#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P0A742 uniprotkb:P0A742 intact:EBI-909797|ensemblbacteria:AAC76316|ensemblbacteria:BAE78001|uniprotkb:P23867|uniprotkb:Q2M6V5 intact:EBI-909797|ensemblbacteria:AAC76316|ensemblbacteria:BAE78001|uniprotkb:P23867|uniprotkb:Q2M6V5 psi-mi:mscl_ecoli(display_long)|uniprotkb:mscL(gene name)|psi-mi:mscL(display_short)|uniprotkb:b3291(locus name)|uniprotkb:JW3252(locus name)|uniprotkb:yhdC(gene name synonym) psi-mi:mscl_ecoli(display_long)|uniprotkb:mscL(gene name)|psi-mi:mscL(display_short)|uniprotkb:b3291(locus name)|uniprotkb:JW3252(locus name)|uniprotkb:yhdC(gene name synonym) psi-mi:"MI:0030"(cross-linking study) Yoshimura et al. (2008) pubmed:18310324|doi:10.1073/pnas.0709436105|imex:IM-9179 taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15689456|imex:IM-9179-3|dip:DIP-59313E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0006811"(ion transport)|go:"GO:0008381"(mechanosensitive ion channel activity)|ensemblbacteria:AAC76316(transcript)|ensemblbacteria:b3291(gene)|ensemblbacteria:BAE78001(gene)|ensemblbacteria:BAE78001(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0009992"(cellular water homeostasis)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0042802"(identical protein binding)|interpro:IPR001185(Large-conductance mechanosensitive channel)|interpro:IPR019823|interpro:IPR036019|interpro:IPR037673|rcsb pdb:1KYK|rcsb pdb:1KYL|rcsb pdb:1KYM|rcsb pdb:4LKU|refseq:NP_417749.1|refseq:WP_000022442.1|dip:DIP-29827N go:"GO:0006811"(ion transport)|go:"GO:0008381"(mechanosensitive ion channel activity)|ensemblbacteria:AAC76316(transcript)|ensemblbacteria:b3291(gene)|ensemblbacteria:BAE78001(gene)|ensemblbacteria:BAE78001(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0009992"(cellular water homeostasis)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0042802"(identical protein binding)|interpro:IPR001185(Large-conductance mechanosensitive channel)|interpro:IPR019823|interpro:IPR036019|interpro:IPR037673|rcsb pdb:1KYK|rcsb pdb:1KYL|rcsb pdb:1KYM|rcsb pdb:4LKU|refseq:NP_417749.1|refseq:WP_000022442.1|dip:DIP-29827N psi-mi:"MI:0465"(dip) crc64:18EF7E1BD7DF9491 crc64:18EF7E1BD7DF9491 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/05 2017/08/10 rogid:NZFN3l8Q4V5JlMg2ePALtfc/5/c83333 rogid:NZFN3l8Q4V5JlMg2ePALtfc/5/c83333 rigid:PLszzM/ba9zcNqtr7xt9GHHdvGg false - - - 0 psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P0A742 uniprotkb:P0A742 intact:EBI-909797|ensemblbacteria:AAC76316|ensemblbacteria:BAE78001|uniprotkb:P23867|uniprotkb:Q2M6V5 intact:EBI-909797|ensemblbacteria:AAC76316|ensemblbacteria:BAE78001|uniprotkb:P23867|uniprotkb:Q2M6V5 psi-mi:mscl_ecoli(display_long)|uniprotkb:mscL(gene name)|psi-mi:mscL(display_short)|uniprotkb:b3291(locus name)|uniprotkb:JW3252(locus name)|uniprotkb:yhdC(gene name synonym) psi-mi:mscl_ecoli(display_long)|uniprotkb:mscL(gene name)|psi-mi:mscL(display_short)|uniprotkb:b3291(locus name)|uniprotkb:JW3252(locus name)|uniprotkb:yhdC(gene name synonym) psi-mi:"MI:0030"(cross-linking study) Yoshimura et al. (2008) pubmed:18310324|doi:10.1073/pnas.0709436105|imex:IM-9179 taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15689472|imex:IM-9179-1|dip:DIP-59313E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0006811"(ion transport)|go:"GO:0008381"(mechanosensitive ion channel activity)|ensemblbacteria:AAC76316(transcript)|ensemblbacteria:b3291(gene)|ensemblbacteria:BAE78001(gene)|ensemblbacteria:BAE78001(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0009992"(cellular water homeostasis)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0042802"(identical protein binding)|interpro:IPR001185(Large-conductance mechanosensitive channel)|interpro:IPR019823|interpro:IPR036019|interpro:IPR037673|rcsb pdb:1KYK|rcsb pdb:1KYL|rcsb pdb:1KYM|rcsb pdb:4LKU|refseq:NP_417749.1|refseq:WP_000022442.1|dip:DIP-29827N go:"GO:0006811"(ion transport)|go:"GO:0008381"(mechanosensitive ion channel activity)|ensemblbacteria:AAC76316(transcript)|ensemblbacteria:b3291(gene)|ensemblbacteria:BAE78001(gene)|ensemblbacteria:BAE78001(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0009992"(cellular water homeostasis)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0042802"(identical protein binding)|interpro:IPR001185(Large-conductance mechanosensitive channel)|interpro:IPR019823|interpro:IPR036019|interpro:IPR037673|rcsb pdb:1KYK|rcsb pdb:1KYL|rcsb pdb:1KYM|rcsb pdb:4LKU|refseq:NP_417749.1|refseq:WP_000022442.1|dip:DIP-29827N psi-mi:"MI:0465"(dip) crc64:18EF7E1BD7DF9491 crc64:18EF7E1BD7DF9491 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/05 2017/08/10 rogid:NZFN3l8Q4V5JlMg2ePALtfc/5/c83333 rogid:NZFN3l8Q4V5JlMg2ePALtfc/5/c83333 rigid:PLszzM/ba9zcNqtr7xt9GHHdvGg false binding-associated region:1-109|his tag:n-n binding-associated region:1-109|his tag:n-n - 0 psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P0A742 uniprotkb:P0A742 intact:EBI-909797|ensemblbacteria:AAC76316|ensemblbacteria:BAE78001|uniprotkb:P23867|uniprotkb:Q2M6V5 intact:EBI-909797|ensemblbacteria:AAC76316|ensemblbacteria:BAE78001|uniprotkb:P23867|uniprotkb:Q2M6V5 psi-mi:mscl_ecoli(display_long)|uniprotkb:mscL(gene name)|psi-mi:mscL(display_short)|uniprotkb:b3291(locus name)|uniprotkb:JW3252(locus name)|uniprotkb:yhdC(gene name synonym) psi-mi:mscl_ecoli(display_long)|uniprotkb:mscL(gene name)|psi-mi:mscL(display_short)|uniprotkb:b3291(locus name)|uniprotkb:JW3252(locus name)|uniprotkb:yhdC(gene name synonym) psi-mi:"MI:0410"(3D electron microscopy) Yoshimura et al. (2008) pubmed:18310324|doi:10.1073/pnas.0709436105|imex:IM-9179 taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15689492|imex:IM-9179-2|dip:DIP-59313E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0006811"(ion transport)|go:"GO:0008381"(mechanosensitive ion channel activity)|ensemblbacteria:AAC76316(transcript)|ensemblbacteria:b3291(gene)|ensemblbacteria:BAE78001(gene)|ensemblbacteria:BAE78001(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0009992"(cellular water homeostasis)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0042802"(identical protein binding)|interpro:IPR001185(Large-conductance mechanosensitive channel)|interpro:IPR019823|interpro:IPR036019|interpro:IPR037673|rcsb pdb:1KYK|rcsb pdb:1KYL|rcsb pdb:1KYM|rcsb pdb:4LKU|refseq:NP_417749.1|refseq:WP_000022442.1|dip:DIP-29827N go:"GO:0006811"(ion transport)|go:"GO:0008381"(mechanosensitive ion channel activity)|ensemblbacteria:AAC76316(transcript)|ensemblbacteria:b3291(gene)|ensemblbacteria:BAE78001(gene)|ensemblbacteria:BAE78001(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0009992"(cellular water homeostasis)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0042802"(identical protein binding)|interpro:IPR001185(Large-conductance mechanosensitive channel)|interpro:IPR019823|interpro:IPR036019|interpro:IPR037673|rcsb pdb:1KYK|rcsb pdb:1KYL|rcsb pdb:1KYM|rcsb pdb:4LKU|refseq:NP_417749.1|refseq:WP_000022442.1|dip:DIP-29827N psi-mi:"MI:0465"(dip) crc64:18EF7E1BD7DF9491 crc64:18EF7E1BD7DF9491 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/05 2017/08/10 rogid:NZFN3l8Q4V5JlMg2ePALtfc/5/c83333 rogid:NZFN3l8Q4V5JlMg2ePALtfc/5/c83333 rigid:PLszzM/ba9zcNqtr7xt9GHHdvGg false - - - 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)