#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q10426 uniprotkb:Q10103 intact:EBI-1111936|uniprotkb:Q9USN9|uniprotkb:Q9UUL7|ensemblfungi:"SPCC11E10.08.1:pep" intact:EBI-421832|ensemblfungi:"SPAC18G6.02c.1:pep" psi-mi:rik1_schpo(display_long)|uniprotkb:rik1(gene name)|psi-mi:rik1(display_short)|uniprotkb:SPCC11E10.08(orf name)|uniprotkb:Silencing protein rik1(gene name synonym) psi-mi:chp1_schpo(display_long)|uniprotkb:chp1(gene name)|psi-mi:chp1(display_short)|uniprotkb:SPAC18G6.02c(orf name) psi-mi:"MI:0676"(tandem affinity purification) Zhang et al. (2008) pubmed:18345014|doi:10.1038/nsmb.1406|imex:IM-9640 taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15693668|imex:IM-9640-2|dip:DIP-88370E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_588204.1|ensemblfungi:SPCC11E10.08(gene)|ensemblfungi:SPCC11E10.08.1(transcript)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0005816"(spindle pole body)|go:"GO:0006281"(DNA repair)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0043494"(CLRC complex)|go:"GO:0045141"(meiotic telomere clustering)|interpro:IPR004871(Cleavage and polyadenylation specificity factor, A subunit, C-terminal)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018846|interpro:IPR031297|dip:DIP-35634N refseq:NP_593666.1|ensemblfungi:SPAC18G6.02c(gene)|ensemblfungi:SPAC18G6.02c.1(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005737"(cytoplasm)|go:"GO:0005816"(spindle pole body)|go:"GO:0007049"(cell cycle)|go:"GO:0007059"(chromosome segregation)|go:"GO:0030958"(RITS complex)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0031048"(heterochromatin assembly by small RNA)|go:"GO:0031493"(obsolete nucleosomal histone binding)|go:"GO:0031508"(pericentric heterochromatin assembly)|go:"GO:0031934"(mating-type region heterochromatin)|go:"GO:0034507"(chromosome, centromeric outer repeat region)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035064"(methylated histone binding)|go:"GO:0071459"(protein localization to chromosome, centromeric region)|go:"GO:0099115"(chromosome, subtelomeric region)|go:"GO:1990342"(heterochromatin island)|interpro:IPR000953(Chromo domain)|interpro:IPR016197(Chromo domain-like)|interpro:IPR023779|interpro:IPR023780|interpro:IPR035979|rcsb pdb:2RSN|rcsb pdb:3G7L|rcsb pdb:3TIX|dip:DIP-29301N|reactome:R-SPO-73772|reactome:R-SPO-983231 psi-mi:"MI:0465"(dip) crc64:0C76BB59E1215BF1 crc64:E92C16BBD0D5957C full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4896(schpm)|taxid:4896("Schizosaccharomyces pombe (fission yeast)") - 2017/08/05 2017/08/10 rogid:t1LBwviHXmmvKSMrLCcs2QCSp2Q284812 rogid:52dapo2Xglte9lzhLJh120xLS/g284812 rigid:9hTyazS/TzF9sKqVxetJ24/9CcA false tandem tag:c-c - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q10103 uniprotkb:O60016 intact:EBI-421832|ensemblfungi:"SPAC18G6.02c.1:pep" intact:EBI-354657|uniprotkb:O74565|ensemblfungi:"SPBC428.08c.1:pep" psi-mi:chp1_schpo(display_long)|uniprotkb:chp1(gene name)|psi-mi:chp1(display_short)|uniprotkb:SPAC18G6.02c(orf name) psi-mi:clr4_schpo(display_long)|uniprotkb:clr4(gene name)|psi-mi:clr4(display_short)|uniprotkb:SPBC428.08c(orf name)|uniprotkb:kmt1(gene name synonym)|uniprotkb:Histone H3-K9 methyltransferase(gene name synonym)|uniprotkb:Cryptic loci regulator 4(gene name synonym)|uniprotkb:Lysine N-methyltransferase 1(gene name synonym)|uniprotkb:Protein lysine methyltransferase clr4(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Zhang et al. (2008) pubmed:18345014|doi:10.1038/nsmb.1406|imex:IM-9640 taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15693687|imex:IM-9640-3|dip:DIP-88371E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_593666.1|ensemblfungi:SPAC18G6.02c(gene)|ensemblfungi:SPAC18G6.02c.1(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005737"(cytoplasm)|go:"GO:0005816"(spindle pole body)|go:"GO:0007049"(cell cycle)|go:"GO:0007059"(chromosome segregation)|go:"GO:0030958"(RITS complex)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0031048"(heterochromatin assembly by small RNA)|go:"GO:0031493"(obsolete nucleosomal histone binding)|go:"GO:0031508"(pericentric heterochromatin assembly)|go:"GO:0031934"(mating-type region heterochromatin)|go:"GO:0034507"(chromosome, centromeric outer repeat region)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035064"(methylated histone binding)|go:"GO:0071459"(protein localization to chromosome, centromeric region)|go:"GO:0099115"(chromosome, subtelomeric region)|go:"GO:1990342"(heterochromatin island)|interpro:IPR000953(Chromo domain)|interpro:IPR016197(Chromo domain-like)|interpro:IPR023779|interpro:IPR023780|interpro:IPR035979|rcsb pdb:2RSN|rcsb pdb:3G7L|rcsb pdb:3TIX|dip:DIP-29301N|reactome:R-SPO-73772|reactome:R-SPO-983231 refseq:NP_595186.1|ensemblfungi:SPBC428.08c(gene)|ensemblfungi:SPBC428.08c.1(transcript)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005737"(cytoplasm)|go:"GO:0005816"(spindle pole body)|go:"GO:0007535"(donor selection)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|go:"GO:0031508"(pericentric heterochromatin assembly)|go:"GO:0031934"(mating-type region heterochromatin)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035064"(methylated histone binding)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043494"(CLRC complex)|go:"GO:0045141"(meiotic telomere clustering)|go:"GO:0046974"("histone methyltransferase activity (H3-K9 specific)")|go:"GO:0070314"(G1 to G0 transition)|go:"GO:0070829"(obsolete heterochromatin maintenance)|go:"GO:0090053"(positive regulation of pericentric heterochromatin assembly)|go:"GO:0099115"(chromosome, subtelomeric region)|go:"GO:1902682"(protein localization to pericentric heterochromatin)|go:"GO:1903212"(protein localization to mating-type region heterochromatin)|interpro:IPR000953(Chromo domain)|interpro:IPR001214(SET)|interpro:IPR003616(Post-SET zinc-binding region)|interpro:IPR007728(Pre-SET zinc-binding region)|interpro:IPR011381(Histone H3-K9 methyltransferase)|interpro:IPR016197(Chromo domain-like)|interpro:IPR023779|interpro:IPR023780|rcsb pdb:1G6Z|rcsb pdb:1MVH|rcsb pdb:1MVX|rcsb pdb:6BOX|rcsb pdb:6BP4|dip:DIP-32588N psi-mi:"MI:0465"(dip) crc64:E92C16BBD0D5957C crc64:53C3EC87BCBA51FF full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4896(schpm)|taxid:4896("Schizosaccharomyces pombe (fission yeast)") - 2017/08/05 2017/08/10 rogid:52dapo2Xglte9lzhLJh120xLS/g284812 rogid:eUv/KQk3smVMRj/BSTYSDOw/vUY284812 rigid:9ZmV8C6stlp7fEKsrlNDIyyrKtc false - flag tag:n-n - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) intact:EBI-15693706 uniprotkb:O60016 dip:DIP-46180N intact:EBI-354657|uniprotkb:O74565|ensemblfungi:"SPBC428.08c.1:pep" psi-mi:h3k9me3(display_short)|psi-mi:EBI-15693706(display_long) psi-mi:clr4_schpo(display_long)|uniprotkb:clr4(gene name)|psi-mi:clr4(display_short)|uniprotkb:SPBC428.08c(orf name)|uniprotkb:kmt1(gene name synonym)|uniprotkb:Histone H3-K9 methyltransferase(gene name synonym)|uniprotkb:Cryptic loci regulator 4(gene name synonym)|uniprotkb:Lysine N-methyltransferase 1(gene name synonym)|uniprotkb:Protein lysine methyltransferase clr4(gene name synonym) psi-mi:"MI:0053"(fluorescence polarization spectroscopy) Zhang et al. (2008) pubmed:18345014|doi:10.1038/nsmb.1406|imex:IM-9640 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15693709|imex:IM-9640-1|dip:DIP-88372E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0327"(peptide) psi-mi:"MI:0326"(protein) - refseq:NP_595186.1|ensemblfungi:SPBC428.08c(gene)|ensemblfungi:SPBC428.08c.1(transcript)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005737"(cytoplasm)|go:"GO:0005816"(spindle pole body)|go:"GO:0007535"(donor selection)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|go:"GO:0031508"(pericentric heterochromatin assembly)|go:"GO:0031934"(mating-type region heterochromatin)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035064"(methylated histone binding)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043494"(CLRC complex)|go:"GO:0045141"(meiotic telomere clustering)|go:"GO:0046974"("histone methyltransferase activity (H3-K9 specific)")|go:"GO:0070314"(G1 to G0 transition)|go:"GO:0070829"(obsolete heterochromatin maintenance)|go:"GO:0090053"(positive regulation of pericentric heterochromatin assembly)|go:"GO:0099115"(chromosome, subtelomeric region)|go:"GO:1902682"(protein localization to pericentric heterochromatin)|go:"GO:1903212"(protein localization to mating-type region heterochromatin)|interpro:IPR000953(Chromo domain)|interpro:IPR001214(SET)|interpro:IPR003616(Post-SET zinc-binding region)|interpro:IPR007728(Pre-SET zinc-binding region)|interpro:IPR011381(Histone H3-K9 methyltransferase)|interpro:IPR016197(Chromo domain-like)|interpro:IPR023779|interpro:IPR023780|rcsb pdb:1G6Z|rcsb pdb:1MVH|rcsb pdb:1MVX|rcsb pdb:6BOX|rcsb pdb:6BP4|dip:DIP-32588N psi-mi:"MI:0465"(dip) - crc64:53C3EC87BCBA51FF full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/05 2017/08/10 rogid:j+Vs6hl6rR++ybJ2qjUPaG8Fldk-2 rogid:eUv/KQk3smVMRj/BSTYSDOw/vUY284812 rigid:dJd3HFbA5/iP3dfKOT1jkyHZFBY false - sufficient binding region:8-69|mutation disrupting interaction:31-31|mutation disrupting interaction:41-41 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)