#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P11498	uniprotkb:P11498	intact:EBI-2211322|uniprotkb:Q16705|uniprotkb:B4DN00|ensembl:ENSP00000377527|ensembl:ENSP00000377530|ensembl:ENSP00000377532|ensembl:ENSP00000435905|ensembl:ENSP00000498302|ensembl:ENSP00000498406|ensembl:ENSP00000498994	intact:EBI-2211322|uniprotkb:Q16705|uniprotkb:B4DN00|ensembl:ENSP00000377527|ensembl:ENSP00000377530|ensembl:ENSP00000377532|ensembl:ENSP00000435905|ensembl:ENSP00000498302|ensembl:ENSP00000498406|ensembl:ENSP00000498994	psi-mi:pyc_human(display_long)|uniprotkb:PC(gene name)|psi-mi:PC(display_short)|uniprotkb:Pyruvic carboxylase(gene name synonym)	psi-mi:pyc_human(display_long)|uniprotkb:PC(gene name)|psi-mi:PC(display_short)|uniprotkb:Pyruvic carboxylase(gene name synonym)	psi-mi:"MI:0071"(molecular sieving)	Xiang et al. (2008)	pubmed:18297087|doi:10.1038/nsmb.1393|imex:IM-9629	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-16218384|imex:IM-9629-5|dip:DIP-88352E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011543388.1|refseq:XP_016873357.1|refseq:XP_016873358.1|refseq:XP_016873359.1|refseq:XP_016873360.1|refseq:XP_016873361.1|refseq:NP_000911.2|refseq:NP_001035806.1|refseq:NP_071504.2|refseq:XP_005274088.1|refseq:XP_005274089.1|refseq:XP_006718641.1|dip:DIP-46372N|ensembl:ENSG00000173599(gene)|ensembl:ENST00000393955(transcript)|ensembl:ENST00000393958(transcript)|ensembl:ENST00000393960(transcript)|ensembl:ENST00000529047(transcript)|ensembl:ENST00000651036(transcript)|ensembl:ENST00000651854(transcript)|ensembl:ENST00000652125(transcript)|go:"GO:0004736"(pyruvate carboxylase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006090"(pyruvate metabolic process)|go:"GO:0006094"(gluconeogenesis)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0009374"(biotin binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0019074"(viral RNA genome packaging)|go:"GO:0042802"(identical protein binding)|go:"GO:0044791"(obsolete positive regulation by host of viral release from host cell)|go:"GO:0044794"(positive regulation by host of viral process)|go:"GO:0046872"(metal ion binding)|interpro:IPR000089(Biotin/lipoyl attachment)|interpro:IPR000891(Pyruvate carboxyltransferase)|interpro:IPR001882(Biotin-binding site)|interpro:IPR003379(Conserved carboxylase region)|interpro:IPR005479(Carbamoyl phosphate synthetase, large subunit, ATP-binding)|interpro:IPR005481(Carbamoyl phosphate synthase, large subunit, N-terminal)|interpro:IPR005482(Biotin carboxylase, C-terminal)|interpro:IPR005930(Pyruvate carboxylase)|interpro:IPR011053(Single hybrid motif)|interpro:IPR011054(Rudiment single hybrid motif)|interpro:IPR011761(ATP-grasp fold)|interpro:IPR011764(Biotin carboxylation region)|interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR016185(PreATP-grasp-like fold)|mint:P11498|rcsb pdb:3BG3|rcsb pdb:3BG9|reactome:R-HSA-196780|reactome:R-HSA-3371599|reactome:R-HSA-70263	refseq:XP_011543388.1|refseq:XP_016873357.1|refseq:XP_016873358.1|refseq:XP_016873359.1|refseq:XP_016873360.1|refseq:XP_016873361.1|refseq:NP_000911.2|refseq:NP_001035806.1|refseq:NP_071504.2|refseq:XP_005274088.1|refseq:XP_005274089.1|refseq:XP_006718641.1|dip:DIP-46372N|ensembl:ENSG00000173599(gene)|ensembl:ENST00000393955(transcript)|ensembl:ENST00000393958(transcript)|ensembl:ENST00000393960(transcript)|ensembl:ENST00000529047(transcript)|ensembl:ENST00000651036(transcript)|ensembl:ENST00000651854(transcript)|ensembl:ENST00000652125(transcript)|go:"GO:0004736"(pyruvate carboxylase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006090"(pyruvate metabolic process)|go:"GO:0006094"(gluconeogenesis)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0009374"(biotin binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0019074"(viral RNA genome packaging)|go:"GO:0042802"(identical protein binding)|go:"GO:0044791"(obsolete positive regulation by host of viral release from host cell)|go:"GO:0044794"(positive regulation by host of viral process)|go:"GO:0046872"(metal ion binding)|interpro:IPR000089(Biotin/lipoyl attachment)|interpro:IPR000891(Pyruvate carboxyltransferase)|interpro:IPR001882(Biotin-binding site)|interpro:IPR003379(Conserved carboxylase region)|interpro:IPR005479(Carbamoyl phosphate synthetase, large subunit, ATP-binding)|interpro:IPR005481(Carbamoyl phosphate synthase, large subunit, N-terminal)|interpro:IPR005482(Biotin carboxylase, C-terminal)|interpro:IPR005930(Pyruvate carboxylase)|interpro:IPR011053(Single hybrid motif)|interpro:IPR011054(Rudiment single hybrid motif)|interpro:IPR011761(ATP-grasp fold)|interpro:IPR011764(Biotin carboxylation region)|interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR016185(PreATP-grasp-like fold)|mint:P11498|rcsb pdb:3BG3|rcsb pdb:3BG9|reactome:R-HSA-196780|reactome:R-HSA-3371599|reactome:R-HSA-70263	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:562(ecolx)|taxid:562(Escherichia coli)	-	2017/08/09	2017/08/10	rogid:0xXv1wxe0AC1EO7wxSDVhBpHCUU9606	rogid:0xXv1wxe0AC1EO7wxSDVhBpHCUU9606	rigid:6sZLVjf8xABAqj6jB74FNj/+VJU	false	binding-associated region:482-1178	binding-associated region:482-1178	-	0	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:A0A0H3JRU9	uniprotkb:A0A0H3JRU9	intact:EBI-16108775|ensemblbacteria:BAB57276	intact:EBI-16108775|ensemblbacteria:BAB57276	psi-mi:pyc_staam(display_long)|uniprotkb:pycA(gene name)|psi-mi:pycA(display_short)|uniprotkb:SAV1114(locus name)	psi-mi:pyc_staam(display_long)|uniprotkb:pycA(gene name)|psi-mi:pycA(display_short)|uniprotkb:SAV1114(locus name)	psi-mi:"MI:0071"(molecular sieving)	Xiang et al. (2008)	pubmed:18297087|doi:10.1038/nsmb.1393|imex:IM-9629	taxid:158878(staam)|taxid:158878("Staphylococcus aureus (strain Mu50 / ATCC 700699)")	taxid:158878(staam)|taxid:158878("Staphylococcus aureus (strain Mu50 / ATCC 700699)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-16218402|imex:IM-9629-6|dip:DIP-88353E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblbacteria:BAB57276(transcript)|ensemblbacteria:SAV1114(gene)|go:"GO:0004736"(pyruvate carboxylase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006090"(pyruvate metabolic process)|go:"GO:0006094"(gluconeogenesis)|go:"GO:0009374"(biotin binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|uniprotkb:Q99UY8(uniprot-removed-ac)|interpro:IPR000089(Biotin/lipoyl attachment)|interpro:IPR000891(Pyruvate carboxyltransferase)|interpro:IPR003379(Conserved carboxylase region)|interpro:IPR005479(Carbamoyl phosphate synthetase, large subunit, ATP-binding)|interpro:IPR005481(Carbamoyl phosphate synthase, large subunit, N-terminal)|interpro:IPR005482(Biotin carboxylase, C-terminal)|interpro:IPR005930(Pyruvate carboxylase)|interpro:IPR011053(Single hybrid motif)|interpro:IPR011054(Rudiment single hybrid motif)|interpro:IPR011761(ATP-grasp fold)|interpro:IPR011764(Biotin carboxylation region)|interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR016185(PreATP-grasp-like fold)|rcsb pdb:3BG5|rcsb pdb:3HB9|rcsb pdb:3HBL|rcsb pdb:3HO8|rcsb pdb:4HNT|rcsb pdb:4HNU|rcsb pdb:4HNV|refseq:WP_000809514.1	ensemblbacteria:BAB57276(transcript)|ensemblbacteria:SAV1114(gene)|go:"GO:0004736"(pyruvate carboxylase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006090"(pyruvate metabolic process)|go:"GO:0006094"(gluconeogenesis)|go:"GO:0009374"(biotin binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|uniprotkb:Q99UY8(uniprot-removed-ac)|interpro:IPR000089(Biotin/lipoyl attachment)|interpro:IPR000891(Pyruvate carboxyltransferase)|interpro:IPR003379(Conserved carboxylase region)|interpro:IPR005479(Carbamoyl phosphate synthetase, large subunit, ATP-binding)|interpro:IPR005481(Carbamoyl phosphate synthase, large subunit, N-terminal)|interpro:IPR005482(Biotin carboxylase, C-terminal)|interpro:IPR005930(Pyruvate carboxylase)|interpro:IPR011053(Single hybrid motif)|interpro:IPR011054(Rudiment single hybrid motif)|interpro:IPR011761(ATP-grasp fold)|interpro:IPR011764(Biotin carboxylation region)|interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR016185(PreATP-grasp-like fold)|rcsb pdb:3BG5|rcsb pdb:3HB9|rcsb pdb:3HBL|rcsb pdb:3HO8|rcsb pdb:4HNT|rcsb pdb:4HNU|rcsb pdb:4HNV|refseq:WP_000809514.1	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:562(ecolx)|taxid:562(Escherichia coli)	-	2017/08/09	2017/08/12	rogid:yvYuCnqdsZnHaktHz14e0oStyTc158878	rogid:yvYuCnqdsZnHaktHz14e0oStyTc158878	rigid:WcvMZ+vRlJUx44LO6u2LxeVukdY	false	-	-	-	0	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:A0A0H3JRU9	uniprotkb:A0A0H3JRU9	intact:EBI-16108775|ensemblbacteria:BAB57276	intact:EBI-16108775|ensemblbacteria:BAB57276	psi-mi:pyc_staam(display_long)|uniprotkb:pycA(gene name)|psi-mi:pycA(display_short)|uniprotkb:SAV1114(locus name)	psi-mi:pyc_staam(display_long)|uniprotkb:pycA(gene name)|psi-mi:pycA(display_short)|uniprotkb:SAV1114(locus name)	psi-mi:"MI:0067"(light scattering)	Xiang et al. (2008)	pubmed:18297087|doi:10.1038/nsmb.1393|imex:IM-9629	taxid:158878(staam)|taxid:158878("Staphylococcus aureus (strain Mu50 / ATCC 700699)")	taxid:158878(staam)|taxid:158878("Staphylococcus aureus (strain Mu50 / ATCC 700699)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-16218418|imex:IM-9629-1|dip:DIP-88353E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblbacteria:BAB57276(transcript)|ensemblbacteria:SAV1114(gene)|go:"GO:0004736"(pyruvate carboxylase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006090"(pyruvate metabolic process)|go:"GO:0006094"(gluconeogenesis)|go:"GO:0009374"(biotin binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|uniprotkb:Q99UY8(uniprot-removed-ac)|interpro:IPR000089(Biotin/lipoyl attachment)|interpro:IPR000891(Pyruvate carboxyltransferase)|interpro:IPR003379(Conserved carboxylase region)|interpro:IPR005479(Carbamoyl phosphate synthetase, large subunit, ATP-binding)|interpro:IPR005481(Carbamoyl phosphate synthase, large subunit, N-terminal)|interpro:IPR005482(Biotin carboxylase, C-terminal)|interpro:IPR005930(Pyruvate carboxylase)|interpro:IPR011053(Single hybrid motif)|interpro:IPR011054(Rudiment single hybrid motif)|interpro:IPR011761(ATP-grasp fold)|interpro:IPR011764(Biotin carboxylation region)|interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR016185(PreATP-grasp-like fold)|rcsb pdb:3BG5|rcsb pdb:3HB9|rcsb pdb:3HBL|rcsb pdb:3HO8|rcsb pdb:4HNT|rcsb pdb:4HNU|rcsb pdb:4HNV|refseq:WP_000809514.1	ensemblbacteria:BAB57276(transcript)|ensemblbacteria:SAV1114(gene)|go:"GO:0004736"(pyruvate carboxylase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006090"(pyruvate metabolic process)|go:"GO:0006094"(gluconeogenesis)|go:"GO:0009374"(biotin binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|uniprotkb:Q99UY8(uniprot-removed-ac)|interpro:IPR000089(Biotin/lipoyl attachment)|interpro:IPR000891(Pyruvate carboxyltransferase)|interpro:IPR003379(Conserved carboxylase region)|interpro:IPR005479(Carbamoyl phosphate synthetase, large subunit, ATP-binding)|interpro:IPR005481(Carbamoyl phosphate synthase, large subunit, N-terminal)|interpro:IPR005482(Biotin carboxylase, C-terminal)|interpro:IPR005930(Pyruvate carboxylase)|interpro:IPR011053(Single hybrid motif)|interpro:IPR011054(Rudiment single hybrid motif)|interpro:IPR011761(ATP-grasp fold)|interpro:IPR011764(Biotin carboxylation region)|interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR016185(PreATP-grasp-like fold)|rcsb pdb:3BG5|rcsb pdb:3HB9|rcsb pdb:3HBL|rcsb pdb:3HO8|rcsb pdb:4HNT|rcsb pdb:4HNU|rcsb pdb:4HNV|refseq:WP_000809514.1	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:562(ecolx)|taxid:562(Escherichia coli)	-	2017/08/09	2017/08/12	rogid:yvYuCnqdsZnHaktHz14e0oStyTc158878	rogid:yvYuCnqdsZnHaktHz14e0oStyTc158878	rigid:WcvMZ+vRlJUx44LO6u2LxeVukdY	false	-	-	-	0	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P11498	uniprotkb:P11498	intact:EBI-2211322|uniprotkb:Q16705|uniprotkb:B4DN00|ensembl:ENSP00000377527|ensembl:ENSP00000377530|ensembl:ENSP00000377532|ensembl:ENSP00000435905|ensembl:ENSP00000498302|ensembl:ENSP00000498406|ensembl:ENSP00000498994	intact:EBI-2211322|uniprotkb:Q16705|uniprotkb:B4DN00|ensembl:ENSP00000377527|ensembl:ENSP00000377530|ensembl:ENSP00000377532|ensembl:ENSP00000435905|ensembl:ENSP00000498302|ensembl:ENSP00000498406|ensembl:ENSP00000498994	psi-mi:pyc_human(display_long)|uniprotkb:PC(gene name)|psi-mi:PC(display_short)|uniprotkb:Pyruvic carboxylase(gene name synonym)	psi-mi:pyc_human(display_long)|uniprotkb:PC(gene name)|psi-mi:PC(display_short)|uniprotkb:Pyruvic carboxylase(gene name synonym)	psi-mi:"MI:0067"(light scattering)	Xiang et al. (2008)	pubmed:18297087|doi:10.1038/nsmb.1393|imex:IM-9629	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-16218434|imex:IM-9629-2|dip:DIP-88352E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011543388.1|refseq:XP_016873357.1|refseq:XP_016873358.1|refseq:XP_016873359.1|refseq:XP_016873360.1|refseq:XP_016873361.1|refseq:NP_000911.2|refseq:NP_001035806.1|refseq:NP_071504.2|refseq:XP_005274088.1|refseq:XP_005274089.1|refseq:XP_006718641.1|dip:DIP-46372N|ensembl:ENSG00000173599(gene)|ensembl:ENST00000393955(transcript)|ensembl:ENST00000393958(transcript)|ensembl:ENST00000393960(transcript)|ensembl:ENST00000529047(transcript)|ensembl:ENST00000651036(transcript)|ensembl:ENST00000651854(transcript)|ensembl:ENST00000652125(transcript)|go:"GO:0004736"(pyruvate carboxylase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006090"(pyruvate metabolic process)|go:"GO:0006094"(gluconeogenesis)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0009374"(biotin binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0019074"(viral RNA genome packaging)|go:"GO:0042802"(identical protein binding)|go:"GO:0044791"(obsolete positive regulation by host of viral release from host cell)|go:"GO:0044794"(positive regulation by host of viral process)|go:"GO:0046872"(metal ion binding)|interpro:IPR000089(Biotin/lipoyl attachment)|interpro:IPR000891(Pyruvate carboxyltransferase)|interpro:IPR001882(Biotin-binding site)|interpro:IPR003379(Conserved carboxylase region)|interpro:IPR005479(Carbamoyl phosphate synthetase, large subunit, ATP-binding)|interpro:IPR005481(Carbamoyl phosphate synthase, large subunit, N-terminal)|interpro:IPR005482(Biotin carboxylase, C-terminal)|interpro:IPR005930(Pyruvate carboxylase)|interpro:IPR011053(Single hybrid motif)|interpro:IPR011054(Rudiment single hybrid motif)|interpro:IPR011761(ATP-grasp fold)|interpro:IPR011764(Biotin carboxylation region)|interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR016185(PreATP-grasp-like fold)|mint:P11498|rcsb pdb:3BG3|rcsb pdb:3BG9|reactome:R-HSA-196780|reactome:R-HSA-3371599|reactome:R-HSA-70263	refseq:XP_011543388.1|refseq:XP_016873357.1|refseq:XP_016873358.1|refseq:XP_016873359.1|refseq:XP_016873360.1|refseq:XP_016873361.1|refseq:NP_000911.2|refseq:NP_001035806.1|refseq:NP_071504.2|refseq:XP_005274088.1|refseq:XP_005274089.1|refseq:XP_006718641.1|dip:DIP-46372N|ensembl:ENSG00000173599(gene)|ensembl:ENST00000393955(transcript)|ensembl:ENST00000393958(transcript)|ensembl:ENST00000393960(transcript)|ensembl:ENST00000529047(transcript)|ensembl:ENST00000651036(transcript)|ensembl:ENST00000651854(transcript)|ensembl:ENST00000652125(transcript)|go:"GO:0004736"(pyruvate carboxylase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006090"(pyruvate metabolic process)|go:"GO:0006094"(gluconeogenesis)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0009374"(biotin binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0019074"(viral RNA genome packaging)|go:"GO:0042802"(identical protein binding)|go:"GO:0044791"(obsolete positive regulation by host of viral release from host cell)|go:"GO:0044794"(positive regulation by host of viral process)|go:"GO:0046872"(metal ion binding)|interpro:IPR000089(Biotin/lipoyl attachment)|interpro:IPR000891(Pyruvate carboxyltransferase)|interpro:IPR001882(Biotin-binding site)|interpro:IPR003379(Conserved carboxylase region)|interpro:IPR005479(Carbamoyl phosphate synthetase, large subunit, ATP-binding)|interpro:IPR005481(Carbamoyl phosphate synthase, large subunit, N-terminal)|interpro:IPR005482(Biotin carboxylase, C-terminal)|interpro:IPR005930(Pyruvate carboxylase)|interpro:IPR011053(Single hybrid motif)|interpro:IPR011054(Rudiment single hybrid motif)|interpro:IPR011761(ATP-grasp fold)|interpro:IPR011764(Biotin carboxylation region)|interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR016185(PreATP-grasp-like fold)|mint:P11498|rcsb pdb:3BG3|rcsb pdb:3BG9|reactome:R-HSA-196780|reactome:R-HSA-3371599|reactome:R-HSA-70263	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:562(ecolx)|taxid:562(Escherichia coli)	-	2017/08/09	2017/08/10	rogid:0xXv1wxe0AC1EO7wxSDVhBpHCUU9606	rogid:0xXv1wxe0AC1EO7wxSDVhBpHCUU9606	rigid:6sZLVjf8xABAqj6jB74FNj/+VJU	false	binding-associated region:482-1178	binding-associated region:482-1178	-	0	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:A0A0H3JRU9	uniprotkb:A0A0H3JRU9	intact:EBI-16108775|ensemblbacteria:BAB57276	intact:EBI-16108775|ensemblbacteria:BAB57276	psi-mi:pyc_staam(display_long)|uniprotkb:pycA(gene name)|psi-mi:pycA(display_short)|uniprotkb:SAV1114(locus name)	psi-mi:pyc_staam(display_long)|uniprotkb:pycA(gene name)|psi-mi:pycA(display_short)|uniprotkb:SAV1114(locus name)	psi-mi:"MI:0114"(x-ray crystallography)	Xiang et al. (2008)	pubmed:18297087|doi:10.1038/nsmb.1393|imex:IM-9629	taxid:158878(staam)|taxid:158878("Staphylococcus aureus (strain Mu50 / ATCC 700699)")	taxid:158878(staam)|taxid:158878("Staphylococcus aureus (strain Mu50 / ATCC 700699)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-16218453|imex:IM-9629-3|dip:DIP-88353E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblbacteria:BAB57276(transcript)|ensemblbacteria:SAV1114(gene)|go:"GO:0004736"(pyruvate carboxylase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006090"(pyruvate metabolic process)|go:"GO:0006094"(gluconeogenesis)|go:"GO:0009374"(biotin binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|uniprotkb:Q99UY8(uniprot-removed-ac)|interpro:IPR000089(Biotin/lipoyl attachment)|interpro:IPR000891(Pyruvate carboxyltransferase)|interpro:IPR003379(Conserved carboxylase region)|interpro:IPR005479(Carbamoyl phosphate synthetase, large subunit, ATP-binding)|interpro:IPR005481(Carbamoyl phosphate synthase, large subunit, N-terminal)|interpro:IPR005482(Biotin carboxylase, C-terminal)|interpro:IPR005930(Pyruvate carboxylase)|interpro:IPR011053(Single hybrid motif)|interpro:IPR011054(Rudiment single hybrid motif)|interpro:IPR011761(ATP-grasp fold)|interpro:IPR011764(Biotin carboxylation region)|interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR016185(PreATP-grasp-like fold)|rcsb pdb:3BG5|rcsb pdb:3HB9|rcsb pdb:3HBL|rcsb pdb:3HO8|rcsb pdb:4HNT|rcsb pdb:4HNU|rcsb pdb:4HNV|refseq:WP_000809514.1	ensemblbacteria:BAB57276(transcript)|ensemblbacteria:SAV1114(gene)|go:"GO:0004736"(pyruvate carboxylase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006090"(pyruvate metabolic process)|go:"GO:0006094"(gluconeogenesis)|go:"GO:0009374"(biotin binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|uniprotkb:Q99UY8(uniprot-removed-ac)|interpro:IPR000089(Biotin/lipoyl attachment)|interpro:IPR000891(Pyruvate carboxyltransferase)|interpro:IPR003379(Conserved carboxylase region)|interpro:IPR005479(Carbamoyl phosphate synthetase, large subunit, ATP-binding)|interpro:IPR005481(Carbamoyl phosphate synthase, large subunit, N-terminal)|interpro:IPR005482(Biotin carboxylase, C-terminal)|interpro:IPR005930(Pyruvate carboxylase)|interpro:IPR011053(Single hybrid motif)|interpro:IPR011054(Rudiment single hybrid motif)|interpro:IPR011761(ATP-grasp fold)|interpro:IPR011764(Biotin carboxylation region)|interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR016185(PreATP-grasp-like fold)|rcsb pdb:3BG5|rcsb pdb:3HB9|rcsb pdb:3HBL|rcsb pdb:3HO8|rcsb pdb:4HNT|rcsb pdb:4HNU|rcsb pdb:4HNV|refseq:WP_000809514.1	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:562(ecolx)|taxid:562(Escherichia coli)	-	2017/08/09	2017/08/12	rogid:yvYuCnqdsZnHaktHz14e0oStyTc158878	rogid:yvYuCnqdsZnHaktHz14e0oStyTc158878	rigid:WcvMZ+vRlJUx44LO6u2LxeVukdY	false	-	-	-	0	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P11498	uniprotkb:P11498	intact:EBI-2211322|uniprotkb:Q16705|uniprotkb:B4DN00|ensembl:ENSP00000377527|ensembl:ENSP00000377530|ensembl:ENSP00000377532|ensembl:ENSP00000435905|ensembl:ENSP00000498302|ensembl:ENSP00000498406|ensembl:ENSP00000498994	intact:EBI-2211322|uniprotkb:Q16705|uniprotkb:B4DN00|ensembl:ENSP00000377527|ensembl:ENSP00000377530|ensembl:ENSP00000377532|ensembl:ENSP00000435905|ensembl:ENSP00000498302|ensembl:ENSP00000498406|ensembl:ENSP00000498994	psi-mi:pyc_human(display_long)|uniprotkb:PC(gene name)|psi-mi:PC(display_short)|uniprotkb:Pyruvic carboxylase(gene name synonym)	psi-mi:pyc_human(display_long)|uniprotkb:PC(gene name)|psi-mi:PC(display_short)|uniprotkb:Pyruvic carboxylase(gene name synonym)	psi-mi:"MI:0114"(x-ray crystallography)	Xiang et al. (2008)	pubmed:18297087|doi:10.1038/nsmb.1393|imex:IM-9629	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-16218471|imex:IM-9629-4|dip:DIP-88352E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011543388.1|refseq:XP_016873357.1|refseq:XP_016873358.1|refseq:XP_016873359.1|refseq:XP_016873360.1|refseq:XP_016873361.1|refseq:NP_000911.2|refseq:NP_001035806.1|refseq:NP_071504.2|refseq:XP_005274088.1|refseq:XP_005274089.1|refseq:XP_006718641.1|dip:DIP-46372N|ensembl:ENSG00000173599(gene)|ensembl:ENST00000393955(transcript)|ensembl:ENST00000393958(transcript)|ensembl:ENST00000393960(transcript)|ensembl:ENST00000529047(transcript)|ensembl:ENST00000651036(transcript)|ensembl:ENST00000651854(transcript)|ensembl:ENST00000652125(transcript)|go:"GO:0004736"(pyruvate carboxylase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006090"(pyruvate metabolic process)|go:"GO:0006094"(gluconeogenesis)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0009374"(biotin binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0019074"(viral RNA genome packaging)|go:"GO:0042802"(identical protein binding)|go:"GO:0044791"(obsolete positive regulation by host of viral release from host cell)|go:"GO:0044794"(positive regulation by host of viral process)|go:"GO:0046872"(metal ion binding)|interpro:IPR000089(Biotin/lipoyl attachment)|interpro:IPR000891(Pyruvate carboxyltransferase)|interpro:IPR001882(Biotin-binding site)|interpro:IPR003379(Conserved carboxylase region)|interpro:IPR005479(Carbamoyl phosphate synthetase, large subunit, ATP-binding)|interpro:IPR005481(Carbamoyl phosphate synthase, large subunit, N-terminal)|interpro:IPR005482(Biotin carboxylase, C-terminal)|interpro:IPR005930(Pyruvate carboxylase)|interpro:IPR011053(Single hybrid motif)|interpro:IPR011054(Rudiment single hybrid motif)|interpro:IPR011761(ATP-grasp fold)|interpro:IPR011764(Biotin carboxylation region)|interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR016185(PreATP-grasp-like fold)|mint:P11498|rcsb pdb:3BG3|rcsb pdb:3BG9|reactome:R-HSA-196780|reactome:R-HSA-3371599|reactome:R-HSA-70263	refseq:XP_011543388.1|refseq:XP_016873357.1|refseq:XP_016873358.1|refseq:XP_016873359.1|refseq:XP_016873360.1|refseq:XP_016873361.1|refseq:NP_000911.2|refseq:NP_001035806.1|refseq:NP_071504.2|refseq:XP_005274088.1|refseq:XP_005274089.1|refseq:XP_006718641.1|dip:DIP-46372N|ensembl:ENSG00000173599(gene)|ensembl:ENST00000393955(transcript)|ensembl:ENST00000393958(transcript)|ensembl:ENST00000393960(transcript)|ensembl:ENST00000529047(transcript)|ensembl:ENST00000651036(transcript)|ensembl:ENST00000651854(transcript)|ensembl:ENST00000652125(transcript)|go:"GO:0004736"(pyruvate carboxylase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006090"(pyruvate metabolic process)|go:"GO:0006094"(gluconeogenesis)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0009374"(biotin binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0019074"(viral RNA genome packaging)|go:"GO:0042802"(identical protein binding)|go:"GO:0044791"(obsolete positive regulation by host of viral release from host cell)|go:"GO:0044794"(positive regulation by host of viral process)|go:"GO:0046872"(metal ion binding)|interpro:IPR000089(Biotin/lipoyl attachment)|interpro:IPR000891(Pyruvate carboxyltransferase)|interpro:IPR001882(Biotin-binding site)|interpro:IPR003379(Conserved carboxylase region)|interpro:IPR005479(Carbamoyl phosphate synthetase, large subunit, ATP-binding)|interpro:IPR005481(Carbamoyl phosphate synthase, large subunit, N-terminal)|interpro:IPR005482(Biotin carboxylase, C-terminal)|interpro:IPR005930(Pyruvate carboxylase)|interpro:IPR011053(Single hybrid motif)|interpro:IPR011054(Rudiment single hybrid motif)|interpro:IPR011761(ATP-grasp fold)|interpro:IPR011764(Biotin carboxylation region)|interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR016185(PreATP-grasp-like fold)|mint:P11498|rcsb pdb:3BG3|rcsb pdb:3BG9|reactome:R-HSA-196780|reactome:R-HSA-3371599|reactome:R-HSA-70263	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:562(ecolx)|taxid:562(Escherichia coli)	-	2017/08/09	2017/08/10	rogid:0xXv1wxe0AC1EO7wxSDVhBpHCUU9606	rogid:0xXv1wxe0AC1EO7wxSDVhBpHCUU9606	rigid:6sZLVjf8xABAqj6jB74FNj/+VJU	false	binding-associated region:482-1178	binding-associated region:482-1178	-	0	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)