N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10029(crigr)|taxid:10029("Cricetulus griseus (Chinese hamster)")	-	2017/08/05	2017/08/10	rogid:yKYkVF2eCO1fS/Dp3/k1qcP5YM49606	rogid:yKYkVF2eCO1fS/Dp3/k1qcP5YM49606	rigid:8ZoYDiMaG87U6UGr5YaZZ0W+oi8	false	binding-associated region:20-764|binding-associated region:1668-2351	binding-associated region:20-764|binding-associated region:1668-2351	-	0	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)