#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P32233 uniprotkb:O75716 intact:EBI-8429215|intact:MINT-1857949|ensembl:ENSMUSP00000020741 intact:EBI-749295|uniprotkb:Q96KI2|uniprotkb:Q9UEN3|uniprotkb:Q9UP78|uniprotkb:A8K9H9|uniprotkb:Q5U0F8|intact:EBI-1046308|uniprotkb:Q9BUH4|ensembl:ENSP00000379964|ensembl:ENSP00000386928 psi-mi:drg1_mouse(display_long)|uniprotkb:Drg1(gene name)|psi-mi:Drg1(display_short)|uniprotkb:Drg(gene name synonym)|uniprotkb:Nedd3(gene name synonym)|uniprotkb:Nedd-3(gene name synonym)|uniprotkb:Neural precursor cell expressed developmentally down-regulated protein 3(gene name synonym)|uniprotkb:Translation factor GTPase DRG1(gene name synonym) psi-mi:stk16_human(display_long)|uniprotkb:STK16(gene name)|psi-mi:STK16(display_short)|uniprotkb:MPSK1(gene name synonym)|uniprotkb:PKL12(gene name synonym)|uniprotkb:TSF1(gene name synonym)|uniprotkb:Protein kinase PKL12(gene name synonym)|uniprotkb:Myristoylated and palmitoylated serine/threonine-protein kinase(gene name synonym)|uniprotkb:TGF-beta-stimulated factor 1(gene name synonym)|uniprotkb:hPSK(gene name synonym)|uniprotkb:Tyrosine-protein kinase STK16(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Eswaran et al. (2008) pubmed:18184589|doi:10.1016/j.str.2007.10.026|imex:IM-8968 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15679531|imex:IM-8968-4|dip:DIP-59080E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_031905.1|dip:DIP-29599N|ensembl:ENSMUSG00000020457(gene)|ensembl:ENSMUST00000020741(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0008017"(microtubule binding)|go:"GO:0016604"(nuclear body)|go:"GO:0030955"(potassium ion binding)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0042802"(identical protein binding)|go:"GO:1901673"(regulation of mitotic spindle assembly)|interpro:IPR004095(TGS)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006073(GTP1/OBG)|interpro:IPR006074(GTP1/OBG, conserved site)|interpro:IPR012675(Beta-grasp fold, ferredoxin-type)|interpro:IPR012676(TGS-like)|interpro:IPR027417|interpro:IPR031167|interpro:IPR031662|mint:P32233 refseq:NP_001008910.1|refseq:NP_001317142.1|ensembl:ENSG00000115661(gene)|ensembl:ENST00000396738(transcript)|ensembl:ENST00000409638(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005798"(Golgi-associated vesicle)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|rcsb pdb:2BUJ|dip:DIP-29598N psi-mi:"MI:0465"(dip) comment:mint|function:May play a role in cell proliferation, differentiation and death - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse)|taxid:10090(Mus musculus) - 2017/08/05 2017/08/10 rogid:ViVCcUfhMIkjzW35gT5SItGCMt010090 rogid:9eLCQQQFtAQVj2MUxyDLGkniiM49606 rigid:gqvGV/Un+eJ82gGwM8A2XvRlHcU false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P32233 uniprotkb:O75716 intact:EBI-8429215|intact:MINT-1857949|ensembl:ENSMUSP00000020741 intact:EBI-749295|uniprotkb:Q96KI2|uniprotkb:Q9UEN3|uniprotkb:Q9UP78|uniprotkb:A8K9H9|uniprotkb:Q5U0F8|intact:EBI-1046308|uniprotkb:Q9BUH4|ensembl:ENSP00000379964|ensembl:ENSP00000386928 psi-mi:drg1_mouse(display_long)|uniprotkb:Drg1(gene name)|psi-mi:Drg1(display_short)|uniprotkb:Drg(gene name synonym)|uniprotkb:Nedd3(gene name synonym)|uniprotkb:Nedd-3(gene name synonym)|uniprotkb:Neural precursor cell expressed developmentally down-regulated protein 3(gene name synonym)|uniprotkb:Translation factor GTPase DRG1(gene name synonym) psi-mi:stk16_human(display_long)|uniprotkb:STK16(gene name)|psi-mi:STK16(display_short)|uniprotkb:MPSK1(gene name synonym)|uniprotkb:PKL12(gene name synonym)|uniprotkb:TSF1(gene name synonym)|uniprotkb:Protein kinase PKL12(gene name synonym)|uniprotkb:Myristoylated and palmitoylated serine/threonine-protein kinase(gene name synonym)|uniprotkb:TGF-beta-stimulated factor 1(gene name synonym)|uniprotkb:hPSK(gene name synonym)|uniprotkb:Tyrosine-protein kinase STK16(gene name synonym) psi-mi:"MI:0096"(pull down) Eswaran et al. (2008) pubmed:18184589|doi:10.1016/j.str.2007.10.026|imex:IM-8968 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15679565|imex:IM-8968-2|dip:DIP-59080E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_031905.1|dip:DIP-29599N|ensembl:ENSMUSG00000020457(gene)|ensembl:ENSMUST00000020741(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0008017"(microtubule binding)|go:"GO:0016604"(nuclear body)|go:"GO:0030955"(potassium ion binding)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0042802"(identical protein binding)|go:"GO:1901673"(regulation of mitotic spindle assembly)|interpro:IPR004095(TGS)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006073(GTP1/OBG)|interpro:IPR006074(GTP1/OBG, conserved site)|interpro:IPR012675(Beta-grasp fold, ferredoxin-type)|interpro:IPR012676(TGS-like)|interpro:IPR027417|interpro:IPR031167|interpro:IPR031662|mint:P32233 refseq:NP_001008910.1|refseq:NP_001317142.1|ensembl:ENSG00000115661(gene)|ensembl:ENST00000396738(transcript)|ensembl:ENST00000409638(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005798"(Golgi-associated vesicle)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|rcsb pdb:2BUJ|dip:DIP-29598N psi-mi:"MI:0465"(dip) comment:mint|function:May play a role in cell proliferation, differentiation and death - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/05 2017/08/10 rogid:ViVCcUfhMIkjzW35gT5SItGCMt010090 rogid:9eLCQQQFtAQVj2MUxyDLGkniiM49606 rigid:gqvGV/Un+eJ82gGwM8A2XvRlHcU false sufficient binding region:1-65|tag:n-n his tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32233 uniprotkb:O75716 intact:EBI-8429215|intact:MINT-1857949|ensembl:ENSMUSP00000020741 intact:EBI-749295|uniprotkb:Q96KI2|uniprotkb:Q9UEN3|uniprotkb:Q9UP78|uniprotkb:A8K9H9|uniprotkb:Q5U0F8|intact:EBI-1046308|uniprotkb:Q9BUH4|ensembl:ENSP00000379964|ensembl:ENSP00000386928 psi-mi:drg1_mouse(display_long)|uniprotkb:Drg1(gene name)|psi-mi:Drg1(display_short)|uniprotkb:Drg(gene name synonym)|uniprotkb:Nedd3(gene name synonym)|uniprotkb:Nedd-3(gene name synonym)|uniprotkb:Neural precursor cell expressed developmentally down-regulated protein 3(gene name synonym)|uniprotkb:Translation factor GTPase DRG1(gene name synonym) psi-mi:stk16_human(display_long)|uniprotkb:STK16(gene name)|psi-mi:STK16(display_short)|uniprotkb:MPSK1(gene name synonym)|uniprotkb:PKL12(gene name synonym)|uniprotkb:TSF1(gene name synonym)|uniprotkb:Protein kinase PKL12(gene name synonym)|uniprotkb:Myristoylated and palmitoylated serine/threonine-protein kinase(gene name synonym)|uniprotkb:TGF-beta-stimulated factor 1(gene name synonym)|uniprotkb:hPSK(gene name synonym)|uniprotkb:Tyrosine-protein kinase STK16(gene name synonym) psi-mi:"MI:0018"(two hybrid) Eswaran et al. (2008) pubmed:18184589|doi:10.1016/j.str.2007.10.026|imex:IM-8968 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15679548|imex:IM-8968-3|dip:DIP-59080E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_031905.1|dip:DIP-29599N|ensembl:ENSMUSG00000020457(gene)|ensembl:ENSMUST00000020741(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0008017"(microtubule binding)|go:"GO:0016604"(nuclear body)|go:"GO:0030955"(potassium ion binding)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0042802"(identical protein binding)|go:"GO:1901673"(regulation of mitotic spindle assembly)|interpro:IPR004095(TGS)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006073(GTP1/OBG)|interpro:IPR006074(GTP1/OBG, conserved site)|interpro:IPR012675(Beta-grasp fold, ferredoxin-type)|interpro:IPR012676(TGS-like)|interpro:IPR027417|interpro:IPR031167|interpro:IPR031662|mint:P32233 refseq:NP_001008910.1|refseq:NP_001317142.1|ensembl:ENSG00000115661(gene)|ensembl:ENST00000396738(transcript)|ensembl:ENST00000409638(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005798"(Golgi-associated vesicle)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|rcsb pdb:2BUJ|dip:DIP-29598N psi-mi:"MI:0465"(dip) comment:mint|function:May play a role in cell proliferation, differentiation and death - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/05 2017/08/10 rogid:ViVCcUfhMIkjzW35gT5SItGCMt010090 rogid:9eLCQQQFtAQVj2MUxyDLGkniiM49606 rigid:gqvGV/Un+eJ82gGwM8A2XvRlHcU false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P32233 uniprotkb:O75716 intact:EBI-8429215|intact:MINT-1857949|ensembl:ENSMUSP00000020741 intact:EBI-749295|uniprotkb:Q96KI2|uniprotkb:Q9UEN3|uniprotkb:Q9UP78|uniprotkb:A8K9H9|uniprotkb:Q5U0F8|intact:EBI-1046308|uniprotkb:Q9BUH4|ensembl:ENSP00000379964|ensembl:ENSP00000386928 psi-mi:drg1_mouse(display_long)|uniprotkb:Drg1(gene name)|psi-mi:Drg1(display_short)|uniprotkb:Drg(gene name synonym)|uniprotkb:Nedd3(gene name synonym)|uniprotkb:Nedd-3(gene name synonym)|uniprotkb:Neural precursor cell expressed developmentally down-regulated protein 3(gene name synonym)|uniprotkb:Translation factor GTPase DRG1(gene name synonym) psi-mi:stk16_human(display_long)|uniprotkb:STK16(gene name)|psi-mi:STK16(display_short)|uniprotkb:MPSK1(gene name synonym)|uniprotkb:PKL12(gene name synonym)|uniprotkb:TSF1(gene name synonym)|uniprotkb:Protein kinase PKL12(gene name synonym)|uniprotkb:Myristoylated and palmitoylated serine/threonine-protein kinase(gene name synonym)|uniprotkb:TGF-beta-stimulated factor 1(gene name synonym)|uniprotkb:hPSK(gene name synonym)|uniprotkb:Tyrosine-protein kinase STK16(gene name synonym) psi-mi:"MI:0424"(protein kinase assay) Eswaran et al. (2008) pubmed:18184589|doi:10.1016/j.str.2007.10.026|imex:IM-8968 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15679588|imex:IM-8968-1|dip:DIP-59080E - - psi-mi:"MI:0502"(enzyme target) psi-mi:"MI:0501"(enzyme) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_031905.1|dip:DIP-29599N|ensembl:ENSMUSG00000020457(gene)|ensembl:ENSMUST00000020741(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0008017"(microtubule binding)|go:"GO:0016604"(nuclear body)|go:"GO:0030955"(potassium ion binding)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0042802"(identical protein binding)|go:"GO:1901673"(regulation of mitotic spindle assembly)|interpro:IPR004095(TGS)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006073(GTP1/OBG)|interpro:IPR006074(GTP1/OBG, conserved site)|interpro:IPR012675(Beta-grasp fold, ferredoxin-type)|interpro:IPR012676(TGS-like)|interpro:IPR027417|interpro:IPR031167|interpro:IPR031662|mint:P32233 refseq:NP_001008910.1|refseq:NP_001317142.1|ensembl:ENSG00000115661(gene)|ensembl:ENST00000396738(transcript)|ensembl:ENST00000409638(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005798"(Golgi-associated vesicle)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|rcsb pdb:2BUJ|dip:DIP-29598N psi-mi:"MI:0465"(dip) comment:mint|function:May play a role in cell proliferation, differentiation and death - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/05 2017/08/10 rogid:ViVCcUfhMIkjzW35gT5SItGCMt010090 rogid:9eLCQQQFtAQVj2MUxyDLGkniiM49606 rigid:gqvGV/Un+eJ82gGwM8A2XvRlHcU false - - - - psi-mi:"MI:0821"(molecular weight estimation by autoradiography) psi-mi:"MI:0821"(molecular weight estimation by autoradiography)