#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P47992 uniprotkb:P47992 intact:EBI-10209901|uniprotkb:Q52MA8|ensembl:ENSP00000356792 intact:EBI-10209901|uniprotkb:Q52MA8|ensembl:ENSP00000356792 psi-mi:xcl1_human(display_long)|uniprotkb:XCL1(gene name)|psi-mi:XCL1(display_short)|uniprotkb:ATAC(gene name synonym)|uniprotkb:C motif chemokine 1(gene name synonym)|uniprotkb:Cytokine SCM-1(gene name synonym)|uniprotkb:LTN(gene name synonym)|uniprotkb:Lymphotaxin(gene name synonym)|uniprotkb:SCM-1-alpha(gene name synonym)|uniprotkb:SCYC1(gene name synonym)|uniprotkb:Small-inducible cytokine C1(gene name synonym)|uniprotkb:XC chemokine ligand 1(gene name synonym) psi-mi:xcl1_human(display_long)|uniprotkb:XCL1(gene name)|psi-mi:XCL1(display_short)|uniprotkb:ATAC(gene name synonym)|uniprotkb:C motif chemokine 1(gene name synonym)|uniprotkb:Cytokine SCM-1(gene name synonym)|uniprotkb:LTN(gene name synonym)|uniprotkb:Lymphotaxin(gene name synonym)|uniprotkb:SCM-1-alpha(gene name synonym)|uniprotkb:SCYC1(gene name synonym)|uniprotkb:Small-inducible cytokine C1(gene name synonym)|uniprotkb:XC chemokine ligand 1(gene name synonym) psi-mi:"MI:0077"(nuclear magnetic resonance) Tuinstra et al. (2008) pubmed:18364395|doi:10.1073/pnas.0709518105|imex:IM-9204 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15694878|imex:IM-9204-1|dip:DIP-59374E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002986.1|refseq:XP_011508167.1|go:"GO:0048247"(lymphocyte chemotaxis)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0051209"(release of sequestered calcium ion into cytosol)|go:"GO:0051281"(positive regulation of release of sequestered calcium ion into cytosol)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:"GO:0070098"(chemokine-mediated signaling pathway)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0071636"(positive regulation of transforming growth factor beta production)|go:"GO:0071663"(positive regulation of granzyme B production)|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:2000412"(positive regulation of thymocyte migration)|go:"GO:2000503"(positive regulation of natural killer cell chemotaxis)|go:"GO:2000513"(positive regulation of granzyme A production)|go:"GO:2000518"(negative regulation of T-helper 1 cell activation)|go:"GO:2000538"(positive regulation of B cell chemotaxis)|go:"GO:2000553"(positive regulation of T-helper 2 cell cytokine production)|go:"GO:2000556"(positive regulation of T-helper 1 cell cytokine production)|go:"GO:2000558"(positive regulation of immunoglobulin production in mucosal tissue)|go:"GO:2000562"(negative regulation of CD4-positive, alpha-beta T cell proliferation)|go:"GO:2000563"(positive regulation of CD4-positive, alpha-beta T cell proliferation)|go:"GO:2000566"(positive regulation of CD8-positive, alpha-beta T cell proliferation)|interpro:IPR001811(Small chemokine, interleukin-8-like)|interpro:IPR008105(Lymphotactin precursor)|interpro:IPR036048|interpro:IPR039809|rcsb pdb:1J8I|rcsb pdb:1J9O|rcsb pdb:2HDM|rcsb pdb:2JP1|rcsb pdb:2N54|rcsb pdb:2NYZ|reactome:R-HSA-380108|reactome:R-HSA-416476|ensembl:ENSG00000143184(gene)|ensembl:ENST00000367818(transcript)|go:"GO:0001916"(positive regulation of T cell mediated cytotoxicity)|go:"GO:0002548"(monocyte chemotaxis)|go:"GO:0002690"(positive regulation of leukocyte chemotaxis)|go:"GO:0002725"(negative regulation of T cell cytokine production)|go:"GO:0002726"(positive regulation of T cell cytokine production)|go:"GO:0002826"(negative regulation of T-helper 1 type immune response)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0006954"(inflammatory response)|go:"GO:0007165"(signal transduction)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008009"(chemokine activity)|go:"GO:0009615"(response to virus)|go:"GO:0010820"(positive regulation of T cell chemotaxis)|go:"GO:0030593"(neutrophil chemotaxis)|go:"GO:0031640"(killing of cells of another organism)|go:"GO:0032689"(negative regulation of interferon-gamma production)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0032733"(positive regulation of interleukin-10 production)|go:"GO:0035782"(mature natural killer cell chemotaxis)|go:"GO:0042379"(chemokine receptor binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048020"(CCR chemokine receptor binding)|dip:DIP-29876N refseq:NP_002986.1|refseq:XP_011508167.1|go:"GO:0048247"(lymphocyte chemotaxis)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0051209"(release of sequestered calcium ion into cytosol)|go:"GO:0051281"(positive regulation of release of sequestered calcium ion into cytosol)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:"GO:0070098"(chemokine-mediated signaling pathway)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0071636"(positive regulation of transforming growth factor beta production)|go:"GO:0071663"(positive regulation of granzyme B production)|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:2000412"(positive regulation of thymocyte migration)|go:"GO:2000503"(positive regulation of natural killer cell chemotaxis)|go:"GO:2000513"(positive regulation of granzyme A production)|go:"GO:2000518"(negative regulation of T-helper 1 cell activation)|go:"GO:2000538"(positive regulation of B cell chemotaxis)|go:"GO:2000553"(positive regulation of T-helper 2 cell cytokine production)|go:"GO:2000556"(positive regulation of T-helper 1 cell cytokine production)|go:"GO:2000558"(positive regulation of immunoglobulin production in mucosal tissue)|go:"GO:2000562"(negative regulation of CD4-positive, alpha-beta T cell proliferation)|go:"GO:2000563"(positive regulation of CD4-positive, alpha-beta T cell proliferation)|go:"GO:2000566"(positive regulation of CD8-positive, alpha-beta T cell proliferation)|interpro:IPR001811(Small chemokine, interleukin-8-like)|interpro:IPR008105(Lymphotactin precursor)|interpro:IPR036048|interpro:IPR039809|rcsb pdb:1J8I|rcsb pdb:1J9O|rcsb pdb:2HDM|rcsb pdb:2JP1|rcsb pdb:2N54|rcsb pdb:2NYZ|reactome:R-HSA-380108|reactome:R-HSA-416476|ensembl:ENSG00000143184(gene)|ensembl:ENST00000367818(transcript)|go:"GO:0001916"(positive regulation of T cell mediated cytotoxicity)|go:"GO:0002548"(monocyte chemotaxis)|go:"GO:0002690"(positive regulation of leukocyte chemotaxis)|go:"GO:0002725"(negative regulation of T cell cytokine production)|go:"GO:0002726"(positive regulation of T cell cytokine production)|go:"GO:0002826"(negative regulation of T-helper 1 type immune response)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0006954"(inflammatory response)|go:"GO:0007165"(signal transduction)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008009"(chemokine activity)|go:"GO:0009615"(response to virus)|go:"GO:0010820"(positive regulation of T cell chemotaxis)|go:"GO:0030593"(neutrophil chemotaxis)|go:"GO:0031640"(killing of cells of another organism)|go:"GO:0032689"(negative regulation of interferon-gamma production)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0032733"(positive regulation of interleukin-10 production)|go:"GO:0035782"(mature natural killer cell chemotaxis)|go:"GO:0042379"(chemokine receptor binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048020"(CCR chemokine receptor binding)|dip:DIP-29876N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/05 2017/08/10 rogid:DRRNNQxttFRNuXdLAqzUany8MTQ9606 rogid:DRRNNQxttFRNuXdLAqzUany8MTQ9606 rigid:cwFRJF3PIs5KXbsCyWfvsfjlSWo false binding-associated region:22-114 binding-associated region:22-114 - 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)