#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q7TS55 uniprotkb:Q7TS55 intact:EBI-523345|ensembl:ENSMUSP00000083251|uniprotkb:Q7TNY2|uniprotkb:Q80YG2 intact:EBI-523345|ensembl:ENSMUSP00000083251|uniprotkb:Q7TNY2|uniprotkb:Q80YG2 psi-mi:tnf18_mouse(display_long)|uniprotkb:Gitrl(gene name synonym)|uniprotkb:Tnfsf18(gene name)|psi-mi:Tnfsf18(display_short)|uniprotkb:GITR ligand(gene name synonym)|uniprotkb:Glucocorticoid-induced TNF-related ligand(gene name synonym) psi-mi:tnf18_mouse(display_long)|uniprotkb:Gitrl(gene name synonym)|uniprotkb:Tnfsf18(gene name)|psi-mi:Tnfsf18(display_short)|uniprotkb:GITR ligand(gene name synonym)|uniprotkb:Glucocorticoid-induced TNF-related ligand(gene name synonym) psi-mi:"MI:0114"(x-ray crystallography) Chattopadhyay et al. (2008) pubmed:18182486|doi:10.1073/pnas.0710529105|imex:IM-9049 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15679025|imex:IM-9049-1|dip:DIP-59150E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000066755(gene)|ensembl:ENSMUST00000086084(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0002309"(T cell proliferation involved in immune response)|go:"GO:0002687"(positive regulation of leukocyte migration)|go:"GO:0005125"(cytokine activity)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005886"(plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0010759"(positive regulation of macrophage chemotaxis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032813"(tumor necrosis factor receptor superfamily binding)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0042129"(regulation of T cell proliferation)|go:"GO:0042531"(positive regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0042802"(identical protein binding)|go:"GO:0043254"(regulation of protein-containing complex assembly)|go:"GO:0045785"(positive regulation of cell adhesion)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0090026"(positive regulation of monocyte chemotaxis)|go:"GO:2000329"(negative regulation of T-helper 17 cell lineage commitment)|go:"GO:2000508"(regulation of dendritic cell chemotaxis)|interpro:IPR006052(Tumor Necrosis Factor)|interpro:IPR008983(Tumour necrosis factor-like)|interpro:IPR042380|rcsb pdb:2Q8O|rcsb pdb:2QDN|rcsb pdb:3B9I|rcsb pdb:3FC0|rcsb pdb:7KHX|reactome:R-MMU-5669034|refseq:NP_899247.3|dip:DIP-29663N ensembl:ENSMUSG00000066755(gene)|ensembl:ENSMUST00000086084(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0002309"(T cell proliferation involved in immune response)|go:"GO:0002687"(positive regulation of leukocyte migration)|go:"GO:0005125"(cytokine activity)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005886"(plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0010759"(positive regulation of macrophage chemotaxis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032813"(tumor necrosis factor receptor superfamily binding)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0042129"(regulation of T cell proliferation)|go:"GO:0042531"(positive regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0042802"(identical protein binding)|go:"GO:0043254"(regulation of protein-containing complex assembly)|go:"GO:0045785"(positive regulation of cell adhesion)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0090026"(positive regulation of monocyte chemotaxis)|go:"GO:2000329"(negative regulation of T-helper 17 cell lineage commitment)|go:"GO:2000508"(regulation of dendritic cell chemotaxis)|interpro:IPR006052(Tumor Necrosis Factor)|interpro:IPR008983(Tumour necrosis factor-like)|interpro:IPR042380|rcsb pdb:2Q8O|rcsb pdb:2QDN|rcsb pdb:3B9I|rcsb pdb:3FC0|rcsb pdb:7KHX|reactome:R-MMU-5669034|refseq:NP_899247.3|dip:DIP-29663N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/05 2017/08/10 rogid:bOOKQ163jFyZaB/cyQNNauB6SQY10090 rogid:bOOKQ163jFyZaB/cyQNNauB6SQY10090 rigid:LT/bH0oaIH+l8Ixaiq2O4yIZVcM false - - - 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q7TS55 uniprotkb:Q7TS55 intact:EBI-523345|ensembl:ENSMUSP00000083251|uniprotkb:Q7TNY2|uniprotkb:Q80YG2 intact:EBI-523345|ensembl:ENSMUSP00000083251|uniprotkb:Q7TNY2|uniprotkb:Q80YG2 psi-mi:tnf18_mouse(display_long)|uniprotkb:Gitrl(gene name synonym)|uniprotkb:Tnfsf18(gene name)|psi-mi:Tnfsf18(display_short)|uniprotkb:GITR ligand(gene name synonym)|uniprotkb:Glucocorticoid-induced TNF-related ligand(gene name synonym) psi-mi:tnf18_mouse(display_long)|uniprotkb:Gitrl(gene name synonym)|uniprotkb:Tnfsf18(gene name)|psi-mi:Tnfsf18(display_short)|uniprotkb:GITR ligand(gene name synonym)|uniprotkb:Glucocorticoid-induced TNF-related ligand(gene name synonym) psi-mi:"MI:0071"(molecular sieving) Chattopadhyay et al. (2008) pubmed:18182486|doi:10.1073/pnas.0710529105|imex:IM-9049 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15679041|imex:IM-9049-2|dip:DIP-59150E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000066755(gene)|ensembl:ENSMUST00000086084(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0002309"(T cell proliferation involved in immune response)|go:"GO:0002687"(positive regulation of leukocyte migration)|go:"GO:0005125"(cytokine activity)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005886"(plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0010759"(positive regulation of macrophage chemotaxis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032813"(tumor necrosis factor receptor superfamily binding)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0042129"(regulation of T cell proliferation)|go:"GO:0042531"(positive regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0042802"(identical protein binding)|go:"GO:0043254"(regulation of protein-containing complex assembly)|go:"GO:0045785"(positive regulation of cell adhesion)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0090026"(positive regulation of monocyte chemotaxis)|go:"GO:2000329"(negative regulation of T-helper 17 cell lineage commitment)|go:"GO:2000508"(regulation of dendritic cell chemotaxis)|interpro:IPR006052(Tumor Necrosis Factor)|interpro:IPR008983(Tumour necrosis factor-like)|interpro:IPR042380|rcsb pdb:2Q8O|rcsb pdb:2QDN|rcsb pdb:3B9I|rcsb pdb:3FC0|rcsb pdb:7KHX|reactome:R-MMU-5669034|refseq:NP_899247.3|dip:DIP-29663N ensembl:ENSMUSG00000066755(gene)|ensembl:ENSMUST00000086084(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0002309"(T cell proliferation involved in immune response)|go:"GO:0002687"(positive regulation of leukocyte migration)|go:"GO:0005125"(cytokine activity)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005886"(plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0010759"(positive regulation of macrophage chemotaxis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032813"(tumor necrosis factor receptor superfamily binding)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0042129"(regulation of T cell proliferation)|go:"GO:0042531"(positive regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0042802"(identical protein binding)|go:"GO:0043254"(regulation of protein-containing complex assembly)|go:"GO:0045785"(positive regulation of cell adhesion)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0090026"(positive regulation of monocyte chemotaxis)|go:"GO:2000329"(negative regulation of T-helper 17 cell lineage commitment)|go:"GO:2000508"(regulation of dendritic cell chemotaxis)|interpro:IPR006052(Tumor Necrosis Factor)|interpro:IPR008983(Tumour necrosis factor-like)|interpro:IPR042380|rcsb pdb:2Q8O|rcsb pdb:2QDN|rcsb pdb:3B9I|rcsb pdb:3FC0|rcsb pdb:7KHX|reactome:R-MMU-5669034|refseq:NP_899247.3|dip:DIP-29663N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/05 2017/08/10 rogid:bOOKQ163jFyZaB/cyQNNauB6SQY10090 rogid:bOOKQ163jFyZaB/cyQNNauB6SQY10090 rigid:LT/bH0oaIH+l8Ixaiq2O4yIZVcM false - - - 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O35714 uniprotkb:Q7TS55 intact:EBI-523358|uniprotkb:Q9JKR1|uniprotkb:Q9JKR2|uniprotkb:Q9JKR3|ensembl:ENSMUSP00000099462 intact:EBI-523345|ensembl:ENSMUSP00000083251|uniprotkb:Q7TNY2|uniprotkb:Q80YG2 psi-mi:tnr18_mouse(display_long)|uniprotkb:Glucocorticoid-induced TNFR-related protein(gene name synonym)|uniprotkb:Tnfrsf18(gene name)|psi-mi:Tnfrsf18(display_short)|uniprotkb:Gitr(gene name synonym) psi-mi:tnf18_mouse(display_long)|uniprotkb:Gitrl(gene name synonym)|uniprotkb:Tnfsf18(gene name)|psi-mi:Tnfsf18(display_short)|uniprotkb:GITR ligand(gene name synonym)|uniprotkb:Glucocorticoid-induced TNF-related ligand(gene name synonym) psi-mi:"MI:0107"(surface plasmon resonance) Chattopadhyay et al. (2008) pubmed:18182486|doi:10.1073/pnas.0710529105|imex:IM-9049 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15679058|imex:IM-9049-3|dip:DIP-59152E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000041954(gene)|ensembl:ENSMUST00000103173(transcript)|go:"GO:0002687"(positive regulation of leukocyte migration)|go:"GO:0005031"(tumor necrosis factor-activated receptor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0042531"(positive regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045785"(positive regulation of cell adhesion)|interpro:IPR001368(TNFR/CD27/30/40/95 cysteine-rich region)|interpro:IPR022318|interpro:IPR034018|rcsb pdb:7KHX|reactome:R-MMU-5669034|refseq:NP_033426.1|refseq:NP_068820.1|dip:DIP-29666N ensembl:ENSMUSG00000066755(gene)|ensembl:ENSMUST00000086084(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0002309"(T cell proliferation involved in immune response)|go:"GO:0002687"(positive regulation of leukocyte migration)|go:"GO:0005125"(cytokine activity)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005886"(plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0010759"(positive regulation of macrophage chemotaxis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032813"(tumor necrosis factor receptor superfamily binding)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0042129"(regulation of T cell proliferation)|go:"GO:0042531"(positive regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0042802"(identical protein binding)|go:"GO:0043254"(regulation of protein-containing complex assembly)|go:"GO:0045785"(positive regulation of cell adhesion)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0090026"(positive regulation of monocyte chemotaxis)|go:"GO:2000329"(negative regulation of T-helper 17 cell lineage commitment)|go:"GO:2000508"(regulation of dendritic cell chemotaxis)|interpro:IPR006052(Tumor Necrosis Factor)|interpro:IPR008983(Tumour necrosis factor-like)|interpro:IPR042380|rcsb pdb:2Q8O|rcsb pdb:2QDN|rcsb pdb:3B9I|rcsb pdb:3FC0|rcsb pdb:7KHX|reactome:R-MMU-5669034|refseq:NP_899247.3|dip:DIP-29663N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/05 2017/08/10 rogid:Mt8VhWf8cmfG4p5PDdxkGIyunyQ10090 rogid:bOOKQ163jFyZaB/cyQNNauB6SQY10090 rigid:t6u3oMLADs6kM3I1wrNwwBtURd0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)