#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q3UHN9 uniprotkb:P70428 intact:EBI-15693148|ensembl:ENSMUSP00000126623|ensembl:ENSMUSP00000158312|uniprotkb:O70353|uniprotkb:Q3TBX3|uniprotkb:Q3TDS3|uniprotkb:Q8BZE5|uniprotkb:Q9R206 intact:EBI-15693102|ensembl:ENSMUSP00000028623|uniprotkb:P70395|uniprotkb:Q3TPI7|uniprotkb:Q923D6 psi-mi:ndst1_mouse(display_long)|uniprotkb:Ndst1(gene name)|psi-mi:Ndst1(display_short)|uniprotkb:Glucosaminyl N-deacetylase/N-sulfotransferase 1(gene name synonym)|uniprotkb:N-heparan sulfate sulfotransferase 1(gene name synonym)|uniprotkb:[Heparan sulfate]-glucosamine N-sulfotransferase 1(gene name synonym) psi-mi:ext2_mouse(display_long)|uniprotkb:Ext2(gene name)|psi-mi:Ext2(display_short)|uniprotkb:Glucuronosyl-N-acetylglucosaminyl-proteoglycan/N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase(gene name synonym)|uniprotkb:Multiple exostoses protein 2 homolog(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Presto et al. (2008) pubmed:18337501|doi:10.1073/pnas.0705807105|imex:IM-9193 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15693206|imex:IM-9193-1|dip:DIP-59358E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000054008(gene)|ensembl:ENSMUST00000169273(transcript)|ensembl:ENSMUST00000237783(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000271"(polysaccharide biosynthetic process)|go:"GO:0003279"(cardiac septum development)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006476"(protein deacetylation)|go:"GO:0006477"(protein sulfation)|go:"GO:0006954"(inflammatory response)|go:"GO:0007507"(heart development)|go:"GO:0007585"(respiratory gaseous exchange by respiratory system)|go:"GO:0008146"(sulfotransferase activity)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0015012"(heparan sulfate proteoglycan biosynthetic process)|go:"GO:0015016"([heparan sulfate]-glucosamine N-sulfotransferase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019213"(deacetylase activity)|go:"GO:0015014"(heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process)|go:"GO:0030203"(glycosaminoglycan metabolic process)|go:"GO:0030210"(heparin biosynthetic process)|go:"GO:0030900"(forebrain development)|go:"GO:0030901"(midbrain development)|go:"GO:0035904"(aorta development)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0045880"(positive regulation of smoothened signaling pathway)|go:"GO:0048702"(embryonic neurocranium morphogenesis)|go:"GO:0048703"(embryonic viscerocranium morphogenesis)|go:"GO:0060976"(coronary vasculature development)|go:"GO:0102140"(heparan sulfate N-deacetylase activity)|interpro:IPR000863(Sulphotransferase)|interpro:IPR021930|interpro:IPR027417|interpro:IPR037359|reactome:R-MMU-2022928|dip:DIP-29859N|refseq:NP_032332.2|refseq:XP_006525730.1|refseq:XP_006525731.1|refseq:XP_006525732.1|refseq:XP_006525733.1|refseq:XP_006525734.1|refseq:XP_011245146.1|refseq:NP_001335029.1|refseq:NP_001335030.1|refseq:NP_001335031.1|refseq:NP_001335032.1|refseq:NP_001335075.1 ensembl:ENSMUSG00000027198(gene)|ensembl:ENSMUST00000028623(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001503"(ossification)|go:"GO:0001707"(mesoderm formation)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006024"(glycosaminoglycan biosynthetic process)|go:"GO:0006487"(protein N-linked glycosylation)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0008375"(acetylglucosaminyltransferase activity)|go:"GO:0010467"(gene expression)|go:"GO:0015012"(heparan sulfate proteoglycan biosynthetic process)|go:"GO:0015014"(heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process)|go:"GO:0015020"(glucuronosyltransferase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016757"(glycosyltransferase activity)|go:"GO:0030154"(cell differentiation)|go:"GO:0030210"(heparin biosynthetic process)|go:"GO:0033692"(cellular polysaccharide biosynthetic process)|go:"GO:0042044"(fluid transport)|go:"GO:0042311"(vasodilation)|go:"GO:0042328"(heparan sulfate N-acetylglucosaminyltransferase activity)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043541"(UDP-N-acetylglucosamine transferase complex)|go:"GO:0044344"(cellular response to fibroblast growth factor stimulus)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050508"(glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity)|go:"GO:0050509"(N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity)|go:"GO:0050891"(multicellular organismal water homeostasis)|go:"GO:0051923"(sulfation)|go:"GO:0055078"(sodium ion homeostasis)|go:"GO:0060047"(heart contraction)|go:"GO:0060350"(endochondral bone morphogenesis)|interpro:IPR004263(Exostosin-like)|interpro:IPR015338(EXTL2, alpha-1,4-N-acetylhexosaminyltransferase)|interpro:IPR027673|interpro:IPR029044|interpro:IPR040911|reactome:R-MMU-2022928|dip:DIP-29858N|refseq:NP_034293.2|refseq:XP_006498796.1 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/05 2017/08/10 rogid:PFwgIgaJkB8QURpo971bNSC8wZg10090 rogid:f+zVgljsHr6o93gzFx1nVrRdOeg10090 rigid:nvOp3SkTA4UUI8ys5JzXDnWqSyw false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q3UHN9 uniprotkb:P70428 intact:EBI-15693148|ensembl:ENSMUSP00000126623|ensembl:ENSMUSP00000158312|uniprotkb:O70353|uniprotkb:Q3TBX3|uniprotkb:Q3TDS3|uniprotkb:Q8BZE5|uniprotkb:Q9R206 intact:EBI-15693102|ensembl:ENSMUSP00000028623|uniprotkb:P70395|uniprotkb:Q3TPI7|uniprotkb:Q923D6 psi-mi:ndst1_mouse(display_long)|uniprotkb:Ndst1(gene name)|psi-mi:Ndst1(display_short)|uniprotkb:Glucosaminyl N-deacetylase/N-sulfotransferase 1(gene name synonym)|uniprotkb:N-heparan sulfate sulfotransferase 1(gene name synonym)|uniprotkb:[Heparan sulfate]-glucosamine N-sulfotransferase 1(gene name synonym) psi-mi:ext2_mouse(display_long)|uniprotkb:Ext2(gene name)|psi-mi:Ext2(display_short)|uniprotkb:Glucuronosyl-N-acetylglucosaminyl-proteoglycan/N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase(gene name synonym)|uniprotkb:Multiple exostoses protein 2 homolog(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Presto et al. (2008) pubmed:18337501|doi:10.1073/pnas.0705807105|imex:IM-9193 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15693223|imex:IM-9193-2|dip:DIP-59358E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000054008(gene)|ensembl:ENSMUST00000169273(transcript)|ensembl:ENSMUST00000237783(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000271"(polysaccharide biosynthetic process)|go:"GO:0003279"(cardiac septum development)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006476"(protein deacetylation)|go:"GO:0006477"(protein sulfation)|go:"GO:0006954"(inflammatory response)|go:"GO:0007507"(heart development)|go:"GO:0007585"(respiratory gaseous exchange by respiratory system)|go:"GO:0008146"(sulfotransferase activity)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0015012"(heparan sulfate proteoglycan biosynthetic process)|go:"GO:0015016"([heparan sulfate]-glucosamine N-sulfotransferase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019213"(deacetylase activity)|go:"GO:0015014"(heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process)|go:"GO:0030203"(glycosaminoglycan metabolic process)|go:"GO:0030210"(heparin biosynthetic process)|go:"GO:0030900"(forebrain development)|go:"GO:0030901"(midbrain development)|go:"GO:0035904"(aorta development)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0045880"(positive regulation of smoothened signaling pathway)|go:"GO:0048702"(embryonic neurocranium morphogenesis)|go:"GO:0048703"(embryonic viscerocranium morphogenesis)|go:"GO:0060976"(coronary vasculature development)|go:"GO:0102140"(heparan sulfate N-deacetylase activity)|interpro:IPR000863(Sulphotransferase)|interpro:IPR021930|interpro:IPR027417|interpro:IPR037359|reactome:R-MMU-2022928|dip:DIP-29859N|refseq:NP_032332.2|refseq:XP_006525730.1|refseq:XP_006525731.1|refseq:XP_006525732.1|refseq:XP_006525733.1|refseq:XP_006525734.1|refseq:XP_011245146.1|refseq:NP_001335029.1|refseq:NP_001335030.1|refseq:NP_001335031.1|refseq:NP_001335032.1|refseq:NP_001335075.1 ensembl:ENSMUSG00000027198(gene)|ensembl:ENSMUST00000028623(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001503"(ossification)|go:"GO:0001707"(mesoderm formation)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006024"(glycosaminoglycan biosynthetic process)|go:"GO:0006487"(protein N-linked glycosylation)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0008375"(acetylglucosaminyltransferase activity)|go:"GO:0010467"(gene expression)|go:"GO:0015012"(heparan sulfate proteoglycan biosynthetic process)|go:"GO:0015014"(heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process)|go:"GO:0015020"(glucuronosyltransferase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016757"(glycosyltransferase activity)|go:"GO:0030154"(cell differentiation)|go:"GO:0030210"(heparin biosynthetic process)|go:"GO:0033692"(cellular polysaccharide biosynthetic process)|go:"GO:0042044"(fluid transport)|go:"GO:0042311"(vasodilation)|go:"GO:0042328"(heparan sulfate N-acetylglucosaminyltransferase activity)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043541"(UDP-N-acetylglucosamine transferase complex)|go:"GO:0044344"(cellular response to fibroblast growth factor stimulus)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050508"(glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity)|go:"GO:0050509"(N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity)|go:"GO:0050891"(multicellular organismal water homeostasis)|go:"GO:0051923"(sulfation)|go:"GO:0055078"(sodium ion homeostasis)|go:"GO:0060047"(heart contraction)|go:"GO:0060350"(endochondral bone morphogenesis)|interpro:IPR004263(Exostosin-like)|interpro:IPR015338(EXTL2, alpha-1,4-N-acetylhexosaminyltransferase)|interpro:IPR027673|interpro:IPR029044|interpro:IPR040911|reactome:R-MMU-2022928|dip:DIP-29858N|refseq:NP_034293.2|refseq:XP_006498796.1 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/05 2017/08/10 rogid:PFwgIgaJkB8QURpo971bNSC8wZg10090 rogid:f+zVgljsHr6o93gzFx1nVrRdOeg10090 rigid:nvOp3SkTA4UUI8ys5JzXDnWqSyw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)