#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q14527 uniprotkb:Q9NS91 intact:EBI-1045161|uniprotkb:Q14536|uniprotkb:Q16051|uniprotkb:Q7KYJ6|uniprotkb:Q86YA5|uniprotkb:Q92652|uniprotkb:Q96KM9|uniprotkb:D3DNH3|ensembl:ENSP00000308944|ensembl:ENSP00000376644|ensembl:ENSP00000420429 intact:EBI-2339393|uniprotkb:Q9NRT6|uniprotkb:Q58F55|ensembl:ENSP00000264926 psi-mi:hltf_human(display_long)|uniprotkb:SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3(gene name synonym)|uniprotkb:Sucrose nonfermenting protein 2-like 3(gene name synonym)|uniprotkb:DNA-binding protein/plasminogen activator inhibitor 1 regulator(gene name synonym)|uniprotkb:HIP116(gene name synonym)|uniprotkb:RING finger protein 80(gene name synonym)|uniprotkb:HLTF(gene name)|psi-mi:HLTF(display_short)|uniprotkb:HIP116A(gene name synonym)|uniprotkb:RNF80(gene name synonym)|uniprotkb:SNF2L3(gene name synonym)|uniprotkb:ZBU1(gene name synonym)|uniprotkb:SMARCA3(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase HLTF(gene name synonym) psi-mi:rad18_human(display_long)|uniprotkb:RAD18(gene name)|psi-mi:RAD18(display_short)|uniprotkb:RNF73(gene name synonym)|uniprotkb:Postreplication repair protein RAD18(gene name synonym)|uniprotkb:RING finger protein 73(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RAD18(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Unk et al. (2008) pubmed:18316726|doi:10.1073/pnas.0800563105|imex:IM-9180 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-15689517|imex:IM-9180-2|dip:DIP-59314E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001305863.1|refseq:NP_001305864.1|refseq:NP_003062.2|refseq:NP_620636.1|refseq:XP_016862568.1|dip:DIP-29828N|ensembl:ENSG00000071794(gene)|ensembl:ENST00000310053(transcript)|ensembl:ENST00000392912(transcript)|ensembl:ENST00000494055(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016020"(membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016818"(hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070615"|interpro:IPR000330(SNF2-related)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014905(HIRAN)|interpro:IPR017907|interpro:IPR027417|interpro:IPR038718|mint:Q14527|rcsb pdb:2MZN|rcsb pdb:4HRE|rcsb pdb:4HRH|rcsb pdb:4S0N|rcsb pdb:4XZF|rcsb pdb:4XZG|rcsb pdb:5BNH|rcsb pdb:5K5F|rcsb pdb:6KCS|reactome:R-HSA-8866654 refseq:NP_064550.3|ensembl:ENSP00000264926|dip:DIP-29831N|ensembl:ENSG00000070950(gene)|ensembl:ENST00000264926(transcript)|go:"GO:0000403"(Y-form DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005657"(replication fork)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0006281"(DNA repair)|go:"GO:0006301"(postreplication repair)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016604"(nuclear body)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042405"(nuclear inclusion body)|go:"GO:0042802"(identical protein binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0051984"(positive regulation of chromosome segregation)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0097505"(Rad6-Rad18 complex)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003034(DNA-binding SAP)|interpro:IPR006642(Zinc finger, Rad18-type putative)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR036361|interpro:IPR039577|mint:Q9NS91|rcsb pdb:2MRE|rcsb pdb:2MRF|rcsb pdb:2Y43|rcsb pdb:2YBF|rcsb pdb:5VF0|reactome:R-HSA-110314|reactome:R-HSA-8866654|go:"GO:0060548"(negative regulation of cell death) psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/05 2017/08/10 rogid:ozxGwYPSrDJ+Fg3F64VfE0Bc0wM9606 rogid:/HmKCLqG1BxzmIWCgVpOw/gzJc49606 rigid:nmyj9G1B1l9LpwAPRker9Fs6/oo false flag tag:n-n ha tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q14527 uniprotkb:Q15819 intact:EBI-1045161|uniprotkb:Q14536|uniprotkb:Q16051|uniprotkb:Q7KYJ6|uniprotkb:Q86YA5|uniprotkb:Q92652|uniprotkb:Q96KM9|uniprotkb:D3DNH3|ensembl:ENSP00000308944|ensembl:ENSP00000376644|ensembl:ENSP00000420429 intact:EBI-714329|ensembl:ENSP00000428209 psi-mi:hltf_human(display_long)|uniprotkb:SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3(gene name synonym)|uniprotkb:Sucrose nonfermenting protein 2-like 3(gene name synonym)|uniprotkb:DNA-binding protein/plasminogen activator inhibitor 1 regulator(gene name synonym)|uniprotkb:HIP116(gene name synonym)|uniprotkb:RING finger protein 80(gene name synonym)|uniprotkb:HLTF(gene name)|psi-mi:HLTF(display_short)|uniprotkb:HIP116A(gene name synonym)|uniprotkb:RNF80(gene name synonym)|uniprotkb:SNF2L3(gene name synonym)|uniprotkb:ZBU1(gene name synonym)|uniprotkb:SMARCA3(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase HLTF(gene name synonym) psi-mi:ub2v2_human(display_long)|uniprotkb:MMS2 homolog(gene name synonym)|uniprotkb:Enterocyte differentiation-associated factor 1(gene name synonym)|uniprotkb:Enterocyte differentiation-promoting factor 1(gene name synonym)|uniprotkb:Vitamin D3-inducible protein(gene name synonym)|uniprotkb:DDVit 1(gene name synonym)|uniprotkb:UBE2V2(gene name)|psi-mi:UBE2V2(display_short)|uniprotkb:MMS2(gene name synonym)|uniprotkb:UEV2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Unk et al. (2008) pubmed:18316726|doi:10.1073/pnas.0800563105|imex:IM-9180 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-15689517|imex:IM-9180-2|dip:DIP-59314E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001305863.1|refseq:NP_001305864.1|refseq:NP_003062.2|refseq:NP_620636.1|refseq:XP_016862568.1|dip:DIP-29828N|ensembl:ENSG00000071794(gene)|ensembl:ENST00000310053(transcript)|ensembl:ENST00000392912(transcript)|ensembl:ENST00000494055(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016020"(membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016818"(hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070615"|interpro:IPR000330(SNF2-related)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014905(HIRAN)|interpro:IPR017907|interpro:IPR027417|interpro:IPR038718|mint:Q14527|rcsb pdb:2MZN|rcsb pdb:4HRE|rcsb pdb:4HRH|rcsb pdb:4S0N|rcsb pdb:4XZF|rcsb pdb:4XZG|rcsb pdb:5BNH|rcsb pdb:5K5F|rcsb pdb:6KCS|reactome:R-HSA-8866654 rcsb pdb:5AIT|refseq:NP_003341.1|ensembl:ENSG00000169139(gene)|ensembl:ENST00000523111(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000729"(DNA double-strand break processing)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006282"(regulation of DNA repair)|go:"GO:0006301"(postreplication repair)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031372"(UBC13-MMS2 complex)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0042275"(error-free postreplication DNA repair)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0051965"(positive regulation of synapse assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070534"(protein K63-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|mint:Q15819|rcsb pdb:1J74|rcsb pdb:1J7D|rcsb pdb:1ZGU|rcsb pdb:3VON|rcsb pdb:4NR3|rcsb pdb:4NRG|rcsb pdb:4NRI|rcsb pdb:4ONL|rcsb pdb:4ONM|rcsb pdb:4ONN|rcsb pdb:4ORH|rcsb pdb:7BBF|reactome:R-HSA-5693565|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-5696395|reactome:R-HSA-69473|reactome:R-HSA-8866654|reactome:R-HSA-983168|rcsb pdb:7BBD|dip:DIP-29830N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/05 2017/08/10 rogid:ozxGwYPSrDJ+Fg3F64VfE0Bc0wM9606 rogid:i4SsftsLfkr72ufUq4QZn571iDQ9606 rigid:nmyj9G1B1l9LpwAPRker9Fs6/oo false flag tag:n-n ha tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q14527 uniprotkb:P61088 intact:EBI-1045161|uniprotkb:Q14536|uniprotkb:Q16051|uniprotkb:Q7KYJ6|uniprotkb:Q86YA5|uniprotkb:Q92652|uniprotkb:Q96KM9|uniprotkb:D3DNH3|ensembl:ENSP00000308944|ensembl:ENSP00000376644|ensembl:ENSP00000420429 intact:EBI-1052908|uniprotkb:Q16781|uniprotkb:Q53Y81|ensembl:ENSP00000316176 psi-mi:hltf_human(display_long)|uniprotkb:SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3(gene name synonym)|uniprotkb:Sucrose nonfermenting protein 2-like 3(gene name synonym)|uniprotkb:DNA-binding protein/plasminogen activator inhibitor 1 regulator(gene name synonym)|uniprotkb:HIP116(gene name synonym)|uniprotkb:RING finger protein 80(gene name synonym)|uniprotkb:HLTF(gene name)|psi-mi:HLTF(display_short)|uniprotkb:HIP116A(gene name synonym)|uniprotkb:RNF80(gene name synonym)|uniprotkb:SNF2L3(gene name synonym)|uniprotkb:ZBU1(gene name synonym)|uniprotkb:SMARCA3(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase HLTF(gene name synonym) psi-mi:ube2n_human(display_long)|uniprotkb:Ubiquitin-protein ligase N(gene name synonym)|uniprotkb:Ubiquitin carrier protein N(gene name synonym)|uniprotkb:Ubc13(gene name synonym)|uniprotkb:Bendless-like ubiquitin-conjugating enzyme(gene name synonym)|uniprotkb:UBE2N(gene name)|psi-mi:UBE2N(display_short)|uniprotkb:BLU(gene name synonym)|uniprotkb:UbcH13(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme N(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Unk et al. (2008) pubmed:18316726|doi:10.1073/pnas.0800563105|imex:IM-9180 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-15689517|imex:IM-9180-2|dip:DIP-59314E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001305863.1|refseq:NP_001305864.1|refseq:NP_003062.2|refseq:NP_620636.1|refseq:XP_016862568.1|dip:DIP-29828N|ensembl:ENSG00000071794(gene)|ensembl:ENST00000310053(transcript)|ensembl:ENST00000392912(transcript)|ensembl:ENST00000494055(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016020"(membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016818"(hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070615"|interpro:IPR000330(SNF2-related)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014905(HIRAN)|interpro:IPR017907|interpro:IPR027417|interpro:IPR038718|mint:Q14527|rcsb pdb:2MZN|rcsb pdb:4HRE|rcsb pdb:4HRH|rcsb pdb:4S0N|rcsb pdb:4XZF|rcsb pdb:4XZG|rcsb pdb:5BNH|rcsb pdb:5K5F|rcsb pdb:6KCS|reactome:R-HSA-8866654 refseq:NP_003339.1|dip:DIP-29829N|ensembl:ENSG00000177889(gene)|ensembl:ENST00000318066(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000729"(DNA double-strand break processing)|go:"GO:0001650"(fibrillar center)|go:"GO:0003723"(RNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006282"(regulation of DNA repair)|go:"GO:0006301"(postreplication repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0031058"(positive regulation of histone modification)|go:"GO:0031372"(UBC13-MMS2 complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033182"(regulation of histone ubiquitination)|go:"GO:0035370"(UBC13-UEV1A complex)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051443"(positive regulation of ubiquitin-protein transferase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070534"(protein K63-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:1J7D|rcsb pdb:2C2V|rcsb pdb:3HCT|rcsb pdb:3HCU|rcsb pdb:3VON|rcsb pdb:3W31|rcsb pdb:4DHI|rcsb pdb:4DHJ|rcsb pdb:4DHZ|rcsb pdb:4IP3|rcsb pdb:4NR3|rcsb pdb:4NRG|rcsb pdb:4NRI|rcsb pdb:4ONL|rcsb pdb:4ONM|rcsb pdb:4ONN|rcsb pdb:4ORH|rcsb pdb:4TKP|rcsb pdb:4WHV|rcsb pdb:5AIT|rcsb pdb:5AIU|rcsb pdb:5EYA|rcsb pdb:5H7S|rcsb pdb:5VNZ|rcsb pdb:5VO0|rcsb pdb:5YWR|rcsb pdb:6D6I|rcsb pdb:6JKY|rcsb pdb:6KFP|rcsb pdb:6KG6|rcsb pdb:6KL4|rcsb pdb:6LP2|rcsb pdb:6P5B|rcsb pdb:6S53|reactome:R-HSA-168927|reactome:R-HSA-202424|reactome:R-HSA-2871837|reactome:R-HSA-445989|reactome:R-HSA-450302|reactome:R-HSA-450321|reactome:R-HSA-5607764|reactome:R-HSA-5693565|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-5696395|reactome:R-HSA-69473|reactome:R-HSA-8866654|reactome:R-HSA-9020702|reactome:R-HSA-937039|reactome:R-HSA-937041|reactome:R-HSA-9646399|reactome:R-HSA-975110|reactome:R-HSA-975144|reactome:R-HSA-983168|rcsb pdb:6ULH|rcsb pdb:6UMP|rcsb pdb:6UMS|rcsb pdb:7BBD|rcsb pdb:7BBF|rcsb pdb:7BXG|reactome:R-HSA-1169408|reactome:R-HSA-168638 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/05 2017/08/10 rogid:ozxGwYPSrDJ+Fg3F64VfE0Bc0wM9606 rogid:dqdszHlq5FLPHC6UWX6uvkC6Yz89606 rigid:nmyj9G1B1l9LpwAPRker9Fs6/oo false flag tag:n-n ha tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q14527 uniprotkb:P12004 intact:EBI-1045161|uniprotkb:Q14536|uniprotkb:Q16051|uniprotkb:Q7KYJ6|uniprotkb:Q86YA5|uniprotkb:Q92652|uniprotkb:Q96KM9|uniprotkb:D3DNH3|ensembl:ENSP00000308944|ensembl:ENSP00000376644|ensembl:ENSP00000420429 intact:EBI-358311|uniprotkb:B2R897|uniprotkb:D3DW02|ensembl:ENSP00000368438|ensembl:ENSP00000368458 psi-mi:hltf_human(display_long)|uniprotkb:SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3(gene name synonym)|uniprotkb:Sucrose nonfermenting protein 2-like 3(gene name synonym)|uniprotkb:DNA-binding protein/plasminogen activator inhibitor 1 regulator(gene name synonym)|uniprotkb:HIP116(gene name synonym)|uniprotkb:RING finger protein 80(gene name synonym)|uniprotkb:HLTF(gene name)|psi-mi:HLTF(display_short)|uniprotkb:HIP116A(gene name synonym)|uniprotkb:RNF80(gene name synonym)|uniprotkb:SNF2L3(gene name synonym)|uniprotkb:ZBU1(gene name synonym)|uniprotkb:SMARCA3(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase HLTF(gene name synonym) psi-mi:pcna_human(display_long)|uniprotkb:PCNA(gene name)|psi-mi:PCNA(display_short)|uniprotkb:Cyclin(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Unk et al. (2008) pubmed:18316726|doi:10.1073/pnas.0800563105|imex:IM-9180 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-15689517|imex:IM-9180-2|dip:DIP-59314E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001305863.1|refseq:NP_001305864.1|refseq:NP_003062.2|refseq:NP_620636.1|refseq:XP_016862568.1|dip:DIP-29828N|ensembl:ENSG00000071794(gene)|ensembl:ENST00000310053(transcript)|ensembl:ENST00000392912(transcript)|ensembl:ENST00000494055(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016020"(membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016818"(hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070615"|interpro:IPR000330(SNF2-related)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014905(HIRAN)|interpro:IPR017907|interpro:IPR027417|interpro:IPR038718|mint:Q14527|rcsb pdb:2MZN|rcsb pdb:4HRE|rcsb pdb:4HRH|rcsb pdb:4S0N|rcsb pdb:4XZF|rcsb pdb:4XZG|rcsb pdb:5BNH|rcsb pdb:5K5F|rcsb pdb:6KCS|reactome:R-HSA-8866654 refseq:NP_002583.1|refseq:NP_872590.1|ensembl:ENSG00000132646(gene)|ensembl:ENST00000379143(transcript)|ensembl:ENST00000379160(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000307"(cyclin-dependent protein kinase holoenzyme complex)|go:"GO:0000701"(purine-specific mismatch base pair DNA N-glycosylase activity)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005652"(nuclear lamina)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005657"(replication fork)|go:"GO:0005813"(centrosome)|go:"GO:0006272"(leading strand elongation)|go:"GO:0006287"(base-excision repair, gap-filling)|go:"GO:0006298"(mismatch repair)|go:"GO:0007507"(heart development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016604"(nuclear body)|go:"GO:0019899"(enzyme binding)|go:"GO:0019985"(translesion synthesis)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030337"(DNA polymerase processivity factor activity)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0030894"(replisome)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031297"(replication fork processing)|go:"GO:0032077"(positive regulation of deoxyribonuclease activity)|go:"GO:0032139"(dinucleotide insertion or deletion binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0032405"(MutLalpha complex binding)|go:"GO:0034644"(cellular response to UV)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043596"(nuclear replication fork)|go:"GO:0043626"(PCNA complex)|go:"GO:0044849"(estrous cycle)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0046686"(response to cadmium ion)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070557"(PCNA-p21 complex)|go:"GO:0071466"(cellular response to xenobiotic stimulus)|go:"GO:0071548"(response to dexamethasone)|go:"GO:0097421"(liver regeneration)|go:"GO:1900264"(positive regulation of DNA-directed DNA polymerase activity)|go:"GO:1902065"(response to L-glutamate)|go:"GO:1902990"(mitotic telomere maintenance via semi-conservative replication)|interpro:IPR000730(Proliferating cell nuclear antigen, PCNA)|interpro:IPR022648|interpro:IPR022649|interpro:IPR022659|mint:P12004|rcsb pdb:1AXC|rcsb pdb:1U76|rcsb pdb:1U7B|rcsb pdb:1UL1|rcsb pdb:1VYJ|rcsb pdb:1VYM|rcsb pdb:1W60|rcsb pdb:2ZVK|rcsb pdb:2ZVL|rcsb pdb:2ZVM|rcsb pdb:3JA9|rcsb pdb:3P87|rcsb pdb:3TBL|rcsb pdb:3VKX|rcsb pdb:3WGW|rcsb pdb:4D2G|rcsb pdb:4RJF|rcsb pdb:4ZTD|rcsb pdb:5E0T|rcsb pdb:5E0U|rcsb pdb:5E0V|rcsb pdb:5IY4|rcsb pdb:5MAV|rcsb pdb:5MLO|rcsb pdb:5MLW|reactome:R-HSA-5651801|rcsb pdb:5MOM|rcsb pdb:5YCO|rcsb pdb:5YD8|rcsb pdb:6CBI|rcsb pdb:6EHT|rcsb pdb:6FCM|rcsb pdb:6FCN|rcsb pdb:6GIS|rcsb pdb:6GWS|rcsb pdb:6HVO|rcsb pdb:6K3A|rcsb pdb:6QC0|rcsb pdb:6QCG|rcsb pdb:6S1M|rcsb pdb:6S1N|rcsb pdb:6S1O|rcsb pdb:6TNY|rcsb pdb:6TNZ|rcsb pdb:6VVO|rcsb pdb:7EFA|rcsb pdb:7KQ0|rcsb pdb:7KQ1|reactome:R-HSA-110312|reactome:R-HSA-110314|reactome:R-HSA-110320|reactome:R-HSA-1362277|reactome:R-HSA-174411|reactome:R-HSA-174414|reactome:R-HSA-174417|reactome:R-HSA-174437|reactome:R-HSA-4615885|reactome:R-HSA-5358565|reactome:R-HSA-5358606|reactome:R-HSA-5656121|reactome:R-HSA-5656169|reactome:R-HSA-5685942|reactome:R-HSA-5696397|reactome:R-HSA-5696400|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6804114|reactome:R-HSA-69091|reactome:R-HSA-69166|reactome:R-HSA-69183|reactome:R-HSA-69205|reactome:R-HSA-8866654|reactome:R-HSA-5655862|dip:DIP-1098N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/05 2017/08/10 rogid:ozxGwYPSrDJ+Fg3F64VfE0Bc0wM9606 rogid:5JUv5dKFwQAAaXm5aEiwCXVoAOM9606 rigid:nmyj9G1B1l9LpwAPRker9Fs6/oo false flag tag:n-n ha tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q14527 uniprotkb:P61088 intact:EBI-1045161|uniprotkb:Q14536|uniprotkb:Q16051|uniprotkb:Q7KYJ6|uniprotkb:Q86YA5|uniprotkb:Q92652|uniprotkb:Q96KM9|uniprotkb:D3DNH3|ensembl:ENSP00000308944|ensembl:ENSP00000376644|ensembl:ENSP00000420429 intact:EBI-1052908|uniprotkb:Q16781|uniprotkb:Q53Y81|ensembl:ENSP00000316176 psi-mi:hltf_human(display_long)|uniprotkb:SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3(gene name synonym)|uniprotkb:Sucrose nonfermenting protein 2-like 3(gene name synonym)|uniprotkb:DNA-binding protein/plasminogen activator inhibitor 1 regulator(gene name synonym)|uniprotkb:HIP116(gene name synonym)|uniprotkb:RING finger protein 80(gene name synonym)|uniprotkb:HLTF(gene name)|psi-mi:HLTF(display_short)|uniprotkb:HIP116A(gene name synonym)|uniprotkb:RNF80(gene name synonym)|uniprotkb:SNF2L3(gene name synonym)|uniprotkb:ZBU1(gene name synonym)|uniprotkb:SMARCA3(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase HLTF(gene name synonym) psi-mi:ube2n_human(display_long)|uniprotkb:Ubiquitin-protein ligase N(gene name synonym)|uniprotkb:Ubiquitin carrier protein N(gene name synonym)|uniprotkb:Ubc13(gene name synonym)|uniprotkb:Bendless-like ubiquitin-conjugating enzyme(gene name synonym)|uniprotkb:UBE2N(gene name)|psi-mi:UBE2N(display_short)|uniprotkb:BLU(gene name synonym)|uniprotkb:UbcH13(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme N(gene name synonym) psi-mi:"MI:0096"(pull down) Unk et al. (2008) pubmed:18316726|doi:10.1073/pnas.0800563105|imex:IM-9180 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-15689547|imex:IM-9180-1|dip:DIP-59315E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001305863.1|refseq:NP_001305864.1|refseq:NP_003062.2|refseq:NP_620636.1|refseq:XP_016862568.1|dip:DIP-29828N|ensembl:ENSG00000071794(gene)|ensembl:ENST00000310053(transcript)|ensembl:ENST00000392912(transcript)|ensembl:ENST00000494055(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016020"(membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016818"(hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070615"|interpro:IPR000330(SNF2-related)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014905(HIRAN)|interpro:IPR017907|interpro:IPR027417|interpro:IPR038718|mint:Q14527|rcsb pdb:2MZN|rcsb pdb:4HRE|rcsb pdb:4HRH|rcsb pdb:4S0N|rcsb pdb:4XZF|rcsb pdb:4XZG|rcsb pdb:5BNH|rcsb pdb:5K5F|rcsb pdb:6KCS|reactome:R-HSA-8866654 refseq:NP_003339.1|dip:DIP-29829N|ensembl:ENSG00000177889(gene)|ensembl:ENST00000318066(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000729"(DNA double-strand break processing)|go:"GO:0001650"(fibrillar center)|go:"GO:0003723"(RNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006282"(regulation of DNA repair)|go:"GO:0006301"(postreplication repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0031058"(positive regulation of histone modification)|go:"GO:0031372"(UBC13-MMS2 complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033182"(regulation of histone ubiquitination)|go:"GO:0035370"(UBC13-UEV1A complex)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051443"(positive regulation of ubiquitin-protein transferase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070534"(protein K63-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:1J7D|rcsb pdb:2C2V|rcsb pdb:3HCT|rcsb pdb:3HCU|rcsb pdb:3VON|rcsb pdb:3W31|rcsb pdb:4DHI|rcsb pdb:4DHJ|rcsb pdb:4DHZ|rcsb pdb:4IP3|rcsb pdb:4NR3|rcsb pdb:4NRG|rcsb pdb:4NRI|rcsb pdb:4ONL|rcsb pdb:4ONM|rcsb pdb:4ONN|rcsb pdb:4ORH|rcsb pdb:4TKP|rcsb pdb:4WHV|rcsb pdb:5AIT|rcsb pdb:5AIU|rcsb pdb:5EYA|rcsb pdb:5H7S|rcsb pdb:5VNZ|rcsb pdb:5VO0|rcsb pdb:5YWR|rcsb pdb:6D6I|rcsb pdb:6JKY|rcsb pdb:6KFP|rcsb pdb:6KG6|rcsb pdb:6KL4|rcsb pdb:6LP2|rcsb pdb:6P5B|rcsb pdb:6S53|reactome:R-HSA-168927|reactome:R-HSA-202424|reactome:R-HSA-2871837|reactome:R-HSA-445989|reactome:R-HSA-450302|reactome:R-HSA-450321|reactome:R-HSA-5607764|reactome:R-HSA-5693565|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-5696395|reactome:R-HSA-69473|reactome:R-HSA-8866654|reactome:R-HSA-9020702|reactome:R-HSA-937039|reactome:R-HSA-937041|reactome:R-HSA-9646399|reactome:R-HSA-975110|reactome:R-HSA-975144|reactome:R-HSA-983168|rcsb pdb:6ULH|rcsb pdb:6UMP|rcsb pdb:6UMS|rcsb pdb:7BBD|rcsb pdb:7BBF|rcsb pdb:7BXG|reactome:R-HSA-1169408|reactome:R-HSA-168638 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/05 2017/08/10 rogid:ozxGwYPSrDJ+Fg3F64VfE0Bc0wM9606 rogid:dqdszHlq5FLPHC6UWX6uvkC6Yz89606 rigid:W3yJmjXouErRnmSmRtjS2IFmDH4 false glutathione s tranferase tag:n-n - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q14527 uniprotkb:Q15819 intact:EBI-1045161|uniprotkb:Q14536|uniprotkb:Q16051|uniprotkb:Q7KYJ6|uniprotkb:Q86YA5|uniprotkb:Q92652|uniprotkb:Q96KM9|uniprotkb:D3DNH3|ensembl:ENSP00000308944|ensembl:ENSP00000376644|ensembl:ENSP00000420429 intact:EBI-714329|ensembl:ENSP00000428209 psi-mi:hltf_human(display_long)|uniprotkb:SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3(gene name synonym)|uniprotkb:Sucrose nonfermenting protein 2-like 3(gene name synonym)|uniprotkb:DNA-binding protein/plasminogen activator inhibitor 1 regulator(gene name synonym)|uniprotkb:HIP116(gene name synonym)|uniprotkb:RING finger protein 80(gene name synonym)|uniprotkb:HLTF(gene name)|psi-mi:HLTF(display_short)|uniprotkb:HIP116A(gene name synonym)|uniprotkb:RNF80(gene name synonym)|uniprotkb:SNF2L3(gene name synonym)|uniprotkb:ZBU1(gene name synonym)|uniprotkb:SMARCA3(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase HLTF(gene name synonym) psi-mi:ub2v2_human(display_long)|uniprotkb:MMS2 homolog(gene name synonym)|uniprotkb:Enterocyte differentiation-associated factor 1(gene name synonym)|uniprotkb:Enterocyte differentiation-promoting factor 1(gene name synonym)|uniprotkb:Vitamin D3-inducible protein(gene name synonym)|uniprotkb:DDVit 1(gene name synonym)|uniprotkb:UBE2V2(gene name)|psi-mi:UBE2V2(display_short)|uniprotkb:MMS2(gene name synonym)|uniprotkb:UEV2(gene name synonym) psi-mi:"MI:0096"(pull down) Unk et al. (2008) pubmed:18316726|doi:10.1073/pnas.0800563105|imex:IM-9180 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-15689547|imex:IM-9180-1|dip:DIP-59315E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001305863.1|refseq:NP_001305864.1|refseq:NP_003062.2|refseq:NP_620636.1|refseq:XP_016862568.1|dip:DIP-29828N|ensembl:ENSG00000071794(gene)|ensembl:ENST00000310053(transcript)|ensembl:ENST00000392912(transcript)|ensembl:ENST00000494055(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016020"(membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016818"(hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070615"|interpro:IPR000330(SNF2-related)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014905(HIRAN)|interpro:IPR017907|interpro:IPR027417|interpro:IPR038718|mint:Q14527|rcsb pdb:2MZN|rcsb pdb:4HRE|rcsb pdb:4HRH|rcsb pdb:4S0N|rcsb pdb:4XZF|rcsb pdb:4XZG|rcsb pdb:5BNH|rcsb pdb:5K5F|rcsb pdb:6KCS|reactome:R-HSA-8866654 rcsb pdb:5AIT|refseq:NP_003341.1|ensembl:ENSG00000169139(gene)|ensembl:ENST00000523111(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000729"(DNA double-strand break processing)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006282"(regulation of DNA repair)|go:"GO:0006301"(postreplication repair)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031372"(UBC13-MMS2 complex)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0042275"(error-free postreplication DNA repair)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0051965"(positive regulation of synapse assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070534"(protein K63-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|mint:Q15819|rcsb pdb:1J74|rcsb pdb:1J7D|rcsb pdb:1ZGU|rcsb pdb:3VON|rcsb pdb:4NR3|rcsb pdb:4NRG|rcsb pdb:4NRI|rcsb pdb:4ONL|rcsb pdb:4ONM|rcsb pdb:4ONN|rcsb pdb:4ORH|rcsb pdb:7BBF|reactome:R-HSA-5693565|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-5696395|reactome:R-HSA-69473|reactome:R-HSA-8866654|reactome:R-HSA-983168|rcsb pdb:7BBD|dip:DIP-29830N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/05 2017/08/10 rogid:ozxGwYPSrDJ+Fg3F64VfE0Bc0wM9606 rogid:i4SsftsLfkr72ufUq4QZn571iDQ9606 rigid:W3yJmjXouErRnmSmRtjS2IFmDH4 false glutathione s tranferase tag:n-n - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q14527 uniprotkb:Q9NS91 intact:EBI-1045161|uniprotkb:Q14536|uniprotkb:Q16051|uniprotkb:Q7KYJ6|uniprotkb:Q86YA5|uniprotkb:Q92652|uniprotkb:Q96KM9|uniprotkb:D3DNH3|ensembl:ENSP00000308944|ensembl:ENSP00000376644|ensembl:ENSP00000420429 intact:EBI-2339393|uniprotkb:Q9NRT6|uniprotkb:Q58F55|ensembl:ENSP00000264926 psi-mi:hltf_human(display_long)|uniprotkb:SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3(gene name synonym)|uniprotkb:Sucrose nonfermenting protein 2-like 3(gene name synonym)|uniprotkb:DNA-binding protein/plasminogen activator inhibitor 1 regulator(gene name synonym)|uniprotkb:HIP116(gene name synonym)|uniprotkb:RING finger protein 80(gene name synonym)|uniprotkb:HLTF(gene name)|psi-mi:HLTF(display_short)|uniprotkb:HIP116A(gene name synonym)|uniprotkb:RNF80(gene name synonym)|uniprotkb:SNF2L3(gene name synonym)|uniprotkb:ZBU1(gene name synonym)|uniprotkb:SMARCA3(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase HLTF(gene name synonym) psi-mi:rad18_human(display_long)|uniprotkb:RAD18(gene name)|psi-mi:RAD18(display_short)|uniprotkb:RNF73(gene name synonym)|uniprotkb:Postreplication repair protein RAD18(gene name synonym)|uniprotkb:RING finger protein 73(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RAD18(gene name synonym) psi-mi:"MI:0096"(pull down) Unk et al. (2008) pubmed:18316726|doi:10.1073/pnas.0800563105|imex:IM-9180 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-15689547|imex:IM-9180-1|dip:DIP-59315E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001305863.1|refseq:NP_001305864.1|refseq:NP_003062.2|refseq:NP_620636.1|refseq:XP_016862568.1|dip:DIP-29828N|ensembl:ENSG00000071794(gene)|ensembl:ENST00000310053(transcript)|ensembl:ENST00000392912(transcript)|ensembl:ENST00000494055(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016020"(membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016818"(hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070615"|interpro:IPR000330(SNF2-related)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014905(HIRAN)|interpro:IPR017907|interpro:IPR027417|interpro:IPR038718|mint:Q14527|rcsb pdb:2MZN|rcsb pdb:4HRE|rcsb pdb:4HRH|rcsb pdb:4S0N|rcsb pdb:4XZF|rcsb pdb:4XZG|rcsb pdb:5BNH|rcsb pdb:5K5F|rcsb pdb:6KCS|reactome:R-HSA-8866654 refseq:NP_064550.3|ensembl:ENSP00000264926|dip:DIP-29831N|ensembl:ENSG00000070950(gene)|ensembl:ENST00000264926(transcript)|go:"GO:0000403"(Y-form DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005657"(replication fork)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0006281"(DNA repair)|go:"GO:0006301"(postreplication repair)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016604"(nuclear body)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042405"(nuclear inclusion body)|go:"GO:0042802"(identical protein binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0051984"(positive regulation of chromosome segregation)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0097505"(Rad6-Rad18 complex)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003034(DNA-binding SAP)|interpro:IPR006642(Zinc finger, Rad18-type putative)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR036361|interpro:IPR039577|mint:Q9NS91|rcsb pdb:2MRE|rcsb pdb:2MRF|rcsb pdb:2Y43|rcsb pdb:2YBF|rcsb pdb:5VF0|reactome:R-HSA-110314|reactome:R-HSA-8866654|go:"GO:0060548"(negative regulation of cell death) psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/05 2017/08/10 rogid:ozxGwYPSrDJ+Fg3F64VfE0Bc0wM9606 rogid:/HmKCLqG1BxzmIWCgVpOw/gzJc49606 rigid:W3yJmjXouErRnmSmRtjS2IFmDH4 false glutathione s tranferase tag:n-n - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q14527 uniprotkb:P63146 intact:EBI-1045161|uniprotkb:Q14536|uniprotkb:Q16051|uniprotkb:Q7KYJ6|uniprotkb:Q86YA5|uniprotkb:Q92652|uniprotkb:Q96KM9|uniprotkb:D3DNH3|ensembl:ENSP00000308944|ensembl:ENSP00000376644|ensembl:ENSP00000420429 intact:EBI-712629|uniprotkb:P23567|uniprotkb:Q4PJ15|ensembl:ENSP00000265339|uniprotkb:Q9D0J6|uniprotkb:B2R503|uniprotkb:D3DQA2 psi-mi:hltf_human(display_long)|uniprotkb:SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3(gene name synonym)|uniprotkb:Sucrose nonfermenting protein 2-like 3(gene name synonym)|uniprotkb:DNA-binding protein/plasminogen activator inhibitor 1 regulator(gene name synonym)|uniprotkb:HIP116(gene name synonym)|uniprotkb:RING finger protein 80(gene name synonym)|uniprotkb:HLTF(gene name)|psi-mi:HLTF(display_short)|uniprotkb:HIP116A(gene name synonym)|uniprotkb:RNF80(gene name synonym)|uniprotkb:SNF2L3(gene name synonym)|uniprotkb:ZBU1(gene name synonym)|uniprotkb:SMARCA3(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase HLTF(gene name synonym) psi-mi:ube2b_human(display_long)|uniprotkb:Ubiquitin-protein ligase B(gene name synonym)|uniprotkb:Ubiquitin carrier protein B(gene name synonym)|uniprotkb:RAD6 homolog B(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-17 kDa(gene name synonym)|uniprotkb:UBE2B(gene name)|psi-mi:UBE2B(display_short)|uniprotkb:RAD6B(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme B(gene name synonym) psi-mi:"MI:0096"(pull down) Unk et al. (2008) pubmed:18316726|doi:10.1073/pnas.0800563105|imex:IM-9180 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-15689547|imex:IM-9180-1|dip:DIP-59315E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001305863.1|refseq:NP_001305864.1|refseq:NP_003062.2|refseq:NP_620636.1|refseq:XP_016862568.1|dip:DIP-29828N|ensembl:ENSG00000071794(gene)|ensembl:ENST00000310053(transcript)|ensembl:ENST00000392912(transcript)|ensembl:ENST00000494055(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016020"(membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016818"(hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070615"|interpro:IPR000330(SNF2-related)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014905(HIRAN)|interpro:IPR017907|interpro:IPR027417|interpro:IPR038718|mint:Q14527|rcsb pdb:2MZN|rcsb pdb:4HRE|rcsb pdb:4HRH|rcsb pdb:4S0N|rcsb pdb:4XZF|rcsb pdb:4XZG|rcsb pdb:5BNH|rcsb pdb:5K5F|rcsb pdb:6KCS|reactome:R-HSA-8866654 ensembl:ENSG00000119048(gene)|ensembl:ENST00000265339(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000785"(chromatin)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001741"(XY body)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005657"(replication fork)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006281"(DNA repair)|go:"GO:0006301"(postreplication repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007288"(sperm axoneme assembly)|go:"GO:0009411"(response to UV)|go:"GO:0010845"(positive regulation of reciprocal meiotic recombination)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|interpro:IPR023313|mint:P63146|rcsb pdb:1JAS|rcsb pdb:1NXA|rcsb pdb:2Y4W|rcsb pdb:2YB6|rcsb pdb:2YBF|reactome:R-HSA-110314|reactome:R-HSA-8866652|reactome:R-HSA-8866654|reactome:R-HSA-983168|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0033128"(negative regulation of histone phosphorylation)|go:"GO:0033503"(HULC complex)|go:"GO:0033522"(histone H2A ubiquitination)|go:"GO:0042493"|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043951"(negative regulation of cAMP-mediated signaling)|go:"GO:0045141"(meiotic telomere clustering)|go:"GO:0050821"(protein stabilization)|go:"GO:0051026"(chiasma assembly)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070076"(histone lysine demethylation)|go:"GO:0070193"(synaptonemal complex organization)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070829"(obsolete heterochromatin maintenance)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|refseq:NP_003328.1|dip:DIP-29832N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/05 2017/08/10 rogid:ozxGwYPSrDJ+Fg3F64VfE0Bc0wM9606 rogid:JvcUPH+3qQXicPsIRFnW19NOc3c9606 rigid:W3yJmjXouErRnmSmRtjS2IFmDH4 false glutathione s tranferase tag:n-n - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P12004 intact:EBI-4399559 intact:EBI-358311|uniprotkb:B2R897|uniprotkb:D3DW02|ensembl:ENSP00000368438|ensembl:ENSP00000368458 dip:DIP-24261N psi-mi:pcna_human(display_long)|uniprotkb:PCNA(gene name)|psi-mi:PCNA(display_short)|uniprotkb:Cyclin(gene name synonym) psi-mi:ubiq_human(display_short)|psi-mi:EBI-4399559(display_long) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Unk et al. (2008) pubmed:18316726|doi:10.1073/pnas.0800563105|imex:IM-9180 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15689569|imex:IM-9180-5|dip:DIP-59316E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002583.1|refseq:NP_872590.1|ensembl:ENSG00000132646(gene)|ensembl:ENST00000379143(transcript)|ensembl:ENST00000379160(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000307"(cyclin-dependent protein kinase holoenzyme complex)|go:"GO:0000701"(purine-specific mismatch base pair DNA N-glycosylase activity)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005652"(nuclear lamina)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005657"(replication fork)|go:"GO:0005813"(centrosome)|go:"GO:0006272"(leading strand elongation)|go:"GO:0006287"(base-excision repair, gap-filling)|go:"GO:0006298"(mismatch repair)|go:"GO:0007507"(heart development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016604"(nuclear body)|go:"GO:0019899"(enzyme binding)|go:"GO:0019985"(translesion synthesis)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030337"(DNA polymerase processivity factor activity)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0030894"(replisome)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031297"(replication fork processing)|go:"GO:0032077"(positive regulation of deoxyribonuclease activity)|go:"GO:0032139"(dinucleotide insertion or deletion binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0032405"(MutLalpha complex binding)|go:"GO:0034644"(cellular response to UV)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043596"(nuclear replication fork)|go:"GO:0043626"(PCNA complex)|go:"GO:0044849"(estrous cycle)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0046686"(response to cadmium ion)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070557"(PCNA-p21 complex)|go:"GO:0071466"(cellular response to xenobiotic stimulus)|go:"GO:0071548"(response to dexamethasone)|go:"GO:0097421"(liver regeneration)|go:"GO:1900264"(positive regulation of DNA-directed DNA polymerase activity)|go:"GO:1902065"(response to L-glutamate)|go:"GO:1902990"(mitotic telomere maintenance via semi-conservative replication)|interpro:IPR000730(Proliferating cell nuclear antigen, PCNA)|interpro:IPR022648|interpro:IPR022649|interpro:IPR022659|mint:P12004|rcsb pdb:1AXC|rcsb pdb:1U76|rcsb pdb:1U7B|rcsb pdb:1UL1|rcsb pdb:1VYJ|rcsb pdb:1VYM|rcsb pdb:1W60|rcsb pdb:2ZVK|rcsb pdb:2ZVL|rcsb pdb:2ZVM|rcsb pdb:3JA9|rcsb pdb:3P87|rcsb pdb:3TBL|rcsb pdb:3VKX|rcsb pdb:3WGW|rcsb pdb:4D2G|rcsb pdb:4RJF|rcsb pdb:4ZTD|rcsb pdb:5E0T|rcsb pdb:5E0U|rcsb pdb:5E0V|rcsb pdb:5IY4|rcsb pdb:5MAV|rcsb pdb:5MLO|rcsb pdb:5MLW|reactome:R-HSA-5651801|rcsb pdb:5MOM|rcsb pdb:5YCO|rcsb pdb:5YD8|rcsb pdb:6CBI|rcsb pdb:6EHT|rcsb pdb:6FCM|rcsb pdb:6FCN|rcsb pdb:6GIS|rcsb pdb:6GWS|rcsb pdb:6HVO|rcsb pdb:6K3A|rcsb pdb:6QC0|rcsb pdb:6QCG|rcsb pdb:6S1M|rcsb pdb:6S1N|rcsb pdb:6S1O|rcsb pdb:6TNY|rcsb pdb:6TNZ|rcsb pdb:6VVO|rcsb pdb:7EFA|rcsb pdb:7KQ0|rcsb pdb:7KQ1|reactome:R-HSA-110312|reactome:R-HSA-110314|reactome:R-HSA-110320|reactome:R-HSA-1362277|reactome:R-HSA-174411|reactome:R-HSA-174414|reactome:R-HSA-174417|reactome:R-HSA-174437|reactome:R-HSA-4615885|reactome:R-HSA-5358565|reactome:R-HSA-5358606|reactome:R-HSA-5656121|reactome:R-HSA-5656169|reactome:R-HSA-5685942|reactome:R-HSA-5696397|reactome:R-HSA-5696400|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6804114|reactome:R-HSA-69091|reactome:R-HSA-69166|reactome:R-HSA-69183|reactome:R-HSA-69205|reactome:R-HSA-8866654|reactome:R-HSA-5655862|dip:DIP-1098N uniprotkb:UBIQ_HUMAN(see-also)|refseq:NP_066289.2 psi-mi:"MI:0465"(dip) - no-uniprot-update: full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/05 2017/08/15 rogid:5JUv5dKFwQAAaXm5aEiwCXVoAOM9606 rogid:dobaeYpohKyDSnm4fBbcy0ZbYwM9606 rigid:JYZas/C/4osd/Lht9TxKMh/bwho false ha tag:n-n his tag:0-0 - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) intact:EBI-4399559 uniprotkb:P12004 dip:DIP-24261N intact:EBI-358311|uniprotkb:B2R897|uniprotkb:D3DW02|ensembl:ENSP00000368438|ensembl:ENSP00000368458 psi-mi:ubiq_human(display_short)|psi-mi:EBI-4399559(display_long) psi-mi:pcna_human(display_long)|uniprotkb:PCNA(gene name)|psi-mi:PCNA(display_short)|uniprotkb:Cyclin(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Unk et al. (2008) pubmed:18316726|doi:10.1073/pnas.0800563105|imex:IM-9180 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15689590|imex:IM-9180-3|dip:DIP-59316E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:UBIQ_HUMAN(see-also)|refseq:NP_066289.2 refseq:NP_002583.1|refseq:NP_872590.1|ensembl:ENSG00000132646(gene)|ensembl:ENST00000379143(transcript)|ensembl:ENST00000379160(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000307"(cyclin-dependent protein kinase holoenzyme complex)|go:"GO:0000701"(purine-specific mismatch base pair DNA N-glycosylase activity)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005652"(nuclear lamina)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005657"(replication fork)|go:"GO:0005813"(centrosome)|go:"GO:0006272"(leading strand elongation)|go:"GO:0006287"(base-excision repair, gap-filling)|go:"GO:0006298"(mismatch repair)|go:"GO:0007507"(heart development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016604"(nuclear body)|go:"GO:0019899"(enzyme binding)|go:"GO:0019985"(translesion synthesis)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030337"(DNA polymerase processivity factor activity)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0030894"(replisome)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031297"(replication fork processing)|go:"GO:0032077"(positive regulation of deoxyribonuclease activity)|go:"GO:0032139"(dinucleotide insertion or deletion binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0032405"(MutLalpha complex binding)|go:"GO:0034644"(cellular response to UV)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043596"(nuclear replication fork)|go:"GO:0043626"(PCNA complex)|go:"GO:0044849"(estrous cycle)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0046686"(response to cadmium ion)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070557"(PCNA-p21 complex)|go:"GO:0071466"(cellular response to xenobiotic stimulus)|go:"GO:0071548"(response to dexamethasone)|go:"GO:0097421"(liver regeneration)|go:"GO:1900264"(positive regulation of DNA-directed DNA polymerase activity)|go:"GO:1902065"(response to L-glutamate)|go:"GO:1902990"(mitotic telomere maintenance via semi-conservative replication)|interpro:IPR000730(Proliferating cell nuclear antigen, PCNA)|interpro:IPR022648|interpro:IPR022649|interpro:IPR022659|mint:P12004|rcsb pdb:1AXC|rcsb pdb:1U76|rcsb pdb:1U7B|rcsb pdb:1UL1|rcsb pdb:1VYJ|rcsb pdb:1VYM|rcsb pdb:1W60|rcsb pdb:2ZVK|rcsb pdb:2ZVL|rcsb pdb:2ZVM|rcsb pdb:3JA9|rcsb pdb:3P87|rcsb pdb:3TBL|rcsb pdb:3VKX|rcsb pdb:3WGW|rcsb pdb:4D2G|rcsb pdb:4RJF|rcsb pdb:4ZTD|rcsb pdb:5E0T|rcsb pdb:5E0U|rcsb pdb:5E0V|rcsb pdb:5IY4|rcsb pdb:5MAV|rcsb pdb:5MLO|rcsb pdb:5MLW|reactome:R-HSA-5651801|rcsb pdb:5MOM|rcsb pdb:5YCO|rcsb pdb:5YD8|rcsb pdb:6CBI|rcsb pdb:6EHT|rcsb pdb:6FCM|rcsb pdb:6FCN|rcsb pdb:6GIS|rcsb pdb:6GWS|rcsb pdb:6HVO|rcsb pdb:6K3A|rcsb pdb:6QC0|rcsb pdb:6QCG|rcsb pdb:6S1M|rcsb pdb:6S1N|rcsb pdb:6S1O|rcsb pdb:6TNY|rcsb pdb:6TNZ|rcsb pdb:6VVO|rcsb pdb:7EFA|rcsb pdb:7KQ0|rcsb pdb:7KQ1|reactome:R-HSA-110312|reactome:R-HSA-110314|reactome:R-HSA-110320|reactome:R-HSA-1362277|reactome:R-HSA-174411|reactome:R-HSA-174414|reactome:R-HSA-174417|reactome:R-HSA-174437|reactome:R-HSA-4615885|reactome:R-HSA-5358565|reactome:R-HSA-5358606|reactome:R-HSA-5656121|reactome:R-HSA-5656169|reactome:R-HSA-5685942|reactome:R-HSA-5696397|reactome:R-HSA-5696400|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6804114|reactome:R-HSA-69091|reactome:R-HSA-69166|reactome:R-HSA-69183|reactome:R-HSA-69205|reactome:R-HSA-8866654|reactome:R-HSA-5655862|dip:DIP-1098N psi-mi:"MI:0465"(dip) no-uniprot-update: - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/05 2017/08/15 rogid:dobaeYpohKyDSnm4fBbcy0ZbYwM9606 rogid:5JUv5dKFwQAAaXm5aEiwCXVoAOM9606 rigid:JYZas/C/4osd/Lht9TxKMh/bwho false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) intact:EBI-4399559 uniprotkb:P12004 dip:DIP-24261N intact:EBI-358311|uniprotkb:B2R897|uniprotkb:D3DW02|ensembl:ENSP00000368438|ensembl:ENSP00000368458 psi-mi:ubiq_human(display_short)|psi-mi:EBI-4399559(display_long) psi-mi:pcna_human(display_long)|uniprotkb:PCNA(gene name)|psi-mi:PCNA(display_short)|uniprotkb:Cyclin(gene name synonym) psi-mi:"MI:0808"(comigration in sds page) Unk et al. (2008) pubmed:18316726|doi:10.1073/pnas.0800563105|imex:IM-9180 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0195"(covalent binding) psi-mi:"MI:0465"(DIP) intact:EBI-15689607|imex:IM-9180-4|dip:DIP-59316E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:UBIQ_HUMAN(see-also)|refseq:NP_066289.2 refseq:NP_002583.1|refseq:NP_872590.1|ensembl:ENSG00000132646(gene)|ensembl:ENST00000379143(transcript)|ensembl:ENST00000379160(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000307"(cyclin-dependent protein kinase holoenzyme complex)|go:"GO:0000701"(purine-specific mismatch base pair DNA N-glycosylase activity)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005652"(nuclear lamina)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005657"(replication fork)|go:"GO:0005813"(centrosome)|go:"GO:0006272"(leading strand elongation)|go:"GO:0006287"(base-excision repair, gap-filling)|go:"GO:0006298"(mismatch repair)|go:"GO:0007507"(heart development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016604"(nuclear body)|go:"GO:0019899"(enzyme binding)|go:"GO:0019985"(translesion synthesis)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030337"(DNA polymerase processivity factor activity)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0030894"(replisome)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031297"(replication fork processing)|go:"GO:0032077"(positive regulation of deoxyribonuclease activity)|go:"GO:0032139"(dinucleotide insertion or deletion binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0032405"(MutLalpha complex binding)|go:"GO:0034644"(cellular response to UV)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043596"(nuclear replication fork)|go:"GO:0043626"(PCNA complex)|go:"GO:0044849"(estrous cycle)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0046686"(response to cadmium ion)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070557"(PCNA-p21 complex)|go:"GO:0071466"(cellular response to xenobiotic stimulus)|go:"GO:0071548"(response to dexamethasone)|go:"GO:0097421"(liver regeneration)|go:"GO:1900264"(positive regulation of DNA-directed DNA polymerase activity)|go:"GO:1902065"(response to L-glutamate)|go:"GO:1902990"(mitotic telomere maintenance via semi-conservative replication)|interpro:IPR000730(Proliferating cell nuclear antigen, PCNA)|interpro:IPR022648|interpro:IPR022649|interpro:IPR022659|mint:P12004|rcsb pdb:1AXC|rcsb pdb:1U76|rcsb pdb:1U7B|rcsb pdb:1UL1|rcsb pdb:1VYJ|rcsb pdb:1VYM|rcsb pdb:1W60|rcsb pdb:2ZVK|rcsb pdb:2ZVL|rcsb pdb:2ZVM|rcsb pdb:3JA9|rcsb pdb:3P87|rcsb pdb:3TBL|rcsb pdb:3VKX|rcsb pdb:3WGW|rcsb pdb:4D2G|rcsb pdb:4RJF|rcsb pdb:4ZTD|rcsb pdb:5E0T|rcsb pdb:5E0U|rcsb pdb:5E0V|rcsb pdb:5IY4|rcsb pdb:5MAV|rcsb pdb:5MLO|rcsb pdb:5MLW|reactome:R-HSA-5651801|rcsb pdb:5MOM|rcsb pdb:5YCO|rcsb pdb:5YD8|rcsb pdb:6CBI|rcsb pdb:6EHT|rcsb pdb:6FCM|rcsb pdb:6FCN|rcsb pdb:6GIS|rcsb pdb:6GWS|rcsb pdb:6HVO|rcsb pdb:6K3A|rcsb pdb:6QC0|rcsb pdb:6QCG|rcsb pdb:6S1M|rcsb pdb:6S1N|rcsb pdb:6S1O|rcsb pdb:6TNY|rcsb pdb:6TNZ|rcsb pdb:6VVO|rcsb pdb:7EFA|rcsb pdb:7KQ0|rcsb pdb:7KQ1|reactome:R-HSA-110312|reactome:R-HSA-110314|reactome:R-HSA-110320|reactome:R-HSA-1362277|reactome:R-HSA-174411|reactome:R-HSA-174414|reactome:R-HSA-174417|reactome:R-HSA-174437|reactome:R-HSA-4615885|reactome:R-HSA-5358565|reactome:R-HSA-5358606|reactome:R-HSA-5656121|reactome:R-HSA-5656169|reactome:R-HSA-5685942|reactome:R-HSA-5696397|reactome:R-HSA-5696400|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6804114|reactome:R-HSA-69091|reactome:R-HSA-69166|reactome:R-HSA-69183|reactome:R-HSA-69205|reactome:R-HSA-8866654|reactome:R-HSA-5655862|dip:DIP-1098N psi-mi:"MI:0465"(dip) no-uniprot-update: - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/05 2017/08/15 rogid:dobaeYpohKyDSnm4fBbcy0ZbYwM9606 rogid:5JUv5dKFwQAAaXm5aEiwCXVoAOM9606 rigid:JYZas/C/4osd/Lht9TxKMh/bwho false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot)