#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q8TAP4 uniprotkb:O43679 intact:EBI-742259|uniprotkb:Q58A66|uniprotkb:Q8N974|uniprotkb:Q9UDD5|ensembl:ENSP00000312856|ensembl:ENSP00000346689|ensembl:ENSP00000412479|ensembl:ENSP00000413703|ensembl:ENSP00000439275|ensembl:ENSP00000440099|ensembl:ENSP00000444393|ensembl:ENSP00000445751|ensembl:ENSP00000446115|uniprotkb:B4DH35|uniprotkb:Q58A67|uniprotkb:B4DG90 intact:EBI-2865580|uniprotkb:O75480|uniprotkb:O60619|ensembl:ENSP00000306772 psi-mi:lmo3_human(display_long)|uniprotkb:LMO3(gene name)|psi-mi:LMO3(display_short)|uniprotkb:RBTN3(gene name synonym)|uniprotkb:RHOM3(gene name synonym)|uniprotkb:Neuronal-specific transcription factor DAT1(gene name synonym)|uniprotkb:Rhombotin-3(gene name synonym)|uniprotkb:RBTNL2(gene name synonym) psi-mi:ldb2_human(display_long)|uniprotkb:LDB2(gene name)|psi-mi:LDB2(display_short)|uniprotkb:CLIM1(gene name synonym)|uniprotkb:Carboxyl-terminal LIM domain-binding protein 1(gene name synonym)|uniprotkb:LIM domain-binding factor CLIM1(gene name synonym) psi-mi:"MI:0018"(two hybrid) DeGrado-Warren et al. (2008) pubmed:18330356|imex:IM-8752 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15690153|dip:DIP-58826E|imex:IM-8752-62 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001395.1|refseq:NP_001230538.1|refseq:NP_001230539.1|refseq:NP_061110.2|refseq:NP_001230540.1|ensembl:ENSG00000048540(gene)|ensembl:ENST00000320122(transcript)|ensembl:ENST00000354662(transcript)|ensembl:ENST00000441439(transcript)|ensembl:ENST00000447609(transcript)|ensembl:ENST00000534946(transcript)|ensembl:ENST00000535535(transcript)|ensembl:ENST00000537304(transcript)|ensembl:ENST00000540848(transcript)|ensembl:ENST00000541846(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0035360"(positive regulation of peroxisome proliferator activated receptor signaling pathway)|go:"GO:0045600"(positive regulation of fat cell differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:2000324"(positive regulation of glucocorticoid receptor signaling pathway)|interpro:IPR001781(Zinc finger, LIM-type)|refseq:XP_011519064.1|refseq:XP_011519065.1|refseq:NP_001230542.1|refseq:NP_001230541.1|refseq:XP_006719173.1|refseq:XP_006719174.1|dip:DIP-50129N refseq:NP_001124306.1|refseq:NP_001281.1|dip:DIP-24262N|dip:DIP-41215N|ensembl:ENSG00000169744(gene)|ensembl:ENST00000304523(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001942"(hair follicle development)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005886"(plasma membrane)|go:"GO:0007399"(nervous system development)|go:"GO:0010669"(epithelial structure maintenance)|go:"GO:0019899"(enzyme binding)|go:"GO:0030274"(LIM domain binding)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031252"(cell leading edge)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0043549"(regulation of kinase activity)|go:"GO:0044089"(positive regulation of cellular component biogenesis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|interpro:IPR029005|interpro:IPR030174|interpro:IPR041363 psi-mi:"MI:0465"(dip) crc64:05284546BA5EC226 crc64:E86387BA027F383A full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/05 2017/08/10 rogid:cZJuQ9JWbTbuABfiuU3iIRoMWhc9606 rogid:3p/spcR1ariBlpLJczJxP5Mfi9w9606 rigid:AlQejbNvt3mQ+ItvtVttm9MLrn0 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q15019 uniprotkb:Q99719 intact:EBI-741220|intact:EBI-28986019|ensembl:ENSP00000353157|ensembl:ENSP00000375832|ensembl:ENSP00000375834|ensembl:ENSP00000385172|uniprotkb:Q14132|uniprotkb:Q8IUK9|uniprotkb:Q96CB0|uniprotkb:B4DGE8|uniprotkb:Q53QU3 intact:EBI-373345|uniprotkb:O15251|uniprotkb:Q96MY5|ensembl:ENSP00000391311 psi-mi:sept2_human(display_long)|uniprotkb:SEPTIN2(gene name)|psi-mi:SEPTIN2(display_short)|uniprotkb:DIFF6(gene name synonym)|uniprotkb:KIAA0158(gene name synonym)|uniprotkb:NEDD5(gene name synonym)|uniprotkb:Neural precursor cell expressed developmentally down-regulated protein 5(gene name synonym)|uniprotkb:SEPT2(gene name synonym) psi-mi:sept5_human(display_long)|uniprotkb:SEPTIN5(gene name)|psi-mi:SEPTIN5(display_short)|uniprotkb:Cell division control-related protein 1(gene name synonym)|uniprotkb:PNUTL1(gene name synonym)|uniprotkb:Peanut-like protein 1(gene name synonym)|uniprotkb:SEPT5(gene name synonym) psi-mi:"MI:0018"(two hybrid) DeGrado-Warren et al. (2008) pubmed:18330356|imex:IM-8752 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15690137|dip:DIP-58840E|imex:IM-8752-82 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001269901.1|refseq:NP_001269902.1|ensembl:ENSG00000168385(gene)|ensembl:ENST00000360051(transcript)|ensembl:ENST00000391971(transcript)|ensembl:ENST00000391973(transcript)|ensembl:ENST00000402092(transcript)|go:"GO:0000145"(exocyst)|go:"GO:0000776"(kinetochore)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005819"(spindle)|go:"GO:0005886"(plasma membrane)|go:"GO:0005930"(axoneme)|go:"GO:0005940"(septin ring)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0017157"(regulation of exocytosis)|go:"GO:0030496"(midbody)|go:"GO:0031105"(septin complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0032153"(cell division site)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0034613"(cellular protein localization)|go:"GO:0042802"(identical protein binding)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045296"(cadherin binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060170"(ciliary membrane)|go:"GO:0060271"(cilium assembly)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097227"(sperm annulus)|go:"GO:0097730"(non-motile cilium)|interpro:IPR008113(Septin 2)|interpro:IPR016491(Septin)|interpro:IPR027417|interpro:IPR030379|mint:Q15019|rcsb pdb:2QA5|rcsb pdb:2QAG|rcsb pdb:2QNR|rcsb pdb:6UPA|rcsb pdb:6UPQ|rcsb pdb:6UPR|reactome:R-HSA-5620912|refseq:NP_001008491.1|refseq:NP_001008492.1|refseq:NP_004395.1|refseq:NP_006146.1|refseq:XP_016859694.1|refseq:XP_016859695.1|refseq:NP_001307958.1|refseq:NP_001307959.1|refseq:NP_001307960.1|refseq:NP_001307961.1|refseq:NP_001307962.1|refseq:NP_001307963.1|refseq:NP_001307964.1|ensembl:ENSP00000353157|ensembl:ENSP00000375832|ensembl:ENSP00000375834|ensembl:ENST00000401990|ensembl:ENSP00000385109|ensembl:ENSP00000385172|ensembl:ENST00000616972|ensembl:ENSP00000479861|dip:DIP-38220N refseq:NP_002679.2|refseq:NP_001009939.1|ensembl:ENSG00000184702(gene)|ensembl:ENST00000455784(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005940"(septin ring)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016080"(synaptic vesicle targeting)|go:"GO:0017157"(regulation of exocytosis)|go:"GO:0030534"(adult behavior)|go:"GO:0031105"(septin complex)|go:"GO:0032153"(cell division site)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035176"(social behavior)|go:"GO:0042802"(identical protein binding)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|interpro:IPR016491(Septin)|interpro:IPR027417|interpro:IPR030379|interpro:IPR030647|mint:Q99719|rcsb pdb:6WCU|dip:DIP-31201N psi-mi:"MI:0465"(dip) crc64:12CCBBE30806F92F crc64:47054765DEA10D33 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/05 2017/08/10 rogid:H0Us8GtPe2XuXlOYXC0DX79kB/49606 rogid:kubhD1O+WmJeDWTlX+rcjpP9yRc9606 rigid:QnONYnZZYVrSjtnt59VxGN18DwI false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q04206 uniprotkb:P47712 intact:EBI-73886|ensembl:ENSP00000384273|uniprotkb:Q6GTV1|uniprotkb:Q6SLK1 intact:EBI-1044090|uniprotkb:Q29R80|ensembl:ENSP00000356436|uniprotkb:B1AKG4 psi-mi:tf65_human(display_long)|uniprotkb:Nuclear factor NF-kappa-B p65 subunit(gene name synonym)|uniprotkb:RELA(gene name)|psi-mi:RELA(display_short)|uniprotkb:NFKB3(gene name synonym)|uniprotkb:Nuclear factor of kappa light polypeptide gene enhancer in B-cells 3(gene name synonym) psi-mi:pa24a_human(display_long)|uniprotkb:PLA2G4A(gene name)|psi-mi:PLA2G4A(display_short)|uniprotkb:CPLA2(gene name synonym)|uniprotkb:PLA2G4(gene name synonym)|uniprotkb:Phospholipase A2 group IVA(gene name synonym) psi-mi:"MI:0018"(two hybrid) DeGrado-Warren et al. (2008) pubmed:18330356|imex:IM-8752 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15690169|dip:DIP-88120E|imex:IM-8752-162 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000173039(gene)|ensembl:ENST00000406246(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|refseq:NP_001138610.1|refseq:NP_068810.3|refseq:NP_001230913.1|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0070301"(cellular response to hydrogen peroxide)|dip:DIP-24238N|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001889"(liver development)|go:"GO:0001942"(hair follicle development)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006117"(acetaldehyde metabolic process)|go:"GO:0006325"(chromatin organization)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006954"(inflammatory response)|go:"GO:0006968"(cellular defense response)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0007568"(aging)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0010033"(response to organic substance)|go:"GO:0010224"(response to UV-B)|go:"GO:0014040"(positive regulation of Schwann cell differentiation)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032495"(response to muramyl dipeptide)|go:"GO:0032570"(response to progesterone)|go:"GO:0032735"(positive regulation of interleukin-12 production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032868"(response to insulin)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0033234"(negative regulation of protein sumoylation)|go:"GO:0033590"(response to cobalamin)|go:"GO:0034097"(response to cytokine)|go:"GO:0035525"(NF-kappaB p50/p65 complex)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0035924"(cellular response to vascular endothelial growth factor stimulus)|go:"GO:0035994"(response to muscle stretch)|go:"GO:0038061"(NIK/NF-kappaB signaling)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0042277"(peptide binding)|go:"GO:0042301"(phosphate ion binding)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042805"(actinin binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043200"(response to amino acid)|go:"GO:0043278"(response to morphine)|go:"GO:0043620"(regulation of DNA-templated transcription in response to stress)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0050862"(positive regulation of T cell receptor signaling pathway)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051591"(response to cAMP)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0051607"(defense response to virus)|go:"GO:0070431"(nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:"GO:0070498"(interleukin-1-mediated signaling pathway)|go:"GO:0070555"(response to interleukin-1)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071223"(cellular response to lipoteichoic acid)|go:"GO:0071224"(cellular response to peptidoglycan)|go:"GO:0071316"(cellular response to nicotine)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0071354"(cellular response to interleukin-6)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071532"(ankyrin repeat binding)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099527"(postsynapse to nucleus signaling pathway)|go:"GO:0140296"(general transcription initiation factor binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1901222"(regulation of NIK/NF-kappaB signaling)|go:"GO:1901223"(negative regulation of NIK/NF-kappaB signaling)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1901522"(positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus)|go:"GO:1902004"(positive regulation of amyloid-beta formation)|go:"GO:1902894"(negative regulation of miRNA transcription)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1904385"(cellular response to angiotensin)|go:"GO:1904996"(positive regulation of leukocyte adhesion to vascular endothelial cell)|go:"GO:2000630"(positive regulation of miRNA metabolic process)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR000451(NF-kappa-B/Rel/dorsal)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011539(Rel homology)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR030492|interpro:IPR030495|interpro:IPR032397|interpro:IPR033926|interpro:IPR037059|mint:Q04206|rcsb pdb:1NFI|rcsb pdb:2LSP|rcsb pdb:2O61|rcsb pdb:3GUT|rcsb pdb:3QXY|rcsb pdb:3RC0|rcsb pdb:4KV1|rcsb pdb:4KV4|rcsb pdb:5U4K|rcsb pdb:5URN|rcsb pdb:6NV2|rcsb pdb:6QHL|rcsb pdb:6QHM|rcsb pdb:6YOW|rcsb pdb:6YOX|rcsb pdb:6YOY|rcsb pdb:6YP2|rcsb pdb:6YP3|rcsb pdb:6YP8|rcsb pdb:6YPL|rcsb pdb:6YPY|rcsb pdb:6YQ2|rcsb pdb:7BI3|rcsb pdb:7BIQ|rcsb pdb:7BIY|rcsb pdb:7BJF|rcsb pdb:7BJL|rcsb pdb:7BJW|rcsb pdb:7BKH|rcsb pdb:7NJ9|rcsb pdb:7NJB|rcsb pdb:7NK3|rcsb pdb:7NK5|rcsb pdb:7NLA|rcsb pdb:7NLE|rcsb pdb:7NM1|rcsb pdb:7NM3|rcsb pdb:7NM9|rcsb pdb:7NQP|rcsb pdb:7NR7|rcsb pdb:7NSV|rcsb pdb:7NV4|rcsb pdb:7NVI|rcsb pdb:7NWS|rcsb pdb:7NXS|rcsb pdb:7NXT|rcsb pdb:7NXW|rcsb pdb:7NXY|rcsb pdb:7NY4|rcsb pdb:7NYE|rcsb pdb:7NYF|rcsb pdb:7NYG|rcsb pdb:7NZ6|rcsb pdb:7NZG|rcsb pdb:7NZK|rcsb pdb:7NZV|rcsb pdb:7O34|rcsb pdb:7O3A|rcsb pdb:7O3F|rcsb pdb:7O3P|rcsb pdb:7O3Q|rcsb pdb:7O3R|rcsb pdb:7O3S|rcsb pdb:7O57|rcsb pdb:7O59|rcsb pdb:7O5A|rcsb pdb:7O5C|rcsb pdb:7O5D|rcsb pdb:7O5F|rcsb pdb:7O5G|rcsb pdb:7O5O|rcsb pdb:7O5P|rcsb pdb:7O5S|rcsb pdb:7O5U|rcsb pdb:7O5X|rcsb pdb:7O6F|rcsb pdb:7O6G|rcsb pdb:7O6I|rcsb pdb:7O6J|rcsb pdb:7O6K|rcsb pdb:7O6M|rcsb pdb:7O6O|reactome:R-HSA-1169091|reactome:R-HSA-1810476|reactome:R-HSA-193692|reactome:R-HSA-202424|reactome:R-HSA-209560|reactome:R-HSA-2559582|reactome:R-HSA-2871837|reactome:R-HSA-3134963|reactome:R-HSA-3214841|reactome:R-HSA-381340|reactome:R-HSA-445989|reactome:R-HSA-448706|reactome:R-HSA-4755510|reactome:R-HSA-5603029|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5621575|reactome:R-HSA-5660668|reactome:R-HSA-844456|reactome:R-HSA-8853884|reactome:R-HSA-9020702|reactome:R-HSA-933542|reactome:R-HSA-9660826 refseq:NP_077734.1|go:"GO:0102567"|go:"GO:0102568"|go:"GO:1902387"(ceramide 1-phosphate binding)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR002642(Lysophospholipase, catalytic region)|interpro:IPR016035(Acyl transferase/acyl hydrolase/lysophospholipase)|interpro:IPR035892|interpro:IPR041847|rcsb pdb:1BCI|rcsb pdb:1CJY|rcsb pdb:1RLW|reactome:R-HSA-111995|reactome:R-HSA-1482788|reactome:R-HSA-1482798|reactome:R-HSA-1482801|reactome:R-HSA-1482839|reactome:R-HSA-1482922|reactome:R-HSA-1482925|reactome:R-HSA-1483115|reactome:R-HSA-1483166|reactome:R-HSA-2142753|reactome:R-HSA-418592|reactome:R-HSA-432142|reactome:R-HSA-6811436|ensembl:ENSG00000116711(gene)|ensembl:ENST00000367466(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001516"(prostaglandin biosynthetic process)|go:"GO:0002827"(positive regulation of T-helper 1 type immune response)|go:"GO:0004622"(lysophospholipase activity)|go:"GO:0004623"(phospholipase A2 activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006071"(glycerol metabolic process)|go:"GO:0006640"(monoacylglycerol biosynthetic process)|go:"GO:0006663"(platelet activating factor biosynthetic process)|go:"GO:0008374"(O-acyltransferase activity)|go:"GO:0010314"(phosphatidylinositol-5-phosphate binding)|go:"GO:0010572"(positive regulation of platelet activation)|go:"GO:0019369"(arachidonic acid metabolic process)|go:"GO:0019370"(leukotriene biosynthetic process)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0032308"(positive regulation of prostaglandin secretion)|go:"GO:0034478"(phosphatidylglycerol catabolic process)|go:"GO:0034638"(phosphatidylcholine catabolic process)|go:"GO:0036151"(phosphatidylcholine acyl-chain remodeling)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043032"(positive regulation of macrophage activation)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046475"(glycerophospholipid catabolic process)|go:"GO:0047498"(calcium-dependent phospholipase A2 activity)|go:"GO:0047499"(calcium-independent phospholipase A2 activity)|go:"GO:0050482"(arachidonic acid secretion)|go:"GO:0070273"(phosphatidylinositol-4-phosphate binding)|go:"GO:0071236"(cellular response to antibiotic)|go:"GO:0102545"(phosphatidyl phospholipase B activity)|go:"GO:0006690"(icosanoid metabolic process)|refseq:NP_001298122.1|refseq:XP_011507944.1|dip:DIP-40991N psi-mi:"MI:0465"(dip) - crc64:EE71CA0EBE617856 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/05 2017/08/10 rogid:w/ClZ7PzdLH1LLxTGrk22KUz8V49606 rogid:D/yM7EFWP6xaMQ//7wutJS5D3jw9606 rigid:nJ9wyjPmceTE1CprF0m56nxGcpc false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P62195 uniprotkb:Q96EK4 intact:EBI-357745|uniprotkb:O35051|uniprotkb:O43208|uniprotkb:P52915|uniprotkb:P47210|uniprotkb:P52916|uniprotkb:A8K763|uniprotkb:A8K3Z3|ensembl:ENSP00000310572 intact:EBI-1790529|uniprotkb:O94795|uniprotkb:A8K002|uniprotkb:A4UCT5|ensembl:ENSP00000304689 psi-mi:prs8_human(display_long)|uniprotkb:PSMC5(gene name)|psi-mi:PSMC5(display_short)|uniprotkb:SUG1(gene name synonym)|uniprotkb:Proteasome 26S subunit ATPase 5(gene name synonym)|uniprotkb:Proteasome subunit p45(gene name synonym)|uniprotkb:p45/SUG(gene name synonym)|uniprotkb:Thyroid hormone receptor-interacting protein 1(gene name synonym)|uniprotkb:26S proteasome AAA-ATPase subunit RPT6(gene name synonym) psi-mi:tha11_human(display_long)|uniprotkb:THAP11(gene name)|psi-mi:THAP11(display_short)|uniprotkb:HRIHFB2206(orf name) psi-mi:"MI:0018"(two hybrid) DeGrado-Warren et al. (2008) pubmed:18330356|imex:IM-8752 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15690185|dip:DIP-58852E|imex:IM-8752-64 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001186092.1|refseq:NP_002796.4|reactome:R-HSA-195253|ensembl:ENSG00000087191(gene)|ensembl:ENST00000310144(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0016020"(membrane)|go:"GO:0016234"(inclusion body)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0022624"(proteasome accessory complex)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031531"(thyrotropin-releasing hormone receptor binding)|go:"GO:0031595"(nuclear proteasome complex)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0043069"(negative regulation of programmed cell death)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|go:"GO:0090261"(positive regulation of inclusion body assembly)|go:"GO:0098794"(postsynapse)|go:"GO:0140296"(general transcription initiation factor binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1901800"(positive regulation of proteasomal protein catabolic process)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR032501|interpro:IPR041569|mint:P62195|rcsb pdb:2KRK|rcsb pdb:3KW6|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:5VGZ|rcsb pdb:5VHF|rcsb pdb:5VHH|rcsb pdb:5VHI|rcsb pdb:5VHJ|rcsb pdb:5VHM|rcsb pdb:5VHN|rcsb pdb:5VHO|rcsb pdb:5VHP|rcsb pdb:5VHQ|rcsb pdb:5VHR|rcsb pdb:5VHS|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6WJD|rcsb pdb:6WJN|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|dip:DIP-36645N refseq:NP_065190.2|dip:DIP-46732N|ensembl:ENSP00000304689|ensembl:ENSG00000168286(gene)|ensembl:ENST00000303596(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|interpro:IPR006612(Zinc finger, C2CH-type)|rcsb pdb:2LAU|rcsb pdb:5AJS psi-mi:"MI:0465"(dip) crc64:29C6410C4A85A7F7 crc64:25235D20CB54D8C2 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/05 2017/08/10 rogid:zgUTOX/O4m86U/Nf+pnT7u0m0gY9606 rogid:qzl6RN2xlTuDBruwyKLyDTNRCKE9606 rigid:Nhlfncs0FVN2jgMAyB4S6FVe/jw false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P43355 uniprotkb:O00429 intact:EBI-740978|ensembl:ENSP00000349085|uniprotkb:O00346|uniprotkb:B2RC81 intact:EBI-724571|uniprotkb:O14541|uniprotkb:O60709|uniprotkb:Q7L6B3|uniprotkb:Q8TBT7|uniprotkb:Q9BWM1|uniprotkb:Q9Y5J2|uniprotkb:B4DSU8|uniprotkb:A8K4X9|ensembl:ENSP00000450399|uniprotkb:B4DGC9|uniprotkb:J3KPI2|uniprotkb:Q59GN9|uniprotkb:G8JLD5 psi-mi:maga1_human(display_long)|uniprotkb:MAGE-1 antigen(gene name synonym)|uniprotkb:Antigen MZ2-E(gene name synonym)|uniprotkb:Cancer/testis antigen 1.1(gene name synonym)|uniprotkb:MAGEA1(gene name)|psi-mi:MAGEA1(display_short)|uniprotkb:MAGE1(gene name synonym)|uniprotkb:MAGE1A(gene name synonym) psi-mi:dnm1l_human(display_long)|uniprotkb:Dynamin-like protein(gene name synonym)|uniprotkb:Dnm1p/Vps1p-like protein(gene name synonym)|uniprotkb:Dynamin family member proline-rich carboxyl-terminal domain less(gene name synonym)|uniprotkb:Dynamin-related protein 1(gene name synonym)|uniprotkb:Dynamin-like protein 4(gene name synonym)|uniprotkb:Dynamin-like protein IV(gene name synonym)|uniprotkb:DNM1L(gene name)|psi-mi:DNM1L(display_short)|uniprotkb:DLP1(gene name synonym)|uniprotkb:DRP1(gene name synonym) psi-mi:"MI:0018"(two hybrid) DeGrado-Warren et al. (2008) pubmed:18330356|imex:IM-8752 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15690201|dip:DIP-58820E|imex:IM-8752-84 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004979.3|ensembl:ENSG00000198681(gene)|ensembl:ENST00000356661(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|interpro:IPR002190(MAGE protein)|interpro:IPR021072|interpro:IPR030093|interpro:IPR037445|interpro:IPR041898|interpro:IPR041899|rcsb pdb:1W72|rcsb pdb:3BO8|dip:DIP-54794N refseq:NP_005681.2|refseq:NP_036192.2|refseq:NP_036193.2|ensembl:ENSG00000087470(gene)|ensembl:ENST00000549701(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000266"(mitochondrial fission)|go:"GO:0001836"(release of cytochrome c from mitochondria)|go:"GO:0003374"(dynamin family protein polymerization involved in mitochondrial fission)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005777"(peroxisome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005903"(brush border)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0008017"(microtubule binding)|go:"GO:0008289"(lipid binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010637"(negative regulation of mitochondrial fusion)|go:"GO:0010821"(regulation of mitochondrion organization)|go:"GO:0016020"(membrane)|go:"GO:0016559"(peroxisome fission)|go:"GO:0030276"(clathrin binding)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0030742"(GTP-dependent protein binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0036466"(synaptic vesicle recycling via endosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043653"(mitochondrial fragmentation involved in apoptotic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0048312"(intracellular distribution of mitochondria)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0048511"(rhythmic process)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0051433"(BH2 domain binding)|go:"GO:0060047"(heart contraction)|go:"GO:0061003"(positive regulation of dendritic spine morphogenesis)|go:"GO:0061025"(membrane fusion)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070266"(necroptotic process)|go:"GO:0070584"(mitochondrion morphogenesis)|go:"GO:0070585"(protein localization to mitochondrion)|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:0090141"(positive regulation of mitochondrial fission)|go:"GO:0090149"(mitochondrial membrane fission)|go:"GO:0090200"(positive regulation of release of cytochrome c from mitochondria)|go:"GO:0090650"(cellular response to oxygen-glucose deprivation)|go:"GO:1900244"(positive regulation of synaptic vesicle endocytosis)|go:"GO:1903146"(regulation of autophagy of mitochondrion)|go:"GO:1903578"(regulation of ATP metabolic process)|go:"GO:1904579"(cellular response to thapsigargin)|go:"GO:1904666"(regulation of ubiquitin protein ligase activity)|go:"GO:1905395"(response to flavonoid)|go:"GO:1990910"(response to hypobaric hypoxia)|go:"GO:2000302"(positive regulation of synaptic vesicle exocytosis)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR000375(Dynamin central region)|interpro:IPR001401(Dynamin, GTPase region)|interpro:IPR003130(Dynamin GTPase effector)|interpro:IPR019762|interpro:IPR020850|interpro:IPR022812|interpro:IPR027417|interpro:IPR030381|interpro:IPR030556|mint:O00429|rcsb pdb:3W6N|rcsb pdb:3W6O|rcsb pdb:3W6P|rcsb pdb:4BEJ|rcsb pdb:4H1U|rcsb pdb:4H1V|rcsb pdb:5WP9|go:"GO:0098835"(presynaptic endocytic zone membrane)|go:"GO:1900063"(regulation of peroxisome organization)|reactome:R-HSA-75153|refseq:NP_001265392.1|refseq:NP_001265393.1|refseq:NP_001265394.1|refseq:NP_001265395.1|refseq:NP_001317309.1|dip:DIP-42704N psi-mi:"MI:0465"(dip) crc64:544EEB1F9F4E9D33 crc64:F9521A376B785B71 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/05 2017/08/10 rogid:6XW3mnTNM3yvOtXmiFbU8Uz3hjA9606 rogid:hmh7m80FPMdx6/3eUY6l0IK/AqY9606 rigid:TG6srazh8XY8aGSJM/T+wXQ6nRw false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q86SX3 uniprotkb:P35638 intact:EBI-3247115|ensembl:ENSP00000376308|uniprotkb:Q86TT5|uniprotkb:Q9H7H4|uniprotkb:Q86TT3|uniprotkb:Q96B41|uniprotkb:B5MDG3|uniprotkb:Q86TT4|uniprotkb:E9PAQ4 intact:EBI-742651|ensembl:ENSP00000340671|ensembl:ENSP00000447188|ensembl:ENSP00000494844|uniprotkb:F8VS99 psi-mi:tedc1_human(display_long)|uniprotkb:TEDC1(gene name)|psi-mi:TEDC1(display_short)|uniprotkb:C14orf80(gene name synonym) psi-mi:ddit3_human(display_long)|uniprotkb:CHOP10(gene name synonym)|uniprotkb:C/EBP-homologous protein(gene name synonym)|uniprotkb:DDIT3(gene name)|psi-mi:DDIT3(display_short)|uniprotkb:CHOP(gene name synonym)|uniprotkb:GADD153(gene name synonym)|uniprotkb:Growth arrest and DNA damage-inducible protein GADD153(gene name synonym)|uniprotkb:C/EBP-homologous protein 10(gene name synonym)|uniprotkb:C/EBP zeta(gene name synonym)|uniprotkb:CCAAT/enhancer-binding protein homologous protein(gene name synonym) psi-mi:"MI:0018"(two hybrid) DeGrado-Warren et al. (2008) pubmed:18330356|imex:IM-8752 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15690217|dip:DIP-58818E|imex:IM-8752-122 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001128347.1|ensembl:ENSG00000185347(gene)|ensembl:ENST00000392523(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005814"(centriole)|go:"GO:0005929"(cilium)|go:"GO:0045880"(positive regulation of smoothened signaling pathway)|interpro:IPR028100|interpro:IPR043535|interpro:IPR027996|refseq:NP_001128348.1|refseq:NP_001185912.1|refseq:NP_001128349.1|dip:DIP-62062N refseq:NP_001181986.1|refseq:NP_004074.2|refseq:NP_001181982.1|refseq:NP_001181983.1|refseq:NP_001181984.1|ensembl:ENSG00000175197(gene)|go:"GO:0001955"(blood vessel maturation)|ensembl:ENST00000346473(transcript)|ensembl:ENST00000547303(transcript)|ensembl:ENST00000623876(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003677"(DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032792"(negative regulation of CREB transcription factor activity)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0036488"(CHOP-C/EBP complex)|go:"GO:0036499"(PERK-mediated unfolded protein response)|go:"GO:0036500"(ATF6-mediated unfolded protein response)|go:"GO:0042594"(response to starvation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043522"(leucine zipper domain binding)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0032713"(negative regulation of interleukin-4 production)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0006983"(ER overload response)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0007049"(cell cycle)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008140"(cAMP response element binding protein binding)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0005737"(cytoplasm)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0005770"(late endosome)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032689"(negative regulation of interferon-gamma production)|go:"GO:0032700"(negative regulation of interleukin-17 production)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0051209"(release of sequestered calcium ion into cytosol)|go:"GO:0051898"(negative regulation of protein kinase B signaling)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0072655"(establishment of protein localization to mitochondrion)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0120163"(negative regulation of cold-induced thermogenesis)|go:"GO:0140416"(transcription regulator inhibitor activity)|go:"GO:1902237"(positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903026"(negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990442"(intrinsic apoptotic signaling pathway in response to nitrosative stress)|go:"GO:1990617"(CHOP-ATF4 complex)|go:"GO:1990622"(CHOP-ATF3 complex)|go:"GO:2000016"(negative regulation of determination of dorsal identity)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR016670(DNA damage-inducible transcript 3)|mint:P35638|reactome:R-HSA-380994|reactome:R-HSA-381183|reactome:R-HSA-9614657|reactome:R-HSA-9633012|reactome:R-HSA-9648895|go:"GO:0043618"(regulation of transcription from RNA polymerase II promoter in response to stress)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045662"(negative regulation of myoblast differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|dip:DIP-41589N psi-mi:"MI:0465"(dip) crc64:3E34FACE82E0EACF crc64:31905293FB1FBBE2 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/05 2017/08/10 rogid:TEv3WjggyWs0uRE4CRaeSB7Wmfk9606 rogid:xyMsMwPwid+S2IYb3H0K0pnUc309606 rigid:gfQU2Pf6gRlNIUk3pdEDHHZsaOM false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P28676 uniprotkb:P30626 intact:EBI-947242|uniprotkb:Q53TB5|uniprotkb:Q59EP3|uniprotkb:B2R5X3|ensembl:ENSP00000394842 intact:EBI-750459|uniprotkb:D6W5Q0|intact:EBI-2623494|uniprotkb:A8MTH6|uniprotkb:B4DKK2|ensembl:ENSP00000265729 psi-mi:gran_human(display_long)|uniprotkb:GCA(gene name)|psi-mi:GCA(display_short)|uniprotkb:GCL(gene name synonym) psi-mi:sorcn_human(display_long)|uniprotkb:22 kDa protein(gene name synonym)|uniprotkb:CP-22(gene name synonym)|uniprotkb:V19(gene name synonym)|uniprotkb:SRI(gene name)|psi-mi:SRI(display_short) psi-mi:"MI:0018"(two hybrid) DeGrado-Warren et al. (2008) pubmed:18330356|imex:IM-8752 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15690233|dip:DIP-58846E|imex:IM-8752-102 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_036330.1|dip:DIP-41437N|ensembl:ENSG00000115271(gene)|ensembl:ENST00000437150(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0061025"(membrane fusion)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|rcsb pdb:1F4O|rcsb pdb:1F4Q|rcsb pdb:1K94|rcsb pdb:1K95|reactome:R-HSA-6798695 refseq:NP_944490.1|refseq:NP_003121.1|refseq:NP_001243820.1|refseq:NP_001243821.1|dip:DIP-40970N|ensembl:ENSG00000075142(gene)|ensembl:ENST00000265729(transcript)|go:"GO:0001508"(action potential)|go:"GO:0002020"(protease binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006880"(intracellular sequestering of iron ion)|go:"GO:0006942"(regulation of striated muscle contraction)|go:"GO:0007165"(signal transduction)|go:"GO:0007507"(heart development)|go:"GO:0007517"(muscle organ development)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0010459"(negative regulation of heart rate)|go:"GO:0030315"(T-tubule)|go:"GO:0033017"(sarcoplasmic reticulum membrane)|go:"GO:0035774"(positive regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0042802"(identical protein binding)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0043679"(axon terminus)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044326"(dendritic spine neck)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051281"(positive regulation of release of sequestered calcium ion into cytosol)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0055118"(negative regulation of cardiac muscle contraction)|go:"GO:0060315"(negative regulation of ryanodine-sensitive calcium-release channel activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0086004"(regulation of cardiac muscle cell contraction)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1901077"(regulation of relaxation of muscle)|go:"GO:1901841"(regulation of high voltage-gated calcium channel activity)|go:"GO:0010649"(regulation of cell communication by electrical coupling)|go:"GO:0010880"(regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0016020"(membrane)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0030018"(Z disc)|rcsb pdb:2JC2|rcsb pdb:4U8D|rcsb pdb:4UPG|rcsb pdb:4USL|rcsb pdb:5MRA|reactome:R-HSA-2672351|reactome:R-HSA-418359|reactome:R-HSA-425561|reactome:R-HSA-5578775|reactome:R-HSA-936837|go:"GO:1901844"(regulation of cell communication by electrical coupling involved in cardiac conduction)|go:"GO:2000678"(negative regulation of transcription regulatory region DNA binding)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|mint:P30626|rcsb pdb:1JUO psi-mi:"MI:0465"(dip) crc64:88CA4DDF835AFFE4 crc64:A4829C7650A5E3FA full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/05 2017/08/10 rogid:I1zdQPwDUFrBGazaVREgC7nqxok9606 rogid:upE31IMimaotkgnYa7HYr7EYAxc9606 rigid:P3biU8Zjfa5ii/gfjl2Oa0CvL2Q false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P12955 uniprotkb:Q93009 intact:EBI-948765|ensembl:ENSP00000244137|uniprotkb:Q8TBN9|uniprotkb:Q9BT75|uniprotkb:A8K3Z1|uniprotkb:A8K416|uniprotkb:A8K696|uniprotkb:A8MX47|uniprotkb:B4DGJ1|uniprotkb:B4DDB7|uniprotkb:E9PCE8 intact:EBI-302474|uniprotkb:A6NMY8|intact:EBI-28988230|ensembl:ENSP00000343535|uniprotkb:B7Z815|uniprotkb:H0Y3G8 psi-mi:pepd_human(display_long)|uniprotkb:Proline dipeptidase(gene name synonym)|uniprotkb:Imidodipeptidase(gene name synonym)|uniprotkb:Peptidase D(gene name synonym)|uniprotkb:PEPD(gene name)|psi-mi:PEPD(display_short)|uniprotkb:PRD(gene name synonym) psi-mi:ubp7_human(display_long)|uniprotkb:USP7(gene name)|psi-mi:USP7(display_short)|uniprotkb:HAUSP(gene name synonym)|uniprotkb:Ubiquitin thioesterase 7(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease 7(gene name synonym)|uniprotkb:Deubiquitinating enzyme 7(gene name synonym)|uniprotkb:Herpesvirus-associated ubiquitin-specific protease(gene name synonym) psi-mi:"MI:0018"(two hybrid) DeGrado-Warren et al. (2008) pubmed:18330356|imex:IM-8752 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15690265|dip:DIP-88121E|imex:IM-8752-104 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) dip:DIP-50038N|ensembl:ENSG00000124299(gene)|ensembl:ENST00000244137(transcript)|go:"GO:0004181"(metallocarboxypeptidase activity)|go:"GO:0006508"(proteolysis)|go:"GO:0006520"(cellular amino acid metabolic process)|go:"GO:0008233"(peptidase activity)|go:"GO:0030145"(manganese ion binding)|go:"GO:0030574"(collagen catabolic process)|go:"GO:0070006"(metalloaminopeptidase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0102009"(proline dipeptidase activity)|interpro:IPR000994(Peptidase M24, catalytic core)|interpro:IPR001131(Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site)|interpro:IPR007865(Peptidase M24B, X-Pro dipeptidase/aminopeptidase P N-terminal)|interpro:IPR029149|interpro:IPR036005|rcsb pdb:2IW2|rcsb pdb:2OKN|rcsb pdb:5M4G|rcsb pdb:5M4J|rcsb pdb:5M4L|rcsb pdb:5M4Q|rcsb pdb:5MBY|rcsb pdb:5MBZ|rcsb pdb:5MC0|rcsb pdb:5MC1|rcsb pdb:5MC2|rcsb pdb:5MC3|rcsb pdb:5MC4|rcsb pdb:5MC5|rcsb pdb:6H2P|rcsb pdb:6H2Q|rcsb pdb:6QSB|rcsb pdb:6QSC|rcsb pdb:6SRE|rcsb pdb:6SRF|rcsb pdb:6SRG|refseq:NP_000276.2|refseq:NP_001159529.1|refseq:NP_001159528.1 rcsb pdb:4PYZ|rcsb pdb:4WPH|rcsb pdb:4WPI|rcsb pdb:4YOC|rcsb pdb:4YSI|rcsb pdb:4Z96|rcsb pdb:4Z97|rcsb pdb:5C56|rcsb pdb:5C6D|rcsb pdb:5FWI|rcsb pdb:5GG4|rcsb pdb:5J7T|rcsb pdb:5JTJ|rcsb pdb:5JTV|rcsb pdb:5KYB|rcsb pdb:4M5X|rcsb pdb:5KYC|rcsb pdb:5KYD|rcsb pdb:5KYE|rcsb pdb:5KYF|interpro:IPR029346|interpro:IPR038765|mint:Q93009|rcsb pdb:1NB8|rcsb pdb:1NBF|rcsb pdb:1YY6|rcsb pdb:1YZE|rcsb pdb:2F1W|rcsb pdb:2F1X|rcsb pdb:2F1Y|rcsb pdb:2F1Z|rcsb pdb:2FOJ|rcsb pdb:2FOO|rcsb pdb:2FOP|rcsb pdb:2KVR|rcsb pdb:2XXN|rcsb pdb:2YLM|rcsb pdb:3MQR|rcsb pdb:3MQS|rcsb pdb:4JJQ|rcsb pdb:4KG9|rcsb pdb:4M5W|go:"GO:0006283"(transcription-coupled nucleotide-excision repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010216"(maintenance of DNA methylation)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035520"(monoubiquitinated protein deubiquitination)|go:"GO:0035616"(histone H2B conserved C-terminal lysine deubiquitination)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0048511"(rhythmic process)|go:"GO:0050821"(protein stabilization)|go:"GO:0051090"(regulation of DNA-binding transcription factor activity)|go:"GO:0070536"(protein K63-linked deubiquitination)|go:"GO:0101005"(deubiquitinase activity)|go:"GO:1901537"(positive regulation of DNA demethylation)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|go:"GO:1904353"(regulation of telomere capping)|go:"GO:1905279"(regulation of retrograde transport, endosome to Golgi)|go:"GO:1990380"(Lys48-specific deubiquitinase activity)|interpro:IPR001394(Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)|interpro:IPR002083(MATH)|interpro:IPR008974(TRAF-like)|interpro:IPR018200|interpro:IPR024729|interpro:IPR028889|ensembl:ENSG00000187555(gene)|ensembl:ENST00000344836(transcript)|go:"GO:0002039"(p53 binding)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0006111"(regulation of gluconeogenesis)|rcsb pdb:5N9R|rcsb pdb:5N9T|rcsb pdb:5NGE|rcsb pdb:5NGF|rcsb pdb:5UQV|rcsb pdb:5UQX|rcsb pdb:5VS6|rcsb pdb:5VSB|rcsb pdb:5VSK|rcsb pdb:5WHC|rcsb pdb:6F5H|rcsb pdb:6M1K|rcsb pdb:6P5L|rcsb pdb:6VN2|rcsb pdb:6VN3|rcsb pdb:6VN4|rcsb pdb:6VN5|rcsb pdb:6VN6|rcsb pdb:7CM2|reactome:R-HSA-5689880|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6804757|reactome:R-HSA-8866652|reactome:R-HSA-8948747|refseq:NP_001273386.1|refseq:NP_003461.2|refseq:NP_001308787.1|ensembl:ENSP00000343535|ensembl:ENST00000381886|ensembl:ENSP00000371310|dip:DIP-29053N psi-mi:"MI:0465"(dip) crc64:E8C4A2497E44BA22 - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/05 2017/08/10 rogid:S33ZGUuOs+AAE83dREDwbnMKJws9606 rogid:V+PXXBRM2zwlGQaeFiyjaQ9yf+A9606 rigid:lVgniJqjBEU+V35tgkOsfx4Vhm0 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q96CN5 uniprotkb:Q96EK4 intact:EBI-2805176|ensembl:ENSP00000306760 intact:EBI-1790529|uniprotkb:O94795|uniprotkb:A8K002|uniprotkb:A4UCT5|ensembl:ENSP00000304689 psi-mi:lrc45_human(display_long)|uniprotkb:LRRC45(gene name)|psi-mi:LRRC45(display_short) psi-mi:tha11_human(display_long)|uniprotkb:THAP11(gene name)|psi-mi:THAP11(display_short)|uniprotkb:HRIHFB2206(orf name) psi-mi:"MI:0018"(two hybrid) DeGrado-Warren et al. (2008) pubmed:18330356|imex:IM-8752 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15690249|dip:DIP-58850E|imex:IM-8752-164 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000169683(gene)|ensembl:ENST00000306688(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR032675|refseq:NP_659436.1|dip:DIP-29482N refseq:NP_065190.2|dip:DIP-46732N|ensembl:ENSP00000304689|ensembl:ENSG00000168286(gene)|ensembl:ENST00000303596(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|interpro:IPR006612(Zinc finger, C2CH-type)|rcsb pdb:2LAU|rcsb pdb:5AJS psi-mi:"MI:0465"(dip) crc64:27F5D210721459FB crc64:25235D20CB54D8C2 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/05 2017/08/10 rogid:cuIAlpH4zLJ1La+TtOc2x4c2dMI9606 rogid:qzl6RN2xlTuDBruwyKLyDTNRCKE9606 rigid:/X5+dQ4Usq+x+r6lKd2qYytbF2g false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P02511 uniprotkb:P02511 intact:EBI-739060|uniprotkb:O43416|uniprotkb:B0YIX0|uniprotkb:Q9UC37|uniprotkb:Q9UC38|uniprotkb:Q9UC39|uniprotkb:Q9UC40|uniprotkb:Q9UC41|ensembl:ENSP00000227251|ensembl:ENSP00000433560|ensembl:ENSP00000434247|ensembl:ENSP00000435931|ensembl:ENSP00000436051|ensembl:ENSP00000436089|ensembl:ENSP00000437149|ensembl:ENSP00000483554|ensembl:ENSP00000498735|ensembl:ENSP00000499082 intact:EBI-739060|uniprotkb:O43416|uniprotkb:B0YIX0|uniprotkb:Q9UC37|uniprotkb:Q9UC38|uniprotkb:Q9UC39|uniprotkb:Q9UC40|uniprotkb:Q9UC41|ensembl:ENSP00000227251|ensembl:ENSP00000433560|ensembl:ENSP00000434247|ensembl:ENSP00000435931|ensembl:ENSP00000436051|ensembl:ENSP00000436089|ensembl:ENSP00000437149|ensembl:ENSP00000483554|ensembl:ENSP00000498735|ensembl:ENSP00000499082 psi-mi:cryab_human(display_long)|uniprotkb:CRYAB(gene name)|psi-mi:CRYAB(display_short)|uniprotkb:CRYA2(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-27(gene name synonym)|uniprotkb:"Alpha(B)-crystallin"(gene name synonym)|uniprotkb:Rosenthal fiber component(gene name synonym)|uniprotkb:Heat shock protein beta-5(gene name synonym)|uniprotkb:HSPB5(gene name synonym) psi-mi:cryab_human(display_long)|uniprotkb:CRYAB(gene name)|psi-mi:CRYAB(display_short)|uniprotkb:CRYA2(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-27(gene name synonym)|uniprotkb:"Alpha(B)-crystallin"(gene name synonym)|uniprotkb:Rosenthal fiber component(gene name synonym)|uniprotkb:Heat shock protein beta-5(gene name synonym)|uniprotkb:HSPB5(gene name synonym) psi-mi:"MI:0018"(two hybrid) DeGrado-Warren et al. (2008) pubmed:18330356|imex:IM-8752 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15690281|dip:DIP-58815E|imex:IM-8752-66 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000109846(gene)|ensembl:ENST00000227251(transcript)|ensembl:ENST00000526180(transcript)|ensembl:ENST00000527899(transcript)|ensembl:ENST00000527950(transcript)|ensembl:ENST00000531198(transcript)|ensembl:ENST00000533475(transcript)|ensembl:ENST00000533879(transcript)|ensembl:ENST00000616970(transcript)|ensembl:ENST00000650687(transcript)|ensembl:ENST00000651164(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001666"(response to hypoxia)|go:"GO:0002088"(lens development in camera-type eye)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0006936"(muscle contraction)|go:"GO:0007021"(tubulin complex assembly)|go:"GO:0007517"(muscle organ development)|go:"GO:0008017"(microtubule binding)|go:"GO:0009986"(cell surface)|go:"GO:0010259"(multicellular organism aging)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010941"(regulation of cell death)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030018"(Z disc)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030424"(axon)|go:"GO:0031109"(microtubule polymerization or depolymerization)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031430"(M band)|go:"GO:0032355"(response to estradiol)|go:"GO:0032387"(negative regulation of intracellular transport)|go:"GO:0032432"(actin filament bundle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043197"(dendritic spine)|go:"GO:0043204"(perikaryon)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051403"(stress-activated MAPK cascade)|go:"GO:0060561"(apoptotic process involved in morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0097060"(synaptic membrane)|go:"GO:0097512"(cardiac myofibril)|go:"GO:1905907"(negative regulation of amyloid fibril formation)|go:"GO:2000378"(negative regulation of reactive oxygen species metabolic process)|interpro:IPR001436(Alpha crystallin/Heat shock protein)|interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR003090(Alpha-crystallin, N-terminal)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR037882|mint:P02511|rcsb pdb:2KLR|rcsb pdb:2N0K|rcsb pdb:2WJ7|rcsb pdb:2Y1Y|rcsb pdb:2Y1Z|rcsb pdb:2YGD|rcsb pdb:3J07|rcsb pdb:2Y22|rcsb pdb:3L1G|rcsb pdb:3SGM|rcsb pdb:3SGN|rcsb pdb:3SGO|rcsb pdb:3SGP|rcsb pdb:3SGR|rcsb pdb:3SGS|rcsb pdb:4M5S|rcsb pdb:4M5T|rcsb pdb:5VVV|rcsb pdb:6BP9|reactome:R-HSA-3371571|refseq:NP_001876.1|refseq:XP_011540910.1|refseq:NP_001276736.1|refseq:NP_001276737.1|dip:DIP-35017N ensembl:ENSG00000109846(gene)|ensembl:ENST00000227251(transcript)|ensembl:ENST00000526180(transcript)|ensembl:ENST00000527899(transcript)|ensembl:ENST00000527950(transcript)|ensembl:ENST00000531198(transcript)|ensembl:ENST00000533475(transcript)|ensembl:ENST00000533879(transcript)|ensembl:ENST00000616970(transcript)|ensembl:ENST00000650687(transcript)|ensembl:ENST00000651164(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001666"(response to hypoxia)|go:"GO:0002088"(lens development in camera-type eye)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0006936"(muscle contraction)|go:"GO:0007021"(tubulin complex assembly)|go:"GO:0007517"(muscle organ development)|go:"GO:0008017"(microtubule binding)|go:"GO:0009986"(cell surface)|go:"GO:0010259"(multicellular organism aging)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010941"(regulation of cell death)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030018"(Z disc)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030424"(axon)|go:"GO:0031109"(microtubule polymerization or depolymerization)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031430"(M band)|go:"GO:0032355"(response to estradiol)|go:"GO:0032387"(negative regulation of intracellular transport)|go:"GO:0032432"(actin filament bundle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043197"(dendritic spine)|go:"GO:0043204"(perikaryon)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051403"(stress-activated MAPK cascade)|go:"GO:0060561"(apoptotic process involved in morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0097060"(synaptic membrane)|go:"GO:0097512"(cardiac myofibril)|go:"GO:1905907"(negative regulation of amyloid fibril formation)|go:"GO:2000378"(negative regulation of reactive oxygen species metabolic process)|interpro:IPR001436(Alpha crystallin/Heat shock protein)|interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR003090(Alpha-crystallin, N-terminal)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR037882|mint:P02511|rcsb pdb:2KLR|rcsb pdb:2N0K|rcsb pdb:2WJ7|rcsb pdb:2Y1Y|rcsb pdb:2Y1Z|rcsb pdb:2YGD|rcsb pdb:3J07|rcsb pdb:2Y22|rcsb pdb:3L1G|rcsb pdb:3SGM|rcsb pdb:3SGN|rcsb pdb:3SGO|rcsb pdb:3SGP|rcsb pdb:3SGR|rcsb pdb:3SGS|rcsb pdb:4M5S|rcsb pdb:4M5T|rcsb pdb:5VVV|rcsb pdb:6BP9|reactome:R-HSA-3371571|refseq:NP_001876.1|refseq:XP_011540910.1|refseq:NP_001276736.1|refseq:NP_001276737.1|dip:DIP-35017N psi-mi:"MI:0465"(dip) crc64:AE08BED46B7849CB crc64:AE08BED46B7849CB full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/05 2017/08/10 rogid:495Z42oQhkAUdADrAEOKIC5oICo9606 rogid:495Z42oQhkAUdADrAEOKIC5oICo9606 rigid:7aBGHTYzQMx7+hRsyz22EBt6WCQ false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9NVA2 uniprotkb:Q99719 intact:EBI-957999|uniprotkb:Q7L4N1|uniprotkb:Q96SP1|uniprotkb:B7Z7Z6|uniprotkb:Q4W5G1|uniprotkb:Q9UFY9|ensembl:ENSP00000264893|uniprotkb:E9KL32 intact:EBI-373345|uniprotkb:O15251|uniprotkb:Q96MY5|ensembl:ENSP00000391311 psi-mi:sep11_human(display_long)|uniprotkb:SEPTIN11(gene name)|psi-mi:SEPTIN11(display_short)|uniprotkb:SEPT11(gene name synonym) psi-mi:sept5_human(display_long)|uniprotkb:SEPTIN5(gene name)|psi-mi:SEPTIN5(display_short)|uniprotkb:Cell division control-related protein 1(gene name synonym)|uniprotkb:PNUTL1(gene name synonym)|uniprotkb:Peanut-like protein 1(gene name synonym)|uniprotkb:SEPT5(gene name synonym) psi-mi:"MI:0018"(two hybrid) DeGrado-Warren et al. (2008) pubmed:18330356|imex:IM-8752 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15690297|dip:DIP-58844E|imex:IM-8752-106 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060713.1|ensembl:ENSG00000138758(gene)|ensembl:ENST00000264893(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005940"(septin ring)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030424"(axon)|go:"GO:0031105"(septin complex)|go:"GO:0032153"(cell division site)|go:"GO:0034613"(cellular protein localization)|go:"GO:0043197"(dendritic spine)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:0099629"(postsynaptic specialization of symmetric synapse)|interpro:IPR016491(Septin)|interpro:IPR027417|interpro:IPR030379|rcsb pdb:6UPQ|refseq:NP_001293076.1|refseq:XP_016863889.1|dip:DIP-36161N refseq:NP_002679.2|refseq:NP_001009939.1|ensembl:ENSG00000184702(gene)|ensembl:ENST00000455784(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005940"(septin ring)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016080"(synaptic vesicle targeting)|go:"GO:0017157"(regulation of exocytosis)|go:"GO:0030534"(adult behavior)|go:"GO:0031105"(septin complex)|go:"GO:0032153"(cell division site)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035176"(social behavior)|go:"GO:0042802"(identical protein binding)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|interpro:IPR016491(Septin)|interpro:IPR027417|interpro:IPR030379|interpro:IPR030647|mint:Q99719|rcsb pdb:6WCU|dip:DIP-31201N psi-mi:"MI:0465"(dip) crc64:D467F1F315FFD028 crc64:47054765DEA10D33 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/05 2017/08/10 rogid:2dJm0WBfPs71hp1nBoMeGF/DR2s9606 rogid:kubhD1O+WmJeDWTlX+rcjpP9yRc9606 rigid:CSTL1d2SB9Df4vuZbOrc1Pll8OU false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P43357 uniprotkb:O00429 intact:EBI-5651459|ensembl:ENSP00000359301|ensembl:ENSP00000473093|uniprotkb:Q6FHI6 intact:EBI-724571|uniprotkb:O14541|uniprotkb:O60709|uniprotkb:Q7L6B3|uniprotkb:Q8TBT7|uniprotkb:Q9BWM1|uniprotkb:Q9Y5J2|uniprotkb:B4DSU8|uniprotkb:A8K4X9|ensembl:ENSP00000450399|uniprotkb:B4DGC9|uniprotkb:J3KPI2|uniprotkb:Q59GN9|uniprotkb:G8JLD5 psi-mi:maga3_human(display_long)|uniprotkb:MAGEA3(gene name)|psi-mi:MAGEA3(display_short)|uniprotkb:MAGE3(gene name synonym)|uniprotkb:Antigen MZ2-D(gene name synonym)|uniprotkb:Cancer/testis antigen 1.3(gene name synonym)|uniprotkb:MAGE-3 antigen(gene name synonym) psi-mi:dnm1l_human(display_long)|uniprotkb:Dynamin-like protein(gene name synonym)|uniprotkb:Dnm1p/Vps1p-like protein(gene name synonym)|uniprotkb:Dynamin family member proline-rich carboxyl-terminal domain less(gene name synonym)|uniprotkb:Dynamin-related protein 1(gene name synonym)|uniprotkb:Dynamin-like protein 4(gene name synonym)|uniprotkb:Dynamin-like protein IV(gene name synonym)|uniprotkb:DNM1L(gene name)|psi-mi:DNM1L(display_short)|uniprotkb:DLP1(gene name synonym)|uniprotkb:DRP1(gene name synonym) psi-mi:"MI:0018"(two hybrid) DeGrado-Warren et al. (2008) pubmed:18330356|imex:IM-8752 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15690313|dip:DIP-58821E|imex:IM-8752-166 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:5BRZ|ensembl:ENSG00000221867(gene)|ensembl:ENST00000370278(transcript)|ensembl:ENST00000598245(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0010955"(negative regulation of protein processing)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0089720"(caspase binding)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|interpro:IPR002190(MAGE protein)|interpro:IPR021072|interpro:IPR030097|interpro:IPR037445|interpro:IPR041898|interpro:IPR041899|rcsb pdb:1QEW|rcsb pdb:4V0P|refseq:XP_011529462.1|refseq:XP_011529463.1|refseq:NP_005353.1|dip:DIP-44886N|refseq:XP_005274733.1|refseq:XP_006724881.1 refseq:NP_005681.2|refseq:NP_036192.2|refseq:NP_036193.2|ensembl:ENSG00000087470(gene)|ensembl:ENST00000549701(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000266"(mitochondrial fission)|go:"GO:0001836"(release of cytochrome c from mitochondria)|go:"GO:0003374"(dynamin family protein polymerization involved in mitochondrial fission)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005777"(peroxisome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005903"(brush border)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0008017"(microtubule binding)|go:"GO:0008289"(lipid binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010637"(negative regulation of mitochondrial fusion)|go:"GO:0010821"(regulation of mitochondrion organization)|go:"GO:0016020"(membrane)|go:"GO:0016559"(peroxisome fission)|go:"GO:0030276"(clathrin binding)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0030742"(GTP-dependent protein binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0036466"(synaptic vesicle recycling via endosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043653"(mitochondrial fragmentation involved in apoptotic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0048312"(intracellular distribution of mitochondria)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0048511"(rhythmic process)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0051433"(BH2 domain binding)|go:"GO:0060047"(heart contraction)|go:"GO:0061003"(positive regulation of dendritic spine morphogenesis)|go:"GO:0061025"(membrane fusion)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070266"(necroptotic process)|go:"GO:0070584"(mitochondrion morphogenesis)|go:"GO:0070585"(protein localization to mitochondrion)|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:0090141"(positive regulation of mitochondrial fission)|go:"GO:0090149"(mitochondrial membrane fission)|go:"GO:0090200"(positive regulation of release of cytochrome c from mitochondria)|go:"GO:0090650"(cellular response to oxygen-glucose deprivation)|go:"GO:1900244"(positive regulation of synaptic vesicle endocytosis)|go:"GO:1903146"(regulation of autophagy of mitochondrion)|go:"GO:1903578"(regulation of ATP metabolic process)|go:"GO:1904579"(cellular response to thapsigargin)|go:"GO:1904666"(regulation of ubiquitin protein ligase activity)|go:"GO:1905395"(response to flavonoid)|go:"GO:1990910"(response to hypobaric hypoxia)|go:"GO:2000302"(positive regulation of synaptic vesicle exocytosis)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR000375(Dynamin central region)|interpro:IPR001401(Dynamin, GTPase region)|interpro:IPR003130(Dynamin GTPase effector)|interpro:IPR019762|interpro:IPR020850|interpro:IPR022812|interpro:IPR027417|interpro:IPR030381|interpro:IPR030556|mint:O00429|rcsb pdb:3W6N|rcsb pdb:3W6O|rcsb pdb:3W6P|rcsb pdb:4BEJ|rcsb pdb:4H1U|rcsb pdb:4H1V|rcsb pdb:5WP9|go:"GO:0098835"(presynaptic endocytic zone membrane)|go:"GO:1900063"(regulation of peroxisome organization)|reactome:R-HSA-75153|refseq:NP_001265392.1|refseq:NP_001265393.1|refseq:NP_001265394.1|refseq:NP_001265395.1|refseq:NP_001317309.1|dip:DIP-42704N psi-mi:"MI:0465"(dip) crc64:3F5EB13D1C9946A1 crc64:F9521A376B785B71 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/05 2017/08/10 rogid:j9zDBF6AxcqLVqpGphlXP2/AlPU9606 rogid:hmh7m80FPMdx6/3eUY6l0IK/AqY9606 rigid:ff2nKGuuAbc30HN4gQWKP9gOHOs false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q969G2 uniprotkb:O43679 intact:EBI-2865388|uniprotkb:Q8NHM1|uniprotkb:Q969W2|uniprotkb:Q8TCJ1|uniprotkb:Q8NHE0|uniprotkb:Q8WWX2|ensembl:ENSP00000263726 intact:EBI-2865580|uniprotkb:O75480|uniprotkb:O60619|ensembl:ENSP00000306772 psi-mi:lhx4_human(display_long)|uniprotkb:LHX4(gene name)|psi-mi:LHX4(display_short) psi-mi:ldb2_human(display_long)|uniprotkb:LDB2(gene name)|psi-mi:LDB2(display_short)|uniprotkb:CLIM1(gene name synonym)|uniprotkb:Carboxyl-terminal LIM domain-binding protein 1(gene name synonym)|uniprotkb:LIM domain-binding factor CLIM1(gene name synonym) psi-mi:"MI:0018"(two hybrid) DeGrado-Warren et al. (2008) pubmed:18330356|imex:IM-8752 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15690329|dip:DIP-58825E|imex:IM-8752-108 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_203129.1|dip:DIP-29454N|ensembl:ENSG00000121454(gene)|ensembl:ENST00000263726(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001890"(placenta development)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0008327"(methyl-CpG binding)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0021526"(medial motor column neuron differentiation)|go:"GO:0030182"(neuron differentiation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|mint:Q969G2|rcsb pdb:5HOD|reactome:R-HSA-9010553 refseq:NP_001124306.1|refseq:NP_001281.1|dip:DIP-24262N|dip:DIP-41215N|ensembl:ENSG00000169744(gene)|ensembl:ENST00000304523(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001942"(hair follicle development)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005886"(plasma membrane)|go:"GO:0007399"(nervous system development)|go:"GO:0010669"(epithelial structure maintenance)|go:"GO:0019899"(enzyme binding)|go:"GO:0030274"(LIM domain binding)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031252"(cell leading edge)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0043549"(regulation of kinase activity)|go:"GO:0044089"(positive regulation of cellular component biogenesis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|interpro:IPR029005|interpro:IPR030174|interpro:IPR041363 psi-mi:"MI:0465"(dip) crc64:6499F38E78B79FD1 crc64:E86387BA027F383A full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/05 2017/08/10 rogid:dCB3WgIBMdi0nNvaCFaioh+F9sw9606 rogid:3p/spcR1ariBlpLJczJxP5Mfi9w9606 rigid:Rsb3R1jHbDZkeHbr+0F9MPFjwq4 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q13137 uniprotkb:P30626 intact:EBI-739580|uniprotkb:B4DDC4|uniprotkb:E7ENK0|uniprotkb:Q53FQ5|uniprotkb:Q53HB5|uniprotkb:Q6IBN9|uniprotkb:Q9BTF7|uniprotkb:B2RBT0|ensembl:ENSP00000258947|uniprotkb:B4E0C0|uniprotkb:E7ETP5|uniprotkb:B4DDT4|uniprotkb:B4DP36|uniprotkb:E9PBE5 intact:EBI-750459|uniprotkb:D6W5Q0|intact:EBI-2623494|uniprotkb:A8MTH6|uniprotkb:B4DKK2|ensembl:ENSP00000265729 psi-mi:caco2_human(display_long)|uniprotkb:CALCOCO2(gene name)|psi-mi:CALCOCO2(display_short)|uniprotkb:NDP52(gene name synonym)|uniprotkb:Nuclear domain 10 protein NDP52(gene name synonym)|uniprotkb:Antigen nuclear dot 52 kDa protein(gene name synonym)|uniprotkb:Nuclear dot protein 52(gene name synonym) psi-mi:sorcn_human(display_long)|uniprotkb:22 kDa protein(gene name synonym)|uniprotkb:CP-22(gene name synonym)|uniprotkb:V19(gene name synonym)|uniprotkb:SRI(gene name)|psi-mi:SRI(display_short) psi-mi:"MI:0018"(two hybrid) DeGrado-Warren et al. (2008) pubmed:18330356|imex:IM-8752 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15690345|dip:DIP-58845E|imex:IM-8752-182 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001248319.1|refseq:NP_001248320.1|refseq:NP_001248322.1|refseq:NP_005822.1|ensembl:ENSG00000136436(gene)|ensembl:ENST00000258947(transcript)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016032"(viral process)|go:"GO:0016605"(PML body)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0098792"(xenophagy)|go:"GO:1901098"(positive regulation of autophagosome maturation)|interpro:IPR041611|interpro:IPR041641|mint:Q13137|rcsb pdb:2MXP|rcsb pdb:3VVV|rcsb pdb:3VVW|rcsb pdb:4GXL|rcsb pdb:4HAN|rcsb pdb:4XKL|rcsb pdb:5AAQ|rcsb pdb:5Z7A|rcsb pdb:5Z7L|refseq:NP_001248324.1|dip:DIP-57534N refseq:NP_944490.1|refseq:NP_003121.1|refseq:NP_001243820.1|refseq:NP_001243821.1|dip:DIP-40970N|ensembl:ENSG00000075142(gene)|ensembl:ENST00000265729(transcript)|go:"GO:0001508"(action potential)|go:"GO:0002020"(protease binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006880"(intracellular sequestering of iron ion)|go:"GO:0006942"(regulation of striated muscle contraction)|go:"GO:0007165"(signal transduction)|go:"GO:0007507"(heart development)|go:"GO:0007517"(muscle organ development)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0010459"(negative regulation of heart rate)|go:"GO:0030315"(T-tubule)|go:"GO:0033017"(sarcoplasmic reticulum membrane)|go:"GO:0035774"(positive regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0042802"(identical protein binding)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0043679"(axon terminus)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044326"(dendritic spine neck)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051281"(positive regulation of release of sequestered calcium ion into cytosol)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0055118"(negative regulation of cardiac muscle contraction)|go:"GO:0060315"(negative regulation of ryanodine-sensitive calcium-release channel activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0086004"(regulation of cardiac muscle cell contraction)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1901077"(regulation of relaxation of muscle)|go:"GO:1901841"(regulation of high voltage-gated calcium channel activity)|go:"GO:0010649"(regulation of cell communication by electrical coupling)|go:"GO:0010880"(regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0016020"(membrane)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0030018"(Z disc)|rcsb pdb:2JC2|rcsb pdb:4U8D|rcsb pdb:4UPG|rcsb pdb:4USL|rcsb pdb:5MRA|reactome:R-HSA-2672351|reactome:R-HSA-418359|reactome:R-HSA-425561|reactome:R-HSA-5578775|reactome:R-HSA-936837|go:"GO:1901844"(regulation of cell communication by electrical coupling involved in cardiac conduction)|go:"GO:2000678"(negative regulation of transcription regulatory region DNA binding)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|mint:P30626|rcsb pdb:1JUO psi-mi:"MI:0465"(dip) crc64:609B121DA1A9DCB8 crc64:A4829C7650A5E3FA full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/05 2017/08/10 rogid:N/GPJUGBK+Dh5Cg+csmafphuo9M9606 rogid:upE31IMimaotkgnYa7HYr7EYAxc9606 rigid:CdsceEdNYEwgLr2E6ItIKeuy0Cg false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q14141 uniprotkb:Q99719 intact:EBI-745901|uniprotkb:Q5JTK0|uniprotkb:Q969W5|uniprotkb:Q96A13|uniprotkb:Q96GR1|uniprotkb:Q96P86|uniprotkb:Q96P87|intact:EBI-1047521|ensembl:ENSP00000341524 intact:EBI-373345|uniprotkb:O15251|uniprotkb:Q96MY5|ensembl:ENSP00000391311 psi-mi:sept6_human(display_long)|uniprotkb:SEPTIN6(gene name)|psi-mi:SEPTIN6(display_short)|uniprotkb:KIAA0128(gene name synonym)|uniprotkb:SEP2(gene name synonym)|uniprotkb:SEPT6(gene name synonym) psi-mi:sept5_human(display_long)|uniprotkb:SEPTIN5(gene name)|psi-mi:SEPTIN5(display_short)|uniprotkb:Cell division control-related protein 1(gene name synonym)|uniprotkb:PNUTL1(gene name synonym)|uniprotkb:Peanut-like protein 1(gene name synonym)|uniprotkb:SEPT5(gene name synonym) psi-mi:"MI:0018"(two hybrid) DeGrado-Warren et al. (2008) pubmed:18330356|imex:IM-8752 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15690361|dip:DIP-58841E|imex:IM-8752-86 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000125354(gene)|ensembl:ENST00000343984(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0000776"(kinetochore)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005819"(spindle)|go:"GO:0005940"(septin ring)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030154"(cell differentiation)|go:"GO:0030496"(midbody)|go:"GO:0031105"(septin complex)|go:"GO:0032153"(cell division site)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032173"(septin collar)|go:"GO:0034613"(cellular protein localization)|go:"GO:0043679"(axon terminus)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis)|go:"GO:0097227"(sperm annulus)|interpro:IPR016491(Septin)|interpro:IPR027417|interpro:IPR030379|interpro:IPR030644|mint:Q14141|rcsb pdb:2QAG|rcsb pdb:6UPA|rcsb pdb:6WBP|refseq:NP_055944.2|refseq:NP_665798.1|refseq:NP_665799.1|refseq:NP_665801.1|refseq:XP_006724813.1|dip:DIP-38218N refseq:NP_002679.2|refseq:NP_001009939.1|ensembl:ENSG00000184702(gene)|ensembl:ENST00000455784(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005940"(septin ring)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016080"(synaptic vesicle targeting)|go:"GO:0017157"(regulation of exocytosis)|go:"GO:0030534"(adult behavior)|go:"GO:0031105"(septin complex)|go:"GO:0032153"(cell division site)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035176"(social behavior)|go:"GO:0042802"(identical protein binding)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|interpro:IPR016491(Septin)|interpro:IPR027417|interpro:IPR030379|interpro:IPR030647|mint:Q99719|rcsb pdb:6WCU|dip:DIP-31201N psi-mi:"MI:0465"(dip) - crc64:47054765DEA10D33 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/05 2017/08/10 rogid:gH1JHXyE/7o3I8i4ZS3bMoF7zvU9606 rogid:kubhD1O+WmJeDWTlX+rcjpP9yRc9606 rigid:onUUjwC+FyLQWnGgnvyVM+sdkJU false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q96NA2 uniprotkb:O43679 intact:EBI-2856119|uniprotkb:B2RBQ8|uniprotkb:Q9BSL3|uniprotkb:Q71RE6|uniprotkb:Q9BYS3|ensembl:ENSP00000301336|ensembl:ENSP00000481849 intact:EBI-2865580|uniprotkb:O75480|uniprotkb:O60619|ensembl:ENSP00000306772 psi-mi:rilp_human(display_long)|uniprotkb:RILP(gene name)|psi-mi:RILP(display_short)|uniprotkb:PP10141(orf name) psi-mi:ldb2_human(display_long)|uniprotkb:LDB2(gene name)|psi-mi:LDB2(display_short)|uniprotkb:CLIM1(gene name synonym)|uniprotkb:Carboxyl-terminal LIM domain-binding protein 1(gene name synonym)|uniprotkb:LIM domain-binding factor CLIM1(gene name synonym) psi-mi:"MI:0018"(two hybrid) DeGrado-Warren et al. (2008) pubmed:18330356|imex:IM-8752 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15690377|dip:DIP-58829E|imex:IM-8752-124 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_113618.2|dip:DIP-29458N|ensembl:ENSG00000167705(gene)|ensembl:ENSG00000274145(gene)|ensembl:ENST00000301336(transcript)|ensembl:ENST00000622136(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0010796"(regulation of multivesicular body size)|go:"GO:0015031"(protein transport)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032509"(endosome transport via multivesicular body sorting pathway)|go:"GO:0032991"(protein-containing complex)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0045022"(early endosome to late endosome transport)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0051959"(dynein light intermediate chain binding)|go:"GO:0060271"(cilium assembly)|go:"GO:0070676"(intralumenal vesicle formation)|interpro:IPR019143|interpro:IPR021563|interpro:IPR034743|interpro:IPR034744|rcsb pdb:1YHN|reactome:R-HSA-2132295 refseq:NP_001124306.1|refseq:NP_001281.1|dip:DIP-24262N|dip:DIP-41215N|ensembl:ENSG00000169744(gene)|ensembl:ENST00000304523(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001942"(hair follicle development)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005886"(plasma membrane)|go:"GO:0007399"(nervous system development)|go:"GO:0010669"(epithelial structure maintenance)|go:"GO:0019899"(enzyme binding)|go:"GO:0030274"(LIM domain binding)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031252"(cell leading edge)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0043549"(regulation of kinase activity)|go:"GO:0044089"(positive regulation of cellular component biogenesis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|interpro:IPR029005|interpro:IPR030174|interpro:IPR041363 psi-mi:"MI:0465"(dip) crc64:1057A1DAC2FFED94 crc64:E86387BA027F383A full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/05 2017/08/10 rogid:dBBOnpVleCSq8//uqicphTGykw09606 rogid:3p/spcR1ariBlpLJczJxP5Mfi9w9606 rigid:+L1fD1JQ+PRHk0CypdjBEpLfIdY false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P61968 uniprotkb:O43679 intact:EBI-2798728|uniprotkb:O00158|uniprotkb:O88894|uniprotkb:D3DT23|ensembl:ENSP00000359573|ensembl:ENSP00000359575 intact:EBI-2865580|uniprotkb:O75480|uniprotkb:O60619|ensembl:ENSP00000306772 psi-mi:lmo4_human(display_long)|uniprotkb:Breast tumor autoantigen(gene name synonym)|uniprotkb:LIM domain only protein 4(gene name synonym)|uniprotkb:LMO4(gene name)|psi-mi:LMO4(display_short) psi-mi:ldb2_human(display_long)|uniprotkb:LDB2(gene name)|psi-mi:LDB2(display_short)|uniprotkb:CLIM1(gene name synonym)|uniprotkb:Carboxyl-terminal LIM domain-binding protein 1(gene name synonym)|uniprotkb:LIM domain-binding factor CLIM1(gene name synonym) psi-mi:"MI:0018"(two hybrid) DeGrado-Warren et al. (2008) pubmed:18330356|imex:IM-8752 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15690393|dip:DIP-58827E|imex:IM-8752-42 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006760.1|refseq:XP_005271348.1|ensembl:ENSG00000143013(gene)|ensembl:ENST00000370542(transcript)|ensembl:ENST00000370544(transcript)|go:"GO:0001843"(neural tube closure)|go:"GO:0003281"(ventricular septum development)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0008134"(transcription factor binding)|go:"GO:0021514"(ventral spinal cord interneuron differentiation)|go:"GO:0021522"(spinal cord motor neuron differentiation)|go:"GO:0021527"(spinal cord association neuron differentiation)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031252"(cell leading edge)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0042659"(regulation of cell fate specification)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048538"(thymus development)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|interpro:IPR001781(Zinc finger, LIM-type)|mint:P61968|go:"GO:0050865"(regulation of cell activation)|rcsb pdb:2L4Z|dip:DIP-41414N refseq:NP_001124306.1|refseq:NP_001281.1|dip:DIP-24262N|dip:DIP-41215N|ensembl:ENSG00000169744(gene)|ensembl:ENST00000304523(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001942"(hair follicle development)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005886"(plasma membrane)|go:"GO:0007399"(nervous system development)|go:"GO:0010669"(epithelial structure maintenance)|go:"GO:0019899"(enzyme binding)|go:"GO:0030274"(LIM domain binding)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031252"(cell leading edge)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0043549"(regulation of kinase activity)|go:"GO:0044089"(positive regulation of cellular component biogenesis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|interpro:IPR029005|interpro:IPR030174|interpro:IPR041363 psi-mi:"MI:0465"(dip) crc64:C8AC295144AD7787 crc64:E86387BA027F383A full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/05 2017/08/10 rogid:A6F+R5tMkoNqN0nAuwTjOoVnjQE9606 rogid:3p/spcR1ariBlpLJczJxP5Mfi9w9606 rigid:pqhqoZe+3OzbDWAjQ/vzZOcb8mI false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q8WXD2 uniprotkb:O00429 intact:EBI-12162999|ensembl:ENSP00000220478|uniprotkb:A8K2B0|uniprotkb:B3KQP6|uniprotkb:B4DK99|uniprotkb:F5H3R8|uniprotkb:Q96C83|uniprotkb:Q96GE8|uniprotkb:Q9Y6G7 intact:EBI-724571|uniprotkb:O14541|uniprotkb:O60709|uniprotkb:Q7L6B3|uniprotkb:Q8TBT7|uniprotkb:Q9BWM1|uniprotkb:Q9Y5J2|uniprotkb:B4DSU8|uniprotkb:A8K4X9|ensembl:ENSP00000450399|uniprotkb:B4DGC9|uniprotkb:J3KPI2|uniprotkb:Q59GN9|uniprotkb:G8JLD5 psi-mi:scg3_human(display_long)|uniprotkb:SCG3(gene name)|psi-mi:SCG3(display_short)|uniprotkb:Secretogranin III(gene name synonym)|uniprotkb:UNQ2502/PRO5990(orf name) psi-mi:dnm1l_human(display_long)|uniprotkb:Dynamin-like protein(gene name synonym)|uniprotkb:Dnm1p/Vps1p-like protein(gene name synonym)|uniprotkb:Dynamin family member proline-rich carboxyl-terminal domain less(gene name synonym)|uniprotkb:Dynamin-related protein 1(gene name synonym)|uniprotkb:Dynamin-like protein 4(gene name synonym)|uniprotkb:Dynamin-like protein IV(gene name synonym)|uniprotkb:DNM1L(gene name)|psi-mi:DNM1L(display_short)|uniprotkb:DLP1(gene name synonym)|uniprotkb:DRP1(gene name synonym) psi-mi:"MI:0018"(two hybrid) DeGrado-Warren et al. (2008) pubmed:18330356|imex:IM-8752 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15690409|dip:DIP-58823E|imex:IM-8752-126 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000104112(gene)|ensembl:ENST00000220478(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0030658"(transport vesicle membrane)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0033366"(protein localization to secretory granule)|go:"GO:0034774"(secretory granule lumen)|interpro:IPR026197|reactome:R-HSA-114608|reactome:R-HSA-381426|reactome:R-HSA-8957275|refseq:NP_001158729.1|refseq:NP_037375.2|dip:DIP-29451N refseq:NP_005681.2|refseq:NP_036192.2|refseq:NP_036193.2|ensembl:ENSG00000087470(gene)|ensembl:ENST00000549701(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000266"(mitochondrial fission)|go:"GO:0001836"(release of cytochrome c from mitochondria)|go:"GO:0003374"(dynamin family protein polymerization involved in mitochondrial fission)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005777"(peroxisome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005903"(brush border)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0008017"(microtubule binding)|go:"GO:0008289"(lipid binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010637"(negative regulation of mitochondrial fusion)|go:"GO:0010821"(regulation of mitochondrion organization)|go:"GO:0016020"(membrane)|go:"GO:0016559"(peroxisome fission)|go:"GO:0030276"(clathrin binding)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0030742"(GTP-dependent protein binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0036466"(synaptic vesicle recycling via endosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043653"(mitochondrial fragmentation involved in apoptotic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0048312"(intracellular distribution of mitochondria)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0048511"(rhythmic process)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0051433"(BH2 domain binding)|go:"GO:0060047"(heart contraction)|go:"GO:0061003"(positive regulation of dendritic spine morphogenesis)|go:"GO:0061025"(membrane fusion)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070266"(necroptotic process)|go:"GO:0070584"(mitochondrion morphogenesis)|go:"GO:0070585"(protein localization to mitochondrion)|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:0090141"(positive regulation of mitochondrial fission)|go:"GO:0090149"(mitochondrial membrane fission)|go:"GO:0090200"(positive regulation of release of cytochrome c from mitochondria)|go:"GO:0090650"(cellular response to oxygen-glucose deprivation)|go:"GO:1900244"(positive regulation of synaptic vesicle endocytosis)|go:"GO:1903146"(regulation of autophagy of mitochondrion)|go:"GO:1903578"(regulation of ATP metabolic process)|go:"GO:1904579"(cellular response to thapsigargin)|go:"GO:1904666"(regulation of ubiquitin protein ligase activity)|go:"GO:1905395"(response to flavonoid)|go:"GO:1990910"(response to hypobaric hypoxia)|go:"GO:2000302"(positive regulation of synaptic vesicle exocytosis)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR000375(Dynamin central region)|interpro:IPR001401(Dynamin, GTPase region)|interpro:IPR003130(Dynamin GTPase effector)|interpro:IPR019762|interpro:IPR020850|interpro:IPR022812|interpro:IPR027417|interpro:IPR030381|interpro:IPR030556|mint:O00429|rcsb pdb:3W6N|rcsb pdb:3W6O|rcsb pdb:3W6P|rcsb pdb:4BEJ|rcsb pdb:4H1U|rcsb pdb:4H1V|rcsb pdb:5WP9|go:"GO:0098835"(presynaptic endocytic zone membrane)|go:"GO:1900063"(regulation of peroxisome organization)|reactome:R-HSA-75153|refseq:NP_001265392.1|refseq:NP_001265393.1|refseq:NP_001265394.1|refseq:NP_001265395.1|refseq:NP_001317309.1|dip:DIP-42704N psi-mi:"MI:0465"(dip) crc64:5E6BBDDFFF3B8D82 crc64:F9521A376B785B71 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/05 2017/08/10 rogid:4FmR4obGCv49kROnQYYVJLDoubE9606 rogid:hmh7m80FPMdx6/3eUY6l0IK/AqY9606 rigid:HJwVdUvYOyeEetU1guZqsdISrls false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q15642 uniprotkb:P42684 intact:EBI-739936|uniprotkb:O15184|uniprotkb:Q53G22|uniprotkb:Q5TZN1|uniprotkb:Q6FI24|uniprotkb:Q8NFL1|uniprotkb:Q8TCY1|uniprotkb:Q8TDX3|uniprotkb:Q96RJ1|uniprotkb:B2R8A6|uniprotkb:B7WP22|uniprotkb:D6W645|intact:EBI-28977062|ensembl:ENSP00000320117 intact:EBI-1102694|uniprotkb:Q5T0X6|uniprotkb:Q5W0C5|uniprotkb:B7UEF2|uniprotkb:B7UEF3|uniprotkb:B7UEF4|uniprotkb:B7UEF5|uniprotkb:Q6NZY6|uniprotkb:Q7Z301|ensembl:ENSP00000427562|uniprotkb:A0M8X0 psi-mi:cip4_human(display_long)|uniprotkb:TRIP10(gene name)|psi-mi:TRIP10(display_short)|uniprotkb:CIP4(gene name synonym)|uniprotkb:Thyroid receptor-interacting protein 10(gene name synonym)|uniprotkb:Protein Felic(gene name synonym)|uniprotkb:Salt tolerant protein(gene name synonym)|uniprotkb:STOT(gene name synonym)|uniprotkb:STP(gene name synonym) psi-mi:abl2_human(display_long)|uniprotkb:Abelson tyrosine-protein kinase 2(gene name synonym)|uniprotkb:ABL2(gene name)|psi-mi:ABL2(display_short)|uniprotkb:ABLL(gene name synonym)|uniprotkb:ARG(gene name synonym)|uniprotkb:Abelson murine leukemia viral oncogene homolog 2(gene name synonym)|uniprotkb:Abelson-related gene protein(gene name synonym)|uniprotkb:Tyrosine-protein kinase ARG(gene name synonym) psi-mi:"MI:0018"(two hybrid) DeGrado-Warren et al. (2008) pubmed:18330356|imex:IM-8752 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15690425|dip:DIP-58813E|imex:IM-8752-142 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSP00000320117|ensembl:ENST00000313285|ensembl:ENSP00000320493|refseq:NP_004231.1|ensembl:ENSG00000125733(gene)|ensembl:ENST00000313244(transcript)|go:"GO:0001891"(phagocytic cup)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005938"(cell cortex)|go:"GO:0006897"(endocytosis)|go:"GO:0007154"(cell communication)|go:"GO:0007165"(signal transduction)|go:"GO:0008289"(lipid binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0042802"(identical protein binding)|go:"GO:0042995"(cell projection)|interpro:IPR027267|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001060(Cdc15/Fes/CIP4)|interpro:IPR001452(Src homology-3)|interpro:IPR011072(HR1 rho-binding repeat)|interpro:IPR028498|interpro:IPR031160|interpro:IPR036028|mint:Q15642|rcsb pdb:2CT4|rcsb pdb:2EFK|rcsb pdb:2KE4|reactome:R-HSA-8856828|reactome:R-HSA-9013406|refseq:NP_001275891.1|refseq:NP_001275892.1|dip:DIP-39840N ensembl:ENSG00000143322(gene)|ensembl:ENST00000502732(transcript)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0003785"(actin monomer binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0007155"(cell adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0010863"(positive regulation of phospholipase C activity)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0018108"(peptidyl-tyrosine phosphorylation)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0030145"(manganese ion binding)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0035640"(exploration behavior)|go:"GO:0051015"(actin filament binding)|go:"GO:0051353"(positive regulation of oxidoreductase activity)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:2000145"(regulation of cell motility)|go:"GO:2000249"(regulation of actin cytoskeleton reorganization)|go:"GO:0000287"(magnesium ion binding)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR015015(F-actin binding)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR035837|interpro:IPR036028|interpro:IPR036860|mint:P42684|rcsb pdb:2ECD|rcsb pdb:2KK1|rcsb pdb:2XYN|rcsb pdb:3GVU|rcsb pdb:3HMI|rcsb pdb:3ULR|rcsb pdb:4EIH|rcsb pdb:5NP3|rcsb pdb:5NP5|reactome:R-HSA-428890|reactome:R-HSA-9013149|reactome:R-HSA-9013423|reactome:R-HSA-9706369|refseq:NP_001129472.1|refseq:NP_001129473.1|refseq:NP_001161708.1|refseq:NP_001161709.1|refseq:NP_001161710.1|refseq:NP_001161711.1|refseq:NP_005149.4|refseq:NP_009298.1|refseq:XP_005245145.1|dip:DIP-91N psi-mi:"MI:0465"(dip) crc64:A9BFE85520C7ABC5 crc64:ED93869BC2B14FAA full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/05 2017/08/10 rogid:6DvFGTlXvKhqvKlLcV1sRucCKzo9606 rogid:ct5SG4m0wewDSllBklIOi48BV7Q9606 rigid:lY0HUMM/s07XI1RAxmot7U/nMH4 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P40763 uniprotkb:P30626 intact:EBI-518675|uniprotkb:O14916|uniprotkb:Q9BW54|ensembl:ENSP00000264657|ensembl:ENSP00000467985|ensembl:ENSP00000503102|ensembl:ENSP00000503181|ensembl:ENSP00000504184|uniprotkb:A8K7B8|uniprotkb:K7ENL3 intact:EBI-750459|uniprotkb:D6W5Q0|intact:EBI-2623494|uniprotkb:A8MTH6|uniprotkb:B4DKK2|ensembl:ENSP00000265729 psi-mi:stat3_human(display_long)|uniprotkb:Acute-phase response factor(gene name synonym)|uniprotkb:STAT3(gene name)|psi-mi:STAT3(display_short)|uniprotkb:APRF(gene name synonym) psi-mi:sorcn_human(display_long)|uniprotkb:22 kDa protein(gene name synonym)|uniprotkb:CP-22(gene name synonym)|uniprotkb:V19(gene name synonym)|uniprotkb:SRI(gene name)|psi-mi:SRI(display_short) psi-mi:"MI:0018"(two hybrid) DeGrado-Warren et al. (2008) pubmed:18330356|imex:IM-8752 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15690441|dip:DIP-58848E|imex:IM-8752-144 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000168610(gene)|ensembl:ENST00000264657(transcript)|ensembl:ENST00000588969(transcript)|ensembl:ENST00000678044(transcript)|ensembl:ENST00000678906(transcript)|ensembl:ENST00000678960(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001659"(temperature homeostasis)|go:"GO:0001754"(eye photoreceptor cell differentiation)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005829"(cytosol)|go:"GO:0010730"(negative regulation of hydrogen peroxide biosynthetic process)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016310"(phosphorylation)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0019953"(sexual reproduction)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030522"(intracellular receptor signaling pathway)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031730"(CCR5 chemokine receptor binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006952"(defense response)|go:"GO:0006953"(acute-phase response)|go:"GO:0006954"(inflammatory response)|go:"GO:0007165"(signal transduction)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007259"(receptor signaling pathway via JAK-STAT)|go:"GO:0007399"(nervous system development)|go:"GO:0007568"(aging)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0032355"(response to estradiol)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032733"(positive regulation of interleukin-10 production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032870"(cellular response to hormone stimulus)|go:"GO:0033210"(leptin-mediated signaling pathway)|go:"GO:0035259"(glucocorticoid receptor binding)|go:"GO:0035591"(signaling adaptor activity)|go:"GO:0040014"(regulation of multicellular organism growth)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042493"|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042755"(eating behavior)|go:"GO:0042789"(mRNA transcription by RNA polymerase II)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0044320"(cellular response to leptin stimulus)|go:"GO:0044321"(response to leptin)|go:"GO:0045471"(response to ethanol)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0045747"(positive regulation of Notch signaling pathway)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045820"(negative regulation of glycolytic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046902"(regulation of mitochondrial membrane permeability)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048708"(astrocyte differentiation)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060019"(radial glial cell differentiation)|go:"GO:0060259"(regulation of feeding behavior)|go:"GO:0060396"(growth hormone receptor signaling pathway)|go:"GO:0060397"(growth hormone receptor signaling pathway via JAK-STAT)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070102"(interleukin-6-mediated signaling pathway)|go:"GO:0070878"(primary miRNA binding)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0072538"(T-helper 17 type immune response)|go:"GO:0072540"(T-helper 17 cell lineage commitment)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0097009"(energy homeostasis)|reactome:R-HSA-8875791|reactome:R-HSA-8983432|reactome:R-HSA-8984722|reactome:R-HSA-8985947|reactome:R-HSA-9008059|reactome:R-HSA-9020933|reactome:R-HSA-9020956|reactome:R-HSA-9020958|reactome:R-HSA-9616222|reactome:R-HSA-9670439|reactome:R-HSA-9673767|reactome:R-HSA-9673770|reactome:R-HSA-9674555|reactome:R-HSA-9705462|reactome:R-HSA-9707564|reactome:R-HSA-982772|mint:P40763|rcsb pdb:5AX3|rcsb pdb:5U5S|rcsb pdb:6NJS|rcsb pdb:6NUQ|rcsb pdb:6QHD|rcsb pdb:6TLC|reactome:R-HSA-1059683|reactome:R-HSA-111453|reactome:R-HSA-1266695|reactome:R-HSA-1433557|reactome:R-HSA-1839117|reactome:R-HSA-186763|reactome:R-HSA-198745|reactome:R-HSA-2559582|reactome:R-HSA-2586552|reactome:R-HSA-2892247|reactome:R-HSA-390471|reactome:R-HSA-452723|reactome:R-HSA-6783783|reactome:R-HSA-6785807|reactome:R-HSA-8849474|reactome:R-HSA-8854691|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099527"(postsynapse to nucleus signaling pathway)|go:"GO:1900017"(positive regulation of cytokine production involved in inflammatory response)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1902728"(positive regulation of growth factor dependent skeletal muscle satellite cell proliferation)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1904685"(positive regulation of metalloendopeptidase activity)|go:"GO:1905564"(positive regulation of vascular endothelial cell proliferation)|go:"GO:1905618"(positive regulation of miRNA-mediated gene silencing by inhibition of translation)|go:"GO:2000635"(negative regulation of primary miRNA processing)|go:"GO:2000637"(positive regulation of gene silencing by miRNA)|go:"GO:2000737"(negative regulation of stem cell differentiation)|go:"GO:2001171"(positive regulation of ATP biosynthetic process)|go:"GO:2001223"(negative regulation of neuron migration)|interpro:IPR000980(SH2 motif)|interpro:IPR001217(STAT transcription factor, core)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR012345(STAT transcription factor, DNA-binding, subdomain)|interpro:IPR013799(STAT transcription factor, protein interaction)|interpro:IPR013800(STAT transcription factor, all-alpha)|interpro:IPR013801(STAT transcription factor, DNA-binding)|interpro:IPR015988(STAT transcription factor, coiled coil)|interpro:IPR035855|interpro:IPR036535|interpro:IPR036860|refseq:NP_003141.2|refseq:NP_644805.1|refseq:NP_998827.1|refseq:XP_011523447.1|refseq:XP_011523448.1|refseq:XP_005257673.2|refseq:XP_005257674.2|refseq:XP_016880461.1|refseq:XP_016880464.1|dip:DIP-33584N refseq:NP_944490.1|refseq:NP_003121.1|refseq:NP_001243820.1|refseq:NP_001243821.1|dip:DIP-40970N|ensembl:ENSG00000075142(gene)|ensembl:ENST00000265729(transcript)|go:"GO:0001508"(action potential)|go:"GO:0002020"(protease binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006880"(intracellular sequestering of iron ion)|go:"GO:0006942"(regulation of striated muscle contraction)|go:"GO:0007165"(signal transduction)|go:"GO:0007507"(heart development)|go:"GO:0007517"(muscle organ development)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0010459"(negative regulation of heart rate)|go:"GO:0030315"(T-tubule)|go:"GO:0033017"(sarcoplasmic reticulum membrane)|go:"GO:0035774"(positive regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0042802"(identical protein binding)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0043679"(axon terminus)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044326"(dendritic spine neck)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051281"(positive regulation of release of sequestered calcium ion into cytosol)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0055118"(negative regulation of cardiac muscle contraction)|go:"GO:0060315"(negative regulation of ryanodine-sensitive calcium-release channel activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0086004"(regulation of cardiac muscle cell contraction)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1901077"(regulation of relaxation of muscle)|go:"GO:1901841"(regulation of high voltage-gated calcium channel activity)|go:"GO:0010649"(regulation of cell communication by electrical coupling)|go:"GO:0010880"(regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0016020"(membrane)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0030018"(Z disc)|rcsb pdb:2JC2|rcsb pdb:4U8D|rcsb pdb:4UPG|rcsb pdb:4USL|rcsb pdb:5MRA|reactome:R-HSA-2672351|reactome:R-HSA-418359|reactome:R-HSA-425561|reactome:R-HSA-5578775|reactome:R-HSA-936837|go:"GO:1901844"(regulation of cell communication by electrical coupling involved in cardiac conduction)|go:"GO:2000678"(negative regulation of transcription regulatory region DNA binding)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|mint:P30626|rcsb pdb:1JUO psi-mi:"MI:0465"(dip) crc64:6C00632211C8012D crc64:A4829C7650A5E3FA full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/05 2017/08/10 rogid:MEbOYO8fRKMGF0zejkJIzR6jACQ9606 rogid:upE31IMimaotkgnYa7HYr7EYAxc9606 rigid:hlKiWXHuPoWLT5V1R1EVJhapP9c false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9BWW4 uniprotkb:O43679 intact:EBI-2902395|uniprotkb:A8K0A9|uniprotkb:Q5T860|uniprotkb:Q5T861|uniprotkb:Q9BTM0|uniprotkb:Q9BWW3|ensembl:ENSP00000479674 intact:EBI-2865580|uniprotkb:O75480|uniprotkb:O60619|ensembl:ENSP00000306772 psi-mi:ssbp3_human(display_long)|uniprotkb:SSBP3(gene name)|psi-mi:SSBP3(display_short)|uniprotkb:SSDP(gene name synonym)|uniprotkb:SSDP1(gene name synonym)|uniprotkb:Sequence-specific single-stranded-DNA-binding protein(gene name synonym) psi-mi:ldb2_human(display_long)|uniprotkb:LDB2(gene name)|psi-mi:LDB2(display_short)|uniprotkb:CLIM1(gene name synonym)|uniprotkb:Carboxyl-terminal LIM domain-binding protein 1(gene name synonym)|uniprotkb:LIM domain-binding factor CLIM1(gene name synonym) psi-mi:"MI:0018"(two hybrid) DeGrado-Warren et al. (2008) pubmed:18330356|imex:IM-8752 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15690476|dip:DIP-58832E|imex:IM-8752-146 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001009955.1|refseq:NP_060540.2|refseq:NP_663768.1|dip:DIP-48897N|ensembl:ENSG00000157216(gene)|ensembl:ENST00000610401(transcript)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR006594(LisH dimerisation motif)|interpro:IPR008116(Sequence-specific single-strand DNA-binding protein)|mint:Q9BWW4 refseq:NP_001124306.1|refseq:NP_001281.1|dip:DIP-24262N|dip:DIP-41215N|ensembl:ENSG00000169744(gene)|ensembl:ENST00000304523(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001942"(hair follicle development)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005886"(plasma membrane)|go:"GO:0007399"(nervous system development)|go:"GO:0010669"(epithelial structure maintenance)|go:"GO:0019899"(enzyme binding)|go:"GO:0030274"(LIM domain binding)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031252"(cell leading edge)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0043549"(regulation of kinase activity)|go:"GO:0044089"(positive regulation of cellular component biogenesis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|interpro:IPR029005|interpro:IPR030174|interpro:IPR041363 psi-mi:"MI:0465"(dip) crc64:DBBB169D4EE10536 crc64:E86387BA027F383A full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/05 2017/08/10 rogid:GD7FO6kR/5WawTNP0MaDcmIf7f49606 rogid:3p/spcR1ariBlpLJczJxP5Mfi9w9606 rigid:L6bX54KnnkVH6crqEK3LaMbatMk false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) refseq:NP_597674 uniprotkb:P47712 intact:EBI-15690457|dip:DIP-29469N intact:EBI-1044090|uniprotkb:Q29R80|ensembl:ENSP00000356436|uniprotkb:B1AKG4 psi-mi:xage1d(display_long) psi-mi:pa24a_human(display_long)|uniprotkb:PLA2G4A(gene name)|psi-mi:PLA2G4A(display_short)|uniprotkb:CPLA2(gene name synonym)|uniprotkb:PLA2G4(gene name synonym)|uniprotkb:Phospholipase A2 group IVA(gene name synonym) psi-mi:"MI:0018"(two hybrid) DeGrado-Warren et al. (2008) pubmed:18330356|imex:IM-8752 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15690460|dip:DIP-58839E|imex:IM-8752-110 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - refseq:NP_077734.1|go:"GO:0102567"|go:"GO:0102568"|go:"GO:1902387"(ceramide 1-phosphate binding)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR002642(Lysophospholipase, catalytic region)|interpro:IPR016035(Acyl transferase/acyl hydrolase/lysophospholipase)|interpro:IPR035892|interpro:IPR041847|rcsb pdb:1BCI|rcsb pdb:1CJY|rcsb pdb:1RLW|reactome:R-HSA-111995|reactome:R-HSA-1482788|reactome:R-HSA-1482798|reactome:R-HSA-1482801|reactome:R-HSA-1482839|reactome:R-HSA-1482922|reactome:R-HSA-1482925|reactome:R-HSA-1483115|reactome:R-HSA-1483166|reactome:R-HSA-2142753|reactome:R-HSA-418592|reactome:R-HSA-432142|reactome:R-HSA-6811436|ensembl:ENSG00000116711(gene)|ensembl:ENST00000367466(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001516"(prostaglandin biosynthetic process)|go:"GO:0002827"(positive regulation of T-helper 1 type immune response)|go:"GO:0004622"(lysophospholipase activity)|go:"GO:0004623"(phospholipase A2 activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006071"(glycerol metabolic process)|go:"GO:0006640"(monoacylglycerol biosynthetic process)|go:"GO:0006663"(platelet activating factor biosynthetic process)|go:"GO:0008374"(O-acyltransferase activity)|go:"GO:0010314"(phosphatidylinositol-5-phosphate binding)|go:"GO:0010572"(positive regulation of platelet activation)|go:"GO:0019369"(arachidonic acid metabolic process)|go:"GO:0019370"(leukotriene biosynthetic process)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0032308"(positive regulation of prostaglandin secretion)|go:"GO:0034478"(phosphatidylglycerol catabolic process)|go:"GO:0034638"(phosphatidylcholine catabolic process)|go:"GO:0036151"(phosphatidylcholine acyl-chain remodeling)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043032"(positive regulation of macrophage activation)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046475"(glycerophospholipid catabolic process)|go:"GO:0047498"(calcium-dependent phospholipase A2 activity)|go:"GO:0047499"(calcium-independent phospholipase A2 activity)|go:"GO:0050482"(arachidonic acid secretion)|go:"GO:0070273"(phosphatidylinositol-4-phosphate binding)|go:"GO:0071236"(cellular response to antibiotic)|go:"GO:0102545"(phosphatidyl phospholipase B activity)|go:"GO:0006690"(icosanoid metabolic process)|refseq:NP_001298122.1|refseq:XP_011507944.1|dip:DIP-40991N psi-mi:"MI:0465"(dip) - crc64:EE71CA0EBE617856 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/05 2017/08/10 - rogid:D/yM7EFWP6xaMQ//7wutJS5D3jw9606 - false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q01518 uniprotkb:P47712 intact:EBI-2808398|ensembl:ENSP00000361878|ensembl:ENSP00000361883|ensembl:ENSP00000361891|uniprotkb:Q6I9U6|uniprotkb:Q5T0S2|uniprotkb:Q53HR7|uniprotkb:Q5T0S1 intact:EBI-1044090|uniprotkb:Q29R80|ensembl:ENSP00000356436|uniprotkb:B1AKG4 psi-mi:cap1_human(display_long)|uniprotkb:CAP1(gene name)|psi-mi:CAP1(display_short)|uniprotkb:CAP(gene name synonym) psi-mi:pa24a_human(display_long)|uniprotkb:PLA2G4A(gene name)|psi-mi:PLA2G4A(display_short)|uniprotkb:CPLA2(gene name synonym)|uniprotkb:PLA2G4(gene name synonym)|uniprotkb:Phospholipase A2 group IVA(gene name synonym) psi-mi:"MI:0018"(two hybrid) DeGrado-Warren et al. (2008) pubmed:18330356|imex:IM-8752 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15690508|dip:DIP-58836E|imex:IM-8752-112 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131236(gene)|ensembl:ENST00000372792(transcript)|ensembl:ENST00000372797(transcript)|ensembl:ENST00000372805(transcript)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0003779"(actin binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007165"(signal transduction)|go:"GO:0007190"(activation of adenylate cyclase activity)|go:"GO:0008179"(adenylate cyclase binding)|go:"GO:0019933"(cAMP-mediated signaling)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0045761"(regulation of adenylate cyclase activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001837(Adenylate cyclase-associated CAP)|interpro:IPR006599(CARP motif)|interpro:IPR013912(Adenylate cyclase-associated CAP, C-terminal)|interpro:IPR013992(Adenylate cyclase-associated CAP, N-terminal)|interpro:IPR016098(Cyclase-associated protein CAP/septum formation inhibitor MinC, C-terminal)|interpro:IPR017901|interpro:IPR018106|interpro:IPR028415|interpro:IPR028417|go:"GO:0001667"(ameboidal-type cell migration)|interpro:IPR036222|interpro:IPR036223|mint:Q01518|rcsb pdb:1K8F|reactome:R-HSA-114608|reactome:R-HSA-428890|reactome:R-HSA-6798695|refseq:XP_011538811.1|refseq:XP_011538812.1|refseq:XP_011538813.1|refseq:XP_011538814.1|refseq:XP_011538815.1|refseq:XP_011538816.1|refseq:XP_011538817.1|refseq:NP_001099000.1|refseq:NP_006358.1|refseq:XP_016855556.1|refseq:XP_016855557.1|refseq:XP_016855558.1|refseq:XP_016855559.1|refseq:XP_016855560.1|refseq:XP_016855561.1|refseq:XP_005270425.1|dip:DIP-62063N refseq:NP_077734.1|go:"GO:0102567"|go:"GO:0102568"|go:"GO:1902387"(ceramide 1-phosphate binding)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR002642(Lysophospholipase, catalytic region)|interpro:IPR016035(Acyl transferase/acyl hydrolase/lysophospholipase)|interpro:IPR035892|interpro:IPR041847|rcsb pdb:1BCI|rcsb pdb:1CJY|rcsb pdb:1RLW|reactome:R-HSA-111995|reactome:R-HSA-1482788|reactome:R-HSA-1482798|reactome:R-HSA-1482801|reactome:R-HSA-1482839|reactome:R-HSA-1482922|reactome:R-HSA-1482925|reactome:R-HSA-1483115|reactome:R-HSA-1483166|reactome:R-HSA-2142753|reactome:R-HSA-418592|reactome:R-HSA-432142|reactome:R-HSA-6811436|ensembl:ENSG00000116711(gene)|ensembl:ENST00000367466(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001516"(prostaglandin biosynthetic process)|go:"GO:0002827"(positive regulation of T-helper 1 type immune response)|go:"GO:0004622"(lysophospholipase activity)|go:"GO:0004623"(phospholipase A2 activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006071"(glycerol metabolic process)|go:"GO:0006640"(monoacylglycerol biosynthetic process)|go:"GO:0006663"(platelet activating factor biosynthetic process)|go:"GO:0008374"(O-acyltransferase activity)|go:"GO:0010314"(phosphatidylinositol-5-phosphate binding)|go:"GO:0010572"(positive regulation of platelet activation)|go:"GO:0019369"(arachidonic acid metabolic process)|go:"GO:0019370"(leukotriene biosynthetic process)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0032308"(positive regulation of prostaglandin secretion)|go:"GO:0034478"(phosphatidylglycerol catabolic process)|go:"GO:0034638"(phosphatidylcholine catabolic process)|go:"GO:0036151"(phosphatidylcholine acyl-chain remodeling)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043032"(positive regulation of macrophage activation)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046475"(glycerophospholipid catabolic process)|go:"GO:0047498"(calcium-dependent phospholipase A2 activity)|go:"GO:0047499"(calcium-independent phospholipase A2 activity)|go:"GO:0050482"(arachidonic acid secretion)|go:"GO:0070273"(phosphatidylinositol-4-phosphate binding)|go:"GO:0071236"(cellular response to antibiotic)|go:"GO:0102545"(phosphatidyl phospholipase B activity)|go:"GO:0006690"(icosanoid metabolic process)|refseq:NP_001298122.1|refseq:XP_011507944.1|dip:DIP-40991N psi-mi:"MI:0465"(dip) crc64:7789D1FAC0D1AB7B crc64:EE71CA0EBE617856 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/05 2017/08/10 rogid:BXrQm0u+e0xVOl2b+A18GrZy5Eg9606 rogid:D/yM7EFWP6xaMQ//7wutJS5D3jw9606 rigid:F6o2Q8pGycCONTOQSZJ0NRULpMs false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P18848 uniprotkb:P35638 intact:EBI-492498|uniprotkb:Q9UH31|ensembl:ENSP00000336790|ensembl:ENSP00000379912|ensembl:ENSP00000501783|ensembl:ENSP00000501863|ensembl:ENSP00000502400|ensembl:ENSP00000502610|ensembl:ENSP00000505360|ensembl:ENSP00000384587|intact:EBI-740263|uniprotkb:Q96AQ3 intact:EBI-742651|ensembl:ENSP00000340671|ensembl:ENSP00000447188|ensembl:ENSP00000494844|uniprotkb:F8VS99 psi-mi:atf4_human(display_long)|uniprotkb:Activating transcription factor 4(gene name synonym)|uniprotkb:CREB2(gene name synonym)|uniprotkb:ATF4(gene name)|psi-mi:ATF4(display_short)|uniprotkb:TXREB(gene name synonym)|uniprotkb:Cyclic AMP-responsive element-binding protein 2(gene name synonym)|uniprotkb:Tax-responsive enhancer element-binding protein 67(gene name synonym) psi-mi:ddit3_human(display_long)|uniprotkb:CHOP10(gene name synonym)|uniprotkb:C/EBP-homologous protein(gene name synonym)|uniprotkb:DDIT3(gene name)|psi-mi:DDIT3(display_short)|uniprotkb:CHOP(gene name synonym)|uniprotkb:GADD153(gene name synonym)|uniprotkb:Growth arrest and DNA damage-inducible protein GADD153(gene name synonym)|uniprotkb:C/EBP-homologous protein 10(gene name synonym)|uniprotkb:C/EBP zeta(gene name synonym)|uniprotkb:CCAAT/enhancer-binding protein homologous protein(gene name synonym) psi-mi:"MI:0018"(two hybrid) DeGrado-Warren et al. (2008) pubmed:18330356|imex:IM-8752 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15690492|dip:DIP-58816E|imex:IM-8752-88 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001666.2|refseq:NP_877962.1|ensembl:ENSG00000128272(gene)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005886"(plasma membrane)|go:"GO:0006094"(gluconeogenesis)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0008140"(cAMP response element binding protein binding)|go:"GO:0010575"(positive regulation of vascular endothelial growth factor production)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016607"(nuclear speck)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030282"(bone mineralization)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0031667"(response to nutrient levels)|go:"GO:0032057"(negative regulation of translational initiation in response to stress)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032991"(protein-containing complex)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0070309"(lens fiber cell morphogenesis)|go:"GO:0070982"(L-asparagine metabolic process)|go:"GO:0120163"(negative regulation of cold-induced thermogenesis)|go:"GO:0140467"(integrated stress response signaling)|go:"GO:0140468"(HRI-mediated signaling)|go:"GO:1903204"(negative regulation of oxidative stress-induced neuron death)|go:"GO:1903351"(cellular response to dopamine)|go:"GO:1990037"(Lewy body core)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990589"(ATF4-CREB1 transcription factor complex)|go:"GO:1990590"(ATF1-ATF4 transcription factor complex)|go:"GO:1990617"(CHOP-ATF4 complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029811|mint:P18848|rcsb pdb:1CI6|reactome:R-HSA-380994|reactome:R-HSA-381042|reactome:R-HSA-381183|reactome:R-HSA-9633012|reactome:R-HSA-9648895|go:"GO:0043005"(neuron projection)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043522"(leucine zipper domain binding)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045667"(regulation of osteoblast differentiation)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0034399"(nuclear periphery)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0034644"(cellular response to UV)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035162"(embryonic hemopoiesis)|go:"GO:0036003"(positive regulation of transcription from RNA polymerase II promoter in response to stress)|go:"GO:0036091"(positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress)|go:"GO:0036499"(PERK-mediated unfolded protein response)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042789"(mRNA transcription by RNA polymerase II)|go:"GO:0042802"(identical protein binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045943"(positive regulation of transcription by RNA polymerase I)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0061395"(positive regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|ensembl:ENST00000337304(transcript)|ensembl:ENST00000396680(transcript)|ensembl:ENST00000404241(transcript)|ensembl:ENST00000674568(transcript)|ensembl:ENST00000674835(transcript)|ensembl:ENST00000674920(transcript)|ensembl:ENST00000676346(transcript)|ensembl:ENST00000679776(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|refseq:XP_016884296.1|dip:DIP-354N refseq:NP_001181986.1|refseq:NP_004074.2|refseq:NP_001181982.1|refseq:NP_001181983.1|refseq:NP_001181984.1|ensembl:ENSG00000175197(gene)|go:"GO:0001955"(blood vessel maturation)|ensembl:ENST00000346473(transcript)|ensembl:ENST00000547303(transcript)|ensembl:ENST00000623876(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003677"(DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032792"(negative regulation of CREB transcription factor activity)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0036488"(CHOP-C/EBP complex)|go:"GO:0036499"(PERK-mediated unfolded protein response)|go:"GO:0036500"(ATF6-mediated unfolded protein response)|go:"GO:0042594"(response to starvation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043522"(leucine zipper domain binding)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0032713"(negative regulation of interleukin-4 production)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0006983"(ER overload response)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0007049"(cell cycle)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008140"(cAMP response element binding protein binding)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0005737"(cytoplasm)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0005770"(late endosome)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032689"(negative regulation of interferon-gamma production)|go:"GO:0032700"(negative regulation of interleukin-17 production)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0051209"(release of sequestered calcium ion into cytosol)|go:"GO:0051898"(negative regulation of protein kinase B signaling)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0072655"(establishment of protein localization to mitochondrion)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0120163"(negative regulation of cold-induced thermogenesis)|go:"GO:0140416"(transcription regulator inhibitor activity)|go:"GO:1902237"(positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903026"(negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990442"(intrinsic apoptotic signaling pathway in response to nitrosative stress)|go:"GO:1990617"(CHOP-ATF4 complex)|go:"GO:1990622"(CHOP-ATF3 complex)|go:"GO:2000016"(negative regulation of determination of dorsal identity)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR016670(DNA damage-inducible transcript 3)|mint:P35638|reactome:R-HSA-380994|reactome:R-HSA-381183|reactome:R-HSA-9614657|reactome:R-HSA-9633012|reactome:R-HSA-9648895|go:"GO:0043618"(regulation of transcription from RNA polymerase II promoter in response to stress)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045662"(negative regulation of myoblast differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|dip:DIP-41589N psi-mi:"MI:0465"(dip) crc64:3BBB7379DC3B0D07|comment:"No Uniprot Update and Caution removed \" The protein could not be merged with EBI-12907955 because of some conflicts with the protein sequence (features which cannot be shifted).\" -EBI-12907955 no longer exists." crc64:31905293FB1FBBE2 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/05 2017/08/10 rogid:2UolKWXxKFddysaOo70/U/1pI5k9606 rogid:xyMsMwPwid+S2IYb3H0K0pnUc309606 rigid:KwPeFIhAna0H050uZOZfO96jD/o false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P31350 uniprotkb:O00429 intact:EBI-2339245|uniprotkb:B2R9B5|uniprotkb:Q5WRU7|uniprotkb:J3KP43|intact:EBI-10973436|ensembl:ENSP00000302955|ensembl:ENSP00000493399 intact:EBI-724571|uniprotkb:O14541|uniprotkb:O60709|uniprotkb:Q7L6B3|uniprotkb:Q8TBT7|uniprotkb:Q9BWM1|uniprotkb:Q9Y5J2|uniprotkb:B4DSU8|uniprotkb:A8K4X9|ensembl:ENSP00000450399|uniprotkb:B4DGC9|uniprotkb:J3KPI2|uniprotkb:Q59GN9|uniprotkb:G8JLD5 psi-mi:rir2_human(display_long)|uniprotkb:RRM2(gene name)|psi-mi:RRM2(display_short)|uniprotkb:RR2(gene name synonym)|uniprotkb:Ribonucleotide reductase small subunit(gene name synonym)|uniprotkb:Ribonucleotide reductase small chain(gene name synonym) psi-mi:dnm1l_human(display_long)|uniprotkb:Dynamin-like protein(gene name synonym)|uniprotkb:Dnm1p/Vps1p-like protein(gene name synonym)|uniprotkb:Dynamin family member proline-rich carboxyl-terminal domain less(gene name synonym)|uniprotkb:Dynamin-related protein 1(gene name synonym)|uniprotkb:Dynamin-like protein 4(gene name synonym)|uniprotkb:Dynamin-like protein IV(gene name synonym)|uniprotkb:DNM1L(gene name)|psi-mi:DNM1L(display_short)|uniprotkb:DLP1(gene name synonym)|uniprotkb:DRP1(gene name synonym) psi-mi:"MI:0018"(two hybrid) DeGrado-Warren et al. (2008) pubmed:18330356|imex:IM-8752 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15690524|dip:DIP-58822E|imex:IM-8752-68 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001025.1|refseq:NP_001159403.1|dip:DIP-24232N|ensembl:ENSG00000171848(gene)|ensembl:ENST00000304567(transcript)|ensembl:ENST00000641198(transcript)|go:"GO:0001824"(blastocyst development)|go:"GO:0004748"(ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor)|go:"GO:0005829"(cytosol)|go:"GO:0005971"(ribonucleoside-diphosphate reductase complex)|go:"GO:0006260"(DNA replication)|go:"GO:0008199"(ferric iron binding)|go:"GO:0009263"(deoxyribonucleotide biosynthetic process)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0051290"(protein heterotetramerization)|interpro:IPR000358(Ribonucleotide reductase)|interpro:IPR009078(Ferritin/ribonucleotide reductase-like)|interpro:IPR012348(Ribonucleotide reductase-related)|interpro:IPR030475|interpro:IPR033909|rcsb pdb:2UW2|rcsb pdb:3OLJ|rcsb pdb:3VPM|rcsb pdb:3VPN|rcsb pdb:3VPO|reactome:R-HSA-499943|reactome:R-HSA-69205|reactome:R-HSA-8953750 refseq:NP_005681.2|refseq:NP_036192.2|refseq:NP_036193.2|ensembl:ENSG00000087470(gene)|ensembl:ENST00000549701(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000266"(mitochondrial fission)|go:"GO:0001836"(release of cytochrome c from mitochondria)|go:"GO:0003374"(dynamin family protein polymerization involved in mitochondrial fission)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005777"(peroxisome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005903"(brush border)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0008017"(microtubule binding)|go:"GO:0008289"(lipid binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010637"(negative regulation of mitochondrial fusion)|go:"GO:0010821"(regulation of mitochondrion organization)|go:"GO:0016020"(membrane)|go:"GO:0016559"(peroxisome fission)|go:"GO:0030276"(clathrin binding)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0030742"(GTP-dependent protein binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0036466"(synaptic vesicle recycling via endosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043653"(mitochondrial fragmentation involved in apoptotic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0048312"(intracellular distribution of mitochondria)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0048511"(rhythmic process)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0051433"(BH2 domain binding)|go:"GO:0060047"(heart contraction)|go:"GO:0061003"(positive regulation of dendritic spine morphogenesis)|go:"GO:0061025"(membrane fusion)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070266"(necroptotic process)|go:"GO:0070584"(mitochondrion morphogenesis)|go:"GO:0070585"(protein localization to mitochondrion)|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:0090141"(positive regulation of mitochondrial fission)|go:"GO:0090149"(mitochondrial membrane fission)|go:"GO:0090200"(positive regulation of release of cytochrome c from mitochondria)|go:"GO:0090650"(cellular response to oxygen-glucose deprivation)|go:"GO:1900244"(positive regulation of synaptic vesicle endocytosis)|go:"GO:1903146"(regulation of autophagy of mitochondrion)|go:"GO:1903578"(regulation of ATP metabolic process)|go:"GO:1904579"(cellular response to thapsigargin)|go:"GO:1904666"(regulation of ubiquitin protein ligase activity)|go:"GO:1905395"(response to flavonoid)|go:"GO:1990910"(response to hypobaric hypoxia)|go:"GO:2000302"(positive regulation of synaptic vesicle exocytosis)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR000375(Dynamin central region)|interpro:IPR001401(Dynamin, GTPase region)|interpro:IPR003130(Dynamin GTPase effector)|interpro:IPR019762|interpro:IPR020850|interpro:IPR022812|interpro:IPR027417|interpro:IPR030381|interpro:IPR030556|mint:O00429|rcsb pdb:3W6N|rcsb pdb:3W6O|rcsb pdb:3W6P|rcsb pdb:4BEJ|rcsb pdb:4H1U|rcsb pdb:4H1V|rcsb pdb:5WP9|go:"GO:0098835"(presynaptic endocytic zone membrane)|go:"GO:1900063"(regulation of peroxisome organization)|reactome:R-HSA-75153|refseq:NP_001265392.1|refseq:NP_001265393.1|refseq:NP_001265394.1|refseq:NP_001265395.1|refseq:NP_001317309.1|dip:DIP-42704N psi-mi:"MI:0465"(dip) - crc64:F9521A376B785B71 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/05 2017/08/10 rogid:vkkD9wGSPnsXX89dIQ53fhLD7uI9606 rogid:hmh7m80FPMdx6/3eUY6l0IK/AqY9606 rigid:IH87jmmC35trALvjkQVc45YiUys false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q14141 uniprotkb:Q99719 intact:EBI-745901|uniprotkb:Q5JTK0|uniprotkb:Q969W5|uniprotkb:Q96A13|uniprotkb:Q96GR1|uniprotkb:Q96P86|uniprotkb:Q96P87|intact:EBI-1047521|ensembl:ENSP00000341524 intact:EBI-373345|uniprotkb:O15251|uniprotkb:Q96MY5|ensembl:ENSP00000391311 psi-mi:sept6_human(display_long)|uniprotkb:SEPTIN6(gene name)|psi-mi:SEPTIN6(display_short)|uniprotkb:KIAA0128(gene name synonym)|uniprotkb:SEP2(gene name synonym)|uniprotkb:SEPT6(gene name synonym) psi-mi:sept5_human(display_long)|uniprotkb:SEPTIN5(gene name)|psi-mi:SEPTIN5(display_short)|uniprotkb:Cell division control-related protein 1(gene name synonym)|uniprotkb:PNUTL1(gene name synonym)|uniprotkb:Peanut-like protein 1(gene name synonym)|uniprotkb:SEPT5(gene name synonym) psi-mi:"MI:0018"(two hybrid) DeGrado-Warren et al. (2008) pubmed:18330356|imex:IM-8752 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15690540|dip:DIP-58842E|imex:IM-8752-148 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000125354(gene)|ensembl:ENST00000343984(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0000776"(kinetochore)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005819"(spindle)|go:"GO:0005940"(septin ring)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030154"(cell differentiation)|go:"GO:0030496"(midbody)|go:"GO:0031105"(septin complex)|go:"GO:0032153"(cell division site)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032173"(septin collar)|go:"GO:0034613"(cellular protein localization)|go:"GO:0043679"(axon terminus)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis)|go:"GO:0097227"(sperm annulus)|interpro:IPR016491(Septin)|interpro:IPR027417|interpro:IPR030379|interpro:IPR030644|mint:Q14141|rcsb pdb:2QAG|rcsb pdb:6UPA|rcsb pdb:6WBP|refseq:NP_055944.2|refseq:NP_665798.1|refseq:NP_665799.1|refseq:NP_665801.1|refseq:XP_006724813.1|dip:DIP-38218N refseq:NP_002679.2|refseq:NP_001009939.1|ensembl:ENSG00000184702(gene)|ensembl:ENST00000455784(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005940"(septin ring)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016080"(synaptic vesicle targeting)|go:"GO:0017157"(regulation of exocytosis)|go:"GO:0030534"(adult behavior)|go:"GO:0031105"(septin complex)|go:"GO:0032153"(cell division site)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035176"(social behavior)|go:"GO:0042802"(identical protein binding)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|interpro:IPR016491(Septin)|interpro:IPR027417|interpro:IPR030379|interpro:IPR030647|mint:Q99719|rcsb pdb:6WCU|dip:DIP-31201N psi-mi:"MI:0465"(dip) - crc64:47054765DEA10D33 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/05 2017/08/10 rogid:gH1JHXyE/7o3I8i4ZS3bMoF7zvU9606 rogid:kubhD1O+WmJeDWTlX+rcjpP9yRc9606 rigid:onUUjwC+FyLQWnGgnvyVM+sdkJU false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q99961 uniprotkb:O00429 intact:EBI-697911|uniprotkb:Q99668|uniprotkb:B4DRA1|uniprotkb:E7EVZ4|uniprotkb:M0QZV5|ensembl:ENSP00000269886 intact:EBI-724571|uniprotkb:O14541|uniprotkb:O60709|uniprotkb:Q7L6B3|uniprotkb:Q8TBT7|uniprotkb:Q9BWM1|uniprotkb:Q9Y5J2|uniprotkb:B4DSU8|uniprotkb:A8K4X9|ensembl:ENSP00000450399|uniprotkb:B4DGC9|uniprotkb:J3KPI2|uniprotkb:Q59GN9|uniprotkb:G8JLD5 psi-mi:sh3g1_human(display_long)|uniprotkb:Endophilin-2(gene name synonym)|uniprotkb:SH3 domain-containing GRB2-like protein 1(gene name synonym)|uniprotkb:SH3 domain protein 2B(gene name synonym)|uniprotkb:Extra eleven-nineteen leukemia fusion gene protein(gene name synonym)|uniprotkb:EEN fusion partner of MLL(gene name synonym)|uniprotkb:SH3GL1(gene name)|psi-mi:SH3GL1(display_short)|uniprotkb:CNSA1(gene name synonym)|uniprotkb:SH3D2B(gene name synonym) psi-mi:dnm1l_human(display_long)|uniprotkb:Dynamin-like protein(gene name synonym)|uniprotkb:Dnm1p/Vps1p-like protein(gene name synonym)|uniprotkb:Dynamin family member proline-rich carboxyl-terminal domain less(gene name synonym)|uniprotkb:Dynamin-related protein 1(gene name synonym)|uniprotkb:Dynamin-like protein 4(gene name synonym)|uniprotkb:Dynamin-like protein IV(gene name synonym)|uniprotkb:DNM1L(gene name)|psi-mi:DNM1L(display_short)|uniprotkb:DLP1(gene name synonym)|uniprotkb:DRP1(gene name synonym) psi-mi:"MI:0018"(two hybrid) DeGrado-Warren et al. (2008) pubmed:18330356|imex:IM-8752 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15690556|dip:DIP-58824E|imex:IM-8752-44 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001186872.1|refseq:NP_003016.1|refseq:NP_001186873.1|dip:DIP-29452N|ensembl:ENSG00000141985(gene)|ensembl:ENST00000269886(transcript)|go:"GO:0002102"(podosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007165"(signal transduction)|go:"GO:0007417"(central nervous system development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008289"(lipid binding)|go:"GO:0016191"(synaptic vesicle uncoating)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019902"(phosphatase binding)|go:"GO:0031697"(beta-1 adrenergic receptor binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042995"(cell projection)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0051020"(GTPase binding)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098793"(presynapse)|go:"GO:0098815"(modulation of excitatory postsynaptic potential)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:1900244"(positive regulation of synaptic vesicle endocytosis)|interpro:IPR001452(Src homology-3)|interpro:IPR004148(BAR)|interpro:IPR027267|interpro:IPR028501|interpro:IPR035824|interpro:IPR036028|mint:Q99961|reactome:R-HSA-182971|reactome:R-HSA-6807004|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8875360 refseq:NP_005681.2|refseq:NP_036192.2|refseq:NP_036193.2|ensembl:ENSG00000087470(gene)|ensembl:ENST00000549701(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000266"(mitochondrial fission)|go:"GO:0001836"(release of cytochrome c from mitochondria)|go:"GO:0003374"(dynamin family protein polymerization involved in mitochondrial fission)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005777"(peroxisome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005903"(brush border)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0008017"(microtubule binding)|go:"GO:0008289"(lipid binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010637"(negative regulation of mitochondrial fusion)|go:"GO:0010821"(regulation of mitochondrion organization)|go:"GO:0016020"(membrane)|go:"GO:0016559"(peroxisome fission)|go:"GO:0030276"(clathrin binding)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0030742"(GTP-dependent protein binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0036466"(synaptic vesicle recycling via endosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043653"(mitochondrial fragmentation involved in apoptotic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0048312"(intracellular distribution of mitochondria)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0048511"(rhythmic process)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0051433"(BH2 domain binding)|go:"GO:0060047"(heart contraction)|go:"GO:0061003"(positive regulation of dendritic spine morphogenesis)|go:"GO:0061025"(membrane fusion)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070266"(necroptotic process)|go:"GO:0070584"(mitochondrion morphogenesis)|go:"GO:0070585"(protein localization to mitochondrion)|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:0090141"(positive regulation of mitochondrial fission)|go:"GO:0090149"(mitochondrial membrane fission)|go:"GO:0090200"(positive regulation of release of cytochrome c from mitochondria)|go:"GO:0090650"(cellular response to oxygen-glucose deprivation)|go:"GO:1900244"(positive regulation of synaptic vesicle endocytosis)|go:"GO:1903146"(regulation of autophagy of mitochondrion)|go:"GO:1903578"(regulation of ATP metabolic process)|go:"GO:1904579"(cellular response to thapsigargin)|go:"GO:1904666"(regulation of ubiquitin protein ligase activity)|go:"GO:1905395"(response to flavonoid)|go:"GO:1990910"(response to hypobaric hypoxia)|go:"GO:2000302"(positive regulation of synaptic vesicle exocytosis)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR000375(Dynamin central region)|interpro:IPR001401(Dynamin, GTPase region)|interpro:IPR003130(Dynamin GTPase effector)|interpro:IPR019762|interpro:IPR020850|interpro:IPR022812|interpro:IPR027417|interpro:IPR030381|interpro:IPR030556|mint:O00429|rcsb pdb:3W6N|rcsb pdb:3W6O|rcsb pdb:3W6P|rcsb pdb:4BEJ|rcsb pdb:4H1U|rcsb pdb:4H1V|rcsb pdb:5WP9|go:"GO:0098835"(presynaptic endocytic zone membrane)|go:"GO:1900063"(regulation of peroxisome organization)|reactome:R-HSA-75153|refseq:NP_001265392.1|refseq:NP_001265393.1|refseq:NP_001265394.1|refseq:NP_001265395.1|refseq:NP_001317309.1|dip:DIP-42704N psi-mi:"MI:0465"(dip) crc64:6E5BE978BC955077 crc64:F9521A376B785B71 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/05 2017/08/10 rogid:Qzz+R0MGXEpZ6G0xoPglUBKBIfk9606 rogid:hmh7m80FPMdx6/3eUY6l0IK/AqY9606 rigid:ecvPL0lSeWdxlhnnZ/pJ/uxgSn4 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q99598 uniprotkb:O43679 intact:EBI-742638|intact:EBI-1050136|uniprotkb:B1APC6|refseq:NP_005990|dip:DIP-29463N intact:EBI-2865580|uniprotkb:O75480|uniprotkb:O60619|ensembl:ENSP00000306772 psi-mi:tsnax_human(display_long)|uniprotkb:Translin-associated factor X(gene name synonym)|uniprotkb:TSNAX(gene name)|psi-mi:TSNAX(display_short)|uniprotkb:TRAX(gene name synonym) psi-mi:ldb2_human(display_long)|uniprotkb:LDB2(gene name)|psi-mi:LDB2(display_short)|uniprotkb:CLIM1(gene name synonym)|uniprotkb:Carboxyl-terminal LIM domain-binding protein 1(gene name synonym)|uniprotkb:LIM domain-binding factor CLIM1(gene name synonym) psi-mi:"MI:0018"(two hybrid) DeGrado-Warren et al. (2008) pubmed:18330356|imex:IM-8752 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15690572|dip:DIP-58834E|imex:IM-8752-70 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005634"(nucleus)|go:"GO:0008565"(obsolete protein transporter activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0007275"(multicellular organism development)|go:"GO:0007283"(spermatogenesis)|refseq:NP_005990.1|interpro:IPR002848(Translin)|interpro:IPR016068(Translin, N-terminal)|rcsb pdb:3PJA|rcsb pdb:3QB5|ensembl:ENST00000366639|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0031047"(gene silencing by RNA)|reactome:R-HSA-426486|go:"GO:0030422"(production of siRNA involved in RNA interference)|interpro:IPR036081|go:"GO:0003677"(DNA binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0046872"(metal ion binding)|go:"GO:0005829"(cytosol)|ensembl:ENSG00000116918|ensembl:ENSP00000355599|go:"GO:0005654"(nucleoplasm)|go:"GO:0003723"(RNA binding)|dip:DIP-29463N|mint:MINT-1347706|go:"GO:0044822"|interpro:IPR016069(Translin, C-terminal)|go:"GO:0031687"(A2A adenosine receptor binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0004521"(endoribonuclease activity)|go:"GO:0003697"(single-stranded DNA binding) refseq:NP_001124306.1|refseq:NP_001281.1|dip:DIP-24262N|dip:DIP-41215N|ensembl:ENSG00000169744(gene)|ensembl:ENST00000304523(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001942"(hair follicle development)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005886"(plasma membrane)|go:"GO:0007399"(nervous system development)|go:"GO:0010669"(epithelial structure maintenance)|go:"GO:0019899"(enzyme binding)|go:"GO:0030274"(LIM domain binding)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031252"(cell leading edge)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0043549"(regulation of kinase activity)|go:"GO:0044089"(positive regulation of cellular component biogenesis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|interpro:IPR029005|interpro:IPR030174|interpro:IPR041363 psi-mi:"MI:0465"(dip) crc64:D38B0DD96B50C0B9|no-uniprot-update:|caution:"The protein could not be merged with EBI-12908040 because of some conflicts with the protein sequence (features which cannot be shifted)." crc64:E86387BA027F383A full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/05 2017/08/10 rogid:TaNIxjLHGusdq32WbdJ21DG9yBQ9606 rogid:3p/spcR1ariBlpLJczJxP5Mfi9w9606 rigid:ePz0nXyMGmGd/XPJs5yTmkAcjvA false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q5U651 uniprotkb:O43679 intact:EBI-2797123|uniprotkb:Q6U676|ensembl:ENSP00000222145 intact:EBI-2865580|uniprotkb:O75480|uniprotkb:O60619|ensembl:ENSP00000306772 psi-mi:rain_human(display_long)|uniprotkb:RASIP1(gene name)|psi-mi:RASIP1(display_short) psi-mi:ldb2_human(display_long)|uniprotkb:LDB2(gene name)|psi-mi:LDB2(display_short)|uniprotkb:CLIM1(gene name synonym)|uniprotkb:Carboxyl-terminal LIM domain-binding protein 1(gene name synonym)|uniprotkb:LIM domain-binding factor CLIM1(gene name synonym) psi-mi:"MI:0018"(two hybrid) DeGrado-Warren et al. (2008) pubmed:18330356|imex:IM-8752 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15690604|dip:DIP-58828E|imex:IM-8752-90 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) dip:DIP-29457N|refseq:NP_060275.2|ensembl:ENSG00000105538(gene)|ensembl:ENST00000222145(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001570"(vasculogenesis)|go:"GO:0005795"(Golgi stack)|go:"GO:0005911"(cell-cell junction)|go:"GO:0007165"(signal transduction)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033625"(positive regulation of integrin activation)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0051020"(GTPase binding)|go:"GO:1905709"(negative regulation of membrane permeability)|go:"GO:2000299"(negative regulation of Rho-dependent protein serine/threonine kinase activity)|interpro:IPR002710(Dilute)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR029071|interpro:IPR037983|rcsb pdb:5KHO|rcsb pdb:5KHQ|interpro:IPR000159(Ras-association) refseq:NP_001124306.1|refseq:NP_001281.1|dip:DIP-24262N|dip:DIP-41215N|ensembl:ENSG00000169744(gene)|ensembl:ENST00000304523(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001942"(hair follicle development)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005886"(plasma membrane)|go:"GO:0007399"(nervous system development)|go:"GO:0010669"(epithelial structure maintenance)|go:"GO:0019899"(enzyme binding)|go:"GO:0030274"(LIM domain binding)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031252"(cell leading edge)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0043549"(regulation of kinase activity)|go:"GO:0044089"(positive regulation of cellular component biogenesis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|interpro:IPR029005|interpro:IPR030174|interpro:IPR041363 psi-mi:"MI:0465"(dip) crc64:470021F91B59EC52 crc64:E86387BA027F383A full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/05 2017/08/10 rogid:L0Vu21+1Ec4kZs0C89QTTABdvnA9606 rogid:3p/spcR1ariBlpLJczJxP5Mfi9w9606 rigid:U164Ce4FCAmEoasGE0REQ6KAx+0 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q04323 uniprotkb:P47712 intact:EBI-1058647|ensembl:ENSP00000303991|uniprotkb:Q9BV93|uniprotkb:Q9BVV5|intact:EBI-1993649 intact:EBI-1044090|uniprotkb:Q29R80|ensembl:ENSP00000356436|uniprotkb:B1AKG4 psi-mi:ubxn1_human(display_long)|uniprotkb:UBXN1(gene name)|psi-mi:UBXN1(display_short)|uniprotkb:SAKS1(gene name synonym)|uniprotkb:SAPK substrate protein 1(gene name synonym)|uniprotkb:UBA/UBX 33.3 kDa protein(gene name synonym) psi-mi:pa24a_human(display_long)|uniprotkb:PLA2G4A(gene name)|psi-mi:PLA2G4A(display_short)|uniprotkb:CPLA2(gene name synonym)|uniprotkb:PLA2G4(gene name synonym)|uniprotkb:Phospholipase A2 group IVA(gene name synonym) psi-mi:"MI:0018"(two hybrid) DeGrado-Warren et al. (2008) pubmed:18330356|imex:IM-8752 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15690588|dip:DIP-58837E|imex:IM-8752-150 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000162191(gene)|ensembl:ENST00000301935(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0030425"(dendrite)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0034098"(VCP-NPL4-UFD1 AAA ATPase complex)|go:"GO:0036435"(K48-linked polyubiquitin modification-dependent protein binding)|refseq:NP_001273006.1|refseq:NP_001273007.1|refseq:NP_056937.2|go:"GO:0043025"(neuronal cell body)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0051117"(ATPase binding)|go:"GO:0071796"(K6-linked polyubiquitin modification-dependent protein binding)|go:"GO:1903094"(negative regulation of protein K48-linked deubiquitination)|go:"GO:1904293"(negative regulation of ERAD pathway)|go:"GO:1904855"(proteasome regulatory particle binding)|go:"GO:2000157"(negative regulation of ubiquitin-specific protease activity)|interpro:IPR001012(UBX)|interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR029071|interpro:IPR041923|reactome:R-HSA-532668|reactome:R-HSA-5693565|go:"GO:0043130"(ubiquitin binding)|refseq:XP_005274090.1|refseq:XP_016873363.1|dip:DIP-29467N refseq:NP_077734.1|go:"GO:0102567"|go:"GO:0102568"|go:"GO:1902387"(ceramide 1-phosphate binding)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR002642(Lysophospholipase, catalytic region)|interpro:IPR016035(Acyl transferase/acyl hydrolase/lysophospholipase)|interpro:IPR035892|interpro:IPR041847|rcsb pdb:1BCI|rcsb pdb:1CJY|rcsb pdb:1RLW|reactome:R-HSA-111995|reactome:R-HSA-1482788|reactome:R-HSA-1482798|reactome:R-HSA-1482801|reactome:R-HSA-1482839|reactome:R-HSA-1482922|reactome:R-HSA-1482925|reactome:R-HSA-1483115|reactome:R-HSA-1483166|reactome:R-HSA-2142753|reactome:R-HSA-418592|reactome:R-HSA-432142|reactome:R-HSA-6811436|ensembl:ENSG00000116711(gene)|ensembl:ENST00000367466(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001516"(prostaglandin biosynthetic process)|go:"GO:0002827"(positive regulation of T-helper 1 type immune response)|go:"GO:0004622"(lysophospholipase activity)|go:"GO:0004623"(phospholipase A2 activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006071"(glycerol metabolic process)|go:"GO:0006640"(monoacylglycerol biosynthetic process)|go:"GO:0006663"(platelet activating factor biosynthetic process)|go:"GO:0008374"(O-acyltransferase activity)|go:"GO:0010314"(phosphatidylinositol-5-phosphate binding)|go:"GO:0010572"(positive regulation of platelet activation)|go:"GO:0019369"(arachidonic acid metabolic process)|go:"GO:0019370"(leukotriene biosynthetic process)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0032308"(positive regulation of prostaglandin secretion)|go:"GO:0034478"(phosphatidylglycerol catabolic process)|go:"GO:0034638"(phosphatidylcholine catabolic process)|go:"GO:0036151"(phosphatidylcholine acyl-chain remodeling)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043032"(positive regulation of macrophage activation)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046475"(glycerophospholipid catabolic process)|go:"GO:0047498"(calcium-dependent phospholipase A2 activity)|go:"GO:0047499"(calcium-independent phospholipase A2 activity)|go:"GO:0050482"(arachidonic acid secretion)|go:"GO:0070273"(phosphatidylinositol-4-phosphate binding)|go:"GO:0071236"(cellular response to antibiotic)|go:"GO:0102545"(phosphatidyl phospholipase B activity)|go:"GO:0006690"(icosanoid metabolic process)|refseq:NP_001298122.1|refseq:XP_011507944.1|dip:DIP-40991N psi-mi:"MI:0465"(dip) crc64:E4E0C8BBAC93F2BB crc64:EE71CA0EBE617856 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/05 2017/08/10 rogid:KdHMRM9FSd6VT6MvJTxzdjARlRw9606 rogid:D/yM7EFWP6xaMQ//7wutJS5D3jw9606 rigid:r7cFf7DeMD6BPWwTz+ZgiSaG3FY false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P81877 uniprotkb:O43679 intact:EBI-748077|uniprotkb:Q8N2Q2|uniprotkb:Q9BWW6|uniprotkb:Q9Y4T7|uniprotkb:B7Z2L9|uniprotkb:E9PDA8|uniprotkb:B2R5W1|uniprotkb:B7Z1J2|uniprotkb:B7Z665|uniprotkb:D6RH18|uniprotkb:E9PB74|intact:EBI-28967061|ensembl:ENSP00000322977 intact:EBI-2865580|uniprotkb:O75480|uniprotkb:O60619|ensembl:ENSP00000306772 psi-mi:ssbp2_human(display_long)|uniprotkb:Sequence-specific single-stranded-DNA-binding protein 2(gene name synonym)|uniprotkb:SSBP2(gene name)|psi-mi:SSBP2(display_short)|uniprotkb:SSDP2(gene name synonym) psi-mi:ldb2_human(display_long)|uniprotkb:LDB2(gene name)|psi-mi:LDB2(display_short)|uniprotkb:CLIM1(gene name synonym)|uniprotkb:Carboxyl-terminal LIM domain-binding protein 1(gene name synonym)|uniprotkb:LIM domain-binding factor CLIM1(gene name synonym) psi-mi:"MI:0018"(two hybrid) DeGrado-Warren et al. (2008) pubmed:18330356|imex:IM-8752 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15690620|dip:DIP-58830E|imex:IM-8752-184 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSP00000322977|ensembl:ENST00000505980|ensembl:ENSP00000423969|ensembl:ENST00000509053|ensembl:ENSP00000422961|ensembl:ENST00000514493|ensembl:ENSP00000426183|ensembl:ENST00000515395|ensembl:ENSP00000424657|refseq:NP_001243661.1|refseq:NP_036578.2|refseq:NP_001243665.1|refseq:NP_001243663.1|refseq:NP_001243664.1|refseq:NP_001243662.1|ensembl:ENSG00000145687(gene)|ensembl:ENST00000320672(transcript)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR006594(LisH dimerisation motif)|interpro:IPR008116(Sequence-specific single-strand DNA-binding protein)|mint:P81877|rcsb pdb:6IWV|rcsb pdb:6TYD|dip:DIP-29459N refseq:NP_001124306.1|refseq:NP_001281.1|dip:DIP-24262N|dip:DIP-41215N|ensembl:ENSG00000169744(gene)|ensembl:ENST00000304523(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001942"(hair follicle development)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005886"(plasma membrane)|go:"GO:0007399"(nervous system development)|go:"GO:0010669"(epithelial structure maintenance)|go:"GO:0019899"(enzyme binding)|go:"GO:0030274"(LIM domain binding)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031252"(cell leading edge)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0043549"(regulation of kinase activity)|go:"GO:0044089"(positive regulation of cellular component biogenesis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|interpro:IPR029005|interpro:IPR030174|interpro:IPR041363 psi-mi:"MI:0465"(dip) - crc64:E86387BA027F383A full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/05 2017/08/10 rogid:CMmZPTurp1G6Y2q7GP/pTMlFM549606 rogid:3p/spcR1ariBlpLJczJxP5Mfi9w9606 rigid:BEhSM4cpGThCsZ6IyREbgsz1uZA false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P30626 uniprotkb:P30626 intact:EBI-750459|uniprotkb:D6W5Q0|intact:EBI-2623494|uniprotkb:A8MTH6|uniprotkb:B4DKK2|ensembl:ENSP00000265729 intact:EBI-750459|uniprotkb:D6W5Q0|intact:EBI-2623494|uniprotkb:A8MTH6|uniprotkb:B4DKK2|ensembl:ENSP00000265729 psi-mi:sorcn_human(display_long)|uniprotkb:22 kDa protein(gene name synonym)|uniprotkb:CP-22(gene name synonym)|uniprotkb:V19(gene name synonym)|uniprotkb:SRI(gene name)|psi-mi:SRI(display_short) psi-mi:sorcn_human(display_long)|uniprotkb:22 kDa protein(gene name synonym)|uniprotkb:CP-22(gene name synonym)|uniprotkb:V19(gene name synonym)|uniprotkb:SRI(gene name)|psi-mi:SRI(display_short) psi-mi:"MI:0018"(two hybrid) DeGrado-Warren et al. (2008) pubmed:18330356|imex:IM-8752 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15690652|dip:DIP-58845E|imex:IM-8752-48 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_944490.1|refseq:NP_003121.1|refseq:NP_001243820.1|refseq:NP_001243821.1|dip:DIP-40970N|ensembl:ENSG00000075142(gene)|ensembl:ENST00000265729(transcript)|go:"GO:0001508"(action potential)|go:"GO:0002020"(protease binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006880"(intracellular sequestering of iron ion)|go:"GO:0006942"(regulation of striated muscle contraction)|go:"GO:0007165"(signal transduction)|go:"GO:0007507"(heart development)|go:"GO:0007517"(muscle organ development)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0010459"(negative regulation of heart rate)|go:"GO:0030315"(T-tubule)|go:"GO:0033017"(sarcoplasmic reticulum membrane)|go:"GO:0035774"(positive regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0042802"(identical protein binding)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0043679"(axon terminus)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044326"(dendritic spine neck)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051281"(positive regulation of release of sequestered calcium ion into cytosol)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0055118"(negative regulation of cardiac muscle contraction)|go:"GO:0060315"(negative regulation of ryanodine-sensitive calcium-release channel activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0086004"(regulation of cardiac muscle cell contraction)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1901077"(regulation of relaxation of muscle)|go:"GO:1901841"(regulation of high voltage-gated calcium channel activity)|go:"GO:0010649"(regulation of cell communication by electrical coupling)|go:"GO:0010880"(regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0016020"(membrane)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0030018"(Z disc)|rcsb pdb:2JC2|rcsb pdb:4U8D|rcsb pdb:4UPG|rcsb pdb:4USL|rcsb pdb:5MRA|reactome:R-HSA-2672351|reactome:R-HSA-418359|reactome:R-HSA-425561|reactome:R-HSA-5578775|reactome:R-HSA-936837|go:"GO:1901844"(regulation of cell communication by electrical coupling involved in cardiac conduction)|go:"GO:2000678"(negative regulation of transcription regulatory region DNA binding)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|mint:P30626|rcsb pdb:1JUO refseq:NP_944490.1|refseq:NP_003121.1|refseq:NP_001243820.1|refseq:NP_001243821.1|dip:DIP-40970N|ensembl:ENSG00000075142(gene)|ensembl:ENST00000265729(transcript)|go:"GO:0001508"(action potential)|go:"GO:0002020"(protease binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006880"(intracellular sequestering of iron ion)|go:"GO:0006942"(regulation of striated muscle contraction)|go:"GO:0007165"(signal transduction)|go:"GO:0007507"(heart development)|go:"GO:0007517"(muscle organ development)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0010459"(negative regulation of heart rate)|go:"GO:0030315"(T-tubule)|go:"GO:0033017"(sarcoplasmic reticulum membrane)|go:"GO:0035774"(positive regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0042802"(identical protein binding)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0043679"(axon terminus)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044326"(dendritic spine neck)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051281"(positive regulation of release of sequestered calcium ion into cytosol)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0055118"(negative regulation of cardiac muscle contraction)|go:"GO:0060315"(negative regulation of ryanodine-sensitive calcium-release channel activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0086004"(regulation of cardiac muscle cell contraction)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1901077"(regulation of relaxation of muscle)|go:"GO:1901841"(regulation of high voltage-gated calcium channel activity)|go:"GO:0010649"(regulation of cell communication by electrical coupling)|go:"GO:0010880"(regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0016020"(membrane)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0030018"(Z disc)|rcsb pdb:2JC2|rcsb pdb:4U8D|rcsb pdb:4UPG|rcsb pdb:4USL|rcsb pdb:5MRA|reactome:R-HSA-2672351|reactome:R-HSA-418359|reactome:R-HSA-425561|reactome:R-HSA-5578775|reactome:R-HSA-936837|go:"GO:1901844"(regulation of cell communication by electrical coupling involved in cardiac conduction)|go:"GO:2000678"(negative regulation of transcription regulatory region DNA binding)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|mint:P30626|rcsb pdb:1JUO psi-mi:"MI:0465"(dip) crc64:A4829C7650A5E3FA crc64:A4829C7650A5E3FA full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/05 2017/08/10 rogid:upE31IMimaotkgnYa7HYr7EYAxc9606 rogid:upE31IMimaotkgnYa7HYr7EYAxc9606 rigid:yuChTBuj+PCNsWydceSY1GWliYs false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q16181 uniprotkb:Q99719 intact:EBI-2009373|uniprotkb:Q52M76|uniprotkb:Q6NX50|ensembl:ENSP00000381992 intact:EBI-373345|uniprotkb:O15251|uniprotkb:Q96MY5|ensembl:ENSP00000391311 psi-mi:sept7_human(display_long)|uniprotkb:SEPTIN7(gene name)|psi-mi:SEPTIN7(display_short)|uniprotkb:CDC10(gene name synonym)|uniprotkb:CDC10 protein homolog(gene name synonym)|uniprotkb:SEPT7(gene name synonym) psi-mi:sept5_human(display_long)|uniprotkb:SEPTIN5(gene name)|psi-mi:SEPTIN5(display_short)|uniprotkb:Cell division control-related protein 1(gene name synonym)|uniprotkb:PNUTL1(gene name synonym)|uniprotkb:Peanut-like protein 1(gene name synonym)|uniprotkb:SEPT5(gene name synonym) psi-mi:"MI:0018"(two hybrid) DeGrado-Warren et al. (2008) pubmed:18330356|imex:IM-8752 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15690636|dip:DIP-58843E|imex:IM-8752-46 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001779.3|dip:DIP-47093N|ensembl:ENSG00000122545(gene)|ensembl:ENST00000399034(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0001725"(stress fiber)|go:"GO:0003924"(GTPase activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005930"(axoneme)|go:"GO:0005940"(septin ring)|go:"GO:0007283"(spermatogenesis)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016476"(regulation of embryonic cell shape)|go:"GO:0030154"(cell differentiation)|go:"GO:0030496"(midbody)|go:"GO:0031105"(septin complex)|go:"GO:0032153"(cell division site)|go:"GO:0032154"(cleavage furrow)|go:"GO:0034613"(cellular protein localization)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097227"(sperm annulus)|go:"GO:0097730"(non-motile cilium)|go:"GO:1902857"(positive regulation of non-motile cilium assembly)|interpro:IPR008115(Septin 7)|interpro:IPR016491(Septin)|interpro:IPR027417|interpro:IPR030379|rcsb pdb:2QAG|rcsb pdb:3T5D|rcsb pdb:3TW4|rcsb pdb:6N0B|rcsb pdb:6N12|rcsb pdb:6UQQ|reactome:R-HSA-5687128 refseq:NP_002679.2|refseq:NP_001009939.1|ensembl:ENSG00000184702(gene)|ensembl:ENST00000455784(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005940"(septin ring)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016080"(synaptic vesicle targeting)|go:"GO:0017157"(regulation of exocytosis)|go:"GO:0030534"(adult behavior)|go:"GO:0031105"(septin complex)|go:"GO:0032153"(cell division site)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035176"(social behavior)|go:"GO:0042802"(identical protein binding)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|interpro:IPR016491(Septin)|interpro:IPR027417|interpro:IPR030379|interpro:IPR030647|mint:Q99719|rcsb pdb:6WCU|dip:DIP-31201N psi-mi:"MI:0465"(dip) - crc64:47054765DEA10D33 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/05 2017/08/10 rogid:CweIjGLXC7eubvKR7vkkihEkcHg9606 rogid:kubhD1O+WmJeDWTlX+rcjpP9yRc9606 rigid:FVWZpoxOPgaN4VYzHkBdDyYBAfI false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9BWW4 uniprotkb:O43679 intact:EBI-2902395|uniprotkb:A8K0A9|uniprotkb:Q5T860|uniprotkb:Q5T861|uniprotkb:Q9BTM0|uniprotkb:Q9BWW3|ensembl:ENSP00000479674 intact:EBI-2865580|uniprotkb:O75480|uniprotkb:O60619|ensembl:ENSP00000306772 psi-mi:ssbp3_human(display_long)|uniprotkb:SSBP3(gene name)|psi-mi:SSBP3(display_short)|uniprotkb:SSDP(gene name synonym)|uniprotkb:SSDP1(gene name synonym)|uniprotkb:Sequence-specific single-stranded-DNA-binding protein(gene name synonym) psi-mi:ldb2_human(display_long)|uniprotkb:LDB2(gene name)|psi-mi:LDB2(display_short)|uniprotkb:CLIM1(gene name synonym)|uniprotkb:Carboxyl-terminal LIM domain-binding protein 1(gene name synonym)|uniprotkb:LIM domain-binding factor CLIM1(gene name synonym) psi-mi:"MI:0018"(two hybrid) DeGrado-Warren et al. (2008) pubmed:18330356|imex:IM-8752 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15690684|dip:DIP-58831E|imex:IM-8752-50 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001009955.1|refseq:NP_060540.2|refseq:NP_663768.1|dip:DIP-48897N|ensembl:ENSG00000157216(gene)|ensembl:ENST00000610401(transcript)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR006594(LisH dimerisation motif)|interpro:IPR008116(Sequence-specific single-strand DNA-binding protein)|mint:Q9BWW4 refseq:NP_001124306.1|refseq:NP_001281.1|dip:DIP-24262N|dip:DIP-41215N|ensembl:ENSG00000169744(gene)|ensembl:ENST00000304523(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001942"(hair follicle development)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005886"(plasma membrane)|go:"GO:0007399"(nervous system development)|go:"GO:0010669"(epithelial structure maintenance)|go:"GO:0019899"(enzyme binding)|go:"GO:0030274"(LIM domain binding)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031252"(cell leading edge)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0043549"(regulation of kinase activity)|go:"GO:0044089"(positive regulation of cellular component biogenesis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|interpro:IPR029005|interpro:IPR030174|interpro:IPR041363 psi-mi:"MI:0465"(dip) crc64:DBBB169D4EE10536 crc64:E86387BA027F383A full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/05 2017/08/10 rogid:GD7FO6kR/5WawTNP0MaDcmIf7f49606 rogid:3p/spcR1ariBlpLJczJxP5Mfi9w9606 rigid:L6bX54KnnkVH6crqEK3LaMbatMk false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P04792 uniprotkb:P02511 intact:EBI-352682|uniprotkb:Q6FI47|uniprotkb:Q96C20|uniprotkb:Q96EI7|uniprotkb:Q9UC34|uniprotkb:Q9UC35|uniprotkb:Q9UC36|uniprotkb:Q9UC31|ensembl:ENSP00000248553|uniprotkb:B2R4N8 intact:EBI-739060|uniprotkb:O43416|uniprotkb:B0YIX0|uniprotkb:Q9UC37|uniprotkb:Q9UC38|uniprotkb:Q9UC39|uniprotkb:Q9UC40|uniprotkb:Q9UC41|ensembl:ENSP00000227251|ensembl:ENSP00000433560|ensembl:ENSP00000434247|ensembl:ENSP00000435931|ensembl:ENSP00000436051|ensembl:ENSP00000436089|ensembl:ENSP00000437149|ensembl:ENSP00000483554|ensembl:ENSP00000498735|ensembl:ENSP00000499082 psi-mi:hspb1_human(display_long)|uniprotkb:HSPB1(gene name)|psi-mi:HSPB1(display_short)|uniprotkb:HSP27(gene name synonym)|uniprotkb:HSP28(gene name synonym)|uniprotkb:Heat shock 27 kDa protein(gene name synonym)|uniprotkb:Stress-responsive protein 27(gene name synonym)|uniprotkb:Estrogen-regulated 24 kDa protein(gene name synonym)|uniprotkb:28 kDa heat shock protein(gene name synonym) psi-mi:cryab_human(display_long)|uniprotkb:CRYAB(gene name)|psi-mi:CRYAB(display_short)|uniprotkb:CRYA2(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-27(gene name synonym)|uniprotkb:"Alpha(B)-crystallin"(gene name synonym)|uniprotkb:Rosenthal fiber component(gene name synonym)|uniprotkb:Heat shock protein beta-5(gene name synonym)|uniprotkb:HSPB5(gene name synonym) psi-mi:"MI:0018"(two hybrid) DeGrado-Warren et al. (2008) pubmed:18330356|imex:IM-8752 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15690668|dip:DIP-88122E|imex:IM-8752-72 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001531.1|ensembl:ENSG00000106211(gene)|ensembl:ENST00000248553(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0001895"(retina homeostasis)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0003723"(RNA binding)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008426"(protein kinase C inhibitor activity)|go:"GO:0009615"(response to virus)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030018"(Z disc)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035924"(cellular response to vascular endothelial growth factor stimulus)|go:"GO:0038033"(positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070527"(platelet aggregation)|go:"GO:0099641"(anterograde axonal protein transport)|go:"GO:1902176"(negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1904115"(axon cytoplasm)|go:"GO:2001028"(positive regulation of endothelial cell chemotaxis)|interpro:IPR001436(Alpha crystallin/Heat shock protein)|interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR037876|mint:P04792|rcsb pdb:2N3J|rcsb pdb:3Q9P|rcsb pdb:3Q9Q|rcsb pdb:4MJH|rcsb pdb:6DV5|rcsb pdb:6GJH|reactome:R-HSA-4420097|reactome:R-HSA-450408|reactome:R-HSA-5687128|reactome:R-HSA-9009391|dip:DIP-412N ensembl:ENSG00000109846(gene)|ensembl:ENST00000227251(transcript)|ensembl:ENST00000526180(transcript)|ensembl:ENST00000527899(transcript)|ensembl:ENST00000527950(transcript)|ensembl:ENST00000531198(transcript)|ensembl:ENST00000533475(transcript)|ensembl:ENST00000533879(transcript)|ensembl:ENST00000616970(transcript)|ensembl:ENST00000650687(transcript)|ensembl:ENST00000651164(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001666"(response to hypoxia)|go:"GO:0002088"(lens development in camera-type eye)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0006936"(muscle contraction)|go:"GO:0007021"(tubulin complex assembly)|go:"GO:0007517"(muscle organ development)|go:"GO:0008017"(microtubule binding)|go:"GO:0009986"(cell surface)|go:"GO:0010259"(multicellular organism aging)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010941"(regulation of cell death)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030018"(Z disc)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030424"(axon)|go:"GO:0031109"(microtubule polymerization or depolymerization)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031430"(M band)|go:"GO:0032355"(response to estradiol)|go:"GO:0032387"(negative regulation of intracellular transport)|go:"GO:0032432"(actin filament bundle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043197"(dendritic spine)|go:"GO:0043204"(perikaryon)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051403"(stress-activated MAPK cascade)|go:"GO:0060561"(apoptotic process involved in morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0097060"(synaptic membrane)|go:"GO:0097512"(cardiac myofibril)|go:"GO:1905907"(negative regulation of amyloid fibril formation)|go:"GO:2000378"(negative regulation of reactive oxygen species metabolic process)|interpro:IPR001436(Alpha crystallin/Heat shock protein)|interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR003090(Alpha-crystallin, N-terminal)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR037882|mint:P02511|rcsb pdb:2KLR|rcsb pdb:2N0K|rcsb pdb:2WJ7|rcsb pdb:2Y1Y|rcsb pdb:2Y1Z|rcsb pdb:2YGD|rcsb pdb:3J07|rcsb pdb:2Y22|rcsb pdb:3L1G|rcsb pdb:3SGM|rcsb pdb:3SGN|rcsb pdb:3SGO|rcsb pdb:3SGP|rcsb pdb:3SGR|rcsb pdb:3SGS|rcsb pdb:4M5S|rcsb pdb:4M5T|rcsb pdb:5VVV|rcsb pdb:6BP9|reactome:R-HSA-3371571|refseq:NP_001876.1|refseq:XP_011540910.1|refseq:NP_001276736.1|refseq:NP_001276737.1|dip:DIP-35017N psi-mi:"MI:0465"(dip) crc64:1B4DC44A6F6606D5 crc64:AE08BED46B7849CB full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/05 2017/08/10 rogid:vrDXIdzP30aHSDLHOh2D4x54eJY9606 rogid:495Z42oQhkAUdADrAEOKIC5oICo9606 rigid:HlIost5vRGNZhOzHD7XSsVsRheE false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O15212 uniprotkb:Q96EK4 intact:EBI-356973|ensembl:ENSP00000363734|ensembl:ENSP00000363735|ensembl:ENSP00000363738|ensembl:ENSP00000372694|ensembl:ENSP00000378563|ensembl:ENSP00000382314|ensembl:ENSP00000382316|ensembl:ENSP00000395462|ensembl:ENSP00000398171|ensembl:ENSP00000400152|ensembl:ENSP00000402212|ensembl:ENSP00000402553|ensembl:ENSP00000403771|ensembl:ENSP00000404773|ensembl:ENSP00000412319|ensembl:ENSP00000415678|ensembl:ENSP00000447540|ensembl:ENSP00000448607|ensembl:ENSP00000448784|ensembl:ENSP00000449925 intact:EBI-1790529|uniprotkb:O94795|uniprotkb:A8K002|uniprotkb:A4UCT5|ensembl:ENSP00000304689 psi-mi:pfd6_human(display_long)|uniprotkb:PFDN6(gene name)|psi-mi:PFDN6(display_short)|uniprotkb:HKE2(gene name synonym)|uniprotkb:PFD6(gene name synonym)|uniprotkb:Protein Ke2(gene name synonym) psi-mi:tha11_human(display_long)|uniprotkb:THAP11(gene name)|psi-mi:THAP11(display_short)|uniprotkb:HRIHFB2206(orf name) psi-mi:"MI:0018"(two hybrid) DeGrado-Warren et al. (2008) pubmed:18330356|imex:IM-8752 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15690700|dip:DIP-58851E|imex:IM-8752-52 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001172110.1|refseq:NP_055075.1|refseq:NP_001252524.1|refseq:NP_001252525.1|dip:DIP-50304N|ensembl:ENSG00000204220(gene)|ensembl:ENSG00000206283(gene)|ensembl:ENSG00000224782(gene)|ensembl:ENSG00000235692(gene)|ensembl:ENSG00000237335(gene)|ensembl:ENST00000374606(transcript)|ensembl:ENST00000374607(transcript)|ensembl:ENST00000374610(transcript)|ensembl:ENST00000383207(transcript)|ensembl:ENST00000395131(transcript)|ensembl:ENST00000399383(transcript)|ensembl:ENST00000399385(transcript)|ensembl:ENST00000412289(transcript)|ensembl:ENST00000425878(transcript)|ensembl:ENST00000431830(transcript)|ensembl:ENST00000432391(transcript)|ensembl:ENST00000442285(transcript)|ensembl:ENST00000445559(transcript)|ensembl:ENST00000448594(transcript)|ensembl:ENST00000451970(transcript)|ensembl:ENST00000452658(transcript)|ensembl:ENST00000547641(transcript)|ensembl:ENST00000547952(transcript)|ensembl:ENST00000548040(transcript)|ensembl:ENST00000552711(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006457"(protein folding)|go:"GO:0016272"(prefoldin complex)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:1905907"(negative regulation of amyloid fibril formation)|interpro:IPR002777(Prefoldin beta-like)|interpro:IPR009053(Prefoldin)|mint:O15212|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|reactome:R-HSA-389957 refseq:NP_065190.2|dip:DIP-46732N|ensembl:ENSP00000304689|ensembl:ENSG00000168286(gene)|ensembl:ENST00000303596(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|interpro:IPR006612(Zinc finger, C2CH-type)|rcsb pdb:2LAU|rcsb pdb:5AJS psi-mi:"MI:0465"(dip) crc64:8F138EAAE512A312 crc64:25235D20CB54D8C2 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/05 2017/08/10 rogid:t7Z68vuvmprxLIGDh4JhqCGvX+A9606 rogid:qzl6RN2xlTuDBruwyKLyDTNRCKE9606 rigid:scsp3qYOFCDfy+h5LV2dJicd7ug false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q96GS4 uniprotkb:P47712 intact:EBI-10193358|uniprotkb:Q9NXW8|uniprotkb:Q53HS4|ensembl:ENSP00000373669 intact:EBI-1044090|uniprotkb:Q29R80|ensembl:ENSP00000356436|uniprotkb:B1AKG4 psi-mi:borc6_human(display_long)|uniprotkb:BORCS6(gene name)|psi-mi:BORCS6(display_short)|uniprotkb:C17orf59(gene name synonym)|uniprotkb:Lysosome-dispersing protein(gene name synonym) psi-mi:pa24a_human(display_long)|uniprotkb:PLA2G4A(gene name)|psi-mi:PLA2G4A(display_short)|uniprotkb:CPLA2(gene name synonym)|uniprotkb:PLA2G4(gene name synonym)|uniprotkb:Phospholipase A2 group IVA(gene name synonym) psi-mi:"MI:0018"(two hybrid) DeGrado-Warren et al. (2008) pubmed:18330356|imex:IM-8752 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15690716|dip:DIP-58835E|imex:IM-8752-92 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060092.2|ensembl:ENSG00000196544(gene)|ensembl:ENST00000389017(transcript)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0032418"(lysosome localization)|go:"GO:0042802"(identical protein binding)|go:"GO:0099078"(BORC complex)|interpro:IPR019314|dip:DIP-29465N refseq:NP_077734.1|go:"GO:0102567"|go:"GO:0102568"|go:"GO:1902387"(ceramide 1-phosphate binding)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR002642(Lysophospholipase, catalytic region)|interpro:IPR016035(Acyl transferase/acyl hydrolase/lysophospholipase)|interpro:IPR035892|interpro:IPR041847|rcsb pdb:1BCI|rcsb pdb:1CJY|rcsb pdb:1RLW|reactome:R-HSA-111995|reactome:R-HSA-1482788|reactome:R-HSA-1482798|reactome:R-HSA-1482801|reactome:R-HSA-1482839|reactome:R-HSA-1482922|reactome:R-HSA-1482925|reactome:R-HSA-1483115|reactome:R-HSA-1483166|reactome:R-HSA-2142753|reactome:R-HSA-418592|reactome:R-HSA-432142|reactome:R-HSA-6811436|ensembl:ENSG00000116711(gene)|ensembl:ENST00000367466(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001516"(prostaglandin biosynthetic process)|go:"GO:0002827"(positive regulation of T-helper 1 type immune response)|go:"GO:0004622"(lysophospholipase activity)|go:"GO:0004623"(phospholipase A2 activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006071"(glycerol metabolic process)|go:"GO:0006640"(monoacylglycerol biosynthetic process)|go:"GO:0006663"(platelet activating factor biosynthetic process)|go:"GO:0008374"(O-acyltransferase activity)|go:"GO:0010314"(phosphatidylinositol-5-phosphate binding)|go:"GO:0010572"(positive regulation of platelet activation)|go:"GO:0019369"(arachidonic acid metabolic process)|go:"GO:0019370"(leukotriene biosynthetic process)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0032308"(positive regulation of prostaglandin secretion)|go:"GO:0034478"(phosphatidylglycerol catabolic process)|go:"GO:0034638"(phosphatidylcholine catabolic process)|go:"GO:0036151"(phosphatidylcholine acyl-chain remodeling)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043032"(positive regulation of macrophage activation)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046475"(glycerophospholipid catabolic process)|go:"GO:0047498"(calcium-dependent phospholipase A2 activity)|go:"GO:0047499"(calcium-independent phospholipase A2 activity)|go:"GO:0050482"(arachidonic acid secretion)|go:"GO:0070273"(phosphatidylinositol-4-phosphate binding)|go:"GO:0071236"(cellular response to antibiotic)|go:"GO:0102545"(phosphatidyl phospholipase B activity)|go:"GO:0006690"(icosanoid metabolic process)|refseq:NP_001298122.1|refseq:XP_011507944.1|dip:DIP-40991N psi-mi:"MI:0465"(dip) crc64:BBA89770528FA9E9 crc64:EE71CA0EBE617856 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/05 2017/08/10 rogid:ZAfDrF1Nb8RnQqg0T50TaEJ3Xp09606 rogid:D/yM7EFWP6xaMQ//7wutJS5D3jw9606 rigid:hyS8crxOoqYmdXMK7UtT4nYgYwk false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9BWW4 uniprotkb:O43679 intact:EBI-2902395|uniprotkb:A8K0A9|uniprotkb:Q5T860|uniprotkb:Q5T861|uniprotkb:Q9BTM0|uniprotkb:Q9BWW3|ensembl:ENSP00000479674 intact:EBI-2865580|uniprotkb:O75480|uniprotkb:O60619|ensembl:ENSP00000306772 psi-mi:ssbp3_human(display_long)|uniprotkb:SSBP3(gene name)|psi-mi:SSBP3(display_short)|uniprotkb:SSDP(gene name synonym)|uniprotkb:SSDP1(gene name synonym)|uniprotkb:Sequence-specific single-stranded-DNA-binding protein(gene name synonym) psi-mi:ldb2_human(display_long)|uniprotkb:LDB2(gene name)|psi-mi:LDB2(display_short)|uniprotkb:CLIM1(gene name synonym)|uniprotkb:Carboxyl-terminal LIM domain-binding protein 1(gene name synonym)|uniprotkb:LIM domain-binding factor CLIM1(gene name synonym) psi-mi:"MI:0018"(two hybrid) DeGrado-Warren et al. (2008) pubmed:18330356|imex:IM-8752 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15690732|imex:IM-8752-38|dip:DIP-58833E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001009955.1|refseq:NP_060540.2|refseq:NP_663768.1|dip:DIP-48897N|ensembl:ENSG00000157216(gene)|ensembl:ENST00000610401(transcript)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR006594(LisH dimerisation motif)|interpro:IPR008116(Sequence-specific single-strand DNA-binding protein)|mint:Q9BWW4 refseq:NP_001124306.1|refseq:NP_001281.1|dip:DIP-24262N|dip:DIP-41215N|ensembl:ENSG00000169744(gene)|ensembl:ENST00000304523(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001942"(hair follicle development)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005886"(plasma membrane)|go:"GO:0007399"(nervous system development)|go:"GO:0010669"(epithelial structure maintenance)|go:"GO:0019899"(enzyme binding)|go:"GO:0030274"(LIM domain binding)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031252"(cell leading edge)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0043549"(regulation of kinase activity)|go:"GO:0044089"(positive regulation of cellular component biogenesis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|interpro:IPR029005|interpro:IPR030174|interpro:IPR041363 psi-mi:"MI:0465"(dip) crc64:DBBB169D4EE10536 crc64:E86387BA027F383A full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/05 2017/08/10 rogid:GD7FO6kR/5WawTNP0MaDcmIf7f49606 rogid:3p/spcR1ariBlpLJczJxP5Mfi9w9606 rigid:L6bX54KnnkVH6crqEK3LaMbatMk false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q16520 uniprotkb:P35638 intact:EBI-749503|ensembl:ENSP00000286639 intact:EBI-742651|ensembl:ENSP00000340671|ensembl:ENSP00000447188|ensembl:ENSP00000494844|uniprotkb:F8VS99 psi-mi:batf_human(display_long)|uniprotkb:SF-HT-activated gene 2 protein(gene name synonym)|uniprotkb:BATF(gene name)|psi-mi:BATF(display_short)|uniprotkb:B-cell-activating transcription factor(gene name synonym) psi-mi:ddit3_human(display_long)|uniprotkb:CHOP10(gene name synonym)|uniprotkb:C/EBP-homologous protein(gene name synonym)|uniprotkb:DDIT3(gene name)|psi-mi:DDIT3(display_short)|uniprotkb:CHOP(gene name synonym)|uniprotkb:GADD153(gene name synonym)|uniprotkb:Growth arrest and DNA damage-inducible protein GADD153(gene name synonym)|uniprotkb:C/EBP-homologous protein 10(gene name synonym)|uniprotkb:C/EBP zeta(gene name synonym)|uniprotkb:CCAAT/enhancer-binding protein homologous protein(gene name synonym) psi-mi:"MI:0018"(two hybrid) DeGrado-Warren et al. (2008) pubmed:18330356|imex:IM-8752 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15690748|imex:IM-8752-39|dip:DIP-58817E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006390.1|dip:DIP-52482N|ensembl:ENSG00000156127(gene)|ensembl:ENST00000286639(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0002320"(lymphoid progenitor cell differentiation)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0030330"(DNA damage response, signal transduction by p53 class mediator)|go:"GO:0042832"(defense response to protozoan)|go:"GO:0043011"(myeloid dendritic cell differentiation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045064"(T-helper 2 cell differentiation)|go:"GO:0045190"(isotype switching)|go:"GO:0060218"(hematopoietic stem cell differentiation)|go:"GO:0072539"(T-helper 17 cell differentiation)|go:"GO:0072540"(T-helper 17 cell lineage commitment)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000837(Fos transforming protein)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029820|mint:Q16520|reactome:R-HSA-6785807 refseq:NP_001181986.1|refseq:NP_004074.2|refseq:NP_001181982.1|refseq:NP_001181983.1|refseq:NP_001181984.1|ensembl:ENSG00000175197(gene)|go:"GO:0001955"(blood vessel maturation)|ensembl:ENST00000346473(transcript)|ensembl:ENST00000547303(transcript)|ensembl:ENST00000623876(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003677"(DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032792"(negative regulation of CREB transcription factor activity)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0036488"(CHOP-C/EBP complex)|go:"GO:0036499"(PERK-mediated unfolded protein response)|go:"GO:0036500"(ATF6-mediated unfolded protein response)|go:"GO:0042594"(response to starvation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043522"(leucine zipper domain binding)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0032713"(negative regulation of interleukin-4 production)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0006983"(ER overload response)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0007049"(cell cycle)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008140"(cAMP response element binding protein binding)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0005737"(cytoplasm)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0005770"(late endosome)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032689"(negative regulation of interferon-gamma production)|go:"GO:0032700"(negative regulation of interleukin-17 production)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0051209"(release of sequestered calcium ion into cytosol)|go:"GO:0051898"(negative regulation of protein kinase B signaling)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0072655"(establishment of protein localization to mitochondrion)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0120163"(negative regulation of cold-induced thermogenesis)|go:"GO:0140416"(transcription regulator inhibitor activity)|go:"GO:1902237"(positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903026"(negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990442"(intrinsic apoptotic signaling pathway in response to nitrosative stress)|go:"GO:1990617"(CHOP-ATF4 complex)|go:"GO:1990622"(CHOP-ATF3 complex)|go:"GO:2000016"(negative regulation of determination of dorsal identity)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR016670(DNA damage-inducible transcript 3)|mint:P35638|reactome:R-HSA-380994|reactome:R-HSA-381183|reactome:R-HSA-9614657|reactome:R-HSA-9633012|reactome:R-HSA-9648895|go:"GO:0043618"(regulation of transcription from RNA polymerase II promoter in response to stress)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045662"(negative regulation of myoblast differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|dip:DIP-41589N psi-mi:"MI:0465"(dip) crc64:7FD633C6F1963DF4 crc64:31905293FB1FBBE2 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/05 2017/08/10 rogid:rZdG+kauGaMPmB9bp0fV2W0t4lk9606 rogid:xyMsMwPwid+S2IYb3H0K0pnUc309606 rigid:O15HEKxIOAqh5ogx4lDB6tLGN9s false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O14908 uniprotkb:P35638 intact:EBI-373132|uniprotkb:Q9BTC9|uniprotkb:A8MZG3|uniprotkb:A8K4I3|ensembl:ENSP00000340698|ensembl:ENSP00000376753|ensembl:ENSP00000466747 intact:EBI-742651|ensembl:ENSP00000340671|ensembl:ENSP00000447188|ensembl:ENSP00000494844|uniprotkb:F8VS99 psi-mi:gipc1_human(display_long)|uniprotkb:C19orf3(gene name synonym)|uniprotkb:GIPC(gene name synonym)|uniprotkb:GIPC1(gene name)|psi-mi:GIPC1(display_short)|uniprotkb:RGS19IP1(gene name synonym)|uniprotkb:RGS19-interacting protein 1(gene name synonym)|uniprotkb:GAIP C-terminus-interacting protein(gene name synonym)|uniprotkb:RGS-GAIP-interacting protein(gene name synonym)|uniprotkb:Tax interaction protein 2(gene name synonym)|uniprotkb:Synectin(gene name synonym) psi-mi:ddit3_human(display_long)|uniprotkb:CHOP10(gene name synonym)|uniprotkb:C/EBP-homologous protein(gene name synonym)|uniprotkb:DDIT3(gene name)|psi-mi:DDIT3(display_short)|uniprotkb:CHOP(gene name synonym)|uniprotkb:GADD153(gene name synonym)|uniprotkb:Growth arrest and DNA damage-inducible protein GADD153(gene name synonym)|uniprotkb:C/EBP-homologous protein 10(gene name synonym)|uniprotkb:C/EBP zeta(gene name synonym)|uniprotkb:CCAAT/enhancer-binding protein homologous protein(gene name synonym) psi-mi:"MI:0018"(two hybrid) DeGrado-Warren et al. (2008) pubmed:18330356|imex:IM-8752 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15690764|imex:IM-8752-40|dip:DIP-58819E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005707.1|refseq:NP_974197.1|refseq:NP_974199.1|refseq:NP_974198.1|refseq:NP_974223.1|ensembl:ENSG00000123159(gene)|ensembl:ENST00000345425(transcript)|ensembl:ENST00000393033(transcript)|ensembl:ENST00000586027(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005903"(brush border)|go:"GO:0005938"(cell cortex)|go:"GO:0006605"(protein targeting)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0012506"(vesicle membrane)|go:"GO:0014047"(glutamate secretion)|go:"GO:0016020"(membrane)|go:"GO:0017022"(myosin binding)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030511"(positive regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032467"(positive regulation of cytokinesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043197"(dendritic spine)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043542"(endothelial cell migration)|go:"GO:0045296"(cadherin binding)|go:"GO:0048023"(positive regulation of melanin biosynthetic process)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098761"(cellular response to interleukin-7)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR017379(Uncharacterised conserved protein UCP038083, PDZ)|interpro:IPR036034|refseq:XP_016881636.1|refseq:XP_016881637.1|dip:DIP-31142N refseq:NP_001181986.1|refseq:NP_004074.2|refseq:NP_001181982.1|refseq:NP_001181983.1|refseq:NP_001181984.1|ensembl:ENSG00000175197(gene)|go:"GO:0001955"(blood vessel maturation)|ensembl:ENST00000346473(transcript)|ensembl:ENST00000547303(transcript)|ensembl:ENST00000623876(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003677"(DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032792"(negative regulation of CREB transcription factor activity)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0036488"(CHOP-C/EBP complex)|go:"GO:0036499"(PERK-mediated unfolded protein response)|go:"GO:0036500"(ATF6-mediated unfolded protein response)|go:"GO:0042594"(response to starvation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043522"(leucine zipper domain binding)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0032713"(negative regulation of interleukin-4 production)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0006983"(ER overload response)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0007049"(cell cycle)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008140"(cAMP response element binding protein binding)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0005737"(cytoplasm)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0005770"(late endosome)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032689"(negative regulation of interferon-gamma production)|go:"GO:0032700"(negative regulation of interleukin-17 production)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0051209"(release of sequestered calcium ion into cytosol)|go:"GO:0051898"(negative regulation of protein kinase B signaling)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0072655"(establishment of protein localization to mitochondrion)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0120163"(negative regulation of cold-induced thermogenesis)|go:"GO:0140416"(transcription regulator inhibitor activity)|go:"GO:1902237"(positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903026"(negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990442"(intrinsic apoptotic signaling pathway in response to nitrosative stress)|go:"GO:1990617"(CHOP-ATF4 complex)|go:"GO:1990622"(CHOP-ATF3 complex)|go:"GO:2000016"(negative regulation of determination of dorsal identity)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR016670(DNA damage-inducible transcript 3)|mint:P35638|reactome:R-HSA-380994|reactome:R-HSA-381183|reactome:R-HSA-9614657|reactome:R-HSA-9633012|reactome:R-HSA-9648895|go:"GO:0043618"(regulation of transcription from RNA polymerase II promoter in response to stress)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045662"(negative regulation of myoblast differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|dip:DIP-41589N psi-mi:"MI:0465"(dip) - crc64:31905293FB1FBBE2 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/05 2017/08/10 rogid:3lbsiL3bZ/h3ISEr/ryTN7FgbQI9606 rogid:xyMsMwPwid+S2IYb3H0K0pnUc309606 rigid:LH+sSsxx+38GwcXJQQUKZJKReCU false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9BUW7 uniprotkb:Q96EK4 intact:EBI-752084|uniprotkb:Q9Y3F7|uniprotkb:Q5SYV8|ensembl:ENSP00000362085 intact:EBI-1790529|uniprotkb:O94795|uniprotkb:A8K002|uniprotkb:A4UCT5|ensembl:ENSP00000304689 psi-mi:bbln_human(display_long)|uniprotkb:BBLN(gene name)|psi-mi:BBLN(display_short)|uniprotkb:C9orf16(gene name synonym)|uniprotkb:UPF0184 protein C9orf16(gene name synonym)|uniprotkb:EST00098(orf name) psi-mi:tha11_human(display_long)|uniprotkb:THAP11(gene name)|psi-mi:THAP11(display_short)|uniprotkb:HRIHFB2206(orf name) psi-mi:"MI:0018"(two hybrid) DeGrado-Warren et al. (2008) pubmed:18330356|imex:IM-8752 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15690780|imex:IM-8752-41|dip:DIP-58849E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_077017.1|dip:DIP-29481N|ensembl:ENSG00000171159(gene)|ensembl:ENST00000372994(transcript)|interpro:IPR005374(Protein of unknown function UPF0184) refseq:NP_065190.2|dip:DIP-46732N|ensembl:ENSP00000304689|ensembl:ENSG00000168286(gene)|ensembl:ENST00000303596(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|interpro:IPR006612(Zinc finger, C2CH-type)|rcsb pdb:2LAU|rcsb pdb:5AJS psi-mi:"MI:0465"(dip) crc64:EBE1D0AFAAD6DABB crc64:25235D20CB54D8C2 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/05 2017/08/10 rogid:O4VcHghk63gMrjyh5XKmkZovFZ49606 rogid:qzl6RN2xlTuDBruwyKLyDTNRCKE9606 rigid:XrOs7+WuIrvpYtSgVfNAZFmiWD0 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P02511 uniprotkb:P02511 intact:EBI-739060|uniprotkb:O43416|uniprotkb:B0YIX0|uniprotkb:Q9UC37|uniprotkb:Q9UC38|uniprotkb:Q9UC39|uniprotkb:Q9UC40|uniprotkb:Q9UC41|ensembl:ENSP00000227251|ensembl:ENSP00000433560|ensembl:ENSP00000434247|ensembl:ENSP00000435931|ensembl:ENSP00000436051|ensembl:ENSP00000436089|ensembl:ENSP00000437149|ensembl:ENSP00000483554|ensembl:ENSP00000498735|ensembl:ENSP00000499082 intact:EBI-739060|uniprotkb:O43416|uniprotkb:B0YIX0|uniprotkb:Q9UC37|uniprotkb:Q9UC38|uniprotkb:Q9UC39|uniprotkb:Q9UC40|uniprotkb:Q9UC41|ensembl:ENSP00000227251|ensembl:ENSP00000433560|ensembl:ENSP00000434247|ensembl:ENSP00000435931|ensembl:ENSP00000436051|ensembl:ENSP00000436089|ensembl:ENSP00000437149|ensembl:ENSP00000483554|ensembl:ENSP00000498735|ensembl:ENSP00000499082 psi-mi:cryab_human(display_long)|uniprotkb:CRYAB(gene name)|psi-mi:CRYAB(display_short)|uniprotkb:CRYA2(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-27(gene name synonym)|uniprotkb:"Alpha(B)-crystallin"(gene name synonym)|uniprotkb:Rosenthal fiber component(gene name synonym)|uniprotkb:Heat shock protein beta-5(gene name synonym)|uniprotkb:HSPB5(gene name synonym) psi-mi:cryab_human(display_long)|uniprotkb:CRYAB(gene name)|psi-mi:CRYAB(display_short)|uniprotkb:CRYA2(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-27(gene name synonym)|uniprotkb:"Alpha(B)-crystallin"(gene name synonym)|uniprotkb:Rosenthal fiber component(gene name synonym)|uniprotkb:Heat shock protein beta-5(gene name synonym)|uniprotkb:HSPB5(gene name synonym) psi-mi:"MI:0018"(two hybrid) DeGrado-Warren et al. (2008) pubmed:18330356|imex:IM-8752 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15690796|dip:DIP-186586E|imex:IM-8752-54 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000109846(gene)|ensembl:ENST00000227251(transcript)|ensembl:ENST00000526180(transcript)|ensembl:ENST00000527899(transcript)|ensembl:ENST00000527950(transcript)|ensembl:ENST00000531198(transcript)|ensembl:ENST00000533475(transcript)|ensembl:ENST00000533879(transcript)|ensembl:ENST00000616970(transcript)|ensembl:ENST00000650687(transcript)|ensembl:ENST00000651164(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001666"(response to hypoxia)|go:"GO:0002088"(lens development in camera-type eye)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0006936"(muscle contraction)|go:"GO:0007021"(tubulin complex assembly)|go:"GO:0007517"(muscle organ development)|go:"GO:0008017"(microtubule binding)|go:"GO:0009986"(cell surface)|go:"GO:0010259"(multicellular organism aging)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010941"(regulation of cell death)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030018"(Z disc)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030424"(axon)|go:"GO:0031109"(microtubule polymerization or depolymerization)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031430"(M band)|go:"GO:0032355"(response to estradiol)|go:"GO:0032387"(negative regulation of intracellular transport)|go:"GO:0032432"(actin filament bundle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043197"(dendritic spine)|go:"GO:0043204"(perikaryon)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051403"(stress-activated MAPK cascade)|go:"GO:0060561"(apoptotic process involved in morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0097060"(synaptic membrane)|go:"GO:0097512"(cardiac myofibril)|go:"GO:1905907"(negative regulation of amyloid fibril formation)|go:"GO:2000378"(negative regulation of reactive oxygen species metabolic process)|interpro:IPR001436(Alpha crystallin/Heat shock protein)|interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR003090(Alpha-crystallin, N-terminal)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR037882|mint:P02511|rcsb pdb:2KLR|rcsb pdb:2N0K|rcsb pdb:2WJ7|rcsb pdb:2Y1Y|rcsb pdb:2Y1Z|rcsb pdb:2YGD|rcsb pdb:3J07|rcsb pdb:2Y22|rcsb pdb:3L1G|rcsb pdb:3SGM|rcsb pdb:3SGN|rcsb pdb:3SGO|rcsb pdb:3SGP|rcsb pdb:3SGR|rcsb pdb:3SGS|rcsb pdb:4M5S|rcsb pdb:4M5T|rcsb pdb:5VVV|rcsb pdb:6BP9|reactome:R-HSA-3371571|refseq:NP_001876.1|refseq:XP_011540910.1|refseq:NP_001276736.1|refseq:NP_001276737.1|dip:DIP-35017N ensembl:ENSG00000109846(gene)|ensembl:ENST00000227251(transcript)|ensembl:ENST00000526180(transcript)|ensembl:ENST00000527899(transcript)|ensembl:ENST00000527950(transcript)|ensembl:ENST00000531198(transcript)|ensembl:ENST00000533475(transcript)|ensembl:ENST00000533879(transcript)|ensembl:ENST00000616970(transcript)|ensembl:ENST00000650687(transcript)|ensembl:ENST00000651164(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001666"(response to hypoxia)|go:"GO:0002088"(lens development in camera-type eye)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0006936"(muscle contraction)|go:"GO:0007021"(tubulin complex assembly)|go:"GO:0007517"(muscle organ development)|go:"GO:0008017"(microtubule binding)|go:"GO:0009986"(cell surface)|go:"GO:0010259"(multicellular organism aging)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010941"(regulation of cell death)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030018"(Z disc)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030424"(axon)|go:"GO:0031109"(microtubule polymerization or depolymerization)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031430"(M band)|go:"GO:0032355"(response to estradiol)|go:"GO:0032387"(negative regulation of intracellular transport)|go:"GO:0032432"(actin filament bundle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043197"(dendritic spine)|go:"GO:0043204"(perikaryon)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051403"(stress-activated MAPK cascade)|go:"GO:0060561"(apoptotic process involved in morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0097060"(synaptic membrane)|go:"GO:0097512"(cardiac myofibril)|go:"GO:1905907"(negative regulation of amyloid fibril formation)|go:"GO:2000378"(negative regulation of reactive oxygen species metabolic process)|interpro:IPR001436(Alpha crystallin/Heat shock protein)|interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR003090(Alpha-crystallin, N-terminal)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR037882|mint:P02511|rcsb pdb:2KLR|rcsb pdb:2N0K|rcsb pdb:2WJ7|rcsb pdb:2Y1Y|rcsb pdb:2Y1Z|rcsb pdb:2YGD|rcsb pdb:3J07|rcsb pdb:2Y22|rcsb pdb:3L1G|rcsb pdb:3SGM|rcsb pdb:3SGN|rcsb pdb:3SGO|rcsb pdb:3SGP|rcsb pdb:3SGR|rcsb pdb:3SGS|rcsb pdb:4M5S|rcsb pdb:4M5T|rcsb pdb:5VVV|rcsb pdb:6BP9|reactome:R-HSA-3371571|refseq:NP_001876.1|refseq:XP_011540910.1|refseq:NP_001276736.1|refseq:NP_001276737.1|dip:DIP-35017N psi-mi:"MI:0465"(dip) crc64:AE08BED46B7849CB crc64:AE08BED46B7849CB dip-version:1|dip-updated-by:nodeMerge04|dip-date-update:2011-10-22|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/05 2017/08/10 rogid:495Z42oQhkAUdADrAEOKIC5oICo9606 rogid:495Z42oQhkAUdADrAEOKIC5oICo9606 rigid:7aBGHTYzQMx7+hRsyz22EBt6WCQ false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q8WXD2-1 uniprotkb:O00429-1 intact:EBI-15690850|ensembl:ENSP00000220478 intact:EBI-15690834|ensembl:ENSP00000450399 psi-mi:q8wxd2-1(display_long)|uniprotkb:SCG3(gene name)|psi-mi:SCG3(display_short)|uniprotkb:Secretogranin III(gene name synonym)|uniprotkb:UNQ2502/PRO5990(orf name) psi-mi:o00429-1(display_long)|uniprotkb:DNM1L(gene name)|psi-mi:DNM1L(display_short)|uniprotkb:DLP1(gene name synonym)|uniprotkb:DRP1(gene name synonym)|uniprotkb:Dnm1p/Vps1p-like protein(gene name synonym)|uniprotkb:Dynamin family member proline-rich carboxyl-terminal domain less(gene name synonym)|uniprotkb:Dynamin-like protein(gene name synonym)|uniprotkb:Dynamin-like protein 4(gene name synonym)|uniprotkb:Dynamin-like protein IV(gene name synonym)|uniprotkb:Dynamin-related protein 1(gene name synonym)|uniprotkb:DLP1F(isoform synonym)|uniprotkb:HdynIV-WT(isoform synonym) psi-mi:"MI:0018"(two hybrid) DeGrado-Warren et al. (2008) pubmed:18330356|imex:IM-8752 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15690857|dip:DIP-201371E|imex:IM-8752-94 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000104112(gene)|ensembl:ENST00000220478(transcript)|intact:EBI-12162999(isoform-parent) ensembl:ENSG00000087470(gene)|ensembl:ENST00000549701(transcript)|intact:EBI-724571(isoform-parent) psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/05 2017/08/10 rogid:4FmR4obGCv49kROnQYYVJLDoubE9606 rogid:hmh7m80FPMdx6/3eUY6l0IK/AqY9606 rigid:HJwVdUvYOyeEetU1guZqsdISrls false - sufficient binding region:500-697|sufficient binding region:600-736|sufficient binding region:625-736 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P04792 uniprotkb:P02511 intact:EBI-352682|uniprotkb:Q6FI47|uniprotkb:Q96C20|uniprotkb:Q96EI7|uniprotkb:Q9UC34|uniprotkb:Q9UC35|uniprotkb:Q9UC36|uniprotkb:Q9UC31|ensembl:ENSP00000248553|uniprotkb:B2R4N8 intact:EBI-739060|uniprotkb:O43416|uniprotkb:B0YIX0|uniprotkb:Q9UC37|uniprotkb:Q9UC38|uniprotkb:Q9UC39|uniprotkb:Q9UC40|uniprotkb:Q9UC41|ensembl:ENSP00000227251|ensembl:ENSP00000433560|ensembl:ENSP00000434247|ensembl:ENSP00000435931|ensembl:ENSP00000436051|ensembl:ENSP00000436089|ensembl:ENSP00000437149|ensembl:ENSP00000483554|ensembl:ENSP00000498735|ensembl:ENSP00000499082 psi-mi:hspb1_human(display_long)|uniprotkb:HSPB1(gene name)|psi-mi:HSPB1(display_short)|uniprotkb:HSP27(gene name synonym)|uniprotkb:HSP28(gene name synonym)|uniprotkb:Heat shock 27 kDa protein(gene name synonym)|uniprotkb:Stress-responsive protein 27(gene name synonym)|uniprotkb:Estrogen-regulated 24 kDa protein(gene name synonym)|uniprotkb:28 kDa heat shock protein(gene name synonym) psi-mi:cryab_human(display_long)|uniprotkb:CRYAB(gene name)|psi-mi:CRYAB(display_short)|uniprotkb:CRYA2(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-27(gene name synonym)|uniprotkb:"Alpha(B)-crystallin"(gene name synonym)|uniprotkb:Rosenthal fiber component(gene name synonym)|uniprotkb:Heat shock protein beta-5(gene name synonym)|uniprotkb:HSPB5(gene name synonym) psi-mi:"MI:0018"(two hybrid) DeGrado-Warren et al. (2008) pubmed:18330356|imex:IM-8752 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15690815|dip:DIP-70013E|imex:IM-8752-56 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001531.1|ensembl:ENSG00000106211(gene)|ensembl:ENST00000248553(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0001895"(retina homeostasis)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0003723"(RNA binding)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008426"(protein kinase C inhibitor activity)|go:"GO:0009615"(response to virus)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030018"(Z disc)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035924"(cellular response to vascular endothelial growth factor stimulus)|go:"GO:0038033"(positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070527"(platelet aggregation)|go:"GO:0099641"(anterograde axonal protein transport)|go:"GO:1902176"(negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1904115"(axon cytoplasm)|go:"GO:2001028"(positive regulation of endothelial cell chemotaxis)|interpro:IPR001436(Alpha crystallin/Heat shock protein)|interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR037876|mint:P04792|rcsb pdb:2N3J|rcsb pdb:3Q9P|rcsb pdb:3Q9Q|rcsb pdb:4MJH|rcsb pdb:6DV5|rcsb pdb:6GJH|reactome:R-HSA-4420097|reactome:R-HSA-450408|reactome:R-HSA-5687128|reactome:R-HSA-9009391|dip:DIP-412N ensembl:ENSG00000109846(gene)|ensembl:ENST00000227251(transcript)|ensembl:ENST00000526180(transcript)|ensembl:ENST00000527899(transcript)|ensembl:ENST00000527950(transcript)|ensembl:ENST00000531198(transcript)|ensembl:ENST00000533475(transcript)|ensembl:ENST00000533879(transcript)|ensembl:ENST00000616970(transcript)|ensembl:ENST00000650687(transcript)|ensembl:ENST00000651164(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001666"(response to hypoxia)|go:"GO:0002088"(lens development in camera-type eye)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0006936"(muscle contraction)|go:"GO:0007021"(tubulin complex assembly)|go:"GO:0007517"(muscle organ development)|go:"GO:0008017"(microtubule binding)|go:"GO:0009986"(cell surface)|go:"GO:0010259"(multicellular organism aging)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010941"(regulation of cell death)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030018"(Z disc)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030424"(axon)|go:"GO:0031109"(microtubule polymerization or depolymerization)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031430"(M band)|go:"GO:0032355"(response to estradiol)|go:"GO:0032387"(negative regulation of intracellular transport)|go:"GO:0032432"(actin filament bundle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043197"(dendritic spine)|go:"GO:0043204"(perikaryon)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051403"(stress-activated MAPK cascade)|go:"GO:0060561"(apoptotic process involved in morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0097060"(synaptic membrane)|go:"GO:0097512"(cardiac myofibril)|go:"GO:1905907"(negative regulation of amyloid fibril formation)|go:"GO:2000378"(negative regulation of reactive oxygen species metabolic process)|interpro:IPR001436(Alpha crystallin/Heat shock protein)|interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR003090(Alpha-crystallin, N-terminal)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR037882|mint:P02511|rcsb pdb:2KLR|rcsb pdb:2N0K|rcsb pdb:2WJ7|rcsb pdb:2Y1Y|rcsb pdb:2Y1Z|rcsb pdb:2YGD|rcsb pdb:3J07|rcsb pdb:2Y22|rcsb pdb:3L1G|rcsb pdb:3SGM|rcsb pdb:3SGN|rcsb pdb:3SGO|rcsb pdb:3SGP|rcsb pdb:3SGR|rcsb pdb:3SGS|rcsb pdb:4M5S|rcsb pdb:4M5T|rcsb pdb:5VVV|rcsb pdb:6BP9|reactome:R-HSA-3371571|refseq:NP_001876.1|refseq:XP_011540910.1|refseq:NP_001276736.1|refseq:NP_001276737.1|dip:DIP-35017N psi-mi:"MI:0465"(dip) crc64:1B4DC44A6F6606D5 crc64:AE08BED46B7849CB dip-version:1|dip-updated-by:nodeMerge04|dip-date-update:2011-10-22|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/05 2017/08/10 rogid:vrDXIdzP30aHSDLHOh2D4x54eJY9606 rogid:495Z42oQhkAUdADrAEOKIC5oICo9606 rigid:HlIost5vRGNZhOzHD7XSsVsRheE false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q04206 uniprotkb:P47712 intact:EBI-73886|ensembl:ENSP00000384273|uniprotkb:Q6GTV1|uniprotkb:Q6SLK1 intact:EBI-1044090|uniprotkb:Q29R80|ensembl:ENSP00000356436|uniprotkb:B1AKG4 psi-mi:tf65_human(display_long)|uniprotkb:Nuclear factor NF-kappa-B p65 subunit(gene name synonym)|uniprotkb:RELA(gene name)|psi-mi:RELA(display_short)|uniprotkb:NFKB3(gene name synonym)|uniprotkb:Nuclear factor of kappa light polypeptide gene enhancer in B-cells 3(gene name synonym) psi-mi:pa24a_human(display_long)|uniprotkb:PLA2G4A(gene name)|psi-mi:PLA2G4A(display_short)|uniprotkb:CPLA2(gene name synonym)|uniprotkb:PLA2G4(gene name synonym)|uniprotkb:Phospholipase A2 group IVA(gene name synonym) psi-mi:"MI:0018"(two hybrid) DeGrado-Warren et al. (2008) pubmed:18330356|imex:IM-8752 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15690879|dip:DIP-201380E|imex:IM-8752-128 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000173039(gene)|ensembl:ENST00000406246(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|refseq:NP_001138610.1|refseq:NP_068810.3|refseq:NP_001230913.1|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0070301"(cellular response to hydrogen peroxide)|dip:DIP-24238N|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001889"(liver development)|go:"GO:0001942"(hair follicle development)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006117"(acetaldehyde metabolic process)|go:"GO:0006325"(chromatin organization)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006954"(inflammatory response)|go:"GO:0006968"(cellular defense response)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0007568"(aging)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0010033"(response to organic substance)|go:"GO:0010224"(response to UV-B)|go:"GO:0014040"(positive regulation of Schwann cell differentiation)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032495"(response to muramyl dipeptide)|go:"GO:0032570"(response to progesterone)|go:"GO:0032735"(positive regulation of interleukin-12 production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032868"(response to insulin)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0033234"(negative regulation of protein sumoylation)|go:"GO:0033590"(response to cobalamin)|go:"GO:0034097"(response to cytokine)|go:"GO:0035525"(NF-kappaB p50/p65 complex)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0035924"(cellular response to vascular endothelial growth factor stimulus)|go:"GO:0035994"(response to muscle stretch)|go:"GO:0038061"(NIK/NF-kappaB signaling)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0042277"(peptide binding)|go:"GO:0042301"(phosphate ion binding)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042805"(actinin binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043200"(response to amino acid)|go:"GO:0043278"(response to morphine)|go:"GO:0043620"(regulation of DNA-templated transcription in response to stress)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0050862"(positive regulation of T cell receptor signaling pathway)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051591"(response to cAMP)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0051607"(defense response to virus)|go:"GO:0070431"(nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:"GO:0070498"(interleukin-1-mediated signaling pathway)|go:"GO:0070555"(response to interleukin-1)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071223"(cellular response to lipoteichoic acid)|go:"GO:0071224"(cellular response to peptidoglycan)|go:"GO:0071316"(cellular response to nicotine)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0071354"(cellular response to interleukin-6)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071532"(ankyrin repeat binding)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099527"(postsynapse to nucleus signaling pathway)|go:"GO:0140296"(general transcription initiation factor binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1901222"(regulation of NIK/NF-kappaB signaling)|go:"GO:1901223"(negative regulation of NIK/NF-kappaB signaling)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1901522"(positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus)|go:"GO:1902004"(positive regulation of amyloid-beta formation)|go:"GO:1902894"(negative regulation of miRNA transcription)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1904385"(cellular response to angiotensin)|go:"GO:1904996"(positive regulation of leukocyte adhesion to vascular endothelial cell)|go:"GO:2000630"(positive regulation of miRNA metabolic process)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR000451(NF-kappa-B/Rel/dorsal)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011539(Rel homology)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR030492|interpro:IPR030495|interpro:IPR032397|interpro:IPR033926|interpro:IPR037059|mint:Q04206|rcsb pdb:1NFI|rcsb pdb:2LSP|rcsb pdb:2O61|rcsb pdb:3GUT|rcsb pdb:3QXY|rcsb pdb:3RC0|rcsb pdb:4KV1|rcsb pdb:4KV4|rcsb pdb:5U4K|rcsb pdb:5URN|rcsb pdb:6NV2|rcsb pdb:6QHL|rcsb pdb:6QHM|rcsb pdb:6YOW|rcsb pdb:6YOX|rcsb pdb:6YOY|rcsb pdb:6YP2|rcsb pdb:6YP3|rcsb pdb:6YP8|rcsb pdb:6YPL|rcsb pdb:6YPY|rcsb pdb:6YQ2|rcsb pdb:7BI3|rcsb pdb:7BIQ|rcsb pdb:7BIY|rcsb pdb:7BJF|rcsb pdb:7BJL|rcsb pdb:7BJW|rcsb pdb:7BKH|rcsb pdb:7NJ9|rcsb pdb:7NJB|rcsb pdb:7NK3|rcsb pdb:7NK5|rcsb pdb:7NLA|rcsb pdb:7NLE|rcsb pdb:7NM1|rcsb pdb:7NM3|rcsb pdb:7NM9|rcsb pdb:7NQP|rcsb pdb:7NR7|rcsb pdb:7NSV|rcsb pdb:7NV4|rcsb pdb:7NVI|rcsb pdb:7NWS|rcsb pdb:7NXS|rcsb pdb:7NXT|rcsb pdb:7NXW|rcsb pdb:7NXY|rcsb pdb:7NY4|rcsb pdb:7NYE|rcsb pdb:7NYF|rcsb pdb:7NYG|rcsb pdb:7NZ6|rcsb pdb:7NZG|rcsb pdb:7NZK|rcsb pdb:7NZV|rcsb pdb:7O34|rcsb pdb:7O3A|rcsb pdb:7O3F|rcsb pdb:7O3P|rcsb pdb:7O3Q|rcsb pdb:7O3R|rcsb pdb:7O3S|rcsb pdb:7O57|rcsb pdb:7O59|rcsb pdb:7O5A|rcsb pdb:7O5C|rcsb pdb:7O5D|rcsb pdb:7O5F|rcsb pdb:7O5G|rcsb pdb:7O5O|rcsb pdb:7O5P|rcsb pdb:7O5S|rcsb pdb:7O5U|rcsb pdb:7O5X|rcsb pdb:7O6F|rcsb pdb:7O6G|rcsb pdb:7O6I|rcsb pdb:7O6J|rcsb pdb:7O6K|rcsb pdb:7O6M|rcsb pdb:7O6O|reactome:R-HSA-1169091|reactome:R-HSA-1810476|reactome:R-HSA-193692|reactome:R-HSA-202424|reactome:R-HSA-209560|reactome:R-HSA-2559582|reactome:R-HSA-2871837|reactome:R-HSA-3134963|reactome:R-HSA-3214841|reactome:R-HSA-381340|reactome:R-HSA-445989|reactome:R-HSA-448706|reactome:R-HSA-4755510|reactome:R-HSA-5603029|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5621575|reactome:R-HSA-5660668|reactome:R-HSA-844456|reactome:R-HSA-8853884|reactome:R-HSA-9020702|reactome:R-HSA-933542|reactome:R-HSA-9660826 refseq:NP_077734.1|go:"GO:0102567"|go:"GO:0102568"|go:"GO:1902387"(ceramide 1-phosphate binding)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR002642(Lysophospholipase, catalytic region)|interpro:IPR016035(Acyl transferase/acyl hydrolase/lysophospholipase)|interpro:IPR035892|interpro:IPR041847|rcsb pdb:1BCI|rcsb pdb:1CJY|rcsb pdb:1RLW|reactome:R-HSA-111995|reactome:R-HSA-1482788|reactome:R-HSA-1482798|reactome:R-HSA-1482801|reactome:R-HSA-1482839|reactome:R-HSA-1482922|reactome:R-HSA-1482925|reactome:R-HSA-1483115|reactome:R-HSA-1483166|reactome:R-HSA-2142753|reactome:R-HSA-418592|reactome:R-HSA-432142|reactome:R-HSA-6811436|ensembl:ENSG00000116711(gene)|ensembl:ENST00000367466(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001516"(prostaglandin biosynthetic process)|go:"GO:0002827"(positive regulation of T-helper 1 type immune response)|go:"GO:0004622"(lysophospholipase activity)|go:"GO:0004623"(phospholipase A2 activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006071"(glycerol metabolic process)|go:"GO:0006640"(monoacylglycerol biosynthetic process)|go:"GO:0006663"(platelet activating factor biosynthetic process)|go:"GO:0008374"(O-acyltransferase activity)|go:"GO:0010314"(phosphatidylinositol-5-phosphate binding)|go:"GO:0010572"(positive regulation of platelet activation)|go:"GO:0019369"(arachidonic acid metabolic process)|go:"GO:0019370"(leukotriene biosynthetic process)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0032308"(positive regulation of prostaglandin secretion)|go:"GO:0034478"(phosphatidylglycerol catabolic process)|go:"GO:0034638"(phosphatidylcholine catabolic process)|go:"GO:0036151"(phosphatidylcholine acyl-chain remodeling)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043032"(positive regulation of macrophage activation)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046475"(glycerophospholipid catabolic process)|go:"GO:0047498"(calcium-dependent phospholipase A2 activity)|go:"GO:0047499"(calcium-independent phospholipase A2 activity)|go:"GO:0050482"(arachidonic acid secretion)|go:"GO:0070273"(phosphatidylinositol-4-phosphate binding)|go:"GO:0071236"(cellular response to antibiotic)|go:"GO:0102545"(phosphatidyl phospholipase B activity)|go:"GO:0006690"(icosanoid metabolic process)|refseq:NP_001298122.1|refseq:XP_011507944.1|dip:DIP-40991N psi-mi:"MI:0465"(dip) - crc64:EE71CA0EBE617856 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/05 2017/08/10 rogid:w/ClZ7PzdLH1LLxTGrk22KUz8V49606 rogid:D/yM7EFWP6xaMQ//7wutJS5D3jw9606 rigid:nJ9wyjPmceTE1CprF0m56nxGcpc false - sufficient binding region:1-129 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q16520 uniprotkb:P35638-1 intact:EBI-749503|ensembl:ENSP00000286639 intact:EBI-15690897|ensembl:ENSP00000340671|ensembl:ENSP00000447188|ensembl:ENSP00000494844 psi-mi:batf_human(display_long)|uniprotkb:SF-HT-activated gene 2 protein(gene name synonym)|uniprotkb:BATF(gene name)|psi-mi:BATF(display_short)|uniprotkb:B-cell-activating transcription factor(gene name synonym) psi-mi:p35638-1(display_long)|uniprotkb:DDIT3(gene name)|psi-mi:DDIT3(display_short)|uniprotkb:CHOP(gene name synonym)|uniprotkb:CHOP10(gene name synonym)|uniprotkb:GADD153(gene name synonym)|uniprotkb:C/EBP zeta(gene name synonym)|uniprotkb:C/EBP-homologous protein(gene name synonym)|uniprotkb:C/EBP-homologous protein 10(gene name synonym)|uniprotkb:CCAAT/enhancer-binding protein homologous protein(gene name synonym)|uniprotkb:Growth arrest and DNA damage-inducible protein GADD153(gene name synonym) psi-mi:"MI:0018"(two hybrid) DeGrado-Warren et al. (2008) pubmed:18330356|imex:IM-8752 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15690910|dip:DIP-201396E|imex:IM-8752-130 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006390.1|dip:DIP-52482N|ensembl:ENSG00000156127(gene)|ensembl:ENST00000286639(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0002320"(lymphoid progenitor cell differentiation)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0030330"(DNA damage response, signal transduction by p53 class mediator)|go:"GO:0042832"(defense response to protozoan)|go:"GO:0043011"(myeloid dendritic cell differentiation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045064"(T-helper 2 cell differentiation)|go:"GO:0045190"(isotype switching)|go:"GO:0060218"(hematopoietic stem cell differentiation)|go:"GO:0072539"(T-helper 17 cell differentiation)|go:"GO:0072540"(T-helper 17 cell lineage commitment)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000837(Fos transforming protein)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029820|mint:Q16520|reactome:R-HSA-6785807 ensembl:ENSG00000175197(gene)|ensembl:ENST00000346473(transcript)|ensembl:ENST00000547303(transcript)|ensembl:ENST00000623876(transcript)|intact:EBI-742651(isoform-parent) psi-mi:"MI:0465"(dip) crc64:7FD633C6F1963DF4 - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/05 2017/08/10 rogid:rZdG+kauGaMPmB9bp0fV2W0t4lk9606 rogid:xyMsMwPwid+S2IYb3H0K0pnUc309606 rigid:O15HEKxIOAqh5ogx4lDB6tLGN9s false - sufficient binding region:75-167|sufficient binding region:90-165 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q15019-1 uniprotkb:Q99719-1 intact:EBI-5279816|ensembl:ENSP00000353157|ensembl:ENSP00000375832|ensembl:ENSP00000375834|ensembl:ENSP00000385172 intact:EBI-15690930|ensembl:ENSP00000391311 psi-mi:q15019-1(display_long)|uniprotkb:SEPTIN2(gene name)|psi-mi:SEPTIN2(display_short)|uniprotkb:DIFF6(gene name synonym)|uniprotkb:KIAA0158(gene name synonym)|uniprotkb:NEDD5(gene name synonym)|uniprotkb:Neural precursor cell expressed developmentally down-regulated protein 5(gene name synonym)|uniprotkb:SEPT2(gene name synonym) psi-mi:q99719-1(display_long)|uniprotkb:SEPTIN5(gene name)|psi-mi:SEPTIN5(display_short)|uniprotkb:Cell division control-related protein 1(gene name synonym)|uniprotkb:PNUTL1(gene name synonym)|uniprotkb:Peanut-like protein 1(gene name synonym)|uniprotkb:SEPT5(gene name synonym) psi-mi:"MI:0018"(two hybrid) DeGrado-Warren et al. (2008) pubmed:18330356|imex:IM-8752 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15690938|dip:DIP-201365E|imex:IM-8752-152 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000168385(gene)|ensembl:ENST00000360051(transcript)|ensembl:ENST00000391971(transcript)|ensembl:ENST00000391973(transcript)|ensembl:ENST00000402092(transcript)|intact:EBI-741220(isoform-parent) ensembl:ENSG00000184702(gene)|ensembl:ENST00000455784(transcript)|intact:EBI-373345(isoform-parent) psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/05 2017/08/10 rogid:H0Us8GtPe2XuXlOYXC0DX79kB/49606 rogid:kubhD1O+WmJeDWTlX+rcjpP9yRc9606 rigid:QnONYnZZYVrSjtnt59VxGN18DwI false - sufficient binding region:1-230|sufficient binding region:25-290 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P62195-1 uniprotkb:Q96EK4 intact:EBI-15690958|ensembl:ENSP00000310572 intact:EBI-1790529|uniprotkb:O94795|uniprotkb:A8K002|uniprotkb:A4UCT5|ensembl:ENSP00000304689 psi-mi:p62195-1(display_long)|uniprotkb:PSMC5(gene name)|psi-mi:PSMC5(display_short)|uniprotkb:SUG1(gene name synonym)|uniprotkb:26S proteasome AAA-ATPase subunit RPT6(gene name synonym)|uniprotkb:Proteasome 26S subunit ATPase 5(gene name synonym)|uniprotkb:Proteasome subunit p45(gene name synonym)|uniprotkb:Thyroid hormone receptor-interacting protein 1(gene name synonym)|uniprotkb:p45/SUG(gene name synonym) psi-mi:tha11_human(display_long)|uniprotkb:THAP11(gene name)|psi-mi:THAP11(display_short)|uniprotkb:HRIHFB2206(orf name) psi-mi:"MI:0018"(two hybrid) DeGrado-Warren et al. (2008) pubmed:18330356|imex:IM-8752 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15690969|dip:DIP-201388E|imex:IM-8752-186 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000087191(gene)|ensembl:ENST00000310144(transcript)|intact:EBI-357745(isoform-parent)|uniprotkb:P62195-1(isoform-parent) refseq:NP_065190.2|dip:DIP-46732N|ensembl:ENSP00000304689|ensembl:ENSG00000168286(gene)|ensembl:ENST00000303596(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|interpro:IPR006612(Zinc finger, C2CH-type)|rcsb pdb:2LAU|rcsb pdb:5AJS psi-mi:"MI:0465"(dip) - crc64:25235D20CB54D8C2 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/05 2017/08/10 rogid:zgUTOX/O4m86U/Nf+pnT7u0m0gY9606 rogid:qzl6RN2xlTuDBruwyKLyDTNRCKE9606 rigid:Nhlfncs0FVN2jgMAyB4S6FVe/jw false - sufficient binding region:100-301|sufficient binding region:196-314|sufficient binding region:230-314 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q04323-2 uniprotkb:P47712 intact:EBI-11530712|ensembl:ENSP00000294119 intact:EBI-1044090|uniprotkb:Q29R80|ensembl:ENSP00000356436|uniprotkb:B1AKG4 psi-mi:q04323-2(display_long)|uniprotkb:UBXN1(gene name)|psi-mi:UBXN1(display_short)|uniprotkb:SAKS1(gene name synonym)|uniprotkb:SAPK substrate protein 1(gene name synonym)|uniprotkb:UBA/UBX 33.3 kDa protein(gene name synonym) psi-mi:pa24a_human(display_long)|uniprotkb:PLA2G4A(gene name)|psi-mi:PLA2G4A(display_short)|uniprotkb:CPLA2(gene name synonym)|uniprotkb:PLA2G4(gene name synonym)|uniprotkb:Phospholipase A2 group IVA(gene name synonym) psi-mi:"MI:0018"(two hybrid) DeGrado-Warren et al. (2008) pubmed:18330356|imex:IM-8752 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15690991|dip:DIP-201379E|imex:IM-8752-132 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000162191(gene)|ensembl:ENST00000294119(transcript)|intact:EBI-1058647(isoform-parent)|uniprotkb:Q04323-2(isoform-parent) refseq:NP_077734.1|go:"GO:0102567"|go:"GO:0102568"|go:"GO:1902387"(ceramide 1-phosphate binding)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR002642(Lysophospholipase, catalytic region)|interpro:IPR016035(Acyl transferase/acyl hydrolase/lysophospholipase)|interpro:IPR035892|interpro:IPR041847|rcsb pdb:1BCI|rcsb pdb:1CJY|rcsb pdb:1RLW|reactome:R-HSA-111995|reactome:R-HSA-1482788|reactome:R-HSA-1482798|reactome:R-HSA-1482801|reactome:R-HSA-1482839|reactome:R-HSA-1482922|reactome:R-HSA-1482925|reactome:R-HSA-1483115|reactome:R-HSA-1483166|reactome:R-HSA-2142753|reactome:R-HSA-418592|reactome:R-HSA-432142|reactome:R-HSA-6811436|ensembl:ENSG00000116711(gene)|ensembl:ENST00000367466(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001516"(prostaglandin biosynthetic process)|go:"GO:0002827"(positive regulation of T-helper 1 type immune response)|go:"GO:0004622"(lysophospholipase activity)|go:"GO:0004623"(phospholipase A2 activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006071"(glycerol metabolic process)|go:"GO:0006640"(monoacylglycerol biosynthetic process)|go:"GO:0006663"(platelet activating factor biosynthetic process)|go:"GO:0008374"(O-acyltransferase activity)|go:"GO:0010314"(phosphatidylinositol-5-phosphate binding)|go:"GO:0010572"(positive regulation of platelet activation)|go:"GO:0019369"(arachidonic acid metabolic process)|go:"GO:0019370"(leukotriene biosynthetic process)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0032308"(positive regulation of prostaglandin secretion)|go:"GO:0034478"(phosphatidylglycerol catabolic process)|go:"GO:0034638"(phosphatidylcholine catabolic process)|go:"GO:0036151"(phosphatidylcholine acyl-chain remodeling)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043032"(positive regulation of macrophage activation)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046475"(glycerophospholipid catabolic process)|go:"GO:0047498"(calcium-dependent phospholipase A2 activity)|go:"GO:0047499"(calcium-independent phospholipase A2 activity)|go:"GO:0050482"(arachidonic acid secretion)|go:"GO:0070273"(phosphatidylinositol-4-phosphate binding)|go:"GO:0071236"(cellular response to antibiotic)|go:"GO:0102545"(phosphatidyl phospholipase B activity)|go:"GO:0006690"(icosanoid metabolic process)|refseq:NP_001298122.1|refseq:XP_011507944.1|dip:DIP-40991N psi-mi:"MI:0465"(dip) isoform-comment:No experimental confirmation available. crc64:EE71CA0EBE617856 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/05 2017/08/10 rogid:3DD93eyg5bSqmm3twiOfff+2Bps9606 rogid:D/yM7EFWP6xaMQ//7wutJS5D3jw9606 rigid:SsYe5JHfccXNucFOMabGZ0E7NyY false - sufficient binding region:1-121|sufficient binding region:1-129 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9BWW4 uniprotkb:O43679-1 intact:EBI-2902395|uniprotkb:A8K0A9|uniprotkb:Q5T860|uniprotkb:Q5T861|uniprotkb:Q9BTM0|uniprotkb:Q9BWW3|ensembl:ENSP00000479674 intact:EBI-15691011|ensembl:ENSP00000306772 psi-mi:ssbp3_human(display_long)|uniprotkb:SSBP3(gene name)|psi-mi:SSBP3(display_short)|uniprotkb:SSDP(gene name synonym)|uniprotkb:SSDP1(gene name synonym)|uniprotkb:Sequence-specific single-stranded-DNA-binding protein(gene name synonym) psi-mi:o43679-1(display_long)|uniprotkb:LDB2(gene name)|psi-mi:LDB2(display_short)|uniprotkb:CLIM1(gene name synonym)|uniprotkb:Carboxyl-terminal LIM domain-binding protein 1(gene name synonym)|uniprotkb:LIM domain-binding factor CLIM1(gene name synonym)|uniprotkb:CLIM1a(isoform synonym)|uniprotkb:a(isoform synonym) psi-mi:"MI:0018"(two hybrid) DeGrado-Warren et al. (2008) pubmed:18330356|imex:IM-8752 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15691021|dip:DIP-201387E|imex:IM-8752-58 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001009955.1|refseq:NP_060540.2|refseq:NP_663768.1|dip:DIP-48897N|ensembl:ENSG00000157216(gene)|ensembl:ENST00000610401(transcript)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR006594(LisH dimerisation motif)|interpro:IPR008116(Sequence-specific single-strand DNA-binding protein)|mint:Q9BWW4 intact:EBI-2865580(isoform-parent)|ensembl:ENSG00000169744(gene)|ensembl:ENST00000304523(transcript) psi-mi:"MI:0465"(dip) crc64:DBBB169D4EE10536 - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/05 2017/08/10 rogid:GD7FO6kR/5WawTNP0MaDcmIf7f49606 rogid:3p/spcR1ariBlpLJczJxP5Mfi9w9606 rigid:L6bX54KnnkVH6crqEK3LaMbatMk false - sufficient binding region:1-300 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P02511 uniprotkb:P02511 intact:EBI-739060|uniprotkb:O43416|uniprotkb:B0YIX0|uniprotkb:Q9UC37|uniprotkb:Q9UC38|uniprotkb:Q9UC39|uniprotkb:Q9UC40|uniprotkb:Q9UC41|ensembl:ENSP00000227251|ensembl:ENSP00000433560|ensembl:ENSP00000434247|ensembl:ENSP00000435931|ensembl:ENSP00000436051|ensembl:ENSP00000436089|ensembl:ENSP00000437149|ensembl:ENSP00000483554|ensembl:ENSP00000498735|ensembl:ENSP00000499082 intact:EBI-739060|uniprotkb:O43416|uniprotkb:B0YIX0|uniprotkb:Q9UC37|uniprotkb:Q9UC38|uniprotkb:Q9UC39|uniprotkb:Q9UC40|uniprotkb:Q9UC41|ensembl:ENSP00000227251|ensembl:ENSP00000433560|ensembl:ENSP00000434247|ensembl:ENSP00000435931|ensembl:ENSP00000436051|ensembl:ENSP00000436089|ensembl:ENSP00000437149|ensembl:ENSP00000483554|ensembl:ENSP00000498735|ensembl:ENSP00000499082 psi-mi:cryab_human(display_long)|uniprotkb:CRYAB(gene name)|psi-mi:CRYAB(display_short)|uniprotkb:CRYA2(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-27(gene name synonym)|uniprotkb:"Alpha(B)-crystallin"(gene name synonym)|uniprotkb:Rosenthal fiber component(gene name synonym)|uniprotkb:Heat shock protein beta-5(gene name synonym)|uniprotkb:HSPB5(gene name synonym) psi-mi:cryab_human(display_long)|uniprotkb:CRYAB(gene name)|psi-mi:CRYAB(display_short)|uniprotkb:CRYA2(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-27(gene name synonym)|uniprotkb:"Alpha(B)-crystallin"(gene name synonym)|uniprotkb:Rosenthal fiber component(gene name synonym)|uniprotkb:Heat shock protein beta-5(gene name synonym)|uniprotkb:HSPB5(gene name synonym) psi-mi:"MI:0018"(two hybrid) DeGrado-Warren et al. (2008) pubmed:18330356|imex:IM-8752 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15691079|dip:DIP-185604E|imex:IM-8752-74 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000109846(gene)|ensembl:ENST00000227251(transcript)|ensembl:ENST00000526180(transcript)|ensembl:ENST00000527899(transcript)|ensembl:ENST00000527950(transcript)|ensembl:ENST00000531198(transcript)|ensembl:ENST00000533475(transcript)|ensembl:ENST00000533879(transcript)|ensembl:ENST00000616970(transcript)|ensembl:ENST00000650687(transcript)|ensembl:ENST00000651164(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001666"(response to hypoxia)|go:"GO:0002088"(lens development in camera-type eye)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0006936"(muscle contraction)|go:"GO:0007021"(tubulin complex assembly)|go:"GO:0007517"(muscle organ development)|go:"GO:0008017"(microtubule binding)|go:"GO:0009986"(cell surface)|go:"GO:0010259"(multicellular organism aging)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010941"(regulation of cell death)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030018"(Z disc)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030424"(axon)|go:"GO:0031109"(microtubule polymerization or depolymerization)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031430"(M band)|go:"GO:0032355"(response to estradiol)|go:"GO:0032387"(negative regulation of intracellular transport)|go:"GO:0032432"(actin filament bundle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043197"(dendritic spine)|go:"GO:0043204"(perikaryon)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051403"(stress-activated MAPK cascade)|go:"GO:0060561"(apoptotic process involved in morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0097060"(synaptic membrane)|go:"GO:0097512"(cardiac myofibril)|go:"GO:1905907"(negative regulation of amyloid fibril formation)|go:"GO:2000378"(negative regulation of reactive oxygen species metabolic process)|interpro:IPR001436(Alpha crystallin/Heat shock protein)|interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR003090(Alpha-crystallin, N-terminal)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR037882|mint:P02511|rcsb pdb:2KLR|rcsb pdb:2N0K|rcsb pdb:2WJ7|rcsb pdb:2Y1Y|rcsb pdb:2Y1Z|rcsb pdb:2YGD|rcsb pdb:3J07|rcsb pdb:2Y22|rcsb pdb:3L1G|rcsb pdb:3SGM|rcsb pdb:3SGN|rcsb pdb:3SGO|rcsb pdb:3SGP|rcsb pdb:3SGR|rcsb pdb:3SGS|rcsb pdb:4M5S|rcsb pdb:4M5T|rcsb pdb:5VVV|rcsb pdb:6BP9|reactome:R-HSA-3371571|refseq:NP_001876.1|refseq:XP_011540910.1|refseq:NP_001276736.1|refseq:NP_001276737.1|dip:DIP-35017N ensembl:ENSG00000109846(gene)|ensembl:ENST00000227251(transcript)|ensembl:ENST00000526180(transcript)|ensembl:ENST00000527899(transcript)|ensembl:ENST00000527950(transcript)|ensembl:ENST00000531198(transcript)|ensembl:ENST00000533475(transcript)|ensembl:ENST00000533879(transcript)|ensembl:ENST00000616970(transcript)|ensembl:ENST00000650687(transcript)|ensembl:ENST00000651164(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001666"(response to hypoxia)|go:"GO:0002088"(lens development in camera-type eye)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0006936"(muscle contraction)|go:"GO:0007021"(tubulin complex assembly)|go:"GO:0007517"(muscle organ development)|go:"GO:0008017"(microtubule binding)|go:"GO:0009986"(cell surface)|go:"GO:0010259"(multicellular organism aging)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010941"(regulation of cell death)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030018"(Z disc)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030424"(axon)|go:"GO:0031109"(microtubule polymerization or depolymerization)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031430"(M band)|go:"GO:0032355"(response to estradiol)|go:"GO:0032387"(negative regulation of intracellular transport)|go:"GO:0032432"(actin filament bundle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043197"(dendritic spine)|go:"GO:0043204"(perikaryon)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051403"(stress-activated MAPK cascade)|go:"GO:0060561"(apoptotic process involved in morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0097060"(synaptic membrane)|go:"GO:0097512"(cardiac myofibril)|go:"GO:1905907"(negative regulation of amyloid fibril formation)|go:"GO:2000378"(negative regulation of reactive oxygen species metabolic process)|interpro:IPR001436(Alpha crystallin/Heat shock protein)|interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR003090(Alpha-crystallin, N-terminal)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR037882|mint:P02511|rcsb pdb:2KLR|rcsb pdb:2N0K|rcsb pdb:2WJ7|rcsb pdb:2Y1Y|rcsb pdb:2Y1Z|rcsb pdb:2YGD|rcsb pdb:3J07|rcsb pdb:2Y22|rcsb pdb:3L1G|rcsb pdb:3SGM|rcsb pdb:3SGN|rcsb pdb:3SGO|rcsb pdb:3SGP|rcsb pdb:3SGR|rcsb pdb:3SGS|rcsb pdb:4M5S|rcsb pdb:4M5T|rcsb pdb:5VVV|rcsb pdb:6BP9|reactome:R-HSA-3371571|refseq:NP_001876.1|refseq:XP_011540910.1|refseq:NP_001276736.1|refseq:NP_001276737.1|dip:DIP-35017N psi-mi:"MI:0465"(dip) crc64:AE08BED46B7849CB crc64:AE08BED46B7849CB full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/05 2017/08/10 rogid:495Z42oQhkAUdADrAEOKIC5oICo9606 rogid:495Z42oQhkAUdADrAEOKIC5oICo9606 rigid:7aBGHTYzQMx7+hRsyz22EBt6WCQ false - sufficient binding region:1-78|sufficient binding region:3-175 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q15642-2 uniprotkb:P42684-1 intact:EBI-6550597|ensembl:ENSP00000320493 intact:EBI-15691099|ensembl:ENSP00000427562 psi-mi:q15642-2(display_long)|uniprotkb:A(isoform synonym)|uniprotkb:W(isoform synonym)|uniprotkb:TRIP10(gene name)|psi-mi:TRIP10(display_short)|uniprotkb:CIP4(gene name synonym)|uniprotkb:STOT(gene name synonym)|uniprotkb:STP(gene name synonym)|uniprotkb:Protein Felic(gene name synonym)|uniprotkb:Salt tolerant protein(gene name synonym)|uniprotkb:Thyroid receptor-interacting protein 10(gene name synonym) psi-mi:p42684-1(display_long)|uniprotkb:Abelson tyrosine-protein kinase 2(gene name synonym)|uniprotkb:ABL2(gene name)|psi-mi:ABL2(display_short)|uniprotkb:ABLL(gene name synonym)|uniprotkb:ARG(gene name synonym)|uniprotkb:Abelson murine leukemia viral oncogene homolog 2(gene name synonym)|uniprotkb:Abelson-related gene protein(gene name synonym)|uniprotkb:Tyrosine-protein kinase ARG(gene name synonym)|uniprotkb:1BLCTL(isoform synonym)|uniprotkb:IB(isoform synonym) psi-mi:"MI:0018"(two hybrid) DeGrado-Warren et al. (2008) pubmed:18330356|imex:IM-8752 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15691113|dip:DIP-201372E|imex:IM-8752-134 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q15642-2(isoform-parent)|ensembl:ENSG00000125733(gene)|ensembl:ENST00000313285(transcript)|intact:EBI-739936(isoform-parent) intact:EBI-1102694(isoform-parent)|ensembl:ENSG00000143322(gene)|ensembl:ENST00000502732(transcript) psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/05 2017/08/10 rogid:FppLeIANQu5tcNbD11u+F0kSOBQ9606 rogid:ct5SG4m0wewDSllBklIOi48BV7Q9606 rigid:CDCvZj6exmqk5nXbtMKQNlXTukY false - sufficient binding region:900-1080|sufficient binding region:950-1100 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9NVA2-1 uniprotkb:Q99719-1 intact:EBI-15691133|ensembl:ENSP00000264893 intact:EBI-15690930|ensembl:ENSP00000391311 psi-mi:q9nva2-1(display_long)|uniprotkb:SEPTIN11(gene name)|psi-mi:SEPTIN11(display_short)|uniprotkb:SEPT11(gene name synonym) psi-mi:q99719-1(display_long)|uniprotkb:SEPTIN5(gene name)|psi-mi:SEPTIN5(display_short)|uniprotkb:Cell division control-related protein 1(gene name synonym)|uniprotkb:PNUTL1(gene name synonym)|uniprotkb:Peanut-like protein 1(gene name synonym)|uniprotkb:SEPT5(gene name synonym) psi-mi:"MI:0018"(two hybrid) DeGrado-Warren et al. (2008) pubmed:18330356|imex:IM-8752 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15691138|dip:DIP-64778E|imex:IM-8752-114 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000138758(gene)|ensembl:ENST00000264893(transcript)|intact:EBI-957999(isoform-parent) ensembl:ENSG00000184702(gene)|ensembl:ENST00000455784(transcript)|intact:EBI-373345(isoform-parent) psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/05 2017/08/10 rogid:2dJm0WBfPs71hp1nBoMeGF/DR2s9606 rogid:kubhD1O+WmJeDWTlX+rcjpP9yRc9606 rigid:CSTL1d2SB9Df4vuZbOrc1Pll8OU false - sufficient binding region:25-290|sufficient binding region:30-330 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q8TAP4-1 uniprotkb:O43679-1 intact:EBI-15691158|ensembl:ENSP00000312856|ensembl:ENSP00000346689|ensembl:ENSP00000412479|ensembl:ENSP00000413703|ensembl:ENSP00000439275|ensembl:ENSP00000444393|ensembl:ENSP00000445751|ensembl:ENSP00000446115|ensembl:ENSP00000440099 intact:EBI-15691011|ensembl:ENSP00000306772 psi-mi:q8tap4-1(display_long)|uniprotkb:LMO3(gene name)|psi-mi:LMO3(display_short)|uniprotkb:RBTN3(gene name synonym)|uniprotkb:RBTNL2(gene name synonym)|uniprotkb:RHOM3(gene name synonym)|uniprotkb:Neuronal-specific transcription factor DAT1(gene name synonym)|uniprotkb:Rhombotin-3(gene name synonym) psi-mi:o43679-1(display_long)|uniprotkb:LDB2(gene name)|psi-mi:LDB2(display_short)|uniprotkb:CLIM1(gene name synonym)|uniprotkb:Carboxyl-terminal LIM domain-binding protein 1(gene name synonym)|uniprotkb:LIM domain-binding factor CLIM1(gene name synonym)|uniprotkb:CLIM1a(isoform synonym)|uniprotkb:a(isoform synonym) psi-mi:"MI:0018"(two hybrid) DeGrado-Warren et al. (2008) pubmed:18330356|imex:IM-8752 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15691168|dip:DIP-201373E|imex:IM-8752-60 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000048540(gene)|ensembl:ENST00000320122(transcript)|ensembl:ENST00000354662(transcript)|ensembl:ENST00000441439(transcript)|ensembl:ENST00000447609(transcript)|ensembl:ENST00000534946(transcript)|ensembl:ENST00000535535(transcript)|ensembl:ENST00000537304(transcript)|ensembl:ENST00000540848(transcript)|ensembl:ENST00000541846(transcript)|intact:EBI-742259(isoform-parent) intact:EBI-2865580(isoform-parent)|ensembl:ENSG00000169744(gene)|ensembl:ENST00000304523(transcript) psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/05 2017/08/10 rogid:cZJuQ9JWbTbuABfiuU3iIRoMWhc9606 rogid:3p/spcR1ariBlpLJczJxP5Mfi9w9606 rigid:AlQejbNvt3mQ+ItvtVttm9MLrn0 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9BUW7 uniprotkb:Q96EK4 intact:EBI-752084|uniprotkb:Q9Y3F7|uniprotkb:Q5SYV8|ensembl:ENSP00000362085 intact:EBI-1790529|uniprotkb:O94795|uniprotkb:A8K002|uniprotkb:A4UCT5|ensembl:ENSP00000304689 psi-mi:bbln_human(display_long)|uniprotkb:BBLN(gene name)|psi-mi:BBLN(display_short)|uniprotkb:C9orf16(gene name synonym)|uniprotkb:UPF0184 protein C9orf16(gene name synonym)|uniprotkb:EST00098(orf name) psi-mi:tha11_human(display_long)|uniprotkb:THAP11(gene name)|psi-mi:THAP11(display_short)|uniprotkb:HRIHFB2206(orf name) psi-mi:"MI:0018"(two hybrid) DeGrado-Warren et al. (2008) pubmed:18330356|imex:IM-8752 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15691184|dip:DIP-201390E|imex:IM-8752-154 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_077017.1|dip:DIP-29481N|ensembl:ENSG00000171159(gene)|ensembl:ENST00000372994(transcript)|interpro:IPR005374(Protein of unknown function UPF0184) refseq:NP_065190.2|dip:DIP-46732N|ensembl:ENSP00000304689|ensembl:ENSG00000168286(gene)|ensembl:ENST00000303596(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|interpro:IPR006612(Zinc finger, C2CH-type)|rcsb pdb:2LAU|rcsb pdb:5AJS psi-mi:"MI:0465"(dip) crc64:EBE1D0AFAAD6DABB crc64:25235D20CB54D8C2 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/05 2017/08/10 rogid:O4VcHghk63gMrjyh5XKmkZovFZ49606 rogid:qzl6RN2xlTuDBruwyKLyDTNRCKE9606 rigid:XrOs7+WuIrvpYtSgVfNAZFmiWD0 false - sufficient binding region:100-301|sufficient binding region:196-314|sufficient binding region:230-314 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P12955-1 uniprotkb:Q93009 intact:EBI-15691206|ensembl:ENSP00000244137 intact:EBI-302474|uniprotkb:A6NMY8|intact:EBI-28988230|ensembl:ENSP00000343535|uniprotkb:B7Z815|uniprotkb:H0Y3G8 psi-mi:p12955-1(display_long)|uniprotkb:PEPD(gene name)|psi-mi:PEPD(display_short)|uniprotkb:PRD(gene name synonym)|uniprotkb:Imidodipeptidase(gene name synonym)|uniprotkb:Peptidase D(gene name synonym)|uniprotkb:Proline dipeptidase(gene name synonym) psi-mi:ubp7_human(display_long)|uniprotkb:USP7(gene name)|psi-mi:USP7(display_short)|uniprotkb:HAUSP(gene name synonym)|uniprotkb:Ubiquitin thioesterase 7(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease 7(gene name synonym)|uniprotkb:Deubiquitinating enzyme 7(gene name synonym)|uniprotkb:Herpesvirus-associated ubiquitin-specific protease(gene name synonym) psi-mi:"MI:0018"(two hybrid) DeGrado-Warren et al. (2008) pubmed:18330356|imex:IM-8752 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15691215|dip:DIP-201394E|imex:IM-8752-96 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000124299(gene)|ensembl:ENST00000244137(transcript)|intact:EBI-948765(isoform-parent) rcsb pdb:4PYZ|rcsb pdb:4WPH|rcsb pdb:4WPI|rcsb pdb:4YOC|rcsb pdb:4YSI|rcsb pdb:4Z96|rcsb pdb:4Z97|rcsb pdb:5C56|rcsb pdb:5C6D|rcsb pdb:5FWI|rcsb pdb:5GG4|rcsb pdb:5J7T|rcsb pdb:5JTJ|rcsb pdb:5JTV|rcsb pdb:5KYB|rcsb pdb:4M5X|rcsb pdb:5KYC|rcsb pdb:5KYD|rcsb pdb:5KYE|rcsb pdb:5KYF|interpro:IPR029346|interpro:IPR038765|mint:Q93009|rcsb pdb:1NB8|rcsb pdb:1NBF|rcsb pdb:1YY6|rcsb pdb:1YZE|rcsb pdb:2F1W|rcsb pdb:2F1X|rcsb pdb:2F1Y|rcsb pdb:2F1Z|rcsb pdb:2FOJ|rcsb pdb:2FOO|rcsb pdb:2FOP|rcsb pdb:2KVR|rcsb pdb:2XXN|rcsb pdb:2YLM|rcsb pdb:3MQR|rcsb pdb:3MQS|rcsb pdb:4JJQ|rcsb pdb:4KG9|rcsb pdb:4M5W|go:"GO:0006283"(transcription-coupled nucleotide-excision repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010216"(maintenance of DNA methylation)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035520"(monoubiquitinated protein deubiquitination)|go:"GO:0035616"(histone H2B conserved C-terminal lysine deubiquitination)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0048511"(rhythmic process)|go:"GO:0050821"(protein stabilization)|go:"GO:0051090"(regulation of DNA-binding transcription factor activity)|go:"GO:0070536"(protein K63-linked deubiquitination)|go:"GO:0101005"(deubiquitinase activity)|go:"GO:1901537"(positive regulation of DNA demethylation)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|go:"GO:1904353"(regulation of telomere capping)|go:"GO:1905279"(regulation of retrograde transport, endosome to Golgi)|go:"GO:1990380"(Lys48-specific deubiquitinase activity)|interpro:IPR001394(Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)|interpro:IPR002083(MATH)|interpro:IPR008974(TRAF-like)|interpro:IPR018200|interpro:IPR024729|interpro:IPR028889|ensembl:ENSG00000187555(gene)|ensembl:ENST00000344836(transcript)|go:"GO:0002039"(p53 binding)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0006111"(regulation of gluconeogenesis)|rcsb pdb:5N9R|rcsb pdb:5N9T|rcsb pdb:5NGE|rcsb pdb:5NGF|rcsb pdb:5UQV|rcsb pdb:5UQX|rcsb pdb:5VS6|rcsb pdb:5VSB|rcsb pdb:5VSK|rcsb pdb:5WHC|rcsb pdb:6F5H|rcsb pdb:6M1K|rcsb pdb:6P5L|rcsb pdb:6VN2|rcsb pdb:6VN3|rcsb pdb:6VN4|rcsb pdb:6VN5|rcsb pdb:6VN6|rcsb pdb:7CM2|reactome:R-HSA-5689880|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6804757|reactome:R-HSA-8866652|reactome:R-HSA-8948747|refseq:NP_001273386.1|refseq:NP_003461.2|refseq:NP_001308787.1|ensembl:ENSP00000343535|ensembl:ENST00000381886|ensembl:ENSP00000371310|dip:DIP-29053N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/05 2017/08/10 rogid:S33ZGUuOs+AAE83dREDwbnMKJws9606 rogid:V+PXXBRM2zwlGQaeFiyjaQ9yf+A9606 rigid:lVgniJqjBEU+V35tgkOsfx4Vhm0 false - sufficient binding region:670-920|sufficient binding region:699-910 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q16181-1 uniprotkb:Q99719-1 intact:EBI-15691235 intact:EBI-15690930|ensembl:ENSP00000391311 psi-mi:q16181-1(display_long)|uniprotkb:SEPTIN7(gene name)|psi-mi:SEPTIN7(display_short)|uniprotkb:CDC10(gene name synonym)|uniprotkb:CDC10 protein homolog(gene name synonym)|uniprotkb:SEPT7(gene name synonym) psi-mi:q99719-1(display_long)|uniprotkb:SEPTIN5(gene name)|psi-mi:SEPTIN5(display_short)|uniprotkb:Cell division control-related protein 1(gene name synonym)|uniprotkb:PNUTL1(gene name synonym)|uniprotkb:Peanut-like protein 1(gene name synonym)|uniprotkb:SEPT5(gene name synonym) psi-mi:"MI:0018"(two hybrid) DeGrado-Warren et al. (2008) pubmed:18330356|imex:IM-8752 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15691242|dip:DIP-201383E|imex:IM-8752-76 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2009373(isoform-parent) ensembl:ENSG00000184702(gene)|ensembl:ENST00000455784(transcript)|intact:EBI-373345(isoform-parent) psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/05 2017/08/10 rogid:CweIjGLXC7eubvKR7vkkihEkcHg9606 rogid:kubhD1O+WmJeDWTlX+rcjpP9yRc9606 rigid:FVWZpoxOPgaN4VYzHkBdDyYBAfI false - sufficient binding region:1-230|sufficient binding region:25-290 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q5U651 uniprotkb:O43679-1 intact:EBI-2797123|uniprotkb:Q6U676|ensembl:ENSP00000222145 intact:EBI-15691011|ensembl:ENSP00000306772 psi-mi:rain_human(display_long)|uniprotkb:RASIP1(gene name)|psi-mi:RASIP1(display_short) psi-mi:o43679-1(display_long)|uniprotkb:LDB2(gene name)|psi-mi:LDB2(display_short)|uniprotkb:CLIM1(gene name synonym)|uniprotkb:Carboxyl-terminal LIM domain-binding protein 1(gene name synonym)|uniprotkb:LIM domain-binding factor CLIM1(gene name synonym)|uniprotkb:CLIM1a(isoform synonym)|uniprotkb:a(isoform synonym) psi-mi:"MI:0018"(two hybrid) DeGrado-Warren et al. (2008) pubmed:18330356|imex:IM-8752 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15691262|dip:DIP-201381E|imex:IM-8752-168 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) dip:DIP-29457N|refseq:NP_060275.2|ensembl:ENSG00000105538(gene)|ensembl:ENST00000222145(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001570"(vasculogenesis)|go:"GO:0005795"(Golgi stack)|go:"GO:0005911"(cell-cell junction)|go:"GO:0007165"(signal transduction)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033625"(positive regulation of integrin activation)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0051020"(GTPase binding)|go:"GO:1905709"(negative regulation of membrane permeability)|go:"GO:2000299"(negative regulation of Rho-dependent protein serine/threonine kinase activity)|interpro:IPR002710(Dilute)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR029071|interpro:IPR037983|rcsb pdb:5KHO|rcsb pdb:5KHQ|interpro:IPR000159(Ras-association) intact:EBI-2865580(isoform-parent)|ensembl:ENSG00000169744(gene)|ensembl:ENST00000304523(transcript) psi-mi:"MI:0465"(dip) crc64:470021F91B59EC52 - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/05 2017/08/10 rogid:L0Vu21+1Ec4kZs0C89QTTABdvnA9606 rogid:3p/spcR1ariBlpLJczJxP5Mfi9w9606 rigid:U164Ce4FCAmEoasGE0REQ6KAx+0 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P18848 uniprotkb:P35638-1 intact:EBI-492498|uniprotkb:Q9UH31|ensembl:ENSP00000336790|ensembl:ENSP00000379912|ensembl:ENSP00000501783|ensembl:ENSP00000501863|ensembl:ENSP00000502400|ensembl:ENSP00000502610|ensembl:ENSP00000505360|ensembl:ENSP00000384587|intact:EBI-740263|uniprotkb:Q96AQ3 intact:EBI-15690897|ensembl:ENSP00000340671|ensembl:ENSP00000447188|ensembl:ENSP00000494844 psi-mi:atf4_human(display_long)|uniprotkb:Activating transcription factor 4(gene name synonym)|uniprotkb:CREB2(gene name synonym)|uniprotkb:ATF4(gene name)|psi-mi:ATF4(display_short)|uniprotkb:TXREB(gene name synonym)|uniprotkb:Cyclic AMP-responsive element-binding protein 2(gene name synonym)|uniprotkb:Tax-responsive enhancer element-binding protein 67(gene name synonym) psi-mi:p35638-1(display_long)|uniprotkb:DDIT3(gene name)|psi-mi:DDIT3(display_short)|uniprotkb:CHOP(gene name synonym)|uniprotkb:CHOP10(gene name synonym)|uniprotkb:GADD153(gene name synonym)|uniprotkb:C/EBP zeta(gene name synonym)|uniprotkb:C/EBP-homologous protein(gene name synonym)|uniprotkb:C/EBP-homologous protein 10(gene name synonym)|uniprotkb:CCAAT/enhancer-binding protein homologous protein(gene name synonym)|uniprotkb:Growth arrest and DNA damage-inducible protein GADD153(gene name synonym) psi-mi:"MI:0018"(two hybrid) DeGrado-Warren et al. (2008) pubmed:18330356|imex:IM-8752 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15691300|dip:DIP-201395E|imex:IM-8752-188 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001666.2|refseq:NP_877962.1|ensembl:ENSG00000128272(gene)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005886"(plasma membrane)|go:"GO:0006094"(gluconeogenesis)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0008140"(cAMP response element binding protein binding)|go:"GO:0010575"(positive regulation of vascular endothelial growth factor production)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016607"(nuclear speck)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030282"(bone mineralization)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0031667"(response to nutrient levels)|go:"GO:0032057"(negative regulation of translational initiation in response to stress)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032991"(protein-containing complex)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0070309"(lens fiber cell morphogenesis)|go:"GO:0070982"(L-asparagine metabolic process)|go:"GO:0120163"(negative regulation of cold-induced thermogenesis)|go:"GO:0140467"(integrated stress response signaling)|go:"GO:0140468"(HRI-mediated signaling)|go:"GO:1903204"(negative regulation of oxidative stress-induced neuron death)|go:"GO:1903351"(cellular response to dopamine)|go:"GO:1990037"(Lewy body core)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990589"(ATF4-CREB1 transcription factor complex)|go:"GO:1990590"(ATF1-ATF4 transcription factor complex)|go:"GO:1990617"(CHOP-ATF4 complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029811|mint:P18848|rcsb pdb:1CI6|reactome:R-HSA-380994|reactome:R-HSA-381042|reactome:R-HSA-381183|reactome:R-HSA-9633012|reactome:R-HSA-9648895|go:"GO:0043005"(neuron projection)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043522"(leucine zipper domain binding)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045667"(regulation of osteoblast differentiation)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0034399"(nuclear periphery)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0034644"(cellular response to UV)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035162"(embryonic hemopoiesis)|go:"GO:0036003"(positive regulation of transcription from RNA polymerase II promoter in response to stress)|go:"GO:0036091"(positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress)|go:"GO:0036499"(PERK-mediated unfolded protein response)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042789"(mRNA transcription by RNA polymerase II)|go:"GO:0042802"(identical protein binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045943"(positive regulation of transcription by RNA polymerase I)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0061395"(positive regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|ensembl:ENST00000337304(transcript)|ensembl:ENST00000396680(transcript)|ensembl:ENST00000404241(transcript)|ensembl:ENST00000674568(transcript)|ensembl:ENST00000674835(transcript)|ensembl:ENST00000674920(transcript)|ensembl:ENST00000676346(transcript)|ensembl:ENST00000679776(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|refseq:XP_016884296.1|dip:DIP-354N ensembl:ENSG00000175197(gene)|ensembl:ENST00000346473(transcript)|ensembl:ENST00000547303(transcript)|ensembl:ENST00000623876(transcript)|intact:EBI-742651(isoform-parent) psi-mi:"MI:0465"(dip) crc64:3BBB7379DC3B0D07|comment:"No Uniprot Update and Caution removed \" The protein could not be merged with EBI-12907955 because of some conflicts with the protein sequence (features which cannot be shifted).\" -EBI-12907955 no longer exists." - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/05 2017/08/10 rogid:2UolKWXxKFddysaOo70/U/1pI5k9606 rogid:xyMsMwPwid+S2IYb3H0K0pnUc309606 rigid:KwPeFIhAna0H050uZOZfO96jD/o false - sufficient binding region:75-167|sufficient binding region:90-165 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P43357 uniprotkb:O00429-1 intact:EBI-5651459|ensembl:ENSP00000359301|ensembl:ENSP00000473093|uniprotkb:Q6FHI6 intact:EBI-15690834|ensembl:ENSP00000450399 psi-mi:maga3_human(display_long)|uniprotkb:MAGEA3(gene name)|psi-mi:MAGEA3(display_short)|uniprotkb:MAGE3(gene name synonym)|uniprotkb:Antigen MZ2-D(gene name synonym)|uniprotkb:Cancer/testis antigen 1.3(gene name synonym)|uniprotkb:MAGE-3 antigen(gene name synonym) psi-mi:o00429-1(display_long)|uniprotkb:DNM1L(gene name)|psi-mi:DNM1L(display_short)|uniprotkb:DLP1(gene name synonym)|uniprotkb:DRP1(gene name synonym)|uniprotkb:Dnm1p/Vps1p-like protein(gene name synonym)|uniprotkb:Dynamin family member proline-rich carboxyl-terminal domain less(gene name synonym)|uniprotkb:Dynamin-like protein(gene name synonym)|uniprotkb:Dynamin-like protein 4(gene name synonym)|uniprotkb:Dynamin-like protein IV(gene name synonym)|uniprotkb:Dynamin-related protein 1(gene name synonym)|uniprotkb:DLP1F(isoform synonym)|uniprotkb:HdynIV-WT(isoform synonym) psi-mi:"MI:0018"(two hybrid) DeGrado-Warren et al. (2008) pubmed:18330356|imex:IM-8752 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15691278|dip:DIP-201366E|imex:IM-8752-170 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:5BRZ|ensembl:ENSG00000221867(gene)|ensembl:ENST00000370278(transcript)|ensembl:ENST00000598245(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0010955"(negative regulation of protein processing)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0089720"(caspase binding)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|interpro:IPR002190(MAGE protein)|interpro:IPR021072|interpro:IPR030097|interpro:IPR037445|interpro:IPR041898|interpro:IPR041899|rcsb pdb:1QEW|rcsb pdb:4V0P|refseq:XP_011529462.1|refseq:XP_011529463.1|refseq:NP_005353.1|dip:DIP-44886N|refseq:XP_005274733.1|refseq:XP_006724881.1 ensembl:ENSG00000087470(gene)|ensembl:ENST00000549701(transcript)|intact:EBI-724571(isoform-parent) psi-mi:"MI:0465"(dip) crc64:3F5EB13D1C9946A1 - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/05 2017/08/10 rogid:j9zDBF6AxcqLVqpGphlXP2/AlPU9606 rogid:hmh7m80FPMdx6/3eUY6l0IK/AqY9606 rigid:ff2nKGuuAbc30HN4gQWKP9gOHOs false - sufficient binding region:500-697|sufficient binding region:600-736|sufficient binding region:625-736 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O14908-1 uniprotkb:P35638-1 intact:EBI-15691320|ensembl:ENSP00000340698|ensembl:ENSP00000376753|ensembl:ENSP00000466747 intact:EBI-15690897|ensembl:ENSP00000340671|ensembl:ENSP00000447188|ensembl:ENSP00000494844 psi-mi:o14908-1(display_long)|uniprotkb:GIPC1(gene name)|psi-mi:GIPC1(display_short)|uniprotkb:C19orf3(gene name synonym)|uniprotkb:GIPC(gene name synonym)|uniprotkb:RGS19IP1(gene name synonym)|uniprotkb:GAIP C-terminus-interacting protein(gene name synonym)|uniprotkb:RGS-GAIP-interacting protein(gene name synonym)|uniprotkb:RGS19-interacting protein 1(gene name synonym)|uniprotkb:Synectin(gene name synonym)|uniprotkb:Tax interaction protein 2(gene name synonym) psi-mi:p35638-1(display_long)|uniprotkb:DDIT3(gene name)|psi-mi:DDIT3(display_short)|uniprotkb:CHOP(gene name synonym)|uniprotkb:CHOP10(gene name synonym)|uniprotkb:GADD153(gene name synonym)|uniprotkb:C/EBP zeta(gene name synonym)|uniprotkb:C/EBP-homologous protein(gene name synonym)|uniprotkb:C/EBP-homologous protein 10(gene name synonym)|uniprotkb:CCAAT/enhancer-binding protein homologous protein(gene name synonym)|uniprotkb:Growth arrest and DNA damage-inducible protein GADD153(gene name synonym) psi-mi:"MI:0018"(two hybrid) DeGrado-Warren et al. (2008) pubmed:18330356|imex:IM-8752 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15691333|dip:DIP-201389E|imex:IM-8752-172 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-373132(isoform-parent)|ensembl:ENSG00000123159(gene)|ensembl:ENST00000345425(transcript)|ensembl:ENST00000393033(transcript)|ensembl:ENST00000586027(transcript) ensembl:ENSG00000175197(gene)|ensembl:ENST00000346473(transcript)|ensembl:ENST00000547303(transcript)|ensembl:ENST00000623876(transcript)|intact:EBI-742651(isoform-parent) psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/05 2017/08/10 rogid:3lbsiL3bZ/h3ISEr/ryTN7FgbQI9606 rogid:xyMsMwPwid+S2IYb3H0K0pnUc309606 rigid:LH+sSsxx+38GwcXJQQUKZJKReCU false - sufficient binding region:90-165 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P40763-2 uniprotkb:P30626-1 intact:EBI-10692009|ensembl:ENSP00000384943|ensembl:ENSP00000503237|ensembl:ENSP00000503574 intact:EBI-10816740|ensembl:ENSP00000265729 psi-mi:p40763-2(display_long)|uniprotkb:STAT3(gene name)|psi-mi:STAT3(display_short)|uniprotkb:APRF(gene name synonym)|uniprotkb:Acute-phase response factor(gene name synonym) psi-mi:p30626-1(display_long)|uniprotkb:22 kDa protein(gene name synonym)|uniprotkb:CP-22(gene name synonym)|uniprotkb:V19(gene name synonym)|uniprotkb:SRI(gene name)|psi-mi:SRI(display_short) psi-mi:"MI:0018"(two hybrid) DeGrado-Warren et al. (2008) pubmed:18330356|imex:IM-8752 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15691369|dip:DIP-201374E|imex:IM-8752-78 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000168610(gene)|ensembl:ENST00000404395(transcript)|ensembl:ENST00000677723(transcript)|ensembl:ENST00000679014(transcript)|intact:EBI-518675(isoform-parent)|uniprotkb:P40763-2(isoform-parent) intact:EBI-750459(isoform-parent)|ensembl:ENSG00000075142(gene)|ensembl:ENST00000265729(transcript) psi-mi:"MI:0465"(dip) isoform-comment:Contains a phosphotyrosine at position 704. - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/05 2017/08/10 rogid:/1UcPsO8RrgzHRF25zP2b9DTN0M9606 rogid:upE31IMimaotkgnYa7HYr7EYAxc9606 rigid:5q3ngRv2LxqCRe0vCokXS++ceQw false - sufficient binding region:26-163 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P81877 uniprotkb:O43679-1 intact:EBI-748077|uniprotkb:Q8N2Q2|uniprotkb:Q9BWW6|uniprotkb:Q9Y4T7|uniprotkb:B7Z2L9|uniprotkb:E9PDA8|uniprotkb:B2R5W1|uniprotkb:B7Z1J2|uniprotkb:B7Z665|uniprotkb:D6RH18|uniprotkb:E9PB74|intact:EBI-28967061|ensembl:ENSP00000322977 intact:EBI-15691011|ensembl:ENSP00000306772 psi-mi:ssbp2_human(display_long)|uniprotkb:Sequence-specific single-stranded-DNA-binding protein 2(gene name synonym)|uniprotkb:SSBP2(gene name)|psi-mi:SSBP2(display_short)|uniprotkb:SSDP2(gene name synonym) psi-mi:o43679-1(display_long)|uniprotkb:LDB2(gene name)|psi-mi:LDB2(display_short)|uniprotkb:CLIM1(gene name synonym)|uniprotkb:Carboxyl-terminal LIM domain-binding protein 1(gene name synonym)|uniprotkb:LIM domain-binding factor CLIM1(gene name synonym)|uniprotkb:CLIM1a(isoform synonym)|uniprotkb:a(isoform synonym) psi-mi:"MI:0018"(two hybrid) DeGrado-Warren et al. (2008) pubmed:18330356|imex:IM-8752 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15691351|dip:DIP-201382E|imex:IM-8752-174 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSP00000322977|ensembl:ENST00000505980|ensembl:ENSP00000423969|ensembl:ENST00000509053|ensembl:ENSP00000422961|ensembl:ENST00000514493|ensembl:ENSP00000426183|ensembl:ENST00000515395|ensembl:ENSP00000424657|refseq:NP_001243661.1|refseq:NP_036578.2|refseq:NP_001243665.1|refseq:NP_001243663.1|refseq:NP_001243664.1|refseq:NP_001243662.1|ensembl:ENSG00000145687(gene)|ensembl:ENST00000320672(transcript)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR006594(LisH dimerisation motif)|interpro:IPR008116(Sequence-specific single-strand DNA-binding protein)|mint:P81877|rcsb pdb:6IWV|rcsb pdb:6TYD|dip:DIP-29459N intact:EBI-2865580(isoform-parent)|ensembl:ENSG00000169744(gene)|ensembl:ENST00000304523(transcript) psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/05 2017/08/10 rogid:CMmZPTurp1G6Y2q7GP/pTMlFM549606 rogid:3p/spcR1ariBlpLJczJxP5Mfi9w9606 rigid:BEhSM4cpGThCsZ6IyREbgsz1uZA false - sufficient binding region:1-300 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q969G2 uniprotkb:O43679-1 intact:EBI-2865388|uniprotkb:Q8NHM1|uniprotkb:Q969W2|uniprotkb:Q8TCJ1|uniprotkb:Q8NHE0|uniprotkb:Q8WWX2|ensembl:ENSP00000263726 intact:EBI-15691011|ensembl:ENSP00000306772 psi-mi:lhx4_human(display_long)|uniprotkb:LHX4(gene name)|psi-mi:LHX4(display_short) psi-mi:o43679-1(display_long)|uniprotkb:LDB2(gene name)|psi-mi:LDB2(display_short)|uniprotkb:CLIM1(gene name synonym)|uniprotkb:Carboxyl-terminal LIM domain-binding protein 1(gene name synonym)|uniprotkb:LIM domain-binding factor CLIM1(gene name synonym)|uniprotkb:CLIM1a(isoform synonym)|uniprotkb:a(isoform synonym) psi-mi:"MI:0018"(two hybrid) DeGrado-Warren et al. (2008) pubmed:18330356|imex:IM-8752 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15691409|dip:DIP-201367E|imex:IM-8752-176 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_203129.1|dip:DIP-29454N|ensembl:ENSG00000121454(gene)|ensembl:ENST00000263726(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001890"(placenta development)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0008327"(methyl-CpG binding)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0021526"(medial motor column neuron differentiation)|go:"GO:0030182"(neuron differentiation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|mint:Q969G2|rcsb pdb:5HOD|reactome:R-HSA-9010553 intact:EBI-2865580(isoform-parent)|ensembl:ENSG00000169744(gene)|ensembl:ENST00000304523(transcript) psi-mi:"MI:0465"(dip) crc64:6499F38E78B79FD1 - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/05 2017/08/10 rogid:dCB3WgIBMdi0nNvaCFaioh+F9sw9606 rogid:3p/spcR1ariBlpLJczJxP5Mfi9w9606 rigid:Rsb3R1jHbDZkeHbr+0F9MPFjwq4 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P04792 uniprotkb:P02511 intact:EBI-352682|uniprotkb:Q6FI47|uniprotkb:Q96C20|uniprotkb:Q96EI7|uniprotkb:Q9UC34|uniprotkb:Q9UC35|uniprotkb:Q9UC36|uniprotkb:Q9UC31|ensembl:ENSP00000248553|uniprotkb:B2R4N8 intact:EBI-739060|uniprotkb:O43416|uniprotkb:B0YIX0|uniprotkb:Q9UC37|uniprotkb:Q9UC38|uniprotkb:Q9UC39|uniprotkb:Q9UC40|uniprotkb:Q9UC41|ensembl:ENSP00000227251|ensembl:ENSP00000433560|ensembl:ENSP00000434247|ensembl:ENSP00000435931|ensembl:ENSP00000436051|ensembl:ENSP00000436089|ensembl:ENSP00000437149|ensembl:ENSP00000483554|ensembl:ENSP00000498735|ensembl:ENSP00000499082 psi-mi:hspb1_human(display_long)|uniprotkb:HSPB1(gene name)|psi-mi:HSPB1(display_short)|uniprotkb:HSP27(gene name synonym)|uniprotkb:HSP28(gene name synonym)|uniprotkb:Heat shock 27 kDa protein(gene name synonym)|uniprotkb:Stress-responsive protein 27(gene name synonym)|uniprotkb:Estrogen-regulated 24 kDa protein(gene name synonym)|uniprotkb:28 kDa heat shock protein(gene name synonym) psi-mi:cryab_human(display_long)|uniprotkb:CRYAB(gene name)|psi-mi:CRYAB(display_short)|uniprotkb:CRYA2(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-27(gene name synonym)|uniprotkb:"Alpha(B)-crystallin"(gene name synonym)|uniprotkb:Rosenthal fiber component(gene name synonym)|uniprotkb:Heat shock protein beta-5(gene name synonym)|uniprotkb:HSPB5(gene name synonym) psi-mi:"MI:0018"(two hybrid) DeGrado-Warren et al. (2008) pubmed:18330356|imex:IM-8752 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15691387|dip:DIP-70013E|imex:IM-8752-116 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001531.1|ensembl:ENSG00000106211(gene)|ensembl:ENST00000248553(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0001895"(retina homeostasis)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0003723"(RNA binding)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008426"(protein kinase C inhibitor activity)|go:"GO:0009615"(response to virus)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030018"(Z disc)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035924"(cellular response to vascular endothelial growth factor stimulus)|go:"GO:0038033"(positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070527"(platelet aggregation)|go:"GO:0099641"(anterograde axonal protein transport)|go:"GO:1902176"(negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1904115"(axon cytoplasm)|go:"GO:2001028"(positive regulation of endothelial cell chemotaxis)|interpro:IPR001436(Alpha crystallin/Heat shock protein)|interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR037876|mint:P04792|rcsb pdb:2N3J|rcsb pdb:3Q9P|rcsb pdb:3Q9Q|rcsb pdb:4MJH|rcsb pdb:6DV5|rcsb pdb:6GJH|reactome:R-HSA-4420097|reactome:R-HSA-450408|reactome:R-HSA-5687128|reactome:R-HSA-9009391|dip:DIP-412N ensembl:ENSG00000109846(gene)|ensembl:ENST00000227251(transcript)|ensembl:ENST00000526180(transcript)|ensembl:ENST00000527899(transcript)|ensembl:ENST00000527950(transcript)|ensembl:ENST00000531198(transcript)|ensembl:ENST00000533475(transcript)|ensembl:ENST00000533879(transcript)|ensembl:ENST00000616970(transcript)|ensembl:ENST00000650687(transcript)|ensembl:ENST00000651164(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001666"(response to hypoxia)|go:"GO:0002088"(lens development in camera-type eye)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0006936"(muscle contraction)|go:"GO:0007021"(tubulin complex assembly)|go:"GO:0007517"(muscle organ development)|go:"GO:0008017"(microtubule binding)|go:"GO:0009986"(cell surface)|go:"GO:0010259"(multicellular organism aging)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010941"(regulation of cell death)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030018"(Z disc)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030424"(axon)|go:"GO:0031109"(microtubule polymerization or depolymerization)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031430"(M band)|go:"GO:0032355"(response to estradiol)|go:"GO:0032387"(negative regulation of intracellular transport)|go:"GO:0032432"(actin filament bundle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043197"(dendritic spine)|go:"GO:0043204"(perikaryon)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051403"(stress-activated MAPK cascade)|go:"GO:0060561"(apoptotic process involved in morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0097060"(synaptic membrane)|go:"GO:0097512"(cardiac myofibril)|go:"GO:1905907"(negative regulation of amyloid fibril formation)|go:"GO:2000378"(negative regulation of reactive oxygen species metabolic process)|interpro:IPR001436(Alpha crystallin/Heat shock protein)|interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR003090(Alpha-crystallin, N-terminal)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR037882|mint:P02511|rcsb pdb:2KLR|rcsb pdb:2N0K|rcsb pdb:2WJ7|rcsb pdb:2Y1Y|rcsb pdb:2Y1Z|rcsb pdb:2YGD|rcsb pdb:3J07|rcsb pdb:2Y22|rcsb pdb:3L1G|rcsb pdb:3SGM|rcsb pdb:3SGN|rcsb pdb:3SGO|rcsb pdb:3SGP|rcsb pdb:3SGR|rcsb pdb:3SGS|rcsb pdb:4M5S|rcsb pdb:4M5T|rcsb pdb:5VVV|rcsb pdb:6BP9|reactome:R-HSA-3371571|refseq:NP_001876.1|refseq:XP_011540910.1|refseq:NP_001276736.1|refseq:NP_001276737.1|dip:DIP-35017N psi-mi:"MI:0465"(dip) crc64:1B4DC44A6F6606D5 crc64:AE08BED46B7849CB full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/05 2017/08/10 rogid:vrDXIdzP30aHSDLHOh2D4x54eJY9606 rogid:495Z42oQhkAUdADrAEOKIC5oICo9606 rigid:HlIost5vRGNZhOzHD7XSsVsRheE false - sufficient binding region:1-78|sufficient binding region:3-175|sufficient binding region:60-170 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q86SX3 uniprotkb:P35638-1 intact:EBI-3247115|ensembl:ENSP00000376308|uniprotkb:Q86TT5|uniprotkb:Q9H7H4|uniprotkb:Q86TT3|uniprotkb:Q96B41|uniprotkb:B5MDG3|uniprotkb:Q86TT4|uniprotkb:E9PAQ4 intact:EBI-15690897|ensembl:ENSP00000340671|ensembl:ENSP00000447188|ensembl:ENSP00000494844 psi-mi:tedc1_human(display_long)|uniprotkb:TEDC1(gene name)|psi-mi:TEDC1(display_short)|uniprotkb:C14orf80(gene name synonym) psi-mi:p35638-1(display_long)|uniprotkb:DDIT3(gene name)|psi-mi:DDIT3(display_short)|uniprotkb:CHOP(gene name synonym)|uniprotkb:CHOP10(gene name synonym)|uniprotkb:GADD153(gene name synonym)|uniprotkb:C/EBP zeta(gene name synonym)|uniprotkb:C/EBP-homologous protein(gene name synonym)|uniprotkb:C/EBP-homologous protein 10(gene name synonym)|uniprotkb:CCAAT/enhancer-binding protein homologous protein(gene name synonym)|uniprotkb:Growth arrest and DNA damage-inducible protein GADD153(gene name synonym) psi-mi:"MI:0018"(two hybrid) DeGrado-Warren et al. (2008) pubmed:18330356|imex:IM-8752 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15691425|dip:DIP-201392E|imex:IM-8752-98 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001128347.1|ensembl:ENSG00000185347(gene)|ensembl:ENST00000392523(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005814"(centriole)|go:"GO:0005929"(cilium)|go:"GO:0045880"(positive regulation of smoothened signaling pathway)|interpro:IPR028100|interpro:IPR043535|interpro:IPR027996|refseq:NP_001128348.1|refseq:NP_001185912.1|refseq:NP_001128349.1|dip:DIP-62062N ensembl:ENSG00000175197(gene)|ensembl:ENST00000346473(transcript)|ensembl:ENST00000547303(transcript)|ensembl:ENST00000623876(transcript)|intact:EBI-742651(isoform-parent) psi-mi:"MI:0465"(dip) crc64:3E34FACE82E0EACF - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/05 2017/08/10 rogid:TEv3WjggyWs0uRE4CRaeSB7Wmfk9606 rogid:xyMsMwPwid+S2IYb3H0K0pnUc309606 rigid:gfQU2Pf6gRlNIUk3pdEDHHZsaOM false - sufficient binding region:75-167|sufficient binding region:90-165 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q01518 uniprotkb:P47712 intact:EBI-2808398|ensembl:ENSP00000361878|ensembl:ENSP00000361883|ensembl:ENSP00000361891|uniprotkb:Q6I9U6|uniprotkb:Q5T0S2|uniprotkb:Q53HR7|uniprotkb:Q5T0S1 intact:EBI-1044090|uniprotkb:Q29R80|ensembl:ENSP00000356436|uniprotkb:B1AKG4 psi-mi:cap1_human(display_long)|uniprotkb:CAP1(gene name)|psi-mi:CAP1(display_short)|uniprotkb:CAP(gene name synonym) psi-mi:pa24a_human(display_long)|uniprotkb:PLA2G4A(gene name)|psi-mi:PLA2G4A(display_short)|uniprotkb:CPLA2(gene name synonym)|uniprotkb:PLA2G4(gene name synonym)|uniprotkb:Phospholipase A2 group IVA(gene name synonym) psi-mi:"MI:0018"(two hybrid) DeGrado-Warren et al. (2008) pubmed:18330356|imex:IM-8752 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15691445|dip:DIP-201375E|imex:IM-8752-190 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131236(gene)|ensembl:ENST00000372792(transcript)|ensembl:ENST00000372797(transcript)|ensembl:ENST00000372805(transcript)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0003779"(actin binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007165"(signal transduction)|go:"GO:0007190"(activation of adenylate cyclase activity)|go:"GO:0008179"(adenylate cyclase binding)|go:"GO:0019933"(cAMP-mediated signaling)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0045761"(regulation of adenylate cyclase activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001837(Adenylate cyclase-associated CAP)|interpro:IPR006599(CARP motif)|interpro:IPR013912(Adenylate cyclase-associated CAP, C-terminal)|interpro:IPR013992(Adenylate cyclase-associated CAP, N-terminal)|interpro:IPR016098(Cyclase-associated protein CAP/septum formation inhibitor MinC, C-terminal)|interpro:IPR017901|interpro:IPR018106|interpro:IPR028415|interpro:IPR028417|go:"GO:0001667"(ameboidal-type cell migration)|interpro:IPR036222|interpro:IPR036223|mint:Q01518|rcsb pdb:1K8F|reactome:R-HSA-114608|reactome:R-HSA-428890|reactome:R-HSA-6798695|refseq:XP_011538811.1|refseq:XP_011538812.1|refseq:XP_011538813.1|refseq:XP_011538814.1|refseq:XP_011538815.1|refseq:XP_011538816.1|refseq:XP_011538817.1|refseq:NP_001099000.1|refseq:NP_006358.1|refseq:XP_016855556.1|refseq:XP_016855557.1|refseq:XP_016855558.1|refseq:XP_016855559.1|refseq:XP_016855560.1|refseq:XP_016855561.1|refseq:XP_005270425.1|dip:DIP-62063N refseq:NP_077734.1|go:"GO:0102567"|go:"GO:0102568"|go:"GO:1902387"(ceramide 1-phosphate binding)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR002642(Lysophospholipase, catalytic region)|interpro:IPR016035(Acyl transferase/acyl hydrolase/lysophospholipase)|interpro:IPR035892|interpro:IPR041847|rcsb pdb:1BCI|rcsb pdb:1CJY|rcsb pdb:1RLW|reactome:R-HSA-111995|reactome:R-HSA-1482788|reactome:R-HSA-1482798|reactome:R-HSA-1482801|reactome:R-HSA-1482839|reactome:R-HSA-1482922|reactome:R-HSA-1482925|reactome:R-HSA-1483115|reactome:R-HSA-1483166|reactome:R-HSA-2142753|reactome:R-HSA-418592|reactome:R-HSA-432142|reactome:R-HSA-6811436|ensembl:ENSG00000116711(gene)|ensembl:ENST00000367466(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001516"(prostaglandin biosynthetic process)|go:"GO:0002827"(positive regulation of T-helper 1 type immune response)|go:"GO:0004622"(lysophospholipase activity)|go:"GO:0004623"(phospholipase A2 activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006071"(glycerol metabolic process)|go:"GO:0006640"(monoacylglycerol biosynthetic process)|go:"GO:0006663"(platelet activating factor biosynthetic process)|go:"GO:0008374"(O-acyltransferase activity)|go:"GO:0010314"(phosphatidylinositol-5-phosphate binding)|go:"GO:0010572"(positive regulation of platelet activation)|go:"GO:0019369"(arachidonic acid metabolic process)|go:"GO:0019370"(leukotriene biosynthetic process)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0032308"(positive regulation of prostaglandin secretion)|go:"GO:0034478"(phosphatidylglycerol catabolic process)|go:"GO:0034638"(phosphatidylcholine catabolic process)|go:"GO:0036151"(phosphatidylcholine acyl-chain remodeling)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043032"(positive regulation of macrophage activation)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046475"(glycerophospholipid catabolic process)|go:"GO:0047498"(calcium-dependent phospholipase A2 activity)|go:"GO:0047499"(calcium-independent phospholipase A2 activity)|go:"GO:0050482"(arachidonic acid secretion)|go:"GO:0070273"(phosphatidylinositol-4-phosphate binding)|go:"GO:0071236"(cellular response to antibiotic)|go:"GO:0102545"(phosphatidyl phospholipase B activity)|go:"GO:0006690"(icosanoid metabolic process)|refseq:NP_001298122.1|refseq:XP_011507944.1|dip:DIP-40991N psi-mi:"MI:0465"(dip) crc64:7789D1FAC0D1AB7B crc64:EE71CA0EBE617856 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/05 2017/08/10 rogid:BXrQm0u+e0xVOl2b+A18GrZy5Eg9606 rogid:D/yM7EFWP6xaMQ//7wutJS5D3jw9606 rigid:F6o2Q8pGycCONTOQSZJ0NRULpMs false - sufficient binding region:1-121|sufficient binding region:1-129 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q13137-2 uniprotkb:P30626-1 intact:EBI-15691465|ensembl:ENSP00000406974 intact:EBI-10816740|ensembl:ENSP00000265729 psi-mi:q13137-2(display_long)|uniprotkb:CALCOCO2(gene name)|psi-mi:CALCOCO2(display_short)|uniprotkb:NDP52(gene name synonym)|uniprotkb:Antigen nuclear dot 52 kDa protein(gene name synonym)|uniprotkb:Nuclear domain 10 protein NDP52(gene name synonym)|uniprotkb:Nuclear dot protein 52(gene name synonym) psi-mi:p30626-1(display_long)|uniprotkb:22 kDa protein(gene name synonym)|uniprotkb:CP-22(gene name synonym)|uniprotkb:V19(gene name synonym)|uniprotkb:SRI(gene name)|psi-mi:SRI(display_short) psi-mi:"MI:0018"(two hybrid) DeGrado-Warren et al. (2008) pubmed:18330356|imex:IM-8752 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15691475|dip:DIP-201368E|imex:IM-8752-192 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000136436(gene)|ensembl:ENST00000416445(transcript)|intact:EBI-739580(isoform-parent) intact:EBI-750459(isoform-parent)|ensembl:ENSG00000075142(gene)|ensembl:ENST00000265729(transcript) psi-mi:"MI:0465"(dip) isoform-comment:No experimental confirmation available. - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/05 2017/08/10 rogid:0iICYX3zitg/x2133oj2ZK51LkU9606 rogid:upE31IMimaotkgnYa7HYr7EYAxc9606 rigid:2srskC0jSKHFpLNVFoXKx3grR0A false - sufficient binding region:26-163 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P43355 uniprotkb:O00429-1 intact:EBI-740978|ensembl:ENSP00000349085|uniprotkb:O00346|uniprotkb:B2RC81 intact:EBI-15690834|ensembl:ENSP00000450399 psi-mi:maga1_human(display_long)|uniprotkb:MAGE-1 antigen(gene name synonym)|uniprotkb:Antigen MZ2-E(gene name synonym)|uniprotkb:Cancer/testis antigen 1.1(gene name synonym)|uniprotkb:MAGEA1(gene name)|psi-mi:MAGEA1(display_short)|uniprotkb:MAGE1(gene name synonym)|uniprotkb:MAGE1A(gene name synonym) psi-mi:o00429-1(display_long)|uniprotkb:DNM1L(gene name)|psi-mi:DNM1L(display_short)|uniprotkb:DLP1(gene name synonym)|uniprotkb:DRP1(gene name synonym)|uniprotkb:Dnm1p/Vps1p-like protein(gene name synonym)|uniprotkb:Dynamin family member proline-rich carboxyl-terminal domain less(gene name synonym)|uniprotkb:Dynamin-like protein(gene name synonym)|uniprotkb:Dynamin-like protein 4(gene name synonym)|uniprotkb:Dynamin-like protein IV(gene name synonym)|uniprotkb:Dynamin-related protein 1(gene name synonym)|uniprotkb:DLP1F(isoform synonym)|uniprotkb:HdynIV-WT(isoform synonym) psi-mi:"MI:0018"(two hybrid) DeGrado-Warren et al. (2008) pubmed:18330356|imex:IM-8752 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15691493|dip:DIP-201391E|imex:IM-8752-156 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004979.3|ensembl:ENSG00000198681(gene)|ensembl:ENST00000356661(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|interpro:IPR002190(MAGE protein)|interpro:IPR021072|interpro:IPR030093|interpro:IPR037445|interpro:IPR041898|interpro:IPR041899|rcsb pdb:1W72|rcsb pdb:3BO8|dip:DIP-54794N ensembl:ENSG00000087470(gene)|ensembl:ENST00000549701(transcript)|intact:EBI-724571(isoform-parent) psi-mi:"MI:0465"(dip) crc64:544EEB1F9F4E9D33 - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/05 2017/08/10 rogid:6XW3mnTNM3yvOtXmiFbU8Uz3hjA9606 rogid:hmh7m80FPMdx6/3eUY6l0IK/AqY9606 rigid:TG6srazh8XY8aGSJM/T+wXQ6nRw false - sufficient binding region:500-697|sufficient binding region:600-736 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P31350-1 uniprotkb:O00429-1 intact:EBI-15691513|ensembl:ENSP00000302955|ensembl:ENSP00000493399 intact:EBI-15690834|ensembl:ENSP00000450399 psi-mi:p31350-1(display_long)|uniprotkb:RRM2(gene name)|psi-mi:RRM2(display_short)|uniprotkb:RR2(gene name synonym)|uniprotkb:Ribonucleotide reductase small chain(gene name synonym)|uniprotkb:Ribonucleotide reductase small subunit(gene name synonym) psi-mi:o00429-1(display_long)|uniprotkb:DNM1L(gene name)|psi-mi:DNM1L(display_short)|uniprotkb:DLP1(gene name synonym)|uniprotkb:DRP1(gene name synonym)|uniprotkb:Dnm1p/Vps1p-like protein(gene name synonym)|uniprotkb:Dynamin family member proline-rich carboxyl-terminal domain less(gene name synonym)|uniprotkb:Dynamin-like protein(gene name synonym)|uniprotkb:Dynamin-like protein 4(gene name synonym)|uniprotkb:Dynamin-like protein IV(gene name synonym)|uniprotkb:Dynamin-related protein 1(gene name synonym)|uniprotkb:DLP1F(isoform synonym)|uniprotkb:HdynIV-WT(isoform synonym) psi-mi:"MI:0018"(two hybrid) DeGrado-Warren et al. (2008) pubmed:18330356|imex:IM-8752 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15691521|dip:DIP-201376E|imex:IM-8752-118 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2339245(isoform-parent)|ensembl:ENSG00000171848(gene)|ensembl:ENST00000304567(transcript)|ensembl:ENST00000641198(transcript) ensembl:ENSG00000087470(gene)|ensembl:ENST00000549701(transcript)|intact:EBI-724571(isoform-parent) psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/05 2017/08/10 rogid:vkkD9wGSPnsXX89dIQ53fhLD7uI9606 rogid:hmh7m80FPMdx6/3eUY6l0IK/AqY9606 rigid:IH87jmmC35trALvjkQVc45YiUys false - sufficient binding region:500-697|sufficient binding region:600-736|sufficient binding region:625-736 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q14141 uniprotkb:Q99719-1 intact:EBI-745901|uniprotkb:Q5JTK0|uniprotkb:Q969W5|uniprotkb:Q96A13|uniprotkb:Q96GR1|uniprotkb:Q96P86|uniprotkb:Q96P87|intact:EBI-1047521|ensembl:ENSP00000341524 intact:EBI-15690930|ensembl:ENSP00000391311 psi-mi:sept6_human(display_long)|uniprotkb:SEPTIN6(gene name)|psi-mi:SEPTIN6(display_short)|uniprotkb:KIAA0128(gene name synonym)|uniprotkb:SEP2(gene name synonym)|uniprotkb:SEPT6(gene name synonym) psi-mi:q99719-1(display_long)|uniprotkb:SEPTIN5(gene name)|psi-mi:SEPTIN5(display_short)|uniprotkb:Cell division control-related protein 1(gene name synonym)|uniprotkb:PNUTL1(gene name synonym)|uniprotkb:Peanut-like protein 1(gene name synonym)|uniprotkb:SEPT5(gene name synonym) psi-mi:"MI:0018"(two hybrid) DeGrado-Warren et al. (2008) pubmed:18330356|imex:IM-8752 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15691543|dip:DIP-201369E|imex:IM-8752-158 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000125354(gene)|ensembl:ENST00000343984(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0000776"(kinetochore)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005819"(spindle)|go:"GO:0005940"(septin ring)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030154"(cell differentiation)|go:"GO:0030496"(midbody)|go:"GO:0031105"(septin complex)|go:"GO:0032153"(cell division site)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032173"(septin collar)|go:"GO:0034613"(cellular protein localization)|go:"GO:0043679"(axon terminus)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis)|go:"GO:0097227"(sperm annulus)|interpro:IPR016491(Septin)|interpro:IPR027417|interpro:IPR030379|interpro:IPR030644|mint:Q14141|rcsb pdb:2QAG|rcsb pdb:6UPA|rcsb pdb:6WBP|refseq:NP_055944.2|refseq:NP_665798.1|refseq:NP_665799.1|refseq:NP_665801.1|refseq:XP_006724813.1|dip:DIP-38218N ensembl:ENSG00000184702(gene)|ensembl:ENST00000455784(transcript)|intact:EBI-373345(isoform-parent) psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/05 2017/08/10 rogid:gH1JHXyE/7o3I8i4ZS3bMoF7zvU9606 rogid:kubhD1O+WmJeDWTlX+rcjpP9yRc9606 rigid:onUUjwC+FyLQWnGgnvyVM+sdkJU false - sufficient binding region:25-290|sufficient binding region:30-330 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q99961-1 uniprotkb:O00429-1 intact:EBI-15691604|ensembl:ENSP00000269886 intact:EBI-15690834|ensembl:ENSP00000450399 psi-mi:q99961-1(display_long)|uniprotkb:SH3GL1(gene name)|psi-mi:SH3GL1(display_short)|uniprotkb:CNSA1(gene name synonym)|uniprotkb:SH3D2B(gene name synonym)|uniprotkb:EEN fusion partner of MLL(gene name synonym)|uniprotkb:Endophilin-2(gene name synonym)|uniprotkb:Extra eleven-nineteen leukemia fusion gene protein(gene name synonym)|uniprotkb:SH3 domain protein 2B(gene name synonym)|uniprotkb:SH3 domain-containing GRB2-like protein 1(gene name synonym) psi-mi:o00429-1(display_long)|uniprotkb:DNM1L(gene name)|psi-mi:DNM1L(display_short)|uniprotkb:DLP1(gene name synonym)|uniprotkb:DRP1(gene name synonym)|uniprotkb:Dnm1p/Vps1p-like protein(gene name synonym)|uniprotkb:Dynamin family member proline-rich carboxyl-terminal domain less(gene name synonym)|uniprotkb:Dynamin-like protein(gene name synonym)|uniprotkb:Dynamin-like protein 4(gene name synonym)|uniprotkb:Dynamin-like protein IV(gene name synonym)|uniprotkb:Dynamin-related protein 1(gene name synonym)|uniprotkb:DLP1F(isoform synonym)|uniprotkb:HdynIV-WT(isoform synonym) psi-mi:"MI:0018"(two hybrid) DeGrado-Warren et al. (2008) pubmed:18330356|imex:IM-8752 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15691617|dip:DIP-201377E|imex:IM-8752-120 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-697911(isoform-parent)|ensembl:ENSG00000141985(gene)|ensembl:ENST00000269886(transcript) ensembl:ENSG00000087470(gene)|ensembl:ENST00000549701(transcript)|intact:EBI-724571(isoform-parent) psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/05 2017/08/10 rogid:Qzz+R0MGXEpZ6G0xoPglUBKBIfk9606 rogid:hmh7m80FPMdx6/3eUY6l0IK/AqY9606 rigid:ecvPL0lSeWdxlhnnZ/pJ/uxgSn4 false - sufficient binding region:500-697|sufficient binding region:600-736 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q96NA2-1 uniprotkb:O43679-1 intact:EBI-15691579|ensembl:ENSP00000301336|ensembl:ENSP00000481849 intact:EBI-15691011|ensembl:ENSP00000306772 psi-mi:q96na2-1(display_long)|uniprotkb:RILP(gene name)|psi-mi:RILP(display_short)|uniprotkb:PP10141(orf name) psi-mi:o43679-1(display_long)|uniprotkb:LDB2(gene name)|psi-mi:LDB2(display_short)|uniprotkb:CLIM1(gene name synonym)|uniprotkb:Carboxyl-terminal LIM domain-binding protein 1(gene name synonym)|uniprotkb:LIM domain-binding factor CLIM1(gene name synonym)|uniprotkb:CLIM1a(isoform synonym)|uniprotkb:a(isoform synonym) psi-mi:"MI:0018"(two hybrid) DeGrado-Warren et al. (2008) pubmed:18330356|imex:IM-8752 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15691586|dip:DIP-201370E|imex:IM-8752-178 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2856119(isoform-parent)|ensembl:ENSG00000167705(gene)|ensembl:ENSG00000274145(gene)|ensembl:ENST00000301336(transcript)|ensembl:ENST00000622136(transcript) intact:EBI-2865580(isoform-parent)|ensembl:ENSG00000169744(gene)|ensembl:ENST00000304523(transcript) psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/05 2017/08/10 rogid:dBBOnpVleCSq8//uqicphTGykw09606 rogid:3p/spcR1ariBlpLJczJxP5Mfi9w9606 rigid:+L1fD1JQ+PRHk0CypdjBEpLfIdY false - sufficient binding region:1-300 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P30626-1 uniprotkb:P30626-1 intact:EBI-10816740|ensembl:ENSP00000265729 intact:EBI-10816740|ensembl:ENSP00000265729 psi-mi:p30626-1(display_long)|uniprotkb:22 kDa protein(gene name synonym)|uniprotkb:CP-22(gene name synonym)|uniprotkb:V19(gene name synonym)|uniprotkb:SRI(gene name)|psi-mi:SRI(display_short) psi-mi:p30626-1(display_long)|uniprotkb:22 kDa protein(gene name synonym)|uniprotkb:CP-22(gene name synonym)|uniprotkb:V19(gene name synonym)|uniprotkb:SRI(gene name)|psi-mi:SRI(display_short) psi-mi:"MI:0018"(two hybrid) DeGrado-Warren et al. (2008) pubmed:18330356|imex:IM-8752 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15691563|dip:DIP-201384E|imex:IM-8752-136 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-750459(isoform-parent)|ensembl:ENSG00000075142(gene)|ensembl:ENST00000265729(transcript) intact:EBI-750459(isoform-parent)|ensembl:ENSG00000075142(gene)|ensembl:ENST00000265729(transcript) psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/05 2017/08/10 rogid:upE31IMimaotkgnYa7HYr7EYAxc9606 rogid:upE31IMimaotkgnYa7HYr7EYAxc9606 rigid:yuChTBuj+PCNsWydceSY1GWliYs false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q96CN5 uniprotkb:Q96EK4 intact:EBI-2805176|ensembl:ENSP00000306760 intact:EBI-1790529|uniprotkb:O94795|uniprotkb:A8K002|uniprotkb:A4UCT5|ensembl:ENSP00000304689 psi-mi:lrc45_human(display_long)|uniprotkb:LRRC45(gene name)|psi-mi:LRRC45(display_short) psi-mi:tha11_human(display_long)|uniprotkb:THAP11(gene name)|psi-mi:THAP11(display_short)|uniprotkb:HRIHFB2206(orf name) psi-mi:"MI:0018"(two hybrid) DeGrado-Warren et al. (2008) pubmed:18330356|imex:IM-8752 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15691637|dip:DIP-201393E|imex:IM-8752-138 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000169683(gene)|ensembl:ENST00000306688(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR032675|refseq:NP_659436.1|dip:DIP-29482N refseq:NP_065190.2|dip:DIP-46732N|ensembl:ENSP00000304689|ensembl:ENSG00000168286(gene)|ensembl:ENST00000303596(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|interpro:IPR006612(Zinc finger, C2CH-type)|rcsb pdb:2LAU|rcsb pdb:5AJS psi-mi:"MI:0465"(dip) crc64:27F5D210721459FB crc64:25235D20CB54D8C2 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/05 2017/08/10 rogid:cuIAlpH4zLJ1La+TtOc2x4c2dMI9606 rogid:qzl6RN2xlTuDBruwyKLyDTNRCKE9606 rigid:/X5+dQ4Usq+x+r6lKd2qYytbF2g false - sufficient binding region:196-314|sufficient binding region:230-314 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q96GS4 uniprotkb:P47712 intact:EBI-10193358|uniprotkb:Q9NXW8|uniprotkb:Q53HS4|ensembl:ENSP00000373669 intact:EBI-1044090|uniprotkb:Q29R80|ensembl:ENSP00000356436|uniprotkb:B1AKG4 psi-mi:borc6_human(display_long)|uniprotkb:BORCS6(gene name)|psi-mi:BORCS6(display_short)|uniprotkb:C17orf59(gene name synonym)|uniprotkb:Lysosome-dispersing protein(gene name synonym) psi-mi:pa24a_human(display_long)|uniprotkb:PLA2G4A(gene name)|psi-mi:PLA2G4A(display_short)|uniprotkb:CPLA2(gene name synonym)|uniprotkb:PLA2G4(gene name synonym)|uniprotkb:Phospholipase A2 group IVA(gene name synonym) psi-mi:"MI:0018"(two hybrid) DeGrado-Warren et al. (2008) pubmed:18330356|imex:IM-8752 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15691657|dip:DIP-201386E|imex:IM-8752-160 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060092.2|ensembl:ENSG00000196544(gene)|ensembl:ENST00000389017(transcript)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0032418"(lysosome localization)|go:"GO:0042802"(identical protein binding)|go:"GO:0099078"(BORC complex)|interpro:IPR019314|dip:DIP-29465N refseq:NP_077734.1|go:"GO:0102567"|go:"GO:0102568"|go:"GO:1902387"(ceramide 1-phosphate binding)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR002642(Lysophospholipase, catalytic region)|interpro:IPR016035(Acyl transferase/acyl hydrolase/lysophospholipase)|interpro:IPR035892|interpro:IPR041847|rcsb pdb:1BCI|rcsb pdb:1CJY|rcsb pdb:1RLW|reactome:R-HSA-111995|reactome:R-HSA-1482788|reactome:R-HSA-1482798|reactome:R-HSA-1482801|reactome:R-HSA-1482839|reactome:R-HSA-1482922|reactome:R-HSA-1482925|reactome:R-HSA-1483115|reactome:R-HSA-1483166|reactome:R-HSA-2142753|reactome:R-HSA-418592|reactome:R-HSA-432142|reactome:R-HSA-6811436|ensembl:ENSG00000116711(gene)|ensembl:ENST00000367466(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001516"(prostaglandin biosynthetic process)|go:"GO:0002827"(positive regulation of T-helper 1 type immune response)|go:"GO:0004622"(lysophospholipase activity)|go:"GO:0004623"(phospholipase A2 activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006071"(glycerol metabolic process)|go:"GO:0006640"(monoacylglycerol biosynthetic process)|go:"GO:0006663"(platelet activating factor biosynthetic process)|go:"GO:0008374"(O-acyltransferase activity)|go:"GO:0010314"(phosphatidylinositol-5-phosphate binding)|go:"GO:0010572"(positive regulation of platelet activation)|go:"GO:0019369"(arachidonic acid metabolic process)|go:"GO:0019370"(leukotriene biosynthetic process)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0032308"(positive regulation of prostaglandin secretion)|go:"GO:0034478"(phosphatidylglycerol catabolic process)|go:"GO:0034638"(phosphatidylcholine catabolic process)|go:"GO:0036151"(phosphatidylcholine acyl-chain remodeling)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043032"(positive regulation of macrophage activation)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046475"(glycerophospholipid catabolic process)|go:"GO:0047498"(calcium-dependent phospholipase A2 activity)|go:"GO:0047499"(calcium-independent phospholipase A2 activity)|go:"GO:0050482"(arachidonic acid secretion)|go:"GO:0070273"(phosphatidylinositol-4-phosphate binding)|go:"GO:0071236"(cellular response to antibiotic)|go:"GO:0102545"(phosphatidyl phospholipase B activity)|go:"GO:0006690"(icosanoid metabolic process)|refseq:NP_001298122.1|refseq:XP_011507944.1|dip:DIP-40991N psi-mi:"MI:0465"(dip) crc64:BBA89770528FA9E9 crc64:EE71CA0EBE617856 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/05 2017/08/10 rogid:ZAfDrF1Nb8RnQqg0T50TaEJ3Xp09606 rogid:D/yM7EFWP6xaMQ//7wutJS5D3jw9606 rigid:hyS8crxOoqYmdXMK7UtT4nYgYwk false - sufficient binding region:1-121|sufficient binding region:1-129 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P28676 uniprotkb:P30626-1 intact:EBI-947242|uniprotkb:Q53TB5|uniprotkb:Q59EP3|uniprotkb:B2R5X3|ensembl:ENSP00000394842 intact:EBI-10816740|ensembl:ENSP00000265729 psi-mi:gran_human(display_long)|uniprotkb:GCA(gene name)|psi-mi:GCA(display_short)|uniprotkb:GCL(gene name synonym) psi-mi:p30626-1(display_long)|uniprotkb:22 kDa protein(gene name synonym)|uniprotkb:CP-22(gene name synonym)|uniprotkb:V19(gene name synonym)|uniprotkb:SRI(gene name)|psi-mi:SRI(display_short) psi-mi:"MI:0018"(two hybrid) DeGrado-Warren et al. (2008) pubmed:18330356|imex:IM-8752 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15691677|dip:DIP-70398E|imex:IM-8752-180 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_036330.1|dip:DIP-41437N|ensembl:ENSG00000115271(gene)|ensembl:ENST00000437150(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0061025"(membrane fusion)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|rcsb pdb:1F4O|rcsb pdb:1F4Q|rcsb pdb:1K94|rcsb pdb:1K95|reactome:R-HSA-6798695 intact:EBI-750459(isoform-parent)|ensembl:ENSG00000075142(gene)|ensembl:ENST00000265729(transcript) psi-mi:"MI:0465"(dip) crc64:88CA4DDF835AFFE4 - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/05 2017/08/10 rogid:I1zdQPwDUFrBGazaVREgC7nqxok9606 rogid:upE31IMimaotkgnYa7HYr7EYAxc9606 rigid:P3biU8Zjfa5ii/gfjl2Oa0CvL2Q false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P61968 uniprotkb:O43679-1 intact:EBI-2798728|uniprotkb:O00158|uniprotkb:O88894|uniprotkb:D3DT23|ensembl:ENSP00000359573|ensembl:ENSP00000359575 intact:EBI-15691011|ensembl:ENSP00000306772 psi-mi:lmo4_human(display_long)|uniprotkb:Breast tumor autoantigen(gene name synonym)|uniprotkb:LIM domain only protein 4(gene name synonym)|uniprotkb:LMO4(gene name)|psi-mi:LMO4(display_short) psi-mi:o43679-1(display_long)|uniprotkb:LDB2(gene name)|psi-mi:LDB2(display_short)|uniprotkb:CLIM1(gene name synonym)|uniprotkb:Carboxyl-terminal LIM domain-binding protein 1(gene name synonym)|uniprotkb:LIM domain-binding factor CLIM1(gene name synonym)|uniprotkb:CLIM1a(isoform synonym)|uniprotkb:a(isoform synonym) psi-mi:"MI:0018"(two hybrid) DeGrado-Warren et al. (2008) pubmed:18330356|imex:IM-8752 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15691709|dip:DIP-145131E|imex:IM-8752-100 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006760.1|refseq:XP_005271348.1|ensembl:ENSG00000143013(gene)|ensembl:ENST00000370542(transcript)|ensembl:ENST00000370544(transcript)|go:"GO:0001843"(neural tube closure)|go:"GO:0003281"(ventricular septum development)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0008134"(transcription factor binding)|go:"GO:0021514"(ventral spinal cord interneuron differentiation)|go:"GO:0021522"(spinal cord motor neuron differentiation)|go:"GO:0021527"(spinal cord association neuron differentiation)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031252"(cell leading edge)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0042659"(regulation of cell fate specification)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048538"(thymus development)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|interpro:IPR001781(Zinc finger, LIM-type)|mint:P61968|go:"GO:0050865"(regulation of cell activation)|rcsb pdb:2L4Z|dip:DIP-41414N intact:EBI-2865580(isoform-parent)|ensembl:ENSG00000169744(gene)|ensembl:ENST00000304523(transcript) psi-mi:"MI:0465"(dip) crc64:C8AC295144AD7787 - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/05 2017/08/10 rogid:A6F+R5tMkoNqN0nAuwTjOoVnjQE9606 rogid:3p/spcR1ariBlpLJczJxP5Mfi9w9606 rigid:pqhqoZe+3OzbDWAjQ/vzZOcb8mI false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q99598 uniprotkb:O43679-1 intact:EBI-742638|intact:EBI-1050136|uniprotkb:B1APC6|refseq:NP_005990|dip:DIP-29463N intact:EBI-15691011|ensembl:ENSP00000306772 psi-mi:tsnax_human(display_long)|uniprotkb:Translin-associated factor X(gene name synonym)|uniprotkb:TSNAX(gene name)|psi-mi:TSNAX(display_short)|uniprotkb:TRAX(gene name synonym) psi-mi:o43679-1(display_long)|uniprotkb:LDB2(gene name)|psi-mi:LDB2(display_short)|uniprotkb:CLIM1(gene name synonym)|uniprotkb:Carboxyl-terminal LIM domain-binding protein 1(gene name synonym)|uniprotkb:LIM domain-binding factor CLIM1(gene name synonym)|uniprotkb:CLIM1a(isoform synonym)|uniprotkb:a(isoform synonym) psi-mi:"MI:0018"(two hybrid) DeGrado-Warren et al. (2008) pubmed:18330356|imex:IM-8752 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15691693|dip:DIP-201378E|imex:IM-8752-140 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005634"(nucleus)|go:"GO:0008565"(obsolete protein transporter activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0007275"(multicellular organism development)|go:"GO:0007283"(spermatogenesis)|refseq:NP_005990.1|interpro:IPR002848(Translin)|interpro:IPR016068(Translin, N-terminal)|rcsb pdb:3PJA|rcsb pdb:3QB5|ensembl:ENST00000366639|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0031047"(gene silencing by RNA)|reactome:R-HSA-426486|go:"GO:0030422"(production of siRNA involved in RNA interference)|interpro:IPR036081|go:"GO:0003677"(DNA binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0046872"(metal ion binding)|go:"GO:0005829"(cytosol)|ensembl:ENSG00000116918|ensembl:ENSP00000355599|go:"GO:0005654"(nucleoplasm)|go:"GO:0003723"(RNA binding)|dip:DIP-29463N|mint:MINT-1347706|go:"GO:0044822"|interpro:IPR016069(Translin, C-terminal)|go:"GO:0031687"(A2A adenosine receptor binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0004521"(endoribonuclease activity)|go:"GO:0003697"(single-stranded DNA binding) intact:EBI-2865580(isoform-parent)|ensembl:ENSG00000169744(gene)|ensembl:ENST00000304523(transcript) psi-mi:"MI:0465"(dip) crc64:D38B0DD96B50C0B9|no-uniprot-update:|caution:"The protein could not be merged with EBI-12908040 because of some conflicts with the protein sequence (features which cannot be shifted)." - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/05 2017/08/10 rogid:TaNIxjLHGusdq32WbdJ21DG9yBQ9606 rogid:3p/spcR1ariBlpLJczJxP5Mfi9w9606 rigid:ePz0nXyMGmGd/XPJs5yTmkAcjvA false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O15212 uniprotkb:Q96EK4 intact:EBI-356973|ensembl:ENSP00000363734|ensembl:ENSP00000363735|ensembl:ENSP00000363738|ensembl:ENSP00000372694|ensembl:ENSP00000378563|ensembl:ENSP00000382314|ensembl:ENSP00000382316|ensembl:ENSP00000395462|ensembl:ENSP00000398171|ensembl:ENSP00000400152|ensembl:ENSP00000402212|ensembl:ENSP00000402553|ensembl:ENSP00000403771|ensembl:ENSP00000404773|ensembl:ENSP00000412319|ensembl:ENSP00000415678|ensembl:ENSP00000447540|ensembl:ENSP00000448607|ensembl:ENSP00000448784|ensembl:ENSP00000449925 intact:EBI-1790529|uniprotkb:O94795|uniprotkb:A8K002|uniprotkb:A4UCT5|ensembl:ENSP00000304689 psi-mi:pfd6_human(display_long)|uniprotkb:PFDN6(gene name)|psi-mi:PFDN6(display_short)|uniprotkb:HKE2(gene name synonym)|uniprotkb:PFD6(gene name synonym)|uniprotkb:Protein Ke2(gene name synonym) psi-mi:tha11_human(display_long)|uniprotkb:THAP11(gene name)|psi-mi:THAP11(display_short)|uniprotkb:HRIHFB2206(orf name) psi-mi:"MI:0018"(two hybrid) DeGrado-Warren et al. (2008) pubmed:18330356|imex:IM-8752 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15691725|dip:DIP-201385E|imex:IM-8752-80 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001172110.1|refseq:NP_055075.1|refseq:NP_001252524.1|refseq:NP_001252525.1|dip:DIP-50304N|ensembl:ENSG00000204220(gene)|ensembl:ENSG00000206283(gene)|ensembl:ENSG00000224782(gene)|ensembl:ENSG00000235692(gene)|ensembl:ENSG00000237335(gene)|ensembl:ENST00000374606(transcript)|ensembl:ENST00000374607(transcript)|ensembl:ENST00000374610(transcript)|ensembl:ENST00000383207(transcript)|ensembl:ENST00000395131(transcript)|ensembl:ENST00000399383(transcript)|ensembl:ENST00000399385(transcript)|ensembl:ENST00000412289(transcript)|ensembl:ENST00000425878(transcript)|ensembl:ENST00000431830(transcript)|ensembl:ENST00000432391(transcript)|ensembl:ENST00000442285(transcript)|ensembl:ENST00000445559(transcript)|ensembl:ENST00000448594(transcript)|ensembl:ENST00000451970(transcript)|ensembl:ENST00000452658(transcript)|ensembl:ENST00000547641(transcript)|ensembl:ENST00000547952(transcript)|ensembl:ENST00000548040(transcript)|ensembl:ENST00000552711(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006457"(protein folding)|go:"GO:0016272"(prefoldin complex)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:1905907"(negative regulation of amyloid fibril formation)|interpro:IPR002777(Prefoldin beta-like)|interpro:IPR009053(Prefoldin)|mint:O15212|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|reactome:R-HSA-389957 refseq:NP_065190.2|dip:DIP-46732N|ensembl:ENSP00000304689|ensembl:ENSG00000168286(gene)|ensembl:ENST00000303596(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|interpro:IPR006612(Zinc finger, C2CH-type)|rcsb pdb:2LAU|rcsb pdb:5AJS psi-mi:"MI:0465"(dip) crc64:8F138EAAE512A312 crc64:25235D20CB54D8C2 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/05 2017/08/10 rogid:t7Z68vuvmprxLIGDh4JhqCGvX+A9606 rogid:qzl6RN2xlTuDBruwyKLyDTNRCKE9606 rigid:scsp3qYOFCDfy+h5LV2dJicd7ug false - sufficient binding region:100-301|sufficient binding region:196-314|sufficient binding region:230-314 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification)