#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:A0EZR6 uniprotkb:Q93105 intact:EBI-15696775 intact:EBI-15696740|uniprotkb:Q17IL5 psi-mi:a0ezr6_aedae(display_long) psi-mi:insr_aedae(display_long)|uniprotkb:InR(gene name)|psi-mi:InR(display_short)|uniprotkb:AAEL002317(orf name) psi-mi:"MI:0030"(cross-linking study) Brown et al. (2008) pubmed:18391205|doi:10.1073/pnas.0800478105|imex:IM-9223 taxid:7159(aedae)|taxid:7159("Aedes aegypti (Yellowfever mosquito)") taxid:7159(aedae)|taxid:7159("Aedes aegypti (Yellowfever mosquito)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15696785|imex:IM-9223-1|dip:DIP-59404E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005179"(hormone activity)|go:"GO:0005576"(extracellular region)|interpro:IPR016179(Insulin-like)|interpro:IPR022352|interpro:IPR022353|interpro:IPR036438|interpro:IPR040228|dip:DIP-29909N go:"GO:0005009"(insulin-activated receptor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0043559"(insulin binding)|go:"GO:0043560"(insulin receptor substrate binding)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|interpro:IPR000494(EGF receptor, L domain)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR002011(Receptor tyrosine kinase, class II, conserved site)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR006211(Furin-like cysteine rich region)|interpro:IPR006212(Furin-like repeat)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR016246(Insulin receptor)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR036116|interpro:IPR036941|refseq:XP_001661260.1|dip:DIP-29908N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/05 2017/08/10 rogid:jVIseM5aqr8WtpaWSjXdOVm7P007159 rogid:GlMTSRpOAJxiHZ08/xDWKIxQQEU7159 rigid:ijRedb3vKvNObW6xDnJlGlshKVY false - - - - psi-mi:"MI:0821"(molecular weight estimation by autoradiography) psi-mi:"MI:0821"(molecular weight estimation by autoradiography)