#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:O96433	uniprotkb:Q15545	intact:EBI-191577|uniprotkb:Q9VVI6|ensemblmetazoa:FBpp0074968|ensemblmetazoa:FBpp0305335	intact:EBI-1560194|uniprotkb:Q13036|uniprotkb:B2RBV9|ensembl:ENSP00000312709	psi-mi:ccnt_drome(display_long)|uniprotkb:CycT(gene name)|psi-mi:CycT(display_short)|uniprotkb:CG6292(orf name)	psi-mi:taf7_human(display_long)|uniprotkb:Transcription initiation factor TFIID 55 kDa subunit(gene name synonym)|uniprotkb:RNA polymerase II TBP-associated factor subunit F(gene name synonym)|uniprotkb:TAF7(gene name)|psi-mi:TAF7(display_short)|uniprotkb:TAF2F(gene name synonym)|uniprotkb:TAFII55(gene name synonym)	psi-mi:"MI:0096"(pull down)	Gegonne et al. (2008)	pubmed:18391197|doi:10.1073/pnas.0801637105|imex:IM-9215	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15696472|imex:IM-9215-1|dip:DIP-59387E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_524127.2|refseq:NP_996117.1|flybase:FBgn0025455|refseq:NP_001261992.1|refseq:NP_001261993.1|dip:DIP-29892N|ensemblmetazoa:FBgn0025455(gene)|ensemblmetazoa:FBtr0075205(transcript)|ensemblmetazoa:FBtr0333124(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005700"(polytene chromosome)|go:"GO:0005703"(polytene chromosome puff)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007419"(ventral cord development)|go:"GO:0008023"(transcription elongation factor complex)|go:"GO:0008024"(cyclin/CDK positive transcription elongation factor complex)|go:"GO:0009408"(response to heat)|go:"GO:0016538"(cyclin-dependent protein serine/threonine kinase regulator activity)|go:"GO:0032783"(super elongation complex)|go:"GO:0032786"(positive regulation of DNA-templated transcription, elongation)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0061575"(cyclin-dependent protein serine/threonine kinase activator activity)|go:"GO:0070691"(P-TEFb complex)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|interpro:IPR006671(Cyclin, N-terminal)|interpro:IPR013763(Cyclin-related)|interpro:IPR028863|interpro:IPR036915|interpro:IPR043198|reactome:R-DME-112382|reactome:R-DME-2173796|reactome:R-DME-674695|reactome:R-DME-6796648|reactome:R-DME-6807505|reactome:R-DME-75955|reactome:R-DME-9018519	refseq:NP_005633.2|dip:DIP-29047N|ensembl:ENSG00000178913(gene)|ensembl:ENST00000313368(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000296"(spermine transport)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001097"(TFIIH-class transcription factor complex binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006352"(DNA-templated transcription, initiation)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016251"(RNA polymerase II general transcription initiation factor activity)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0033276"(transcription factor TFTC complex)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0035067"(negative regulation of histone acetylation)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0045344"(negative regulation of MHC class I biosynthetic process)|go:"GO:0045347"(negative regulation of MHC class II biosynthetic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051123"(RNA polymerase II preinitiation complex assembly)|go:"GO:0071339"(MLL1 complex)|go:"GO:0090241"(negative regulation of histone H4 acetylation)|go:"GO:0106140"(P-TEFb complex binding)|interpro:IPR006751(TAFII55 protein conserved region)|interpro:IPR037817|rcsb pdb:4RGW|rcsb pdb:5FUR|rcsb pdb:6MZL|rcsb pdb:6MZM|rcsb pdb:7EDX|rcsb pdb:7EG7|rcsb pdb:7EG8|rcsb pdb:7EG9|rcsb pdb:7EGA|rcsb pdb:7EGB|rcsb pdb:7EGC|rcsb pdb:7EGD|rcsb pdb:7EGE|rcsb pdb:7EGH|rcsb pdb:7EGI|rcsb pdb:7EGJ|rcsb pdb:7ENA|rcsb pdb:7ENC|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-674695|reactome:R-HSA-6804756|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-75953|reactome:R-HSA-76042	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/05	2017/08/10	rogid:ETtMNDDCR0XQyrwPvavX7lDPdaA7227	rogid:FFk04k421YC/B0n/5GXpDK9uhBU9606	rigid:UlJy9MJV8nR53SytM/r3UoFalj8	false	-	necessary binding region:204-349|flag tag:n-n	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P21675	uniprotkb:Q15545	intact:EBI-491289|uniprotkb:A5CVD0|uniprotkb:Q6IUZ1|uniprotkb:Q70Q86|uniprotkb:Q70Q87|uniprotkb:Q70T00|uniprotkb:Q70T01|uniprotkb:Q70T02|uniprotkb:Q70T03|uniprotkb:Q59FZ3|ensembl:ENSP00000276072|ensembl:ENSP00000362895|ensembl:ENSP00000406549|uniprotkb:A5CVC8|uniprotkb:A5CVC9|uniprotkb:A5CVD1|uniprotkb:B1Q2X3	intact:EBI-1560194|uniprotkb:Q13036|uniprotkb:B2RBV9|ensembl:ENSP00000312709	psi-mi:taf1_human(display_long)|uniprotkb:TAF1(gene name)|psi-mi:TAF1(display_short)|uniprotkb:BA2R(gene name synonym)|uniprotkb:CCG1(gene name synonym)|uniprotkb:TAF2A(gene name synonym)|uniprotkb:CCGS(gene name synonym)|uniprotkb:Transcription initiation factor TFIID 250 kDa subunit(gene name synonym)|uniprotkb:TBP-associated factor 250 kDa(gene name synonym)|uniprotkb:Cell cycle gene 1 protein(gene name synonym)	psi-mi:taf7_human(display_long)|uniprotkb:Transcription initiation factor TFIID 55 kDa subunit(gene name synonym)|uniprotkb:RNA polymerase II TBP-associated factor subunit F(gene name synonym)|uniprotkb:TAF7(gene name)|psi-mi:TAF7(display_short)|uniprotkb:TAF2F(gene name synonym)|uniprotkb:TAFII55(gene name synonym)	psi-mi:"MI:0071"(molecular sieving)	Gegonne et al. (2008)	pubmed:18391197|doi:10.1073/pnas.0801637105|imex:IM-9215	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15696493|dip:DIP-59389E|imex:IM-9215-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001273003.1|rcsb pdb:6MZM|refseq:NP_004597.2|refseq:NP_620278.1|rcsb pdb:6P38|rcsb pdb:6P39|rcsb pdb:6P3A|rcsb pdb:7EDX|rcsb pdb:7EG7|rcsb pdb:7EG8|rcsb pdb:7EG9|rcsb pdb:7EGA|rcsb pdb:7EGB|rcsb pdb:7EGC|rcsb pdb:7EGD|rcsb pdb:7EGE|rcsb pdb:7EGH|rcsb pdb:7EGI|rcsb pdb:7EGJ|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7JJH|rcsb pdb:7L6X|rcsb pdb:7N42|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-674695|reactome:R-HSA-6804756|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-75953|reactome:R-HSA-76042|reactome:R-HSA-167172|ensembl:ENSG00000147133(gene)|ensembl:ENST00000276072(transcript)|ensembl:ENST00000373790(transcript)|ensembl:ENST00000423759(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000785"(chromatin)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0001181"(RNA polymerase I general transcription initiation factor activity)|go:"GO:0002039"(p53 binding)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0006361"(transcription initiation from RNA polymerase I promoter)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0030901"(midbrain development)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0034644"(cellular response to UV)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0036369"(transcription factor catabolic process)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007049"(cell cycle)|go:"GO:0008134"(transcription factor binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016251"(RNA polymerase II general transcription initiation factor activity)|go:"GO:0050821"(protein stabilization)|go:"GO:0051123"(RNA polymerase II preinitiation complex assembly)|go:"GO:0016301"(kinase activity)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070577"(lysine-acetylated histone binding)|go:"GO:0071318"(cellular response to ATP)|go:"GO:0071339"(MLL1 complex)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:0140416"(transcription regulator inhibitor activity)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|go:"GO:1902806"(regulation of cell cycle G1/S phase transition)|go:"GO:1903026"(negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding)|go:"GO:1905524"(negative regulation of protein autoubiquitination)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:2000825"(positive regulation of androgen receptor activity)|interpro:IPR001487(Bromodomain)|interpro:IPR009067(TAFII-230 TBP-binding)|interpro:IPR011177(Transcription initiation factor TFIID subunit 1, animal)|interpro:IPR018359|interpro:IPR022591|interpro:IPR036427|interpro:IPR036741|interpro:IPR040240|interpro:IPR041670|mint:P21675|rcsb pdb:1EQF|rcsb pdb:3AAD|rcsb pdb:3UV4|rcsb pdb:3UV5|rcsb pdb:4RGW|rcsb pdb:4YYM|rcsb pdb:4YYN|rcsb pdb:5FUR|rcsb pdb:5I1Q|rcsb pdb:5I29|rcsb pdb:5MG2|rcsb pdb:6BQD|rcsb pdb:6FIC|rcsb pdb:6MZD|rcsb pdb:6MZL|refseq:XP_005262354.1|dip:DIP-147N	refseq:NP_005633.2|dip:DIP-29047N|ensembl:ENSG00000178913(gene)|ensembl:ENST00000313368(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000296"(spermine transport)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001097"(TFIIH-class transcription factor complex binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006352"(DNA-templated transcription, initiation)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016251"(RNA polymerase II general transcription initiation factor activity)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0033276"(transcription factor TFTC complex)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0035067"(negative regulation of histone acetylation)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0045344"(negative regulation of MHC class I biosynthetic process)|go:"GO:0045347"(negative regulation of MHC class II biosynthetic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051123"(RNA polymerase II preinitiation complex assembly)|go:"GO:0071339"(MLL1 complex)|go:"GO:0090241"(negative regulation of histone H4 acetylation)|go:"GO:0106140"(P-TEFb complex binding)|interpro:IPR006751(TAFII55 protein conserved region)|interpro:IPR037817|rcsb pdb:4RGW|rcsb pdb:5FUR|rcsb pdb:6MZL|rcsb pdb:6MZM|rcsb pdb:7EDX|rcsb pdb:7EG7|rcsb pdb:7EG8|rcsb pdb:7EG9|rcsb pdb:7EGA|rcsb pdb:7EGB|rcsb pdb:7EGC|rcsb pdb:7EGD|rcsb pdb:7EGE|rcsb pdb:7EGH|rcsb pdb:7EGI|rcsb pdb:7EGJ|rcsb pdb:7ENA|rcsb pdb:7ENC|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-674695|reactome:R-HSA-6804756|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-75953|reactome:R-HSA-76042	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2017/08/05	2017/08/10	rogid:P0LoULOvon+Wp2G17lBlqn3Fo4E9606	rogid:FFk04k421YC/B0n/5GXpDK9uhBU9606	rigid:oB03irp3cwUOoi8139PtEdr719Y	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P21675	uniprotkb:P20226	intact:EBI-491289|uniprotkb:A5CVD0|uniprotkb:Q6IUZ1|uniprotkb:Q70Q86|uniprotkb:Q70Q87|uniprotkb:Q70T00|uniprotkb:Q70T01|uniprotkb:Q70T02|uniprotkb:Q70T03|uniprotkb:Q59FZ3|ensembl:ENSP00000276072|ensembl:ENSP00000362895|ensembl:ENSP00000406549|uniprotkb:A5CVC8|uniprotkb:A5CVC9|uniprotkb:A5CVD1|uniprotkb:B1Q2X3	intact:EBI-355371|uniprotkb:Q16845|uniprotkb:Q9UC02|intact:EBI-1056192|uniprotkb:Q6IBM6|ensembl:ENSP00000230354|ensembl:ENSP00000375942|intact:EBI-11019728|uniprotkb:B4E3B3|uniprotkb:F5H869	psi-mi:taf1_human(display_long)|uniprotkb:TAF1(gene name)|psi-mi:TAF1(display_short)|uniprotkb:BA2R(gene name synonym)|uniprotkb:CCG1(gene name synonym)|uniprotkb:TAF2A(gene name synonym)|uniprotkb:CCGS(gene name synonym)|uniprotkb:Transcription initiation factor TFIID 250 kDa subunit(gene name synonym)|uniprotkb:TBP-associated factor 250 kDa(gene name synonym)|uniprotkb:Cell cycle gene 1 protein(gene name synonym)	psi-mi:tbp_human(display_long)|uniprotkb:TBP(gene name)|psi-mi:TBP(display_short)|uniprotkb:TF2D(gene name synonym)|uniprotkb:TFIID(gene name synonym)|uniprotkb:GTF2D1(gene name synonym)|uniprotkb:TATA-box factor(gene name synonym)|uniprotkb:TATA-binding factor(gene name synonym)|uniprotkb:TATA sequence-binding protein(gene name synonym)|uniprotkb:Transcription initiation factor TFIID TBP subunit(gene name synonym)	psi-mi:"MI:0071"(molecular sieving)	Gegonne et al. (2008)	pubmed:18391197|doi:10.1073/pnas.0801637105|imex:IM-9215	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15696493|dip:DIP-59389E|imex:IM-9215-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001273003.1|rcsb pdb:6MZM|refseq:NP_004597.2|refseq:NP_620278.1|rcsb pdb:6P38|rcsb pdb:6P39|rcsb pdb:6P3A|rcsb pdb:7EDX|rcsb pdb:7EG7|rcsb pdb:7EG8|rcsb pdb:7EG9|rcsb pdb:7EGA|rcsb pdb:7EGB|rcsb pdb:7EGC|rcsb pdb:7EGD|rcsb pdb:7EGE|rcsb pdb:7EGH|rcsb pdb:7EGI|rcsb pdb:7EGJ|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7JJH|rcsb pdb:7L6X|rcsb pdb:7N42|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-674695|reactome:R-HSA-6804756|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-75953|reactome:R-HSA-76042|reactome:R-HSA-167172|ensembl:ENSG00000147133(gene)|ensembl:ENST00000276072(transcript)|ensembl:ENST00000373790(transcript)|ensembl:ENST00000423759(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000785"(chromatin)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0001181"(RNA polymerase I general transcription initiation factor activity)|go:"GO:0002039"(p53 binding)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0006361"(transcription initiation from RNA polymerase I promoter)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0030901"(midbrain development)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0034644"(cellular response to UV)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0036369"(transcription factor catabolic process)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007049"(cell cycle)|go:"GO:0008134"(transcription factor binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016251"(RNA polymerase II general transcription initiation factor activity)|go:"GO:0050821"(protein stabilization)|go:"GO:0051123"(RNA polymerase II preinitiation complex assembly)|go:"GO:0016301"(kinase activity)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070577"(lysine-acetylated histone binding)|go:"GO:0071318"(cellular response to ATP)|go:"GO:0071339"(MLL1 complex)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:0140416"(transcription regulator inhibitor activity)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|go:"GO:1902806"(regulation of cell cycle G1/S phase transition)|go:"GO:1903026"(negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding)|go:"GO:1905524"(negative regulation of protein autoubiquitination)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:2000825"(positive regulation of androgen receptor activity)|interpro:IPR001487(Bromodomain)|interpro:IPR009067(TAFII-230 TBP-binding)|interpro:IPR011177(Transcription initiation factor TFIID subunit 1, animal)|interpro:IPR018359|interpro:IPR022591|interpro:IPR036427|interpro:IPR036741|interpro:IPR040240|interpro:IPR041670|mint:P21675|rcsb pdb:1EQF|rcsb pdb:3AAD|rcsb pdb:3UV4|rcsb pdb:3UV5|rcsb pdb:4RGW|rcsb pdb:4YYM|rcsb pdb:4YYN|rcsb pdb:5FUR|rcsb pdb:5I1Q|rcsb pdb:5I29|rcsb pdb:5MG2|rcsb pdb:6BQD|rcsb pdb:6FIC|rcsb pdb:6MZD|rcsb pdb:6MZL|refseq:XP_005262354.1|dip:DIP-147N	refseq:NP_001165556.1|refseq:NP_003185.1|ensembl:ENSP00000230354|ensembl:ENSP00000375942|ensembl:ENST00000540980|ensembl:ENSP00000442132|ensembl:ENSG00000112592(gene)|ensembl:ENST00000230354(transcript)|ensembl:ENST00000392092(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000791"(euchromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0000995"(RNA polymerase III general transcription initiation factor activity)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0001091"(RNA polymerase II general transcription initiation factor binding)|go:"GO:0001093"(TFIIB-class transcription factor binding)|go:"GO:0001939"(female pronucleus)|go:"GO:0001940"(male pronucleus)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0005672"(transcription factor TFIIA complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006352"(DNA-templated transcription, initiation)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006383"(transcription by RNA polymerase III)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016251"(RNA polymerase II general transcription initiation factor activity)|go:"GO:0017162"(aryl hydrocarbon receptor binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051123"(RNA polymerase II preinitiation complex assembly)|go:"GO:0097550"(transcription preinitiation complex)|go:"GO:0140223"(general transcription initiation factor activity)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR000814(TATA-box binding)|interpro:IPR012295(Beta2-adaptin/TATA-box binding, C-terminal)|interpro:IPR030491|interpro:IPR033710|mint:P20226|rcsb pdb:1C9B|rcsb pdb:1CDW|rcsb pdb:1JFI|rcsb pdb:1NVP|rcsb pdb:1TGH|rcsb pdb:4ROC|rcsb pdb:4ROD|rcsb pdb:4ROE|rcsb pdb:5FUR|rcsb pdb:5IY6|rcsb pdb:5IY7|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5IYA|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|rcsb pdb:5N9G|rcsb pdb:6MZD|rcsb pdb:6MZL|rcsb pdb:6MZM|rcsb pdb:6O9L|rcsb pdb:7EDX|rcsb pdb:7EG7|rcsb pdb:7EG8|rcsb pdb:7EG9|rcsb pdb:7EGA|rcsb pdb:7EGB|rcsb pdb:7EGC|rcsb pdb:7EGD|rcsb pdb:7EGE|rcsb pdb:7EGF|rcsb pdb:7EGI|rcsb pdb:7EGJ|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7LBM|rcsb pdb:7NVR|rcsb pdb:7NVS|rcsb pdb:7NVT|rcsb pdb:7NVU|rcsb pdb:7NVY|rcsb pdb:7NVZ|rcsb pdb:7NW0|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-427359|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-674695|reactome:R-HSA-6804756|reactome:R-HSA-6807505|reactome:R-HSA-73762|reactome:R-HSA-73772|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-73863|reactome:R-HSA-749476|reactome:R-HSA-75953|reactome:R-HSA-76042|reactome:R-HSA-76061|reactome:R-HSA-76066|reactome:R-HSA-76071|reactome:R-HSA-9018519|dip:DIP-1078N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2017/08/05	2017/08/10	rogid:P0LoULOvon+Wp2G17lBlqn3Fo4E9606	rogid:tH4ckPOwO4Icr1YsnJ1Ck/6Cgmo9606	rigid:oB03irp3cwUOoi8139PtEdr719Y	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q15545	uniprotkb:O60563	intact:EBI-1560194|uniprotkb:Q13036|uniprotkb:B2RBV9|ensembl:ENSP00000312709	intact:EBI-2479671|ensembl:ENSP00000261900|uniprotkb:O60581|uniprotkb:A9XU13|uniprotkb:E7EX76	psi-mi:taf7_human(display_long)|uniprotkb:Transcription initiation factor TFIID 55 kDa subunit(gene name synonym)|uniprotkb:RNA polymerase II TBP-associated factor subunit F(gene name synonym)|uniprotkb:TAF7(gene name)|psi-mi:TAF7(display_short)|uniprotkb:TAF2F(gene name synonym)|uniprotkb:TAFII55(gene name synonym)	psi-mi:ccnt1_human(display_long)|uniprotkb:CCNT1(gene name)|psi-mi:CCNT1(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Gegonne et al. (2008)	pubmed:18391197|doi:10.1073/pnas.0801637105|imex:IM-9215	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15696511|imex:IM-9215-3|dip:DIP-59388E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005633.2|dip:DIP-29047N|ensembl:ENSG00000178913(gene)|ensembl:ENST00000313368(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000296"(spermine transport)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001097"(TFIIH-class transcription factor complex binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006352"(DNA-templated transcription, initiation)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016251"(RNA polymerase II general transcription initiation factor activity)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0033276"(transcription factor TFTC complex)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0035067"(negative regulation of histone acetylation)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0045344"(negative regulation of MHC class I biosynthetic process)|go:"GO:0045347"(negative regulation of MHC class II biosynthetic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051123"(RNA polymerase II preinitiation complex assembly)|go:"GO:0071339"(MLL1 complex)|go:"GO:0090241"(negative regulation of histone H4 acetylation)|go:"GO:0106140"(P-TEFb complex binding)|interpro:IPR006751(TAFII55 protein conserved region)|interpro:IPR037817|rcsb pdb:4RGW|rcsb pdb:5FUR|rcsb pdb:6MZL|rcsb pdb:6MZM|rcsb pdb:7EDX|rcsb pdb:7EG7|rcsb pdb:7EG8|rcsb pdb:7EG9|rcsb pdb:7EGA|rcsb pdb:7EGB|rcsb pdb:7EGC|rcsb pdb:7EGD|rcsb pdb:7EGE|rcsb pdb:7EGH|rcsb pdb:7EGI|rcsb pdb:7EGJ|rcsb pdb:7ENA|rcsb pdb:7ENC|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-674695|reactome:R-HSA-6804756|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-75953|reactome:R-HSA-76042	go:"GO:0097322"(7SK snRNA binding)|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|interpro:IPR006671(Cyclin, N-terminal)|go:"GO:0070691"(P-TEFb complex)|interpro:IPR013763(Cyclin-related)|interpro:IPR028863|interpro:IPR036915|interpro:IPR043198|mint:O60563|rcsb pdb:2PK2|rcsb pdb:3BLH|rcsb pdb:3BLQ|rcsb pdb:3BLR|rcsb pdb:3LQ5|rcsb pdb:3MI9|rcsb pdb:3MIA|rcsb pdb:3MY1|rcsb pdb:3TN8|rcsb pdb:3TNH|rcsb pdb:3TNI|rcsb pdb:4BCF|rcsb pdb:4BCG|rcsb pdb:4BCH|rcsb pdb:4BCI|rcsb pdb:4BCJ|rcsb pdb:4EC8|rcsb pdb:4EC9|rcsb pdb:4IMY|rcsb pdb:4OGR|rcsb pdb:4OR5|rcsb pdb:5L1Z|rcsb pdb:6CYT|rcsb pdb:6GZH|rcsb pdb:6Z45|reactome:R-HSA-112382|reactome:R-HSA-167152|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-176034|reactome:R-HSA-2173796|reactome:R-HSA-674695|reactome:R-HSA-6796648|reactome:R-HSA-6807505|reactome:R-HSA-75955|reactome:R-HSA-9018519|ensembl:ENSG00000129315(gene)|ensembl:ENST00000261900(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0008024"(cyclin/CDK positive transcription elongation factor complex)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016538"(cyclin-dependent protein serine/threonine kinase regulator activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032786"(positive regulation of DNA-templated transcription, elongation)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051301"(cell division)|go:"GO:0061575"(cyclin-dependent protein serine/threonine kinase activator activity)|go:"GO:0070063"(RNA polymerase binding)|refseq:NP_001231.2|refseq:NP_001264771.1|dip:DIP-29891N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2017/08/05	2017/08/10	rogid:FFk04k421YC/B0n/5GXpDK9uhBU9606	rogid:y80GILqwBbb5hMtl/4U1Y/vNx909606	rigid:rUvIDwsBAFvZS/+6ssaRSjQhEl4	false	flag tag:n-n	-	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:P21675	uniprotkb:Q15545	intact:EBI-491289|uniprotkb:A5CVD0|uniprotkb:Q6IUZ1|uniprotkb:Q70Q86|uniprotkb:Q70Q87|uniprotkb:Q70T00|uniprotkb:Q70T01|uniprotkb:Q70T02|uniprotkb:Q70T03|uniprotkb:Q59FZ3|ensembl:ENSP00000276072|ensembl:ENSP00000362895|ensembl:ENSP00000406549|uniprotkb:A5CVC8|uniprotkb:A5CVC9|uniprotkb:A5CVD1|uniprotkb:B1Q2X3	intact:EBI-1560194|uniprotkb:Q13036|uniprotkb:B2RBV9|ensembl:ENSP00000312709	psi-mi:taf1_human(display_long)|uniprotkb:TAF1(gene name)|psi-mi:TAF1(display_short)|uniprotkb:BA2R(gene name synonym)|uniprotkb:CCG1(gene name synonym)|uniprotkb:TAF2A(gene name synonym)|uniprotkb:CCGS(gene name synonym)|uniprotkb:Transcription initiation factor TFIID 250 kDa subunit(gene name synonym)|uniprotkb:TBP-associated factor 250 kDa(gene name synonym)|uniprotkb:Cell cycle gene 1 protein(gene name synonym)	psi-mi:taf7_human(display_long)|uniprotkb:Transcription initiation factor TFIID 55 kDa subunit(gene name synonym)|uniprotkb:RNA polymerase II TBP-associated factor subunit F(gene name synonym)|uniprotkb:TAF7(gene name)|psi-mi:TAF7(display_short)|uniprotkb:TAF2F(gene name synonym)|uniprotkb:TAFII55(gene name synonym)	psi-mi:"MI:0071"(molecular sieving)	Gegonne et al. (2008)	pubmed:18391197|doi:10.1073/pnas.0801637105|imex:IM-9215	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15696530|dip:DIP-192533E|imex:IM-9215-6	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001273003.1|rcsb pdb:6MZM|refseq:NP_004597.2|refseq:NP_620278.1|rcsb pdb:6P38|rcsb pdb:6P39|rcsb pdb:6P3A|rcsb pdb:7EDX|rcsb pdb:7EG7|rcsb pdb:7EG8|rcsb pdb:7EG9|rcsb pdb:7EGA|rcsb pdb:7EGB|rcsb pdb:7EGC|rcsb pdb:7EGD|rcsb pdb:7EGE|rcsb pdb:7EGH|rcsb pdb:7EGI|rcsb pdb:7EGJ|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7JJH|rcsb pdb:7L6X|rcsb pdb:7N42|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-674695|reactome:R-HSA-6804756|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-75953|reactome:R-HSA-76042|reactome:R-HSA-167172|ensembl:ENSG00000147133(gene)|ensembl:ENST00000276072(transcript)|ensembl:ENST00000373790(transcript)|ensembl:ENST00000423759(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000785"(chromatin)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0001181"(RNA polymerase I general transcription initiation factor activity)|go:"GO:0002039"(p53 binding)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0006361"(transcription initiation from RNA polymerase I promoter)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0030901"(midbrain development)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0034644"(cellular response to UV)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0036369"(transcription factor catabolic process)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007049"(cell cycle)|go:"GO:0008134"(transcription factor binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016251"(RNA polymerase II general transcription initiation factor activity)|go:"GO:0050821"(protein stabilization)|go:"GO:0051123"(RNA polymerase II preinitiation complex assembly)|go:"GO:0016301"(kinase activity)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070577"(lysine-acetylated histone binding)|go:"GO:0071318"(cellular response to ATP)|go:"GO:0071339"(MLL1 complex)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:0140416"(transcription regulator inhibitor activity)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|go:"GO:1902806"(regulation of cell cycle G1/S phase transition)|go:"GO:1903026"(negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding)|go:"GO:1905524"(negative regulation of protein autoubiquitination)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:2000825"(positive regulation of androgen receptor activity)|interpro:IPR001487(Bromodomain)|interpro:IPR009067(TAFII-230 TBP-binding)|interpro:IPR011177(Transcription initiation factor TFIID subunit 1, animal)|interpro:IPR018359|interpro:IPR022591|interpro:IPR036427|interpro:IPR036741|interpro:IPR040240|interpro:IPR041670|mint:P21675|rcsb pdb:1EQF|rcsb pdb:3AAD|rcsb pdb:3UV4|rcsb pdb:3UV5|rcsb pdb:4RGW|rcsb pdb:4YYM|rcsb pdb:4YYN|rcsb pdb:5FUR|rcsb pdb:5I1Q|rcsb pdb:5I29|rcsb pdb:5MG2|rcsb pdb:6BQD|rcsb pdb:6FIC|rcsb pdb:6MZD|rcsb pdb:6MZL|refseq:XP_005262354.1|dip:DIP-147N	refseq:NP_005633.2|dip:DIP-29047N|ensembl:ENSG00000178913(gene)|ensembl:ENST00000313368(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000296"(spermine transport)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001097"(TFIIH-class transcription factor complex binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006352"(DNA-templated transcription, initiation)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016251"(RNA polymerase II general transcription initiation factor activity)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0033276"(transcription factor TFTC complex)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0035067"(negative regulation of histone acetylation)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0045344"(negative regulation of MHC class I biosynthetic process)|go:"GO:0045347"(negative regulation of MHC class II biosynthetic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051123"(RNA polymerase II preinitiation complex assembly)|go:"GO:0071339"(MLL1 complex)|go:"GO:0090241"(negative regulation of histone H4 acetylation)|go:"GO:0106140"(P-TEFb complex binding)|interpro:IPR006751(TAFII55 protein conserved region)|interpro:IPR037817|rcsb pdb:4RGW|rcsb pdb:5FUR|rcsb pdb:6MZL|rcsb pdb:6MZM|rcsb pdb:7EDX|rcsb pdb:7EG7|rcsb pdb:7EG8|rcsb pdb:7EG9|rcsb pdb:7EGA|rcsb pdb:7EGB|rcsb pdb:7EGC|rcsb pdb:7EGD|rcsb pdb:7EGE|rcsb pdb:7EGH|rcsb pdb:7EGI|rcsb pdb:7EGJ|rcsb pdb:7ENA|rcsb pdb:7ENC|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-674695|reactome:R-HSA-6804756|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-75953|reactome:R-HSA-76042	psi-mi:"MI:0465"(dip)	-	-	dip-version:1|dip-updated-by:nodeMerge04|dip-date-update:2013-12-24|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2017/08/05	2017/08/10	rogid:P0LoULOvon+Wp2G17lBlqn3Fo4E9606	rogid:FFk04k421YC/B0n/5GXpDK9uhBU9606	rigid:oB03irp3cwUOoi8139PtEdr719Y	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P21675	uniprotkb:P20226	intact:EBI-491289|uniprotkb:A5CVD0|uniprotkb:Q6IUZ1|uniprotkb:Q70Q86|uniprotkb:Q70Q87|uniprotkb:Q70T00|uniprotkb:Q70T01|uniprotkb:Q70T02|uniprotkb:Q70T03|uniprotkb:Q59FZ3|ensembl:ENSP00000276072|ensembl:ENSP00000362895|ensembl:ENSP00000406549|uniprotkb:A5CVC8|uniprotkb:A5CVC9|uniprotkb:A5CVD1|uniprotkb:B1Q2X3	intact:EBI-355371|uniprotkb:Q16845|uniprotkb:Q9UC02|intact:EBI-1056192|uniprotkb:Q6IBM6|ensembl:ENSP00000230354|ensembl:ENSP00000375942|intact:EBI-11019728|uniprotkb:B4E3B3|uniprotkb:F5H869	psi-mi:taf1_human(display_long)|uniprotkb:TAF1(gene name)|psi-mi:TAF1(display_short)|uniprotkb:BA2R(gene name synonym)|uniprotkb:CCG1(gene name synonym)|uniprotkb:TAF2A(gene name synonym)|uniprotkb:CCGS(gene name synonym)|uniprotkb:Transcription initiation factor TFIID 250 kDa subunit(gene name synonym)|uniprotkb:TBP-associated factor 250 kDa(gene name synonym)|uniprotkb:Cell cycle gene 1 protein(gene name synonym)	psi-mi:tbp_human(display_long)|uniprotkb:TBP(gene name)|psi-mi:TBP(display_short)|uniprotkb:TF2D(gene name synonym)|uniprotkb:TFIID(gene name synonym)|uniprotkb:GTF2D1(gene name synonym)|uniprotkb:TATA-box factor(gene name synonym)|uniprotkb:TATA-binding factor(gene name synonym)|uniprotkb:TATA sequence-binding protein(gene name synonym)|uniprotkb:Transcription initiation factor TFIID TBP subunit(gene name synonym)	psi-mi:"MI:0071"(molecular sieving)	Gegonne et al. (2008)	pubmed:18391197|doi:10.1073/pnas.0801637105|imex:IM-9215	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15696530|dip:DIP-192533E|imex:IM-9215-6	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001273003.1|rcsb pdb:6MZM|refseq:NP_004597.2|refseq:NP_620278.1|rcsb pdb:6P38|rcsb pdb:6P39|rcsb pdb:6P3A|rcsb pdb:7EDX|rcsb pdb:7EG7|rcsb pdb:7EG8|rcsb pdb:7EG9|rcsb pdb:7EGA|rcsb pdb:7EGB|rcsb pdb:7EGC|rcsb pdb:7EGD|rcsb pdb:7EGE|rcsb pdb:7EGH|rcsb pdb:7EGI|rcsb pdb:7EGJ|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7JJH|rcsb pdb:7L6X|rcsb pdb:7N42|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-674695|reactome:R-HSA-6804756|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-75953|reactome:R-HSA-76042|reactome:R-HSA-167172|ensembl:ENSG00000147133(gene)|ensembl:ENST00000276072(transcript)|ensembl:ENST00000373790(transcript)|ensembl:ENST00000423759(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000785"(chromatin)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0001181"(RNA polymerase I general transcription initiation factor activity)|go:"GO:0002039"(p53 binding)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0006361"(transcription initiation from RNA polymerase I promoter)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0030901"(midbrain development)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0034644"(cellular response to UV)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0036369"(transcription factor catabolic process)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007049"(cell cycle)|go:"GO:0008134"(transcription factor binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016251"(RNA polymerase II general transcription initiation factor activity)|go:"GO:0050821"(protein stabilization)|go:"GO:0051123"(RNA polymerase II preinitiation complex assembly)|go:"GO:0016301"(kinase activity)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070577"(lysine-acetylated histone binding)|go:"GO:0071318"(cellular response to ATP)|go:"GO:0071339"(MLL1 complex)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:0140416"(transcription regulator inhibitor activity)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|go:"GO:1902806"(regulation of cell cycle G1/S phase transition)|go:"GO:1903026"(negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding)|go:"GO:1905524"(negative regulation of protein autoubiquitination)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:2000825"(positive regulation of androgen receptor activity)|interpro:IPR001487(Bromodomain)|interpro:IPR009067(TAFII-230 TBP-binding)|interpro:IPR011177(Transcription initiation factor TFIID subunit 1, animal)|interpro:IPR018359|interpro:IPR022591|interpro:IPR036427|interpro:IPR036741|interpro:IPR040240|interpro:IPR041670|mint:P21675|rcsb pdb:1EQF|rcsb pdb:3AAD|rcsb pdb:3UV4|rcsb pdb:3UV5|rcsb pdb:4RGW|rcsb pdb:4YYM|rcsb pdb:4YYN|rcsb pdb:5FUR|rcsb pdb:5I1Q|rcsb pdb:5I29|rcsb pdb:5MG2|rcsb pdb:6BQD|rcsb pdb:6FIC|rcsb pdb:6MZD|rcsb pdb:6MZL|refseq:XP_005262354.1|dip:DIP-147N	refseq:NP_001165556.1|refseq:NP_003185.1|ensembl:ENSP00000230354|ensembl:ENSP00000375942|ensembl:ENST00000540980|ensembl:ENSP00000442132|ensembl:ENSG00000112592(gene)|ensembl:ENST00000230354(transcript)|ensembl:ENST00000392092(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000791"(euchromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0000995"(RNA polymerase III general transcription initiation factor activity)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0001091"(RNA polymerase II general transcription initiation factor binding)|go:"GO:0001093"(TFIIB-class transcription factor binding)|go:"GO:0001939"(female pronucleus)|go:"GO:0001940"(male pronucleus)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0005672"(transcription factor TFIIA complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006352"(DNA-templated transcription, initiation)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006383"(transcription by RNA polymerase III)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016251"(RNA polymerase II general transcription initiation factor activity)|go:"GO:0017162"(aryl hydrocarbon receptor binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051123"(RNA polymerase II preinitiation complex assembly)|go:"GO:0097550"(transcription preinitiation complex)|go:"GO:0140223"(general transcription initiation factor activity)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR000814(TATA-box binding)|interpro:IPR012295(Beta2-adaptin/TATA-box binding, C-terminal)|interpro:IPR030491|interpro:IPR033710|mint:P20226|rcsb pdb:1C9B|rcsb pdb:1CDW|rcsb pdb:1JFI|rcsb pdb:1NVP|rcsb pdb:1TGH|rcsb pdb:4ROC|rcsb pdb:4ROD|rcsb pdb:4ROE|rcsb pdb:5FUR|rcsb pdb:5IY6|rcsb pdb:5IY7|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5IYA|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|rcsb pdb:5N9G|rcsb pdb:6MZD|rcsb pdb:6MZL|rcsb pdb:6MZM|rcsb pdb:6O9L|rcsb pdb:7EDX|rcsb pdb:7EG7|rcsb pdb:7EG8|rcsb pdb:7EG9|rcsb pdb:7EGA|rcsb pdb:7EGB|rcsb pdb:7EGC|rcsb pdb:7EGD|rcsb pdb:7EGE|rcsb pdb:7EGF|rcsb pdb:7EGI|rcsb pdb:7EGJ|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7LBM|rcsb pdb:7NVR|rcsb pdb:7NVS|rcsb pdb:7NVT|rcsb pdb:7NVU|rcsb pdb:7NVY|rcsb pdb:7NVZ|rcsb pdb:7NW0|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-427359|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-674695|reactome:R-HSA-6804756|reactome:R-HSA-6807505|reactome:R-HSA-73762|reactome:R-HSA-73772|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-73863|reactome:R-HSA-749476|reactome:R-HSA-75953|reactome:R-HSA-76042|reactome:R-HSA-76061|reactome:R-HSA-76066|reactome:R-HSA-76071|reactome:R-HSA-9018519|dip:DIP-1078N	psi-mi:"MI:0465"(dip)	-	-	dip-version:1|dip-updated-by:nodeMerge04|dip-date-update:2013-12-24|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2017/08/05	2017/08/10	rogid:P0LoULOvon+Wp2G17lBlqn3Fo4E9606	rogid:tH4ckPOwO4Icr1YsnJ1Ck/6Cgmo9606	rigid:oB03irp3cwUOoi8139PtEdr719Y	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)