#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P50456 uniprotkb:P50456 intact:EBI-1116104|uniprotkb:P77593|ensemblbacteria:AAC74666|ensemblbacteria:BAA15318 intact:EBI-1116104|uniprotkb:P77593|ensemblbacteria:AAC74666|ensemblbacteria:BAA15318 psi-mi:mlc_ecoli(display_long)|uniprotkb:Making large colonies protein(gene name synonym)|uniprotkb:mlc(gene name)|psi-mi:mlc(display_short)|uniprotkb:b1594(locus name)|uniprotkb:JW1586(locus name) psi-mi:mlc_ecoli(display_long)|uniprotkb:Making large colonies protein(gene name synonym)|uniprotkb:mlc(gene name)|psi-mi:mlc(display_short)|uniprotkb:b1594(locus name)|uniprotkb:JW1586(locus name) psi-mi:"MI:0071"(molecular sieving) Nam et al. (2008) pubmed:18319344|doi:10.1073/pnas.0709295105|imex:IM-9182 taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15689866|imex:IM-9182-3|dip:DIP-45088E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_000225262.1|ensemblbacteria:AAC74666(transcript)|ensemblbacteria:b1594(gene)|ensemblbacteria:BAA15318(gene)|ensemblbacteria:BAA15318(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR000600(ROK)|interpro:IPR036388|interpro:IPR036390|interpro:IPR043129|rcsb pdb:1Z6R|rcsb pdb:3BP8|refseq:NP_416111.1|dip:DIP-10219N refseq:WP_000225262.1|ensemblbacteria:AAC74666(transcript)|ensemblbacteria:b1594(gene)|ensemblbacteria:BAA15318(gene)|ensemblbacteria:BAA15318(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR000600(ROK)|interpro:IPR036388|interpro:IPR036390|interpro:IPR043129|rcsb pdb:1Z6R|rcsb pdb:3BP8|refseq:NP_416111.1|dip:DIP-10219N psi-mi:"MI:0465"(dip) crc64:423608797FC980CB crc64:423608797FC980CB full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/05 2017/08/10 rogid:obadBxlWheuka75rBPGOUvKX/iw83333 rogid:obadBxlWheuka75rBPGOUvKX/iw83333 rigid:zX7mvj1tKhKE7wyunwYfk2fPs6M false - - - 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) intact:EBI-15689882 uniprotkb:P50456 dip:DIP-29834N intact:EBI-1116104|uniprotkb:P77593|ensemblbacteria:AAC74666|ensemblbacteria:BAA15318 psi-mi:grx2eiib(display_short)|psi-mi:EBI-15689882(display_long) psi-mi:mlc_ecoli(display_long)|uniprotkb:Making large colonies protein(gene name synonym)|uniprotkb:mlc(gene name)|psi-mi:mlc(display_short)|uniprotkb:b1594(locus name)|uniprotkb:JW1586(locus name) psi-mi:"MI:0413"(electrophoretic mobility shift assay) Nam et al. (2008) pubmed:18319344|doi:10.1073/pnas.0709295105|imex:IM-9182 taxid:562(ecolx)|taxid:562(Escherichia coli) taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15689885|imex:IM-9182-4|dip:DIP-59318E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - refseq:WP_000225262.1|ensemblbacteria:AAC74666(transcript)|ensemblbacteria:b1594(gene)|ensemblbacteria:BAA15318(gene)|ensemblbacteria:BAA15318(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR000600(ROK)|interpro:IPR036388|interpro:IPR036390|interpro:IPR043129|rcsb pdb:1Z6R|rcsb pdb:3BP8|refseq:NP_416111.1|dip:DIP-10219N psi-mi:"MI:0465"(dip) - crc64:423608797FC980CB full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/05 2017/08/10 rogid:R2H6eYqPvdLrhEiEVVSLICpTNfk562 rogid:obadBxlWheuka75rBPGOUvKX/iw83333 rigid:7YNYrebYYmUyq7XRgvMau2ysh0g false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P69786 uniprotkb:P50456 intact:EBI-903497|uniprotkb:P05053|ensemblbacteria:AAC74185|ensemblbacteria:BAA35908 intact:EBI-1116104|uniprotkb:P77593|ensemblbacteria:AAC74666|ensemblbacteria:BAA15318 psi-mi:ptgcb_ecoli(display_long)|uniprotkb:ptsG(gene name)|psi-mi:ptsG(display_short)|uniprotkb:glcA(gene name synonym)|uniprotkb:umg(gene name synonym)|uniprotkb:b1101(locus name)|uniprotkb:EIICB-Glc(gene name synonym)|uniprotkb:JW1087(locus name) psi-mi:mlc_ecoli(display_long)|uniprotkb:Making large colonies protein(gene name synonym)|uniprotkb:mlc(gene name)|psi-mi:mlc(display_short)|uniprotkb:b1594(locus name)|uniprotkb:JW1586(locus name) psi-mi:"MI:0114"(x-ray crystallography) Nam et al. (2008) pubmed:18319344|doi:10.1073/pnas.0709295105|imex:IM-9182 taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15689903|imex:IM-9182-1|dip:DIP-59317E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_000475719.1|refseq:NP_415619.1|dip:DIP-29833N|ensemblbacteria:AAC74185(transcript)|ensemblbacteria:b1101(gene)|ensemblbacteria:BAA35908(gene)|ensemblbacteria:BAA35908(transcript)|go:"GO:0005355"(glucose transmembrane transporter activity)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0008982"("protein-N(PI)-phosphohistidine-sugar phosphotransferase activity")|go:"GO:0009401"(phosphoenolpyruvate-dependent sugar phosphotransferase system)|go:"GO:0016301"(kinase activity)|go:"GO:0090563"(protein-phosphocysteine-sugar phosphotransferase activity)|go:"GO:0090564"(protein-phosphocysteine-glucose phosphotransferase system transporter activity)|go:"GO:1904659"(glucose transmembrane transport)|interpro:IPR001996(Phosphotransferase system, EIIB)|interpro:IPR003352(Phosphotransferase system, EIIC)|interpro:IPR004719(Phosphotransferase system, maltose and glucose-specific IIC component)|interpro:IPR011299(Phosphotransferase system, glucose-specific IIBC component)|interpro:IPR013013(Phosphotransferase system, EIIC component, type 1)|interpro:IPR018113|interpro:IPR036878|rcsb pdb:1IBA|rcsb pdb:1O2F|rcsb pdb:3BP3|rcsb pdb:3BP8 refseq:WP_000225262.1|ensemblbacteria:AAC74666(transcript)|ensemblbacteria:b1594(gene)|ensemblbacteria:BAA15318(gene)|ensemblbacteria:BAA15318(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR000600(ROK)|interpro:IPR036388|interpro:IPR036390|interpro:IPR043129|rcsb pdb:1Z6R|rcsb pdb:3BP8|refseq:NP_416111.1|dip:DIP-10219N psi-mi:"MI:0465"(dip) crc64:D97A80FD64B74F73 crc64:423608797FC980CB full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/05 2017/08/10 rogid:aXzx4vGY3r3eNN8heYDCCWCUhxI83333 rogid:obadBxlWheuka75rBPGOUvKX/iw83333 rigid:hD0V4ZouGKlePzLhzwsZ4+didbM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P69786 uniprotkb:P50456 intact:EBI-903497|uniprotkb:P05053|ensemblbacteria:AAC74185|ensemblbacteria:BAA35908 intact:EBI-1116104|uniprotkb:P77593|ensemblbacteria:AAC74666|ensemblbacteria:BAA15318 psi-mi:ptgcb_ecoli(display_long)|uniprotkb:ptsG(gene name)|psi-mi:ptsG(display_short)|uniprotkb:glcA(gene name synonym)|uniprotkb:umg(gene name synonym)|uniprotkb:b1101(locus name)|uniprotkb:EIICB-Glc(gene name synonym)|uniprotkb:JW1087(locus name) psi-mi:mlc_ecoli(display_long)|uniprotkb:Making large colonies protein(gene name synonym)|uniprotkb:mlc(gene name)|psi-mi:mlc(display_short)|uniprotkb:b1594(locus name)|uniprotkb:JW1586(locus name) psi-mi:"MI:0107"(surface plasmon resonance) Nam et al. (2008) pubmed:18319344|doi:10.1073/pnas.0709295105|imex:IM-9182 taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15689920|imex:IM-9182-2|dip:DIP-59317E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_000475719.1|refseq:NP_415619.1|dip:DIP-29833N|ensemblbacteria:AAC74185(transcript)|ensemblbacteria:b1101(gene)|ensemblbacteria:BAA35908(gene)|ensemblbacteria:BAA35908(transcript)|go:"GO:0005355"(glucose transmembrane transporter activity)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0008982"("protein-N(PI)-phosphohistidine-sugar phosphotransferase activity")|go:"GO:0009401"(phosphoenolpyruvate-dependent sugar phosphotransferase system)|go:"GO:0016301"(kinase activity)|go:"GO:0090563"(protein-phosphocysteine-sugar phosphotransferase activity)|go:"GO:0090564"(protein-phosphocysteine-glucose phosphotransferase system transporter activity)|go:"GO:1904659"(glucose transmembrane transport)|interpro:IPR001996(Phosphotransferase system, EIIB)|interpro:IPR003352(Phosphotransferase system, EIIC)|interpro:IPR004719(Phosphotransferase system, maltose and glucose-specific IIC component)|interpro:IPR011299(Phosphotransferase system, glucose-specific IIBC component)|interpro:IPR013013(Phosphotransferase system, EIIC component, type 1)|interpro:IPR018113|interpro:IPR036878|rcsb pdb:1IBA|rcsb pdb:1O2F|rcsb pdb:3BP3|rcsb pdb:3BP8 refseq:WP_000225262.1|ensemblbacteria:AAC74666(transcript)|ensemblbacteria:b1594(gene)|ensemblbacteria:BAA15318(gene)|ensemblbacteria:BAA15318(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR000600(ROK)|interpro:IPR036388|interpro:IPR036390|interpro:IPR043129|rcsb pdb:1Z6R|rcsb pdb:3BP8|refseq:NP_416111.1|dip:DIP-10219N psi-mi:"MI:0465"(dip) crc64:D97A80FD64B74F73 crc64:423608797FC980CB full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/05 2017/08/10 rogid:aXzx4vGY3r3eNN8heYDCCWCUhxI83333 rogid:obadBxlWheuka75rBPGOUvKX/iw83333 rigid:hD0V4ZouGKlePzLhzwsZ4+didbM false mutation disrupting interaction:449-449|mutation disrupting interaction:456-456|mutation decreasing interaction:451-451 - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)