#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P99999 uniprotkb:P16435 intact:EBI-446479|uniprotkb:A4D166|uniprotkb:P00001|uniprotkb:Q6NUR2|uniprotkb:Q6NX69|uniprotkb:Q96BV4|uniprotkb:B2R4I1|ensembl:ENSP00000307786|ensembl:ENSP00000386270|ensembl:ENSP00000387279 intact:EBI-726554|uniprotkb:Q9UDT3|uniprotkb:Q16455|uniprotkb:Q8N181|uniprotkb:Q9H3M8|uniprotkb:Q197M5|ensembl:ENSP00000378355|ensembl:ENSP00000389409|ensembl:ENSP00000389719|ensembl:ENSP00000390540|ensembl:ENSP00000395813|ensembl:ENSP00000399327|ensembl:ENSP00000399556|ensembl:ENSP00000404731|ensembl:ENSP00000409238|ensembl:ENSP00000414263|ensembl:ENSP00000419970 psi-mi:cyc_human(display_long)|uniprotkb:CYCS(gene name)|psi-mi:CYCS(display_short)|uniprotkb:CYC(gene name synonym) psi-mi:ncpr_human(display_long)|uniprotkb:POR(gene name)|psi-mi:POR(display_short)|uniprotkb:CYPOR(gene name synonym) psi-mi:"MI:0415"(enzymatic study) Huang et al. (2008) pubmed:18230729|doi:10.1073/pnas.0711621105|imex:IM-9065 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15682147|imex:IM-9065-1|dip:DIP-59165E - - psi-mi:"MI:0502"(enzyme target) psi-mi:"MI:0501"(enzyme) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_061820.1|dip:DIP-29683N|ensembl:ENSG00000172115(gene)|ensembl:ENST00000305786(transcript)|ensembl:ENST00000409409(transcript)|ensembl:ENST00000409764(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005829"(cytosol)|go:"GO:0006122"(mitochondrial electron transport, ubiquinol to cytochrome c)|go:"GO:0006123"(mitochondrial electron transport, cytochrome c to oxygen)|go:"GO:0006915"(apoptotic process)|go:"GO:0008635"(activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c)|go:"GO:0009055"(electron transfer activity)|go:"GO:0020037"(heme binding)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0045333"(cellular respiration)|go:"GO:0046872"(metal ion binding)|go:"GO:0070469"(respirasome)|interpro:IPR002327(Cytochrome c, class IA/ IB)|interpro:IPR009056(Cytochrome c, monohaem)|interpro:IPR036909|mint:P99999|rcsb pdb:1J3S|rcsb pdb:2N3Y|rcsb pdb:2N9I|rcsb pdb:2N9J|rcsb pdb:3NWV|rcsb pdb:3ZCF|rcsb pdb:3ZOO|rcsb pdb:5EXQ|rcsb pdb:5O10|rcsb pdb:5TY3|rcsb pdb:6DUJ|rcsb pdb:6ECJ|reactome:R-HSA-111457|reactome:R-HSA-111458|reactome:R-HSA-111459|reactome:R-HSA-111463|reactome:R-HSA-111464|reactome:R-HSA-2151201|reactome:R-HSA-3299685|reactome:R-HSA-5620971|reactome:R-HSA-5628897|reactome:R-HSA-611105|reactome:R-HSA-9627069|reactome:R-HSA-9707564 refseq:NP_000932.3|ensembl:ENSG00000127948(gene)|ensembl:ENST00000394893(transcript)|ensembl:ENST00000412064(transcript)|ensembl:ENST00000412521(transcript)|ensembl:ENST00000414186(transcript)|ensembl:ENST00000418341(transcript)|ensembl:ENST00000432753(transcript)|ensembl:ENST00000439963(transcript)|ensembl:ENST00000449920(transcript)|ensembl:ENST00000453773(transcript)|ensembl:ENST00000454934(transcript)|ensembl:ENST00000461988(transcript)|go:"GO:0003420"(regulation of growth plate cartilage chondrocyte proliferation)|go:"GO:0003958"(NADPH-hemoprotein reductase activity)|go:"GO:0004128"("cytochrome-b5 reductase activity, acting on NAD(P)H")|go:"GO:0005739"(mitochondrion)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006805"(xenobiotic metabolic process)|go:"GO:0007584"(response to nutrient)|go:"GO:0008941"(nitric oxide dioxygenase activity)|go:"GO:0009055"(electron transfer activity)|go:"GO:0009437"(carnitine metabolic process)|go:"GO:0009725"(response to hormone)|go:"GO:0009812"(flavonoid metabolic process)|go:"GO:0010181"(FMN binding)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0016709"("oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen")|go:"GO:0016787"(hydrolase activity)|go:"GO:0018393"(internal peptidyl-lysine acetylation)|go:"GO:0019395"(fatty acid oxidation)|go:"GO:0019899"(enzyme binding)|go:"GO:0022900"(electron transport chain)|go:"GO:0032332"(positive regulation of chondrocyte differentiation)|go:"GO:0032770"(positive regulation of monooxygenase activity)|go:"GO:0042493"|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043602"(nitrate catabolic process)|go:"GO:0045542"(positive regulation of cholesterol biosynthetic process)|go:"GO:0045880"(positive regulation of smoothened signaling pathway)|go:"GO:0046210"(nitric oxide catabolic process)|go:"GO:0047726"(iron-cytochrome-c reductase activity)|go:"GO:0050660"(flavin adenine dinucleotide binding)|go:"GO:0050661"(NADP binding)|go:"GO:0060192"(negative regulation of lipase activity)|go:"GO:0070988"(demethylation)|go:"GO:0071372"(cellular response to follicle-stimulating hormone stimulus)|go:"GO:0071375"(cellular response to peptide hormone stimulus)|go:"GO:0090031"(positive regulation of steroid hormone biosynthetic process)|go:"GO:0090346"(cellular organofluorine metabolic process)|interpro:IPR001094(Flavodoxin-like)|interpro:IPR001433("Oxidoreductase FAD/NAD(P)-binding")|interpro:IPR001709(Flavoprotein pyridine nucleotide cytochrome reductase)|interpro:IPR003097(FAD-binding, type 1)|interpro:IPR008254(Flavodoxin/nitric oxide synthase)|interpro:IPR017927|interpro:IPR017938|interpro:IPR023173|interpro:IPR023208|interpro:IPR029039|interpro:IPR039261|rcsb pdb:1B1C|rcsb pdb:3FJO|rcsb pdb:3QE2|rcsb pdb:3QFC|rcsb pdb:3QFR|rcsb pdb:3QFS|rcsb pdb:3QFT|rcsb pdb:5EMN|rcsb pdb:5FA6|reactome:R-HSA-211897|dip:DIP-29682N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/05 2017/08/10 rogid:vSMR7doWXd3VBP8jmhl6cUjccdY9606 rogid:Tgl0hfwgwo16Yw+kH4JIdIaRPpM9606 rigid:tl7KsA6BxNkkOQkO1WH3zyjnJI0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)