#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q99755	uniprotkb:Q9H6E5	intact:EBI-726414|uniprotkb:Q99754|uniprotkb:Q99756|uniprotkb:B4DIN0|uniprotkb:A8K4Q0|ensembl:ENSP00000357883	intact:EBI-2511680|ensembl:ENSP00000419607|uniprotkb:Q9H6H7|uniprotkb:Q7L583|uniprotkb:Q2NL65|uniprotkb:A1A527|intact:EBI-2809257|uniprotkb:A8K995	psi-mi:pi51a_human(display_long)|uniprotkb:PIP5K1A(gene name)|psi-mi:PIP5K1A(display_short)|uniprotkb:68 kDa type I phosphatidylinositol 4-phosphate 5-kinase alpha(gene name synonym)|uniprotkb:Phosphatidylinositol 4-phosphate 5-kinase type I alpha(gene name synonym)	psi-mi:stpap_human(display_long)|uniprotkb:TUT1(gene name)|psi-mi:TUT1(display_short)|uniprotkb:RBM21(gene name synonym)|uniprotkb:RNA-binding motif protein 21(gene name synonym)|uniprotkb:U6 snRNA-specific terminal uridylyltransferase 1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Mellman et al. (2008)	pubmed:18288197|doi:10.1038/nature06666|imex:IM-22001	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15687354|imex:IM-22001-1|dip:DIP-195766E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001129108.1|refseq:NP_001129109.1|refseq:NP_001129110.1|refseq:NP_003548.1|refseq:NP_001317618.1|ensembl:ENSG00000143398(gene)|ensembl:ENST00000368888(transcript)|go:"GO:0000285"(1-phosphatidylinositol-3-phosphate 5-kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006650"(glycerophospholipid metabolic process)|go:"GO:0006661"(phosphatidylinositol biosynthetic process)|go:"GO:0006909"(phagocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0008654"(phospholipid biosynthetic process)|go:"GO:0010761"(fibroblast migration)|go:"GO:0014066"(regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016308"(1-phosphatidylinositol-4-phosphate 5-kinase activity)|go:"GO:0016477"(cell migration)|go:"GO:0016607"(nuclear speck)|go:"GO:0019900"(kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0032587"(ruffle membrane)|go:"GO:0048041"(focal adhesion assembly)|go:"GO:0052810"(1-phosphatidylinositol-5-kinase activity)|go:"GO:0052812"(phosphatidylinositol-3,4-bisphosphate 5-kinase activity)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:0097178"(ruffle assembly)|interpro:IPR002498(Phosphatidylinositol-4-phosphate 5-kinase, core)|interpro:IPR023610|interpro:IPR027484|reactome:R-HSA-1660499|reactome:R-HSA-6811558|dip:DIP-60649N	rcsb pdb:5WU6|rcsb pdb:5WU5|ensembl:ENSG00000149016(gene)|ensembl:ENST00000476907(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0004652"(polynucleotide adenylyltransferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0016180"(snRNA processing)|go:"GO:0016607"(nuclear speck)|go:"GO:0016779"(nucleotidyltransferase activity)|go:"GO:0017070"(U6 snRNA binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0031123"(RNA 3'-end processing)|go:"GO:0034477"(U6 snRNA 3'-end processing)|go:"GO:0046872"(metal ion binding)|go:"GO:0050265"(RNA uridylyltransferase activity)|go:"GO:0098789"(pre-mRNA cleavage required for polyadenylation)|go:"GO:1990817"(RNA adenylyltransferase activity)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002058(PAP/25A-associated)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034388|interpro:IPR035979|interpro:IPR036236|interpro:IPR043519|mint:Q9H6E5|rcsb pdb:2E5G|rcsb pdb:5WU1|rcsb pdb:5WU2|rcsb pdb:5WU3|rcsb pdb:5WU4|go:"GO:0005730"(nucleolus)|refseq:NP_073741.2|dip:DIP-53651N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2017/08/05	2017/08/10	rogid:jDE/jXrUlbohCr2mZjEgIxTVzjU9606	rogid:7Df5H4dyiKBTRo4xiRZGbzGvzbk9606	rigid:Fy0GIgsluxLgdwf1HqTf5f2hORU	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q92797	uniprotkb:Q9H6E5	intact:EBI-1051992|uniprotkb:O00521|uniprotkb:O00689|uniprotkb:O00733|uniprotkb:Q59GT5|uniprotkb:Q8N2U5|ensembl:ENSP00000245934	intact:EBI-2511680|ensembl:ENSP00000419607|uniprotkb:Q9H6H7|uniprotkb:Q7L583|uniprotkb:Q2NL65|uniprotkb:A1A527|intact:EBI-2809257|uniprotkb:A8K995	psi-mi:sympk_human(display_long)|uniprotkb:SYMPK(gene name)|psi-mi:SYMPK(display_short)|uniprotkb:SPK(gene name synonym)	psi-mi:stpap_human(display_long)|uniprotkb:TUT1(gene name)|psi-mi:TUT1(display_short)|uniprotkb:RBM21(gene name synonym)|uniprotkb:RNA-binding motif protein 21(gene name synonym)|uniprotkb:U6 snRNA-specific terminal uridylyltransferase 1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Mellman et al. (2008)	pubmed:18288197|doi:10.1038/nature06666|imex:IM-22001	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15687371|imex:IM-22001-2|dip:DIP-195764E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0016604"(nuclear body)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0035307"(positive regulation of protein dephosphorylation)|go:"GO:0097165"(nuclear stress granule)|ensembl:ENSG00000125755(gene)|ensembl:ENST00000245934(transcript)|interpro:IPR011989(Armadillo-like helical)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021850|interpro:IPR022075|interpro:IPR032460|mint:Q92797|rcsb pdb:3O2Q|rcsb pdb:3O2S|rcsb pdb:3O2T|rcsb pdb:3ODR|go:"GO:0005829"(cytosol)|go:"GO:0005847"(mRNA cleavage and polyadenylation specificity factor complex)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0007155"(cell adhesion)|refseq:NP_004810.2|refseq:XP_011525656.1|refseq:XP_005259343.1|dip:DIP-42506N|rcsb pdb:3ODS|rcsb pdb:4H3H|rcsb pdb:4H3K|rcsb pdb:6V4X|reactome:R-HSA-159231|reactome:R-HSA-72163|reactome:R-HSA-72187|reactome:R-HSA-73856|reactome:R-HSA-77595	rcsb pdb:5WU6|rcsb pdb:5WU5|ensembl:ENSG00000149016(gene)|ensembl:ENST00000476907(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0004652"(polynucleotide adenylyltransferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0016180"(snRNA processing)|go:"GO:0016607"(nuclear speck)|go:"GO:0016779"(nucleotidyltransferase activity)|go:"GO:0017070"(U6 snRNA binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0031123"(RNA 3'-end processing)|go:"GO:0034477"(U6 snRNA 3'-end processing)|go:"GO:0046872"(metal ion binding)|go:"GO:0050265"(RNA uridylyltransferase activity)|go:"GO:0098789"(pre-mRNA cleavage required for polyadenylation)|go:"GO:1990817"(RNA adenylyltransferase activity)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002058(PAP/25A-associated)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034388|interpro:IPR035979|interpro:IPR036236|interpro:IPR043519|mint:Q9H6E5|rcsb pdb:2E5G|rcsb pdb:5WU1|rcsb pdb:5WU2|rcsb pdb:5WU3|rcsb pdb:5WU4|go:"GO:0005730"(nucleolus)|refseq:NP_073741.2|dip:DIP-53651N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2017/08/05	2017/08/10	rogid:+svYKfmD5gCiOxf9FxGUZKCNhtQ9606	rogid:7Df5H4dyiKBTRo4xiRZGbzGvzbk9606	rigid:jaGx5RwWpAeDq8YGlcDUFBQblfI	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q92797	uniprotkb:Q9P2I0	intact:EBI-1051992|uniprotkb:O00521|uniprotkb:O00689|uniprotkb:O00733|uniprotkb:Q59GT5|uniprotkb:Q8N2U5|ensembl:ENSP00000245934	intact:EBI-1043224|uniprotkb:Q6NSJ1|uniprotkb:Q9H3W7|ensembl:ENSP00000298875|uniprotkb:B3KME1	psi-mi:sympk_human(display_long)|uniprotkb:SYMPK(gene name)|psi-mi:SYMPK(display_short)|uniprotkb:SPK(gene name synonym)	psi-mi:cpsf2_human(display_long)|uniprotkb:Cleavage and polyadenylation specificity factor 100 kDa subunit(gene name synonym)|uniprotkb:CPSF2(gene name)|psi-mi:CPSF2(display_short)|uniprotkb:CPSF100(gene name synonym)|uniprotkb:KIAA1367(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Mellman et al. (2008)	pubmed:18288197|doi:10.1038/nature06666|imex:IM-22001	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15687371|imex:IM-22001-2|dip:DIP-195764E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0016604"(nuclear body)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0035307"(positive regulation of protein dephosphorylation)|go:"GO:0097165"(nuclear stress granule)|ensembl:ENSG00000125755(gene)|ensembl:ENST00000245934(transcript)|interpro:IPR011989(Armadillo-like helical)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021850|interpro:IPR022075|interpro:IPR032460|mint:Q92797|rcsb pdb:3O2Q|rcsb pdb:3O2S|rcsb pdb:3O2T|rcsb pdb:3ODR|go:"GO:0005829"(cytosol)|go:"GO:0005847"(mRNA cleavage and polyadenylation specificity factor complex)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0007155"(cell adhesion)|refseq:NP_004810.2|refseq:XP_011525656.1|refseq:XP_005259343.1|dip:DIP-42506N|rcsb pdb:3ODS|rcsb pdb:4H3H|rcsb pdb:4H3K|rcsb pdb:6V4X|reactome:R-HSA-159231|reactome:R-HSA-72163|reactome:R-HSA-72187|reactome:R-HSA-73856|reactome:R-HSA-77595	interpro:IPR001279(Beta-lactamase-like)|interpro:IPR011108(RNA-metabolising metallo-beta-lactamase)|interpro:IPR022712|interpro:IPR025069|interpro:IPR027075|interpro:IPR035639|interpro:IPR036866|mint:Q9P2I0|rcsb pdb:6URG|rcsb pdb:6V4X|reactome:R-HSA-159231|reactome:R-HSA-72163|reactome:R-HSA-72187|reactome:R-HSA-73856|reactome:R-HSA-77595|go:"GO:0098789"(pre-mRNA cleavage required for polyadenylation)|ensembl:ENSG00000165934(gene)|ensembl:ENST00000298875(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005847"(mRNA cleavage and polyadenylation specificity factor complex)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0006398"(mRNA 3'-end processing by stem-loop binding and cleavage)|go:"GO:0016020"(membrane)|refseq:NP_059133.1|refseq:NP_001309201.1|dip:DIP-42500N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2017/08/05	2017/08/10	rogid:+svYKfmD5gCiOxf9FxGUZKCNhtQ9606	rogid:RYiaQ8q9VM7htGre4S8PkSQaCz89606	rigid:jaGx5RwWpAeDq8YGlcDUFBQblfI	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q99755-1	uniprotkb:Q9H6E5	intact:EBI-15687389|ensembl:ENSP00000357883	intact:EBI-2511680|ensembl:ENSP00000419607|uniprotkb:Q9H6H7|uniprotkb:Q7L583|uniprotkb:Q2NL65|uniprotkb:A1A527|intact:EBI-2809257|uniprotkb:A8K995	psi-mi:q99755-1(display_long)|uniprotkb:PIP5K1A(gene name)|psi-mi:PIP5K1A(display_short)|uniprotkb:68 kDa type I phosphatidylinositol 4-phosphate 5-kinase alpha(gene name synonym)|uniprotkb:Phosphatidylinositol 4-phosphate 5-kinase type I alpha(gene name synonym)|uniprotkb:PIP5KIalpha2(isoform synonym)	psi-mi:stpap_human(display_long)|uniprotkb:TUT1(gene name)|psi-mi:TUT1(display_short)|uniprotkb:RBM21(gene name synonym)|uniprotkb:RNA-binding motif protein 21(gene name synonym)|uniprotkb:U6 snRNA-specific terminal uridylyltransferase 1(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Mellman et al. (2008)	pubmed:18288197|doi:10.1038/nature06666|imex:IM-22001	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15687397|imex:IM-22001-3|dip:DIP-195766E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000143398(gene)|ensembl:ENST00000368888(transcript)|intact:EBI-726414(isoform-parent)	rcsb pdb:5WU6|rcsb pdb:5WU5|ensembl:ENSG00000149016(gene)|ensembl:ENST00000476907(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0004652"(polynucleotide adenylyltransferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0016180"(snRNA processing)|go:"GO:0016607"(nuclear speck)|go:"GO:0016779"(nucleotidyltransferase activity)|go:"GO:0017070"(U6 snRNA binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0031123"(RNA 3'-end processing)|go:"GO:0034477"(U6 snRNA 3'-end processing)|go:"GO:0046872"(metal ion binding)|go:"GO:0050265"(RNA uridylyltransferase activity)|go:"GO:0098789"(pre-mRNA cleavage required for polyadenylation)|go:"GO:1990817"(RNA adenylyltransferase activity)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002058(PAP/25A-associated)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034388|interpro:IPR035979|interpro:IPR036236|interpro:IPR043519|mint:Q9H6E5|rcsb pdb:2E5G|rcsb pdb:5WU1|rcsb pdb:5WU2|rcsb pdb:5WU3|rcsb pdb:5WU4|go:"GO:0005730"(nucleolus)|refseq:NP_073741.2|dip:DIP-53651N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2017/08/05	2017/08/10	rogid:jDE/jXrUlbohCr2mZjEgIxTVzjU9606	rogid:7Df5H4dyiKBTRo4xiRZGbzGvzbk9606	rigid:Fy0GIgsluxLgdwf1HqTf5f2hORU	false	sufficient binding region:440-562	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P51003	uniprotkb:Q9UKF6	intact:EBI-359376|uniprotkb:Q86SX4|uniprotkb:Q86TV0|uniprotkb:Q8IYF5|uniprotkb:Q9BVU2|ensembl:ENSP00000216277	intact:EBI-1044699|uniprotkb:O14769|uniprotkb:Q96F36|uniprotkb:Q53RS2|ensembl:ENSP00000238112	psi-mi:papoa_human(display_long)|uniprotkb:PAPOLA(gene name)|psi-mi:PAPOLA(display_short)|uniprotkb:PAP(gene name synonym)|uniprotkb:Polynucleotide adenylyltransferase alpha(gene name synonym)	psi-mi:cpsf3_human(display_long)|uniprotkb:Cleavage and polyadenylation specificity factor 73 kDa subunit(gene name synonym)|uniprotkb:mRNA 3'-end-processing endonuclease CPSF-73(gene name synonym)|uniprotkb:CPSF3(gene name)|psi-mi:CPSF3(display_short)|uniprotkb:CPSF73(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Mellman et al. (2008)	pubmed:18288197|doi:10.1038/nature06666|imex:IM-22001	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15687416|imex:IM-22001-4|dip:DIP-195768E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_116021.2|refseq:NP_001238935.1|refseq:NP_001238936.1|ensembl:ENSG00000090060(gene)|ensembl:ENST00000216277(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004652"(polynucleotide adenylyltransferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0030145"(manganese ion binding)|go:"GO:0031124"(mRNA 3'-end processing)|go:"GO:0031440"(regulation of mRNA 3'-end processing)|go:"GO:0043631"(RNA polyadenylation)|interpro:IPR002934(Nucleotidyltransferase)|interpro:IPR007010("Poly(A) polymerase, RNA-binding region")|interpro:IPR007012("Poly(A) polymerase, central region")|interpro:IPR011068(Nucleotidyltransferase, class I, C-terminal-like)|interpro:IPR014492("Poly(A) polymerase")|interpro:IPR043519|mint:P51003|reactome:R-HSA-72163|reactome:R-HSA-72187|reactome:R-HSA-73856|reactome:R-HSA-77595|refseq:NP_001280556.1|refseq:NP_001280557.1|refseq:NP_001280561.1|dip:DIP-27610N|dip:DIP-40865N	refseq:NP_057291.1|ensembl:ENSG00000119203(gene)|ensembl:ENST00000238112(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004521"(endoribonuclease activity)|go:"GO:0004534"(5'-3' exoribonuclease activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005847"(mRNA cleavage and polyadenylation specificity factor complex)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0006379"(mRNA cleavage)|go:"GO:0006398"(mRNA 3'-end processing by stem-loop binding and cleavage)|interpro:IPR021718|interpro:IPR022712|interpro:IPR036866|mint:Q9UKF6|rcsb pdb:2I7T|rcsb pdb:2I7V|rcsb pdb:6M8Q|rcsb pdb:6V4X|reactome:R-HSA-159231|reactome:R-HSA-72163|reactome:R-HSA-72187|reactome:R-HSA-73856|reactome:R-HSA-77595|go:"GO:0008409"(5'-3' exonuclease activity)|go:"GO:0046872"(metal ion binding)|interpro:IPR001279(Beta-lactamase-like)|interpro:IPR011108(RNA-metabolising metallo-beta-lactamase)|dip:DIP-42501N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2017/08/05	2017/08/10	rogid:rRMBZRE1yFjnO+pnz5g4k+u7hwo9606	rogid:lpTAUhlcFjFt2tHErN9igCjWTzs9606	rigid:krGmfAqhxHeMAjon0HkFyoprtqw	false	flag tag:n-n	-	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:P51003	uniprotkb:Q92797	intact:EBI-359376|uniprotkb:Q86SX4|uniprotkb:Q86TV0|uniprotkb:Q8IYF5|uniprotkb:Q9BVU2|ensembl:ENSP00000216277	intact:EBI-1051992|uniprotkb:O00521|uniprotkb:O00689|uniprotkb:O00733|uniprotkb:Q59GT5|uniprotkb:Q8N2U5|ensembl:ENSP00000245934	psi-mi:papoa_human(display_long)|uniprotkb:PAPOLA(gene name)|psi-mi:PAPOLA(display_short)|uniprotkb:PAP(gene name synonym)|uniprotkb:Polynucleotide adenylyltransferase alpha(gene name synonym)	psi-mi:sympk_human(display_long)|uniprotkb:SYMPK(gene name)|psi-mi:SYMPK(display_short)|uniprotkb:SPK(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Mellman et al. (2008)	pubmed:18288197|doi:10.1038/nature06666|imex:IM-22001	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15687416|imex:IM-22001-4|dip:DIP-195768E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_116021.2|refseq:NP_001238935.1|refseq:NP_001238936.1|ensembl:ENSG00000090060(gene)|ensembl:ENST00000216277(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004652"(polynucleotide adenylyltransferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0030145"(manganese ion binding)|go:"GO:0031124"(mRNA 3'-end processing)|go:"GO:0031440"(regulation of mRNA 3'-end processing)|go:"GO:0043631"(RNA polyadenylation)|interpro:IPR002934(Nucleotidyltransferase)|interpro:IPR007010("Poly(A) polymerase, RNA-binding region")|interpro:IPR007012("Poly(A) polymerase, central region")|interpro:IPR011068(Nucleotidyltransferase, class I, C-terminal-like)|interpro:IPR014492("Poly(A) polymerase")|interpro:IPR043519|mint:P51003|reactome:R-HSA-72163|reactome:R-HSA-72187|reactome:R-HSA-73856|reactome:R-HSA-77595|refseq:NP_001280556.1|refseq:NP_001280557.1|refseq:NP_001280561.1|dip:DIP-27610N|dip:DIP-40865N	go:"GO:0016604"(nuclear body)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0035307"(positive regulation of protein dephosphorylation)|go:"GO:0097165"(nuclear stress granule)|ensembl:ENSG00000125755(gene)|ensembl:ENST00000245934(transcript)|interpro:IPR011989(Armadillo-like helical)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021850|interpro:IPR022075|interpro:IPR032460|mint:Q92797|rcsb pdb:3O2Q|rcsb pdb:3O2S|rcsb pdb:3O2T|rcsb pdb:3ODR|go:"GO:0005829"(cytosol)|go:"GO:0005847"(mRNA cleavage and polyadenylation specificity factor complex)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0007155"(cell adhesion)|refseq:NP_004810.2|refseq:XP_011525656.1|refseq:XP_005259343.1|dip:DIP-42506N|rcsb pdb:3ODS|rcsb pdb:4H3H|rcsb pdb:4H3K|rcsb pdb:6V4X|reactome:R-HSA-159231|reactome:R-HSA-72163|reactome:R-HSA-72187|reactome:R-HSA-73856|reactome:R-HSA-77595	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2017/08/05	2017/08/10	rogid:rRMBZRE1yFjnO+pnz5g4k+u7hwo9606	rogid:+svYKfmD5gCiOxf9FxGUZKCNhtQ9606	rigid:krGmfAqhxHeMAjon0HkFyoprtqw	false	flag tag:n-n	-	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:P51003	uniprotkb:Q9P2I0	intact:EBI-359376|uniprotkb:Q86SX4|uniprotkb:Q86TV0|uniprotkb:Q8IYF5|uniprotkb:Q9BVU2|ensembl:ENSP00000216277	intact:EBI-1043224|uniprotkb:Q6NSJ1|uniprotkb:Q9H3W7|ensembl:ENSP00000298875|uniprotkb:B3KME1	psi-mi:papoa_human(display_long)|uniprotkb:PAPOLA(gene name)|psi-mi:PAPOLA(display_short)|uniprotkb:PAP(gene name synonym)|uniprotkb:Polynucleotide adenylyltransferase alpha(gene name synonym)	psi-mi:cpsf2_human(display_long)|uniprotkb:Cleavage and polyadenylation specificity factor 100 kDa subunit(gene name synonym)|uniprotkb:CPSF2(gene name)|psi-mi:CPSF2(display_short)|uniprotkb:CPSF100(gene name synonym)|uniprotkb:KIAA1367(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Mellman et al. (2008)	pubmed:18288197|doi:10.1038/nature06666|imex:IM-22001	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15687416|imex:IM-22001-4|dip:DIP-195768E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_116021.2|refseq:NP_001238935.1|refseq:NP_001238936.1|ensembl:ENSG00000090060(gene)|ensembl:ENST00000216277(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004652"(polynucleotide adenylyltransferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0030145"(manganese ion binding)|go:"GO:0031124"(mRNA 3'-end processing)|go:"GO:0031440"(regulation of mRNA 3'-end processing)|go:"GO:0043631"(RNA polyadenylation)|interpro:IPR002934(Nucleotidyltransferase)|interpro:IPR007010("Poly(A) polymerase, RNA-binding region")|interpro:IPR007012("Poly(A) polymerase, central region")|interpro:IPR011068(Nucleotidyltransferase, class I, C-terminal-like)|interpro:IPR014492("Poly(A) polymerase")|interpro:IPR043519|mint:P51003|reactome:R-HSA-72163|reactome:R-HSA-72187|reactome:R-HSA-73856|reactome:R-HSA-77595|refseq:NP_001280556.1|refseq:NP_001280557.1|refseq:NP_001280561.1|dip:DIP-27610N|dip:DIP-40865N	interpro:IPR001279(Beta-lactamase-like)|interpro:IPR011108(RNA-metabolising metallo-beta-lactamase)|interpro:IPR022712|interpro:IPR025069|interpro:IPR027075|interpro:IPR035639|interpro:IPR036866|mint:Q9P2I0|rcsb pdb:6URG|rcsb pdb:6V4X|reactome:R-HSA-159231|reactome:R-HSA-72163|reactome:R-HSA-72187|reactome:R-HSA-73856|reactome:R-HSA-77595|go:"GO:0098789"(pre-mRNA cleavage required for polyadenylation)|ensembl:ENSG00000165934(gene)|ensembl:ENST00000298875(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005847"(mRNA cleavage and polyadenylation specificity factor complex)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0006398"(mRNA 3'-end processing by stem-loop binding and cleavage)|go:"GO:0016020"(membrane)|refseq:NP_059133.1|refseq:NP_001309201.1|dip:DIP-42500N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2017/08/05	2017/08/10	rogid:rRMBZRE1yFjnO+pnz5g4k+u7hwo9606	rogid:RYiaQ8q9VM7htGre4S8PkSQaCz89606	rigid:krGmfAqhxHeMAjon0HkFyoprtqw	false	flag tag:n-n	-	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q99755-1	uniprotkb:Q9H6E5	intact:EBI-15687389|ensembl:ENSP00000357883	intact:EBI-2511680|ensembl:ENSP00000419607|uniprotkb:Q9H6H7|uniprotkb:Q7L583|uniprotkb:Q2NL65|uniprotkb:A1A527|intact:EBI-2809257|uniprotkb:A8K995	psi-mi:q99755-1(display_long)|uniprotkb:PIP5K1A(gene name)|psi-mi:PIP5K1A(display_short)|uniprotkb:68 kDa type I phosphatidylinositol 4-phosphate 5-kinase alpha(gene name synonym)|uniprotkb:Phosphatidylinositol 4-phosphate 5-kinase type I alpha(gene name synonym)|uniprotkb:PIP5KIalpha2(isoform synonym)	psi-mi:stpap_human(display_long)|uniprotkb:TUT1(gene name)|psi-mi:TUT1(display_short)|uniprotkb:RBM21(gene name synonym)|uniprotkb:RNA-binding motif protein 21(gene name synonym)|uniprotkb:U6 snRNA-specific terminal uridylyltransferase 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Mellman et al. (2008)	pubmed:18288197|doi:10.1038/nature06666|imex:IM-22001	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15687460|imex:IM-22001-6|dip:DIP-195766E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000143398(gene)|ensembl:ENST00000368888(transcript)|intact:EBI-726414(isoform-parent)	rcsb pdb:5WU6|rcsb pdb:5WU5|ensembl:ENSG00000149016(gene)|ensembl:ENST00000476907(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0004652"(polynucleotide adenylyltransferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0016180"(snRNA processing)|go:"GO:0016607"(nuclear speck)|go:"GO:0016779"(nucleotidyltransferase activity)|go:"GO:0017070"(U6 snRNA binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0031123"(RNA 3'-end processing)|go:"GO:0034477"(U6 snRNA 3'-end processing)|go:"GO:0046872"(metal ion binding)|go:"GO:0050265"(RNA uridylyltransferase activity)|go:"GO:0098789"(pre-mRNA cleavage required for polyadenylation)|go:"GO:1990817"(RNA adenylyltransferase activity)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002058(PAP/25A-associated)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034388|interpro:IPR035979|interpro:IPR036236|interpro:IPR043519|mint:Q9H6E5|rcsb pdb:2E5G|rcsb pdb:5WU1|rcsb pdb:5WU2|rcsb pdb:5WU3|rcsb pdb:5WU4|go:"GO:0005730"(nucleolus)|refseq:NP_073741.2|dip:DIP-53651N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/05	2017/08/10	rogid:jDE/jXrUlbohCr2mZjEgIxTVzjU9606	rogid:7Df5H4dyiKBTRo4xiRZGbzGvzbk9606	rigid:Fy0GIgsluxLgdwf1HqTf5f2hORU	false	sufficient binding region:440-562|glutathione s tranferase tag:?-?	his tag:n-n	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9H6E5	uniprotkb:P33240	intact:EBI-2511680|ensembl:ENSP00000419607|uniprotkb:Q9H6H7|uniprotkb:Q7L583|uniprotkb:Q2NL65|uniprotkb:A1A527|intact:EBI-2809257|uniprotkb:A8K995	intact:EBI-711360|uniprotkb:Q5H951|uniprotkb:Q6LA74|uniprotkb:Q8N502|ensembl:ENSP00000362063	psi-mi:stpap_human(display_long)|uniprotkb:TUT1(gene name)|psi-mi:TUT1(display_short)|uniprotkb:RBM21(gene name synonym)|uniprotkb:RNA-binding motif protein 21(gene name synonym)|uniprotkb:U6 snRNA-specific terminal uridylyltransferase 1(gene name synonym)	psi-mi:cstf2_human(display_long)|uniprotkb:CSTF2(gene name)|psi-mi:CSTF2(display_short)|uniprotkb:CF-1 64 kDa subunit(gene name synonym)|uniprotkb:Cleavage stimulation factor 64 kDa subunit(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Mellman et al. (2008)	pubmed:18288197|doi:10.1038/nature06666|imex:IM-22001	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15687437|imex:IM-22001-5|dip:DIP-195767E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rcsb pdb:5WU6|rcsb pdb:5WU5|ensembl:ENSG00000149016(gene)|ensembl:ENST00000476907(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0004652"(polynucleotide adenylyltransferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0016180"(snRNA processing)|go:"GO:0016607"(nuclear speck)|go:"GO:0016779"(nucleotidyltransferase activity)|go:"GO:0017070"(U6 snRNA binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0031123"(RNA 3'-end processing)|go:"GO:0034477"(U6 snRNA 3'-end processing)|go:"GO:0046872"(metal ion binding)|go:"GO:0050265"(RNA uridylyltransferase activity)|go:"GO:0098789"(pre-mRNA cleavage required for polyadenylation)|go:"GO:1990817"(RNA adenylyltransferase activity)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002058(PAP/25A-associated)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034388|interpro:IPR035979|interpro:IPR036236|interpro:IPR043519|mint:Q9H6E5|rcsb pdb:2E5G|rcsb pdb:5WU1|rcsb pdb:5WU2|rcsb pdb:5WU3|rcsb pdb:5WU4|go:"GO:0005730"(nucleolus)|refseq:NP_073741.2|dip:DIP-53651N	refseq:NP_001293138.1|ensembl:ENSG00000101811(gene)|ensembl:ENST00000372972(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005847"(mRNA cleavage and polyadenylation specificity factor complex)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0016604"(nuclear body)|go:"GO:0071920"(cleavage body)|go:"GO:0098789"(pre-mRNA cleavage required for polyadenylation)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR025742|interpro:IPR026896|interpro:IPR033105|interpro:IPR035979|interpro:IPR038192|mint:P33240|rcsb pdb:1P1T|rcsb pdb:2J8P|rcsb pdb:6Q2I|rcsb pdb:6TZE|reactome:R-HSA-6784531|reactome:R-HSA-72163|reactome:R-HSA-72187|reactome:R-HSA-73856|reactome:R-HSA-77595|refseq:NP_001316.1|dip:DIP-36129N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2017/08/05	2017/08/10	rogid:7Df5H4dyiKBTRo4xiRZGbzGvzbk9606	rogid:oZ/4DPJOEWflU05127TEp+ezQi89606	rigid:WLhB6kKvejsSlmVe3NktbOulAXU	false	flag tag:n-n	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9H6E5	uniprotkb:Q9UKF6	intact:EBI-2511680|ensembl:ENSP00000419607|uniprotkb:Q9H6H7|uniprotkb:Q7L583|uniprotkb:Q2NL65|uniprotkb:A1A527|intact:EBI-2809257|uniprotkb:A8K995	intact:EBI-1044699|uniprotkb:O14769|uniprotkb:Q96F36|uniprotkb:Q53RS2|ensembl:ENSP00000238112	psi-mi:stpap_human(display_long)|uniprotkb:TUT1(gene name)|psi-mi:TUT1(display_short)|uniprotkb:RBM21(gene name synonym)|uniprotkb:RNA-binding motif protein 21(gene name synonym)|uniprotkb:U6 snRNA-specific terminal uridylyltransferase 1(gene name synonym)	psi-mi:cpsf3_human(display_long)|uniprotkb:Cleavage and polyadenylation specificity factor 73 kDa subunit(gene name synonym)|uniprotkb:mRNA 3'-end-processing endonuclease CPSF-73(gene name synonym)|uniprotkb:CPSF3(gene name)|psi-mi:CPSF3(display_short)|uniprotkb:CPSF73(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Mellman et al. (2008)	pubmed:18288197|doi:10.1038/nature06666|imex:IM-22001	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15687437|imex:IM-22001-5|dip:DIP-195767E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rcsb pdb:5WU6|rcsb pdb:5WU5|ensembl:ENSG00000149016(gene)|ensembl:ENST00000476907(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0004652"(polynucleotide adenylyltransferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0016180"(snRNA processing)|go:"GO:0016607"(nuclear speck)|go:"GO:0016779"(nucleotidyltransferase activity)|go:"GO:0017070"(U6 snRNA binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0031123"(RNA 3'-end processing)|go:"GO:0034477"(U6 snRNA 3'-end processing)|go:"GO:0046872"(metal ion binding)|go:"GO:0050265"(RNA uridylyltransferase activity)|go:"GO:0098789"(pre-mRNA cleavage required for polyadenylation)|go:"GO:1990817"(RNA adenylyltransferase activity)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002058(PAP/25A-associated)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034388|interpro:IPR035979|interpro:IPR036236|interpro:IPR043519|mint:Q9H6E5|rcsb pdb:2E5G|rcsb pdb:5WU1|rcsb pdb:5WU2|rcsb pdb:5WU3|rcsb pdb:5WU4|go:"GO:0005730"(nucleolus)|refseq:NP_073741.2|dip:DIP-53651N	refseq:NP_057291.1|ensembl:ENSG00000119203(gene)|ensembl:ENST00000238112(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004521"(endoribonuclease activity)|go:"GO:0004534"(5'-3' exoribonuclease activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005847"(mRNA cleavage and polyadenylation specificity factor complex)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0006379"(mRNA cleavage)|go:"GO:0006398"(mRNA 3'-end processing by stem-loop binding and cleavage)|interpro:IPR021718|interpro:IPR022712|interpro:IPR036866|mint:Q9UKF6|rcsb pdb:2I7T|rcsb pdb:2I7V|rcsb pdb:6M8Q|rcsb pdb:6V4X|reactome:R-HSA-159231|reactome:R-HSA-72163|reactome:R-HSA-72187|reactome:R-HSA-73856|reactome:R-HSA-77595|go:"GO:0008409"(5'-3' exonuclease activity)|go:"GO:0046872"(metal ion binding)|interpro:IPR001279(Beta-lactamase-like)|interpro:IPR011108(RNA-metabolising metallo-beta-lactamase)|dip:DIP-42501N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2017/08/05	2017/08/10	rogid:7Df5H4dyiKBTRo4xiRZGbzGvzbk9606	rogid:lpTAUhlcFjFt2tHErN9igCjWTzs9606	rigid:WLhB6kKvejsSlmVe3NktbOulAXU	false	flag tag:n-n	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9H6E5	uniprotkb:Q92797	intact:EBI-2511680|ensembl:ENSP00000419607|uniprotkb:Q9H6H7|uniprotkb:Q7L583|uniprotkb:Q2NL65|uniprotkb:A1A527|intact:EBI-2809257|uniprotkb:A8K995	intact:EBI-1051992|uniprotkb:O00521|uniprotkb:O00689|uniprotkb:O00733|uniprotkb:Q59GT5|uniprotkb:Q8N2U5|ensembl:ENSP00000245934	psi-mi:stpap_human(display_long)|uniprotkb:TUT1(gene name)|psi-mi:TUT1(display_short)|uniprotkb:RBM21(gene name synonym)|uniprotkb:RNA-binding motif protein 21(gene name synonym)|uniprotkb:U6 snRNA-specific terminal uridylyltransferase 1(gene name synonym)	psi-mi:sympk_human(display_long)|uniprotkb:SYMPK(gene name)|psi-mi:SYMPK(display_short)|uniprotkb:SPK(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Mellman et al. (2008)	pubmed:18288197|doi:10.1038/nature06666|imex:IM-22001	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15687437|imex:IM-22001-5|dip:DIP-195767E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rcsb pdb:5WU6|rcsb pdb:5WU5|ensembl:ENSG00000149016(gene)|ensembl:ENST00000476907(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0004652"(polynucleotide adenylyltransferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0016180"(snRNA processing)|go:"GO:0016607"(nuclear speck)|go:"GO:0016779"(nucleotidyltransferase activity)|go:"GO:0017070"(U6 snRNA binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0031123"(RNA 3'-end processing)|go:"GO:0034477"(U6 snRNA 3'-end processing)|go:"GO:0046872"(metal ion binding)|go:"GO:0050265"(RNA uridylyltransferase activity)|go:"GO:0098789"(pre-mRNA cleavage required for polyadenylation)|go:"GO:1990817"(RNA adenylyltransferase activity)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002058(PAP/25A-associated)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034388|interpro:IPR035979|interpro:IPR036236|interpro:IPR043519|mint:Q9H6E5|rcsb pdb:2E5G|rcsb pdb:5WU1|rcsb pdb:5WU2|rcsb pdb:5WU3|rcsb pdb:5WU4|go:"GO:0005730"(nucleolus)|refseq:NP_073741.2|dip:DIP-53651N	go:"GO:0016604"(nuclear body)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0035307"(positive regulation of protein dephosphorylation)|go:"GO:0097165"(nuclear stress granule)|ensembl:ENSG00000125755(gene)|ensembl:ENST00000245934(transcript)|interpro:IPR011989(Armadillo-like helical)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021850|interpro:IPR022075|interpro:IPR032460|mint:Q92797|rcsb pdb:3O2Q|rcsb pdb:3O2S|rcsb pdb:3O2T|rcsb pdb:3ODR|go:"GO:0005829"(cytosol)|go:"GO:0005847"(mRNA cleavage and polyadenylation specificity factor complex)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0007155"(cell adhesion)|refseq:NP_004810.2|refseq:XP_011525656.1|refseq:XP_005259343.1|dip:DIP-42506N|rcsb pdb:3ODS|rcsb pdb:4H3H|rcsb pdb:4H3K|rcsb pdb:6V4X|reactome:R-HSA-159231|reactome:R-HSA-72163|reactome:R-HSA-72187|reactome:R-HSA-73856|reactome:R-HSA-77595	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2017/08/05	2017/08/10	rogid:7Df5H4dyiKBTRo4xiRZGbzGvzbk9606	rogid:+svYKfmD5gCiOxf9FxGUZKCNhtQ9606	rigid:WLhB6kKvejsSlmVe3NktbOulAXU	false	flag tag:n-n	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9H6E5	uniprotkb:Q9P2I0	intact:EBI-2511680|ensembl:ENSP00000419607|uniprotkb:Q9H6H7|uniprotkb:Q7L583|uniprotkb:Q2NL65|uniprotkb:A1A527|intact:EBI-2809257|uniprotkb:A8K995	intact:EBI-1043224|uniprotkb:Q6NSJ1|uniprotkb:Q9H3W7|ensembl:ENSP00000298875|uniprotkb:B3KME1	psi-mi:stpap_human(display_long)|uniprotkb:TUT1(gene name)|psi-mi:TUT1(display_short)|uniprotkb:RBM21(gene name synonym)|uniprotkb:RNA-binding motif protein 21(gene name synonym)|uniprotkb:U6 snRNA-specific terminal uridylyltransferase 1(gene name synonym)	psi-mi:cpsf2_human(display_long)|uniprotkb:Cleavage and polyadenylation specificity factor 100 kDa subunit(gene name synonym)|uniprotkb:CPSF2(gene name)|psi-mi:CPSF2(display_short)|uniprotkb:CPSF100(gene name synonym)|uniprotkb:KIAA1367(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Mellman et al. (2008)	pubmed:18288197|doi:10.1038/nature06666|imex:IM-22001	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15687437|imex:IM-22001-5|dip:DIP-195767E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rcsb pdb:5WU6|rcsb pdb:5WU5|ensembl:ENSG00000149016(gene)|ensembl:ENST00000476907(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0004652"(polynucleotide adenylyltransferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0016180"(snRNA processing)|go:"GO:0016607"(nuclear speck)|go:"GO:0016779"(nucleotidyltransferase activity)|go:"GO:0017070"(U6 snRNA binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0031123"(RNA 3'-end processing)|go:"GO:0034477"(U6 snRNA 3'-end processing)|go:"GO:0046872"(metal ion binding)|go:"GO:0050265"(RNA uridylyltransferase activity)|go:"GO:0098789"(pre-mRNA cleavage required for polyadenylation)|go:"GO:1990817"(RNA adenylyltransferase activity)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002058(PAP/25A-associated)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034388|interpro:IPR035979|interpro:IPR036236|interpro:IPR043519|mint:Q9H6E5|rcsb pdb:2E5G|rcsb pdb:5WU1|rcsb pdb:5WU2|rcsb pdb:5WU3|rcsb pdb:5WU4|go:"GO:0005730"(nucleolus)|refseq:NP_073741.2|dip:DIP-53651N	interpro:IPR001279(Beta-lactamase-like)|interpro:IPR011108(RNA-metabolising metallo-beta-lactamase)|interpro:IPR022712|interpro:IPR025069|interpro:IPR027075|interpro:IPR035639|interpro:IPR036866|mint:Q9P2I0|rcsb pdb:6URG|rcsb pdb:6V4X|reactome:R-HSA-159231|reactome:R-HSA-72163|reactome:R-HSA-72187|reactome:R-HSA-73856|reactome:R-HSA-77595|go:"GO:0098789"(pre-mRNA cleavage required for polyadenylation)|ensembl:ENSG00000165934(gene)|ensembl:ENST00000298875(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005847"(mRNA cleavage and polyadenylation specificity factor complex)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0006398"(mRNA 3'-end processing by stem-loop binding and cleavage)|go:"GO:0016020"(membrane)|refseq:NP_059133.1|refseq:NP_001309201.1|dip:DIP-42500N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2017/08/05	2017/08/10	rogid:7Df5H4dyiKBTRo4xiRZGbzGvzbk9606	rogid:RYiaQ8q9VM7htGre4S8PkSQaCz89606	rigid:WLhB6kKvejsSlmVe3NktbOulAXU	false	flag tag:n-n	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9H6E5	uniprotkb:Q99755	intact:EBI-2511680|ensembl:ENSP00000419607|uniprotkb:Q9H6H7|uniprotkb:Q7L583|uniprotkb:Q2NL65|uniprotkb:A1A527|intact:EBI-2809257|uniprotkb:A8K995	intact:EBI-726414|uniprotkb:Q99754|uniprotkb:Q99756|uniprotkb:B4DIN0|uniprotkb:A8K4Q0|ensembl:ENSP00000357883	psi-mi:stpap_human(display_long)|uniprotkb:TUT1(gene name)|psi-mi:TUT1(display_short)|uniprotkb:RBM21(gene name synonym)|uniprotkb:RNA-binding motif protein 21(gene name synonym)|uniprotkb:U6 snRNA-specific terminal uridylyltransferase 1(gene name synonym)	psi-mi:pi51a_human(display_long)|uniprotkb:PIP5K1A(gene name)|psi-mi:PIP5K1A(display_short)|uniprotkb:68 kDa type I phosphatidylinositol 4-phosphate 5-kinase alpha(gene name synonym)|uniprotkb:Phosphatidylinositol 4-phosphate 5-kinase type I alpha(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Mellman et al. (2008)	pubmed:18288197|doi:10.1038/nature06666|imex:IM-22001	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15687437|imex:IM-22001-5|dip:DIP-195767E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rcsb pdb:5WU6|rcsb pdb:5WU5|ensembl:ENSG00000149016(gene)|ensembl:ENST00000476907(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0004652"(polynucleotide adenylyltransferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0016180"(snRNA processing)|go:"GO:0016607"(nuclear speck)|go:"GO:0016779"(nucleotidyltransferase activity)|go:"GO:0017070"(U6 snRNA binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0031123"(RNA 3'-end processing)|go:"GO:0034477"(U6 snRNA 3'-end processing)|go:"GO:0046872"(metal ion binding)|go:"GO:0050265"(RNA uridylyltransferase activity)|go:"GO:0098789"(pre-mRNA cleavage required for polyadenylation)|go:"GO:1990817"(RNA adenylyltransferase activity)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002058(PAP/25A-associated)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034388|interpro:IPR035979|interpro:IPR036236|interpro:IPR043519|mint:Q9H6E5|rcsb pdb:2E5G|rcsb pdb:5WU1|rcsb pdb:5WU2|rcsb pdb:5WU3|rcsb pdb:5WU4|go:"GO:0005730"(nucleolus)|refseq:NP_073741.2|dip:DIP-53651N	refseq:NP_001129108.1|refseq:NP_001129109.1|refseq:NP_001129110.1|refseq:NP_003548.1|refseq:NP_001317618.1|ensembl:ENSG00000143398(gene)|ensembl:ENST00000368888(transcript)|go:"GO:0000285"(1-phosphatidylinositol-3-phosphate 5-kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006650"(glycerophospholipid metabolic process)|go:"GO:0006661"(phosphatidylinositol biosynthetic process)|go:"GO:0006909"(phagocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0008654"(phospholipid biosynthetic process)|go:"GO:0010761"(fibroblast migration)|go:"GO:0014066"(regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016308"(1-phosphatidylinositol-4-phosphate 5-kinase activity)|go:"GO:0016477"(cell migration)|go:"GO:0016607"(nuclear speck)|go:"GO:0019900"(kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0032587"(ruffle membrane)|go:"GO:0048041"(focal adhesion assembly)|go:"GO:0052810"(1-phosphatidylinositol-5-kinase activity)|go:"GO:0052812"(phosphatidylinositol-3,4-bisphosphate 5-kinase activity)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:0097178"(ruffle assembly)|interpro:IPR002498(Phosphatidylinositol-4-phosphate 5-kinase, core)|interpro:IPR023610|interpro:IPR027484|reactome:R-HSA-1660499|reactome:R-HSA-6811558|dip:DIP-60649N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2017/08/05	2017/08/10	rogid:7Df5H4dyiKBTRo4xiRZGbzGvzbk9606	rogid:jDE/jXrUlbohCr2mZjEgIxTVzjU9606	rigid:WLhB6kKvejsSlmVe3NktbOulAXU	false	flag tag:n-n	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9H6E5	uniprotkb:Q9UKF6	intact:EBI-2511680|ensembl:ENSP00000419607|uniprotkb:Q9H6H7|uniprotkb:Q7L583|uniprotkb:Q2NL65|uniprotkb:A1A527|intact:EBI-2809257|uniprotkb:A8K995	intact:EBI-1044699|uniprotkb:O14769|uniprotkb:Q96F36|uniprotkb:Q53RS2|ensembl:ENSP00000238112	psi-mi:stpap_human(display_long)|uniprotkb:TUT1(gene name)|psi-mi:TUT1(display_short)|uniprotkb:RBM21(gene name synonym)|uniprotkb:RNA-binding motif protein 21(gene name synonym)|uniprotkb:U6 snRNA-specific terminal uridylyltransferase 1(gene name synonym)	psi-mi:cpsf3_human(display_long)|uniprotkb:Cleavage and polyadenylation specificity factor 73 kDa subunit(gene name synonym)|uniprotkb:mRNA 3'-end-processing endonuclease CPSF-73(gene name synonym)|uniprotkb:CPSF3(gene name)|psi-mi:CPSF3(display_short)|uniprotkb:CPSF73(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Mellman et al. (2008)	pubmed:18288197|doi:10.1038/nature06666|imex:IM-22001	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15687485|imex:IM-22001-7|dip:DIP-195765E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rcsb pdb:5WU6|rcsb pdb:5WU5|ensembl:ENSG00000149016(gene)|ensembl:ENST00000476907(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0004652"(polynucleotide adenylyltransferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0016180"(snRNA processing)|go:"GO:0016607"(nuclear speck)|go:"GO:0016779"(nucleotidyltransferase activity)|go:"GO:0017070"(U6 snRNA binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0031123"(RNA 3'-end processing)|go:"GO:0034477"(U6 snRNA 3'-end processing)|go:"GO:0046872"(metal ion binding)|go:"GO:0050265"(RNA uridylyltransferase activity)|go:"GO:0098789"(pre-mRNA cleavage required for polyadenylation)|go:"GO:1990817"(RNA adenylyltransferase activity)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002058(PAP/25A-associated)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034388|interpro:IPR035979|interpro:IPR036236|interpro:IPR043519|mint:Q9H6E5|rcsb pdb:2E5G|rcsb pdb:5WU1|rcsb pdb:5WU2|rcsb pdb:5WU3|rcsb pdb:5WU4|go:"GO:0005730"(nucleolus)|refseq:NP_073741.2|dip:DIP-53651N	refseq:NP_057291.1|ensembl:ENSG00000119203(gene)|ensembl:ENST00000238112(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004521"(endoribonuclease activity)|go:"GO:0004534"(5'-3' exoribonuclease activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005847"(mRNA cleavage and polyadenylation specificity factor complex)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0006379"(mRNA cleavage)|go:"GO:0006398"(mRNA 3'-end processing by stem-loop binding and cleavage)|interpro:IPR021718|interpro:IPR022712|interpro:IPR036866|mint:Q9UKF6|rcsb pdb:2I7T|rcsb pdb:2I7V|rcsb pdb:6M8Q|rcsb pdb:6V4X|reactome:R-HSA-159231|reactome:R-HSA-72163|reactome:R-HSA-72187|reactome:R-HSA-73856|reactome:R-HSA-77595|go:"GO:0008409"(5'-3' exonuclease activity)|go:"GO:0046872"(metal ion binding)|interpro:IPR001279(Beta-lactamase-like)|interpro:IPR011108(RNA-metabolising metallo-beta-lactamase)|dip:DIP-42501N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2017/08/05	2017/08/10	rogid:7Df5H4dyiKBTRo4xiRZGbzGvzbk9606	rogid:lpTAUhlcFjFt2tHErN9igCjWTzs9606	rigid:f8K5ZbhBw8yWnIuAuQ1PhAhWqEM	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9H6E5	uniprotkb:Q99755	intact:EBI-2511680|ensembl:ENSP00000419607|uniprotkb:Q9H6H7|uniprotkb:Q7L583|uniprotkb:Q2NL65|uniprotkb:A1A527|intact:EBI-2809257|uniprotkb:A8K995	intact:EBI-726414|uniprotkb:Q99754|uniprotkb:Q99756|uniprotkb:B4DIN0|uniprotkb:A8K4Q0|ensembl:ENSP00000357883	psi-mi:stpap_human(display_long)|uniprotkb:TUT1(gene name)|psi-mi:TUT1(display_short)|uniprotkb:RBM21(gene name synonym)|uniprotkb:RNA-binding motif protein 21(gene name synonym)|uniprotkb:U6 snRNA-specific terminal uridylyltransferase 1(gene name synonym)	psi-mi:pi51a_human(display_long)|uniprotkb:PIP5K1A(gene name)|psi-mi:PIP5K1A(display_short)|uniprotkb:68 kDa type I phosphatidylinositol 4-phosphate 5-kinase alpha(gene name synonym)|uniprotkb:Phosphatidylinositol 4-phosphate 5-kinase type I alpha(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Mellman et al. (2008)	pubmed:18288197|doi:10.1038/nature06666|imex:IM-22001	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15687485|imex:IM-22001-7|dip:DIP-195765E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rcsb pdb:5WU6|rcsb pdb:5WU5|ensembl:ENSG00000149016(gene)|ensembl:ENST00000476907(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0004652"(polynucleotide adenylyltransferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0016180"(snRNA processing)|go:"GO:0016607"(nuclear speck)|go:"GO:0016779"(nucleotidyltransferase activity)|go:"GO:0017070"(U6 snRNA binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0031123"(RNA 3'-end processing)|go:"GO:0034477"(U6 snRNA 3'-end processing)|go:"GO:0046872"(metal ion binding)|go:"GO:0050265"(RNA uridylyltransferase activity)|go:"GO:0098789"(pre-mRNA cleavage required for polyadenylation)|go:"GO:1990817"(RNA adenylyltransferase activity)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002058(PAP/25A-associated)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034388|interpro:IPR035979|interpro:IPR036236|interpro:IPR043519|mint:Q9H6E5|rcsb pdb:2E5G|rcsb pdb:5WU1|rcsb pdb:5WU2|rcsb pdb:5WU3|rcsb pdb:5WU4|go:"GO:0005730"(nucleolus)|refseq:NP_073741.2|dip:DIP-53651N	refseq:NP_001129108.1|refseq:NP_001129109.1|refseq:NP_001129110.1|refseq:NP_003548.1|refseq:NP_001317618.1|ensembl:ENSG00000143398(gene)|ensembl:ENST00000368888(transcript)|go:"GO:0000285"(1-phosphatidylinositol-3-phosphate 5-kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006650"(glycerophospholipid metabolic process)|go:"GO:0006661"(phosphatidylinositol biosynthetic process)|go:"GO:0006909"(phagocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0008654"(phospholipid biosynthetic process)|go:"GO:0010761"(fibroblast migration)|go:"GO:0014066"(regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016308"(1-phosphatidylinositol-4-phosphate 5-kinase activity)|go:"GO:0016477"(cell migration)|go:"GO:0016607"(nuclear speck)|go:"GO:0019900"(kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0032587"(ruffle membrane)|go:"GO:0048041"(focal adhesion assembly)|go:"GO:0052810"(1-phosphatidylinositol-5-kinase activity)|go:"GO:0052812"(phosphatidylinositol-3,4-bisphosphate 5-kinase activity)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:0097178"(ruffle assembly)|interpro:IPR002498(Phosphatidylinositol-4-phosphate 5-kinase, core)|interpro:IPR023610|interpro:IPR027484|reactome:R-HSA-1660499|reactome:R-HSA-6811558|dip:DIP-60649N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2017/08/05	2017/08/10	rogid:7Df5H4dyiKBTRo4xiRZGbzGvzbk9606	rogid:jDE/jXrUlbohCr2mZjEgIxTVzjU9606	rigid:f8K5ZbhBw8yWnIuAuQ1PhAhWqEM	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)