#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q03405-1 uniprotkb:P00749 intact:EBI-15695188|ensembl:ENSP00000339328 intact:EBI-3905042|uniprotkb:Q15844|uniprotkb:B4DPZ2|uniprotkb:Q53XS3|uniprotkb:Q16618|uniprotkb:Q5SWW9|uniprotkb:Q969W6|ensembl:ENSP00000361850 psi-mi:q03405-1(display_long)|uniprotkb:Monocyte activation antigen Mo3(gene name synonym)|uniprotkb:PLAUR(gene name)|psi-mi:PLAUR(display_short)|uniprotkb:MO3(gene name synonym)|uniprotkb:UPAR(gene name synonym)|uniprotkb:uPAR1(isoform synonym)|uniprotkb:GPI-anchored(isoform synonym) psi-mi:urok_human(display_long)|uniprotkb:PLAU(gene name)|psi-mi:PLAU(display_short) psi-mi:"MI:0071"(molecular sieving) Huai et al. (2008) pubmed:18376415|doi:10.1038/nsmb.1404|imex:IM-9641 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15695198|imex:IM-9641-1|dip:DIP-88373E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000011422(gene)|ensembl:ENST00000340093(transcript)|intact:EBI-716505(isoform-parent) refseq:NP_001138503.1|refseq:NP_002649.1|dip:DIP-46387N|refseq:NP_001306120.1|rcsb pdb:4MNX|rcsb pdb:4MNY|rcsb pdb:4OS1|rcsb pdb:4OS2|rcsb pdb:4OS4|rcsb pdb:4OS5|rcsb pdb:4OS6|rcsb pdb:4OS7|rcsb pdb:4X0W|rcsb pdb:4X1N|rcsb pdb:4X1P|rcsb pdb:4X1Q|rcsb pdb:4X1R|rcsb pdb:4X1S|rcsb pdb:4XSK|rcsb pdb:4ZHL|rcsb pdb:4ZHM|rcsb pdb:4ZKN|rcsb pdb:4ZKO|rcsb pdb:4ZKR|rcsb pdb:4ZKS|ensembl:ENSG00000122861(gene)|ensembl:ENST00000372764(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006508"(proteolysis)|go:"GO:0006935"(chemotaxis)|go:"GO:0007165"(signal transduction)|go:"GO:0007596"(blood coagulation)|go:"GO:0009986"(cell surface)|go:"GO:0010469"(regulation of signaling receptor activity)|go:"GO:0014909"(smooth muscle cell migration)|go:"GO:0014910"(regulation of smooth muscle cell migration)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031639"(plasminogen activation)|go:"GO:0033628"(regulation of cell adhesion mediated by integrin)|go:"GO:0035579"(specific granule membrane)|go:"GO:0042730"(fibrinolysis)|go:"GO:0061041"(regulation of wound healing)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070821"(tertiary granule membrane)|go:"GO:2000097"(regulation of smooth muscle cell-matrix adhesion)|interpro:IPR000001(Kringle)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001254(Peptidase S1 and S6, chymotrypsin/Hap)|interpro:IPR001314(Peptidase S1A, chymotrypsin)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR013806(Kringle-like fold)|interpro:IPR018056|interpro:IPR018114|interpro:IPR033116|interpro:IPR034814|interpro:IPR038178|interpro:IPR043504|rcsb pdb:1C5W|rcsb pdb:1C5X|rcsb pdb:1C5Y|rcsb pdb:1C5Z|rcsb pdb:1EJN|rcsb pdb:1F5K|go:"GO:0042127"(regulation of cell population proliferation)|rcsb pdb:1F5L|rcsb pdb:1F92|rcsb pdb:5ZAH|rcsb pdb:5ZAJ|rcsb pdb:5ZC5|rcsb pdb:6AG2|rcsb pdb:6AG3|rcsb pdb:6AG7|rcsb pdb:6AG9|rcsb pdb:6JYP|rcsb pdb:6JYQ|rcsb pdb:6L04|rcsb pdb:6L05|rcsb pdb:6NMB|rcsb pdb:6XVD|reactome:R-HSA-6798695|reactome:R-HSA-75205|rcsb pdb:5HGG|rcsb pdb:5WXF|rcsb pdb:5WXO|rcsb pdb:5WXP|rcsb pdb:5WXQ|rcsb pdb:5WXR|rcsb pdb:5WXS|rcsb pdb:5WXT|rcsb pdb:5XG4|rcsb pdb:5YC6|rcsb pdb:5YC7|rcsb pdb:5Z1C|rcsb pdb:5ZA7|rcsb pdb:5ZA8|rcsb pdb:5ZA9|rcsb pdb:5ZAE|rcsb pdb:5ZAF|rcsb pdb:5ZAG|rcsb pdb:1O5A|rcsb pdb:1O5B|rcsb pdb:1O5C|rcsb pdb:1OWD|rcsb pdb:1OWE|rcsb pdb:1OWH|rcsb pdb:1OWI|rcsb pdb:1OWJ|rcsb pdb:1OWK|rcsb pdb:1SC8|rcsb pdb:1SQA|rcsb pdb:1SQO|rcsb pdb:1SQT|rcsb pdb:1U6Q|rcsb pdb:1URK|rcsb pdb:1VJ9|rcsb pdb:1VJA|rcsb pdb:1W0Z|rcsb pdb:1W10|rcsb pdb:1W11|rcsb pdb:1W12|rcsb pdb:1W13|rcsb pdb:1W14|rcsb pdb:1FV9|rcsb pdb:1GI7|rcsb pdb:1GI8|rcsb pdb:1GI9|rcsb pdb:1GJ7|rcsb pdb:1GJ8|rcsb pdb:1GJ9|rcsb pdb:1GJA|rcsb pdb:1GJB|rcsb pdb:1GJC|rcsb pdb:1GJD|rcsb pdb:1KDU|rcsb pdb:1LMW|rcsb pdb:1O3P|rcsb pdb:2FD6|rcsb pdb:2I9A|rcsb pdb:2I9B|rcsb pdb:2NWN|rcsb pdb:2O8T|rcsb pdb:2O8U|rcsb pdb:2O8W|rcsb pdb:2R2W|rcsb pdb:2VIN|rcsb pdb:2VIO|rcsb pdb:2VIP|rcsb pdb:2VIQ|rcsb pdb:2VIV|rcsb pdb:2VIW|rcsb pdb:2VNT|rcsb pdb:3BT1|rcsb pdb:3BT2|rcsb pdb:3IG6|rcsb pdb:3KGP|rcsb pdb:3KHV|rcsb pdb:3KID|rcsb pdb:3M61|rcsb pdb:3MHW|rcsb pdb:3MWI|rcsb pdb:3OX7|rcsb pdb:3OY5|rcsb pdb:3OY6|rcsb pdb:3PB1|rcsb pdb:3QN7|rcsb pdb:3U73|rcsb pdb:4DVA|rcsb pdb:4DW2|rcsb pdb:4FU7|rcsb pdb:4FU8|rcsb pdb:4FU9|rcsb pdb:4FUB|rcsb pdb:4FUC|rcsb pdb:4FUD|rcsb pdb:4FUE|rcsb pdb:4FUF|rcsb pdb:4FUG|rcsb pdb:4FUH|rcsb pdb:4FUI|rcsb pdb:4FUJ|rcsb pdb:4GLY|rcsb pdb:4H42|rcsb pdb:4JK5|rcsb pdb:4JK6|rcsb pdb:4K24|rcsb pdb:4MNV|rcsb pdb:4MNW psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/05 2017/08/10 rogid:faxxSUpKpPAaAlPpUpvg2NG4DOA9606 rogid:UgdiI+n26oe/Pa7q8Le493SlNE89606 rigid:LD2TjPDWyX8alq83F8kwnyiUBkg false binding-associated region:1-277 binding-associated region:1-143 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q03405-1 uniprotkb:P00749 intact:EBI-15695188|ensembl:ENSP00000339328 intact:EBI-3905042|uniprotkb:Q15844|uniprotkb:B4DPZ2|uniprotkb:Q53XS3|uniprotkb:Q16618|uniprotkb:Q5SWW9|uniprotkb:Q969W6|ensembl:ENSP00000361850 psi-mi:q03405-1(display_long)|uniprotkb:Monocyte activation antigen Mo3(gene name synonym)|uniprotkb:PLAUR(gene name)|psi-mi:PLAUR(display_short)|uniprotkb:MO3(gene name synonym)|uniprotkb:UPAR(gene name synonym)|uniprotkb:uPAR1(isoform synonym)|uniprotkb:GPI-anchored(isoform synonym) psi-mi:urok_human(display_long)|uniprotkb:PLAU(gene name)|psi-mi:PLAU(display_short) psi-mi:"MI:0114"(x-ray crystallography) Huai et al. (2008) pubmed:18376415|doi:10.1038/nsmb.1404|imex:IM-9641 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15695221|imex:IM-9641-2|dip:DIP-88374E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000011422(gene)|ensembl:ENST00000340093(transcript)|intact:EBI-716505(isoform-parent) refseq:NP_001138503.1|refseq:NP_002649.1|dip:DIP-46387N|refseq:NP_001306120.1|rcsb pdb:4MNX|rcsb pdb:4MNY|rcsb pdb:4OS1|rcsb pdb:4OS2|rcsb pdb:4OS4|rcsb pdb:4OS5|rcsb pdb:4OS6|rcsb pdb:4OS7|rcsb pdb:4X0W|rcsb pdb:4X1N|rcsb pdb:4X1P|rcsb pdb:4X1Q|rcsb pdb:4X1R|rcsb pdb:4X1S|rcsb pdb:4XSK|rcsb pdb:4ZHL|rcsb pdb:4ZHM|rcsb pdb:4ZKN|rcsb pdb:4ZKO|rcsb pdb:4ZKR|rcsb pdb:4ZKS|ensembl:ENSG00000122861(gene)|ensembl:ENST00000372764(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006508"(proteolysis)|go:"GO:0006935"(chemotaxis)|go:"GO:0007165"(signal transduction)|go:"GO:0007596"(blood coagulation)|go:"GO:0009986"(cell surface)|go:"GO:0010469"(regulation of signaling receptor activity)|go:"GO:0014909"(smooth muscle cell migration)|go:"GO:0014910"(regulation of smooth muscle cell migration)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031639"(plasminogen activation)|go:"GO:0033628"(regulation of cell adhesion mediated by integrin)|go:"GO:0035579"(specific granule membrane)|go:"GO:0042730"(fibrinolysis)|go:"GO:0061041"(regulation of wound healing)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070821"(tertiary granule membrane)|go:"GO:2000097"(regulation of smooth muscle cell-matrix adhesion)|interpro:IPR000001(Kringle)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001254(Peptidase S1 and S6, chymotrypsin/Hap)|interpro:IPR001314(Peptidase S1A, chymotrypsin)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR013806(Kringle-like fold)|interpro:IPR018056|interpro:IPR018114|interpro:IPR033116|interpro:IPR034814|interpro:IPR038178|interpro:IPR043504|rcsb pdb:1C5W|rcsb pdb:1C5X|rcsb pdb:1C5Y|rcsb pdb:1C5Z|rcsb pdb:1EJN|rcsb pdb:1F5K|go:"GO:0042127"(regulation of cell population proliferation)|rcsb pdb:1F5L|rcsb pdb:1F92|rcsb pdb:5ZAH|rcsb pdb:5ZAJ|rcsb pdb:5ZC5|rcsb pdb:6AG2|rcsb pdb:6AG3|rcsb pdb:6AG7|rcsb pdb:6AG9|rcsb pdb:6JYP|rcsb pdb:6JYQ|rcsb pdb:6L04|rcsb pdb:6L05|rcsb pdb:6NMB|rcsb pdb:6XVD|reactome:R-HSA-6798695|reactome:R-HSA-75205|rcsb pdb:5HGG|rcsb pdb:5WXF|rcsb pdb:5WXO|rcsb pdb:5WXP|rcsb pdb:5WXQ|rcsb pdb:5WXR|rcsb pdb:5WXS|rcsb pdb:5WXT|rcsb pdb:5XG4|rcsb pdb:5YC6|rcsb pdb:5YC7|rcsb pdb:5Z1C|rcsb pdb:5ZA7|rcsb pdb:5ZA8|rcsb pdb:5ZA9|rcsb pdb:5ZAE|rcsb pdb:5ZAF|rcsb pdb:5ZAG|rcsb pdb:1O5A|rcsb pdb:1O5B|rcsb pdb:1O5C|rcsb pdb:1OWD|rcsb pdb:1OWE|rcsb pdb:1OWH|rcsb pdb:1OWI|rcsb pdb:1OWJ|rcsb pdb:1OWK|rcsb pdb:1SC8|rcsb pdb:1SQA|rcsb pdb:1SQO|rcsb pdb:1SQT|rcsb pdb:1U6Q|rcsb pdb:1URK|rcsb pdb:1VJ9|rcsb pdb:1VJA|rcsb pdb:1W0Z|rcsb pdb:1W10|rcsb pdb:1W11|rcsb pdb:1W12|rcsb pdb:1W13|rcsb pdb:1W14|rcsb pdb:1FV9|rcsb pdb:1GI7|rcsb pdb:1GI8|rcsb pdb:1GI9|rcsb pdb:1GJ7|rcsb pdb:1GJ8|rcsb pdb:1GJ9|rcsb pdb:1GJA|rcsb pdb:1GJB|rcsb pdb:1GJC|rcsb pdb:1GJD|rcsb pdb:1KDU|rcsb pdb:1LMW|rcsb pdb:1O3P|rcsb pdb:2FD6|rcsb pdb:2I9A|rcsb pdb:2I9B|rcsb pdb:2NWN|rcsb pdb:2O8T|rcsb pdb:2O8U|rcsb pdb:2O8W|rcsb pdb:2R2W|rcsb pdb:2VIN|rcsb pdb:2VIO|rcsb pdb:2VIP|rcsb pdb:2VIQ|rcsb pdb:2VIV|rcsb pdb:2VIW|rcsb pdb:2VNT|rcsb pdb:3BT1|rcsb pdb:3BT2|rcsb pdb:3IG6|rcsb pdb:3KGP|rcsb pdb:3KHV|rcsb pdb:3KID|rcsb pdb:3M61|rcsb pdb:3MHW|rcsb pdb:3MWI|rcsb pdb:3OX7|rcsb pdb:3OY5|rcsb pdb:3OY6|rcsb pdb:3PB1|rcsb pdb:3QN7|rcsb pdb:3U73|rcsb pdb:4DVA|rcsb pdb:4DW2|rcsb pdb:4FU7|rcsb pdb:4FU8|rcsb pdb:4FU9|rcsb pdb:4FUB|rcsb pdb:4FUC|rcsb pdb:4FUD|rcsb pdb:4FUE|rcsb pdb:4FUF|rcsb pdb:4FUG|rcsb pdb:4FUH|rcsb pdb:4FUI|rcsb pdb:4FUJ|rcsb pdb:4GLY|rcsb pdb:4H42|rcsb pdb:4JK5|rcsb pdb:4JK6|rcsb pdb:4K24|rcsb pdb:4MNV|rcsb pdb:4MNW psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/05 2017/08/10 rogid:faxxSUpKpPAaAlPpUpvg2NG4DOA9606 rogid:UgdiI+n26oe/Pa7q8Le493SlNE89606 rigid:vNuF4mS1ZUOFnSUqAvwcjrOKJuc false binding-associated region:1-277 binding-associated region:1-143 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q03405-1 uniprotkb:P04004 intact:EBI-15695188|ensembl:ENSP00000339328 intact:EBI-1036653|uniprotkb:P01141|uniprotkb:Q9BSH7|uniprotkb:B2R7G0|ensembl:ENSP00000226218 psi-mi:q03405-1(display_long)|uniprotkb:Monocyte activation antigen Mo3(gene name synonym)|uniprotkb:PLAUR(gene name)|psi-mi:PLAUR(display_short)|uniprotkb:MO3(gene name synonym)|uniprotkb:UPAR(gene name synonym)|uniprotkb:uPAR1(isoform synonym)|uniprotkb:GPI-anchored(isoform synonym) psi-mi:vtnc_human(display_long)|uniprotkb:VTN(gene name)|psi-mi:VTN(display_short)|uniprotkb:Serum-spreading factor(gene name synonym)|uniprotkb:V75(gene name synonym)|uniprotkb:S-protein(gene name synonym) psi-mi:"MI:0114"(x-ray crystallography) Huai et al. (2008) pubmed:18376415|doi:10.1038/nsmb.1404|imex:IM-9641 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15695221|imex:IM-9641-2|dip:DIP-88374E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000011422(gene)|ensembl:ENST00000340093(transcript)|intact:EBI-716505(isoform-parent) refseq:NP_000629.3|ensembl:ENSG00000109072(gene)|ensembl:ENST00000226218(transcript)|go:"GO:0005044"(scavenger receptor activity)|go:"GO:0005178"(integrin binding)|go:"GO:0005201"(extracellular matrix structural constituent)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006955"(immune response)|go:"GO:0007155"(cell adhesion)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0008201"(heparin binding)|go:"GO:0010951"(negative regulation of endopeptidase activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016477"(cell migration)|go:"GO:0030195"(negative regulation of blood coagulation)|go:"GO:0030247"(polysaccharide binding)|go:"GO:0030949"(positive regulation of vascular endothelial growth factor receptor signaling pathway)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0033627"(cell adhesion mediated by integrin)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048260"(positive regulation of receptor-mediated endocytosis)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0061302"(smooth muscle cell-matrix adhesion)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071062"(alphav-beta3 integrin-vitronectin complex)|go:"GO:0072562"(blood microparticle)|go:"GO:0090303"(positive regulation of wound healing)|interpro:IPR000585(Hemopexin)|interpro:IPR001212(Somatomedin B)|interpro:IPR018486|interpro:IPR018487|interpro:IPR020436|interpro:IPR036024|interpro:IPR036375|mint:P04004|rcsb pdb:1OC0|rcsb pdb:1S4G|rcsb pdb:1SSU|rcsb pdb:2JQ8|rcsb pdb:3BT1|rcsb pdb:3BT2|rcsb pdb:4K24|rcsb pdb:6O5E|reactome:R-HSA-2129379|reactome:R-HSA-216083|reactome:R-HSA-3000170|reactome:R-HSA-3000178|reactome:R-HSA-977606|dip:DIP-36566N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/05 2017/08/10 rogid:faxxSUpKpPAaAlPpUpvg2NG4DOA9606 rogid:07qxfQS6kbUZGwPyNj8/LTetT6I9606 rigid:vNuF4mS1ZUOFnSUqAvwcjrOKJuc false binding-associated region:1-277 binding-associated region:1-50 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)