#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P18502	uniprotkb:Q9V496	intact:EBI-140029|uniprotkb:Q9V4W3|ensemblmetazoa:FBpp0088443	intact:EBI-147819|uniprotkb:Q8ST55|uniprotkb:Q8T6S6|uniprotkb:Q94907|ensemblmetazoa:FBpp0088252|ensemblmetazoa:FBpp0306689|ensemblmetazoa:FBpp0311463|ensemblmetazoa:FBpp0311464	psi-mi:ptc_drome(display_long)|uniprotkb:ptc(gene name)|psi-mi:ptc(display_short)|uniprotkb:CG2411(orf name)|uniprotkb:Hedgehog receptor(gene name synonym)	psi-mi:aplp_drome(display_long)|uniprotkb:apolpp(gene name)|psi-mi:apolpp(display_short)|uniprotkb:Retinoid- and fatty acid-binding glycoprotein(gene name synonym)|uniprotkb:RfaBp(gene name synonym)|uniprotkb:Rfabg(gene name synonym)|uniprotkb:CG11064(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Callejo et al. (2008)	pubmed:18198278|doi:10.1073/pnas.0705603105|imex:IM-9055	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15679770|imex:IM-9055-1|dip:DIP-59157E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_523661.2|flybase:FBgn0003892|dip:DIP-634N|ensemblmetazoa:FBgn0003892(gene)|ensemblmetazoa:FBtr0089427(transcript)|go:"GO:0001746"(Bolwig's organ morphogenesis)|go:"GO:0005119"(smoothened binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005929"(cilium)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0007367"(segment polarity determination)|go:"GO:0007411"(axon guidance)|go:"GO:0007455"(eye-antennal disc morphogenesis)|go:"GO:0007476"(imaginal disc-derived wing morphogenesis)|go:"GO:0008158"(hedgehog receptor activity)|go:"GO:0008406"(gonad development)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030228"(lipoprotein particle receptor activity)|go:"GO:0030707"(ovarian follicle cell development)|go:"GO:0035225"(determination of genital disc primordium)|go:"GO:0035332"(positive regulation of hippo signaling)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0048099"(anterior/posterior lineage restriction, imaginal disc)|go:"GO:0048100"(wing disc anterior/posterior pattern formation)|go:"GO:0055088"(lipid homeostasis)|go:"GO:0070273"(phosphatidylinositol-4-phosphate binding)|go:"GO:0097108"(hedgehog family protein binding)|go:"GO:2000274"(regulation of epithelial cell migration, open tracheal system)|interpro:IPR000731(Sterol-sensing 5TM box)|interpro:IPR003392(Patched)|interpro:IPR004766(Transmembrane receptor, patched)|reactome:R-DME-209338|reactome:R-DME-5610787|reactome:R-DME-5632681|reactome:R-DME-5632684	refseq:NP_001284720.1|refseq:NP_001284721.1|refseq:NP_524634.2|flybase:FBgn0087002|refseq:NP_001259085.1|dip:DIP-19190N|interpro:IPR015819(Lipid transport protein, beta-sheet shell)|interpro:IPR015817(Vitellinogen, open beta-sheet, subdomain 1)|ensemblmetazoa:FBgn0087002(gene)|ensemblmetazoa:FBtr0089188(transcript)|ensemblmetazoa:FBtr0334627(transcript)|ensemblmetazoa:FBtr0345296(transcript)|ensemblmetazoa:FBtr0345297(transcript)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005319"(lipid transporter activity)|go:"GO:0005504"(fatty acid binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0006869"(lipid transport)|go:"GO:0008017"(microtubule binding)|go:"GO:0010877"(lipid transport involved in lipid storage)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0019841"(retinol binding)|go:"GO:0020037"(heme binding)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0045178"(basal part of cell)|go:"GO:0045880"(positive regulation of smoothened signaling pathway)|go:"GO:0046872"(metal ion binding)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|interpro:IPR001747(Lipid transport protein, N-terminal)|interpro:IPR001846(von Willebrand factor, type D)|interpro:IPR009454(Lipid transport, open beta-sheet)|interpro:IPR011030(Vitellinogen, superhelical)|interpro:IPR015255(Vitellinogen, open beta-sheet)|interpro:IPR015816(Vitellinogen, beta-sheet N-terminal)	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	-	2017/08/05	2017/08/10	rogid:nSgw0TMBaqz8EOXgCCXdvffepz07227	rogid:tYbzddCXrOtYuwJdGDhWYeBYG6A7227	rigid:iGLn1N5cmRmSlnzGhfdSrfyFARk	false	green fluorescent protein tag:n-n	polyprotein fragment:26-706	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P18502	uniprotkb:Q9V496	intact:EBI-140029|uniprotkb:Q9V4W3|ensemblmetazoa:FBpp0088443	intact:EBI-147819|uniprotkb:Q8ST55|uniprotkb:Q8T6S6|uniprotkb:Q94907|ensemblmetazoa:FBpp0088252|ensemblmetazoa:FBpp0306689|ensemblmetazoa:FBpp0311463|ensemblmetazoa:FBpp0311464	psi-mi:ptc_drome(display_long)|uniprotkb:ptc(gene name)|psi-mi:ptc(display_short)|uniprotkb:CG2411(orf name)|uniprotkb:Hedgehog receptor(gene name synonym)	psi-mi:aplp_drome(display_long)|uniprotkb:apolpp(gene name)|psi-mi:apolpp(display_short)|uniprotkb:Retinoid- and fatty acid-binding glycoprotein(gene name synonym)|uniprotkb:RfaBp(gene name synonym)|uniprotkb:Rfabg(gene name synonym)|uniprotkb:CG11064(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Callejo et al. (2008)	pubmed:18198278|doi:10.1073/pnas.0705603105|imex:IM-9055	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15679770|imex:IM-9055-1|dip:DIP-59157E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_523661.2|flybase:FBgn0003892|dip:DIP-634N|ensemblmetazoa:FBgn0003892(gene)|ensemblmetazoa:FBtr0089427(transcript)|go:"GO:0001746"(Bolwig's organ morphogenesis)|go:"GO:0005119"(smoothened binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005929"(cilium)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0007367"(segment polarity determination)|go:"GO:0007411"(axon guidance)|go:"GO:0007455"(eye-antennal disc morphogenesis)|go:"GO:0007476"(imaginal disc-derived wing morphogenesis)|go:"GO:0008158"(hedgehog receptor activity)|go:"GO:0008406"(gonad development)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030228"(lipoprotein particle receptor activity)|go:"GO:0030707"(ovarian follicle cell development)|go:"GO:0035225"(determination of genital disc primordium)|go:"GO:0035332"(positive regulation of hippo signaling)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0048099"(anterior/posterior lineage restriction, imaginal disc)|go:"GO:0048100"(wing disc anterior/posterior pattern formation)|go:"GO:0055088"(lipid homeostasis)|go:"GO:0070273"(phosphatidylinositol-4-phosphate binding)|go:"GO:0097108"(hedgehog family protein binding)|go:"GO:2000274"(regulation of epithelial cell migration, open tracheal system)|interpro:IPR000731(Sterol-sensing 5TM box)|interpro:IPR003392(Patched)|interpro:IPR004766(Transmembrane receptor, patched)|reactome:R-DME-209338|reactome:R-DME-5610787|reactome:R-DME-5632681|reactome:R-DME-5632684	refseq:NP_001284720.1|refseq:NP_001284721.1|refseq:NP_524634.2|flybase:FBgn0087002|refseq:NP_001259085.1|dip:DIP-19190N|interpro:IPR015819(Lipid transport protein, beta-sheet shell)|interpro:IPR015817(Vitellinogen, open beta-sheet, subdomain 1)|ensemblmetazoa:FBgn0087002(gene)|ensemblmetazoa:FBtr0089188(transcript)|ensemblmetazoa:FBtr0334627(transcript)|ensemblmetazoa:FBtr0345296(transcript)|ensemblmetazoa:FBtr0345297(transcript)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005319"(lipid transporter activity)|go:"GO:0005504"(fatty acid binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0006869"(lipid transport)|go:"GO:0008017"(microtubule binding)|go:"GO:0010877"(lipid transport involved in lipid storage)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0019841"(retinol binding)|go:"GO:0020037"(heme binding)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0045178"(basal part of cell)|go:"GO:0045880"(positive regulation of smoothened signaling pathway)|go:"GO:0046872"(metal ion binding)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|interpro:IPR001747(Lipid transport protein, N-terminal)|interpro:IPR001846(von Willebrand factor, type D)|interpro:IPR009454(Lipid transport, open beta-sheet)|interpro:IPR011030(Vitellinogen, superhelical)|interpro:IPR015255(Vitellinogen, open beta-sheet)|interpro:IPR015816(Vitellinogen, beta-sheet N-terminal)	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	-	2017/08/05	2017/08/10	rogid:nSgw0TMBaqz8EOXgCCXdvffepz07227	rogid:tYbzddCXrOtYuwJdGDhWYeBYG6A7227	rigid:iGLn1N5cmRmSlnzGhfdSrfyFARk	false	green fluorescent protein tag:n-n	polyprotein fragment:707-3351	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)